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Nils Welsh

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Anatomy

Chemicals & Drugs

Living Beings

Disorders

Type 1 Diabetes Mellitus

Physiology

Transfection

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Co-Publications
Name
34
Sandler, Stellan
27
Eizirik, Decio
25
Welsh, Michael
13
Saldeen, Johan
12
Hellerström, Claes
8
Berggren, Per-Olof
8
Tillmar, Linda
7
Mokhtari, Dariush
7
Barbu, Andreea
6
Jansson, Leif
6
Makeeva, Natalia
5
Myers, Jason
5
Hägerkvist, Robert
4
Eriksson, Ulf
4
Flodström, M

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Publications

TOP 3
Mokhtari Dariush; Welsh Nils
Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes.
Mokhtari Dariush; Kerblom Björn; Mehmeti Ilir; Wang Xuan; Funa Nina S; Olerud Johan; Lenzen Sigurd; Welsh Nils; Welsh Michael
Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice.
Sandler Stellan; Andersson Annika K; Larsson Jenny; Makeeva Natalia; Olsen Therese; Arkhammar Per O G; Hansen John Bondo; Karlsson F Anders; Welsh Nils
Possible role of an ischemic preconditioning-like response mechanism in K(ATP) channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function.

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All Publications

2010: Mokhtari Dariush; Welsh Nils
Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes.
Clinical science (London, England : 1979) 2010;118(4):241-7.
2009: Mokhtari Dariush; Kerblom Björn; Mehmeti Ilir; Wang Xuan; Funa Nina S; Olerud Johan; Lenzen Sigurd; Welsh Nils; Welsh Michael
Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice.
Biochemical and biophysical research communications 2009;387(3):553-7.
2008: Sandler Stellan; Andersson Annika K; Larsson Jenny; Makeeva Natalia; Olsen Therese; Arkhammar Per O G; Hansen John Bondo; Karlsson F Anders; Welsh Nils
Possible role of an ischemic preconditioning-like response mechanism in K(ATP) channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function.
Biochemical pharmacology 2008;76(12):1748-56.
2008: Olerud Johan; Johansson Magnus; Lawler Jack; Welsh Nils; Carlsson Per-Ola
Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets.
Diabetes 2008;57(7):1870-7.
2008: Mokhtari Dariush; Myers Jason W; Welsh Nils
MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells.
Diabetes 2008;57(7):1896-904.
2008: Mokhtari Dariush; Myers Jason W; Welsh Nils
The MAPK kinase kinase-1 is essential for stress-induced pancreatic islet cell death.
Endocrinology 2008;149(6):3046-53.
2008: Makeeva Natalia; Roomans Godfried M; Myers Jason W; Welsh Nils
Transforming growth factor-beta-activated protein kinase 1-binding protein (TAB)-1alpha, but not TAB1beta, mediates cytokine-induced p38 mitogen-activated protein kinase phosphorylation and cell death in insulin-producing cells.
Endocrinology 2008;149(1):302-9.
2008: Hägerkvist Robert; Jansson Leif; Welsh Nils
Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet.
Clinical science (London, England : 1979) 2008;114(1):65-71.
2007: Andersson A; Eriksson U J; Jansson L; Sandler S; Welsh M; Welsh N
Claes Hellerström: a friendly islet explorer.
Diabetologia 2007;50(2):4 p following 496.
2007: Hägerkvist Robert; Sandler Stellan; Mokhtari Dariush; Welsh Nils
Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(2):618-28.
2007: Hägerkvist Robert; Mokhtari Dariush; Lindholm Cecilia; Farnebo Filip; Mostoslavsky Gustavo; Mulligan Richard C; Welsh Nils; Welsh Michael
Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli.
Experimental cell research 2007;313(2):284-91.
2007: Barbu Andreea; Welsh Nils
Lipofection of insulin-producing RINm5F cells: methodological improvements.
Journal of liposome research 2007;17(2):49-62.
2007: Makeeva Natalia; Roomans Godfried M; Welsh Nils
Role of TAB1 in nitric oxide-induced p38 activation in insulin-producing cells.
International journal of biological sciences 2007;3(2):71-6.
2006: Hägerkvist Robert; Makeeva Natalia; Elliman Stephen; Welsh Nils
Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro.
Cell biology international 2006;30(12):1013-7.
2006: Barbu A R; Bodin B; Welsh M; Jansson L; Welsh N
A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans.
Diabetologia 2006;49(10):2388-91.
2006: Fred Rickard G; Tillmar Linda; Welsh Nils
The role of PTB in insulin mRNA stability control.
Current diabetes reviews 2006;2(3):363-6.
2006: Makeeva Natalia; Myers Jason W; Welsh Nils
Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells.
The Biochemical journal 2006;393(Pt 1):129-39.
2005: Cnop Miriam; Welsh Nils; Jonas Jean-Christophe; Jörns Anne; Lenzen Sigurd; Eizirik Decio L
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.
Diabetes 2005;54 Suppl 2():S97-107.
2005: Welsh Nils; Cnop Miriam; Kharroubi Ilham; Bugliani Marco; Lupi Roberto; Marchetti Piero; Eizirik Décio L
Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?
Diabetes 2005;54(11):3238-44.
2005: Barbu Andreea R; Akusjärvi Göran; Welsh Nils
Adenoviral-mediated transduction of human pancreatic islets: importance of adenoviral genome for cell viability and association with a deficient antiviral response.
Endocrinology 2005;146(5):2406-14.
2005: Hägerkvist Robert; Mokhtari Dariush; Myers Jason W; Tengholm Anders; Welsh Nils
siRNA produced by recombinant dicer mediates efficient gene silencing in islet cells.
Annals of the New York Academy of Sciences 2005;1040():114-22.
2005: Fred Rikard G; Welsh Nils
Increased expression of polypyrimidine tract binding protein results in higher insulin mRNA levels.
Biochemical and biophysical research communications 2005;328(1):38-42.
2004: Barbu A; Welsh N
The use of tetrazolium salt-based methods for determination of islet cell viability in response to cytokines: a cautionary note.
Diabetologia 2004;47(11):2042-3.
2004: Tillmar Linda; Welsh Nils
Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3'-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin.
Molecular and cellular biochemistry 2004;260(1-2):85-90.
2004: Tillmar Linda; Welsh Nils
In vitro cultured rat islets express genes that both prevent and promote angiogenesis.
JOP : Journal of the pancreas 2004;5(2):81-91.
2004: Saldeen Johan; Welsh Nils
p38 MAPK inhibits JNK2 and mediates cytokine-activated iNOS induction and apoptosis independently of NF-KB translocation in insulin-producing cells.
European cytokine network 2004;15(1):47-52.
2004: Andersson Arne; Carlsson Per-Ola; Carlsson Carina; Olsson Richard; Nordin Astrid; Johansson Magnus; Palm Fredrik; Tyrberg Björn; Källskog Orjan; Tillmar Linda; Welsh Nils; Mattsson Göran; Jansson Leif
Promoting islet cell function after transplantation.
Cell biochemistry and biophysics 2004;40(3 Suppl):55-64.
2003: Kullin M; Li Z; Bondo Hansen J; Welsh N; Karlsson F A; Sandler S
Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1beta mediated suppression--possible involvement of the mitochondrial membrane potential.
Diabetologia 2003;46(1):80-8.
2003: Saldeen Johan; Tillmar Linda; Karlsson Ella; Welsh Nils
Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis.
Molecular and cellular biochemistry 2003;243(1-2):113-22.
2002: Barbu Andreea R; Akusjärvi Goran; Welsh Nils
Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression.
Molecular medicine (Cambridge, Mass.) 2002;8(11):733-41.
2002: Welsh Nils; Makeeva Natalia; Welsh Michael
Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
Molecular medicine (Cambridge, Mass.) 2002;8(11):695-704.
2002: Tillmar Linda; Welsh Nils
Hypoxia may increase rat insulin mRNA levels by promoting binding of the polypyrimidine tract-binding protein (PTB) to the pyrimidine-rich insulin mRNA 3'-untranslated region.
Molecular medicine (Cambridge, Mass.) 2002;8(5):263-72.
2002: Barbu Andreea; Welsh Nils; Saldeen Johan
Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Deltapsi(m)) in pancreatic RINm5F cells: prevention by Bcl-2.
Molecular and cellular endocrinology 2002;190(1-2):75-82.
2002: Tillmar Linda; Carlsson Carina; Welsh Nils
Control of insulin mRNA stability in rat pancreatic islets. Regulatory role of a 3'-untranslated region pyrimidine-rich sequence.
The Journal of biological chemistry 2002;277(2):1099-106.
2001: Saldeen J; Lee J C; Welsh N
Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis.
Biochemical pharmacology 2001;61(12):1561-9.
2000: Saldeen J; Jaffrézou J P; Welsh N
The acid sphingomyelinase inhibitor SR33557 counteracts TNF-alpha-mediated potentiation of IL-1beta-induced NF-kappaB activation in the insulin-producing cell line Rinm5F.
Autoimmunity 2000;32(4):241-54.
2000: Saldeen J; Sandler S; Bendtzen K; Welsh N
Liposome-mediated transfer of IL-1 receptor antagonist gene to dispersed islet cells does not prevent recurrence of disease in syngeneically transplanted NOD mice.
Cytokine 2000;12(4):405-8.
2000: Sandler S; Andersson A K; Barbu A; Hellerström C; Holstad M; Karlsson E; Sandberg J O; Strandell E; Saldeen J; Sternesjö J; Tillmar L; Eizirik D L; Flodström M; Welsh N
Novel experimental strategies to prevent the development of type 1 diabetes mellitus.
Upsala journal of medical sciences 2000;105(2):17-34.
1999: Welsh N
Gene therapy in diabetes mellitus: promises and piffalls.
Current opinion in molecular therapeutics 1999;1(4):464-70.
1999: Carlsson C; Borg L A; Welsh N
Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro.
Endocrinology 1999;140(8):3422-8.
1999: Wentzel P; Welsh N; Eriksson U J
Developmental damage, increased lipid peroxidation, diminished cyclooxygenase-2 gene expression, and lowered prostaglandin E2 levels in rat embryos exposed to a diabetic environment.
Diabetes 1999;48(4):813-20.
1999: Welsh M; Christmansson L; Karlsson T; Sandler S; Welsh N
Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.
Molecular medicine (Cambridge, Mass.) 1999;5(3):169-80.
1998: Ingelsson E; Saldeen J; Welsh N
Islet expression of perforin, Fas/Apo-1 and interleukin-1 converting enzyme (ICE) in non-obese diabetic (NOD) mice.
Immunology letters 1998;63(3):125-9.
1998: Forsberg H; Eriksson U J; Welsh N
Apoptosis in embryos of diabetic rats.
Pharmacology & toxicology 1998;83(3):104-11.
1998: Saldeen J; Welsh N
Nicotinamide-induced apoptosis in insulin producing cells is associated with cleavage of poly(ADP-ribose) polymerase.
Molecular and cellular endocrinology 1998;139(1-2):99-107.
1998: Forsberg H; Eriksson U J; Melefors O; Welsh N
Beta-hydroxybutyrate increases reactive oxygen species in late but not in early postimplantation embryonic cells in vitro.
Diabetes 1998;47(2):255-62.
1997: Sternesjö J; Welsh N; Sandler S
S-methyl-L-thiocitrulline counteracts interleukin 1 beta induced suppression of pancreatic islet function in vitro, but does not protect against multiple low-dose streptozotocin-induced diabetes in vivo.
Cytokine 1997;9(5):352-9.
1996: Saldeen J; Curiel D T; Eizirik D L; Andersson A; Strandell E; Buschard K; Welsh N
Efficient gene transfer to dispersed human pancreatic islet cells in vitro using adenovirus-polylysine/DNA complexes or polycationic liposomes.
Diabetes 1996;45(9):1197-203.
1996: Eizirik D L; Flodström M; Karlsen A E; Welsh N
The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells.
Diabetologia 1996;39(8):875-90.
1996: Flodström M; Welsh N; Eizirik D L
Cytokines activate the nuclear factor kappa B (NF-kappa B) and induce nitric oxide production in human pancreatic islets.
FEBS letters 1996;385(1-2):4-6.
1996: Welsh N
Interleukin-1 beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F.
The Journal of biological chemistry 1996;271(14):8307-12.
1995: Strandell E; Buschard K; Saldeen J; Welsh N
Interleukin-1 beta induces the expression of hsp70, heme oxygenase and Mn-SOD in FACS-purified rat islet beta-cells, but not in alpha-cells.
Immunology letters 1995;48(2):145-8.
1995: Welsh N; Margulis B; Borg L A; Wiklund H J; Saldeen J; Flodström M; Mello M A; Andersson A; Pipeleers D G; Hellerström C
Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus.
Molecular medicine (Cambridge, Mass.) 1995;1(7):806-20.
1995: Eizirik D L; Sandler S; Welsh N; Juntti-Berggren L; Berggren P O
Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation.
Molecular and cellular endocrinology 1995;111(2):159-65.
1995: Welsh N; Bendtzen K; Welsh M
Expression of an insulin/interleukin-1 receptor antagonist hybrid gene in insulin-producing cell lines (HIT-T15 and NIT-1) confers resistance against interleukin-1-induced nitric oxide production.
The Journal of clinical investigation 1995;95(4):1717-22.
1995: Welsh M; Welsh N; Bendtzen K; Mares J; Strandell E; Oberg C; Sandler S
Comparison of mRNA contents of interleukin-1 beta and nitric oxide synthase in pancreatic islets isolated from female and male nonobese diabetic mice.
Diabetologia 1995;38(2):153-60.
1994: Welsh N; Margulis B; Bendtzen K; Sandler S
Liposomal delivery of antioxidant enzymes protects against hydrogen peroxide- but not interleukin-1 beta-induced inhibition of glucose metabolism in rat pancreatic islets.
The Journal of endocrinology 1994;143(1):151-6.
1994: Eizirik D L; Welsh N; Sener A; Malaisse W J
Protective action of succinic acid monomethyl ester against the impairment of glucose-stimulated insulin release caused by glucopenia or starvation: metabolic determinants.
Biochemical medicine and metabolic biology 1994;53(1):34-45.
1994: Eizirik D L; Pipeleers D G; Ling Z; Welsh N; Hellerström C; Andersson A
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9253-6.
1994: Saldeen J; Welsh N
Interleukin-1 beta induced activation of NF-kappa B in insulin producing RINm5F cells is prevented by the protease inhibitor N alpha-p-tosyl-L-lysine chloromethylketone.
Biochemical and biophysical research communications 1994;203(1):149-55.
1994: Welsh N; Sandler S
Protective action by hemin against interleukin-1 beta induced inhibition of rat pancreatic islet function.
Molecular and cellular endocrinology 1994;103(1-2):109-14.
1994: Eizirik D L; Sandler S; Welsh N; Cetkovic-Cvrlje M; Nieman A; Geller D A; Pipeleers D G; Bendtzen K; Hellerström C
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation.
The Journal of clinical investigation 1994;93(5):1968-74.
1994: Sandler S; Eizirik D L; Sternesjö J; Welsh N
Role of cytokines in regulation of pancreatic B-cell function.
Biochemical Society transactions 1994;22(1):26-30.
1994: Eizirik D L; Welsh N; Niemann A; Velloso L A; Malaisse W J
Succinic acid monomethyl ester protects rat pancreatic islet secretory potential against interleukin-1 beta (IL-1 beta) without affecting glutamate decarboxylase expression or nitric oxide production.
FEBS letters 1994;337(3):298-302.
1994: Welsh N; Eizirik D L; Sandler S
Nitric oxide and pancreatic beta-cell destruction in insulin dependent diabetes mellitus: don't take NO for an answer.
Autoimmunity 1994;18(4):285-90.
1994: Eizirik D L; Sandler S; Welsh N; Bendtzen K; Hellerström C
Nicotinamide decreases nitric oxide production and partially protects human pancreatic islets against the suppressive effects of combinations of cytokines.
Autoimmunity 1994;19(3):193-8.
1993: Sjöholm A; Arkhammar P; Welsh N; Bokvist K; Rorsman P; Hallberg A; Nilsson T; Welsh M; Berggren P O
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity.
The Journal of clinical investigation 1993;92(4):1910-7.
1993: Sandler S; Welsh N
Interleukin-10 stimulates rat pancreatic islets in vitro, but fails to protect against interleukin-1.
Biochemical and biophysical research communications 1993;195(2):859-65.
1993: Eizirik D L; Björklund A; Welsh N
Interleukin-1-induced expression of nitric oxide synthase in insulin-producing cells is preceded by c-fos induction and depends on gene transcription and protein synthesis.
FEBS letters 1993;317(1-2):62-6.
1992: Sandler S; Jansson L; Welsh N
Adaptive response in beta-cell function in pancreatic islets isolated from partially pancreatectomized rats.
Molecular and cellular endocrinology 1992;86(3):149-56.
1992: Eizirik D L; Cagliero E; Björklund A; Welsh N
Interleukin-1 beta induces the expression of an isoform of nitric oxide synthase in insulin-producing cells, which is similar to that observed in activated macrophages.
FEBS letters 1992;308(3):249-52.
1992: Sandler S; Eizirik D L; Svensson C; Strandell E; Welsh M; Welsh N
[Are cytokines mediators in the development of insulin-dependent diabetes mellitus?]
Läkartidningen 1992;89(20):1777-9.
1992: Borg L A; Cagliero E; Sandler S; Welsh N; Eizirik D L
Interleukin-1 beta increases the activity of superoxide dismutase in rat pancreatic islets.
Endocrinology 1992;130(5):2851-7.
1992: Sjöholm A; Welsh N; Hellerström C
Lithium increases DNA replication, polyamine content, and insulin secretion by rat pancreatic beta-cells.
The American journal of physiology 1992;262(2 Pt 1):C391-5.
1992: Welsh N; Sandler S
Interleukin-1 beta induces nitric oxide production and inhibits the activity of aconitase without decreasing glucose oxidation rates in isolated mouse pancreatic islets.
Biochemical and biophysical research communications 1992;182(1):333-40.
1991: Welsh N; Eizirik D L; Bendtzen K; Sandler S
Interleukin-1 beta-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase.
Endocrinology 1991;129(6):3167-73.
1991: Margulis B A; Sandler S; Eizirik D L; Welsh N; Welsh M
Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function.
Diabetes 1991;40(11):1418-22.
1991: Welsh N; Pääbo S; Welsh M
Decreased mitochondrial gene expression in isolated islets of rats injected neonatally with streptozotocin.
Diabetologia 1991;34(9):626-31.
1991: Sjöholm A; Welsh N; Hoftiezer V; Bankston P W; Hellerström C
Increased glucose oxidation and contents of insulin and ATP in polyamine-depleted rat insulinoma cells (RINm5F).
The Biochemical journal 1991;277 ( Pt 2)():533-40.
1991: Svensson C; Welsh N; Krawetz S A; Welsh M
Exhibition of specific alterations in activities and mRNA levels of rat islet glycolytic and mitochondrial enzymes in three different in vitro model systems for attenuated insulin release.
Diabetes 1991;40(6):771-6.
1991: Welsh N; Oberg C; Welsh M
GTP-binding proteins may stimulate insulin biosynthesis in rat pancreatic islets by enhancing the signal-recognition-particle-dependent translocation of the insulin mRNA poly-/mono-some complex to the endoplasmic reticulum.
The Biochemical journal 1991;275 ( Pt 1)():23-8.
1991: Welsh N; Bendtzen K; Sandler S
Influence of protease on inhibitory and stimulatory effects of interleukin 1 beta on beta-cell function.
Diabetes 1991;40(2):290-4.
1991: Hellerström C; Eizirik D L; Welsh N; Sjöholm A; Jansson L; Svensson C; Strandell E; Korsgren O; Li Z Q; Andersson A
New perspectives on the structure and function of the normal and diabetic beta-cell.
Upsala journal of medical sciences 1991;96(1):1-16.
1991: Sandler S; Eizirik D L; Svensson C; Strandell E; Welsh M; Welsh N
Biochemical and molecular actions of interleukin-1 on pancreatic beta-cells.
Autoimmunity 1991;10(3):241-53.
1991: Welsh N; Welsh M; Lindquist S; Eizirik D L; Bendtzen K; Sandler S
Interleukin-1 beta increases the biosynthesis of the heat shock protein hsp70 and selectively decreases the biosynthesis of five proteins in rat pancreatic islets.
Autoimmunity 1991;9(1):33-40.
1990: Sandler S; Bendtzen K; Eizirik D L; Strandell E; Welsh M; Welsh N
Metabolism and beta-cell function of rat pancreatic islets exposed to human interleukin-1 beta in the presence of a high glucose concentration.
Immunology letters 1990;26(3):245-51.
1990: Sjöholm A; Welsh N; Sandler S; Hellerström C
Role of polyamines in mitogenic and secretory responses of pancreatic beta-cells to growth factors.
The American journal of physiology 1990;259(5 Pt 1):C828-33.
1990: Eizirik D L; Welsh M; Strandell E; Welsh N; Sandler S
Interleukin-1 beta depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism.
Endocrinology 1990;127(5):2290-7.
1990: Welsh N
A role for polyamines in glucose-stimulated insulin-gene expression.
The Biochemical journal 1990;271(2):393-7.
1990: Welsh M; Claesson-Welsh L; Hallberg A; Welsh N; Betsholtz C; Arkhammar P; Nilsson T; Heldin C H; Berggren P O
Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5807-11.
1990: Welsh N; Hellerström C
In vitro restoration of insulin production in islets from adult rats treated neonatally with streptozotocin.
Endocrinology 1990;126(4):1842-8.
1990: Oberg C; Welsh N
Nonspecific delivery of substances into pancreatic islet cells by pH-sensitive liposomes in vitro.
Diabète & métabolisme 1990;16(1):48-54.
1990: Welsh N; Oberg C; Hellerström C; Welsh M
Liposome mediated in vitro transfection of pancreatic islet cells.
Biomedica biochimica acta 1990;49(12):1157-64.
1989: Arkhammar P; Nilsson T; Welsh M; Welsh N; Berggren P O
Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells.
The Biochemical journal 1989;264(1):207-15.
1989: Welsh N; Nilsson T; Hallberg A; Arkhammar P; Berggren P O; Sandler S
Human interleukin 1 beta stimulates islet insulin release by a mechanism not dependent on changes in phospholipase C and protein kinase C activities or Ca2+ handling.
Acta endocrinologica 1989;121(5):698-704.
1989: Welsh N; Svensson C; Welsh M
Content of adenine nucleotide translocator mRNA in insulin-producing cells of different functional states.
Diabetes 1989;38(11):1377-80.
1989: Sandler S; Bendtzen K; Eizirik D L; Sjöholm A; Welsh N
Decreased cell replication and polyamine content in insulin-producing cells after exposure to human interleukin 1 beta.
Immunology letters 1989;22(4):267-72.
1989: Rorsman P; Arkhammar P; Bokvist K; Hellerström C; Nilsson T; Welsh M; Welsh N; Berggren P O
Failure of glucose to elicit a normal secretory response in fetal pancreatic beta cells results from glucose insensitivity of the ATP-regulated K+ channels.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4505-9.
1989: Berggren P O; Hallberg A; Welsh N; Arkahammar P; Nilsson T; Welsh M
Transfection of insulin-producing cells with a transforming c-Ha-ras oncogene stimulates phospholipase C activity.
The Biochemical journal 1989;259(3):701-7.
1989: Sandler S; Bendtzen K; Borg L A; Eizirik D L; Strandell E; Welsh N
Studies on the mechanisms causing inhibition of insulin secretion in rat pancreatic islets exposed to human interleukin-1 beta indicate a perturbation in the mitochondrial function.
Endocrinology 1989;124(3):1492-501.
1988: Welsh N; Hallberg A; Sandler S; Hellerström C
Use of liposomes to introduce substances into pancreatic islet cells.
Diabetes 1988;37(8):1123-8.
1988: Welsh N; Sjöholm A
Polyamines and insulin production in isolated mouse pancreatic islets.
The Biochemical journal 1988;252(3):701-7.
1988: Eizirik D L; Sandler S; Welsh N; Hellerström C
Preferential reduction of insulin production in mouse pancreatic islets maintained in culture after streptozotocin exposure.
Endocrinology 1988;122(4):1242-9.
1988: Welsh M; Welsh N; Nilsson T; Arkhammar P; Pepinsky R B; Steiner D F; Berggren P O
Stimulation of pancreatic islet beta-cell replication by oncogenes.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):116-20.
1987: Welsh N; Welsh M; Steiner D F; Hellerström C
Mechanisms of leucine- and theophylline-stimulated insulin biosynthesis in isolated rat pancreatic islets.
The Biochemical journal 1987;246(1):245-8.

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