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Tanja Wenzler

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Chemicals & Drugs

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Moloy Banerjee; Reto Brun; Abdelbasset Farahat; Arvind Kumar; Manoj M Munde; Tanja Wenzler; Karl A Werbovetz; W David Wilson; Xiaohua Zhu; David W Boykin
Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides.
Reem K Arafa; Reto Brun; Yun Chai; Tanja Wenzler; W David Wilson
Molecular modeling study and synthesis of novel dicationic flexible triaryl guanidines and imidamides as antiprotozoal agents.
Abdelbasset Farahat; Ekaterina Paliakov; Arvind Kumar; Alaa-Eldin M Barghash; Fatma E Goda; Hassan M Eisa; Tanja Wenzler; Reto Brun; Yang Liu; W David Wilson; David W Boykin
Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties.

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All Publications

2012: Moloy Banerjee; Reto Brun; Abdelbasset Farahat; Arvind Kumar; Manoj M Munde; Tanja Wenzler; Karl A Werbovetz; W David Wilson; Xiaohua Zhu; David W Boykin
Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides.
European journal of medicinal chemistry 2012;55():449-54.
2011: Reem K Arafa; Reto Brun; Yun Chai; Tanja Wenzler; W David Wilson
Molecular modeling study and synthesis of novel dicationic flexible triaryl guanidines and imidamides as antiprotozoal agents.
European journal of medicinal chemistry 2011;46(12):5852-60.
2011: Abdelbasset Farahat; Ekaterina Paliakov; Arvind Kumar; Alaa-Eldin M Barghash; Fatma E Goda; Hassan M Eisa; Tanja Wenzler; Reto Brun; Yang Liu; W David Wilson; David W Boykin
Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties.
Bioorganic & medicinal chemistry 2011;19(7):2156-67.
2010: Prashanth Athri; Tanja Wenzler; Richard R Tidwell; Svetlana M Bakunova; W David Wilson
Pharmacophore model for pentamidine analogs active against Plasmodium falciparum.
European journal of medicinal chemistry 2010;45(12):6147-51.
2010: Danuta Branowska; Abdelbasset Farahat; Arvind Kumar; Tanja Wenzler; Reto Brun; Yang Liu; W David Wilson; David W Boykin
Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles.
Bioorganic & medicinal chemistry 2010;18(10):3551-8.
2010: Abdelbasset Farahat; Arvind Kumar; Martial Say; Alaa El-Din M Barghash; Fatma E Goda; Hassan M Eisa; Tanja Wenzler; Reto Brun; Yang Liu; Leah Mickelson; W David Wilson; David W Boykin
Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines.
Bioorganic & medicinal chemistry 2010;18(2):557-66.
2010: Stanislav A Bakunov; Svetlana M Bakunova; Tanja Wenzler; Maedot Ghebru; Karl A Werbovetz; Reto Brun; Richard R Tidwell
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles.
Journal of medicinal chemistry 2010;53(1):254-72.
2009: Stanislav A Bakunov; Svetlana M Bakunova; Arlene Bridges; Tanja Wenzler; Todd Barszcz; Karl A Werbovetz; Reto Brun; Richard R Tidwell
Synthesis and antiprotozoal properties of pentamidine congeners bearing the benzofuran motif.
Journal of medicinal chemistry 2009;52(18):5763-7.
2009: Laixing Hu; Reem K Arafa; Mohamed A Ismail; Alpa Patel; Manoj Munde; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum.
Bioorganic & medicinal chemistry 2009;17(18):6651-8.
2009: Donald A Patrick; Stanislav A Bakunov; Svetlana M Bakunova; E V K Suresh Kumar; Heidi Chen; Susan Kilgore Jones; Tanja Wenzler; Todd Barzcz; Karl A Werbovetz; Reto Brun; Richard R Tidwell
Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes.
European journal of medicinal chemistry 2009;44(9):3543-51.
2009: Svetlana M Bakunova; Stanislav A Bakunov; Tanja Wenzler; Todd Barszcz; Karl A Werbovetz; Reto Brun; Richard R Tidwell
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine.
Journal of medicinal chemistry 2009;52(15):4657-67.
2009: Svetlana M Bakunova; Stanislav A Bakunov; Donald A Patrick; E V K Suresh Kumar; Kwasi A Ohemeng; Arlene Bridges; Tanja Wenzler; Todd Barszcz; Susan Kilgore Jones; Karl A Werbovetz; Reto Brun; Richard R Tidwell
Structure-activity study of pentamidine analogues as antiprotozoal agents.
Journal of medicinal chemistry 2009;52(7):2016-35.
2008: Reem K Arafa; Mohamed A Ismail; Manoj Munde; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents.
European journal of medicinal chemistry 2008;43(12):2901-8.
2008: Stanislav A Bakunov; Svetlana M Bakunova; Tanja Wenzler; Todd Barszcz; Karl A Werbovetz; Reto Brun; Richard R Tidwell
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans.
Journal of medicinal chemistry 2008;51(21):6927-44.
2008: Mohamed A Ismail; Reem K Arafa; Tanja Wenzler; Reto Brun; Farial A Tanious; David W. Wilson; David W Boykin
Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.
Bioorganic & medicinal chemistry 2008;16(2):683-91.
2008: Laixing Hu; Reem K Arafa; Mohamed A Ismail; Tanja Wenzler; Reto Brun; Manoj Munde; David W. Wilson; Sandra Nzimiro; Serene Samyesudhas; Karl A Werbovetz; David W Boykin
Azaterphenyl diamidines as antileishmanial agents.
Bioorganic & medicinal chemistry letters 2008;18(1):247-51.
2007: Svetlana M Bakunova; Stanislav A Bakunov; Tanja Wenzler; Todd Barszcz; Karl A Werbovetz; Reto Brun; James Edwin Hall; Richard R Tidwell
Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations.
Journal of medicinal chemistry 2007;50(23):5807-23.
2007: Amanda M Mathis; Arlene Bridges; Mohamed A Ismail; Arvind Kumar; Iris Francesconi; Mariappan Anbazhagan; Qiyue Hu; Farial A Tanious; Tanja Wenzler; Janelle Y Saulter; David W. Wilson; Reto Brun; David W Boykin; Richard R Tidwell; James Edwin Hall
Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in trypanosomes.
Antimicrobial agents and chemotherapy 2007;51(8):2801-10.
2007: Donald A Patrick; Stanislav A Bakunov; Svetlana M Bakunova; E V K Suresh Kumar; Richard J Lombardy; Susan Kilgore Jones; Arlene Bridges; Oksana Zhirnov; James Edwin Hall; Tanja Wenzler; Reto Brun; Richard R Tidwell
Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles.
Journal of medicinal chemistry 2007;50(10):2468-85.
2007: Jose L Gonzalez; Chad E Stephens; Tanja Wenzler; Reto Brun; Farial A Tanious; David W. Wilson; Todd Barszcz; Karl A Werbovetz; David W Boykin
Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes.
European journal of medicinal chemistry 2007;42(4):552-7.
2006: Sarah Chackal-Catoen; Yi Miao; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Dicationic DNA-targeted antiprotozoal agents: naphthalene replacement of benzimidazole.
Bioorganic & medicinal chemistry 2006;14(22):7434-45.
2006: Mohamed A Ismail; Reem K Arafa; Reto Brun; Tanja Wenzler; Yi Miao; David W. Wilson; Claudia Generaux; Arlene Bridges; James Edwin Hall; David W Boykin
Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues.
Journal of medicinal chemistry 2006;49(17):5324-32.
2006: Prashanth Athri; Tanja Wenzler; Patricia Ruiz; Reto Brun; David W Boykin; Richard R Tidwell; David W. Wilson
3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity.
Bioorganic & medicinal chemistry 2006;14(9):3144-52.
2005: Mohamed A Ismail; Adalgisa Batista-Parra; Yi Miao; David W. Wilson; Tanja Wenzler; Reto Brun; David W Boykin
Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents.
Bioorganic & medicinal chemistry 2005;13(24):6718-26.
2005: Reem K Arafa; Reto Brun; Tanja Wenzler; Farial A Tanious; David W. Wilson; Chad E Stephens; David W Boykin
Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs.
Journal of medicinal chemistry 2005;48(17):5480-8.
2004: Mohamed A Ismail; Reto Brun; Tanja Wenzler; Farial A Tanious; David W. Wilson; David W Boykin
Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents.
Bioorganic & medicinal chemistry 2004;12(20):5405-13.
2004: Mohamed A Ismail; Reto Brun; Tanja Wenzler; Farial A Tanious; David W. Wilson; David W Boykin
Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents.
Journal of medicinal chemistry 2004;47(14):3658-64.