Samuel Wells

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You Y Nancy; Lakhani Vipul; Wells Samuel A
New directions in the treatment of thyroid cancer.
You Y Nancy; Wells Samuel A
Role of surgeons in clinical trials for thyroid cancer.
You Y Nancy; Lakhani Vipul T; Wells Samuel A
The role of prophylactic surgery in cancer prevention.

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All Publications

2007: You Y Nancy; Lakhani Vipul; Wells Samuel A
New directions in the treatment of thyroid cancer.
Journal of the American College of Surgeons 2007;205(4 Suppl):S45-8.
2007: You Y Nancy; Wells Samuel A
Role of surgeons in clinical trials for thyroid cancer.
World journal of surgery 2007;31(5):987-95.
2007: You Y Nancy; Lakhani Vipul T; Wells Samuel A
The role of prophylactic surgery in cancer prevention.
World journal of surgery 2007;31(3):450-64.
2007: Lakhani Vipul T; You Y Nancy; Wells Samuel A
The multiple endocrine neoplasia syndromes.
Annual review of medicine 2007;58():253-65.
2006: You Y Nancy; Lakhani Vipul; Wells Samuel A; Moley Jeffrey F
Medullary thyroid cancer.
Surgical oncology clinics of North America 2006;15(3):639-60.
2006: You Y Nancy; Wells Samuel A;
Clinical trials in surgery: the role of the American College of Surgeons Oncology Group.
World journal of surgery 2006;30(7):1147-51.
2005: Cohen Mark S; Dilley William G; Wells Samuel A; Moley Jeffrey F; Doherty Gerard M; Sicard Gregorio A; Skinner Michael A; Norton Jeffrey A; DeBenedetti Mary K; Lairmore Terry C
Long-term functionality of cryopreserved parathyroid autografts: a 13-year prospective analysis.
Surgery 2005;138(6):1033-40; discussion 1040-1.
2005: Skinner Michael A; Moley Jeffrey A; Dilley William G; Owzar Kouros; Debenedetti Mary K; Wells Samuel A
Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A.
The New England journal of medicine 2005;353(11):1105-13.
2005: Posther K E; Wells S A
The future of surgical research: the role of the American College of Surgeons Oncology Group.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2005;31(6):695-701.
2004: Quayle Frank J; Benveniste Ronald; DeBenedetti Mary K; Wells Samuel A; Moley Jeffrey F
Hereditary medullary thyroid carcinoma in patients greater than 50 years old.
Surgery 2004;136(6):1116-21.
2002: Wells Samuel A; Debenedetti Mary K; Doherty Gerard M
Recurrent or persistent hyperparathyroidism.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17 Suppl 2():N158-62.
2002: Wells Samuel A
Surgeons and surgical trials-why we must assume a leadership role.
Surgery 2002;132(3):519-20.
2002: Cohen Mark S; Phay John E; Albinson Charlotte; DeBenedetti Mary K; Skinner Michael A; Lairmore Terry C; Doherty Gerard M; Balfe Dennis M; Wells Samuel A; Moley Jeffrey F
Gastrointestinal manifestations of multiple endocrine neoplasia type 2.
Annals of surgery 2002;235(5):648-54; discussion 654-5.
2002: Wells Samuel A
David Coston Sabiston, Jr.: surgeon, scientist, teacher, and leader.
Clinical cardiology 2002;25(1):43-5.
2000: Wells S A; Franz C
Medullary carcinoma of the thyroid gland.
World journal of surgery 2000;24(8):952-6.
1999: Moley J F; Wells S A
Compartment-mediated dissection for papillary thyroid cancer.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 1999;384(1):9-15.
1999: Herfarth K K; Brent T P; Danam R P; Remack J S; Kodner I J; Wells S A; Goodfellow P J
A specific CpG methylation pattern of the MGMT promoter region associated with reduced MGMT expression in primary colorectal cancers.
Molecular carcinogenesis 1999;24(2):90-8.
1999: Mutch M G; Dilley W G; Sanjurjo F; DeBenedetti M K; Doherty G M; Wells S A; Goodfellow P J; Lairmore T C
Germline mutations in the multiple endocrine neoplasia type 1 gene: evidence for frequent splicing defects.
Human mutation 1999;13(3):175-85.
1998: Moley J F; Debenedetti M K; Dilley W G; Tisell L E; Wells S A
Surgical management of patients with persistent or recurrent medullary thyroid cancer.
Journal of internal medicine 1998;243(6):521-6.
1998: Doherty G M; Olson J A; Frisella M M; Lairmore T C; Wells S A; Norton J A
Lethality of multiple endocrine neoplasia type I.
World journal of surgery 1998;22(6):581-6; discussion 586-7.
1998: Wells S A
Presidential Address. Transitions.
Annals of surgery 1998;227(5):609-17.
1998: Klaus K; Herfarth F; Ogunbiyi O A; Moley J F; Kodner I J; Wells S A; Goodfellow P J
Four new mutations in the DNA mismatch repair gene MLH1 in colorectal cancers with microsatellite instability. Mutations in brief no. 157. Online.
Human mutation 1998;12(1):73.
1998: Wells S A; Skinner M A
Prophylactic thyroidectomy, based on direct genetic testing, in patients at risk for the multiple endocrine neoplasia type 2 syndromes.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1998;106(1):29-34.
1997: Mutch M G; Frisella M M; DeBenedetti M K; Doherty G M; Norton J A; Wells S A; Lairmore T C
Pancreatic polypeptide is a useful plasma marker for radiographically evident pancreatic islet cell tumors in patients with multiple endocrine neoplasia type 1.
Surgery 1997;122(6):1012-9; discussion 1019-20.
1997: Musholt P B; Musholt T J; Goodfellow P J; Zehnbauer B A; Wells S A; Moley J F
"Cold" single-strand conformational variants for mutation analysis of the RET protooncogene.
Surgery 1997;122(2):363-70; discussion 370-1.
1997: Skinner M A; Wells S A
Medullary carcinoma of the thyroid gland and the MEN 2 syndromes.
Seminars in pediatric surgery 1997;6(3):134-40.
1997: Kitamura Y; Goodfellow P J; Shimizu K; Nagahama M; Ito K; Kitagawa W; Akasu H; Takami H; Tanaka S; Wells S A
Novel germline RET proto-oncogene mutations associated with medullary thyroid carcinoma (MTC): mutation analysis in Japanese patients with MTC.
Oncogene 1997;14(25):3103-6.
1997: Tung W S; Shevlin D W; Kaleem Z; Tribune D J; Wells S A; Goodfellow P J
Allelotype of follicular thyroid carcinomas reveals genetic instability consistent with frequent nondisjunctional chromosomal loss.
Genes, chromosomes & cancer 1997;19(1):43-51.
1997: Musholt T J; Goodfellow P J; Scheumann G F; Pichlmayr R; Wells S A; Moley J F
Differential display in primary and metastatic medullary thyroid carcinoma.
The Journal of surgical research 1997;69(1):94-100.
1997: Skinner M A; Norton J A; Moley J F; DeBenedetti M K; Wells S A
Heterotopic autotransplantation of parathyroid tissue in children undergoing total thyroidectomy.
Journal of pediatric surgery 1997;32(3):510-3.
1997: Herfarth K K; Wells S A
Parathyroid glands and the multiple endocrine neoplasia syndromes and familial hypocalciuric hypercalcemia.
Seminars in surgical oncology 1997;13(2):114-24.
1997: Herfarth K K; Kodner I J; Whelan A J; Ivanovich J L; Bracamontes J R; Wells S A; Goodfellow P J
Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instability.
Genes, chromosomes & cancer 1997;18(1):42-9.
1996: Herfarth K K; Bartsch D; Doherty G M; Wells S A; Lairmore T C
Surgical management of hyperparathyroidism in patients with multiple endocrine neoplasia type 2A.
Surgery 1996;120(6):966-73; discussion 973-4.
1996: Lairmore T C; Frisella M M; Wells S A
Genetic testing and early thyroidectomy for inherited medullary thyroid carcinoma.
Annals of medicine 1996;28(5):401-6.
1996: Wells S A
The surgical scientist.
Annals of surgery 1996;224(3):239-54.
1996: Olson J A; DeBenedetti M K; Baumann D S; Wells S A
Parathyroid autotransplantation during thyroidectomy. Results of long-term follow-up.
Annals of surgery 1996;223(5):472-8; discussion 478-80.
1996: Bartsch D; Shevlin D W; Callery M P; Norton J A; Wells S A; Goodfellow P J
Reduced survival in patients with ductal pancreatic adenocarcinoma associated with CDKN2 mutation.
Journal of the National Cancer Institute 1996;88(10):680-2.
1996: Bartsch D; Peiffer S L; Kaleem Z; Wells S A; Goodfellow P J
Mxi1 tumor suppressor gene is not mutated in primary pancreatic adenocarcinoma.
Cancer letters 1996;102(1-2):73-6.
1996: Skinner M A; DeBenedetti M K; Moley J F; Norton J A; Wells S A
Medullary thyroid carcinoma in children with multiple endocrine neoplasia types 2A and 2B.
Journal of pediatric surgery 1996;31(1):177-81; discussion 181-2.
1996: Tung W S; Shevlin D W; Bartsch D; Norton J A; Wells S A; Goodfellow P J
Infrequent CDKN2 mutation in human differentiated thyroid cancers.
Molecular carcinogenesis 1996;15(1):5-10.
1996: Tisell L E; Dilley W G; Wells S A
Progression of postoperative residual medullary thyroid carcinoma as monitored by plasma calcitonin levels.
Surgery 1996;119(1):34-9.
1995: Bartsch D; Shevlin D W; Tung W S; Kisker O; Wells S A; Goodfellow P J
Frequent mutations of CDKN2 in primary pancreatic adenocarcinomas.
Genes, chromosomes & cancer 1995;14(3):189-95.
1995: Kitamura Y; Scavarda N; Wells S A; Jackson C E; Goodfellow P J
Two maternally derived missense mutations in the tyrosine kinase domain of the RET protooncogene in a patient with de novo MEN 2B.
Human molecular genetics 1995;4(10):1987-8.
1995: Goodfellow P J; Wells S A
RET gene and its implications for cancer.
Journal of the National Cancer Institute 1995;87(20):1515-23.
1994: Carlson K M; Bracamontes J; Jackson C E; Clark R; Lacroix A; Wells S A; Goodfellow P J
Parent-of-origin effects in multiple endocrine neoplasia type 2B.
American journal of human genetics 1994;55(6):1076-82.
1994: Wells S A; Chi D D; Toshima K; Dehner L P; Coffin C M; Dowton S B; Ivanovich J L; DeBenedetti M K; Dilley W G; Moley J F
Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia type 2A.
Annals of surgery 1994;220(3):237-47; discussion 247-50.
1994: Chi D D; Toshima K; Donis-Keller H; Wells S A
Predictive testing for multiple endocrine neoplasia type 2A (MEN 2A) based on the detection of mutations in the RET protooncogene.
Surgery 1994;116(2):124-32; discussion 132-3.
1994: Brunt L M; Mazoujian G; O'Dorisio T M; Wells S A
Stimulation of vasoactive intestinal peptide and neurotensin secretion by pentagastrin in a patient with VIPoma syndrome.
Surgery 1994;115(3):362-9.
1994: Wells S A; Donis-Keller H
Current perspectives on the diagnosis and management of patients with multiple endocrine neoplasia type 2 syndromes.
Endocrinology and metabolism clinics of North America 1994;23(1):215-28.
1994: Carlson K M; Dou S; Chi D; Scavarda N; Toshima K; Jackson C E; Wells S A; Goodfellow P J; Donis-Keller H
Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1579-83.
1993: Moley J F; Wells S A; Dilley W G; Tisell L E
Reoperation for recurrent or persistent medullary thyroid cancer.
Surgery 1993;114(6):1090-5; discussion 1095-6.
1993: Howe J R; Norton J A; Wells S A
Prevalence of pheochromocytoma and hyperparathyroidism in multiple endocrine neoplasia type 2A: results of long-term follow-up.
Surgery 1993;114(6):1070-7.
1993: Lairmore T C; Wells S A
Genetic testing for multiple endocrine neoplasia.
The British journal of surgery 1993;80(9):1092-3.
1993: Radford D M; Fair K; Thompson A M; Ritter J H; Holt M; Steinbrueck T; Wallace M; Wells S A; Donis-Keller H R
Allelic loss on a chromosome 17 in ductal carcinoma in situ of the breast.
Cancer research 1993;53(13):2947-9.
1993: Donis-Keller H; Dou S; Chi D; Carlson K M; Toshima K; Lairmore T C; Howe J R; Moley J F; Goodfellow P; Wells S A
Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.
Human molecular genetics 1993;2(7):851-6.
1993: Lairmore T C; Ball D W; Baylin S B; Wells S A
Management of pheochromocytomas in patients with multiple endocrine neoplasia type 2 syndromes.
Annals of surgery 1993;217(6):595-601; discussion 601-3.
1993: Howe J R; Lairmore T C; Veile R; Dou S; Wells S A; Donis-Keller H
Development of a sequence-tagged site for the centromere of chromosome 10: its use in cytogenetic and physical mapping.
Human genetics 1993;91(3):199-204.
1993: Baumann D S; Wells S A
Parathyroid autotransplantation.
Surgery 1993;113(2):130-3.
1993: Lairmore T C; Dou S; Howe J R; Chi D; Carlson K; Veile R; Mishra S K; Wells S A; Donis-Keller H
A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, D10S94, and D10S102) closely linked to the MEN2A locus.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):492-6.
1993: Radford D M; Wells S A
Surgical techniques in breast conservation.
Advances in surgery 1993;26():1-27.
1992: Howe J R; Lairmore T C; Mishra S K; Dou S; Veile R; Wells S A; Donis-Keller H
Improved predictive test for MEN2, using flanking dinucleotide repeats and RFLPs.
American journal of human genetics 1992;51(6):1430-42.
1992: Howe J R; Lairmore T C; Dou S; Mishra S K; Dilley W G; Donis-Keller H; Wells S A
Presymptomatic identification of carriers of the multiple endocrine neoplasia type 2A gene using flanking DNA markers.
Surgery 1992;112(2):219-25; discussion 225-6.
1992: Iwasaki H; Stewart P W; Dilley W G; Holt M S; Steinbrueck T D; Wells S A; Donis-Keller H
A minisatellite and a microsatellite polymorphism within 1.5 kb at the human muscle glycogen phosphorylase (PYGM) locus can be amplified by PCR and have combined informativeness of PIC 0.95.
Genomics 1992;13(1):7-15.
1992: Howe J R; Lairmore T C; Dou S; Veile R; Steinbrueck T; Wells S A; Donis-Keller H
A new RFLP marker D5S348 maps to 5p14.3-15.2, between D5S60 (CRI-R535) and HPRTP2.
Nucleic acids research 1992;20(5):1168.
1992: Moley J F; Brother M B; Fong C T; White P S; Baylin S B; Nelkin B; Wells S A; Brodeur G M
Consistent association of 1p loss of heterozygosity with pheochromocytomas from patients with multiple endocrine neoplasia type 2 syndromes.
Cancer research 1992;52(4):770-4.
1992: Haagensen D E; Stewart P; Dilley W G; Wells S A
Secretion of breast gross cystic disease fluid proteins by T47D breast cancer cells in culture--modulation by steroid hormones.
Breast cancer research and treatment 1992;23(1-2):77-86.
1992: Moley J F; Wallin G K; Brother M B; Kim M; Wells S A; Brodeur G M
Oncogene and growth factor expression in MEN 2 and related tumors.
Henry Ford Hospital medical journal 1992;40(3-4):284-8.
1992: Lairmore T C; Howe J R; Dou S; Veile R; Korte-Sarfaty J A; Wells S A; Donis-Keller H
Isolation of YAC clones from the pericentromeric region of chromosome 10 and development of new genetic markers linked to the multiple endocrine neoplasia type 2A gene.
Henry Ford Hospital medical journal 1992;40(3-4):210-4.
1991: Wells S A; Cooper J D
Closed mediastinal exploration in patients with persistent hyperparathyroidism.
Annals of surgery 1991;214(5):555-61.
1991: Backdahl M; Howe J R; Lairmore T C; Wells S A
The molecular biology of parathyroid disease.
World journal of surgery 1991;15(6):756-62.
1991: Wells S A
Surgical therapy of patients with primary hyperparathyroidism: long-term benefits.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6 Suppl 2():S143-9; discussion S151-2.
1991: Lairmore T C; Wells S A
Medullary carcinoma of the thyroid: current diagnosis and management.
Seminars in surgical oncology 1991;7(2):92-9.
1991: Moley J F; Brother M B; Wells S A; Spengler B A; Biedler J L; Brodeur G M
Low frequency of ras gene mutations in neuroblastomas, pheochromocytomas, and medullary thyroid cancers.
Cancer research 1991;51(6):1596-9.
1991: Lairmore T C; Howe J R; Korte J A; Dilley W G; Aine L; Aine E; Wells S A; Donis-Keller H
Familial medullary thyroid carcinoma and multiple endocrine neoplasia type 2B map to the same region of chromosome 10 as multiple endocrine neoplasia type 2A.
Genomics 1991;9(1):181-92.
1990: Dilley W G; Haagensen D E; Cox C E; Wells S A
Immunologic and steroid binding properties of the GCDFP-24 protein isolated from human breast gross cystic disease fluid.
Breast cancer research and treatment 1990;16(3):253-60.
1990: Decker R A; Toyama W M; O'Neal L W; Telander R L; Wells S A
Evaluation of children with multiple endocrine neoplasia type IIb following thyroidectomy.
Journal of pediatric surgery 1990;25(9):939-43.
1990: Haagensen D E; Dilley W G; Mazoujian G; Wells S A
Review of GCDFP-15. An apocrine marker protein.
Annals of the New York Academy of Sciences 1990;586():161-73.
1990: Seesko H G; Wells S A
Thyroid tumors.
Immunology series 1990;53():431-52.
1990: Wells S A
Multiple endocrine neoplasia type II.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1990;118():70-8.
1989: Decker R A; Wells S A
Multiple endocrine neoplasia.
The Japanese journal of surgery 1989;19(6):645-57.
1989: Wells S A
Scope of quality of care for cancer patients.
Cancer 1989;64(1 Suppl):216-8; discussion 240-3.
1989: Kramer J B; Wells S A
Thyroid carcinoma.
Advances in surgery 1989;22():195-224.
1987: Haagensen D E; Metzgar R S; Sawlivich W; Swenson B; Davis S; Newman E; Zamcheck N; Wells S A; Hansen H J
Evaluation of chimpanzee antiserum to human carcinoembryonic antigen.
Cancer research 1987;47(21):5606-11.
1986: Dilley W G; Haagensen D E; Leight G S; Ammirata S; Davis S R; Silva J S; Zamcheck N; Lokich J J; Wells S A
Fluoxymesterone stimulation of tumor marker secretion in patients with breast carcinoma.
Breast cancer research and treatment 1986;8(3):205-15.
1983: Silva J S; Georgiade G S; Dilley W G; McCarty K S; Wells S A; McCarty K S
Menstrual cycle-dependent variations of breast cyst fluid proteins and sex steroid receptors in the normal human breast.
Cancer 1983;51(7):1297-302.
1983: McCarty K S; Silva J S; Cox E B; Leight G S; Wells S A; McCarty K S
Relationship of age and menopausal status to estrogen receptor content in primary carcinoma of the breast.
Annals of surgery 1983;197(2):123-7.
1983: Dilley W G; Leight G S; Silva J S; Ammirata S; Haagensen D E; Wells S A
Androgen stimulation of gross cystic disease fluid protein and carcinoembryonic antigen in patients with metastatic breast carcinoma.
Journal of the National Cancer Institute 1983;70(1):69-74.
1982: Haagensen D E; Metzgar R S; Swenson B; Dilley W G; Cox C E; Davis S; Murdoch J; Zamcheck N; Wells S A
Carcinoembryonic antigen in nonhuman primates.
Journal of the National Cancer Institute 1982;69(5):1073-6.
1982: Silva J S; Cox C E; Wells S A; Paull D; Dilley W G; McCarty K S; Fetter B F; Glaubitz L C; McCarty K S
Biochemical correlates of morphologic differentiation in human breast cancer.
Surgery 1982;92(3):443-9.
1982: Sullivan D C; Silva J S; Cox C E; Haagensen D E; Harris C C; Briner W H; Wells S A
Localization of I-131-labeled goat and primate anti-carcinoembryonic antigen(CEA) antibodies in patients with cancer.
Investigative radiology 1982;17(4):350-5.
1982: Silva J S; Leight G S; Haagensen D E; Tallos P B; Cox E B; Dilley W G; Wells S A
Quantitation of response to therapy in patients with metastatic breast carcinoma by serial analysis of plasma gross cystic disease fluid protein and carcinoembryonic antigen.
Cancer 1982;49(6):1236-42.
1981: Barry W F; Wells S A; Cox C E; Haagensen D E
Clinical and radiographic correlations in breast cancer patients with osseous metastases.
Skeletal radiology 1981;6(1):27-32.
1980: McCarty K S; Cox C; Silva J S; Woodard B H; Mossler J A; Haagensen D E; Barton T K; McCarty K S; Wells S A
Comparison of sex steroid receptor analyses and carcinoembryonic antigen with clinical response to hormone therapy.
Cancer 1980;46(12 Suppl):2846-50.
1980: Haagensen D E; Cox C E; Dilley W G; Hensley M; Murdoch J; Newman E S; Wells S A
Evaluation of baboon antiserum to carcinoembryonic antigen.
Clinical chemistry 1980;26(13):1787-90.
1980: Haagensen D E; Gall S A; Brazy J E; Giannola J; Wells S A
Analysis of amniotic fluid, maternal plasma, and cord blood for a human breast gross cystic disease fluid protein.
American journal of obstetrics and gynecology 1980;138(1):25-32.
1980: Haagensen D E; Barry W F; McCook T A; Giannola J; Ammirata S; Wells S A
The value of serial plasma levels of carcinoembryonic antigen and gross cyst disease fluid protein in patients with breast carcinoma and osseous metastases.
Annals of surgery 1980;191(5):599-603.

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