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Sandra Welch

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Sandra P Welch; Laura J Sim-Selley; Dana E Selley
Sphingosine-1-phosphate receptors as emerging targets for treatment of pain.
Laura J Sim-Selley; Paulette B Goforth; Mba U Mba; Timothy L Macdonald; Kevin R Lynch; Sheldon Milstien; Sarah Spiegel; Leslie S Satin; Sandra P Welch; Dana E Selley
Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.
Sandra P Welch
Interaction of the cannabinoid and opioid systems in the modulation of nociception.

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All Publications

2012: Sandra P Welch; Laura J Sim-Selley; Dana E Selley
Sphingosine-1-phosphate receptors as emerging targets for treatment of pain.
Biochemical pharmacology 2012;84(12):1551-62.
2009: Laura J Sim-Selley; Paulette B Goforth; Mba U Mba; Timothy L Macdonald; Kevin R Lynch; Sheldon Milstien; Sarah Spiegel; Leslie S Satin; Sandra P Welch; Dana E Selley
Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.
Journal of neurochemistry 2009;110(4):1191-202.
2009: Sandra P Welch
Interaction of the cannabinoid and opioid systems in the modulation of nociception.
International review of psychiatry (Abingdon, England) 2009;21(2):143-51.
2008: Victoria L Haller; David L Stevens; Sandra P Welch
Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase.
European journal of pharmacology 2008;600(1-3):50-8.
2008: Jovan Williams; Victoria L Haller; David L Stevens; Sandra P Welch
Decreased basal endogenous opioid levels in diabetic rodents: effects on morphine and delta-9-tetrahydrocannabinoid-induced antinociception.
European journal of pharmacology 2008;584(1):78-86.
2008: Matthew C Kren; Victoria L Haller; Sandra P Welch
The role of gonadal hormones on opioid receptor protein density in arthritic rats.
European journal of pharmacology 2008;578(2-3):177-84.
2008: Victoria L Haller; Marissa A Bernstein; Sandra P Welch
Chronic morphine treatment decreases the Cav1.3 subunit of the L-type calcium channel.
European journal of pharmacology 2008;578(2-3):101-7.
2007: Paul A Smith; Dana E Selley; Laura J Sim-Selley; Sandra P Welch
Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors.
European journal of pharmacology 2007;571(2-3):129-37.
2007: Melinda L Cox; Victoria L Haller; Sandra P Welch
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor.
European journal of pharmacology 2007;570(1-3):50-6.
2007: Melinda L Cox; Victoria L Haller; Sandra P Welch
Synergy between delta9-tetrahydrocannabinol and morphine in the arthritic rat.
European journal of pharmacology 2007;567(1-2):125-30.
2006: Victoria L Haller; Diana L Cichewicz; Sandra P Welch
Non-cannabinoid CB1, non-cannabinoid CB2 antinociceptive effects of several novel compounds in the PPQ stretch test in mice.
European journal of pharmacology 2006;546(1-3):60-8.
2006: I Jovan Williams; Sherita Edwards; Alex Rubo; Victoria L Haller; David L Stevens; Sandra P Welch
Time course of the enhancement and restoration of the analgesic efficacy of codeine and morphine by delta9-tetrahydrocannabinol.
European journal of pharmacology 2006;539(1-2):57-63.
2005: Diana L Cichewicz; Sandra P Welch; Forrest L Smith
Enhancement of transdermal fentanyl and buprenorphine antinociception by transdermal delta9-tetrahydrocannabinol.
European journal of pharmacology 2005;525(1-3):74-82.
2004: Diana L Cichewicz; Melinda L Cox; Sandra P Welch; Dana E Selley; Laura J Sim-Selley
Mu and delta opioid-stimulated [35S]GTP gamma S binding in brain and spinal cord of polyarthritic rats.
European journal of pharmacology 2004;504(1-2):33-8.
2004: Caroline E Bass; Sandra P Welch; Billy R Martin
Reversal of delta 9-tetrahydrocannabinol-induced tolerance by specific kinase inhibitors.
European journal of pharmacology 2004;496(1-3):99-108.
2004: Melinda L Cox; Sandra P Welch
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat.
European journal of pharmacology 2004;493(1-3):65-74.
2003: Diana L Cichewicz; Sandra P Welch
Modulation of oral morphine antinociceptive tolerance and naloxone-precipitated withdrawal signs by oral Delta 9-tetrahydrocannabinol.
The Journal of pharmacology and experimental therapeutics 2003;305(3):812-7.
2003: Matthew C Lee; Forrest L Smith; David L Stevens; Sandra P Welch
The role of several kinases in mice tolerant to delta 9-tetrahydrocannabinol.
The Journal of pharmacology and experimental therapeutics 2003;305(2):593-9.
2002: Forrest L Smith; Ruby R Javed; Mark J Elzey; Sandra P Welch; Dana E Selley; Laura J Sim-Selley; William L Dewey
Prolonged reversal of morphine tolerance with no reversal of dependence by protein kinase C inhibitors.
Brain research 2002;958(1):28-35.
2002: Rene Anikwue; John W Huffman; Zachary L Martin; Sandra P Welch
Decrease in efficacy and potency of nonsteroidal anti-inflammatory drugs by chronic delta(9)-tetrahydrocannabinol administration.
The Journal of pharmacology and experimental therapeutics 2002;303(1):340-6.
2001: V C Campbell; Sandra P Welch
The role of minoxidil on endogenous opioid peptides in the spinal cord: a putative co-agonist relationship between K-ATP openers and opioids.
European journal of pharmacology 2001;417(1-2):91-8.
2001: Diana L Cichewicz; Victoria L Haller; Sandra P Welch
Changes in opioid and cannabinoid receptor protein following short-term combination treatment with delta(9)-tetrahydrocannabinol and morphine.
The Journal of pharmacology and experimental therapeutics 2001;297(1):121-7.
2000: V C Campbell; William L Dewey; Sandra P Welch
Comparison of [(3)H]Glyburide binding with opiate analgesia, tolerance, and dependence in ICR and Swiss-Webster mice.
The Journal of pharmacology and experimental therapeutics 2000;295(3):1112-9.
2000: S J Houser; M Eads; J P Embrey; Sandra P Welch
Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide.
Brain research 2000;857(1-2):337-42.
1999: AB Lohmann; Sandra P Welch
ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides.
European journal of pharmacology 1999;385(2-3):119-27.
1999: Marissa A Bernstein; Sandra P Welch
A method for the determination of activated receptor phosphorylation state following in vivo drug treatment.
Brain research. Brain research protocols 1999;4(3):420-4.
1999: Sandra P Welch; M Eads
Synergistic interactions of endogenous opioids and cannabinoid systems.
Brain research 1999;848(1-2):183-90.
1999: AB Lohmann; Sandra P Welch
Antisenses to opioid receptors attenuate ATP-gated K(+) channel opener-induced antinociception.
European journal of pharmacology 1999;384(2-3):147-52.
1999: DJ Mason; J Lowe; Sandra P Welch
A diminution of delta9-tetrahydrocannabinol modulation of dynorphin A-(1-17) in conjunction with tolerance development.
European journal of pharmacology 1999;381(2-3):105-11.
1999: DJ Mason; J Lowe; Sandra P Welch
Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception.
European journal of pharmacology 1999;378(3):237-48.
1999: Diana L Cichewicz; Zachary L Martin; Forrest L Smith; Sandra P Welch
Enhancement mu opioid antinociception by oral delta9-tetrahydrocannabinol: dose-response analysis and receptor identification.
The Journal of pharmacology and experimental therapeutics 1999;289(2):859-67.
1998: Sandra P Welch; John W Huffman; J Lowe
Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1301-8.
1998: Forrest L Smith; Diana L Cichewicz; Zachary L Martin; Sandra P Welch
The enhancement of morphine antinociception in mice by delta9-tetrahydrocannabinol.
Pharmacology, biochemistry, and behavior 1998;60(2):559-66.
1998: Forrest L Smith; K Fujimori; J Lowe; Sandra P Welch
Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats.
Pharmacology, biochemistry, and behavior 1998;60(1):183-91.
1998: Marissa A Bernstein; Sandra P Welch
mu-Opioid receptor down-regulation and cAMP-dependent protein kinase phosphorylation in a mouse model of chronic morphine tolerance.
Brain research. Molecular brain research 1998;55(2):237-42.
1998: D W Rowen; J P Embrey; Charles H Moore; Sandra P Welch
Antisense oligodeoxynucleotides to the kappa1 receptor enhance delta9-THC-induced antinociceptive tolerance.
Pharmacology, biochemistry, and behavior 1998;59(2):399-404.
1998: Marissa A Bernstein; Sandra P Welch
Inhibition of protein phosphatases alters the expression of morphine tolerance in mice.
European journal of pharmacology 1998;341(2-3):173-7.
1997: G Pugh; DJ Mason; V Combs; Sandra P Welch
Involvement of dynorphin B in the antinociceptive effects of the cannabinoid CP55,940 in the spinal cord.
The Journal of pharmacology and experimental therapeutics 1997;281(2):730-7.
1997: Sandra P Welch; Forrest L Smith; William L Dewey
Morphine tolerance-induced modulation of [3H]glyburide binding to mouse brain and spinal cord.
Drug and alcohol dependence 1997;45(1-2):47-53.
1997: Sandra P Welch
Characterization of anandamide-induced tolerance: comparison to delta 9-THC-induced interactions with dynorphinergic systems.
Drug and alcohol dependence 1997;45(1-2):39-45.
1997: Marissa A Bernstein; Sandra P Welch
Effects of spinal versus supraspinal administration of cyclic nucleotide-dependent protein kinase inhibitors on morphine tolerance in mice.
Drug and alcohol dependence 1997;44(1):41-6.
1996: G Pugh; P B Smith; D S Dombrowski; Sandra P Welch
The role of endogenous opioids in enhancing the antinociception produced by the combination of delta 9-tetrahydrocannabinol and morphine in the spinal cord.
The Journal of pharmacology and experimental therapeutics 1996;279(2):608-16.
1996: M Imad Damaj; Sandra P Welch; Billy R Martin
Characterization and modulation of acute tolerance to nicotine in mice.
The Journal of pharmacology and experimental therapeutics 1996;277(1):454-61.
1995: Marissa A Bernstein; Sandra P Welch
Alterations in L-type calcium channels in the brain and spinal cord of acutely treated and morphine-tolerant mice.
Brain research 1995;696(1-2):83-8.
1995: G Pugh; Mary E Abood; Sandra P Welch
Antisense oligodeoxynucleotides to the kappa-1 receptor block the antinociceptive effects of delta 9-THC in the spinal cord.
Brain research 1995;689(1):157-8.
1995: M Imad Damaj; K R Creasy; Sandra P Welch; John A Rosecrans; Mario D Aceto; Billy R Martin
Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist.
Psychopharmacology 1995;120(4):483-90.
1995: Sandra P Welch; L D Dunlow; G S Patrick; Raj K Razdan
Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: blockade of delta 9-THC-induced antinociception.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1235-44.
1995: A Tripathi; Sandra P Welch
Blockade of the antinociceptive activity of centrally administered ketorolac by nor-binaltorphimine.
European journal of pharmacology 1995;278(1):27-32.
1995: Sandra P Welch; P P Bass
Modulation of free intracellular calcium levels [(Ca++)i] in brain and spinal cord of morphine-tolerant rats and mice.
Pharmacology, biochemistry, and behavior 1995;51(1):57-63.
1995: Sandra P Welch; C Thomas; G S Patrick
Modulation of cannabinoid-induced antinociception after intracerebroventricular versus intrathecal administration to mice: possible mechanisms for interaction with morphine.
The Journal of pharmacology and experimental therapeutics 1995;272(1):310-21.
1995: S A Cook; Sandra P Welch; Aron H Lichtman; Billy R Martin
Evaluation of cAMP involvement in cannabinoid-induced antinociception.
Life sciences 1995;56(23-24):2049-56.
1995: M Imad Damaj; Sandra P Welch; Billy R Martin
In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice.
Psychopharmacology 1995;117(1):67-73.
1994: Sandra P Welch
Blockade of cannabinoid-induced antinociception by naloxone benzoylhydrazone (NalBZH).
Pharmacology, biochemistry, and behavior 1994;49(4):929-34.
1994: G Pugh; Sandra P Welch; P P Bass
Modulation of free intracellular calcium and cAMP by morphine and cannabinoids, alone and in combination in mouse brain and spinal cord synaptosomes.
Pharmacology, biochemistry, and behavior 1994;49(4):1093-100.
1994: P B Smith; DR Compton; Sandra P Welch; Raj K Razdan; R Mechoulam; Billy R Martin
The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice.
The Journal of pharmacology and experimental therapeutics 1994;270(1):219-27.
1994: M Imad Damaj; Sandra P Welch; Billy R Martin
Nicotine-induced antinociception in mice: role of G-proteins and adenylate cyclase.
Pharmacology, biochemistry, and behavior 1994;48(1):37-42.
1994: P B Smith; Sandra P Welch; Billy R Martin
Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice.
The Journal of pharmacology and experimental therapeutics 1994;268(3):1381-7.
1994: Billy R Martin; Sandra P Welch; Mary E Abood
Progress toward understanding the cannabinoid receptor and its second messenger systems.
Advances in pharmacology (San Diego, Calif.) 1994;25():341-97.
1994: M A Saxen; Forrest L Smith; L D Dunlow; D S Dombrowski; Sandra P Welch
The hypothermic and antinociceptive effects of intrathecal injection of CGRP (8-37) in mice.
Life sciences 1994;55(21):1665-74.
1993: Sandra P Welch; L D Dunlow
Antinociceptive activity of intrathecally administered potassium channel openers and opioid agonists: a common mechanism of action?
The Journal of pharmacology and experimental therapeutics 1993;267(1):390-9.
1993: L A Uphouse; Sandra P Welch; C R Ward; E F Ellis; J P Embrey
Antinociceptive activity of intrathecal ketorolac is blocked by the kappa-opioid receptor antagonist, nor-binaltorphimine.
European journal of pharmacology 1993;242(1):53-8.
1993: Forrest L Smith; Sandra P Welch; D S Dombrowski; William L Dewey
The role of endogenous opioids as mediators of the hypothermic effects of intrathecally administered calcium and calcitonin gene-related peptide in mice.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1407-15.
1993: M Imad Damaj; Sandra P Welch; Billy R Martin
Involvement of calcium and L-type channels in nicotine-induced antinociception.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1330-8.
1993: Sandra P Welch
Blockade of cannabinoid-induced antinociception by norbinaltorphimine, but not N,N-diallyl-tyrosine-Aib-phenylalanine-leucine, ICI 174,864 or naloxone in mice.
The Journal of pharmacology and experimental therapeutics 1993;265(2):633-40.
1993: M A Saxen; Sandra P Welch; William L Dewey
The mouse paw withdrawal assay: a method for determining the effect of calcitonin gene-related peptide on cutaneous heat nociceptive latency time.
Life sciences 1993;53(5):397-405.
1992: Sandra P Welch; P P Bass; K G Olson; G Pugh
Morphine-induced modulation of calcitonin gene-related peptide levels.
Pharmacology, biochemistry, and behavior 1992;43(4):1107-16.
1992: Sandra P Welch; D L Stevens
Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice.
The Journal of pharmacology and experimental therapeutics 1992;262(1):10-8.
1992: Sandra P Welch; D L Stevens; William L Dewey
A proposed mechanism of action for the antinociceptive effect of intrathecally administered calcium in the mouse.
The Journal of pharmacology and experimental therapeutics 1992;260(1):117-27.
1991: Sandra P Welch; K G Olson
Salmon calcitonin-induced modulation of free intracellular calcium.
Pharmacology, biochemistry, and behavior 1991;39(3):641-8.
1991: Sandra P Welch; K G Olson
Opiate tolerance-induced modulation of free intracellular calcium in synaptosomes.
Life sciences 1991;48(19):1853-61.
1991: K G Olson; Sandra P Welch
The effects of dynorphin A (1-13) and U50, 488H on free intracellular calcium in guinea pig cerebellar synaptosomes.
Life sciences 1991;48(6):575-81.
1990: Sandra P Welch; W L Dewey
The activity of several peptide fragments of parathyroid hormone, alone and in combination with salmon calcitonin and morphine, in antinociceptive tests in the mouse.
The Journal of pharmacology and experimental therapeutics 1990;252(1):140-6.
1990: Sandra P Welch; D L Stevens; William L Dewey
Differential effects of calcitonin gene-related peptide in tests utilizing thermal versus nociceptive stimuli.
NIDA research monograph 1990;105():401.
1989: Sandra P Welch; A K Singha; William L Dewey
The antinociception produced by intrathecal morphine, calcium, A23187, U50,488H, [D-Ala2, N-Me-Phe4, Gly-ol]enkephalin and [D-Pen2, D-Pen5]enkephalin after intrathecal administration of calcitonin gene-related peptide in mice.
The Journal of pharmacology and experimental therapeutics 1989;251(1):1-8.
1989: Sandra P Welch; K G Olson; D L Stevens; William L Dewey
Modulation of synaptosomal free intracellular calcium in naive and morphine-tolerant mice: correlation of calcium modulation in vitro and in vivo to tolerance development.
NIDA research monograph 1989;95():552-3.
1988: F Lux; Sandra P Welch; D A Brase; William L Dewey
Interaction of morphine with intrathecally administered calcium and calcium antagonists: evidence for supraspinal endogenous opioid mediation of intrathecal calcium-induced antinociception in mice.
The Journal of pharmacology and experimental therapeutics 1988;246(2):500-7.
1988: Sandra P Welch; C W Cooper; William L Dewey
An investigation of the antinociceptive activity of calcitonin gene-related peptide alone and in combination with morphine: correlation to 45Ca++ uptake by synaptosomes.
The Journal of pharmacology and experimental therapeutics 1988;244(1):28-33.
1986: M L Adams; D A Brase; Sandra P Welch; William L Dewey
The role of endogenous peptides in the action of opioid analgesics.
Annals of emergency medicine 1986;15(9):1030-5.