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Anton Wellstein

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Olga Catalina Rodriguez; Eveline E Vietsch; Anton Wellstein; Chris Albanese; Jill Bargonetti; Jason Catania; Sujatra Choudhury; Vamsi Kolukula; Anju Preet; Katherine Reynoso; Maria Laura Avantaggiati
Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy.
Olga Catalina-Rodriguez; Amato J Giaccia; Eric Glasgow; Vamsi K Kolukula; Ferdinando Palmieri; Anju Preet; York Tomita; Anton Wellstein; Chris Albanese; Stephen Byers; Maria Laura Avantaggiati
The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.
En Yin Lai; Thu Le; Ping Li; Zaiming Luo; Maristela Lika Onozato; Fredrik Palm; Mark T Quinn; Earl H Rudolph; Glenn Solis; William J Welch; Anton Wellstein; Shakil Aslam; Kathy K Griendling; Pedro Jose; Christopher S Wilcox
Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.

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2012: Olga Catalina Rodriguez; Eveline E Vietsch; Anton Wellstein; Chris Albanese; Jill Bargonetti; Jason Catania; Sujatra Choudhury; Vamsi Kolukula; Anju Preet; Katherine Reynoso; Maria Laura Avantaggiati
Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy.
Cell cycle (Georgetown, Tex.) 2012;11(23):4436-46.
2012: Olga Catalina-Rodriguez; Amato J Giaccia; Eric Glasgow; Vamsi K Kolukula; Ferdinando Palmieri; Anju Preet; York Tomita; Anton Wellstein; Chris Albanese; Stephen Byers; Maria Laura Avantaggiati
The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.
Oncotarget 2012;3(10):1220-35.
2012: En Yin Lai; Thu Le; Ping Li; Zaiming Luo; Maristela Lika Onozato; Fredrik Palm; Mark T Quinn; Earl H Rudolph; Glenn Solis; William J Welch; Anton Wellstein; Shakil Aslam; Kathy K Griendling; Pedro Jose; Christopher S Wilcox
Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.
American journal of physiology. Renal physiology 2012;303(1):F64-74.
2012: Maram Al-Otaiby; Tabari Baker; Chris D Chien; Mary Furlong; Anna T Riegel; Armando Ganoza Salas; Richard Schlegel; Marcel O Schmidt; Elena Tassi; Jianming Xu; Anton Wellstein
Role of the nuclear receptor coactivator AIB1/SRC-3 in angiogenesis and wound healing.
The American journal of pathology 2012;180(4):1474-84.
2012: En Yin Lai; Zaiming Luo; Kathryn Sandberg; Glenn Solis; William J Welch; Anton Wellstein; Mattias Carlstrom; Steven Holland; Christopher S Wilcox
p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.
Hypertension 2012;59(2):415-20.
2012: Anton Wellstein
ALK receptor activation, ligands and therapeutic targeting in glioblastoma and in other cancers.
Frontiers in oncology 2012;2():192.
2011: Elena Tassi; Jason U Tilan; William J Welch; Christopher S Wilcox; G Ian Gallicano; Krissa A Gibby; Michael D Johnson; Sung E Kim; David P Kodack; Kevin McDonnell; Anna T Riegel; Marcel O Schmidt; Ghada M Sharif; Anton Wellstein
Impact of fibroblast growth factor-binding protein-1 expression on angiogenesis and wound healing.
The American journal of pathology 2011;179(5):2220-32.
2011: En Yin Lai; William J Welch; Anton Wellstein; Christopher S Wilcox
Superoxide modulates myogenic contractions of mouse afferent arterioles.
Hypertension 2011;58(4):650-6.
2011: Christopher D Chien; Alexander Kirilyuk; Tyler Lahusen; Jordan V Li; Annabell S Oh; Marcel O Schmidt; Anton Wellstein; Wentao Zhang; Anna T Riegel
Role of the nuclear receptor coactivator AIB1-Delta4 splice variant in the control of gene transcription.
The Journal of biological chemistry 2011;286(30):26813-27.
2011: Anton Wellstein; Jeffrey A Toretsky
Hunting ALK to feed targeted cancer therapy.
Nature medicine 2011;17(3):290-1.
2011: Joseph J LaConti; John L Marshall; Ivana Peran; Anju Preet; Anna T Riegel; Narayan Shivapurkar; Anne Deslattes Mays; Sung Eun Kim; Anton Wellstein
Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer.
PloS one 2011;6(6):e20687.
2011: Zhang-Zhi Hu; Hongzhan Huang; V Craig Jordan; Benjamin L Kagan; Jordan V Li; Anna T Riegel; Dean S Rosenthal; Cathy Wu; Lihua Zhang; Eric A Ariazi; Anton Wellstein
Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells.
PloS one 2011;6(6):e20410.
2011: Zhang-Zhi Hu; Hongzhan Huang; Cathy H Wu; Mira Jung; Anatoly Dritschilo; Anna T Riegel; Anton Wellstein
Omics-based molecular target and biomarker identification.
Methods in molecular biology (Clifton, N.J.) 2011;719():547-71.
2009: D C Stylianou; A Auf der Maur; D P Kodack; R T Henke; S Hohn; Jeffrey A Toretsky; Anna T Riegel; Anton Wellstein
Effect of single-chain antibody targeting of the ligand-binding domain in the anaplastic lymphoma kinase receptor.
Oncogene 2009;28(37):3296-306.
2009: Tyler Lahusen; Ralf T Henke; Benjamin L Kagan; Anton Wellstein; Anna T Riegel
The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer.
Breast cancer research and treatment 2009;116(2):225-37.
2009: Krissa A Gibby; Kevin McDonnell; Marcel O Schmidt; Anton Wellstein
A distinct role for secreted fibroblast growth factor-binding proteins in development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(21):8585-90.
2008: Alessia Bachis; Alessandra Mallei; Maria Idalia Cruz; Anton Wellstein; Italo Mocchetti
Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons.
Neuropharmacology 2008;55(7):1114-20.
2008: Annabell S Oh; John T Lahusen; Christopher D Chien; Mark P Fereshteh; Xiaolong Zhang; Sivanesan Dakshanamurthy; Jianming Xu; Benjamin L Kagan; Anton Wellstein; Anna T Riegel
Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.
Molecular and cellular biology 2008;28(21):6580-93.
2008: Wentao Zhang; Yifan Chen; Matthew R Swift; Elena Tassi; Dora C Stylianou; Krissa A Gibby; Anna T Riegel; Anton Wellstein
Effect of FGF-binding protein 3 on vascular permeability.
The Journal of biological chemistry 2008;283(42):28329-37.
2008: Mark P Fereshteh; Maddalena T Tilli; Sung Eun Kim; Jianming Xu; Bert W O'Malley; Anton Wellstein; Priscilla A Furth; Anna T Riegel
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.
Cancer research 2008;68(10):3697-706.
2007: Tyler Lahusen; Mark Fereshteh; Annabell S Oh; Anton Wellstein; Anna T Riegel
Epidermal growth factor receptor tyrosine phosphorylation and signaling controlled by a nuclear receptor coactivator, amplified in breast cancer 1.
Cancer research 2007;67(15):7256-65.
2007: Elena Tassi; Sharon Walter; Achim Aigner; Rafael Cabal-Manzano; Ranjan Ray; Paul J Reier; Anton Wellstein
Effects on neurite outgrowth and cell survival of a secreted fibroblast growth factor binding protein upregulated during spinal cord injury.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(2):R775-83.
2007: Angera H Kuo; Gerald E Stoica; Anna T Riegel; Anton Wellstein
Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase.
Oncogene 2007;26(6):859-69.
2006: Elena Tassi; Anton Wellstein
Tumor angiogenesis: initiation and targeting - therapeutic targeting of an FGF-binding protein, an angiogenic switch molecule, and indicator of early stages of gastrointestinal adenocarcinomas -.
Cancer research and treatment : official journal of Korean Cancer Association 2006;38(4):189-97.
2006: Elena Tassi; Anton Wellstein
The angiogenic switch molecule, secreted FGF-binding protein, an indicator of early stages of pancreatic and colorectal adenocarcinoma.
Seminars in oncology 2006;33(6 Suppl 11):S50-6.
2006: Aparna Mani; Annabell S Oh; Emma T Bowden; Tyler Lahusen; Kevin L Lorick; Allan M Weissman; Richard Schlegel; Anton Wellstein; Anna T Riegel
E6AP mediates regulated proteasomal degradation of the nuclear receptor coactivator amplified in breast cancer 1 in immortalized cells.
Cancer research 2006;66(17):8680-6.
2006: Ralf T Henke; Sung Eun Kim; Anirban Maitra; Soonmyung Paik; Anton Wellstein
Expression analysis of mRNA in formalin-fixed, paraffin-embedded archival tissues by mRNA in situ hybridization.
Methods (San Diego, Calif.) 2006;38(4):253-62.
2006: Paul Modlinger; Tina Chabrashvili; pritmohinder Gill; Margarida Mendonca; David G Harrison; Kathy K Griendling; Min Li; Julie Raggio; Anton Wellstein; Yifan Chen; William J Welch; Christopher Wilcox
RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response.
Hypertension 2006;47(2):238-44.
2006: Elena Tassi; Ralf T Henke; Emma T Bowden; Matthew R Swift; David P Kodack; Angera H Kuo; Anirban Maitra; Anton Wellstein
Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon.
Cancer research 2006;66(2):1191-8.
2006: Bin Xie; Elena Tassi; Matthew R Swift; Kevin McDonnell; Emma T Bowden; Shaomeng Wang; Yumi Ueda; York Tomita; Anna T Riegel; Anton Wellstein
Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display.
The Journal of biological chemistry 2006;281(2):1137-44.
2006: Patricio E Ray; Elena Tassi; Xue-Hui Liu; Anton Wellstein
Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(1):R105-13.
2005: Kevin McDonnell; Emma T Bowden; Rafael Cabal-Manzano; Becky Hoxter; Anna T Riegel; Anton Wellstein
Vascular leakage in chick embryos after expression of a secreted binding protein for fibroblast growth factors.
Laboratory investigation; a journal of technical methods and pathology 2005;85(6):747-55.
2005: Gerald E Stoica; Thomas F Franke; Anton Wellstein; Elisha Morgan; Frank Czubayko; Heinz-Joachim List; Ronald Reiter; Mary Beth Martin; Adriana Stoica
Heregulin-beta1 regulates the estrogen receptor-alpha gene expression and activity via the ErbB2/PI 3-K/Akt pathway.
Oncogene 2005;24(11):1964.
2005: Claudius Malerczyk; A M Schulte; Frank Czubayko; L Bellon; DG Macejak; Anna T Riegel; Anton Wellstein
Ribozyme targeting of the growth factor pleiotrophin in established tumors: a gene therapy approach.
Gene therapy 2005;12(4):339-46.
2005: Ralf T Henke; Anirban Maitra; Soonmyung Paik; Anton Wellstein
Gene expression analysis in sections and tissue microarrays of archival tissues by mRNA in situ hybridization.
Histology and histopathology 2005;20(1):225-37.
2004: Annabell S Oh; Heinz-Joachim List; Ronald Reiter; Aparna Mani; Ying Zhang; Edmund Gehan; Anton Wellstein; Anna T Riegel
The nuclear receptor coactivator AIB1 mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells.
Cancer research 2004;64(22):8299-308.
2004: Ralf T Henke; Bassem R Haddad; Sung Eun Kim; Janice D Rone; Aparna Mani; J Milburn Jessup; Anton Wellstein; Anirban Maitra; Anna T Riegel
Overexpression of the nuclear receptor coactivator AIB1 (SRC-3) during progression of pancreatic adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(18 Pt 1):6134-42.
2004: Andreas Kurtz; Achim Aigner; Rafael Cabal-Manzano; Robert E Butler; Dozier R Hood; Roy B Sessions; Frank Czubayko; Anton Wellstein
Differential regulation of a fibroblast growth factor-binding protein during skin carcinogenesis and wound healing.
Neoplasia (New York, N.Y.) 2004;6(5):595-602.
2004: Peter Burbelo; Anton Wellstein; Richard G Pestell
Altered Rho GTPase signaling pathways in breast cancer cells.
Breast cancer research and treatment 2004;84(1):43-8.
2004: Karen Beagles; Anton Wellstein; Barbara Bayer
Systemic morphine administration suppresses genes involved in antigen presentation.
Molecular pharmacology 2004;65(2):437-42.
2004: Ronald Reiter; Annabell S Oh; Anton Wellstein; Anna T Riegel
Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity.
Oncogene 2004;23(2):403-9.
2003: Ranjan Ray; Rafael Cabal-Manzano; Amy R Moser; Todd Waldman; Laurie M Zipper; Achim Aigner; Stephen W Byers; Anna T Riegel; Anton Wellstein
Up-regulation of fibroblast growth factor-binding protein, by beta-catenin during colon carcinogenesis.
Cancer research 2003;63(23):8085-9.
2003: Gerald E Stoica; Thomas F Franke; Maria Moroni; Susette Mueller; Elisha Morgan; Mary C Iann; Abigail D Winder; Ronald Reiter; Anton Wellstein; Mary Beth Martin; Adriana Stoica
Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.
Oncogene 2003;22(39):7998-8011.
2003: Gerald E Stoica; Thomas F Franke; Anton Wellstein; Frank Czubayko; Heinz-Joachim List; Ronald Reiter; Elisha Morgan; Mary Beth Martin; Adriana Stoica
Estradiol rapidly activates Akt via the ErbB2 signaling pathway.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):818-30.
2003: Gerald E Stoica; Thomas F Franke; Anton Wellstein; Elisha Morgan; Frank Czubayko; Heinz-Joachim List; Ronald Reiter; Mary Beth Martin; Adriana Stoica
Heregulin-beta1 regulates the estrogen receptor-alpha gene expression and activity via the ErbB2/PI 3-K/Akt pathway.
Oncogene 2003;22(14):2073-87.
2003: Benjamin L Kagan; Ralf T Henke; Rafael Cabal-Manzano; Gerald E Stoica; Quang Nguyen; Anton Wellstein; Anna T Riegel
Complex regulation of the fibroblast growth factor-binding protein in MDA- MB-468 breast cancer cells by CCAAT/enhancer-binding protein beta.
Cancer research 2003;63(7):1696-705.
2002: Kristina J Lauritsen; Heinz-Joachim List; Ronald Reiter; Anton Wellstein; Anna T Riegel
A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells.
Oncogene 2002;21(47):7147-55.
2002: Gerald E Stoica; Alice Kuo; Ciaran Powers; Emma T Bowden; Elaine Buchert Sale; Anna T Riegel; Anton Wellstein
Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types.
The Journal of biological chemistry 2002;277(39):35990-8.
2002: Emma T Bowden; Gerald E Stoica; Anton Wellstein
Anti-apoptotic signaling of pleiotrophin through its receptor, anaplastic lymphoma kinase.
The Journal of biological chemistry 2002;277(39):35862-8.
2002: Ciaran Powers; Achim Aigner; Gerald E Stoica; Kevin McDonnell; Anton Wellstein
Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth.
The Journal of biological chemistry 2002;277(16):14153-8.
2002: Robert Jäger; B List; Cornelius Knabbe; Boussad Souttou; Daniel Raulais; Thomas Zeiler; Anton Wellstein; Achim Aigner; Andreas Neubauer; Gerhard Zugmaier
Serum levels of the angiogenic factor pleiotrophin in relation to disease stage in lung cancer patients.
British journal of cancer 2002;86(6):858-63.
2002: Hans-Jürgen Klomp; Oliver Zernial; Sabine Flachmann; Anton Wellstein; Hartmut Juhl
Significance of the expression of the growth factor pleiotrophin in pancreatic cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):823-7.
2002: Achim Aigner; Patricio E Ray; Frank Czubayko; Anton Wellstein
Immunolocalization of an FGF-binding protein reveals a widespread expression pattern during different stages of mouse embryo development.
Histochemistry and cell biology 2002;117(1):1-11.
2001: Elena Tassi; Ali Al-Attar; Achim Aigner; Matthew R Swift; Kevin McDonnell; A Karavanov; Anton Wellstein
Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein.
The Journal of biological chemistry 2001;276(43):40247-53.
2001: Ronald Reiter; Anton Wellstein; Anna T Riegel
An isoform of the coactivator AIB1 that increases hormone and growth factor sensitivity is overexpressed in breast cancer.
The Journal of biological chemistry 2001;276(43):39736-41.
2001: Heinz-Joachim List; Ronald Reiter; Baljit Singh; Anton Wellstein; Anna T Riegel
Expression of the nuclear coactivator AIB1 in normal and malignant breast tissue.
Breast cancer research and treatment 2001;68(1):21-8.
2001: Heinz-Joachim List; K J Lauritsen; Ronald Reiter; Ciaran Powers; Anton Wellstein; Anna T Riegel
Ribozyme targeting demonstrates that the nuclear receptor coactivator AIB1 is a rate-limiting factor for estrogen-dependent growth of human MCF-7 breast cancer cells.
The Journal of biological chemistry 2001;276(26):23763-8.
2001: Gerald E Stoica; Alice Kuo; Achim Aigner; Iruvanti Sunitha; Boussad Souttou; Claudius Malerczyk; DJ Caughey; D Wen; A Karavanov; Anna T Riegel; Anton Wellstein
Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin.
The Journal of biological chemistry 2001;276(20):16772-9.
2001: Achim Aigner; M Butscheid; Philip Kunkel; E Krause; Katrin Lamszus; Anton Wellstein; Frank Czubayko
An FGF-binding protein (FGF-BP) exerts its biological function by parallel paracrine stimulation of tumor cell and endothelial cell proliferation through FGF-2 release.
International journal of cancer. Journal international du cancer 2001;92(4):510-7.
2001: Xue-Hui Liu; Achim Aigner; Anton Wellstein; Patricio E Ray
Up-regulation of a fibroblast growth factor binding protein in children with renal diseases.
Kidney international 2001;59(5):1717-28.
2001: VK Harris; Benjamin L Kagan; R Ray; Christine M Coticchia; ED Liaudet-Coopman; Anton Wellstein; A Tate Riegel
Serum induction of the fibroblast growth factor-binding protein (FGF-BP) is mediated through ERK and p38 MAP kinase activation and C/EBP-regulated transcription.
Oncogene 2001;20(14):1730-8.
2001: MK Yunmbam; Anton Wellstein
The bacterial polysaccharide tecogalan blocks growth of breast cancer cells in vivo.
Oncology reports 2001;8(1):161-4.
2000: B J Boyle; VK Harris; ED Liaudet-Coopman; Anna T Riegel; Anton Wellstein
Differential regulation of a fibroblast growth factor-binding protein by receptor-selective analogs of retinoic acid.
Biochemical pharmacology 2000;60(11):1677-84.
2000: D Weber; Hans-Jürgen Klomp; Frank Czubayko; Anton Wellstein; Hartmut Juhl
Pleiotrophin can be rate-limiting for pancreatic cancer cell growth.
Cancer research 2000;60(18):5284-8.
2000: VK Harris; Christine M Coticchia; Heinz-Joachim List; Anton Wellstein; Anna T Riegel
Mitogen-induced expression of the fibroblast growth factor-binding protein is transcriptionally repressed through a non-canonical E-box element.
The Journal of biological chemistry 2000;275(37):28539-48.
2000: C J Powers; Sandra W McLeskey; Anton Wellstein
Fibroblast growth factors, their receptors and signaling.
Endocrine-related cancer 2000;7(3):165-97.
2000: A M Schulte; Claudius Malerczyk; Rafael Cabal-Manzano; J J Gajarsa; Heinz-Joachim List; Anna T Riegel; Anton Wellstein
Influence of the human endogenous retrovirus-like element HERV-E.PTN on the expression of growth factor pleiotrophin: a critical role of a retroviral Sp1-binding site.
Oncogene 2000;19(35):3988-98.
2000: VK Harris; Christine M Coticchia; Benjamin L Kagan; S Ahmad; Anton Wellstein; Anna T Riegel
Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways.
The Journal of biological chemistry 2000;275(15):10802-11.
2000: Achim Aigner; Claudius Malerczyk; Richard A Houghtling; Anton Wellstein
Tissue distribution and retinoid-mediated downregulation of an FGF-binding protein (FGF-BP) in the rat.
Growth factors (Chur, Switzerland) 2000;18(1):51-62.
1999: George A Mashour; HL Wang; Rafael Cabal-Manzano; Anton Wellstein; Robert L Martuza; Andreas Kurtz
Aberrant cutaneous expression of the angiogenic factor midkine is associated with neurofibromatosis type-1.
The Journal of investigative dermatology 1999;113(3):398-402.
1999: Heinz-Joachim List; C Lozano; Jianming Lu; Mark Danielsen; Anton Wellstein; Anna T Riegel
Comparison of chromatin remodeling and transcriptional activation of the mouse mammary tumor virus promoter by the androgen and glucocorticoid receptor.
Experimental cell research 1999;250(2):414-22.
1998: Boussad Souttou; Hartmut Juhl; J Hackenbruck; M Röckseisen; Hans-Jürgen Klomp; Daniel Raulais; Marc Vigny; Anton Wellstein
Relationship between serum concentrations of the growth factor pleiotrophin and pleiotrophin-positive tumors.
Journal of the National Cancer Institute 1998;90(19):1468-73.
1998: VK Harris; ED Liaudet-Coopman; B J Boyle; Anton Wellstein; Anna T Riegel
Phorbol ester-induced transcription of a fibroblast growth factor-binding protein is modulated by a complex interplay of positive and negative regulatory promoter elements.
The Journal of biological chemistry 1998;273(30):19130-9.
1998: A M Schulte; Anton Wellstein
Structure and phylogenetic analysis of an endogenous retrovirus inserted into the human growth factor gene pleiotrophin.
Journal of virology 1998;72(7):6065-72.
1998: Andreas Kurtz; E Spitzer; W Zschiesche; Anton Wellstein; R Grosse
Local control of mammary gland differentiation: mammary-derived growth inhibitor and pleiotrophin.
Biochemical Society symposium 1998;63():51-69.
1997: John L Marshall; Anton Wellstein; James M Rae; R J DeLap; K Phipps; John Hanfelt; MK Yunmbam; J X Sun; K L Duchin; Michael J Hawkins
Phase I trial of orally administered pentosan polysulfate in patients with advanced cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 1):2347-54.
1997: Hartmut Juhl; S G Downing; Anton Wellstein; Frank Czubayko
HER-2/neu is rate-limiting for ovarian cancer growth. Conditional depletion of HER-2/neu by ribozyme targeting.
The Journal of biological chemistry 1997;272(47):29482-6.
1997: Frank Czubayko; ED Liaudet-Coopman; Achim Aigner; A T Tuveson; Guy Berchem; Anton Wellstein
A secreted FGF-binding protein can serve as the angiogenic switch in human cancer.
Nature medicine 1997;3(10):1137-40.
1997: Frank Czubayko; S G Downing; SS Hsieh; D J Goldstein; P Y Lu; B C Trapnell; Anton Wellstein
Adenovirus-mediated transduction of ribozymes abrogates HER-2/neu and pleiotrophin expression and inhibits tumor cell proliferation.
Gene therapy 1997;4(9):943-9.
1997: RL Meighan-Mantha; Anton Wellstein; Anna T Riegel
Differential regulation of extracellular signal-regulated kinase 1 and 2 activity during 12-O-tetradecanoylphorbol 13-acetate-induced differentiation of HL-60 cells.
Experimental cell research 1997;234(2):321-8.
1997: Boussad Souttou; S Ahmad; Anna T Riegel; Anton Wellstein
Signal transduction pathways involved in the mitogenic activity of pleiotrophin. Implication of mitogen-activated protein kinase and phosphoinositide 3-kinase pathways.
The Journal of biological chemistry 1997;272(31):19588-93.
1997: Andreas Kurtz; HL Wang; N Darwiche; VK Harris; Anton Wellstein
Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis.
Oncogene 1997;14(22):2671-81.
1997: ED Liaudet-Coopman; Guy Berchem; Anton Wellstein
In vivo inhibition of angiogenesis and induction of apoptosis by retinoic acid in squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(2):179-84.
1996: ED Liaudet-Coopman; A M Schulte; M Cardillo; Anton Wellstein
A tetracycline-responsive promoter system reveals the role of a secreted binding protein for FGFs during the early phase of tumor growth.
Biochemical and biophysical research communications 1996;229(3):930-7.
1996: A M Schulte; S Lai; Andreas Kurtz; Frank Czubayko; Anna T Riegel; Anton Wellstein
Human trophoblast and choriocarcinoma expression of the growth factor pleiotrophin attributable to germ-line insertion of an endogenous retrovirus.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14759-64.
1996: Frank Czubayko; A M Schulte; Guy Berchem; Anton Wellstein
Melanoma angiogenesis and metastasis modulated by ribozyme targeting of the secreted growth factor pleiotrophin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14753-8.
1996: ED Liaudet-Coopman; Anton Wellstein
Regulation of gene expression of a binding protein for fibroblast growth factors by retinoic acid.
The Journal of biological chemistry 1996;271(35):21303-8.
1996: Anton Wellstein; Frank Czubayko
Inhibition of fibroblast growth factors.
Breast cancer research and treatment 1996;38(1):109-19.
1995: S Lai; A M Schulte; Anton Wellstein; Anna T Riegel
An additional 5'-upstream exon exists in the human pleiotrophin-encoding gene.
Gene 1995;153(2):301-2.
1995: Andreas Kurtz; A M Schulte; Anton Wellstein
Pleiotrophin and midkine in normal development and tumor biology.
Critical reviews in oncogenesis 1995;6(2):151-77.
1995: Frank Czubayko; A M Schulte; S C Missner; S S Hsieh; Kenneth Colley; Anton Wellstein
Molecular and pharmacologic targeting of angiogenesis factors--the example of pleiotrophin.
Breast cancer research and treatment 1995;36(2):157-68.
1995: S M Swain; B Parker; Anton Wellstein; Marc Lippman; C Steakley; R DeLap
Phase I trial of pentosan polysulfate.
Investigational new drugs 1995;13(1):55-62.
1994: Frank Czubayko; Richard V Smith; H C Chung; Anton Wellstein
Tumor growth and angiogenesis induced by a secreted binding protein for fibroblast growth factors.
The Journal of biological chemistry 1994;269(45):28243-8.
1994: Frank Czubayko; Anna T Riegel; Anton Wellstein
Ribozyme-targeting elucidates a direct role of pleiotrophin in tumor growth.
The Journal of biological chemistry 1994;269(33):21358-63.
1994: Anna T Riegel; Anton Wellstein
The potential role of the heparin-binding growth factor pleiotrophin in breast cancer.
Breast cancer research and treatment 1994;31(2-3):309-14.
1994: Anton Wellstein
Growth factor targeted and conventional therapy of breast cancer.
Breast cancer research and treatment 1994;31(2-3):141-51.
1993: S Swain; Anton Wellstein; B Parker; Marc Lippman; C Steakley; R DeLap
Heparin-binding growth factor blockade with pentosan polysulfate.
Annals of the New York Academy of Sciences 1993;698():63-70.
1993: A F Dobrenski; A S Zeft; Anton Wellstein; Anna T Riegel
DNA binding of the transcription factor PO-B is regulated during differentiation of HL-60 cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(8):647-56.
1993: B W Parker; S M Swain; Gerhard Zugmaier; R L DeLap; Marc Lippman; Anton Wellstein
Detectable inhibition of heparin-binding growth factor activity in sera from patients treated with pentosan polysulfate.
Journal of the National Cancer Institute 1993;85(13):1068-73.
1992: W Fang; N Hartmann; D T Chow; Anna T Riegel; Anton Wellstein
Pleiotrophin stimulates fibroblasts and endothelial and epithelial cells and is expressed in human cancer.
The Journal of biological chemistry 1992;267(36):25889-97.
1992: Gerhard Zugmaier; Marc Lippman; Anton Wellstein
Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from tumor cells and blockage by PPS of tumor growth in animals.
Journal of the National Cancer Institute 1992;84(22):1716-24.
1992: S Lai; Frank Czubayko; Anna T Riegel; Anton Wellstein
Structure of the human heparin-binding growth factor gene pleiotrophin.
Biochemical and biophysical research communications 1992;187(2):1113-22.
1992: R Lupu; Anton Wellstein; J Sheridan; B W Ennis; Gerhard Zugmaier; D Katz; Marc Lippman; Robert B Dickson
Purification and characterization of a novel growth factor from human breast cancer cells.
Biochemistry 1992;31(32):7330-40.
1992: Anton Wellstein; W J Fang; A Khatri; Y Lu; S S Swain; Robert B Dickson; J Sasse; Anna T Riegel; Marc Lippman
A heparin-binding growth factor secreted from breast cancer cells homologous to a developmentally regulated cytokine.
The Journal of biological chemistry 1992;267(4):2582-7.
1991: Anton Wellstein; A F Dobrenski; M N Radonovich; J F Brady; Anna T Riegel
Purification of PO-B, a protein that has increased affinity for the pro-opiomelanocortin gene promoter after dephosphorylation.
The Journal of biological chemistry 1991;266(19):12234-41.
1991: Anton Wellstein; Gerhard Zugmaier; J A Califano; F Kern; Soonmyung Paik; Marc Lippman
Tumor growth dependent on Kaposi's sarcoma-derived fibroblast growth factor inhibited by pentosan polysulfate.
Journal of the National Cancer Institute 1991;83(10):716-20.
1990: Anton Wellstein; R Lupu; Gerhard Zugmaier; S L Flamm; A L Cheville; P Delli Bovi; Claudio Basilico; Marc Lippman; FG Kern
Autocrine growth stimulation by secreted Kaposi fibroblast growth factor but not by endogenous basic fibroblast growth factor.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(2):63-71.