Michael Weller

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Dumitru Claudia Alexandra; Weller Michael; Gulbins Erich
Ceramide metabolism determines glioma cell resistance to chemotherapy.
Roth Patrick; Kissel Maria; Herrmann Caroline; Eisele Günter; Leban Johann; Weller Michael; Schmidt Friederike
SC68896, a novel small molecule proteasome inhibitor, exerts antiglioma activity in vitro and in vivo.
Tritschler Isabel; Gramatzki Dorothee; Capper David; Mittelbronn Michel; Meyermann Richard; Saharinen Juha; Wick Wolfgang; Keski-Oja Jorma; Weller Michael
Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells.

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All Publications

2009: Dumitru Claudia Alexandra; Weller Michael; Gulbins Erich
Ceramide metabolism determines glioma cell resistance to chemotherapy.
Journal of cellular physiology 2009;221(3):688-95.
2009: Roth Patrick; Kissel Maria; Herrmann Caroline; Eisele Günter; Leban Johann; Weller Michael; Schmidt Friederike
SC68896, a novel small molecule proteasome inhibitor, exerts antiglioma activity in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(21):6609-18.
2009: Tritschler Isabel; Gramatzki Dorothee; Capper David; Mittelbronn Michel; Meyermann Richard; Saharinen Juha; Wick Wolfgang; Keski-Oja Jorma; Weller Michael
Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells.
International journal of cancer. Journal international du cancer 2009;125(3):530-40.
2009: Gramatzki D; Pantazis G; Schittenhelm J; Tabatabai G; Köhle C; Wick W; Schwarz M; Weller M; Tritschler I
Aryl hydrocarbon receptor inhibition downregulates the TGF-beta/Smad pathway in human glioblastoma cells.
Oncogene 2009;28(28):2593-605.
2009: Wick Antje; Pascher Christina; Wick Wolfgang; Jauch Tanja; Weller Michael; Bogdahn Ulrich; Hau Peter
Rechallenge with temozolomide in patients with recurrent gliomas.
Journal of neurology 2009;256(5):734-41.
2009: Mittelbronn Michel; Harter Patrick; Warth Arne; Lupescu Adrian; Schilbach Karin; Vollmann Henning; Capper David; Goeppert Benjamin; Frei Karl; Bertalanffy Helmut; Weller Michael; Meyermann Richard; Lang Florian; Simon Perikles
EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas.
Brain pathology (Zurich, Switzerland) 2009;19(2):195-204.
2009: Happold Caroline; Roth Patrick; Wick Wolfgang; Steinbach Joachim P; Linnebank Michael; Weller Michael; Eisele Günter
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
Journal of neuro-oncology 2009;92(1):45-8.
2009: Schittenhelm J; Beschorner R; Simon P; Tabatabai G; Herrmann C; Schlaszus H; Capper D; Weller M; Meyermann R; Mittelbronn M
Diagnostic value of WT1 in neuroepithelial tumours.
Neuropathology and applied neurobiology 2009;35(1):69-81.
2009: Roth T; Sokolov A N; Messias A; Roth P; Weller M; Trauzettel-Klosinski S
Comparing explorative saccade and flicker training in hemianopia: a randomized controlled study.
Neurology 2009;72(4):324-31.
2008: Happold Caroline; Ernemann Ulrike; Roth Patrick; Wick Wolfgang; Weller Michael; Schmidt Friederike
Anticoagulation for radiation-induced neurotoxicity revisited.
Journal of neuro-oncology 2008;90(3):357-62.
2008: Naumann Ulrike; Maass Philipp; Gleske Anne-Kathrin; Aulwurm Steffen; Weller Michael; Eisele Guenter
Glioma gene therapy with soluble transforming growth factor-beta receptors II and III.
International journal of oncology 2008;33(4):759-65.
2008: Tabatabai Ghazaleh; Herrmann Caroline; von Kürthy Gabriele; Mittelbronn Michel; Grau Stefan; Frank Brigitte; Möhle Robert; Weller Michael; Wick Wolfgang
VEGF-dependent induction of CD62E on endothelial cells mediates glioma tropism of adult haematopoietic progenitor cells.
Brain : a journal of neurology 2008;131(Pt 10):2579-95.
2008: Strelau Jens; Schmeer Corina; Peterziel Heike; Sackmann Tina; Herold-Mende Christel; Steiner Hans; Weller Michael; Unsicker Klaus
Expression and putative functions of GDF-15, a member of the TGF-beta superfamily, in human glioma and glioblastoma cell lines.
Cancer letters 2008;270(1):30-9.
2008: Rieger Johannes; Lemke Dieter; Maurer Gabriele; Weiler Markus; Frank Brigitte; Tabatabai Ghazaleh; Weller Michael; Wick Wolfgang
Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL.
Journal of neurochemistry 2008;106(6):2436-48.
2008: Roth Patrick; Happold Caroline; Eisele Günter; Nägele Thomas; Weller Michael; Luft Andreas R
A series of patients with subpial hemorrhage: clinical manifestation, neuroradiological presentation and therapeutic implications.
Journal of neurology 2008;255(7):1018-22.
2008: Teichgräber Volker; Ulrich Martina; Endlich Nicole; Riethmüller Joachim; Wilker Barbara; De Oliveira-Munding Cheyla Conceição; van Heeckeren Anna M; Barr Mark L; von Kürthy Gabriele; Schmid Kurt W; Weller Michael; Tümmler Burkhard; Lang Florian; Grassme Heike; Döring Gerd; Gulbins Erich
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis.
Nature medicine 2008;14(4):382-91.
2008: Schmidt Friederike; Knobbe Christiane B; Frank Brigitte; Wolburg Hartwig; Weller Michael
The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines.
Oncology reports 2008;19(4):1061-6.
2008: Weinmann L; Wischhusen J; Demma M J; Naumann U; Roth P; Dasmahapatra B; Weller M
A novel p53 rescue compound induces p53-dependent growth arrest and sensitises glioma cells to Apo2L/TRAIL-induced apoptosis.
Cell death and differentiation 2008;15(4):718-29.
2008: Schittenhelm J; Reifenberger G; Ritz R; Nägele T; Weller M; Pantazis G; Capper D; Beschorner R; Meyermann R; Mittelbronn M
Primary anaplastic ganglioglioma with a small-cell glioblastoma component.
Clinical neuropathology 2008;27(2):91-5.
2008: Tabatabai Ghazaleh; Schöber Wolfgang; Ernemann Ulrike; Weller Michael; Krüger Rejko
Vertebral artery dissection presenting with ispilateral acute C5 and C6 sensorimotor radiculopathy: A case report.
Cases journal 2008;1(1):139.
2008: Broetz Doris; Hahn Ulrich; Maschke Evelin; Wick Wolfgang; Kueker Wilhelm; Weller Michael
Lumbar disk prolapse: response to mechanical physiotherapy in the absence of changes in magnetic resonance imaging. Report of 11 cases.
NeuroRehabilitation 2008;23(3):289-94.
2007: Weller Michael; Berger Hilmar; Hartmann Christian; Schramm Johannes; Westphal Manfred; Simon Matthias; Goldbrunner Roland; Krex Dietmar; Steinbach Joachim P; Ostertag Christoph B; Loeffler Markus; Pietsch Torsten; von Deimling Andreas;
Combined 1p/19q loss in oligodendroglial tumors: predictive or prognostic biomarker?
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):6933-7.
2007: Mittelbronn Michel; Schittenhelm Jens; Lemke Dieter; Ritz Rainer; Nägele Thomas; Weller Michael; Meyermann Richard; Beschorner Rudi
Low grade ganglioglioma rapidly progressing to a WHO grade IV tumor showing malignant transformation in both astroglial and neuronal cell components.
Neuropathology : official journal of the Japanese Society of Neuropathology 2007;27(5):463-7.
2007: Mittelbronn Michel; Simon Perikles; Löffler Christian; Capper David; Bunz Benedikt; Harter Patrick; Schlaszus Holger; Schleich Ariane; Tabatabai Ghazaleh; Goeppert Benjamin; Meyermann Richard; Weller Michael; Wischhusen Jörg
Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells.
Journal of neuroimmunology 2007;189(1-2):50-8.
2007: Grammatikos Georgios; Teichgräber Volker; Carpinteiro Alexander; Trarbach Tanja; Weller Michael; Hengge Ulrich R; Gulbins Erich
Overexpression of acid sphingomyelinase sensitizes glioma cells to chemotherapy.
Antioxidants & redox signaling 2007;9(9):1449-56.
2007: Wick Antje; Felsberg Jörg; Steinbach Joachim P; Herrlinger Ulrich; Platten Michael; Blaschke Britta; Meyermann Richard; Reifenberger Guido; Weller Michael; Wick Wolfgang
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(22):3357-61.
2007: Mehling Matthias; Simon Perikles; Mittelbronn Michel; Meyermann Richard; Ferrone Soldano; Weller Michael; Wiendl Heinz
WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism?
Acta neuropathologica 2007;114(2):111-9.
2007: Tran Thomas-Toan; Uhl Martin; Ma Jing Ying; Janssen Lisa; Sriram Venkataraman; Aulwurm Steffen; Kerr Irene; Lam Andrew; Webb Heather K; Kapoun Ann M; Kizer Darin E; McEnroe Glenn; Hart Barry; Axon Jonathan; Murphy Alison; Chakravarty Sarvajit; Dugar Sundeep; Protter Andrew A; Higgins Linda S; Wick Wolfgang; Weller Michael; Wong Darren H
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.
Neuro-oncology 2007;9(3):259-70.
2007: Mittelbronn M; Capper D; Bunz B; Dietz K; Goeppert B; Ajaaj R; Tabatabai G; Stubenvoll F; Schlaszus H; Merseburger A S; Becker R; Freudenstein D; Wick W; Weller M; Meyermann R; Simon P
De novo erythropoietin receptor (EPO-R) expression in human neoplastic glial cells decreases with grade of malignancy but is favourably associated with patient survival.
Neuropathology and applied neurobiology 2007;33(3):299-307.
2007: Warth Arne; Simon Perikles; Capper David; Goeppert Benjamin; Tabatabai Ghazaleh; Herzog Hajo; Dietz Klaus; Stubenvoll Florian; Ajaaj Rami; Becker Ralf; Weller Michael; Meyermann Richard; Wolburg Hartwig; Mittelbronn Michel
Expression pattern of the water channel aquaporin-4 in human gliomas is associated with blood-brain barrier disturbance but not with patient survival.
Journal of neuroscience research 2007;85(6):1336-46.
2007: Roth Patrick; Mittelbronn Michel; Wick Wolfgang; Meyermann Richard; Tatagiba Marcos; Weller Michael
Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1.
Cancer research 2007;67(8):3540-4.
2007: Broetz Doris; Eichner Martin; Gasser Thomas; Weller Michael; Steinbach Joachim P
Radicular and nonradicular back pain in Parkinson's disease: a controlled study.
Movement disorders : official journal of the Movement Disorder Society 2007;22(6):853-6.
2007: Burghardt Isabel; Tritschler Felix; Opitz Christiane A; Frank Brigitte; Weller Michael; Wick Wolfgang
Pirfenidone inhibits TGF-beta expression in malignant glioma cells.
Biochemical and biophysical research communications 2007;354(2):542-7.
2007: Tabatabai Ghazaleh; Frank Brigitte; Wick Antje; Lemke Dieter; von Kürthy Gabriele; Obermüller Ulrike; Heckl Stefan; Christ Gunter; Weller Michael; Wick Wolfgang
Synergistic antiglioma activity of radiotherapy and enzastaurin.
Annals of neurology 2007;61(2):153-61.
2007: Naumann U; Bähr O; Wolburg H; Altenberend S; Wick W; Liston P; Ashkenazi A; Weller M
Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice.
Gene therapy 2007;14(2):147-61.
2007: Roos W P; Batista L F Z; Naumann S C; Wick W; Weller M; Menck C F M; Kaina B
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
Oncogene 2007;26(2):186-97.
2007: Rieger Johannes; Frank Brigitte; Weller Michael; Wick Wolfgang
Mechanisms of resistance of human glioma cells to Apo2 ligand/TNF-related apoptosis-inducing ligand.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(1-4):23-34.
2006: Scheel Birgit; Aulwurm Steffen; Probst Jochen; Stitz Lothar; Hoerr Ingmar; Rammensee Hans-Georg; Weller Michael; Pascolo Steve
Therapeutic anti-tumor immunity triggered by injections of immunostimulating single-stranded RNA.
European journal of immunology 2006;36(10):2807-16.
2006: Herrlinger Ulrich; Rieger Johannes; Koch Dorothee; Loeser Simon; Blaschke Britta; Kortmann Rolf-Dieter; Steinbach Joachim P; Hundsberger Thomas; Wick Wolfgang; Meyermann Richard; Tan Ta-Chih; Sommer Clemens; Bamberg Michael; Reifenberger Guido; Weller Michael
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(27):4412-7.
2006: Eisele Günter; Wischhusen Jörg; Mittelbronn Michel; Meyermann Richard; Waldhauer Inja; Steinle Alexander; Weller Michael; Friese Manuel A
TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells.
Brain : a journal of neurology 2006;129(Pt 9):2416-25.
2006: Tabatabai Ghazaleh; Frank Brigitte; Möhle Robert; Weller Michael; Wick Wolfgang
Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.
Brain : a journal of neurology 2006;129(Pt 9):2426-35.
2006: Grassmé Heike; Jin Jianmin; Wilker Barbara; von Kürthy Gabriele; Wick Wolfgang; Weller Michael; Möröy Tarik; Gulbins Erich
Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1.
Cellular microbiology 2006;8(7):1096-105.
2006: Weiler M; Bähr O; Hohlweg U; Naumann U; Rieger J; Huang H; Tabatabai G; Krell H W; Ohgaki H; Weller M; Wick W
BCL-xL: time-dependent dissociation between modulation of apoptosis and invasiveness in human malignant glioma cells.
Cell death and differentiation 2006;13(7):1156-69.
2006: Eberhardt Olaf; Naegele Thomas; Raygrotzki Sabine; Weller Michael; Ernemann Ulrike
Stenting of vertebrobasilar arteries in symptomatic atherosclerotic disease and acute occlusion: case series and review of the literature.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2006;43(6):1145-54.
2006: Naumann U; Huang H; Wolburg H; Wischhusen J; Weit S; Ohgaki H; Weller M
PCTAIRE3: a putative mediator of growth arrest and death induced by CTS-1, a dominant-positive p53-derived synthetic tumor suppressor, in human malignant glioma cells.
Cancer gene therapy 2006;13(5):469-78.
2006: Roth Patrick; Aulwurm Steffen; Gekel Isabella; Beier Dagmar; Sperry Roxanne G; Mittelbronn Michel; Meyermann Richard; Beaman Kenneth D; Weller Michael; Wischhusen Jörg
Regeneration and tolerance factor: a novel mediator of glioblastoma-associated immunosuppression.
Cancer research 2006;66(7):3852-8.
2006: Aulwurm Steffen; Wischhusen Jörg; Friese Manuel; Borst Jannie; Weller Michael
Immune stimulatory effects of CD70 override CD70-mediated immune cell apoptosis in rodent glioma models and confer long-lasting antiglioma immunity in vivo.
International journal of cancer. Journal international du cancer 2006;118(7):1728-35.
2006: Schmidt F; Fischer J; Herrlinger U; Dietz K; Dichgans J; Weller M
PCV chemotherapy for recurrent glioblastoma.
Neurology 2006;66(4):587-9.
2006: Hermisson Mirjam; Klumpp Andrea; Wick Wolfgang; Wischhusen Jörg; Nagel Georg; Roos Wynand; Kaina Bernd; Weller Michael
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
Journal of neurochemistry 2006;96(3):766-76.
2006: Ernemann Ulrike; Rieger Johannes; Tatagiba Marcos; Weller Michael
An MRI view of a ruptured dermoid cyst.
Neurology 2006;66(2):270.
2006: Steinbach J P; Blaicher H-P; Herrlinger U; Wick W; Nägele T; Meyermann R; Tatagiba M; Bamberg M; Dichgans J; Karnath H-O; Weller M
Surviving glioblastoma for more than 5 years: the patient's perspective.
Neurology 2006;66(2):239-42.
2006: Waltereit Robert; Welzl Hans; Dichgans Johannes; Lipp Hans-Peter; Schmidt Werner J; Weller Michael
Enhanced episodic-like memory and kindling epilepsy in a rat model of tuberous sclerosis.
Journal of neurochemistry 2006;96(2):407-13.
2006: Wick Wolfgang; Naumann Ulrike; Weller Michael
Transforming growth factor-beta: a molecular target for the future therapy of glioblastoma.
Current pharmaceutical design 2006;12(3):341-9.
2005: Weller Michael; Steinbach Joachim P; Wick Wolfgang
Temozolomide: a milestone in the pharmacotherapy of brain tumors.
Future oncology (London, England) 2005;1(6):747-54.
2005: Ritz Rainer; Müller Martin; Weller Michael; Dietz Klaus; Kuci Selim; Roser Florian; Tatagiba Marcos
Hypericin: a promising fluorescence marker for differentiating between glioblastoma and neurons in vitro.
International journal of oncology 2005;27(6):1543-9.
2005: Grosse-Hovest Ludger; Wick Wolfgang; Minoia Rosa; Weller Michael; Rammensee Hans-Georg; Brem Gottfried; Jung Gundram
Supraagonistic, bispecific single-chain antibody purified from the serum of cloned, transgenic cows induces T-cell-mediated killing of glioblastoma cells in vitro and in vivo.
International journal of cancer. Journal international du cancer 2005;117(6):1060-4.
2005: Danielyan Lusine; Mueller Lars; Proksch Barbara; Kabisch Daniela; Weller Michael; Wiesinger Heinrich; Buniatian Gayane H; Gleiter Christoph H
Similar protective effects of BQ-123 and erythropoietin on survival of neural cells and generation of neurons upon hypoxic injury.
European journal of cell biology 2005;84(11):907-13.
2005: Wiendl Heinz; Feger Ute; Mittelbronn Michel; Jack Carolyn; Schreiner Bettina; Stadelmann Christine; Antel Jack; Brueck Wolfgang; Meyermann Richard; Bar-Or Amit; Kieseier Bernd C; Weller Michael
Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity.
Brain : a journal of neurology 2005;128(Pt 11):2689-704.
2005: Küker W; Nägele T; Thiel E; Weller M; Herrlinger U
Primary central nervous system lymphomas (PCNSL): MRI response criteria revised.
Neurology 2005;65(7):1129-31.
2005: Weller M
[Standards and new developments in the chemotherapy of glioblastomas]
Deutsche medizinische Wochenschrift (1946) 2005;130(40):2270-4.
2005: Tabatabai Ghazaleh; Bähr Oliver; Möhle Robert; Eyüpoglu Ilker Y; Boehmler Andreas M; Wischhusen Jörg; Rieger Johannes; Blümcke Ingmar; Weller Michael; Wick Wolfgang
Lessons from the bone marrow: how malignant glioma cells attract adult haematopoietic progenitor cells.
Brain : a journal of neurology 2005;128(Pt 9):2200-11.
2005: Wick Wolfgang; Menn Oliver; Meisner Christoph; Steinbach Joachim; Hermisson Mirjam; Tatagiba Marcos; Weller Michael
Pharmacotherapy of epileptic seizures in glioma patients: who, when, why and how long?
Onkologie 2005;28(8-9):391-6.
2005: Beier Christoph P; Wischhusen Jörg; Gleichmann Marc; Gerhardt Ellen; Pekanovic Ana; Krueger Andreas; Taylor Verdon; Suter Ueli; Krammer Peter H; Endres Matthias; Weller Michael; Schulz Jörg B
FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(29):6765-74.
2005: Wischhusen Jörg; Friese Manuel A; Mittelbronn Michel; Meyermann Richard; Weller Michael
HLA-E protects glioma cells from NKG2D-mediated immune responses in vitro: implications for immune escape in vivo.
Journal of neuropathology and experimental neurology 2005;64(6):523-8.
2005: Herrlinger Ulrich; Küker Wilhelm; Uhl Martin; Blaicher Hans-Peter; Karnath Hans-Otto; Kanz Lothar; Bamberg Michael; Weller Michael;
NOA-03 trial of high-dose methotrexate in primary central nervous system lymphoma: final report.
Annals of neurology 2005;57(6):843-7.
2005: Eyüpoglu Ilker Y; Hahnen Eric; Buslei Rolf; Siebzehnrübl Florian A; Savaskan Nicolai E; Lüders Mike; Tränkle Christian; Wick Wolfgang; Weller Michael; Fahlbusch Rudolf; Blümcke Ingmar
Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo.
Journal of neurochemistry 2005;93(4):992-9.
2005: Wischhusen Jörg; Schneider Dagmar; Mittelbronn Michel; Meyermann Richard; Engelmann Hartmut; Jung Gundram; Wiendl Heinz; Weller Michael
Death receptor-mediated apoptosis in human malignant glioma cells: modulation by the CD40/CD40L system.
Journal of neuroimmunology 2005;162(1-2):28-42.
2005: Küker Wilhelm; Nägele Thomas; Korfel Agnieska; Heckl Stefan; Thiel Eckhard; Bamberg Michael; Weller Michael; Herrlinger Ulrich
Primary central nervous system lymphomas (PCNSL): MRI features at presentation in 100 patients.
Journal of neuro-oncology 2005;72(2):169-77.
2005: Herrlinger Ulrich; Steinbrecher A; Rieger J; Hau P; Kortmann R-D; Meyermann R; Schabet M; Bamberg M; Dichgans J; Bogdahn U; Weller M
Adult medulloblastoma: prognostic factors and response to therapy at diagnosis and at relapse.
Journal of neurology 2005;252(3):291-9.
2005: Steinbach Joachim P; Wolburg Hartwig; Klumpp Andrea; Weller Michael
Hypoxia sensitizes human malignant glioma cells towards CD95L-induced cell death.
Journal of neurochemistry 2005;92(6):1340-9.
2005: Uhl Martin; Weiler Markus; Wick Wolfgang; Jacobs Andreas H; Weller Michael; Herrlinger Ulrich
Migratory neural stem cells for improved thymidine kinase-based gene therapy of malignant gliomas.
Biochemical and biophysical research communications 2005;328(1):125-9.
2005: Herrlinger Ulrich; Rieger Johannes; Steinbach Joachim P; Nägele Thomas; Dichgans Johannes; Weller Michael
UKT-04 trial of continuous metronomic low-dose chemotherapy with methotrexate and cyclophosphamide for recurrent glioblastoma.
Journal of neuro-oncology 2005;71(3):295-9.
2005: Herrlinger Ulrich; Korfel Agnieszka; Hebart Holger; Schlegel Uwe; Plasswilm Ludwig; Illerhaus Gerald; Finke Jürgen; Krüger William; Montemurro Michael; Wolf Timo; Thiel Eckhart; Bamberg Michael; Weller Michael; Kanz Lothar;
Meeting report: primary central nervous system lymphoma: standards of care and future perspectives.
Onkologie 2005;28(2):109-11.
2005: Mitsdoerffer Meike; Schreiner Bettina; Kieseier Bernd C; Neuhaus Oliver; Dichgans Johannes; Hartung Hans-Peter; Weller Michael; Wiendl Heinz
Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-beta in vitro and in vivo: rationale for the therapy of multiple sclerosis.
Journal of neuroimmunology 2005;159(1-2):155-64.
2005: Duffner Frank; Ritz Rainer; Freudenstein Dirk; Weller Michael; Dietz Klaus; Wessels Johannes
Specific intensity imaging for glioblastoma and neural cell cultures with 5-aminolevulinic acid-derived protoporphyrin IX.
Journal of neuro-oncology 2005;71(2):107-11.
2004: Wick Wolfgang; Wild-Bode Christine; Frank Brigitte; Weller Michael
BCL-2-induced glioma cell invasiveness depends on furin-like proteases.
Journal of neurochemistry 2004;91(6):1275-83.
2004: Wick Antje; Wick Wolfgang; Hirrlinger Johannes; Gerhardt Ellen; Dringen Ralf; Dichgans Johannes; Weller Michael; Schulz Jörg B
Chemotherapy-induced cell death in primary cerebellar granule neurons but not in astrocytes: in vitro paradigm of differential neurotoxicity.
Journal of neurochemistry 2004;91(5):1067-74.
2004: Naumann U; Wischhusen J; Weit S; Rieger J; Wolburg H; Massing U; Weller M
Alkylphosphocholine-induced glioma cell death is BCL-X(L)-sensitive, caspase-independent and characterized by massive cytoplasmic vacuole formation.
Cell death and differentiation 2004;11(12):1326-41.
2004: Steinbach Joachim P; Weller Michael
Apoptosis in gliomas: molecular mechanisms and therapeutic implications.
Journal of neuro-oncology 2004;70(2):245-54.
2004: Uhl Martin; Aulwurm Steffen; Wischhusen Jörg; Weiler Markus; Ma Jing Ying; Almirez Ramona; Mangadu Ruban; Liu Yu-Wang; Platten Michael; Herrlinger Ulrich; Murphy Alison; Wong Darren H; Wick Wolfgang; Higgins Linda S; Weller Michael
SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo.
Cancer research 2004;64(21):7954-61.
2004: Friese M A; Steinle A; Weller M
The innate immune response in the central nervous system and its role in glioma immune surveillance.
Onkologie 2004;27(5):487-91.
2004: Wick Wolfgang; Wick Antje; Küker Wilhelm; Dichgans Johannes; Weller Michael
Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.
Journal of neuro-oncology 2004;70(1):73-5.
2004: Friese Manuel A; Wischhusen Jörg; Wick Wolfgang; Weiler Markus; Eisele Günter; Steinle Alexander; Weller Michael
RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.
Cancer research 2004;64(20):7596-603.
2004: Schreiner Bettina; Mitsdoerffer Meike; Kieseier Bernd C; Chen Lieping; Hartung Hans-Peter; Weller Michael; Wiendl Heinz
Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis.
Journal of neuroimmunology 2004;155(1-2):172-82.
2004: Steinbach Joachim P; Eisenmann Christine; Klumpp Andrea; Weller Michael
Co-inhibition of epidermal growth factor receptor and type 1 insulin-like growth factor receptor synergistically sensitizes human malignant glioma cells to CD95L-induced apoptosis.
Biochemical and biophysical research communications 2004;321(3):524-30.
2004: Herrlinger Ulrich; Förschler Heike; Küker Wilhelm; Meyermann Richard; Bamberg Michael; Dichgans Johannes; Weller Michael
Leptomeningeal metastasis: survival and prognostic factors in 155 patients.
Journal of the neurological sciences 2004;223(2):167-78.
2004: Eberhardt O; Küker W; Dichgans J; Weller M
HSV-2 sacral radiculitis (Elsberg syndrome).
Neurology 2004;63(4):758-9.
2004: Küker Wilhelm; Weller Michael; Klose Uwe; Krapf Hilmar; Dichgans Johannes; Nägele Thomas
Diffusion-weighted MRI of spinal cord infarction--high resolution imaging and time course of diffusion abnormality.
Journal of neurology 2004;251(7):818-24.
2004: Kortmann Rolf-Dieter; Jeremic Branislav; Weller Michael; Lutterbach Johannes; Paulsen Frank; Bamberg Michael
Immediate postoperative radiotherapy or "watch and wait" in the management of adult low-grade glioma?
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2004;180(7):408-18.
2004: Herrlinger U; Wiendl H; Renninger M; Förschler H; Dichgans J; Weller M
Vascular endothelial growth factor (VEGF) in leptomeningeal metastasis: diagnostic and prognostic value.
British journal of cancer 2004;91(2):219-24.
2004: Wick W; Steinbach J P; Küker W M; Dichgans J; Bamberg M; Weller M
One week on/one week off: a novel active regimen of temozolomide for recurrent glioblastoma.
Neurology 2004;62(11):2113-5.
2004: Steinbach Joachim P; Klumpp Andrea; Wolburg Hartwig; Weller Michael
Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death.
Cancer research 2004;64(5):1575-8.
2004: Herrlinger Ulrich; Aulwurm Steffen; Strik Herwig; Weit Simone; Naumann Ulrike; Weller Michael
MIP-1alpha antagonizes the effect of a GM-CSF-enhanced subcutaneous vaccine in a mouse glioma model.
Journal of neuro-oncology 2004;66(1-2):147-54.
2004: Naumann U; Wick W; Beschorner R; Meyermann R; Weller M
Expression and functional activity of osteoprotegerin in human malignant gliomas.
Acta neuropathologica 2004;107(1):17-22.
2004: Weller Michael
[Changes in survival by combined radio-chemotherapy]
Krankenpflege Journal 2004;42(5-6):156.
2003: Friese Manuel A; Platten Michael; Lutz Stefan Z; Naumann Ulrike; Aulwurm Steffen; Bischof Felix; Bühring Hans-Jörg; Dichgans Johannes; Rammensee Hans-Georg; Steinle Alexander; Weller Michael
MICA/NKG2D-mediated immunogene therapy of experimental gliomas.
Cancer research 2003;63(24):8996-9006.
2003: Schreiner Bettina; Wischhusen Jörg; Mitsdoerffer Meike; Schneider Dagmar; Bornemann Antje; Melms Arthur; Tolosa Eva; Weller Michael; Wiendl Heinz
Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo.
Glia 2003;44(3):296-301.
2003: Wischhusen J; Naumann U; Ohgaki H; Rastinejad F; Weller M
CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death.
Oncogene 2003;22(51):8233-45.
2003: Wintterle Sabine; Schreiner Bettina; Mitsdoerffer Meike; Schneider Dagmar; Chen Lieping; Meyermann Richard; Weller Michael; Wiendl Heinz
Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis.
Cancer research 2003;63(21):7462-7.
2003: Wiendl Heinz; Mitsdoerffer Meike; Weller Michael
Express and protect yourself: the potential role of HLA-G on muscle cells and in inflammatory myopathies.
Human immunology 2003;64(11):1050-6.
2003: Weissert Robert; Wiendl Heinz; Pfrommer Heike; Storch Maria K; Schreiner Bettina; Barth Silvia; Seifert Thomas; Melms Arthur; Dichgans Johannes; Weller Michael
Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes.
Journal of neuroimmunology 2003;144(1-2):28-37.
2003: Wiendl Heinz; Mitsdoerffer Meike; Weller Michael
Hide-and-seek in the brain: a role for HLA-G mediating immune privilege for glioma cells.
Seminars in cancer biology 2003;13(5):343-51.
2003: Bähr Oliver; Rieger Johannes; Duffner Frank; Meyermann Richard; Weller Michael; Wick Wolfgang
P-glycoprotein and multidrug resistance-associated protein mediate specific patterns of multidrug resistance in malignant glioma cell lines, but not in primary glioma cells.
Brain pathology (Zurich, Switzerland) 2003;13(4):482-94.
2003: Platten Michael; Eitel Katrin; Wischhusen Jörg; Dichgans Johannes; Weller Michael
Involvement of protein kinase Cdelta and extracellular signal-regulated kinase-2 in the suppression of microglial inducible nitric oxide synthase expression by N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast).
Biochemical pharmacology 2003;66(7):1263-70.
2003: Wiendl Heinz; Mitsdoerffer Meike; Schneider Dagmar; Chen Lieping; Lochmüller Hanns; Melms Arthur; Weller Michael
Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1892-4.
2003: Platten Michael; Kretz Alexandra; Naumann Ulrike; Aulwurm Steffen; Egashira Kensuke; Isenmann Stefan; Weller Michael
Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas.
Annals of neurology 2003;54(3):388-92.
2003: Naumann Ulrike; Schmidt Friederike; Wick Wolfgang; Frank Brigitte; Weit Simone; Gillissen Bernd; Daniel Peter; Weller Michael
Adenoviral natural born killer gene therapy for malignant glioma.
Human gene therapy 2003;14(13):1235-46.
2003: Weller Michael; Müller Bettina; Koch Rainer; Bamberg Michael; Krauseneck Peter;
Neuro-Oncology Working Group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(17):3276-84.
2003: Hermisson M; Weller M
NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells.
Cell death and differentiation 2003;10(9):1078-89.
2003: Wiendl H; Feiden W; Scherieble H; Renz T; Dichgans J; Weller M
March 2003: a 41 -year-old female with a solitary lesion in the liver.
Brain pathology (Zurich, Switzerland) 2003;13(3):421-3.
2003: Wiendl Heinz; Neuhaus Oliver; Mehling Matthias; Wintterle Sabine; Schreiner Bettina; Mitsdoerffer Meike; Wienhold Wolfgang; Weissert Robert; Wessels Johannes; Hartung Hans-Peter; Weller Michael; Tolosa Eva; Melms Arthur
The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis.
Journal of neuroimmunology 2003;140(1-2):177-87.
2003: Steinbach J P; Wolburg H; Klumpp A; Probst H; Weller M
Hypoxia-induced cell death in human malignant glioma cells: energy deprivation promotes decoupling of mitochondrial cytochrome c release from caspase processing and necrotic cell death.
Cell death and differentiation 2003;10(7):823-32.
2003: Brötz D; Küker W; Maschke E; Wick W; Dichgans J; Weller M
A prospective trial of mechanical physiotherapy for lumbar disk prolapse.
Journal of neurology 2003;250(6):746-9.
2003: Rieger Johannes; Wick Wolfgang; Weller Michael
Human malignant glioma cells express semaphorins and their receptors, neuropilins and plexins.
Glia 2003;42(4):379-89.
2003: Wiendl Heinz; Mitsdoerffer Meike; Schneider Dagmar; Melms Arthur; Lochmuller Hanns; Hohlfeld Reinhard; Weller Michael
Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies.
Brain : a journal of neurology 2003;126(Pt 5):1026-35.
2003: Kortmann Rolf-Dieter; Jeremic Branislav; Weller Michael; Plasswilm Ludwig; Bamberg Michael
Radiochemotherapy of malignant glioma in adults. Clinical experiences.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2003;179(4):219-32.
2003: Grassmé H; Jendrossek V; Riehle A; von Kürthy G; Berger J; Schwarz H; Weller M; Kolesnick R; Gulbins E
Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts.
Nature medicine 2003;9(3):322-30.
2003: Waltereit Robert; Weller Michael
Signaling from cAMP/PKA to MAPK and synaptic plasticity.
Molecular neurobiology 2003;27(1):99-106.
2003: Naumann Ulrike; Waltereit Robert; Schulz Jörg B; Weller Michael
Adenoviral (full-length) Apo2L/TRAIL gene transfer is an ineffective treatment strategy for malignant glioma.
Journal of neuro-oncology 2003;61(1):7-15.
2003: Wiendl Heinz; Mitsdoerffer Meike; Hofmeister Valeska; Wischhusen Joerg; Weiss Elisabeth H; Dichgans Johannes; Lochmuller Hanns; Hohlfeld Reinhard; Melms Arthur; Weller Michael
The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy.
Brain : a journal of neurology 2003;126(Pt 1):176-85.
2002: Küker W; Herrlinger U; Grönewäller E; Rohrbach J M; Weller M
Ocular manifestation of primary nervous system lymphoma: what can be expected from imaging?
Journal of neurology 2002;249(12):1713-6.
2002: Waltereit Robert; Küker Wilhelm; Jürgens Stefan; Weller Michael; Dichgans Johannes; Wiendl Heinz
Acute transverse myelitis associated with coxiella burnetii infection.
Journal of neurology 2002;249(10):1459-61.
2002: Waltereit Robert; Weller Michael
The role of caspases 9 and 9-short (9S) in death ligand- and drug-induced apoptosis in human astrocytoma cells.
Brain research. Molecular brain research 2002;106(1-2):42-9.
2002: Schmidt Friederike; Faul Christoph; Dichgans Johannes; Weller Michael
Low molecular weight heparin for deep vein thrombosis in glioma patients.
Journal of neurology 2002;249(10):1409-12.
2002: Herrlinger Ulrich; Felsberg Jörg; Küker Wilhelm; Bornemann Antje; Plasswilm Ludwig; Knobbe Christiane B; Strik Herwig; Wick Wolfgang; Meyermann Richard; Dichgans Johannes; Bamberg Michael; Reifenberger Guido; Weller Michael
Gliomatosis cerebri: molecular pathology and clinical course.
Annals of neurology 2002;52(4):390-9.
2002: Wick Wolfgang; Hermisson Mirjam; Kortmann Rolf D; Küker Wilhelm M; Duffner Frank; Dichgans Johannes; Bamberg Michael; Weller Michael
Neoadjuvant gemcitabine/treosulfan chemotherapy for newly diagnosed glioblastoma: a phase II study.
Journal of neuro-oncology 2002;59(2):151-5.
2002: Reichert Manuela; Steinbach Joachim P; Supra Petra; Weller Michael
Modulation of growth and radiochemosensitivity of human malignant glioma cells by acidosis.
Cancer 2002;95(5):1113-9.
2002: Plasswilm L; Herrlinger U; Korfel A; Weller M; Küker W; Kanz L; Thiel E; Bamberg M
Primary central nervous system (CNS) lymphoma in immunocompetent patients.
Annals of hematology 2002;81(8):415-23.
2002: Hipp Mark S; Urbich Carmen; Mayer Petra; Wischhusen Jörg; Weller Michael; Kracht Michael; Spyridopoulos Ioakim
Proteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1.
European journal of immunology 2002;32(8):2208-17.
2002: Wick Antje; Wick Wolfgang; Waltenberger Johannes; Weller Michael; Dichgans Johannes; Schulz Jörg B
Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(15):6401-7.
2002: Wick W; Stock J; Seyfried J; Baumgart J; Wüllner U; Weller M
CD95/CD95 ligand-independent potentiation of treosulfan cytotoxicity by BSO in malignant glioma cells in vitro and in vivo.
International journal of oncology 2002;21(1):213-20.
2002: Hermisson M; Klein R; Schmidt F; Weller M; Küker W
Myelopathy in primary Sjögren's syndrome: diagnostic and therapeutic aspects.
Acta neurologica Scandinavica 2002;105(6):450-3.
2002: Herrlinger U; Küker W; Platten M; Dichgans J; Weller M
First-line therapy with temozolomide induces regression of primary CNS lymphoma.
Neurology 2002;58(10):1573-4.
2002: Von Pfeil A; Hakenjos L; Herskind C; Dittmann K; Weller M; Rodemann H P
Irradiated homozygous TGF-beta1 knockout fibroblasts show enhanced clonogenic survival as compared with TGF-beta1 wild-type fibroblasts.
International journal of radiation biology 2002;78(5):331-9.
2002: Wischhusen Jörg; Jung Gundram; Radovanovic Ivan; Beier Christoph; Steinbach Joachim P; Rimner Andreas; Huang Huatao; Schulz Jörg B; Ohgaki Hiroko; Aguzzi Adriano; Rammensee Hans-Georg; Weller Michael
Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma.
Cancer research 2002;62(9):2592-9.
2002: Wiendl Heinz; Mitsdoerffer Meike; Hofmeister Valeska; Wischhusen Jörg; Bornemann Antje; Meyermann Richard; Weiss Elisabeth H; Melms Arthur; Weller Michael
A functional role of HLA-G expression in human gliomas: an alternative strategy of immune escape.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4772-80.
2002: Steinbach Joachim P; Weller Michael
Mechanisms of apoptosis in central nervous system tumors: application to theory.
Current neurology and neuroscience reports 2002;2(3):246-53.
2002: Gleichmann M; Buchheim G; El-Bizri H; Yokota Y; Klockgether T; Kügler S; Bähr M; Weller M; Schulz J B
Identification of inhibitor-of-differentiation 2 (Id2) as a modulator of neuronal apoptosis.
Journal of neurochemistry 2002;80(5):755-62.
2002: Wick Wolfgang; Wick Antje; Schulz Jörg B; Dichgans Johannes; Rodemann Hans P; Weller Michael
Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase.
Cancer research 2002;62(6):1915-9.
2002: Herrlinger Ulrich; Schabet Martin; Brugger Wolfram; Kortmann Rolf-Dieter; Küker Wilhelm; Deckert Martina; Engel Corinna; Schmeck-Lindenau Hans-Jürgen; Mergenthaler Hans-Günther; Krauseneck Peter; Benöhr Christian; Meisner Christoph; Wiestler Otmar D; Dichgans Johannes; Kanz Lothar; Bamberg Michael; Weller Michael
German Cancer Society Neuro-Oncology Working Group NOA-03 multicenter trial of single-agent high-dose methotrexate for primary central nervous system lymphoma.
Annals of neurology 2002;51(2):247-52.
2002: Streffer Johannes R; Rimner Andreas; Rieger Johannes; Naumann Ulrike; Rodemann Hans-Peter; Weller Michael
BCL-2 family proteins modulate radiosensitivity in human malignant glioma cells.
Journal of neuro-oncology 2002;56(1):43-9.
2002: Steinbach Joachim P; Supra Petra; Huang H-J Su; Cavenee Webster K; Weller Michael
CD95-mediated apoptosis of human glioma cells: modulation by epidermal growth factor receptor activity.
Brain pathology (Zurich, Switzerland) 2002;12(1):12-20.
2001: Platten M; Wick W; Wischhusen J; Weller M
N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) suppresses microglial inducible nitric oxide synthase (iNOS) expression and activity induced by interferon-gamma (IFN-gamma).
British journal of pharmacology 2001;134(6):1279-84.
2001: Rimner A; Wischhusen J; Naumann U; Gleichmann M; Steinbach J P; Weller M
Identification by suppression subtractive hybridization of p21 as a radio-inducible gene in human glioma cells.
Anticancer research 2001;21(5):3505-8.
2001: Naumann U; Weit S; Wischhusen J; Weller M
Diva/Boo is a negative regulator of cell death in human glioma cells.
FEBS letters 2001;505(1):23-6.
2001: Glaser T; Wagenknecht B; Weller M
Identification of p21 as a target of cycloheximide-mediated facilitation of CD95-mediated apoptosis in human malignant glioma cells.
Oncogene 2001;20(35):4757-67.
2001: Bühring U; Herrlinger U; Krings T; Thiex R; Weller M; Küker W
MRI features of primary central nervous system lymphomas at presentation.
Neurology 2001;57(3):393-6.
2001: Xia X G; Harding T; Weller M; Bieneman A; Uney J B; Schulz J B
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10433-8.
2001: Naumann U; Kügler S; Wolburg H; Wick W; Rascher G; Schulz J B; Conseiller E; Bähr M; Weller M
Chimeric tumor suppressor 1, a p53-derived chimeric tumor suppressor gene, kills p53 mutant and p53 wild-type glioma cells in synergy with irradiation and CD95 ligand.
Cancer research 2001;61(15):5833-42.
2001: Röhn T A; Wagenknecht B; Roth W; Naumann U; Gulbins E; Krammer P H; Walczak H; Weller M
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release.
Oncogene 2001;20(31):4128-37.
2001: Platten M; Wild-Bode C; Wick W; Leitlein J; Dichgans J; Weller M
N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) inhibits transforming growth factor-beta relesase and reduces migration and invasiveness of human malignant glioma cells.
International journal of cancer. Journal international du cancer 2001;93(1):53-61.
2001: Wick W; Platten M; Weller M
Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta.
Journal of neuro-oncology 2001;53(2):177-85.
2001: Wagenknecht B; Roth W; Gulbins E; Wolburg H; Weller M
C2-ceramide signaling in glioma cells: synergistic enhancement of CD95-mediated, caspase-dependent apoptosis.
Cell death and differentiation 2001;8(6):595-602.
2001: Wild-Bode C; Weller M; Wick W
Molecular determinants of glioma cell migration and invasion.
Journal of neurosurgery 2001;94(6):978-84.
2001: Leitlein J; Aulwurm S; Waltereit R; Naumann U; Wagenknecht B; Garten W; Weller M; Platten M
Processing of immunosuppressive pro-TGF-beta 1,2 by human glioblastoma cells involves cytoplasmic and secreted furin-like proteases.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7238-43.
2001: Streffer J R; Bitzer M; Schabet M; Dichgans J; Weller M
Response of radiochemotherapy-associated cerebral edema to a phytotherapeutic agent, H15.
Neurology 2001;56(9):1219-21.
2001: Wick W; Grimmel C; Wild-Bode C; Platten M; Arpin M; Weller M
Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(10):3360-8.
2001: Roth W; Wagenknecht B; Klumpp A; Naumann U; Hahne M; Tschopp J; Weller M
APRIL, a new member of the tumor necrosis factor family, modulates death ligand-induced apoptosis.
Cell death and differentiation 2001;8(4):403-10.
2001: Gerhardt E; Kügler S; Leist M; Beier C; Berliocchi L; Volbracht C; Weller M; Bähr M; Nicotera P; Schulz J B
Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis.
Molecular and cellular neurosciences 2001;17(4):717-31.
2001: von Coelln R; Kügler S; Bähr M; Weller M; Dichgans J; Schulz J B
Rescue from death but not from functional impairment: caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals.
Journal of neurochemistry 2001;77(1):263-73.
2001: Glaser T; Castro M G; Löwenstein P R; Weller M
Death receptor-independent cytochrome c release and caspase activation mediate thymidine kinase plus ganciclovir-mediated cytotoxicity in LN-18 and LN-229 human malignant glioma cells.
Gene therapy 2001;8(6):469-76.
2001: Schmidt F; Groscurth P; Kermer M; Dichgans J; Weller M
Lovastatin and phenylacetate induce apoptosis, but not differentiation, in human malignant glioma cells.
Acta neuropathologica 2001;101(3):217-24.
2001: Roth W; Isenmann S; Nakamura M; Platten M; Wick W; Kleihues P; Bähr M; Ohgaki H; Ashkenazi A; Weller M
Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis.
Cancer research 2001;61(6):2759-65.
2001: Wild-Bode C; Weller M; Rimner A; Dichgans J; Wick W
Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma.
Cancer research 2001;61(6):2744-50.
2001: Bähr O; Wick W; Weller M
Modulation of MDR/MRP by wild-type and mutant p53.
The Journal of clinical investigation 2001;107(5):643-6.
2001: Glaser T; Weller M
Caspase-dependent chemotherapy-induced death of glioma cells requires mitochondrial cytochrome c release.
Biochemical and biophysical research communications 2001;281(2):322-7.
2001: Isenmann S; Engel S; Kügler S; Gravel C; Weller M; Bähr M
Intravitreal adenoviral gene transfer evokes an immune response in the retina that is directed against the heterologous lacZ transgene product but does not limit transgene expression.
Brain research 2001;892(2):229-40.
2001: Platten M; Wick W; Weller M
Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape.
Microscopy research and technique 2001;52(4):401-10.
2001: Weller M; Streffer J; Wick W; Kortmann R D; Heiss E; Küker W; Meyermann R; Dichgans J; Bamberg M
Preirradiation gemcitabine chemotherapy for newly diagnosed glioblastoma. A phase II study.
Cancer 2001;91(2):423-7.
2001: Schmidt F; Rieger J; Wischhusen J; Naumann U; Weller M
Glioma cell sensitivity to topotecan: the role of p53 and topotecan-induced DNA damage.
European journal of pharmacology 2001;412(1):21-5.
2001: Herrlinger U; Schabet M; Brugger W; Kortmann R D; Kanz L; Bamberg M; Dichgans J; Weller M
Primary central nervous system lymphoma 1991-1997: outcome and late adverse effects after combined modality treatment.
Cancer 2001;91(1):130-5.
2001: Küker W; Schmidt F; Friese S; Block F; Weller M
Unilateral thalamic edema in internal cerebral venous thrombosis: is it mostly left?
Cerebrovascular diseases (Basel, Switzerland) 2001;12(4):341-5.
2000: Eberhardt O; Coelln R V; Kugler S; Lindenau J; Rathke-Hartlieb S; Gerhardt E; Haid S; Isenmann S; Gravel C; Srinivasan A; Bahr M; Weller M; Dichgans J; Schulz J B
Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(24):9126-34.
2000: Wagenknecht B; Hermisson M; Groscurth P; Liston P; Krammer P H; Weller M
Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release.
Journal of neurochemistry 2000;75(6):2288-97.
2000: Strik H M; Weller M; Frank B; Hermisson M; Deininger M H; Dichgans J; Meyermann R
Heat shock protein expression in human gliomas.
Anticancer research 2000;20(6B):4457-62.
2000: Winter S; Strik H; Rieger J; Beck J; Meyermann R; Weller M
Glutathione S-transferase and drug sensitivity in malignant glioma.
Journal of the neurological sciences 2000;179(S 1-2):115-21.
2000: Vietor M; Winter S; Groscurth P; Naumann U; Weller M
On the significance of telomerase activity in human malignant glioma cells.
European journal of pharmacology 2000;407(1-2):27-37.
2000: Grassmé H; Kirschnek S; Riethmueller J; Riehle A; von Kürthy G; Lang F; Weller M; Gulbins E
CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa.
Science (New York, N.Y.) 2000;290(5491):527-30.
2000: Schmidt F; Wick W; Herrlinger U; Dichgans J; Weller M
Treosulfan chemotherapy for recurrent malignant glioma.
Journal of neuro-oncology 2000;49(3):231-4.
2000: Kirschnek S; Paris F; Weller M; Grassme H; Ferlinz K; Riehle A; Fuks Z; Kolesnick R; Gulbins E
CD95-mediated apoptosis in vivo involves acid sphingomyelinase.
The Journal of biological chemistry 2000;275(35):27316-23.
2000: Roth W; Wild-Bode C; Platten M; Grimmel C; Melkonyan H S; Dichgans J; Weller M
Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells.
Oncogene 2000;19(37):4210-20.
2000: Herrlinger U; Klingel K; Meyermann R; Kandolf R; Kaiserling E; Kortmann R D; Melms A; Skalej M; Dichgans J; Weller M
Central nervous system Hodgkin's lymphoma without systemic manifestation: case report and review of the literature.
Acta neuropathologica 2000;99(6):709-14.
2000: Winter S; Weller M
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
European journal of pharmacology 2000;398(2):177-83.
2000: Hermisson M; Weller M
Hyperthermia enhanced chemosensitivity of human malignant glioma cells.
Anticancer research 2000;20(3A):1819-23.
2000: Hermisson M; Wagenknecht B; Wolburg H; Glaser T; Dichgans J; Weller M
Sensitization to CD95 ligand-induced apoptosis in human glioma cells by hyperthermia involves enhanced cytochrome c release.
Oncogene 2000;19(19):2338-45.
2000: Rieger L; Rieger J; Winter S; Streffer J; Esser P; Dichgans J; Meyermann R; Weller M
Evidence for a constitutive, verapamil-sensitive, non-P-glycoprotein multidrug resistance phenotype in malignant glioma that is unaltered by radiochemotherapy in vivo.
Acta neuropathologica 2000;99(5):555-62.
2000: Streffer J; Schabet M; Bamberg M; Grote E H; Meyermann R; Voigt K; Dichgans J; Weller M
A role for preirradiation PCV chemotherapy for oligodendroglial brain tumors.
Journal of neurology 2000;247(4):297-302.
2000: Roth W; Grimmel C; Rieger L; Strik H; Takayama S; Krajewski S; Meyermann R; Dichgans J; Reed J C; Weller M
Bag-1 and Bcl-2 gene transfer in malignant glioma: modulation of cell cycle regulation and apoptosis.
Brain pathology (Zurich, Switzerland) 2000;10(2):223-34.
2000: Herrlinger U; Brugger W; Bamberg M; Küker W; Dichgans J; Weller M
PCV salvage chemotherapy for recurrent primary CNS lymphoma.
Neurology 2000;54(8):1707-8.
2000: Hermisson M; Strik H; Rieger J; Dichgans J; Meyermann R; Weller M
Expression and functional activity of heat shock proteins in human glioblastoma multiforme.
Neurology 2000;54(6):1357-65.
2000: Gleichmann M; Weller M; Schulz J B
Insulin-like growth factor-1-mediated protection from neuronal apoptosis is linked to phosphorylation of the pro-apoptotic protein BAD but not to inhibition of cytochrome c translocation in rat cerebellar neurons.
Neuroscience letters 2000;282(1-2):69-72.
2000: Platten M; Wick W; Wild-Bode C; Aulwurm S; Dichgans J; Weller M
Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via Up-regulation of alpha(V)beta(3) integrin expression.
Biochemical and biophysical research communications 2000;268(2):607-11.
2000: Schmidt F; Groscurth P; Dichgans J; Weller M
Human malignant glioma cell lines are refractory to retinoic acid-mediated differentiation and sensitization to apoptosis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(3):159-68.
1999: Bartussek C; Naumann U; Weller M
Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status.
Experimental cell research 1999;253(2):432-9.
1999: Strik H; Deininger M; Streffer J; Grote E; Wickboldt J; Dichgans J; Weller M; Meyermann R
BCL-2 family protein expression in initial and recurrent glioblastomas: modulation by radiochemotherapy.
Journal of neurology, neurosurgery, and psychiatry 1999;67(6):763-8.
1999: Streffer J R; Schuster M; Pohl U; Belka C; Dichgans J; Bamberg M; Weller M
Irradiation induced clonogenic cell death of human malignant glioma cells does not require CD95/CD95L interactions.
Anticancer research 1999;19(6B):5265-9.
1999: Lepple-Wienhues A; Belka C; Laun T; Jekle A; Walter B; Wieland U; Welz M; Heil L; Kun J; Busch G; Weller M; Bamberg M; Gulbins E; Lang F
Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13795-800.
1999: Roth W; Isenmann S; Naumann U; Kügler S; Bähr M; Dichgans J; Ashkenazi A; Weller M
Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.
Biochemical and biophysical research communications 1999;265(2):479-83.
1999: Deininger M H; Weller M; Streffer J; Meyermann R
Antiapoptotic Bcl-2 family protein expression increases with progression of oligodendroglioma.
Cancer 1999;86(9):1832-9.
1999: Roth W; Weller M
Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives.
Cellular and molecular life sciences : CMLS 1999;56(5-6):481-506.
1999: Weller M; List U; Schabet M; Melms A; Dichgans J
Elevated CSF lactoferrin in superficial siderosis of the central nervous system.
Journal of neurology 1999;246(10):943-5.
1999: Pohl U; Wick W; Weissenberger J; Steinbach J P; Dichgans J; Aguzzi A; Weller M
Characterization of Tu-2449, a glioma cell line derived from a spontaneous tumor in GFAP-v-src-transgenic mice: comparison with established murine glioma cell lines.
International journal of oncology 1999;15(4):829-34.
1999: Klöcker N; Kermer P; Gleichmann M; Weller M; Bähr M
Both the neuronal and inducible isoforms contribute to upregulation of retinal nitric oxide synthase activity by brain-derived neurotrophic factor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(19):8517-27.
1999: Engel S; Isenmann S; Ständer M; Rieger J; Bähr M; Weller M
Inhibition of experimental rat glioma growth by decorin gene transfer is associated with decreased microglial infiltration.
Journal of neuroimmunology 1999;99(1):13-8.
1999: Glaser T; Wagenknecht B; Groscurth P; Krammer P H; Weller M
Death ligand/receptor-independent caspase activation mediates drug-induced cytotoxic cell death in human malignant glioma cells.
Oncogene 1999;18(36):5044-53.
1999: Deininger M H; Weller M; Streffer J; Mittelbronn M; Meyermann R
Patterns of cyclooxygenase-1 and -2 expression in human gliomas in vivo.
Acta neuropathologica 1999;98(3):240-4.
1999: Naumann U; Weit S; Rieger L; Meyermann R; Weller M
p27 modulates cell cycle progression and chemosensitivity in human malignant glioma.
Biochemical and biophysical research communications 1999;261(3):890-6.
1999: Weller M
Glucocorticoid treatment of primary CNS lymphoma.
Journal of neuro-oncology 1999;43(3):237-9.
1999: Wick W; Furnari F B; Naumann U; Cavenee W K; Weller M
PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.
Oncogene 1999;18(27):3936-43.
1999: Eitel K; Wagenknecht B; Weller M
Inhibition of drug-induced DNA fragmentation, but not cell death, of glioma cells by non-caspase protease inhibitors.
Cancer letters 1999;142(1):11-6.
1999: Soldner F; Weller M; Haid S; Beinroth S; Miller S W; Wüllner U; Davis R E; Dichgans J; Klockgether T; Schulz J B
MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1).
Experimental cell research 1999;250(1):75-85.
1999: Roller A; Bähr O R; Streffer J; Winter S; Heneka M; Deininger M; Meyermann R; Naumann U; Gulbins E; Weller M
Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: the role of COX-1 and MRP.
Biochemical and biophysical research communications 1999;259(3):600-5.
1999: Wick W; Grimmel C; Wagenknecht B; Dichgans J; Weller M
Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for new protein synthesis, formation of reactive oxygen species, and caspase processing.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1306-12.
1999: Ständer M; Naumann U; Wick W; Weller M
Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.
Cell and tissue research 1999;296(2):221-7.
1999: Glaser T; Winter S; Groscurth P; Safayhi H; Sailer E R; Ammon H P; Schabet M; Weller M
Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity.
British journal of cancer 1999;80(5-6):756-65.
1999: Wüllner U; Seyfried J; Groscurth P; Beinroth S; Winter S; Gleichmann M; Heneka M; Löschmann P; Schulz J B; Weller M; Klockgether T
Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function.
Brain research 1999;826(1):53-62.
1999: Schulz J B; Weller M; Moskowitz M A
Caspases as treatment targets in stroke and neurodegenerative diseases.
Annals of neurology 1999;45(4):421-9.
1999: Schmidt F; Schuster M; Streffer J; Schabet M; Weller M
Topotecan-based combination chemotherapy for human malignant glioma.
Anticancer research 1999;19(2A):1217-21.
1999: Münz C; Naumann U; Grimmel C; Rammensee H G; Weller M
TGF-beta-independent induction of immunogenicity by decorin gene transfer in human malignant glioma cells.
European journal of immunology 1999;29(3):1032-40.
1999: Abele M; Weller M; Mescheriakov S; Bürk K; Dichgans J; Klockgether T
Cerebellar ataxia with glutamic acid decarboxylase autoantibodies.
Neurology 1999;52(4):857-9.
1999: Rieger J; Durka S; Streffer J; Dichgans J; Weller M
Gemcitabine cytotoxicity of human malignant glioma cells: modulation by antioxidants, BCL-2 and dexamethasone.
European journal of pharmacology 1999;365(2-3):301-8.
1999: Rieger J; Ohgaki H; Kleihues P; Weller M
Human astrocytic brain tumors express AP02L/TRAIL.
Acta neuropathologica 1999;97(1):1-4.
1999: Simons M; Beinroth S; Gleichmann M; Liston P; Korneluk R G; MacKenzie A E; Bähr M; Klockgether T; Robertson G S; Weller M; Schulz J B
Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.
Journal of neurochemistry 1999;72(1):292-301.
1999: Wagenknecht B; Hermisson M; Eitel K; Weller M
Proteasome inhibitors induce p53/p21-independent apoptosis in human glioma cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1999;9(3):117-25.
1999: Borbé R; Rieger J; Weller M
Failure of taxol-based combination chemotherapy for malignant glioma cannot be overcome by G2/M checkpoint abrogators or altering the p53 status.
Cancer chemotherapy and pharmacology 1999;44(3):217-27.
1999: Pohl U; Wagenknecht B; Naumann U; Weller M
p53 enhances BAK and CD95 expression in human malignant glioma cells but does not enhance CD95L-induced apoptosis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1999;9(1):29-37.
1998: Streffer J R; Schuster M; Zipp F; Weller M
Soluble CD95 (Fas/APO-1) in malignant glioma: (no) implications for CD95-based immunotherapy?
Journal of neuro-oncology 1998;40(3):233-5.
1998: Wick W; Wagner S; Kerkau S; Dichgans J; Tonn J C; Weller M
BCL-2 promotes migration and invasiveness of human glioma cells.
FEBS letters 1998;440(3):419-24.
1998: Weller M; Rieger J; Grimmel C; Van Meir E G; De Tribolet N; Krajewski S; Reed J C; von Deimling A; Dichgans J
Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses.
International journal of cancer. Journal international du cancer 1998;79(6):640-4.
1998: Roller A; Weller M
Antioxidants specifically inhibit cisplatin cytotoxicity of human malignant glioma cells.
Anticancer research 1998;18(6A):4493-7.
1998: Rieger J; Ständer M; Löschmann P A; Heneka M; Dichgans J; Klockgether T; Weller M
Synthesis and biological effects of NO in malignant glioma cells: modulation by cytokines including CD95L and TGF-beta, dexamethasone, and p53 gene transfer.
Oncogene 1998;17(18):2323-32.
1998: Wagenknecht B; Schulz J B; Gulbins E; Weller M
Crm-A, bcl-2 and NDGA inhibit CD95L-induced apoptosis of malignant glioma cells at the level of caspase 8 processing.
Cell death and differentiation 1998;5(10):894-900.
1998: Schulz J B; Weller M; Matthews R T; Heneka M T; Groscurth P; Martinou J C; Lommatzsch J; von Coelln R; Wüllner U; Löschmann P A; Beal M F; Dichgans J; Klockgether T
Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.
Cell death and differentiation 1998;5(10):847-57.
1998: Ständer M; Naumann U; Dumitrescu L; Heneka M; Löschmann P; Gulbins E; Dichgans J; Weller M
Decorin gene transfer-mediated suppression of TGF-beta synthesis abrogates experimental malignant glioma growth in vivo.
Gene therapy 1998;5(9):1187-94.
1998: Naumann U; Durka S; Weller M
Dexamethasone-mediated protection from drug cytotoxicity: association with p21WAF1/CIP1 protein accumulation?
Oncogene 1998;17(12):1567-75.
1998: Wüllner U; Weller M; Schulz J B; Krajewski S; Reed J C; Klockgether T
Bcl-2, Bax and Bcl-x expression in neuronal apoptosis: a study of mutant weaver and lurcher mice.
Acta neuropathologica 1998;96(3):233-8.
1998: Winter S; Weller M
Potentiation of CD95L-induced apoptosis of human malignant glioma cells by topotecan involves inhibition of RNA synthesis but not changes in CD95 or CD95L protein expression.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1374-82.
1998: Trepel M; Groscurth P; Malipiero U; Gulbins E; Dichgans J; Weller M
Chemosensitivity of human malignant glioma: modulation by p53 gene transfer.
Journal of neuro-oncology 1998;39(1):19-32.
1998: Hueber A; Durka S; Weller M
CD95-mediated apoptosis: no variation in cellular sensitivity during cell cycle progression.
FEBS letters 1998;432(3):155-7.
1998: Hueber A; Winter S; Weller M
Chemotherapy primes malignant glioma cells for CD95 ligand-induced apoptosis up-stream of caspase 3 activation.
European journal of pharmacology 1998;352(1):111-5.
1998: Roth W; Wagenknecht B; Dichgans J; Weller M
Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells.
Journal of neuroimmunology 1998;87(1-2):121-9.
1998: Heneka M T; Löschmann P A; Gleichmann M; Weller M; Schulz J B; Wüllner U; Klockgether T
Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide.
Journal of neurochemistry 1998;71(1):88-94.
1998: Herrlinger U; Weller M; Schabet M
New aspects of immunotherapy of leptomeningeal metastasis.
Journal of neuro-oncology 1998;38(2-3):233-9.
1998: Weller M; Schuster M; Pietsch T; Schabet M
CD95 ligand-induced apoptosis of human medulloblastoma cells.
Cancer letters 1998;128(2):121-6.
1998: Zipp F; Otzelberger K; Dichgans J; Martin R; Weller M
Serum CD95 of relapsing remitting multiple sclerosis patients protects from CD95-mediated apoptosis.
Journal of neuroimmunology 1998;86(2):151-4.
1998: Weller M
Predicting response to cancer chemotherapy: the role of p53.
Cell and tissue research 1998;292(3):435-45.
1998: Rieger J; Naumann U; Glaser T; Ashkenazi A; Weller M
APO2 ligand: a novel lethal weapon against malignant glioma?
FEBS letters 1998;427(1):124-8.
1998: Weller M; Dichgans J; Klockgether T
Acetazolamide-responsive migraine in CADASIL.
Neurology 1998;50(5):1505.
1998: Ständer M; Dichgans J; Weller M
Anticonvulsant drugs fail to modulate chemotherapy-induced cytotoxicity and growth inhibition of human malignant glioma cells.
Journal of neuro-oncology 1998;37(3):191-8.
1998: Weller M; Kleihues P; Dichgans J; Ohgaki H
CD95 ligand: lethal weapon against malignant glioma?
Brain pathology (Zurich, Switzerland) 1998;8(2):285-93.
1998: Schulz J B; Beinroth S; Weller M; Wüllner U; Klockgether T
Endonucleolytic DNA fragmentation is not required for apoptosis of cultured rat cerebellar granule neurons.
Neuroscience letters 1998;245(1):9-12.
1998: Weller M; Bornemann A; Ständer M; Schabet M; Dichgans J; Meyermann R
Humoral immune response to p53 in malignant glioma.
Journal of neurology 1998;245(3):169-72.
1998: Gulbins E; Hermisson M; Brenner B; Grassmé H U; Linderkamp O; Dichgans J; Weller M; Lang F
Cellular stimulation via CD95 involves activation of phospho-inositide-3-kinase.
Pflügers Archiv : European journal of physiology 1998;435(4):546-54.
1998: Rieger L; Weller M; Bornemann A; Schabet M; Dichgans J; Meyermann R
BCL-2 family protein expression in human malignant glioma: a clinical-pathological correlative study.
Journal of the neurological sciences 1998;155(1):68-75.
1998: Reber U; Wüllner U; Trepel M; Baumgart J; Seyfried J; Klockgether T; Dichgans J; Weller M
Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2.
Biochemical pharmacology 1998;55(3):349-59.
1998: Brenner B; Ferlinz K; Grassmé H; Weller M; Koppenhoefer U; Dichgans J; Sandhoff K; Lang F; Gulbins E
Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases.
Cell death and differentiation 1998;5(1):29-37.
1998: Winter S; Roth W; Dichgans J; Weller M
Synergy of CD95 ligand and teniposide: no role of cleavable complex formation and enhanced CD95 expression.
European journal of pharmacology 1998;341(2-3):323-8.
1998: Zipp F; Faber E; Sommer N; Müller C; Dichgans J; Krammer P H; Martin R; Weller M
CD95 expression and CD95-mediated apoptosis of T cells in multiple sclerosis. No differences from normal individuals and no relation to HLA-DR2.
Journal of neuroimmunology 1998;81(1-2):168-72.
1998: Zipp F; Weller M; Calabresi P A; Frank J A; Bash C N; Dichgans J; McFarland H F; Martin R
Increased serum levels of soluble CD95 (APO-1/Fas) in relapsing-remitting multiple sclerosis.
Annals of neurology 1998;43(1):116-20.
1998: Gleichmann M; Beinroth S; Reed J C; Krajewski S; Schulz J B; Wüllner U; Klockgether T; Weller M
Potassium deprivation-induced apoptosis of cerebellar granule neurons: cytochrome c release in the absence of altered expression of Bcl-2 family proteins.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 1998;8(4):194-201.
1998: Roth W; Wagenknecht B; Grimmel C; Dichgans J; Weller M
Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells: association with bcl-2 phosphorylation but neither activation of p53 nor G2/M cell cycle arrest.
British journal of cancer 1998;77(3):404-11.
1997: Wüllner U; Weller M; Groscurth P; Löschmann P A; Schulz J B; Müller I; Klockgether T
Evidence for an active type of cell death with ultrastructural features distinct from apoptosis: the effects of 3-acetylpyridine neurotoxicity.
Neuroscience 1997;81(3):721-34.
1997: Weller M; Winter S; Schmidt C; Esser P; Fontana A; Dichgans J; Groscurth P
Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone.
International journal of cancer. Journal international du cancer 1997;73(5):707-14.
1997: Trepel M; Scheding S; Groscurth P; Horny H P; Malipiero U; Brugger W; Dichgans J; Weller M
A new look at the role of p53 in leukemia cell sensitivity to chemotherapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(11):1842-9.
1997: Schulz J B; Bremen D; Reed J C; Lommatzsch J; Takayama S; Wüllner U; Löschmann P A; Klockgether T; Weller M
Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: prevention of caspase activation and reduced production of reactive oxygen species.
Journal of neurochemistry 1997;69(5):2075-86.
1997: Weller M; Trepel M; Grimmel C; Schabet M; Bremen D; Krajewski S; Reed J C
Hypericin-induced apoptosis of human malignant glioma cells is light-dependent, independent of bcl-2 expression, and does not require wild-type p53.
Neurological research 1997;19(5):459-70.
1997: Zipp F; Martin R; Lichtenfels R; Roth W; Dichgans J; Krammer P H; Weller M
Human autoreactive and foreign antigen-specific T cells resist apoptosis induced by soluble recombinant CD95 ligand.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2108-15.
1997: Wagenknecht B; Gulbins E; Lang F; Dichgans J; Weller M
Lipoxygenase inhibitors block CD95 ligand-mediated apoptosis of human malignant glioma cells.
FEBS letters 1997;409(1):17-23.
1997: Weller M; Schmidt C; Roth W; Dichgans J
Chemotherapy of human malignant glioma: prevention of efficacy by dexamethasone?
Neurology 1997;48(6):1704-9.
1997: Roth W; Fontana A; Trepel M; Reed J C; Dichgans J; Weller M
Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics.
Cancer immunology, immunotherapy : CII 1997;44(1):55-63.
1997: Sommer N; Sigg B; Melms A; Weller M; Schepelmann K; Herzau V; Dichgans J
Ocular myasthenia gravis: response to long-term immunosuppressive treatment.
Journal of neurology, neurosurgery, and psychiatry 1997;62(2):156-62.
1997: Klockgether T; Weller M; Haarmeier T; Kaskas B; Maier G; Dichgans J
Gluteal compartment syndrome due to rhabdomyolysis after heroin abuse.
Neurology 1997;48(1):275-6.
1997: Weller M; Schulz J B; Wüllner U; Löschmann P A; Klockgether T; Dichgans J
Developmental and genetic regulation of programmed neuronal death.
Journal of neural transmission. Supplementum 1997;50():115-23.

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