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Andreas Wenzel

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Marijana Samardzija; Naoyuki Tanimoto; Corinne Kostic; Susanne Beck; Vitus Oberhauser; Sandrine Joly; Markus Thiersch; Edda Fahl; Yvan Arsenijevic; Johannes Von Lintig; Andreas Wenzel; Mathias W Seeliger; Christian grimm, Prof Dr. Phil. Nat.
In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death.
Sandrine Joly; Marijana Samardzija; Andreas Wenzel; Markus Thiersch; Christian grimm, Prof Dr. Phil. Nat.
Nonessential role of beta3 and beta5 integrin subunits for efficient clearance of cellular debris after light-induced photoreceptor degeneration.
Marijana Samardzija; Johannes Von Lintig; Naoyuki Tanimoto; Vitus Oberhauser; Markus Thiersch; Charlotte E Remé; Mathias W Seeliger; Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel
R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.

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All Publications

2009: Marijana Samardzija; Naoyuki Tanimoto; Corinne Kostic; Susanne Beck; Vitus Oberhauser; Sandrine Joly; Markus Thiersch; Edda Fahl; Yvan Arsenijevic; Johannes Von Lintig; Andreas Wenzel; Mathias W Seeliger; Christian grimm, Prof Dr. Phil. Nat.
In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death.
Human molecular genetics 2009;18(7):1266-75.
2009: Sandrine Joly; Marijana Samardzija; Andreas Wenzel; Markus Thiersch; Christian grimm, Prof Dr. Phil. Nat.
Nonessential role of beta3 and beta5 integrin subunits for efficient clearance of cellular debris after light-induced photoreceptor degeneration.
Investigative ophthalmology & visual science 2009;50(3):1423-32.
2008: Marijana Samardzija; Johannes Von Lintig; Naoyuki Tanimoto; Vitus Oberhauser; Markus Thiersch; Charlotte E Remé; Mathias W Seeliger; Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel
R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.
Human molecular genetics 2008;17(2):281-92.
2008: Markus Thiersch; Wolfgang Raffelsberger; Rico Frigg; Marijana Samardzija; Andreas Wenzel; Olivier Poch; Christian grimm, Prof Dr. Phil. Nat.
Analysis of the retinal gene expression profile after hypoxic preconditioning identifies candidate genes for neuroprotection.
BMC genomics 2008;9():73.
2007: Andreas Wenzel; Johannes Von Lintig; Vitus Oberhauser; Naoyuki Tanimoto; Christian grimm, Prof Dr. Phil. Nat.; Mathias W Seeliger
RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice.
Investigative ophthalmology & visual science 2007;48(2):534-42.
2006: Marijana Samardzija; Andreas Wenzel; Markus Thiersch; Rico Frigg; Charlotte E Remé; Christian grimm, Prof Dr. Phil. Nat.
Caspase-1 ablation protects photoreceptors in a model of autosomal dominant retinitis pigmentosa.
Investigative ophthalmology & visual science 2006;47(12):5181-90.
2006: Rico Frigg; Andreas Wenzel; Marijana Samardzija; Bruno Oesch; Hedwig Wariwoda; Alexander A Navarini; Mathias W Seeliger; Naoyuki Tanimoto; Charlotte E Remé; Christian grimm, Prof Dr. Phil. Nat.
The prion protein is neuroprotective against retinal degeneration in vivo.
Experimental eye research 2006;83(6):1350-8.
2006: Marijana Samardzija; Andreas Wenzel; Svenja Aufenberg; Markus Thiersch; Charlotte E Remé; Christian grimm, Prof Dr. Phil. Nat.
Differential role of Jak-STAT signaling in retinal degenerations.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(13):2411-3.
2006: Marijana Samardzija; Andreas Wenzel; M Naash; Charlotte E Remé; Christian grimm, Prof Dr. Phil. Nat.
Rpe65 as a modifier gene for inherited retinal degeneration.
The European journal of neuroscience 2006;23(4):1028-34.
2005: Mathias W Seeliger; Susanne C Beck; Naira Pereyra-Muñoz; Susann Dangel; Jen-Yue Tsai; Ulrich Luhmann; Serge van de Pavert; Jan Wijnholds; Marijana Samardzija; Andreas Wenzel; Eberhart Zrenner; Kristina Narfström; Edda Fahl; Naoyuki Tanimoto; Niyazi Acar; Felix Tonagel
In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy.
Vision research 2005;45(28):3512-9.
2005: Andreas Wenzel; Vitus Oberhauser; Edward N Pugh; Trevor D Lamb; Christian grimm, Prof Dr. Phil. Nat.; Marijana Samardzija; Edda Fahl; Mathias W Seeliger; Charlotte E Remé; Johannes Von Lintig
The retinal G protein-coupled receptor (RGR) enhances isomerohydrolase activity independent of light.
The Journal of biological chemistry 2005;280(33):29874-84.
2005: Christian grimm, Prof Dr. Phil. Nat.; Dirk M Hermann; Anna Bogdanova; S Hotop; Ulkan Kilic; Andreas Wenzel; E Kilic; M Gassmann
Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration.
Seminars in cell & developmental biology 2005;16(4-5):531-8.
2005: Andreas Wenzel; Christian grimm, Prof Dr. Phil. Nat.; Marijana Samardzija; Charlotte E Remé
Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration.
Progress in retinal and eye research 2005;24(2):275-306.
2005: Bo Gao; Robert D Huber; Andreas Wenzel; Stephan R Vavricka; Manfred G Ismair; Charlotte E Remé; Peter J Meier Abt
Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium.
Experimental eye research 2005;80(1):61-72.
2004: Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel; Dinu Stanescu; Marijana Samardzija; Svenja Hotop; Matthias Groszer; Muna Naash; Max Gassmann; Charlotte E Remé
Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(25):5651-8.
2003: Andreas Wenzel; Christian grimm, Prof Dr. Phil. Nat.; Marijana Samardzija; Charlotte E Remé
The genetic modifier Rpe65Leu(450): effect on light damage susceptibility in c-Fos-deficient mice.
Investigative ophthalmology & visual science 2003;44(6):2798-802.
2003: Josef Beatrice; Andreas Wenzel; Charlotte E Remé; Christian grimm, Prof Dr. Phil. Nat.
Increased light damage susceptibility at night does not correlate with RPE65 levels and rhodopsin regeneration in rats.
Experimental eye research 2003;76(6):695-700.
2003: Charlotte E Remé; Christian grimm, Prof Dr. Phil. Nat.; Farhad Hafezi; Hans Peter Iseli; Andreas Wenzel
Why study rod cell death in retinal degenerations and how?
Documenta ophthalmologica. Advances in ophthalmology 2003;106(1):25-9.
2002: Hans Peter Iseli; Andreas Wenzel; Farhad Hafezi; C E REme; Christian grimm, Prof Dr. Phil. Nat.
Light damage susceptibility and RPE65 in rats.
Experimental eye research 2002;75(4):407-13.
2002: Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel; Matthias Groszer; Helmut Mayser; Mathias W Seeliger; Marijana Samardzija; Christian Bauer; Max Gassmann; Charlotte E Remé
HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration.
Nature medicine 2002;8(7):718-24.
2002: Andreas Wenzel; Hans Peter Iseli; Alexander Fleischmann; Farhad Hafezi; Christian grimm, Prof Dr. Phil. Nat.; Erwin F Wagner; Charlotte E Remé
Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis.
Journal of neurochemistry 2002;80(6):1089-94.
2001: Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel; A Behrens; Farhad Hafezi; E F Wagner; Charlotte E Remé
AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun.
Cell death and differentiation 2001;8(8):859-67.
2001: Andreas Wenzel; Christian grimm, Prof Dr. Phil. Nat.; Mathias W Seeliger; Gesine B Jaissle; Farhad Hafezi; R Kretschmer; Eberhart Zrenner; Charlotte E Remé
Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor.
Investigative ophthalmology & visual science 2001;42(7):1653-9.
2001: Andreas Wenzel; C E Reme; TP Williams; Farhad Hafezi; Christian grimm, Prof Dr. Phil. Nat.
The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(1):53-8.
2000: Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel; Farhad Hafezi; S Yu; T Michael Redmond; Charlotte E Remé
Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration.
Nature genetics 2000;25(1):63-6.
2000: N Kueng-Hitz; Christian grimm, Prof Dr. Phil. Nat.; N Lansel; Farhad Hafezi; L He; D A Fox; Charlotte E Remé; Günter Niemeyer; Andreas Wenzel
The retina of c-fos-/- mice: electrophysiologic, morphologic and biochemical aspects.
Investigative ophthalmology & visual science 2000;41(3):909-16.
2000: M Abegg; Farhad Hafezi; Andreas Wenzel; Christian grimm, Prof Dr. Phil. Nat.; Charlotte E Remé
[Therapeutic strategies in RP (retinitis pigmentosa): light at the end of the tunnel?].
Klinische Monatsblätter für Augenheilkunde 2000;216(2):83-9.
2000: Andreas Wenzel; Christian grimm, Prof Dr. Phil. Nat.; A Marti; N Kueng-Hitz; Farhad Hafezi; Günter Niemeyer; Charlotte E Remé
c-fos controls the "private pathway" of light-induced apoptosis of retinal photoreceptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(1):81-8.
1999: Farhad Hafezi; Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel; M Abegg; moshe yaniv; Charlotte E Remé
Retinal photoreceptors are apoptosis-competent in the absence of JunD/AP-1.
Cell death and differentiation 1999;6(10):934-6.
1999: Farhad Hafezi; A Marti; Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel; Charlotte E Remé
Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors.
Vision research 1999;39(15):2511-8.
1998: Farhad Hafezi; M Abegg; Christian grimm, Prof Dr. Phil. Nat.; Andreas Wenzel; K Munz; Jörg Stürmer; D B Farber; Charlotte E Remé
Retinal degeneration in the rd mouse in the absence of c-fos.
Investigative ophthalmology & visual science 1998;39(12):2239-44.
1998: Charlotte E Remé; Christian grimm, Prof Dr. Phil. Nat.; Farhad Hafezi; A Marti; Andreas Wenzel
Apoptotic cell death in retinal degenerations.
Progress in retinal and eye research 1998;17(4):443-64.
1998: Farhad Hafezi; J J Reinboth; Andreas Wenzel; K Munz; Charlotte E Remé
[HPETE, an arachidonic acid metabolite, induces apoptosis in rat retina in vitro].
Klinische Monatsblätter für Augenheilkunde 1998;212(6):469-72.
1998: A Marti; Farhad Hafezi; N Lansel; M E Hegi; Andreas Wenzel; Christian grimm, Prof Dr. Phil. Nat.; Günter Niemeyer; Charlotte E Remé
Light-induced cell death of retinal photoreceptors in the absence of p53.
Investigative ophthalmology & visual science 1998;39(5):846-9.
1997: Andreas Wenzel; Dietmar Benke; Hanns Mohler; Jean-Marc Fritschy
N-methyl-D-aspartate receptors containing the NR2D subunit in the retina are selectively expressed in rod bipolar cells.
Neuroscience 1997;78(4):1105-12.