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Robert Wells

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Escherichia coli

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Co-Publications
Name
20
Bacolla, Albino
16
Jaworski, Adam
10
Larson, Jacquelynn
10
Napierala, Marek
7
Iyer, Ravi
7
Parniewski, Pawel
5
Pluciennik, Anna
5
Jakupciak, John
4
Montermini, L
4
Bowater, Richard
4
Cooper, David
4
Dere, Ruhee
4
Pandolfo, Massimo
4
Rosche, William
4
Sinden, Richard

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Publications

TOP 3
Chuzhanova Nadia; Chen Jian-Min; Bacolla Albino; Patrinos George P; Férec Claude; Wells Robert D; Cooper David N
Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repair.
Bacolla Albino; Wells Robert D
Non-B DNA conformations as determinants of mutagenesis and human disease.
Wells Robert D
Discovery of the role of non-B DNA structures in mutagenesis and human genomic disorders.

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All Publications

2009: Chuzhanova Nadia; Chen Jian-Min; Bacolla Albino; Patrinos George P; Férec Claude; Wells Robert D; Cooper David N
Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repair.
Human mutation 2009;30(8):1189-98.
2009: Bacolla Albino; Wells Robert D
Non-B DNA conformations as determinants of mutagenesis and human disease.
Molecular carcinogenesis 2009;48(4):273-85.
2009: Wells Robert D
Discovery of the role of non-B DNA structures in mutagenesis and human genomic disorders.
The Journal of biological chemistry 2009;284(14):8997-9009.
2009: Wells Robert D
Mutation spectra in fragile X syndrome induced by deletions of CGG*CCG repeats.
The Journal of biological chemistry 2009;284(12):7407-11.
2008: Soragni E; Herman D; Dent S Y R; Gottesfeld J M; Wells R D; Napierala M
Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia.
Nucleic acids research 2008;36(19):6056-65.
2008: Bacolla Albino; Larson Jacquelynn E; Collins Jack R; Li Jian; Milosavljevic Aleksandar; Stenson Peter D; Cooper David N; Wells Robert D
Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties.
Genome research 2008;18(10):1545-53.
2008: Wells Robert D
DNA triplexes and Friedreich ataxia.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(6):1625-34.
2007: Kosmider Beata; Wells Robert D
Fragile X repeats are potent inducers of complex, multiple site rearrangements in flanking sequences in Escherichia coli.
DNA repair 2007;6(12):1850-63.
2007: Wells Robert D
Non-B DNA conformations, mutagenesis and disease.
Trends in biochemical sciences 2007;32(6):271-8.
2006: Bacolla Albino; Wojciechowska Marzena; Kosmider Beata; Larson Jacquelynn E; Wells Robert D
The involvement of non-B DNA structures in gross chromosomal rearrangements.
DNA repair 2006;5(9-10):1161-70.
2006: Burnett Ryan; Melander Christian; Puckett James W; Son Leslie S; Wells Robert D; Dervan Peter B; Gottesfeld Joel M
DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11497-502.
2006: Wojciechowska Marzena; Napierala Marek; Larson Jacquelynn E; Wells Robert D
Non-B DNA conformations formed by long repeating tracts of myotonic dystrophy type 1, myotonic dystrophy type 2, and Friedreich's ataxia genes, not the sequences per se, promote mutagenesis in flanking regions.
The Journal of biological chemistry 2006;281(34):24531-43.
2006: Son Leslie S; Bacolla Albino; Wells Robert D
Sticky DNA: in vivo formation in E. coli and in vitro association of long GAA*TTC tracts to generate two independent supercoiled domains.
Journal of molecular biology 2006;360(2):267-84.
2006: Dere Ruhee; Wells Robert D
DM2 CCTG*CAGG repeats are crossover hotspots that are more prone to expansions than the DM1 CTG*CAG repeats in Escherichia coli.
Journal of molecular biology 2006;360(1):21-36.
2006: Kosmider Beata; Wells Robert D
Double-strand breaks in the myotonic dystrophy type 1 and the fragile X syndrome triplet repeat sequences induce different types of mutations in DNA flanking sequences in Escherichia coli.
Nucleic acids research 2006;34(19):5369-82.
2006: Bacolla Albino; Collins Jack R; Gold Bert; Chuzhanova Nadia; Yi Ming; Stephens Robert M; Stefanov Stefan; Olsh Adam; Jakupciak John P; Dean Michael; Lempicki Richard A; Cooper David N; Wells Robert D
Long homopurine*homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region.
Nucleic acids research 2006;34(9):2663-75.
2005: Hebert Micheal L; Wells Robert D
Roles of double-strand breaks, nicks, and gaps in stimulating deletions of CTG.CAG repeats by intramolecular DNA repair.
Journal of molecular biology 2005;353(5):961-79.
2005: Napierala Marek; Bacolla Albino; Wells Robert D
Increased negative superhelical density in vivo enhances the genetic instability of triplet repeat sequences.
The Journal of biological chemistry 2005;280(45):37366-76.
2005: Wojciechowska Marzena; Bacolla Albino; Larson Jacquelynn E; Wells Robert D
The myotonic dystrophy type 1 triplet repeat sequence induces gross deletions and inversions.
The Journal of biological chemistry 2005;280(2):941-52.
2005: Wells Robert D; Dere Ruhee; Hebert Micheal L; Napierala Marek; Son Leslie S
Advances in mechanisms of genetic instability related to hereditary neurological diseases.
Nucleic acids research 2005;33(12):3785-98.
2004: Bacolla Albino; Wells Robert D
Non-B DNA conformations, genomic rearrangements, and human disease.
The Journal of biological chemistry 2004;279(46):47411-4.
2004: Dere Ruhee; Napierala Marek; Ranum Laura P W; Wells Robert D
Hairpin structure-forming propensity of the (CCTG.CAGG) tetranucleotide repeats contributes to the genetic instability associated with myotonic dystrophy type 2.
The Journal of biological chemistry 2004;279(40):41715-26.
2004: Bacolla Albino; Jaworski Adam; Larson Jacquelynn E; Jakupciak John P; Chuzhanova Nadia; Abeysinghe Shaun S; O'Connell Catherine D; Cooper David N; Wells Robert D
Breakpoints of gross deletions coincide with non-B DNA conformations.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14162-7.
2004: Hebert Micheal L; Spitz Leslie A; Wells Robert D
DNA double-strand breaks induce deletion of CTG.CAG repeats in an orientation-dependent manner in Escherichia coli.
Journal of molecular biology 2004;336(3):655-72.
2004: Vetcher Alexandre A; Wells Robert D
Sticky DNA formation in vivo alters the plasmid dimer/monomer ratio.
The Journal of biological chemistry 2004;279(8):6434-43.
2004: Napierala Marek; Dere Ruhee; Vetcher Alexandre; Wells Robert D
Structure-dependent recombination hot spot activity of GAA.TTC sequences from intron 1 of the Friedreich's ataxia gene.
The Journal of biological chemistry 2004;279(8):6444-54.
2004: Mochmann Liliana H; Wells Robert D
Transcription influences the types of deletion and expansion products in an orientation-dependent manner from GAC*GTC repeats.
Nucleic acids research 2004;32(15):4469-79.
2003: Meservy James L; Sargent R Geoffrey; Iyer Ravi R; Chan Fung; McKenzie Gregory J; Wells Robert D; Wilson John H
Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells.
Molecular and cellular biology 2003;23(9):3152-62.
2002: Vetcher Alexandre A; Napierala Marek; Wells Robert D
Sticky DNA: effect of the polypurine.polypyrimidine sequence.
The Journal of biological chemistry 2002;277(42):39228-34.
2002: Vetcher Alexandre A; Napierala Marek; Iyer Ravi R; Chastain Paul D; Griffith Jack D; Wells Robert D
Sticky DNA, a long GAA.GAA.TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene.
The Journal of biological chemistry 2002;277(42):39217-27.
2002: Pluciennik Anna; Iyer Ravi R; Napierala Marek; Larson Jacquelynn E; Filutowicz Marcin; Wells Robert D
Long CTG.CAG repeats from myotonic dystrophy are preferred sites for intermolecular recombination.
The Journal of biological chemistry 2002;277(37):34074-86.
2002: Napierala Marek; Parniewski Pawel; Pluciennik Anna; Wells Robert D
Long CTG.CAG repeat sequences markedly stimulate intramolecular recombination.
The Journal of biological chemistry 2002;277(37):34087-100.
2002: Wells Robert D
How I became a biochemist.
IUBMB life 2002;53(2):137-8.
2001: Sakamoto N; Ohshima K; Montermini L; Pandolfo M; Wells R D
Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription.
The Journal of biological chemistry 2001;276(29):27171-7.
2001: Sakamoto N; Larson J E; Iyer R R; Montermini L; Pandolfo M; Wells R D
GGA*TCC-interrupted triplets in long GAA*TTC repeats inhibit the formation of triplex and sticky DNA structures, alleviate transcription inhibition, and reduce genetic instabilities.
The Journal of biological chemistry 2001;276(29):27178-87.
2001: Bacolla A; Pradhan S; Larson J E; Roberts R J; Wells R D
Recombinant human DNA (cytosine-5) methyltransferase. III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGG.CCG sequence.
The Journal of biological chemistry 2001;276(21):18605-13.
2001: Bacolla A; Jaworski A; Connors T D; Wells R D
Pkd1 unusual DNA conformations are recognized by nucleotide excision repair.
The Journal of biological chemistry 2001;276(21):18597-604.
2001: Bowater R P; Wells R D
The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders.
Progress in nucleic acid research and molecular biology 2001;66():159-202.
2000: Jakupciak J P; Wells R D
Genetic instabilities of triplet repeat sequences by recombination.
IUBMB life 2000;50(6):355-9.
2000: Jakupciak J P; Wells R D
Gene conversion (recombination) mediates expansions of CTG[middle dot]CAG repeats.
The Journal of biological chemistry 2000;275(51):40003-13.
2000: Pluciennik A; Iyer R R; Parniewski P; Wells R D
Tandem duplication. A novel type of triplet repeat instability.
The Journal of biological chemistry 2000;275(37):28386-97.
2000: Parniewski P; Jaworski A; Wells R D; Bowater R P
Length of CTG.CAG repeats determines the influence of mismatch repair on genetic instability.
Journal of molecular biology 2000;299(4):865-74.
2000: Iyer R R; Pluciennik A; Rosche W A; Sinden R R; Wells R D
DNA polymerase III proofreading mutants enhance the expansion and deletion of triplet repeat sequences in Escherichia coli.
The Journal of biological chemistry 2000;275(3):2174-84.
1999: Ohshima K; Sakamoto N; Labuda M; Poirier J; Moseley M L; Montermini L; Ranum L P; Wells R D; Pandolfo M
A nonpathogenic GAAGGA repeat in the Friedreich gene: implications for pathogenesis.
Neurology 1999;53(8):1854-7.
1999: Bacolla A; Pradhan S; Roberts R J; Wells R D
Recombinant human DNA (cytosine-5) methyltransferase. II. Steady-state kinetics reveal allosteric activation by methylated dna.
The Journal of biological chemistry 1999;274(46):33011-9.
1999: Pradhan S; Bacolla A; Wells R D; Roberts R J
Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation.
The Journal of biological chemistry 1999;274(46):33002-10.
1999: Jakupciak J P; Wells R D
Genetic instabilities in (CTG.CAG) repeats occur by recombination.
The Journal of biological chemistry 1999;274(33):23468-79.
1999: Sakamoto N; Chastain P D; Parniewski P; Ohshima K; Pandolfo M; Griffith J D; Wells R D
Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia.
Molecular cell 1999;3(4):465-75.
1999: Iyer R R; Wells R D
Expansion and deletion of triplet repeat sequences in Escherichia coli occur on the leading strand of DNA replication.
The Journal of biological chemistry 1999;274(6):3865-77.
1999: Parniewski P; Bacolla A; Jaworski A; Wells R D
Nucleotide excision repair affects the stability of long transcribed (CTG*CAG) tracts in an orientation-dependent manner in Escherichia coli.
Nucleic acids research 1999;27(2):616-23.
1998: Wells R D; Parniewski P; Pluciennik A; Bacolla A; Gellibolian R; Jaworski A
Small slipped register genetic instabilities in Escherichia coli in triplet repeat sequences associated with hereditary neurological diseases.
The Journal of biological chemistry 1998;273(31):19532-41.
1998: Ohshima K; Montermini L; Wells R D; Pandolfo M
Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo.
The Journal of biological chemistry 1998;273(23):14588-95.
1998: Wells R D; Bacolla A; Bowater R P
Instabilities of triplet repeats: factors and mechanisms.
Results and problems in cell differentiation 1998;21():133-65.
1997: Bowater R P; Jaworski A; Larson J E; Parniewski P; Wells R D
Transcription increases the deletion frequency of long CTG.CAG triplet repeats from plasmids in Escherichia coli.
Nucleic acids research 1997;25(14):2861-8.
1997: Ohshima K; Wells R D
Hairpin formation during DNA synthesis primer realignment in vitro in triplet repeat sequences from human hereditary disease genes.
The Journal of biological chemistry 1997;272(27):16798-806.
1997: Gellibolian R; Bacolla A; Wells R D
Triplet repeat instability and DNA topology: an expansion model based on statistical mechanics.
The Journal of biological chemistry 1997;272(27):16793-7.
1997: Bacolla A; Gellibolian R; Shimizu M; Amirhaeri S; Kang S; Ohshima K; Larson J E; Harvey S C; Stollar B D; Wells R D
Flexible DNA: genetically unstable CTG.CAG and CGG.CCG from human hereditary neuromuscular disease genes.
The Journal of biological chemistry 1997;272(27):16783-92.
1996: Bowater R P; Rosche W A; Jaworski A; Sinden R R; Wells R D
Relationship between Escherichia coli growth and deletions of CTG.CAG triplet repeats in plasmids.
Journal of molecular biology 1996;264(1):82-96.
1996: Rosche W A; Jaworski A; Kang S; Kramer S F; Larson J E; Geidroc D P; Wells R D; Sinden R R
Single-stranded DNA-binding protein enhances the stability of CTG triplet repeats in Escherichia coli.
Journal of bacteriology 1996;178(16):5042-4.
1996: Ohshima K; Kang S; Larson J E; Wells R D
TTA.TAA triplet repeats in plasmids form a non-H bonded structure.
The Journal of biological chemistry 1996;271(28):16784-91.
1996: Ohshima K; Kang S; Larson J E; Wells R D
Cloning, characterization, and properties of seven triplet repeat DNA sequences.
The Journal of biological chemistry 1996;271(28):16773-83.
1996: Kang S; Ohshima K; Jaworski A; Wells R D
CTG triplet repeats from the myotonic dystrophy gene are expanded in Escherichia coli distal to the replication origin as a single large event.
Journal of molecular biology 1996;258(4):543-7.
1996: Wells R D
Molecular basis of genetic instability of triplet repeats.
The Journal of biological chemistry 1996;271(6):2875-8.
1996: Ohshima K; Kang S; Wells R D
CTG triplet repeats from human hereditary diseases are dominant genetic expansion products in Escherichia coli.
The Journal of biological chemistry 1996;271(4):1853-6.
1995: Kang S; Ohshima K; Shimizu M; Amirhaeri S; Wells R D
Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes.
The Journal of biological chemistry 1995;270(45):27014-21.
1995: Jaworski A; Rosche W A; Gellibolian R; Kang S; Shimizu M; Bowater R P; Sinden R R; Wells R D
Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11019-23.
1995: Bacolla A; Ulrich M J; Larson J E; Ley T J; Wells R D
An intramolecular triplex in the human gamma-globin 5'-flanking region is altered by point mutations associated with hereditary persistence of fetal hemoglobin.
The Journal of biological chemistry 1995;270(41):24556-63.
1995: Kang S; Jaworski A; Ohshima K; Wells R D
Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli.
Nature genetics 1995;10(2):213-8.
1995: Amirhaeri S; Wohlrab F; Wells R D
Differential effects of simple repeating DNA sequences on gene expression from the SV40 early promoter.
The Journal of biological chemistry 1995;270(7):3313-9.
1994: Lukomski S; Wells R D
Left-handed Z-DNA and in vivo supercoil density in the Escherichia coli chromosome.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9980-4.
1994: Kang S; Wells R D
Zinc destabilizes DNA Watson-Crick pairs at AGCT.
The Journal of biological chemistry 1994;269(13):9528-32.
1992: Kang S; Wells R D
Central non-Pur.Pyr sequences in oligo(dG.dC) tracts and metal ions influence the formation of intramolecular DNA triplex isomers.
The Journal of biological chemistry 1992;267(29):20887-91.
1992: Kang S; Wohlrab F; Wells R D
GC-rich flanking tracts decrease the kinetics of intramolecular DNA triplex formation.
The Journal of biological chemistry 1992;267(27):19435-42.
1992: Panyutin I G; Wells R D
Nodule DNA in the (GA)37.(CT)37 insert in superhelical plasmids.
The Journal of biological chemistry 1992;267(8):5495-501.
1992: Hartman D A; Kuo S R; Broker T R; Chow L T; Wells R D
Intermolecular triplex formation distorts the DNA duplex in the regulatory region of human papillomavirus type-11.
The Journal of biological chemistry 1992;267(8):5488-94.
1992: Rahmouni A R; Wells R D
Direct evidence for the effect of transcription on local DNA supercoiling in vivo.
Journal of molecular biology 1992;223(1):131-44.
1992: Kang S M; Wohlrab F; Wells R D
Metal ions cause the isomerization of certain intramolecular triplexes.
The Journal of biological chemistry 1992;267(2):1259-64.
1991: Venditti S; Wells R D
A DNA conformational alteration induced by a neighboring oligopurine tract on GAATTA enables nicking by EcoRI.
The Journal of biological chemistry 1991;266(25):16786-90.
1991: Wohlrab F; Chatterjee S; Wells R D
The herpes simplex virus 1 segment inversion site is specifically cleaved by a virus-induced nuclear endonuclease.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6432-6.
1991: Jaworski A; Higgins N P; Wells R D; Zacharias W
Topoisomerase mutants and physiological conditions control supercoiling and Z-DNA formation in vivo.
The Journal of biological chemistry 1991;266(4):2576-81.
1990: Bianchi A; Wells R D; Heintz N H; Caddle M S
Sequences near the origin of replication of the DHFR locus of Chinese hamster ovary cells adopt left-handed Z-DNA and triplex structures.
The Journal of biological chemistry 1990;265(35):21789-96.
1990: Rajagopalan M; Rahmouni A R; Wells R D
Flanking AT-rich tracts cause a structural distortion in Z-DNA in plasmids.
The Journal of biological chemistry 1990;265(28):17294-9.
1990: Collier D A; Wells R D
Effect of length, supercoiling, and pH on intramolecular triplex formation. Multiple conformers at pur.pyr mirror repeats.
The Journal of biological chemistry 1990;265(18):10652-8.
1990: Zacharias W; Jaworski A; Wells R D
Cytosine methylation enhances Z-DNA formation in vivo.
Journal of bacteriology 1990;172(6):3278-83.
1990: Shimizu M; Hanvey J C; Wells R D
Multiple non-B-DNA conformations of polypurine.polypyrimidine sequences in plasmids.
Biochemistry 1990;29(19):4704-13.
1990: Hanvey J C; Shimizu M; Wells R D
Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix.
Nucleic acids research 1990;18(1):157-61.
1989: Rahmouni A R; Wells R D
Stabilization of Z DNA in vivo by localized supercoiling.
Science (New York, N.Y.) 1989;246(4928):358-63.
1989: Jaworski A; Blaho J A; Larson J E; Shimizu M; Wells R D
Tetracycline promoter mutations decrease non-B DNA structural transitions, negative linking differences and deletions in recombinant plasmids in Escherichia coli.
Journal of molecular biology 1989;207(3):513-26.
1989: Wohlrab F; Wells R D
Slight changes in conditions influence the family of non-B-DNA conformations of the herpes simplex virus type 1 DR2 repeats.
The Journal of biological chemistry 1989;264(14):8207-13.
1989: Hanvey J C; Shimizu M; Wells R D
Intramolecular DNA triplexes in supercoiled plasmids. II. Effect of base composition and noncentral interruptions on formation and stability.
The Journal of biological chemistry 1989;264(10):5950-6.
1989: Shimizu M; Hanvey J C; Wells R D
Intramolecular DNA triplexes in supercoiled plasmids. I. Effect of loop size on formation and stability.
The Journal of biological chemistry 1989;264(10):5944-9.
1988: Zacharias W; Caserta M; O'Connor T R; Larson J E; Wells R D
Cytosine methylation as an effector of right-handed to left-handed DNA structural transitions.
Gene 1988;74(1):221-4.
1988: Jaworski A; Zacharias W; Hsieh W T; Blaho J A; Larson J E; Wells R D
In vivo existence of left-handed DNA.
Gene 1988;74(1):215-20.
1988: Wells R D; Collier D A; Hanvey J C; Shimizu M; Wohlrab F
The chemistry and biology of unusual DNA structures adopted by oligopurine.oligopyrimidine sequences.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(14):2939-49.
1988: Zacharias W; Jaworski A; Larson J E; Wells R D
The B- to Z-DNA equilibrium in vivo is perturbed by biological processes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7069-73.
1988: Blaho J A; Larson J E; McLean M J; Wells R D
Multiple DNA secondary structures in perfect inverted repeat inserts in plasmids. Right-handed B-DNA, cruciforms, and left-handed Z-DNA.
The Journal of biological chemistry 1988;263(28):14446-55.
1988: Hanvey J C; Shimizu M; Wells R D
Intramolecular DNA triplexes in supercoiled plasmids.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6292-6.
1988: Stevens W C; Huang D H; Wells R D; Krishna N R
1H NMR study of the solution structure of the self-complementary dodecanucleotide d(TGCA)3.
Nucleic acids research 1988;16(14B):7133-43.
1988: Thompson J A; Wells R D
HPLC in nucleic acids research.
Nature 1988;334(6177):87-8.
1988: Collier D A; Griffin J A; Wells R D
Non-B right-handed DNA conformations of homopurine.homopyrimidine sequences in the murine immunoglobulin C alpha switch region.
The Journal of biological chemistry 1988;263(15):7397-405.
1988: McLean M J; Lee J W; Wells R D
Characteristics of Z-DNA helices formed by imperfect (purine-pyrimidine) sequences in plasmids.
The Journal of biological chemistry 1988;263(15):7378-85.
1988: Hanvey J C; Klysik J; Wells R D
Influence of DNA sequence on the formation of non-B right-handed helices in oligopurine.oligopyrimidine inserts in plasmids.
The Journal of biological chemistry 1988;263(15):7386-96.
1988: McLean M J; Wells R D
The role of DNA sequence in the formation of Z-DNA versus cruciforms in plasmids.
The Journal of biological chemistry 1988;263(15):7370-7.
1988: Amirhaeri S; Wohlrab F; Major E O; Wells R D
Unusual DNA structure in the regulatory region of the human papovavirus JC virus.
Journal of virology 1988;62(3):922-31.
1988: Wells R D
Unusual DNA structures.
The Journal of biological chemistry 1988;263(3):1095-8.
1987: Jaworski A; Hsieh W T; Blaho J A; Larson J E; Wells R D
Left-handed DNA in vivo.
Science (New York, N.Y.) 1987;238(4828):773-7.
1987: Whitson P A; Hsieh W T; Wells R D; Matthews K S
Influence of supercoiling and sequence context on operator DNA binding with lac repressor.
The Journal of biological chemistry 1987;262(30):14592-9.
1987: Hsieh W T; Whitson P A; Matthews K S; Wells R D
Influence of sequence and distance between two operators on interaction with the lac repressor.
The Journal of biological chemistry 1987;262(30):14583-91.
1987: Hsieh W T; Wells R D
Influence of negative supercoiling and of the proximity of left-handed Z-DNA on the Escherichia coli lactose repressor-operator interaction.
The Journal of biological chemistry 1987;262(30):14576-82.
1987: McLean M J; Larson J E; Wohlrab F; Wells R D
Reaction conditions affect the specificity of bromoacetaldehyde as a probe for DNA cruciforms and B-Z junctions.
Nucleic acids research 1987;15(17):6917-35.
1987: Bergen H R; Losman M J; O'Connor T; Zacharias W; Larson J E; Accavitti M A; Wells R D; Koopman W J
Specificity of monoclonal anti-Z-DNA antibodies from unimmunized MRL/Mp-lpr/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(3):743-8.
1987: Wohlrab F; McLean M J; Wells R D
The segment inversion site of herpes simplex virus type 1 adopts a novel DNA structure.
The Journal of biological chemistry 1987;262(13):6407-16.
1987: Whitson P A; Hsieh W T; Wells R D; Matthews K S
Supercoiling facilitates lac operator-repressor-pseudooperator interactions.
The Journal of biological chemistry 1987;262(11):4943-6.
1987: Caserta M; Zacharias W; Nwankwo D; Wilson G G; Wells R D
Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase.
The Journal of biological chemistry 1987;262(10):4770-7.
1987: Wohlrab F; Wells R D
Enzymatic probes for left-handed Z-DNA.
Gene amplification and analysis 1987;5():247-56.
1986: McLean M J; Blaho J A; Kilpatrick M W; Wells R D
Consecutive A X T pairs can adopt a left-handed DNA structure.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(16):5884-8.
1986: Galazka G; Palecek E; Wells R D; Klysik J
Site-specific OsO4 modification of the B-Z junctions formed at the (dA-dC)32 region in supercoiled DNA.
The Journal of biological chemistry 1986;261(15):7093-8.
1984: Zacharias W; Larson J E; Kilpatrick M W; Wells R D
HhaI methylase and restriction endonuclease as probes for B to Z DNA conformational changes in d(GCGC) sequences.
Nucleic acids research 1984;12(20):7677-92.
1984: Marini J C; Effron P N; Goodman T C; Singleton C K; Wells R D; Wartell R M; Englund P T
Physical characterization of a kinetoplast DNA fragment with unusual properties.
The Journal of biological chemistry 1984;259(14):8974-9.
1984: Kilpatrick M W; Klysik J; Singleton C K; Zarling D A; Jovin T M; Hanau L H; Erlanger B F; Wells R D
Intervening sequences in human fetal globin genes adopt left-handed Z helices.
The Journal of biological chemistry 1984;259(11):7268-74.
1984: Singleton C K; Kilpatrick M W; Wells R D
S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences.
The Journal of biological chemistry 1984;259(3):1963-7.
1983: O'Connor T; Kilpatrick M W; Klysik J; Larson J E; Martin J C; Singleton C K; Stirdivant S M; Zacharias W; Wells R D
Left-handed Z-DNA helices in polymers, restriction fragments, and recombinant plasmids.
Journal of biomolecular structure & dynamics 1983;1(4):999-1009.
1983: Wartell R M; Harrell J T; Zacharias W; Wells R D
Raman spectroscopy study of the B-Z transition in (dG-dC)n.(dG-dC)n and a DNA restriction fragment.
Journal of biomolecular structure & dynamics 1983;1(1):83-96.
1983: Klysik J; Stirdivant S M; Singleton C K; Zacharias W; Wells R D
Effects of 5 cytosine methylation on the B-Z transition in DNA restriction fragments and recombinant plasmids.
Journal of molecular biology 1983;168(1):51-71.
1983: Singleton C K; Klysik J; Wells R D
Conformational flexibility of junctions between contiguous B- and Z-DNAs in supercoiled plasmids.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(9):2447-51.
1983: Wells R D; Brennan R; Chapman K A; Goodman T C; Hart P A; Hillen W; Kellogg D R; Kilpatrick M W; Klein R D; Klysik J; Lambert P F; Larson J E; Miglietta J J; Neuendorf S K; O'Connor T R; Singleton C K; Stirdivant S M; Veneziale C M; Wartell R M; Zacharias W
Left-handed DNA helices, supercoiling, and the B-Z junction.
Cold Spring Harbor symposia on quantitative biology 1983;47 Pt 1():77-84.
1982: Singleton C K; Klysik J; Stirdivant S M; Wells R D
Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions.
Nature 1982;299(5881):312-6.
1982: Stirdivant S M; Klysik J; Wells R D
Energetic and structural inter-relationship between DNA supercoiling and the right- to left-handed Z helix transitions in recombinant plasmids.
The Journal of biological chemistry 1982;257(17):10159-65.
1982: Klysik J; Stirdivant S M; Wells R D
Left-handed DNA. Cloning, characterization, and instability of inserts containing different lengths of (dC-dG) in Escherichia coli.
The Journal of biological chemistry 1982;257(17):10152-8.
1982: Wells R D; Miglietta J J; Klysik J; Larson J E; Stirdivant S M; Zacharias W
Spectroscopic studies on acetylaminofluorene-modified (dT-dG)n . (dC-dA)n suggest a left-handed conformation.
The Journal of biological chemistry 1982;257(17):10166-71.
1982: Wartell R M; Klysik J; Hillen W; Wells R D
Junction between Z and B conformations in a DNA restriction fragment: evaluation by Raman spectroscopy.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(8):2549-53.
1982: Zacharias W; Larson J E; Klysik J; Stirdivant S M; Wells R D
Conditions which cause the right-handed to left-handed DNA conformational transitions. Evidence for several types of left-handed DNA structures in solution.
The Journal of biological chemistry 1982;257(6):2775-82.
1981: Klysik J; Stirdivant S M; Larson J E; Hart P A; Wells R D
Left-handed DNA in restriction fragments and a recombinant plasmid.
Nature 1981;290(5808):672-7.
1980: Wells R D; Goodman T C; Hillen W; Horn G T; Klein R D; Larson J E; Müller U R; Neuendorf S K; Panayotatos N; Stirdivant S M
DNA structure and gene regulation.
Progress in nucleic acid research and molecular biology 1980;24():167-267.
1980: Wells R D; Hardies S C; Horn G T; Klein B; Larson J E; Neuendorf S K; Panayotatos N; Patient R K; Selsing E
RPC-5 column chromatography for the isolation of DNA fragments.
Methods in enzymology 1980;65(1):327-47.

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