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Roland Wenger

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Muriel R Kaufmann; Peter Schraml; Roland H Wenger; Thomas Hermanns; Gieri Camenisch
Onconeuronal antigen Cdr2 correlates with HIF prolyl-4-hydroxylase PHD1 and worse prognosis in renal cell carcinoma.
Simon Wrann; Renato Wirthner; Muriel R Kaufmann; Daniel P Stiehl; Roland H Wenger
HIF mediated and DNA damage independent histone H2AX phosphorylation in chronic hypoxia.
Muriel R Kaufmann; Uwe Konietzko; Reiner Kunze; Hugo H Marti; Ulrike Müller; Sandra Barth; Gieri Camenisch; Sascha Egger; Meike Hick; Bei Wu; Roland H Wenger
Dysregulation of hypoxia-inducible factor by presenilin/γ-secretase loss-of-function mutations.

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2013: Muriel R Kaufmann; Peter Schraml; Roland H Wenger; Thomas Hermanns; Gieri Camenisch
Onconeuronal antigen Cdr2 correlates with HIF prolyl-4-hydroxylase PHD1 and worse prognosis in renal cell carcinoma.
Experimental and molecular pathology 2013;94(3):453-7.
2013: Simon Wrann; Renato Wirthner; Muriel R Kaufmann; Daniel P Stiehl; Roland H Wenger
HIF mediated and DNA damage independent histone H2AX phosphorylation in chronic hypoxia.
Biological chemistry 2013;394(4):519-28.
2013: Muriel R Kaufmann; Uwe Konietzko; Reiner Kunze; Hugo H Marti; Ulrike Müller; Sandra Barth; Gieri Camenisch; Sascha Egger; Meike Hick; Bei Wu; Roland H Wenger
Dysregulation of hypoxia-inducible factor by presenilin/γ-secretase loss-of-function mutations.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(5):1915-26.
2012: Gunther Boysen; Igor Cima; Niklaus Fankhauser; Thomas Hermanns; Barbara Ingold-Heppner; Wilhelm Krek; Van-Duc Luu; Anna M Nowicka; Peter Schraml; Daniel Stiehl; Tullio Sulser; Claudio R Thoma; Adriana von Teichman; Roland H Wenger; Bernd Wollscheid; Damaris Bausch-Fluck; Holger Moch
Identification and functional characterization of pVHL-dependent cell surface proteins in renal cell carcinoma.
Neoplasia (New York, N.Y.) 2012;14(6):535-46.
2012: Daniel Stiehl; K Wollenick; I Abreu-Rodríguez; M R Bordoli; K Gradin; G Kristiansen; L Poellinger; P Schraml; Roland H Wenger
Non-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop.
Oncogene 2012;31(18):2283-97.
2012: Kristin Wollenick; Roland H Wenger; Utta Berchner-Pfannschmidt; Joachim Fandrey; Jun Hu; Glen Kristiansen; Hubert Rehrauer; Peter Schraml; Daniel Stiehl
Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.
Nucleic acids research 2012;40(5):1928-43.
2011: Katarzyna J Nytko; Nobuyo Maeda; Philipp Schläfli; Patrick Spielmann; Roland H Wenger; Daniel Stiehl
Vitamin C is dispensable for oxygen sensing in vivo.
Blood 2011;117(20):5485-93.
2011: Philipp Schläfli; Juliane Tröger; Katrin Eckhardt; Emanuela Borter; Patrick Spielmann; Roland H Wenger
Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN.
The FEBS journal 2011;278(10):1757-68.
2011: M R Bordoli; Daniel Stiehl; Lubor Borsig; G Kristiansen; S Hausladen; P Schraml; Roland H Wenger; Gieri Camenisch
Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.
Oncogene 2011;30(5):548-60.
2011: Anu Sharma; Roland H Wenger; Lotta von Boehmer; Beata Bode; Alexander Knuth; Kuno Lehmann; Holger Moch; Alessandro A Sartori; Maries van den Broek
γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo.
PloS one 2011;6(11):e28217.
2011: Philippe A Hasgall; David Hoogewijs; Vikram Govind Panse; Roland H Wenger; Marius B Faza; Gieri Camenisch
The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation.
PloS one 2011;6(7):e22107.
2011: Reto A Wildhaber; François Verrey; Roland H Wenger
A graphical simulation software for instruction in cardiovascular mechanics physiology.
Biomedical engineering online 2011;10():8.
2010: Roland H Wenger; David Hoogewijs
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells.
American journal of physiology. Renal physiology 2010;298(6):F1287-96.
2009: Mariola Kurowska-Stolarska; Jörg H W Distler; Astrid Jüngel; Weronika Rudnicka; Elena Neumann; Thomas Pap; Roland H Wenger; Beat A Michel; Ulf Müller-Ladner; Renate E Gay; Wlodzimierz Maslinski; Steffen GAY; Oliver Distler
Inhibitor of DNA binding/differentiation 2 induced by hypoxia promotes synovial fibroblast-dependent osteoclastogenesis.
Arthritis and rheumatism 2009;60(12):3663-75.
2009: Kuppusamy Balamurugan; V-D Luu; M R Kaufmann; V S Hofmann; G Boysen; Sandra Barth; M R Bordoli; Daniel Stiehl; Holger Moch; P Schraml; Roland H Wenger; Gieri Camenisch
Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response.
Oncogene 2009;28(37):3274-85.
2009: Sandra Barth; Frank Edlich; Utta Berchner-Pfannschmidt; Silke Gneuss; Günther Jahreis; Philippe A Hasgall; Joachim Fandrey; Roland H Wenger; Gieri Camenisch
Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.
The Journal of biological chemistry 2009;284(34):23046-58.
2009: P Schläfli; Emanuela Borter; Patrick Spielmann; Roland H Wenger
The PAS-domain kinase PASKIN: a new sensor in energy homeostasis.
Cellular and molecular life sciences : CMLS 2009;66(5):876-83.
2009: Roland H Wenger; Gieri Camenisch; Daniel Stiehl; Dörthe M Katschinski
HIF prolyl-4-hydroxylase interacting proteins: consequences for drug targeting.
Current pharmaceutical design 2009;15(33):3886-94.
2008: Renato Wirthner; Simon Wrann; Kuppusamy Balamurugan; Roland H Wenger; Daniel Stiehl
Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts.
Carcinogenesis 2008;29(12):2306-16.
2007: Jens Köditz; Jutta Nesper; Marieke Wottawa; Daniel Stiehl; Gieri Camenisch; Corinna Franke; Johanna Myllyharju; Roland H Wenger; Dörthe M Katschinski
Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor.
Blood 2007;110(10):3610-7.
2007: Beate Rassler; Grit Marx; Christian Reissig; Marc A Rohling; Andrea Tannapfel; Roland H Wenger; Heinz-Gerd Zimmer
Time course of hypoxia-induced lung injury in rats.
Respiratory physiology & neurobiology 2007;159(1):45-54.
2007: Katarzyna J Nytko; Patrick Spielmann; Gieri Camenisch; Roland H Wenger; Daniel Stiehl
Regulated function of the prolyl-4-hydroxylase domain (PHD) oxygen sensor proteins.
Antioxidants & redox signaling 2007;9(9):1329-38.
2007: Sandra Barth; Jutta Nesper; Philippe A Hasgall; Renato Wirthner; Katarzyna J Nytko; Frank Edlich; Dörthe M Katschinski; Daniel Stiehl; Roland H Wenger; Gieri Camenisch
The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
Molecular and cellular biology 2007;27(10):3758-68.
2007: Javorina Milosevic; Martina Maisel; Florian Wegner; Julia Leuchtenberger; Roland H Wenger; Manfred Gerlach; Alexander Storch; Johannes Schwarz
Lack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(2):412-21.
2007: Renato Wirthner; Kuppusamy Balamurugan; Daniel Stiehl; Sandra Barth; Patrick Spielmann; Felix Oehme; Ingo Flamme; Dörthe M Katschinski; Roland H Wenger; Gieri Camenisch
Determination and modulation of prolyl-4-hydroxylase domain oxygen sensor activity.
Methods in enzymology 2007;435():43-60.
2007: Katrin Eckhardt; Juliane Troger; Jana Reissmann; Dörthe M Katschinski; Klaus F Wagner; Petra Stengel; Uwe Paasch; Peter Hunziker; Emanuela Borter; Sandra Barth; Philipp Schlafli; Patrick Spielmann; Daniel Stiehl; Gieri Camenisch; Roland H Wenger
Male germ cell expression of the PAS domain kinase PASKIN and its novel target eukaryotic translation elongation factor eEF1A1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(1-4):227-40.
2007: Emanuela Borter; Markus Niessen; Richard A Zuellig; Giatgen A Spinas; Patrick Spielmann; Gieri Camenisch; Roland H Wenger
Glucose-stimulated insulin production in mice deficient for the PAS kinase PASKIN.
Diabetes 2007;56(1):113-7.
2006: Dmitriy Lukashev; Boris Klebanov; Hidefumi Kojima; Alex Grinberg; Akio Ohta; Ludmilla Berenfeld; Roland H Wenger; Akio Ohta; Michail V Sitkovsky
Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):4962-5.
2006: Daniel Stiehl; Renato Wirthner; Jens Köditz; Patrick Spielmann; Gieri Camenisch; Roland H Wenger
Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system.
The Journal of biological chemistry 2006;281(33):23482-91.
2006: Sonja Hägele; Babak Behnam; Emanuela Borter; Jonathan Wolfe; Uwe Paasch; Dmitriy Lukashev; Michail V Sitkovsky; Roland H Wenger; Dörthe M Katschinski
TSGA10 prevents nuclear localization of the hypoxia-inducible factor (HIF)-1alpha.
FEBS letters 2006;580(15):3731-8.
2006: Roland H Wenger
Mitochondria: oxygen sinks rather than sensors?
Medical hypotheses 2006;66(2):380-3.
2005: Nadia O Ibrahim; Torsten Hahn; Corinna Franke; Daniel Stiehl; Renato Wirthner; Roland H Wenger; Dörthe M Katschinski
Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors.
Cancer research 2005;65(23):11094-100.
2005: Roland H Wenger; Daniel Stiehl; Gieri Camenisch
Integration of oxygen signaling at the consensus HRE.
Science's STKE : signal transduction knowledge environment 2005;2005(306):re12.
2005: Roland H Wenger; Dörthe M Katschinski
The hypoxic testis and post-meiotic expression of PAS domain proteins.
Seminars in cell & developmental biology 2005;16(4-5):547-53.
2005: Falk Martin; Tobias Linden; Dörthe M Katschinski; Felix Oehme; Ingo Flamme; Chinmay K Mukhopadhyay; Katrin Eckhardt; Juliane Tröger; Sandra Barth; Gieri Camenisch; Roland H Wenger
Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.
Blood 2005;105(12):4613-9.
2004: Roland H Wenger
[Oxygen homeostasis in tissues and cells: how hypoxia regulates gene expression].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2004;39 Suppl 1():S38-43.
2004: Reinhard Depping; Sonja Hägele; Klaus F Wagner; Rudolf J Wiesner; Gieri Camenisch; Roland H Wenger; Dörthe M Katschinski
A dominant-negative isoform of hypoxia-inducible factor-1 alpha specifically expressed in human testis.
Biology of reproduction 2004;71(1):331-9.
2004: Thomas Hofer; Raimo Pohjanvirta; Patrick Spielmann; Matti Viluksela; David P Buchmann; Roland H Wenger; Max Gassmann
Simultaneous exposure of rats to dioxin and carbon monoxide reduces the xenobiotic but not the hypoxic response.
Biological chemistry 2004;385(3-4):291-4.
2004: Dörthe M Katschinski; Lu Le; Susann G Schindler; Tim Thomas; Anne K Voss; Roland H Wenger
Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2004;14(4-6):351-60.
2004: Wilfried Briest; Lars Homagk; Hideo A Baba; Alexander Deten; Beate Rassler; Andrea Tannapfel; Klaus F Wagner; Roland H Wenger; Heinz-Gerd Zimmer
Cardiac remodeling in erythropoietin-transgenic mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2004;14(4-6):277-84.
2004: Alexander Deten; Junpei Shibata; Dimitri Scholz; Wilfried Briest; Klaus F Wagner; Roland H Wenger; Heinz-Gerd Zimmer
Norepinephrine-induced acute heart failure in transgenic mice overexpressing erythropoietin.
Cardiovascular research 2004;61(1):105-14.
2003: Leonhard Schäffer; Annette Scheid; Patrick Spielmann; Christian Breymann; Roland Zimmermann; Martin Meuli; Max Gassmann; Hugo H Marti; Roland H Wenger
Oxygen-regulated expression of TGF-beta 3, a growth factor involved in trophoblast differentiation.
Placenta 2003;24(10):941-50.
2003: Dörthe M Katschinski; Hugo H Marti; Klaus F Wagner; Junpei Shibata; Katrin Eckhardt; Falk Martin; Reinhard Depping; Uwe Paasch; Max Gassmann; Birgit Ledermann; Isabelle Desbaillets; Roland H Wenger
Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN.
Molecular and cellular biology 2003;23(19):6780-9.
2003: Tobias Linden; Roland H Wenger
Iron chelation, angiogenesis and tumor therapy.
International journal of cancer. Journal international du cancer 2003;106(3):458-9.
2003: Junpei Shibata; Jo Hasegawa; Hans-Joachim G Siemens; Eva-Maria Wolber; Leif Dibbelt; Dechun Li; Dörthe M Katschinski; Joachim Fandrey; Wolfgang Jelkmann; Max Gassmann; Roland H Wenger; Klaus F Wagner
Hemostasis and coagulation at a hematocrit level of 0.85: functional consequences of erythrocytosis.
Blood 2003;101(11):4416-22.
2003: Annika Unruh; Anke Ressel; Hamid G Mohamed; Randall S Johnson; Roger Nadrowitz; Eckart Richter; Dörthe M Katschinski; Roland H Wenger
The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.
Oncogene 2003;22(21):3213-20.
2003: Tobias Linden; Dörthe M Katschinski; Katrin Eckhardt; Annette Scheid; Horst Pagel; Roland H Wenger
The antimycotic ciclopirox olamine induces HIF-1alpha stability, VEGF expression, and angiogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):761-3.
2003: Thomas Hofer; Roland H Wenger; Marianne F Kramer; Gloria C Ferreira; Max Gassmann
Hypoxic up-regulation of erythroid 5-aminolevulinate synthase.
Blood 2003;101(1):348-50.
2002: Thomas Hofer; Isabelle Desbaillets; Gisele Höpfl; Roland H Wenger; Max Gassmann
Characterization of HIF-1 alpha overexpressing HeLa cells and implications for gene therapy.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2002;133(4):475-81.
2002: Roland H Wenger
Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1151-62.
2002: Gisele Höpfl; Roland H Wenger; Urs Ziegler; Thomas Stallmach; Olivier Gardelle; Roger Achermann; Melanie Wergin; Barbara Kaser-Hotz; H Mark Saunders; Kaye J Williams; Ian J Stratford; Max Gassmann; Isabelle Desbaillets
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor.
Cancer research 2002;62(10):2962-70.
2002: Dörthe M Katschinski; Lu Le; Daniel Heinrich; Klaus F Wagner; Thomas Hofer; Susann G Schindler; Roland H Wenger
Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity.
The Journal of biological chemistry 2002;277(11):9262-7.
2002: Annette Scheid; Roland H Wenger; Leonhard Schäffer; Isabelle Camenisch; Oliver Distler; Andrej Ferenc; Heidi Cristina; Heather E Ryan; Randall S Johnson; Klaus F Wagner; Urs G Stauffer; Christian Bauer; Max Gassmann; Martin Meuli
Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):411-3.
2002: Daniel Stiehl; Wolfgang Jelkmann; Roland H Wenger; Thomas Hellwig-Bürgel
Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway.
FEBS letters 2002;512(1-3):157-62.
2002: Hugo H Marti; Dörthe M Katschinski; Klaus F Wagner; Leonhard Schäffer; Bettina Stier; Roland H Wenger
Isoform-specific expression of hypoxia-inducible factor-1alpha during the late stages of mouse spermiogenesis.
Molecular endocrinology (Baltimore, Md.) 2002;16(2):234-43.
2002: Gieri Camenisch; Roland H Wenger; Max Gassmann
DNA-binding activity of hypoxia-inducible factors (HIFs).
Methods in molecular biology (Clifton, N.J.) 2002;196():117-29.
2001: D Chilov; Thomas Hofer; Christian Bauer; Roland H Wenger; Max Gassmann
Hypoxia affects expression of circadian genes PER1 and CLOCK in mouse brain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2613-22.
2001: Thomas Hofer; Isabelle Desbaillets; Gisele Höpfl; Max Gassmann; Roland H Wenger
Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2715-7.
2001: Thomas Hofer; Patrick Spielmann; P Stengel; B Stier; Dörthe M Katschinski; Isabelle Desbaillets; Max Gassmann; Roland H Wenger
Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors.
Biochemical and biophysical research communications 2001;288(4):757-64.
2001: Gieri Camenisch; Deborah Stroka; Max Gassmann; Roland H Wenger
Attenuation of HIF-1 DNA-binding activity limits hypoxia-inducible endothelin-1 expression.
Pflügers Archiv : European journal of physiology 2001;443(2):240-9.
2001: Deborah Stroka; T Burkhardt; Isabelle Desbaillets; Roland H Wenger; Desley A H Neil; Christian Bauer; Max Gassmann; Daniel Candinas
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2445-53.
2001: Roland H Wenger; C Bauer
Oxygen sensing: "hydroxy" translates "oxy".
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2001;16():195-6.
2001: U R Jewell; I Kvietikova; Annette Scheid; Christian Bauer; Roland H Wenger; Max Gassmann
Induction of HIF-1alpha in response to hypoxia is instantaneous.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(7):1312-4.
2000: Annette Scheid; Martin Meuli; Max Gassmann; Roland H Wenger
Genetically modified mouse models in studies on cutaneous wound healing.
Experimental physiology 2000;85(6):687-704.
2000: A Görlach; Gieri Camenisch; I Kvietikova; L Vogt; Roland H Wenger; Max Gassmann
Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions.
Biochimica et biophysica acta 2000;1493(1-2):125-34.
2000: R M Wanner; Patrick Spielmann; Deborah Stroka; Gieri Camenisch; Isabelle Camenisch; Annette Scheid; D R Houck; Christian Bauer; Max Gassmann; Roland H Wenger
Epolones induce erythropoietin expression via hypoxia-inducible factor-1 alpha activation.
Blood 2000;96(4):1558-65.
2000: Vojtech Pavlicek; Hugo H Marti; Sibylle Grad; J Simon R Gibbs; C Kol; Roland H Wenger; Max Gassmann; Jana Kohl; FE Maly; Oswald Oelz; Erwin A Koller; Christian Schirlo
Effects of hypobaric hypoxia on vascular endothelial growth factor and the acute phase response in subjects who are susceptible to high-altitude pulmonary oedema.
European journal of applied physiology 2000;81(6):497-503.
2000: Roland H Wenger
Mammalian oxygen sensing, signalling and gene regulation.
The Journal of experimental biology 2000;203(Pt 8):1253-63.
2000: Annette Scheid; Roland H Wenger; H Christina; Isabelle Camenisch; A Ferenc; Urs G Stauffer; Max Gassmann; Martin Meuli
Hypoxia-regulated gene expression in fetal wound regeneration and adult wound repair.
Pediatric surgery international 2000;16(4):232-6.
2000: Max Gassmann; D Chilov; Roland H Wenger
Regulation of the hypoxia-inducible factor-1 alpha. ARNT is not necessary for hypoxic induction of HIF-1 alpha in the nucleus.
Advances in experimental medicine and biology 2000;475():87-99.
1999: D Chilov; Gieri Camenisch; I Kvietikova; Urs Ziegler; Max Gassmann; Roland H Wenger
Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha.
Journal of cell science 1999;112 ( Pt 8)():1203-12.
1999: S Bichet; Roland H Wenger; Gieri Camenisch; A Rolfs; W Ehleben; T Porwol; Helmut Acker; Joachim Fandrey; Christian Bauer; Max Gassmann
Oxygen tension modulates beta-globin switching in embryoid bodies.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(2):285-95.
1999: Gieri Camenisch; M Tini; D Chilov; I Kvietikova; Vickram Srinivas; Jaime Caro; Patrick Spielmann; Roland H Wenger; Max Gassmann
General applicability of chicken egg yolk antibodies: the performance of IgY immunoglobulins raised against the hypoxia-inducible factor 1alpha.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(1):81-8.
1998: Roland H Wenger; Gieri Camenisch; Isabelle Desbaillets; D Chilov; Max Gassmann
Up-regulation of hypoxia-inducible factor-1alpha is not sufficient for hypoxic/anoxic p53 induction.
Cancer research 1998;58(24):5678-80.
1998: Roland H Wenger; Hugo H Marti; C Bauer; Max Gassmann
Optimal erythropoietin expression in human hepatoma cell lines requires activation of multiple signalling pathways.
International journal of molecular medicine 1998;2(3):317-24.
1998: Roland H Wenger; I Kvietikova; A Rolfs; Gieri Camenisch; Max Gassmann
Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site.
European journal of biochemistry / FEBS 1998;253(3):771-7.
1998: Roland H Wenger; A Rolfs; Patrick Spielmann; D R Zimmermann; Max Gassmann
Mouse hypoxia-inducible factor-1alpha is encoded by two different mRNA isoforms: expression from a tissue-specific and a housekeeping-type promoter.
Blood 1998;91(9):3471-80.
1997: A Rolfs; I Kvietikova; Max Gassmann; Roland H Wenger
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1.
The Journal of biological chemistry 1997;272(32):20055-62.
1997: Roland H Wenger; Max Gassmann
Oxygen(es) and the hypoxia-inducible factor-1.
Biological chemistry 1997;378(7):609-16.
1997: Roland H Wenger; A Rolfs; I Kvietikova; Patrick Spielmann; D R Zimmermann; Max Gassmann
The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence.
European journal of biochemistry / FEBS 1997;246(1):155-65.
1997: Max Gassmann; I Kvietikova; A Rolfs; Roland H Wenger
Oxygen- and dioxin-regulated gene expression in mouse hepatoma cells.
Kidney international 1997;51(2):567-74.
1997: I Kvietikova; Roland H Wenger; Hugo H Marti; Max Gassmann
The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsive.
Kidney international 1997;51(2):564-6.
1997: Roland H Wenger; I Kvietikova; A Rolfs; Max Gassmann; Hugo H Marti
Hypoxia-inducible factor-1 alpha is regulated at the post-mRNA level.
Kidney international 1997;51(2):560-3.
1997: Hugo H Marti; Max Gassmann; Roland H Wenger; I Kvietikova; Maria Cristina Morganti-Kossmann; Thomas Kossmann; O Trentz; Christian Bauer
Detection of erythropoietin in human liquor: intrinsic erythropoietin production in the brain.
Kidney international 1997;51(2):416-8.
1996: Gieri Camenisch; M Gruber; G Donoho; P Van Sloun; Roland H Wenger; Max Gassmann
A polyoma-based episomal vector efficiently expresses exogenous genes in mouse embryonic stem cells.
Nucleic acids research 1996;24(19):3707-13.
1996: Katarina Gradin; Jacqueline McGuire; Roland H Wenger; I Kvietikova; M L fhitelaw; Rune Toftgård; L Tora; Max Gassmann; Lorenz Poellinger
Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.
Molecular and cellular biology 1996;16(10):5221-31.
1996: Roland H Wenger; A Rolfs; Hugo H Marti; J L Guénet; Max Gassmann
Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha.
Biochemical and biophysical research communications 1996;223(1):54-9.
1996: Max Gassmann; Joachim Fandrey; S Bichet; Maria Wartenberg; Hugo H Marti; Christian Bauer; Roland H Wenger; Helmut Acker
Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2867-72.
1996: Hugo H Marti; Roland H Wenger; L A Rivas; U Straumann; Murat Digicaylioglu; V Henn; Y Yonekawa; Christian Bauer; Max Gassmann
Erythropoietin gene expression in human, monkey and murine brain.
The European journal of neuroscience 1996;8(4):666-76.
1996: Roland H Wenger; M Gassmann
Little difference.
Nature 1996;380(6570):100.
1996: Roland H Wenger; Hugo H Marti; C C Schuerer-Maly; I Kvietikova; Christian Bauer; Max Gassmann; F E Maly
Hypoxic induction of gene expression in chronic granulomatous disease-derived B-cell lines: oxygen sensing is independent of the cytochrome b558-containing nicotinamide adenine dinucleotide phosphate oxidase.
Blood 1996;87(2):756-61.
1995: I Kvietikova; Roland H Wenger; Hugo H Marti; Max Gassmann
The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site.
Nucleic acids research 1995;23(22):4542-50.
1995: Roland H Wenger; A Rolfs; Hugo H Marti; Christian Bauer; Max Gassmann
Hypoxia, a novel inducer of acute phase gene expression in a human hepatoma cell line.
The Journal of biological chemistry 1995;270(46):27865-70.
1995: Roland H Wenger; M Gassmann
Mitochondria contaminate databases.
Trends in genetics : TIG 1995;11(5):167-8.
1995: Murat Digicaylioglu; S Bichet; Hugo H Marti; Roland H Wenger; L A Rivas; Christian Bauer; Max Gassmann
Localization of specific erythropoietin binding sites in defined areas of the mouse brain.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(9):3717-20.