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Wei Wen

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Tao Liu; Simone Reppermund; Perminder S Sachdev; Julian N Trollor; Henry Brodaty; Yue Cui; Jiyang Jiang; Nicole A Kochan; Darren M Lipnicki; Wei Wen
Longitudinal changes in sulcal morphology associated with late-life aging and MCI.
Perminder S Sachdev; Mamta Sidhu; Melissa Slavin; Wei Wen; Henry Brodaty; John Crawford; Kristan Kang; Nicole Kochan; Charlene Levitan; Karen A Mather; Robyn Richmond
The Sydney Centenarian Study: methodology and profile of centenarians and near-centenarians.
Perminder S Sachdev; Nady Braidy; Lin Zhuang; Wei Wen
Is Alzheimer's a disease of the white matter?

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2013: Tao Liu; Simone Reppermund; Perminder S Sachdev; Julian N Trollor; Henry Brodaty; Yue Cui; Jiyang Jiang; Nicole A Kochan; Darren M Lipnicki; Wei Wen
Longitudinal changes in sulcal morphology associated with late-life aging and MCI.
NeuroImage 2013;74():337-42.
2013: Perminder S Sachdev; Mamta Sidhu; Melissa Slavin; Wei Wen; Henry Brodaty; John Crawford; Kristan Kang; Nicole Kochan; Charlene Levitan; Karen A Mather; Robyn Richmond
The Sydney Centenarian Study: methodology and profile of centenarians and near-centenarians.
International psychogeriatrics / IPA 2013;25(6):993-1005.
2013: Perminder S Sachdev; Nady Braidy; Lin Zhuang; Wei Wen
Is Alzheimer's a disease of the white matter?
Current opinion in psychiatry 2013;26(3):244-51.
2013: Perminder S Sachdev; Melissa J Slavin; Julian N Trollor; Wei Wen; Henry Brodaty; John Crawford; Brian Draper; Kristan Kang; Nicole A Kochan; Darren M Lipnicki; Ora Lux; Karen A Mather; Simone Reppermund
Factors predicting reversion from mild cognitive impairment to normal cognitive functioning: a population-based study.
PloS one 2013;8(3):e59649.
2013: Lin Zhuang; Henry Brodaty; Nicole A Kochan; Simone Reppermund; Perminder S Sachdev; Julian N Trollor; Wei Wen
Microstructural white matter changes, not hippocampal atrophy, detect early amnestic mild cognitive impairment.
PloS one 2013;8(3):e58887.
2013: Sri C Kanchibhotla; John B J Kwok; Karen A Mather; Peter R Schofield; Wei Wen; Perminder S Sachdev
Genetics of ageing-related changes in brain white matter integrity - a review.
Ageing research reviews 2013;12(1):391-401.
2012: Senthil Thillainadesan; Julian N Trollor; Wei Wen; Lin Zhuang; Henry Brodaty; John Crawford; Nicole Kochan; Simone Reppermund; Melissa Slavin; Perminder Sachdev
Changes in mild cognitive impairment and its subtypes as seen on diffusion tensor imaging.
International psychogeriatrics / IPA 2012;24(9):1483-93.
2012: Seyed Amir Hossein Batouli; Perminder S Sachdev; Chao Suo; Wei Wen; Margaret J Wright; David Ames; Julian N Trollor
The heritability of brain metabolites on proton magnetic resonance spectroscopy in older individuals.
NeuroImage 2012;62(1):281-9.
2012: Jacqueline J Zheng; Jacqueline C T Close; Kim Delbaere; Perminder S Sachdev; Wei Wen; Stephen R Lord
White matter hyperintensities and impaired choice stepping reaction time in older people.
Neurobiology of aging 2012;33(7):1177-85.
2012: Wanlin Zhu; Kaarin J Anstey; Yong He; Wei Wen; Aihua Xia; Perminder Sachdev
Changing topological patterns in normal aging using large-scale structural networks.
Neurobiology of aging 2012;33(5):899-913.
2012: Haobo Zhang; Wanlin Zhu; Wei Wen; Henry Brodaty; John D Crawford; Brian Draper; Kristan Kang; Nicole A Kochan; Simone Reppermund; Perminder S Sachdev; Melissa J Slavin; Julian N Trollor
Gray matter atrophy patterns of mild cognitive impairment subtypes.
Journal of the neurological sciences 2012;315(1-2):26-32.
2012: Yue Cui; Jesse S Jin; Nicole A Kochan; Darren M Lipnicki; Tao Liu; Suhuai Luo; Simone Reppermund; Perminder S Sachdev; Julian N Trollor; Henry Brodaty; Wanlin Zhu; Wei Wen
Predicting the development of mild cognitive impairment: a new use of pattern recognition.
NeuroImage 2012;60(2):894-901.
2012: Fei Song; Wei Wen; George A Smythe; Henry Brodaty; Barbara Cameron; John Crawford; Nicole A Kochan; Ora Lux; Karen Mather; Anne Poljak; Perminder S Sachdev
Plasma apolipoprotein levels are associated with cognitive status and decline in a community cohort of older individuals.
PloS one 2012;7(6):e34078.
2012: Jacqueline J J Zheng; Perminder Sachdev; Wei Wen; Henry Brodaty; Jacqueline C T Close; Kim Delbaere; Stephen R Lord
White matter hyperintensities are an independent predictor of physical decline in community-dwelling older people.
Gerontology 2012;58(5):398-406.
2012: Lin Zhuang; Julian N Trollor; Wei Wen; Henry Brodaty; Nicole A Kochan; Simone Reppermund; Perminder Sachdev
Abnormalities of the fornix in mild cognitive impairment are related to episodic memory loss.
Journal of Alzheimer's disease : JAD 2012;29(3):629-39.
2011: Nicole A Kochan; Michael Breakspear; Henry Brodaty; John D Crawford; Melissa Slavin; Julian N Trollor; Andrew Turner; Michael Valenzuela; Wei Wen; Perminder S Sachdev
Cortical responses to a graded working memory challenge predict functional decline in mild cognitive impairment.
Biological psychiatry 2011;70(2):123-30.
2011: Tao Liu; Wei Wen; Wanlin Zhu; Nicole A Kochan; Julian N Trollor; Simone Reppermund; Jesse S Jin; Suhuai Luo; Henry Brodaty; Perminder S Sachdev
The relationship between cortical sulcal variability and cognitive performance in the elderly.
NeuroImage 2011;56(3):865-73.
2011: Haobo Zhang; Julian N Trollor; Wei Wen; Wanlin Zhu; John D Crawford; Nicole A Kochan; Melissa Slavin; Henry Brodaty; Simone Reppermund; Kristan Kang; Karen A Mather; Perminder S Sachdev
Grey matter atrophy of basal forebrain and hippocampus in mild cognitive impairment.
Journal of neurology, neurosurgery, and psychiatry 2011;82(5):487-93.
2011: Prapti Gautam; Nicolas Cherbuin; Perminder S Sachdev; Wei Wen; Kaarin J Anstey
Relationships between cognitive function and frontal grey matter volumes and thickness in middle aged and early old-aged adults: the PATH Through Life Study.
NeuroImage 2011;55(3):845-55.
2011: Wei Wen; Wanlin Zhu; Yong He; Nicole A Kochan; Simone Reppermund; Melissa Slavin; Henry Brodaty; John Crawford; Aihua Xia; Perminder Sachdev
Discrete neuroanatomical networks are associated with specific cognitive abilities in old age.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(4):1204-12.
2010: Lin Zhuang; Wei Wen; Wanlin Zhu; Julian N Trollor; Nicole Kochan; John Crawford; Simone Reppermund; Henry Brodaty; Perminder Sachdev
White matter integrity in mild cognitive impairment: a tract-based spatial statistics study.
NeuroImage 2010;53(1):16-25.
2010: David Bunce; Kaarin J Anstey; Nicolas Cherbuin; Richard Burns; Helen christensen; Wei Wen; Perminder S Sachdev
Cognitive deficits are associated with frontal and temporal lobe white matter lesions in middle-aged adults living in the community.
PloS one 2010;5(10):e13567.
2010: Im Quah-Smith; Perminder S Sachdev; Wei Wen; Xiaohua Chen; Mark A Williams
The brain effects of laser acupuncture in healthy individuals: an FMRI investigation.
PloS one 2010;5(9):e12619.
2010: Ali Javadapour; Gin S Malhi; Belinda Ivanovski; Xiaohua Chen; Wei Wen; Perminder Sachdev
Hippocampal volumes in adults with bipolar disorder.
The Journal of neuropsychiatry and clinical neurosciences 2010;22(1):55-62.
2009: Perminder S Sachdev; Andrea Lammel; Julian N Trollor; Teresa Lee; Margaret J Wright; David Ames; Wei Wen; Nicholas G Martin; Henry Brodaty; Peter R Schofield
A comprehensive neuropsychiatric study of elderly twins: the Older Australian Twins Study.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2009;12(6):573-82.
2009: Jeffrey Chee Leong Looi; Vanessa Tatham; Rajeev Kumar; Jerome J Maller; Ellen Millard; Wei Wen; Xiaohua Chen; Henry Brodaty; Perminder Sachdev
Caudate nucleus volumes in stroke and vascular dementia.
Psychiatry research 2009;174(1):67-75.
2009: Xiaohua Chen; Wei Wen; Kaarin J Anstey; Perminder S Sachdev
Prevalence, incidence, and risk factors of lacunar infarcts in a community sample.
Neurology 2009;73(4):266-72.
2009: Terence C Chua; Wei Wen; Xiaohua Chen; Nicole Kochan; Melissa Slavin; Julian N Trollor; Henry Brodaty; Perminder S Sachdev
Diffusion tensor imaging of the posterior cingulate is a useful biomarker of mild cognitive impairment.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009;17(7):602-13.
2009: Perminder S Sachdev; Ruth A Parslow; Wei Wen; Kaarin J Anstey; Simon Easteal
Sex differences in the causes and consequences of white matter hyperintensities.
Neurobiology of aging 2009;30(6):946-56.
2009: Wei Wen; Perminder S Sachdev; Jason J Li; Xiaohua Chen; Kaarin J Anstey
White matter hyperintensities in the forties: their prevalence and topography in an epidemiological sample aged 44-48.
Human brain mapping 2009;30(4):1155-67.
2009: Helen christensen; Philip Batterham; Andrew Mackinnon; Kaarin J Anstey; Wei Wen; Perminder S Sachdev
Education, atrophy, and cognitive change in an epidemiological sample in early old age.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009;17(3):218-26.
2008: Rajeev Kumar; Kaarin J Anstey; Nicolas Cherbuin; Wei Wen; Perminder S Sachdev
Association of type 2 diabetes with depression, brain atrophy, and reduced fine motor speed in a 60- to 64-year-old community sample.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008;16(12):989-98.
2008: Perminder S Sachdev; Xiaohua Chen; Wei Wen; Kaarin J Anstey; Kaarin J Anstry
Light to moderate alcohol use is associated with increased cortical gray matter in middle-aged men: a voxel-based morphometric study.
Psychiatry research 2008;163(1):61-9.
2008: Nicolas Cherbuin; Kaarin J Anstey; Perminder S Sachdev; Jerome Maller; Chantal Meslin; Holly A Mack; Wei Wen; Simon Easteal
Total and regional gray matter volume is not related to APOE*E4 status in a community sample of middle-aged individuals.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(5):501-4.
2008: Perminder Sachdev; Xiaohua Chen; Wei Wen
White matter hyperintensities in mid-adult life.
Current opinion in psychiatry 2008;21(3):268-74.
2008: Terence C Chua; Wei Wen; Melissa Slavin; Perminder S Sachdev
Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review.
Current opinion in neurology 2008;21(1):83-92.
2008: Michael J Valenzuela; Perminder Sachdev; Wei Wen; Xiaohua Chen; Henry Brodaty
Lifespan mental activity predicts diminished rate of hippocampal atrophy.
PloS one 2008;3(7):e2598.
2008: Perminder Sachdev; Naresh Mondraty; Wei Wen; Kylie Gulliford
Brains of anorexia nervosa patients process self-images differently from non-self-images: an fMRI study.
Neuropsychologia 2008;46(8):2161-8.
2007: Jerome Maller; Kaarin J Anstey; Chantal Réglade-Meslin; Helen christensen; Wei Wen; Perminder Sachdev
Hippocampus and amygdala volumes in a random community-based sample of 60-64 year olds and their relationship to cognition.
Psychiatry research 2007;156(3):185-97.
2007: Ali Javadapour; Gin S Malhi; Belinda Ivanovski; Xiaohua Chen; Wei Wen; Perminder Sachdev
Increased anterior cingulate cortex volume in bipolar I disorder.
The Australian and New Zealand journal of psychiatry 2007;41(11):910-6.
2007: Perminder S Sachdev; Xiaohua Chen; Amy Joscelyne; Wei Wen; Annette Altendorf; Henry Brodaty
Hippocampal size and dementia in stroke patients: the Sydney stroke study.
Journal of the neurological sciences 2007;260(1-2):71-7.
2007: Xiaohua Chen; Perminder S Sachdev; Wei Wen; Kaarin J Anstey
Sex differences in regional gray matter in healthy individuals aged 44-48 years: a voxel-based morphometric study.
NeuroImage 2007;36(3):691-9.
2007: Perminder S Sachdev; Xiaohua Chen; Amy Joscelyne; Wei Wen; Henry Brodaty
Amygdala in stroke/transient ischemic attack patients and its relationship to cognitive impairment and psychopathology: the Sydney Stroke Study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007;15(6):487-96.
2007: Xiaohua Chen; Wei Wen; Gin S Malhi; Belinda Ivanovski; Perminder S Sachdev
Regional gray matter changes in bipolar disorder: a voxel-based morphometric study.
The Australian and New Zealand journal of psychiatry 2007;41(4):327-36.
2007: Perminder Sachdev; Wei Wen; Xiaohua Chen; Henry Brodaty
Progression of white matter hyperintensities in elderly individuals over 3 years.
Neurology 2007;68(3):214-22.
2007: Gin S Malhi; Belinda Ivanovski; Wei Wen; Jim Lagopoulos; K Moss; Perminder Sachdev
Measuring mania metabolites: a longitudinal proton spectroscopy study of hypomania.
Acta psychiatrica Scandinavica. Supplementum 2007;(434):57-66.
2006: Amy J Ross; Perminder S Sachdev; Wei Wen; Henry Brodaty; Amy Joscelyne; Lisa M Lorentz
Prediction of cognitive decline after stroke using proton magnetic resonance spectroscopy.
Journal of the neurological sciences 2006;251(1-2):62-9.
2006: Xiaohua Chen; Wei Wen; Kaarin J Anstey; Perminder S Sachdev
Effects of cerebrovascular risk factors on gray matter volume in adults aged 60-64 years: a voxel-based morphometric study.
Psychiatry research 2006;147(2-3):105-14.
2006: Julian N Trollor; Perminder S Sachdev; Walter Haindl; Henry Brodaty; Wei Wen; Brenda M Walker
Combined cerebral blood flow effects of a cholinergic agonist (milameline) and a verbal recognition task in early Alzheimer's disease.
Psychiatry and clinical neurosciences 2006;60(5):616-25.
2006: Kaarin J Anstey; Anthony Jorm; Chantal Réglade-Meslin; Jerome Maller; Rajeev Kumar; Chwee von Sanden; Timothy D Windsor; Bryan Rodgers; Wei Wen; Perminder Sachdev
Weekly alcohol consumption, brain atrophy, and white matter hyperintensities in a community-based sample aged 60 to 64 years.
Psychosomatic medicine 2006;68(5):778-85.
2006: Amy J Ross; Perminder S Sachdev; Wei Wen; Henry Brodaty
Longitudinal changes during aging using proton magnetic resonance spectroscopy.
The journals of gerontology. Series A, Biological sciences and medical sciences 2006;61(3):291-8.
2006: Wei Wen; Perminder S Sachdev; Xiaohua Chen; Kaarin J Anstey
Gray matter reduction is correlated with white matter hyperintensity volume: a voxel-based morphometric study in a large epidemiological sample.
NeuroImage 2006;29(4):1031-9.
2006: Lee-Fay Low; Kaarin J Anstey; Jerome Maller; Rajeev Kumar; Wei Wen; Ora Lux; Chris Salonikas; Daya Naidoo; Perminder Sachdev
Hormone replacement therapy, brain volumes and white matter in postmenopausal women aged 60-64 years.
Neuroreport 2006;17(1):101-4.
2006: Perminder S Sachdev; Kaarin J Anstey; Ruth A Parslow; Wei Wen; Jerome Maller; Rajeev Kumar; Helen christensen; Anthony Jorm
Pulmonary function, cognitive impairment and brain atrophy in a middle-aged community sample.
Dementia and geriatric cognitive disorders 2006;21(5-6):300-8.
2006: Perminder S Sachdev; Henry Brodaty; Michael J Valenzuela; Lisa Lorentz; J C L Looi; K Berman; A Ross; Wei Wen; Alessandro Stefano Zagami
Clinical determinants of dementia and mild cognitive impairment following ischaemic stroke: the Sydney Stroke Study.
Dementia and geriatric cognitive disorders 2006;21(5-6):275-83.
2006: Julian N Trollor; Perminder S Sachdev; Walter Haindl; Henry Brodaty; Wei Wen; Brenda M Walker
A high-resolution single photon emission computed tomography study of verbal recognition memory in Alzheimer's disease.
Dementia and geriatric cognitive disorders 2006;21(4):267-74.
2005: Amy J Ross; Perminder S Sachdev; Wei Wen; Michael J Valenzuela; Henry Brodaty
Cognitive correlates of 1H MRS measures in the healthy elderly brain.
Brain research bulletin 2005;66(1):9-16.
2005: Julian N Trollor; Perminder S Sachdev; Walter Haindl; Henry Brodaty; Wei Wen; Brenda M Walker
Regional cerebral blood flow deficits in mild Alzheimer's disease using high resolution single photon emission computerized tomography.
Psychiatry and clinical neurosciences 2005;59(3):280-90.
2005: Amy J Ross; Perminder S Sachdev; Wei Wen; Michael J Valenzuela; Henry Brodaty
1H MRS in stroke patients with and without cognitive impairment.
Neurobiology of aging 2005;26(6):873-82.
2005: Perminder S Sachdev; Ruth A Parslow; Ora Lux; Chris Salonikas; Wei Wen; Daya Naidoo; Helen christensen; Anthony Jorm
Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample.
Psychological medicine 2005;35(4):529-38.
2005: Anthony Jorm; Kaarin J Anstey; Helen christensen; Gregory de Plater; Rajeev Kumar; Wei Wen; Perminder Sachdev
MRI hyperintensities and depressive symptoms in a community sample of individuals 60-64 years old.
The American journal of psychiatry 2005;162(4):699-705.
2004: Kaarin J Anstey; Jerome Maller; Chantal Meslin; Helen christensen; Anthony Jorm; Wei Wen; Perminder Sachdev
Hippocampal and amygdalar volumes in relation to handedness in adults aged 60-64.
Neuroreport 2004;15(18):2825-9.
2004: Wei Wen; Perminder S Sachdev
Extent and distribution of white matter hyperintensities in stroke patients: the Sydney Stroke Study.
Stroke; a journal of cerebral circulation 2004;35(12):2813-9.
2004: Anthony Jorm; Peter Butterworth; Kaarin J Anstey; Helen christensen; Simon Easteal; J Maller; K A Mather; Rust Turakulov; Wei Wen; Perminder Sachdev
Memory complaints in a community sample aged 60-64 years: associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities.
Psychological medicine 2004;34(8):1495-506.
2004: Perminder Sachdev; Ruth A Parslow; Chris Salonikas; Ora Lux; Wei Wen; Rajeev Kumar; Daya Naidoo; Helen christensen; Anthony Jorm
Homocysteine and the brain in midadult life: evidence for an increased risk of leukoaraiosis in men.
Archives of neurology 2004;61(9):1369-76.
2004: Wei Wen; Perminder Sachdev
The topography of white matter hyperintensities on brain MRI in healthy 60- to 64-year-old individuals.
NeuroImage 2004;22(1):144-54.
2004: Wei Wen; Perminder Sachdev; Ron Shnier; Henry Brodaty
Effect of white matter hyperintensities on cortical cerebral blood volume using perfusion MRI.
NeuroImage 2004;21(4):1350-6.
2004: Perminder S Sachdev; Henry Brodaty; Michael J Valenzuela; Lisa Lorentz; J C L Looi; Wei Wen; Alessandro Stefano Zagami
The neuropsychological profile of vascular cognitive impairment in stroke and TIA patients.
Neurology 2004;62(6):912-9.
2004: Perminder Sachdev; Wei Wen; Ron Shnier; Henry Brodaty
Cerebral blood volume in T2-weighted white matter hyperintensities using exogenous contrast based perfusion MRI.
The Journal of neuropsychiatry and clinical neurosciences 2004;16(1):83-92.
2003: Colleen K Loo; Perminder S Sachdev; Walter Haindl; Wei Wen; Philip B Mitchell; Vanessa Croker; Gin S Malhi
High (15 Hz) and low (1 Hz) frequency transcranial magnetic stimulation have different acute effects on regional cerebral blood flow in depressed patients.
Psychological medicine 2003;33(6):997-1006.
2003: Michael J Valenzuela; Megan Jones; Wei Wen; Caroline Rae; Scott Graham; Ron Shnier; Perminder Sachdev
Memory training alters hippocampal neurochemistry in healthy elderly.
Neuroreport 2003;14(10):1333-7.
2003: Eva A Feredoes; Perminder S Sachdev; Wei Wen
Disruption of the neural correlates of working memory using high- and low-frequency repetitive transcranial magnetic stimulation: a negative study.
Supplements to Clinical neurophysiology 2003;56():187-97.
2003: Colleen K Loo; Philip B Mitchell; Vanessa Croker; Gin S Malhi; Wei Wen; Simon C Gandevia; Perminder S Sachdev
Double-blind controlled investigation of bilateral prefrontal transcranial magnetic stimulation for the treatment of resistant major depression.
Psychological medicine 2003;33(1):33-40.
2001: Perminder Sachdev; Julian N Trollor; A Walker; Wei Wen; M Fulham; J S Smith; J Matheson
Bilateral orbitomedial leucotomy for obsessive-compulsive disorder: a single-case study using positron emission tomography.
The Australian and New Zealand journal of psychiatry 2001;35(5):684-90.
2000: Michael J Valenzuela; Perminder S Sachdev; Wei Wen; Ron Shnier; Henry Brodaty; D Gillies
Dual voxel proton magnetic resonance spectroscopy in the healthy elderly: subcortical-frontal axonal N-acetylaspartate levels are correlated with fluid cognitive abilities independent of structural brain changes.
NeuroImage 2000;12(6):747-56.
1999: Perminder Sachdev; S Cathcart; Ron Shnier; Wei Wen; Henry Brodaty
Reliability and validity of ratings of signal hyperintensities on MRI by visual inspection and computerised measurement.
Psychiatry research 1999;92(2-3):103-15.