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David Wemmer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
27
Pelton, Jeffrey
23
Pines, Alexander
13
Lowery, Thomas
11
Kustu, Sydney
10
Rubin, Seth
9
Ruiz, Janette
9
Reid, Brian
9
Cho, Ho
9
Doucleff, Michaeleen
7
Kim, Rosalind
7
Schultz, Peter
7
Yokota, Hisao
6
Yan, Dalai
6
Kim, Sung-Huo
6
Spence, Megan

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Publications

TOP 3
Batchelor Joseph D; Sterling Harry J; Hong Eunmi; Williams Evan R; Wemmer David E
Receiver domains control the active-state stoichiometry of Aquifex aeolicus sigma54 activator NtrC4, as revealed by electrospray ionization mass spectrometry.
Hong Eunmi; Doucleff Michaeleen; Wemmer David E
Structure of the RNA polymerase core-binding domain of sigma(54) reveals a likely conformational fracture point.
Ledbetter M P; Crawford C W; Pines A; Wemmer D E; Knappe S; Kitching J; Budker D
Optical detection of NMR J-spectra at zero magnetic field.

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All Publications

2009: Batchelor Joseph D; Sterling Harry J; Hong Eunmi; Williams Evan R; Wemmer David E
Receiver domains control the active-state stoichiometry of Aquifex aeolicus sigma54 activator NtrC4, as revealed by electrospray ionization mass spectrometry.
Journal of molecular biology 2009;393(3):634-43.
2009: Hong Eunmi; Doucleff Michaeleen; Wemmer David E
Structure of the RNA polymerase core-binding domain of sigma(54) reveals a likely conformational fracture point.
Journal of molecular biology 2009;390(1):70-82.
2009: Ledbetter M P; Crawford C W; Pines A; Wemmer D E; Knappe S; Kitching J; Budker D
Optical detection of NMR J-spectra at zero magnetic field.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2009;199(1):25-9.
2009: Jura Natalia; Endres Nicholas F; Engel Kate; Deindl Sebastian; Das Rahul; Lamers Meindert H; Wemmer David E; Zhang Xuewu; Kuriyan John
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment.
Cell 2009;137(7):1293-307.
2008: Batchelor Joseph D; Doucleff Michaeleen; Lee Chul-Jin; Matsubara Koshi; De Carlo Sacha; Heideker Johanna; Lamers Meindert H; Pelton Jeffrey G; Wemmer David E
Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation.
Journal of molecular biology 2008;384(5):1058-75.
2008: Schröder Leif; Meldrum Tyler; Smith Monica; Lowery Thomas J; Wemmer David E; Pines Alexander
Temperature response of 129Xe depolarization transfer and its application for ultrasensitive NMR detection.
Physical review letters 2008;100(25):257603.
2008: Fawzi Nicolas L; Phillips Aaron H; Ruscio Jory Z; Doucleff Michaeleen; Wemmer David E; Head-Gordon Teresa
Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations.
Journal of the American Chemical Society 2008;130(19):6145-58.
2008: Baxter Nicola J; Blackburn G Michael; Marston James P; Hounslow Andrea M; Cliff Matthew J; Bermel Wolfgang; Williams Nicholas H; Hollfelder Florian; Wemmer David E; Waltho Jonathan P
Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.
Journal of the American Chemical Society 2008;130(12):3952-8.
2008: Schröder Leif; Chavez Lana; Meldrum Tyler; Smith Monica; Lowery Thomas J; Wemmer David E; Pines Alexander
Temperature-controlled molecular depolarization gates in nuclear magnetic resonance.
Angewandte Chemie (International ed. in English) 2008;47(23):4316-20.
2007: Matsuda Shigeo; Fillo Jeremiah D; Henry Allison A; Rai Priyamrada; Wilkens Steven J; Dwyer Tammy J; Geierstanger Bernhard H; Wemmer David E; Schultz Peter G; Spraggon Glen; Romesberg Floyd E
Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.
Journal of the American Chemical Society 2007;129(34):10466-73.
2007: Fraser James S; Merlie John P; Echols Nathaniel; Weisfield Shellie R; Mignot Tâm; Wemmer David E; Zusman David R; Alber Tom
An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.
Molecular microbiology 2007;65(2):319-32.
2007: Doucleff Michaeleen; Pelton Jeffrey G; Lee Peter S; Nixon B Tracy; Wemmer David E
Structural basis of DNA recognition by the alternative sigma-factor, sigma54.
Journal of molecular biology 2007;369(4):1070-8.
2007: Chen Baoyu; Doucleff Michaeleen; Wemmer David E; De Carlo Sacha; Huang Hector H; Nogales Eva; Hoover Timothy R; Kondrashkina Elena; Guo Liang; Nixon B Tracy
ATP ground- and transition states of bacterial enhancer binding AAA+ ATPases support complex formation with their target protein, sigma54.
Structure (London, England : 1993) 2007;15(4):429-40.
2007: Lowery Thomas J; Pelton Jeffrey G; Chandonia John-Marc; Kim Rosalind; Yokota Hisao; Wemmer David E
NMR structure of the N-terminal domain of the replication initiator protein DnaA.
Journal of structural and functional genomics 2007;8(1):11-7.
2007: Tang Yinjie J; Hwang Judy S; Wemmer David E; Keasling Jay D
Shewanella oneidensis MR-1 fluxome under various oxygen conditions.
Applied and environmental microbiology 2007;73(3):718-29.
2007: Garcia Sandra; Chavez Lana; Lowery Thomas J; Han Song-I; Wemmer David E; Pines Alexander
Sensitivity enhancement by exchange mediated magnetization transfer of the xenon biosensor signal.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2007;184(1):72-7.
2006: Simon Matthew D; Feldman Morris E; Rauh Daniel; Maris Ann E; Wemmer David E; Shokat Kevan M
Structure and properties of a re-engineered homeodomain protein-DNA interface.
ACS chemical biology 2006;1(12):755-60.
2006: Schröder Leif; Lowery Thomas J; Hilty Christian; Wemmer David E; Pines Alexander
Molecular imaging using a targeted magnetic resonance hyperpolarized biosensor.
Science (New York, N.Y.) 2006;314(5798):446-9.
2006: Pirruccello Michelle; Sondermann Holger; Pelton Jeffrey G; Pellicena Patricia; Hoelz André; Chernoff Jonathan; Wemmer David E; Kuriyan John
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.
Journal of molecular biology 2006;361(2):312-26.
2006: Roberts Anne; Pelton Jeffrey G; Wemmer David E
Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase.
Magnetic resonance in chemistry : MRC 2006;44 Spec No():S71-82.
2006: Mynar Justin L; Lowery Thomas J; Wemmer David E; Pines Alexander; Fréchet Jean M J
Xenon biosensor amplification via dendrimer-cage supramolecular constructs.
Journal of the American Chemical Society 2006;128(19):6334-5.
2006: Lim Kwang Hun; Nguyen Tuan N; Damo Steven M; Mazur Tanya; Ball Haydn L; Prusiner Stanley B; Pines Alexander; Wemmer David E
Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L).
Solid state nuclear magnetic resonance 2006;29(1-3):183-90.
2006: Lowery Thomas J; Garcia Sandra; Chavez Lana; Ruiz E Janette; Wu Tom; Brotin Thierry; Dutasta Jean-Pierre; King David S; Schultz Peter G; Pines Alex; Wemmer David E
Optimization of xenon biosensors for detection of protein interactions.
Chembiochem : a European journal of chemical biology 2006;7(1):65-73.
2005: Wemmer David E; Kern Dorothee
Beryllofluoride binding mimics phosphorylation of aspartate in response regulators.
Journal of bacteriology 2005;187(24):8229-30.
2005: Wemmer David E; Kern Dorothee
Rebuttal: conformational changes of Spo0F along the phosphotransfer pathway.
Journal of bacteriology 2005;187(24):8228.
2005: Hilty Christian; Lowery Thomas J; Wemmer David E; Pines Alexander
Spectrally resolved magnetic resonance imaging of a xenon biosensor.
Angewandte Chemie (International ed. in English) 2005;45(1):70-3.
2005: Doucleff Michaeleen; Malak Lawrence T; Pelton Jeffrey G; Wemmer David E
The C-terminal RpoN domain of sigma54 forms an unpredicted helix-turn-helix motif similar to domains of sigma70.
The Journal of biological chemistry 2005;280(50):41530-6.
2005: Pelton Jeffrey G; Shi Jianxia; Yokota Hisao; Kim Rosalind; Wemmer David E
NMR structure of hypothetical protein MG354 from Mycoplasma genitalium.
Proteins 2005;61(3):666-8.
2005: Nixon B Tracy; Yennawar Hemant P; Doucleff Michaeleen; Pelton Jeffrey G; Wemmer David E; Krueger Susan; Kondrashkina Elena
SAS solution structures of the apo and Mg2+/BeF3(-)-bound receiver domain of DctD from Sinorhizobium meliloti.
Biochemistry 2005;44(42):13962-9.
2005: Doucleff Michaeleen; Chen Baoyu; Maris Ann E; Wemmer David E; Kondrashkina Elena; Nixon B Tracy
Negative regulation of AAA + ATPase assembly by two component receiver domains: a transcription activation mechanism that is conserved in mesophilic and extremely hyperthermophilic bacteria.
Journal of molecular biology 2005;353(2):242-55.
2005: Kim Hui Sun; Damo Steven M; Lee Seok-Yong; Wemmer David; Klinman Judith P
Structure and hydride transfer mechanism of a moderate thermophilic dihydrofolate reductase from Bacillus stearothermophilus and comparison to its mesophilic and hyperthermophilic homologues.
Biochemistry 2005;44(34):11428-39.
2005: Choi Yun-Jeong; Ryu Kyoung-Seok; Ko Yun-Mi; Chae Young-Kee; Pelton Jeffrey G; Wemmer David E; Choi Byong-Seok
Biophysical characterization of the interaction domains and mapping of the contact residues in the XPF-ERCC1 complex.
The Journal of biological chemistry 2005;280(31):28644-52.
2005: Han Song-I; Garcia Sandra; Lowery Thomas J; Ruiz E Janette; Seeley Juliette A; Chavez Lana; King David S; Wemmer David E; Pines Alexander
NMR-based biosensing with optimized delivery of polarized 129Xe to solutions.
Analytical chemistry 2005;77(13):4008-12.
2005: Lowery Thomas J; Doucleff Michaeleen; Ruiz E Janette; Rubin Seth M; Pines Alexander; Wemmer David E
Distinguishing multiple chemotaxis Y protein conformations with laser-polarized 129Xe NMR.
Protein science : a publication of the Protein Society 2005;14(4):848-55.
2005: Roberts Anne; Lee Seok-Yong; McCullagh Emma; Silversmith Ruth E; Wemmer David E
YbiV from Escherichia coli K12 is a HAD phosphatase.
Proteins 2005;58(4):790-801.
2005: Rai Priyamvada; Wemmer David E; Linn Stuart
Preferential binding and structural distortion by Fe2+ at RGGG-containing DNA sequences correlates with enhanced oxidative cleavage at such sequences.
Nucleic acids research 2005;33(2):497-510.
2004: Spence Megan M; Ruiz E Janette; Rubin Seth M; Lowery Thomas J; Winssinger Nicolas; Schultz Peter G; Wemmer David E; Pines Alexander
Development of a functionalized xenon biosensor.
Journal of the American Chemical Society 2004;126(46):15287-94.
2004: Lowery Thomas J; Rubin Seth M; Ruiz E Janette; Pines Alexander; Wemmer David E
Design of a conformation-sensitive xenon-binding cavity in the ribose-binding protein.
Angewandte Chemie (International ed. in English) 2004;43(46):6320-2.
2004: Zhang Qing; Dwyer Tammy J; Tsui Vickie; Case David A; Cho Junhyeong; Dervan Peter B; Wemmer David E
NMR structure of a cyclic polyamide-DNA complex.
Journal of the American Chemical Society 2004;126(25):7958-66.
2004: Shi Jianxia; Pelton Jeffrey G; Cho Ho S; Wemmer David E
Protein signal assignments using specific labeling and cell-free synthesis.
Journal of biomolecular NMR 2004;28(3):235-47.
2003: Lowery Thomas J; Rubin Seth M; Ruiz E Janette; Spence Megan M; Winssinger Nicolas; Schultz Peter G; Pines Alexander; Wemmer David E
Applications of laser-polarized 129Xe to biomolecular assays.
Magnetic resonance imaging 2003;21(10):1235-9.
2003: Wemmer David E
The energetics of structural change in maltose-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12529-30.
2003: Lee Seok-Yong; De La Torre Armando; Yan Dalai; Kustu Sydney; Nixon B Tracy; Wemmer David E
Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains.
Genes & development 2003;17(20):2552-63.
2003: Nguyen Tuan N; Wemmer David E
Complete resonance assignments for the nudix hydrolase DR2356 of Deinococcus radiodurans.
Journal of biomolecular NMR 2003;27(2):181-2.
2003: Hastings Curtis A; Lee Seok-Yong; Cho Ho S; Yan Dalai; Kustu Sydney; Wemmer David E
High-resolution solution structure of the beryllofluoride-activated NtrC receiver domain.
Biochemistry 2003;42(30):9081-90.
2003: Gardino Alexandra K; Volkman Brian F; Cho Ho S; Lee Seok-Yong; Wemmer David E; Kern Dorothee
The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system.
Journal of molecular biology 2003;331(1):245-54.
2003: Shin Dong Hae; Roberts Anne; Jancarik Jaru; Yokota Hisao; Kim Rosalind; Wemmer David E; Kim Sung-Hou
Crystal structure of a phosphatase with a unique substrate binding domain from Thermotoga maritima.
Protein science : a publication of the Protein Society 2003;12(7):1464-72.
2003: Rubin Seth M; Pelton Jeffrey G; Yokota Hisao; Kim Rosalind; Wemmer David E
Solution structure of a putative ribosome binding protein from Mycoplasma pneumoniae and comparison to a distant homolog.
Journal of structural and functional genomics 2003;4(4):235-43.
2002: Hawkins Cheryl A; Baird Eldon E; Dervan Peter B; Wemmer David E
Analysis of hairpin polyamide complexes having DNA binding sites in close proximity.
Journal of the American Chemical Society 2002;124(43):12689-96.
2002: Rubin Seth M; Lee Seok-Yong; Ruiz E Janette; Pines Alexander; Wemmer David E
Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy.
Journal of molecular biology 2002;322(2):425-40.
2002: Lim Kwang Hun; Nguyen Tuan; Mazur Tanya; Wemmer David E; Pines Alexander
Sensitivity enhancement in multiple-quantum NMR experiments with CPMG detection.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;157(1):160-2.
2002: Supekova Lubica; Pezacki John Paul; Su Andrew I; Loweth Colin J; Riedl Rainer; Geierstanger Bernhard; Schultz Peter G; Wemmer David E
Genomic effects of polyamide/DNA interactions on mRNA expression.
Chemistry & biology 2002;9(7):821-7.
2002: Liu Kai; Kelly Jeffery W; Wemmer David E
Native state hydrogen exchange study of suppressor and pathogenic variants of transthyretin.
Journal of molecular biology 2002;320(4):821-32.
2002: Wang Weiru; Cho Ho S; Kim Rosalind; Jancarik Jaru; Yokota Hisao; Nguyen Henry H; Grigoriev Igor V; Wemmer David E; Kim Sung-Hou
Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
Journal of molecular biology 2002;319(2):421-31.
2002: Westler William M; Frey Perry A; Lin Jing; Wemmer David E; Morimoto Hiromi; Williams Phillip G; Markley John L
Evidence for a strong hydrogen bond in the catalytic dyad of transition-state analogue inhibitor complexes of chymotrypsin from proton-triton NMR isotope shifts.
Journal of the American Chemical Society 2002;124(16):4196-7.
2001: Cho H S; Pelton J G; Yan D; Kustu S; Wemmer D E
Phosphoaspartates in bacterial signal transduction.
Current opinion in structural biology 2001;11(6):679-84.
2001: Havlin R H; Laws D D; Bitter H M; Sanders L K; Sun H; Grimley J S; Wemmer D E; Pines A; Oldfield E
An experimental and theoretical investigation of the chemical shielding tensors of (13)C(alpha) of alanine, valine, and leucine residues in solid peptides and in proteins in solution.
Journal of the American Chemical Society 2001;123(42):10362-9.
2001: Rai P; Cole T D; Wemmer D E; Linn S
Localization of Fe(2+) at an RTGR sequence within a DNA duplex explains preferential cleavage by Fe(2+) and H2O2.
Journal of molecular biology 2001;312(5):1089-101.
2001: Laws D D; Bitter H M; Liu K; Ball H L; Kaneko K; Wille H; Cohen F E; Prusiner S B; Pines A; Wemmer D E
Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11686-90.
2001: Spence M M; Rubin S M; Dimitrov I E; Ruiz E J; Wemmer D E; Pines A; Yao S Q; Tian F; Schultz P G
Functionalized xenon as a biosensor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10654-7.
2001: Rubin S M; Spence M M; Pines A; Wemmer D E
Characterization of the effects of nonspecific xenon-protein interactions on (129)Xe chemical shifts in aqueous solution: further development of xenon as a biomolecular probe.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2001;152(1):79-86.
2001: Rubin S M; Spence M M; Dimitrov I E; Ruiz E J; Pines A; Wemmer D E
Detection of a conformational change in maltose binding protein by (129)Xe NMR spectroscopy.
Journal of the American Chemical Society 2001;123(35):8616-7.
2001: Cho H; Wang W; Kim R; Yokota H; Damo S; Kim S H; Wemmer D; Kustu S; Yan D
BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8525-30.
2001: Zhang Q; Harada K; Cho H S; Frankel A D; Wemmer D E
Structural characterization of the complex of the Rev response element RNA with a selected peptide.
Chemistry & biology 2001;8(5):511-20.
2001: Lee S Y; Cho H S; Pelton J G; Yan D; Berry E A; Wemmer D E
Crystal structure of activated CheY. Comparison with other activated receiver domains.
The Journal of biological chemistry 2001;276(19):16425-31.
2001: Volkman B F; Lipson D; Wemmer D E; Kern D
Two-state allosteric behavior in a single-domain signaling protein.
Science (New York, N.Y.) 2001;291(5512):2429-33.
2001: Bastos M; Pease J H; Wemmer D E; Murphy K P; Connelly P R
Thermodynamics of the helix-coil transition: Binding of S15 and a hybrid sequence, disulfide stabilized peptide to the S-protein.
Proteins 2001;42(4):523-30.
2001: Cave J W; Cho H S; Batchelder A M; Yokota H; Kim R; Wemmer D E
Solution nuclear magnetic resonance structure of a protein disulfide oxidoreductase from Methanococcus jannaschii.
Protein science : a publication of the Protein Society 2001;10(2):384-96.
2001: Hawkins C A; Watson C; Yan Y; Gong B; Wemmer D E
Structural analysis of the binding modes of minor groove ligands comprised of disubstituted benzenes.
Nucleic acids research 2001;29(4):936-42.
2001: Lee S Y; Cho H S; Pelton J G; Yan D; Henderson R K; King D S; Huang L; Kustu S; Berry E A; Wemmer D E
Crystal structure of an activated response regulator bound to its target.
Nature structural biology 2001;8(1):52-6.
2000: Cave J W; Kremer W; Wemmer D E
Backbone dynamics of sequence specific recognition and binding by the yeast Pho4 bHLH domain probed by NMR.
Protein science : a publication of the Protein Society 2000;9(12):2354-65.
2000: Rogers J P; Luginbühl P; Pemberton K; Harty P; Wemmer D E; Stevens R C
Structure-activity relationships in a peptidic alpha7 nicotinic acetylcholine receptor antagonist.
Journal of molecular biology 2000;304(5):911-26.
2000: Liu K; Cho H S; Hoyt D W; Nguyen T N; Olds P; Kelly J W; Wemmer D E
Deuterium-proton exchange on the native wild-type transthyretin tetramer identifies the stable core of the individual subunits and indicates mobility at the subunit interface.
Journal of molecular biology 2000;303(4):555-65.
2000: Liu K; Cho H S; Lashuel H A; Kelly J W; Wemmer D E
A glimpse of a possible amyloidogenic intermediate of transthyretin.
Nature structural biology 2000;7(9):754-7.
2000: Rubin S M; Spence M M; Goodson B M; Wemmer D E; Pines A
Evidence of nonspecific surface interactions between laser-polarized xenon and myoglobin in solution.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9472-5.
2000: Cho H S; Lee S Y; Yan D; Pan X; Parkinson J S; Kustu S; Wemmer D E; Pelton J G
NMR structure of activated CheY.
Journal of molecular biology 2000;297(3):543-51.
2000: Keating K A; Myers J D; Pelton J G; Bair R A; Wemmer D E; Ellis P D
Development and use of a virtual NMR facility.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;143(1):172-83.
2000: Robertson S A; Harada K; Frankel A D; Wemmer D E
Structure determination and binding kinetics of a DNA aptamer-argininamide complex.
Biochemistry 2000;39(5):946-54.
2000: Wemmer D E
Designed sequence-specific minor groove ligands.
Annual review of biophysics and biomolecular structure 2000;29():439-61.
1999: Kern D; Volkman B F; Luginbühl P; Nohaile M J; Kustu S; Wemmer D E
Structure of a transiently phosphorylated switch in bacterial signal transduction.
Nature 1999;402(6764):894-8.
1999: Yan D; Cho H S; Hastings C A; Igo M M; Lee S Y; Pelton J G; Stewart V; Wemmer D E; Kustu S
Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14789-94.
1999: Pelton J G; Kustu S; Wemmer D E
Solution structure of the DNA-binding domain of NtrC with three alanine substitutions.
Journal of molecular biology 1999;292(5):1095-110.
1999: Cho C Y; Liu C W; Wemmer D E; Schultz P G
Cyclic and linear oligocarbamate ligands for human thrombin.
Bioorganic & medicinal chemistry 1999;7(6):1171-9.
1999: Rogers J P; Luginbühl P; Shen G S; McCabe R T; Stevens R C; Wemmer D E
NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors.
Biochemistry 1999;38(13):3874-82.
1999: Peteranderl R; Rabenstein M; Shin Y K; Liu C W; Wemmer D E; King D S; Nelson H C
Biochemical and biophysical characterization of the trimerization domain from the heat shock transcription factor.
Biochemistry 1999;38(12):3559-69.
1999: Wemmer D E
Ligands recognizing the minor groove of DNA: development and applications.
Biopolymers 1999;52(4):197-211.
1999: Wemmer D
Solid-state nuclear magnetic resonance of protein deposits.
Methods in enzymology 1999;309():536-59.
1998: Wemmer D E
The rational design of sequence-specific DNA minor groove binders using a 2:1 motif.
Current opinion in drug discovery & development 1998;1(2):200-7.
1998: Wemmer D
Reading DNA.
Nature structural biology 1998;5(3):169-71.
1998: Gehring K; Zhang X; Hall J; Nikaido H; Wemmer D E
An NMR study of ligand binding by maltodextrin binding protein.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1998;76(2-3):189-97.
1997: Lee A L; Volkman B F; Robertson S A; Rudner D Z; Barbash D A; Cline T W; Kanaar R; Rio D C; Wemmer D E
Chemical shift mapping of the RNA-binding interface of the multiple-RBD protein sex-lethal.
Biochemistry 1997;36(47):14306-17.
1997: Nohaile M; Kern D; Wemmer D; Stedman K; Kustu S
Structural and functional analyses of activating amino acid substitutions in the receiver domain of NtrC: evidence for an activating surface.
Journal of molecular biology 1997;273(1):299-316.
1997: Wemmer D E; Dervan P B
Targeting the minor groove of DNA.
Current opinion in structural biology 1997;7(3):355-61.
1997: Volkman B F; Wemmer D E
Deletion of a single amino acid changes the folding of an apamin hybrid sequence peptide to that of endothelin.
Biopolymers 1997;41(4):451-60.
1996: Heller J; Kolbert A C; Larsen R; Ernst M; Bekker T; Baldwin M; Prusiner S B; Pines A; Wemmer D E
Solid-state NMR studies of the prion protein H1 fragment.
Protein science : a publication of the Protein Society 1996;5(8):1655-61.
1996: Kubinec M G; Culf A S; Cho H; Lee D C; Burkham J; Morimoto H; Williams P G; Wemmer D E
Applications of tritium NMR to macromolecules: a study of two nucleic acid molecules.
Journal of biomolecular NMR 1996;7(3):236-46.
1996: Fagan P A; Fàbrega C; Eritja R; Goodman M F; Wemmer D E
NMR study of the conformation of the 2-aminopurine:cytosine mismatch in DNA.
Biochemistry 1996;35(13):4026-33.
1996: Fagan P A; Spielmann H P; Sigurdsson S; Rink S M; Hopkins P B; Wemmer D E
An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugate.
Nucleic acids research 1996;24(8):1566-73.
1996: Geierstanger B H; Mrksich M; Dervan P B; Wemmer D E
Extending the recognition site of designed minor groove binding molecules.
Nature structural biology 1996;3(4):321-4.
1996: Cho H S; Liu C W; Damberger F F; Pelton J G; Nelson H C; Wemmer D E
Yeast heat shock transcription factor N-terminal activation domains are unstructured as probed by heteronuclear NMR spectroscopy.
Protein science : a publication of the Protein Society 1996;5(2):262-9.
1996: Wemmer D E
New features in RNA recognition: a Tat-TAR complex.
Chemistry & biology 1996;3(1):17-9.
1995: Liu H; Spielmann H P; Ulyanov N B; Wemmer D E; James T L
Interproton distance bounds from 2D NOE intensities: effect of experimental noise and peak integration errors.
Journal of biomolecular NMR 1995;6(4):390-402.
1995: Damberger F F; Pelton J G; Liu C; Cho H; Harrison C J; Nelson H C; Wemmer D E
Refined solution structure and dynamics of the DNA-binding domain of the heat shock factor from Kluyveromyces lactis.
Journal of molecular biology 1995;254(4):704-19.
1995: Spielmann H P; Dwyer T J; Hearst J E; Wemmer D E
Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics.
Biochemistry 1995;34(40):12937-53.
1995: Kanaar R; Lee A L; Rudner D Z; Wemmer D E; Rio D C
Interaction of the sex-lethal RNA binding domains with RNA.
The EMBO journal 1995;14(18):4530-9.
1995: Spielmann H P; Wemmer D E; Jacobsen J P
Solution structure of a DNA complex with the fluorescent bis-intercalator TOTO determined by NMR spectroscopy.
Biochemistry 1995;34(27):8542-53.
1995: Spielmann H P; Fagan P A; Bregant T M; Little R D; Wemmer D E
The binding modes of a rationally designed photoactivated DNA nuclease determined by NMR.
Nucleic acids research 1995;23(9):1576-83.
1995: Rentzeperis D; Marky L A; Dwyer T J; Geierstanger B H; Pelton J G; Wemmer D E
Interaction of minor groove ligands to an AAATT/AATTT site: correlation of thermodynamic characterization and solution structure.
Biochemistry 1995;34(9):2937-45.
1995: Spielmann H P; Dwyer T J; Sastry S S; Hearst J E; Wemmer D E
DNA structural reorganization upon conversion of a psoralen furan-side monoadduct to an interstrand cross-link: implications for DNA repair.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2345-9.
1995: Jacobsen J P; Pedersen J B; Hansen L F; Wemmer D E
Site selective bis-intercalation of a homodimeric thiazole orange dye in DNA oligonucleotides.
Nucleic acids research 1995;23(5):753-60.
1995: Volkman B F; Nohaile M J; Amy N K; Kustu S; Wemmer D E
Three-dimensional solution structure of the N-terminal receiver domain of NTRC.
Biochemistry 1995;34(4):1413-24.
1995: Geierstanger B H; Wemmer D E
Complexes of the minor groove of DNA.
Annual review of biophysics and biomolecular structure 1995;24():463-93.
1995: Pelton J G; Wemmer D E
Heteronuclear NMR pulse sequences applied to biomolecules.
Annual review of physical chemistry 1995;46():139-67.
1994: Lee A L; Kanaar R; Rio D C; Wemmer D E
Resonance assignments and solution structure of the second RNA-binding domain of sex-lethal determined by multidimensional heteronuclear magnetic resonance.
Biochemistry 1994;33(46):13775-86.
1994: Geierstanger B H; Mrksich M; Dervan P B; Wemmer D E
Design of a G.C-specific DNA minor groove-binding peptide.
Science (New York, N.Y.) 1994;266(5185):646-50.
1994: Damberger F F; Pelton J G; Harrison C J; Nelson H C; Wemmer D E
Solution structure of the DNA-binding domain of the heat shock transcription factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Protein science : a publication of the Protein Society 1994;3(10):1806-21.
1994: Acedo M; Fàbrega C; Aviño A; Goodman M; Fagan P; Wemmer D; Eritja R
A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides.
Nucleic acids research 1994;22(15):2982-9.
1994: Singh S B; Wemmer D E; Kollman P A
Relative binding affinities of distamycin and its analog to d(CGCAAGTTGGC).d(GCCAACTTGCG): comparison of simulation results with experiment.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(16):7673-7.
1994: Geierstanger B H; Volkman B F; Kremer W; Wemmer D E
Short peptide fragments derived from HMG-I/Y proteins bind specifically to the minor groove of DNA.
Biochemistry 1994;33(17):5347-55.
1994: Geierstanger B H; Jacobsen J P; Mrksich M; Dervan P B; Wemmer D E
Structural and dynamic characterization of the heterodimeric and homodimeric complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin bound to the minor groove of DNA.
Biochemistry 1994;33(10):3055-62.
1994: Pagel M D; Wemmer D E
Solution structure of a core peptide derived from scyllatoxin.
Proteins 1994;18(3):205-15.
1994: Zhou H X; Lyu P; Wemmer D E; Kallenbach N R
Alpha helix capping in synthetic model peptides by reciprocal side chain-main chain interactions: evidence for an N terminal "capping box".
Proteins 1994;18(1):1-7.
1994: Wemmer D E; Williams P G
Use of nuclear magnetic resonance in probing ligand-macromolecule interactions.
Methods in enzymology 1994;239():739-67.
1993: Highsmith S; Kubinec M; Jaiswal D K; Morimoto H; Williams P G; Wemmer D E
[2-3H]ATP synthesis and 3H NMR spectroscopy of enzyme-nucleotide complexes: ADP and ADP.Vi bound to myosin subfragment 1.
Journal of biomolecular NMR 1993;3(3):325-34.
1993: Lyu P C; Wemmer D E; Zhou H X; Pinker R J; Kallenbach N R
Capping interactions in isolated alpha helices: position-dependent substitution effects and structure of a serine-capped peptide helix.
Biochemistry 1993;32(2):421-5.
1993: Wemmer D E; Wedemayer G J; Glazer A N
Phycobilins of cryptophycean algae. Novel linkage of dihydrobiliverdin in a phycoerythrin 555 and a phycocyanin 645.
The Journal of biological chemistry 1993;268(3):1658-69.
1992: Storrs R W; Truckses D; Wemmer D E
Helix propagation in trifluoroethanol solutions.
Biopolymers 1992;32(12):1695-702.
1992: Tomic M T; Somoza J R; Wemmer D E; Park Y W; Cho J M; Kim S H
1H resonance assignments, secondary structure and general topology of single-chain monellin in solution as determined by 1H 2D-NMR.
Journal of biomolecular NMR 1992;2(6):557-72.
1992: Mrksich M; Wade W S; Dwyer T J; Geierstanger B H; Wemmer D E; Dervan P B
Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7586-90.
1992: Amaratunga M; Snowden-Ifft E; Wemmer D E; Benight A S
Studies of DNA dumbbells. II. Construction and characterization of DNA dumbbells with a 16 base-pair duplex stem and Tn end loops (n = 2, 3, 4, 6, 8, 10, 14).
Biopolymers 1992;32(7):865-79.
1992: Rye H S; Yue S; Wemmer D E; Quesada M A; Haugland R P; Mathies R A; Glazer A N
Stable fluorescent complexes of double-stranded DNA with bis-intercalating asymmetric cyanine dyes: properties and applications.
Nucleic acids research 1992;20(11):2803-12.
1992: Gaillard J; Albrand J P; Moulis J M; Wemmer D E
Sequence-specific assignments of the 1H nuclear magnetic resonance spectra of reduced high-potential ferredoxin (HiPIP) from Chromatium vinosum.
Biochemistry 1992;31(24):5632-9.
1992: Werner M H; Wemmer D E
Identification of a protein-binding surface by differential amide hydrogen-exchange measurements. Application to Bowman-Birk serine-protease inhibitor.
Journal of molecular biology 1992;225(3):873-89.
1992: Sastry S S; Spielmann H P; Dwyer T J; Wemmer D E; Hearst J E
Recent advances in the synthesis and structure determination of site specifically psoralen-modified DNA oligonucleotides.
Journal of photochemistry and photobiology. B, Biology 1992;14(1-2):65-79.
1992: Wedemayer G J; Kidd D G; Wemmer D E; Glazer A N
Phycobilins of cryptophycean algae. Occurrence of dihydrobiliverdin and mesobiliverdin in cryptomonad biliproteins.
The Journal of biological chemistry 1992;267(11):7315-31.
1992: Werner M H; Wemmer D E
Three-dimensional structure of soybean trypsin/chymotrypsin Bowman-Birk inhibitor in solution.
Biochemistry 1992;31(4):999-1010.
1991: Kallick D A; Wemmer D E
1H NMR of 5'CGCGTATATACGCG3', a duplex and a four-membered loop.
Nucleic acids research 1991;19(21):6041-6.
1991: Gehring K; Williams P G; Pelton J G; Morimoto H; Wemmer D E
Tritium NMR spectroscopy of ligand binding to maltose-binding protein.
Biochemistry 1991;30(22):5524-31.
1991: McIntire W S; Wemmer D E; Chistoserdov A; Lidstrom M E
A new cofactor in a prokaryotic enzyme: tryptophan tryptophylquinone as the redox prosthetic group in methylamine dehydrogenase.
Science (New York, N.Y.) 1991;252(5007):817-24.
1991: Werner M H; Wemmer D E
1H assignments and secondary structure determination of the soybean trypsin/chymotrypsin Bowman-Birk inhibitor.
Biochemistry 1991;30(14):3356-64.
1991: Wedemayer G J; Wemmer D E; Glazer A N
Phycobilins of cryptophycean algae. Structures of novel bilins with acryloyl substituents from phycoerythrin 566.
The Journal of biological chemistry 1991;266(8):4731-41.
1990: Pease A C; Wemmer D E
Characterization of the secondary structure and melting of a self-cleaved RNA hammerhead domain by 1H NMR spectroscopy.
Biochemistry 1990;29(38):9039-46.
1990: Pease J H; Storrs R W; Wemmer D E
Folding and activity of hybrid sequence, disulfide-stabilized peptides.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5643-7.
1990: Pelton J G; Wemmer D E
Structure and dynamics of distamycin A with d(CGCAAATTGGC):d(GCCAATTTGCG) at low drug:DNA ratios.
Journal of biomolecular structure & dynamics 1990;8(1):81-97.
1990: Snowden-Ifft E A; Wemmer D E
Characterization of the structure and melting of DNAs containing backbone nicks and gaps.
Biochemistry 1990;29(25):6017-25.
1990: Janes S M; Mu D; Wemmer D; Smith A J; Kaur S; Maltby D; Burlingame A L; Klinman J P
A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase.
Science (New York, N.Y.) 1990;248(4958):981-7.
1989: Pelton J G; Wemmer D E
Structural characterization of a 2:1 distamycin A.d(CGCAAATTGGC) complex by two-dimensional NMR.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(15):5723-7.
1989: Pease J H; Kumar N V; Schweitz H; Kallenbach N R; Wemmer D E
NMR studies of toxin III from the sea anemone Radianthus paumotensis and comparison of its secondary structure with related toxins.
Biochemistry 1989;28(5):2199-204.
1989: Kintanar A; Huang W C; Schindele D C; Wemmer D E; Drobny G
Dynamics of bases in hydrated [d(CGCGAATTCGCG)]2.
Biochemistry 1989;28(1):282-93.
1988: Pease J H; Wemmer D E
Solution structure of apamin determined by nuclear magnetic resonance and distance geometry.
Biochemistry 1988;27(22):8491-8.
1988: Pelton J G; Wemmer D E
Structural modeling of the distamycin A-d(CGCGAATTCGCG)2 complex using 2D NMR and molecular mechanics.
Biochemistry 1988;27(21):8088-96.
1988: Kleanthous C; Wemmer D E; Schachman H K
The role of an active site histidine in the catalytic mechanism of aspartate transcarbamoylase.
The Journal of biological chemistry 1988;263(26):13062-7.
1988: Kumar N V; Wemmer D E; Kallenbach N R
Structure of P401 (mast cell degranulating peptide) in solution.
Biophysical chemistry 1988;31(1-2):113-9.
1988: Kim S H; Tomic M T; Wemmer D E; Pearlman D; Holbrook S
Structure of DNA damaged by UV and psoralen.
Biochemical pharmacology 1988;37(9):1791.
1988: Benight A S; Schurr J M; Flynn P F; Reid B R; Wemmer D E
Melting of a self-complementary DNA minicircle. Comparison of optical melting theory with exchange broadening of the nuclear magnetic resonance spectrum.
Journal of molecular biology 1988;200(2):377-99.
1987: Tomic M T; Wemmer D E; Kim S H
Structure of a psoralen cross-linked DNA in solution by nuclear magnetic resonance.
Science (New York, N.Y.) 1987;238(4834):1722-5.
1987: Srivenugopal K S; Wemmer D E; Morris D R
Aggregation of DNA by analogs of spermidine; enzymatic and structural studies.
Nucleic acids research 1987;15(6):2563-80.
1986: Wemmer D E; Kumar N V; Metrione R M; Lazdunski M; Drobny G; Kallenbach N R
NMR analysis and sequence of toxin II from the sea anemone Radianthus paumotensis.
Biochemistry 1986;25(22):6842-9.
1986: Klevit R E; Wemmer D E; Reid B R
1H NMR studies on the interaction between distamycin A and a symmetrical DNA dodecamer.
Biochemistry 1986;25(11):3296-303.
1985: Wemmer D E; Benight A S
Preparation and melting of single strand circular DNA loops.
Nucleic acids research 1985;13(23):8611-21.
1985: Klevit R E; Blumenthal D K; Wemmer D E; Krebs E G
Interaction of calmodulin and a calmodulin-binding peptide from myosin light chain kinase: major spectral changes in both occur as the result of complex formation.
Biochemistry 1985;24(27):8152-7.
1985: Wemmer D E; Wand A J; Seeman N C; Kallenbach N R
NMR analysis of DNA junctions: imino proton NMR studies of individual arms and intact junction.
Biochemistry 1985;24(21):5745-9.
1985: Wemmer D E; Srivenugopal K S; Reid B R; Morris D R
Nuclear magnetic resonance studies of polyamine binding to a defined DNA sequence.
Journal of molecular biology 1985;185(2):457-9.
1985: Weber P L; Wemmer D E; Reid B R
1H NMR studies of lambda cro repressor. 2. Sequential resonance assignments of the 1H NMR spectrum.
Biochemistry 1985;24(17):4553-62.
1985: Hare D R; Ribeiro N S; Wemmer D E; Reid B R
Complete assignment of the imino protons of Escherichia coli valine transfer RNA: two-dimensional NMR studies in water.
Biochemistry 1985;24(16):4300-6.
1985: Langowski J; Fujimoto B S; Wemmer D E; Benight A S; Drobny G; Shibata J H; Schurr J M
Deformational dynamics and NMR relaxation of supercoiled DNAs.
Biopolymers 1985;24(6):1023-56.
1985: Wemmer D E; Chou S H; Hare D R; Reid B R
Duplex-hairpin transitions in DNA: NMR studies on CGCGTATACGCG.
Nucleic acids research 1985;13(10):3755-72.
1984: Wemmer D E; Chou S H; Reid B R
Sequence-specific recognition of DNA. Nuclear magnetic resonance assignments and structural comparison of wild-type and mutant lambda OR3 operator DNA.
Journal of molecular biology 1984;180(1):41-60.
1984: Roberts J K; Callis J; Wemmer D; Walbot V; Jardetzky O
Mechanisms of cytoplasmic pH regulation in hypoxic maize root tips and its role in survival under hypoxia.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(11):3379-83.
1984: Wemmer D E; Chou S H; Hare D R; Reid B R
Sequence-specific recognition of DNA: assignment of nonexchangeable proton resonances in the consensus Pribnow promoter DNA sequence by two-dimensional NMR.
Biochemistry 1984;23(10):2262-8.
1984: Chou S H; Wemmer D E; Hare D R; Reid B R
Sequence-specific recognition of DNA: NMR studies of the imino protons of a synthetic RNA polymerase promoter.
Biochemistry 1984;23(10):2257-62.
1983: Hare D R; Wemmer D E; Chou S H; Drobny G; Reid B R
Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods.
Journal of molecular biology 1983;171(3):319-36.
1983: Chou S H; Hare D R; Wemmer D E; Reid B R
Sequence-specific recognition of deoxyribonucleic acid. Chemical synthesis and nuclear magnetic resonance assignment of the imino protons of lambda OR3 operator deoxyribonucleic acid.
Biochemistry 1983;22(13):3037-41.
1981: Wemmer D; Shvo H; Ribeiro A A; Bray R P; Jardetzky O
High-resolution proton nuclear magnetic resonance studies of the exchangeable resonances of the lac repressor headpiece.
Biochemistry 1981;20(12):3351-4.
1981: Ribeiro A A; Wemmer D; Bray R P; Jardetzky O
A folded structure for the lac-repressor headpiece.
Biochemical and biophysical research communications 1981;99(2):668-74.
1981: Wemmer D; Ribeiro A A; Bray R P; Wade-Jardetzky N G; Jardetzky O
High-resolution nuclear magnetic resonance studies of the Lac repressor. 3. Unfolding of the Lac repressor headpiece.
Biochemistry 1981;20(4):829-33.
1981: Ribeiro A A; Wemmer D; Bray R P; Wade-Jardetzky N G; Jardetzky O
High-resolution nuclear magnetic resonance studies of the Lac repressor. 2. Partial analysis of the aliphatic region of the Lac repressor headpiece spectrum.
Biochemistry 1981;20(4):823-9.
1981: Ribeiro A A; Wemmer D; Bray R P; Wade-Jardetzky N G; Jardetzky O
High-resolution nuclear magnetic resonance studies of the Lac repressor. 1. Assignments of tyrosine resonances in the N-terminal headpiece.
Biochemistry 1981;20(4):818-23.

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