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Karl Werdan

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Henning Ebelt; Ina Hillebrand; Sawa Kostin; Ursula Müller-Werdan; Herbert Neuhaus; Elisabeth Schwarz; Karl Werdan; Ying Zhang; Stephan Arlt; Thomas Braun
Treatment with bone morphogenetic protein 2 limits infarct size after myocardial infarction in mice.
Dietrich Stoevesandt; Oliver Thews; Karl Werdan; Rolf-Edgar Silber; Waldemar Herr; Stefan Hettwer; Carsten Klempt; Torsten Kraya; Robert Scheubel; Axel Schlitt
Embolic events caused by aortic thrombi: an underestimated entity?
Marco Metra; Peter S Pang; Piotr Ponikowski; Margaret F Prescott; Rajnish Saini; Christoph Schumacher; Thomas Severin; John R Teerlink; Sam L Teichman; Angelo Trapani; Elaine Unemori; Adriaan A Voors; Karl Werdan; Kirkwood F Adams; Christopher A Bush; Gad Cotter; Beth A Davison; Maria I Dorobantu; Christopher Edwards; G Michael Felker; Gerasimos Filippatos; Barry H Greenberg; Liliana Grinfeld; Guillaume Jondeau; Alon Marmor; Josep Masip
Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes.

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2013: Henning Ebelt; Ina Hillebrand; Sawa Kostin; Ursula Müller-Werdan; Herbert Neuhaus; Elisabeth Schwarz; Karl Werdan; Ying Zhang; Stephan Arlt; Thomas Braun
Treatment with bone morphogenetic protein 2 limits infarct size after myocardial infarction in mice.
Shock (Augusta, Ga.) 2013;39(4):353-60.
2013: Dietrich Stoevesandt; Oliver Thews; Karl Werdan; Rolf-Edgar Silber; Waldemar Herr; Stefan Hettwer; Carsten Klempt; Torsten Kraya; Robert Scheubel; Axel Schlitt
Embolic events caused by aortic thrombi: an underestimated entity?
Journal of thrombosis and thrombolysis 2013;35(2):223-7.
2013: Marco Metra; Peter S Pang; Piotr Ponikowski; Margaret F Prescott; Rajnish Saini; Christoph Schumacher; Thomas Severin; John R Teerlink; Sam L Teichman; Angelo Trapani; Elaine Unemori; Adriaan A Voors; Karl Werdan; Kirkwood F Adams; Christopher A Bush; Gad Cotter; Beth A Davison; Maria I Dorobantu; Christopher Edwards; G Michael Felker; Gerasimos Filippatos; Barry H Greenberg; Liliana Grinfeld; Guillaume Jondeau; Alon Marmor; Josep Masip
Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes.
Journal of the American College of Cardiology 2013;61(2):196-206.
2013: John R Teerlink; Sam L Teichman; Angelo Trapani; Elaine Unemori; Adriaan A Voors; Karl Werdan; Kirkwood F Adams; Christopher A Bush; Gad Cotter; Beth A Davison; Maria I Dorobantu; G Michael Felker; Gerasimos Filippatos; Barry H Greenberg; Liliana Grinfeld; Guillaume Jondeau; Alon Marmor; Josep Masip; Marco Metra; Peter S Pang; Piotr Ponikowski; Rajnish Saini; Christoph Schumacher; Thomas M Severin
Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial.
Lancet 2013;381(9860):29-39.
2013: Holger Thiele; Uwe Zeymer; Karl Werdan
Intraaortic balloon support for cardiogenic shock.
The New England journal of medicine 2013;368(1):81.
2013: Daniel Tiller; Mathias Bruegel; Henning Ebelt; Karin Halina Greiser; Johannes Haerting; Alexander Kluttig; Jan A Kors; Sebastian Nuding; Martin Russ; Joachim Thiery; Karl Werdan
Prevalence of symptomatic heart failure with reduced and with normal ejection fraction in an elderly general population-the CARLA study.
PloS one 2013;8(3):e59225.
2013: S Dietz; H-P Hobbach; H Lemm; Karl Werdan; H Bushnaq; Michael Buerke
[Infective endocarditis : emergency treatment and long-term surveillance].
Der Internist 2013;54(1):51-62.
2013: Karl Werdan
[Acquired and congenital heart defects in adulthood : long-term care and special emergency situations].
Der Internist 2013;54(1):5-6.
2013: Joachim Wilhelm; Konstantin M Heinroth; Dietrich Stoevesandt; Karl Werdan; Alexander Plehn
Non-compaction cardiomyopathy with diffuse left coronary artery fistulae as a rare cause of congestive heart failure.
European heart journal 2013;34(1):12.
2012: Holger Thiele; Karl Werdan; Uwe Zeymer; Michael Böhm; Steffen Desch; Henning Ebelt; Ingo Eitel; Klaus Empen; Miroslaw Ferenc; Georg Fuernau; Jörg Fuhrmann; Rainer Hambrecht; Jörg Hausleiter; Marcus Hennersdorf; Franz-Josef Neumann; Hans-Georg Olbrich; Gert Richardt; Steffen Schneider; Gerhard Schuler
Intraaortic balloon support for myocardial infarction with cardiogenic shock.
The New England journal of medicine 2012;367(14):1287-96.
2012: J Wilhelm; M Amoury; A Christoph; Henning Ebelt; R Finke; D Hammer; S Hettwer; T Klöss; M Schürmann; Karl Werdan
Outcome prediction using clinical scores and biomarkers in patients with presumed severe infection in the emergency department.
Medizinische Klinik, Intensivmedizin und Notfallmedizin 2012;107(7):558-63.
2012: Roland Prondzinsky; Susanne Unverzagt; Karl Werdan; Michael Buerke; Justin M Carter; Dirk Mahnkopf; Konstantin M Heinroth
A novel approach for transcoronary pacing in a porcine model.
The Journal of invasive cardiology 2012;24(9):451-5.
2012: Roland Prondzinsky; J Thiery; S Unverzagt; N Wegener; Karl Werdan; Ute Buerke; M Fiedler; Johannes Haerting; Konstantin M Heinroth; H Lemm; Michael Buerke
Acute myocardial infarction and cardiogenic shock: prognostic impact of cytokines: INF-γ, TNF-α, MIP-1β, G-CSF, and MCP-1β.
Medizinische Klinik, Intensivmedizin und Notfallmedizin 2012;107(6):476-84.
2012: Susanne Schulz; Tim Seifert; Karl Werdan; Hans-Guenter Schaller; Axel Schlitt; Tanya Dudakliewa; Robert Gawe; Christiane Gläser; Britt Hofmann; Sandra Lischewski; Andrea Lutze; Stefan Reichert
The importance of genetic variants in TNFα for periodontal disease in a cohort of coronary patients.
Journal of clinical periodontology 2012;39(8):699-706.
2012: Rajesh Rawal; Alexander Teumer; Daniel Tiller; Henry Völzke; Henri Wallaschofski; Karl Werdan; Bjørn O Asvold; Henriette E Meyer zu Schwabedissen; Trine Bjøro; Angela Doering; Christian Gieger; Karin H Greiser; Thomas Illig; Till Ittermann; Christa Meisinger; Georg Homuth
Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function.
Human molecular genetics 2012;21(14):3275-82.
2012: Johannes Haerting; Alexander Kluttig; Sebastian Nuding; K H Greiser; Karl Werdan
[A cohort study investigating risk factors for cardiovascular disease in an urban elderly East-German population (CARLA study)].
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 2012;55(6-7):795-800.
2012: Holger Thiele; Karl Werdan; Michael Böhm; Rüdiger C Braun-Dullaeus; Suzanne de Waha; Steffen Desch; Henning Ebelt; Ingo Eitel; Klaus Empen; Hans-Reiner Figulla; Georg Fuernau; Rainer Hambrecht; Jörg Hausleiter; Marcus Hennersdorf; Volkhard Kurowski; Bernward Lauer; Sebastian K G Maier; Hans-Heinrich Minden; Helge Möllmann; Franz-Josef Neumann; Hans-Georg Olbrich; Kristin Rochor; Steffen Schneider; Gerhard Schuler; Bettina Schwarz; Ruth H Strasser; Uwe Zeymer
Intraaortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock: design and rationale of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial.
American heart journal 2012;163(6):938-45.
2012: Michael Buerke; Ute Buerke; Hasan Bushnaq; Sebastian Dietz; Henning Ebelt; Henning Lemm; Roland Prondzinsky; Rolf-Edgar Silber; Karl Werdan
Intra-aortic balloon counterpulsation in the treatment of infarction-related cardiogenic shock--review of the current evidence.
Artificial organs 2012;36(6):505-11.
2012: Karl Werdan; Michael Buerke; Georg Delle-Karth; Alexander Geppert; Martin Ruß; Friedrich A Schöndube
Cardiogenic shock due to myocardial infarction: diagnosis, monitoring and treatment: a German-Austrian S3 Guideline.
Deutsches Ärzteblatt international 2012;109(19):343-51.
2012: Karl Werdan
Do not get in RAGE in cardiogenic shock: it is detrimental!
Critical care medicine 2012;40(5):1669-70.
2012: Karl Werdan; Sebastian Nuding; Henning Ebelt; Guido Hack; Florian Höpfner; Ursula Müller-Werdan
Ivabradine in combination with beta-blocker improves symptoms and quality of life in patients with stable angina pectoris: results from the ADDITIONS study.
Clinical research in cardiology : official journal of the German Cardiac Society 2012;101(5):365-73.
2012: Roland Prondzinsky; Axel Schlitt; Joachim Thiery; Susanne Unverzagt; Nikolas-Arne Wegener; Karl Werdan; Ute Buerke; Sebastian Dietz; Martin G Fiedler; Konstantin M Heinroth; Patrick Kellner; Henning Lemm; Harald Loppnow; Michael Buerke
Interleukin-6, -7, -8 and -10 predict outcome in acute myocardial infarction complicated by cardiogenic shock.
Clinical research in cardiology : official journal of the German Cardiac Society 2012;101(5):375-84.
2012: Roland Prondzinsky; Uwe Raaz; Martin Russ; Axel Schlitt; Michael Swyter; Susanne Unverzagt; Nikolas Wegener; Karl Werdan; Ute Buerke; Henning Ebelt; Johannes Haerting; Konstantin M Heinroth; Henning Lemm; Michael Buerke
Hemodynamic effects of intra-aortic balloon counterpulsation in patients with acute myocardial infarction complicated by cardiogenic shock: the prospective, randomized IABP shock trial.
Shock (Augusta, Ga.) 2012;37(4):378-84.
2012: T Rahn; Karl Werdan; H Lemm; L Neumann; A Plehn; S Abromeit; F Busanny; S Dambeck; Henning Ebelt
[Shock, hemoconcentration, and generalized edema in a 47-year-old man].
Der Internist 2012;53(3):341-4.
2012: Robert S Hoke; Christine Lautenschläger; Ursula Müller-Werdan; Karl Werdan; Henning Ebelt
Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study.
Clinical research in cardiology : official journal of the German Cardiac Society 2012;101(2):139-47.
2012: Stefan Taudien; Karl Werdan; Andreas Wolf; Philip Rosenstiel; Gabor Gäbel; Karin Halina Greiser; Marco Groth; Robert Grützmann; Klaus Huse; Alexander Kluttig; Michael Krawczak; Oliver Kuss; Michael Nothnagel; Christian Pilarsky; Matthias Platzer
Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis.
BMC research notes 2012;5():629.
2012: Karl Werdan
The investigation of syncope: strengths and weaknesses of emergency medicine.
Deutsches Ärzteblatt international 2012;109(4):56-7.
2012: T Weber; Karl Werdan; H H Wolf; D Arnold; Maximilian Christopeit; T Ettrich; H J Holzhausen; A S Kekulé; A Lindner; C Lübbert; A Oehme; H J Schmoll; Henning Ebelt
[Unexplained fever and B-symptoms in a young male Black African].
Der Internist 2012;53(1):93-8.
2011: Karl Werdan
Secondary prevention following myocardial infarction--there is still more to be done.
Deutsches Ärzteblatt international 2011;108(50):854.
2011: Anja Kaeberich; Torsten Linde; Lars Maegdefessel; Elisabeth Perzborn; Uwe Raaz; Iris Reindl; Michael Buerke; Baerbel Hauroeder; Ulrich Steinseifer; Alexander Vogt; Karl Werdan; Axel Schlitt
Comparison of unfractionated heparin, low-molecular-weight heparin, low-dose and high-dose rivaroxaban in preventing thrombus formation on mechanical heart valves: results of an in vitro study.
Journal of thrombosis and thrombolysis 2011;32(4):417-25.
2011: Uwe Raaz; Rainer Rienmüller; Axel Schlitt; Rolf-Edgar Silber; Dietrich Stoevesandt; Philipp Thermann; Michael Buerke; Henning Ebelt; Ivar Friedrich; Ursula Müller-Werdan; Karl Werdan
Massive ascites generation following pacemaker infection: a case report.
Clinical research in cardiology : official journal of the German Cardiac Society 2011;100(10):945-9.
2011: Sebastian Nuding; Andreas Wienke; Henning Ebelt; Robert S Hoke; Annette Krummenerl; Ursula Müller-Werdan; Karl Werdan
Reducing elevated heart rate in patients with multiple organ dysfunction syndrome by the I (f) (funny channel current) inhibitor ivabradine : MODI (f)Y trial.
Clinical research in cardiology : official journal of the German Cardiac Society 2011;100(10):915-23.
2011: T J Ettrich; C Lübbert; H Ebelt; Karl Werdan
[Septic shock in a renal transplanted patient after consumption of uncooked pork meat].
Der Internist 2011;52(9):1114-7.
2011: Joachim Wilhelm; Curd Behrmann; Hassan Issa; Karl Werdan; Konstantin M Heinroth
Atypical course of a persistent left superior vena cava through the left atrium.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2011;12(8):635.
2011: Udo Klöckner; Harald Loppnow; Ursula Müller-Werdan; Uwe Rueckschloss; Karl Werdan; Henning Ebelt; Claudia Grossmann; Michael Gekle
Differential reduction of HCN channel activity by various types of lipopolysaccharide.
Journal of molecular and cellular cardiology 2011;51(2):226-35.
2011: Karl Werdan; Sebastian Bubel; Stefan Hettwer; Robert Hoke; Christine Lautenschläger; Ursula Mueller-Werdan; Sebastian Nuding; Anja Oelke; Martin Russ; Henning Ebelt
Septic cardiomyopathy: hemodynamic quantification, occurrence, and prognostic implications.
Clinical research in cardiology : official journal of the German Cardiac Society 2011;100(8):661-8.
2011: Iris Katharina Reind; Michael Buerke; Uwe Raaz; Alexander Vogt; Karl Werdan; Axel Schlitt
Detection of a left atrial thrombus under fondaparinux treatment: a case report.
Current drug safety 2011;6(3):201-3.
2011: Barbara Schumann; Andreas Seidler; Alexander Kluttig; Karl Werdan; Johannes Haerting; Karin Halina Greiser
Association of occupation with prevalent hypertension in an elderly East German population: an exploratory cross-sectional analysis.
International archives of occupational and environmental health 2011;84(4):361-9.
2011: Harald Loppnow; Li Zhang; Michael Buerke; Michael Lautenschläger; Li Chen; Adrian Frister; Axel Schlitt; Tanja Luther; Nan Song; Britt Hofmann; Stefan Rose-John; Rolf-Edgar Silber; Ursula Müller-Werdan; Karl Werdan
Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures.
Journal of cellular and molecular medicine 2011;15(4):994-1004.
2011: Michael Buerke; H Lemm; S Dietz; Karl Werdan
Pathophysiology, diagnosis, and treatment of infarction-related cardiogenic shock.
Herz 2011;36(2):73-83.
2011: Konstantin M Heinroth; Susanne Unverzagt; Michael Buerke; Justin Carter; Dirk Mahnkopf; Karl Werdan; Roland Prondzinsky
Transcoronary pacing in a porcine model--impact of guidewire insulation.
The Journal of invasive cardiology 2011;23(3):108-14.
2011: Harald Loppnow; Michael Buerke; Karl Werdan; Stefan Rose-John
Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis.
Journal of cellular and molecular medicine 2011;15(3):484-500.
2011: Ying Zhang; Katharina Köhler; Jia Xu; Di Lu; Thomas Braun; Axel Schlitt; Michael Buerke; Ursula Müller-Werdan; Karl Werdan; Henning Ebelt
Inhibition of p53 after acute myocardial infarction: reduction of apoptosis is counteracted by disturbed scar formation and cardiac rupture.
Journal of molecular and cellular cardiology 2011;50(3):471-8.
2011: Sebastian Schubert; Hansjörg Schwertz; Karl Werdan; Andrew S Weyrich; Zechariah G Franks; Stephan Lindemann; Harald Loppnow; Monika Otto; Peter Presek; Martin Russ; Axel Schlitt; Hagen Behr; Michael Buerke
Staphylococcus aureus α-toxin triggers the synthesis of B-cell lymphoma 3 by human platelets.
Toxins 2011;3(2):120-33.
2011: Doris Jäger; Karl Werdan; Ursula Müller-Werdan
Endogenous ADP-ribosylation of elongation factor-2 by interleukin-1β.
Molecular and cellular biochemistry 2011;348(1-2):125-8.
2011: Andreas Stang; Angela Döring; Henry Völzke; Susanne Moebus; Karin Halina Greiser; Karl Werdan; Klaus Berger; Ute Ellert; Hanne Neuhauser
Regional differences in body fat distributions among people with comparable body mass index: a comparison across six German population-based surveys.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2011;18(1):106-14.
2011: Susanne Unverzagt; Karl Werdan; Melchior Seyfarth; Alexander Solms; Holger Thiele; Michael Buerke; Daniel Burkhoff; Antoinette de Waha; Johannes Haerting; Maria-Theresia Machemer; E Magnus Ohman; Roland Prondzinsky
Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock.
Cochrane database of systematic reviews (Online) 2011;(7):CD007398.
2011: Barbara Schumann; Alexander Kluttig; Daniel Tiller; Karl Werdan; Johannes Haerting; Karin H Greiser
Association of childhood and adult socioeconomic indicators with cardiovascular risk factors and its modification by age: the CARLA Study 2002-2006.
BMC public health 2011;11():289.
2010: Alexey Surov; Rolf-Peter Spielmann; Karl Werdan; Michael Buerke; Curd Behrmann
A late presentation of giant traumatic pulmonary artery aneurysm.
Circulation 2010;122(24):2581-2.
2010: Ralf Koester; Jan Kaehler; Henning Ebelt; Gerold Soeffker; Karl Werdan; Thomas Meinertz
Ivabradine in combination with beta-blocker therapy for the treatment of stable angina pectoris in every day clinical practice.
Clinical research in cardiology : official journal of the German Cardiac Society 2010;99(10):665-72.
2010: Lars Maegdefessel; Torsten Linde; Franziska Krapiec; Kathrin Hamilton; Ulrich Steinseifer; Joanne van Ryn; Uwe Raaz; Michael Buerke; Karl Werdan; Axel Schlitt
In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves.
Thrombosis research 2010;126(3):e196-200.
2010: Buerkem Buerkem; H Lemm; K Krohe; S Dietz; U Raaz; Ute Buerke; M Russ; Axel Schlitt; Karl Werdan
Levosimendan in the treatment of cardiogenic shock.
Minerva cardioangiologica 2010;58(4):519-30.
2010: Michael Buerke; H Lemm; M Russ; Axel Schlitt; Karl Werdan
[Therapeutic strategies in acute decompensated heart failure and cardiogenic shock].
Der Internist 2010;51(8):963-74.
2010: Karl Werdan
[Internal medicine intensive care of cardiovascular emergencies].
Der Internist 2010;51(8):951-2.
2010: Frank M Brunkhorst; P Gastmeier; W Kern; W Krüger; Konstantin Mayer; A Weimann; T Welte; C Putensen; Karl Werdan; Konrad Reinhart
[Prevention and follow-up care of sepsis. 1st revision of S2k guidelines of the German Sepsis Society (Deutsche Sepsis-Gesellschaft e.V., DSG) and the German Interdisciplinary Association of Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin, DIVI)].
Der Internist 2010;51(7):925-32.
2010: H Ebelt; Karl Werdan
[Sepsis and heart].
Der Internist 2010;51(7):844-9.
2010: Henning Ebelt; Karl Werdan
[Intensive care medicine 2010].
Deutsche medizinische Wochenschrift (1946) 2010;135(25-26):1283-5.
2010: Hendrik Schmidt; Dirk Hoyer; Mathias Rauchhaus; Roland Prondzinsky; Ralf Hennen; Axel Schlitt; Justin Carter; Kuno Hottenrott; Ursula Müller-Werdan; Karl Werdan; Michael Buerke
ACE-inhibitor therapy and survival among patients with multiorgan dysfunction syndrome (MODS) of cardiac and non-cardiac origin.
International journal of cardiology 2010;140(3):296-303.
2010: Karl Werdan
Evaluation of medical emergency rooms.
Deutsches Ärzteblatt international 2010;107(15):259-60.
2010: Uwe Raaz; Michael Buerke; Marese Busshardt; Lars Maegdefessel; Alexander Plehn; Baerbel Hauroeder; Karl Werdan; Axel Schlitt
Efficacy of enoxaparin, certoparin and dalteparin in preventing cardiac catheter thrombosis: an in vitro approach.
Journal of thrombosis and thrombolysis 2010;29(3):265-70.
2010: Axel Schlitt; Bernhard Schwaab; Kirsten Fingscheidt; Karl J Lackner; Gunnar H Heine; Alexander Vogt; Michael Buerke; Lars Maegdefessel; Uwe Raaz; Karl Werdan; Xian-Cheng Jiang
Serum phospholipid transfer protein activity after a high fat meal in patients with insulin-treated type 2 diabetes.
Lipids 2010;45(2):129-35.
2010: Amalia Vaz Pérez; Katrin Otawa; Arabel V Zimmermann; Martin Stockburger; Ursula Müller-Werdan; Karl Werdan; Hendrik B Schmidt; Hüseyin Ince; Mathias Rauchhaus
The impact of impaired renal function on mortality in patients with acutely decompensated chronic heart failure.
European journal of heart failure 2010;12(2):122-8.
2010: Alexander Kluttig; Barbara Schumann; Cees A Swenne; Jan A Kors; Oliver Kuss; Hendrik Schmidt; Karl Werdan; Johannes Haerting; Karin H Greiser
Association of health behaviour with heart rate variability: a population-based study.
BMC cardiovascular disorders 2010;10():58.
2010: Konrad Reinhart; Frank M Brunkhorst; H-G Bone; J Bardutzky; C-E Dempfle; H Forst; P Gastmeier; Herwig Gerlach; M Gründling; S John; W Kern; G Kreymann; W Krüger; P Kujath; G Marggraf; J Martin; Konstantin Mayer; Andreas Meier-Hellmann; M Oppert; C Putensen; Michael Quintel; Maximilian Ragaller; Rolf Rossaint; H Seifert; C Spies; F Stüber; Norbert Weiler; A Weimann; Karl Werdan; T Welte
Prevention, diagnosis, therapy and follow-up care of sepsis: 1st revision of S-2k guidelines of the German Sepsis Society (Deutsche Sepsis-Gesellschaft e.V. (DSG)) and the German Interdisciplinary Association of Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin (DIVI)).
German medical science : GMS e-journal 2010;8():Doc14.
2010: Roland Prondzinsky; Henning Lemm; Michael Swyter; Nikolas Wegener; Susanne Unverzagt; Justin M Carter; Martin Russ; Axel Schlitt; Ute Buerke; Arnd Christoph; Hendrik Schmidt; Matthias Winkler; Joachim Thiery; Karl Werdan; Michael Buerke
Intra-aortic balloon counterpulsation in patients with acute myocardial infarction complicated by cardiogenic shock: the prospective, randomized IABP SHOCK Trial for attenuation of multiorgan dysfunction syndrome.
Critical care medicine 2010;38(1):152-60.
2009: Konstantin M Heinroth; Justin M Carter; Michael Buerke; Dirk Mahnkopf; Karl Werdan; Roland Prondzinsky
Optimizing of transcoronary pacing in a porcine model.
The Journal of invasive cardiology 2009;21(12):634-8.
2009: Martin Russ; Roland Prondzinsky; Justin M Carter; Axel Schlitt; Henning Ebelt; Hendrik Schmidt; Henning Lemm; Konstantin Heinroth; Gerold Soeffker; Matthias Winkler; Karl Werdan; Michael Buerke
Right ventricular function in myocardial infarction complicated by cardiogenic shock: Improvement with levosimendan.
Critical care medicine 2009;37(12):3017-23.
2009: Alexey Surov; Andreas Wienke; Justin M Carter; Dietrich Stoevesandt; Curd Behrmann; Rolf-Peter Spielmann; Karl Werdan; Michael Buerke
Intravascular embolization of venous catheter--causes, clinical signs, and management: a systematic review.
JPEN. Journal of parenteral and enteral nutrition 2009;33(6):677-85.
2009: Jason N Katz; Amanda L Stebbins; John H Alexander; Harmony R Reynolds; Karen S Pieper; Witold Ruzyllo; Karl Werdan; Alexander Geppert; Vladimir Dzavik; Frans Van de Werf; Judith S Hochman
Predictors of 30-day mortality in patients with refractory cardiogenic shock following acute myocardial infarction despite a patent infarct artery.
American heart journal 2009;158(4):680-7.
2009: Ursula Müller-Werdan; J Wilhelm; S Hettwer; Sebastian Nuding; Henning Ebelt; Karl Werdan
[Specific aspects in septic patients: initial phase in the emergency department, age, sex and post-ICU-care].
Der Internist 2009;50(7):828, 830-2, 834-6, passim.
2009: Karl Werdan; S Hettwer; S Bubel; A Oelke; R S Hoke; R Wimmer; Henning Ebelt; Ursula Müller-Werdan
[Septic circulatory shock and septic cardiomyopathy].
Der Internist 2009;50(7):799-800, 802-6, 808-9.
2009: Lars Maegdefessel; Torsten Linde; Thomas Michel; Kathrin Hamilton; Ulrich Steinseifer; Ivar Friedrich; Sebastian Schubert; Baerbel Hauroeder; Uwe Raaz; Michael Buerke; Karl Werdan; Axel Schlitt
Argatroban and bivalirudin compared to unfractionated heparin in preventing thrombus formation on mechanical heart valves. Results of an in-vitro study.
Thrombosis and haemostasis 2009;101(6):1163-9.
2009: Uwe Raaz; Lars Maegdefessel; Michael Buerke; Matthias Janusch; Karl Werdan; Axel Schlitt
INR matters: a case on managing argatroban for bridging oral anticoagulation in a patient with heparin induced thrombocytopenia type II after mechanical heart valve replacement.
Thrombosis research 2009;124(2):242-3.
2009: Martin Russ; Karl Werdan; Jochen Cremer; Arno Krian; Thomas Meinertz; Hans-Reinhard Zerkowski
Different treatment options in chronic coronary artery disease: when is it the time for medical treatment, percutaneous coronary intervention or aortocoronary bypass surgery?
Deutsches Ärzteblatt international 2009;106(15):253-61.
2009: Karl Werdan; Hendrik Schmidt; Henning Ebelt; Klaus Zorn-Pauly; Bernd Koidl; Robert Sebastian Hoke; Konstantin Heinroth; Ursula Müller-Werdan
Impaired regulation of cardiac function in sepsis, SIRS, and MODS.
Canadian journal of physiology and pharmacology 2009;87(4):266-74.
2009: Robert Sebastian Hoke; Konstantin Heinroth; Hans-Joachim Trappe; Karl Werdan
Is external defibrillation an electric threat for bystanders?
Resuscitation 2009;80(4):395-401.
2009: Li Chen; Adrian Frister; Song Wang; Andreas Ludwig; Hagen Behr; Susanna Pippig; Beibei Li; Andreas Simm; Britt Hofmann; Claudia Pilowski; Susanne Koch; Michael Buerke; Stefan Rose-John; Karl Werdan; Harald Loppnow
Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production.
American journal of physiology. Heart and circulatory physiology 2009;296(4):H987-96.
2009: Axel Schlitt; Stefan Blankenberg; Christoph Bickel; Karl J Lackner; Gunnar H Heine; Michael Buerke; Karl Werdan; Lars Maegdefessel; Uwe Raaz; Hans J Rupprecht; Thomas Munzel; Xian-Cheng Jiang
PLTP activity is a risk factor for subsequent cardiovascular events in CAD patients under statin therapy: the AtheroGene study.
Journal of lipid research 2009;50(4):723-9.
2009: Karin Halina Greiser; Alexander Kluttig; Barbara Schumann; Cees A Swenne; Jan A Kors; Oliver Kuss; Johannes Haerting; Hendrik Schmidt; Joachim Thiery; Karl Werdan
Cardiovascular diseases, risk factors and short-term heart rate variability in an elderly general population: the CARLA study 2002-2006.
European journal of epidemiology 2009;24(3):123-42.
2009: Karl Werdan
Intra-aortic balloon counterpulsation in septic shock--really?
Critical care medicine 2009;37(1):325-6.
2008: R Hennen; I Friedrich; D Hoyer; S Nuding; Mathias Rauchhaus; M Schulze; S Schlisske; R Schwesig; A Schlitt; Michael Buerke; Ursula Müller-Werdan; Karl Werdan; H Schmidt
[Autonomic dysfunction and beta-adrenergic blockers in multiple organ dysfunction syndrome].
Deutsche medizinische Wochenschrift (1946) 2008;133(48):2500-4.
2008: Henning Ebelt; Ying Zhang; Alexander Kampke; Jia Xu; Axel Schlitt; Michael Buerke; Ursula Müller-Werdan; Karl Werdan; Nanette Kälin
E2F2 expression induces proliferation of terminally differentiated cardiomyocytes in vivo.
Cardiovascular research 2008;80(2):219-26.
2008: Sarah Seiler; Axel Schlitt; Xian-Cheng Jiang; Christof Ulrich; Stefan Blankenberg; Karl J Lackner; Matthias Girndt; Karl Werdan; Michael Buerke; Danilo Fliser; Gunnar H Heine
Cholesteryl ester transfer protein activity and cardiovascular events in patients with chronic kidney disease stage V.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(11):3599-604.
2008: Lars Maegdefessel; Michael Buerke; Sebastian Schubert; Iris Reindl; Thomas Michel; Baerbel Hauroeder; Justin M Carter; Dirk Peetz; Karl Werdan; Axel Schlitt
Comparison of bivalirudin, enoxaparin, and unfractionated heparin in preventing cardiac catheter thrombosis. Results of an in-vitro study.
Thrombosis and haemostasis 2008;100(4):693-8.
2008: Lars Maegdefessel; Axel Schlitt; Julie Faerber; Shannan Pearl Bond; Claudia-Martina Messow; Michael Buerke; Uwe Raaz; Karl Werdan; Thomas Muenzel; Christian Weiss
Anticoagulant and/or antiplatelet treatment in patients with atrial fibrillation after percutaneous coronary intervention. A single-center experience.
Medizinische Klinik (Munich, Germany : 1983) 2008;103(9):628-32.
2008: Henning Ebelt; Ying Zhang; Katharina Köhler; Jia Xu; Praveen Gajawada; Thomas Boettger; Thomas Hollemann; Ursula Müller-Werdan; Karl Werdan; Nanette Kälin
Directed expression of dominant-negative p73 enables proliferation of cardiomyocytes in mice.
Journal of molecular and cellular cardiology 2008;45(3):411-9.
2008: Hansjörg Schwertz; Justin M Carter; Martin Russ; Sebastian Schubert; Axel Schlitt; Ute Buerke; Martin Schmidt; Heinz Hillen; Karl Werdan; Michael Buerke
Serine protease inhibitor nafamostat given before reperfusion reduces inflammatory myocardial injury by complement and neutrophil inhibition.
Journal of cardiovascular pharmacology 2008;52(2):151-60.
2008: M Winkler; Karl Werdan
[Intensive care medicine 2008].
Deutsche medizinische Wochenschrift (1946) 2008;133(25-26):1356-61.
2008: Hendrik Schmidt; Ursula Müller-Werdan; Karl Werdan
Assessment of vagal activity during transcutaneous vagus nerve stimulation in mice.
Critical care medicine 2008;36(6):1990.
2008: Axel Schlitt; Hans J Rupprecht; Iris Reindl; Sebastian Schubert; Baerbel Hauroeder; Justin M Carter; Dirk Peetz; Stefan S Kropff; Lars Maegdefessel; Martin Russ; Hendrik Schmidt; Henning Ebelt; Karl Werdan; Michael Buerke
In-vitro comparison of fondaparinux, unfractionated heparin, and enoxaparin in preventing cardiac catheter-associated thrombus.
Coronary artery disease 2008;19(4):279-84.
2008: Kambiz Norozi; Reiner Buchhorn; Armin Wessel; Jens Bahlmann; Björn Raab; Siegfried Geyer; Titus Kuehne; Li Beibei; Karl Werdan; Harald Loppnow
Beta-blockade does not alter plasma cytokine concentrations and ventricular function in young adults with right ventricular dysfunction secondary to operated congenital heart disease.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(5):747-52.
2008: Harald Loppnow; Karl Werdan; Michael Buerke
Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms.
Innate immunity 2008;14(2):63-87.
2008: Ute Buerke; Justin M Carter; Axel Schlitt; Martin Russ; Hendrik Schmidt; Ulf Sibelius; Ulrich Grandel; Friedrich Grimminger; Werner Seeger; Ursula Mueller-Werdan; Karl Werdan; Michael Buerke
Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy.
Shock (Augusta, Ga.) 2008;29(4):497-503.
2008: Ute Buerke; Diethard Pruefer; J M Carter; Martin Russ; Axel Schlitt; R Prondzinsky; J Makowski; S Rohrbach; B Niemann; C Schulze; M Dahm; C-F Vahl; Karl Werdan; Michael Buerke
Sodium/hydrogen exchange inhibition with cariporide reduces leukocyte adhesion via P-selectin suppression during inflammation.
British journal of pharmacology 2008;153(8):1678-85.
2008: Hendrik Schmidt; Dirk Hoyer; Ralf Hennen; Konstantin Heinroth; Mathias Rauchhaus; Roland Prondzinsky; Kuno Hottenrott; Michael Buerke; Ursula Müller-Werdan; Karl Werdan
Autonomic dysfunction predicts both 1- and 2-month mortality in middle-aged patients with multiple organ dysfunction syndrome.
Critical care medicine 2008;36(3):967-70.
2008: Karl Werdan; Günter Pilz; Ursula Müller-Werdan; Monika Maas Enriquez; Dierk V Schmitt; Friedrich-Wilhelm Mohr; Gertraud Neeser; Friedrich Schöndube; Hans-Joachim Schäfers; Axel Haverich; Peter Fraunberger; Jan Andersson; Eckart Kreuzer; Lambert G Thijs
Immunoglobulin G treatment of postcardiac surgery patients with score-identified severe systemic inflammatory response syndrome--the ESSICS study.
Critical care medicine 2008;36(3):716-23.
2008: Hendrik Schmidt; Dirk Hoyer; Joachim Wilhelm; Gerold Söffker; Konstantin M Heinroth; Kuno Hottenrott; Samir M Said; Michael Buerke; Ursula Müller-Werdan; Karl Werdan
The alteration of autonomic function in multiple organ dysfunction syndrome.
Critical care clinics 2008;24(1):149-63, ix.
2008: Elena Westphal; Susanne Rohrbach; Michael Buerke; Hagen Behr; Dorothea Darmer; Rolf-Edgar Silber; Karl Werdan; Harald Loppnow
Altered interleukin-1 receptor antagonist and interleukin-18 mRNA expression in myocardial tissues of patients with dilatated cardiomyopathy.
Molecular medicine (Cambridge, Mass.) 2008;14(1-2):55-63.
2008: Arnd Christoph; Roland Prondzinsky; Martin Russ; Matthias Janusch; Axel Schlitt; Henning Lemm; Sebastian Reith; Karl Werdan; Michael Buerke
Early and sustained haemodynamic improvement with levosimendan compared to intraaortic balloon counterpulsation (IABP) in cardiogenic shock complicating acute myocardial infarction.
Acute cardiac care 2008;10(1):49-57.
2007: Klaus Zorn-Pauly; Brigitte Pelzmann; Petra Lang; Heinrich Mächler; Hendrik Schmidt; Henning Ebelt; Karl Werdan; Bernd Koidl; Ursula Müller-Werdan
Endotoxin impairs the human pacemaker current If.
Shock (Augusta, Ga.) 2007;28(6):655-661.
2007: Karl Werdan; Günter Pilz; Oskar Bujdoso; Peter Fraunberger; Gertraud Neeser; Roland Erich Schmieder; Burkhard Viell; Walter Marget; Margret Seewald; Peter Walger; Ralph Stuttmann; Norbert Speichermann; Claus Peckelsen; Volkhard Kurowski; Hans-Heinrich Osterhues; Ljiljana Verner; Roswita Neumann; Ursula Müller-Werdan
Score-based immunoglobulin G therapy of patients with sepsis: the SBITS study.
Critical care medicine 2007;35(12):2693-2701.
2007: Hansjörg Schwertz; Justin M Carter; Mulati Abdudureheman; Martin Russ; Ute Buerke; Axel Schlitt; Ursula Müller-Werdan; Roland Prondzinsky; Karl Werdan; Michael Buerke
Myocardial ischemia/reperfusion causes VDAC phosphorylation which is reduced by cardioprotection with a p38 MAP kinase inhibitor.
Proteomics 2007;7(24):4579-88.
2007: Karl Werdan
Mirror, mirror on the wall, which is the fairest meta-analysis of all?
Critical care medicine 2007;35(12):2852-4.
2007: Michael Buerke; M Russ; Karl Werdan
[New pharmacological treatment approaches to cardiogenic shock].
Der Internist 2007;48(12):1442-9.
2007: Martin Russ; Roland Prondzinsky; Arnd Christoph; Axel Schlitt; Ute Buerke; Gerold Söffker; Henning Lemm; Michael Swyter; Nikolas Wegener; Matthias Winkler; Justin M Carter; Sebastian Reith; Karl Werdan; Michael Buerke
Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shock.
Critical care medicine 2007;35(12):2732-9.
2007: S Hettwer; B Panzner-Grote; Rochus Witthaut; Karl Werdan
Isolated diastolic dysfunction--diagnostic value of tissue Doppler imaging, colour M-mode and N-terminal pro B-type natriuretic peptide.
Clinical research in cardiology : official journal of the German Cardiac Society 2007;96(12):874-82.
2007: Susanne Rohrbach; Stefan Engelhardt; Martin J Lohse; Karl Werdan; Juergen Holtz; Ursula Muller-Werdan
Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6.
Molecular medicine (Cambridge, Mass.) 2007;13(11-12):605-14.
2007: Ursula Müller-Werdan; M Meisel; P Schirdewahn; Karl Werdan
[Elderly patients with cardiovascular diseases].
Der Internist 2007;48(11):1211-9.
2007: Michael Buerke; Diethard Pruefer; Dennis Sankat; Justin M Carter; Ute Buerke; Martin Russ; Axel Schlitt; Ivar Friedrich; Jochen Börgermann; Christian F Vahl; Karl Werdan
Effects of aprotinin on gene expression and protein synthesis after ischemia and reperfusion in rats.
Circulation 2007;116(11 Suppl):I121-6.
2007: H Ebelt; Karl Werdan
[Emergency therapy for acute heart failure].
Der Internist 2007;48(9):938-47.
2007: Konstantin M Heinroth; Marcel Elster; Sebastian Nuding; Frithjof Schlegel; Arnd Christoph; Justin Carter; Michael Buerke; Karl Werdan
Impedance cardiography: a useful and reliable tool in optimization of cardiac resynchronization devices.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2007;9(9):744-50.
2007: Karl Werdan
[Intensive care medicine 2007].
Deutsche medizinische Wochenschrift (1946) 2007;132(25-26):1383-7.
2007: D Stoevesandt; Michael Buerke; Curd Behrmann; Konstantin M Heinroth; Rolf P Spielmann; Karl Werdan; Axel Schlitt
Detection of a persistent left superior vena cava by echocardiography, computed tomography, and magnetic resonance imaging.
Clinical research in cardiology : official journal of the German Cardiac Society 2007;96(3):191-2.
2007: Hendrik Schmidt; Jana Saworski; Karl Werdan; Ursula Müller-Werdan
Decreased beating rate variability of spontaneously contracting cardiomyocytes after co-incubation with endotoxin.
Journal of endotoxin research 2007;13(6):339-42.
2007: Elena Westphal; Claudia Pilowski; Susanne Koch; Henning Ebelt; Ursula Müller-Werdan; Karl Werdan; Harald Loppnow
Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1alpha.
Journal of endotoxin research 2007;13(1):25-34.
2007: Axel Schlitt; Gunnar H Heine; Xian-Cheng Jiang; Martina Messow; Stefan Blankenberg; Hans J Rupprecht; Christof Ulrich; Michael Buerke; Karl Werdan; Karl J Lackner; Hans Köhler; Matthias Girndt
Phospholipid transfer protein in hemodialysis patients.
American journal of nephrology 2007;27(2):138-43.
2007: Henning Ebelt; Mirco Jungblut; Ying Zhang; Thomas Kubin; Sawa Kostin; Antje Technau; Svetlana Oustanina; Sylvia Niebrügge; Jürgen Lehmann; Karl Werdan; Nanette Kälin
Cellular cardiomyoplasty: improvement of left ventricular function correlates with the release of cardioactive cytokines.
Stem cells (Dayton, Ohio) 2007;25(1):236-44.
2007: Michael Buerke; Markus Guckenbiehl; Hansjörg Schwertz; Ute Buerke; Michael Hilker; Herbert Platsch; Joachim Richert; Sabine Bomm; Guy A Zimmerman; Stephan Lindemann; Ursula Mueller-Werdan; Karl Werdan; Harald Darius; Andrew S Weyrich
Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury.
Biochimica et biophysica acta 2007;1774(1):5-15.
2006: Uwe Janssens; Karl Werdan
[Required monitoring in the intensive care unit].
Herz 2006;31(8):749-60.
2006: Henning Ebelt; Zhipei Liu; Ursula Müller-Werdan; Karl Werdan; Nanette Kälin
Making omelets without breaking eggs: E2F-mediated induction of cardiomyoycte cell proliferation without stimulation of apoptosis.
Cell cycle (Georgetown, Tex.) 2006;5(21):2436-9.
2006: Hendrik Schmidt; Ursula Müller-Werdan; Thomas Hoffmann; Darrel P Francis; Massimo F Piepoli; Mathias Rauchhaus; Roland Prondzinsky; Harald Loppnow; Michael Buerke; Dirk Hoyer; Karl Werdan
Attenuated autonomic function in multiple organ dysfunction syndrome across three age groups.
Biomedizinische Technik. Biomedical engineering 2006;51(4):264-7.
2006: Michael Buerke; Hansjörg Schwertz; Tina Längin; Ute Buerke; Roland Prondzinsky; Herbert Platsch; Joachim Richert; Sabine Bomm; Martin Schmidt; Heinz Hillen; Stephan Lindemann; Gottfried Blaschke; Ursula Müller-Werdan; Karl Werdan
Proteome analysis of myocardial tissue following ischemia and reperfusion--effects of complement inhibition.
Biochimica et biophysica acta 2006;1764(10):1536-45.
2006: Susanne Schulz; Undraga Schagdarsurengin; Dirk Rehfeld; Thomas Süss; Karl Werdan; Ursula Müller-Werdan; Christiane Gläser
Genetic impact of TNF-beta on risk factors for coronary atherosclerosis.
European cytokine network 2006;17(3):148-54.
2006: Karl Werdan
Disseminated intravascular coagulation: a matter for immune globulins in sepsis?
Critical care medicine 2006;34(9):2505-6.
2006: K Reinhart; Frank M Brunkhorst; H-G Bone; Herwig Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; Konstantin Mayer; A Meier-Hellmann; C Peckelsen; C Putensen; F Stüber; M Quintel; Maximilian Ragaller; R Rossaint; Norbert Weiler; T Welte; Karl Werdan
[Diagnosis and therapy of sepsis].
Clinical research in cardiology : official journal of the German Cardiac Society 2006;95(8):429-54.
2006: Hendrik Schmidt; Ralf Hennen; Alexander Keller; Martin Russ; Ursula Müller-Werdan; Karl Werdan; Michael Buerke
Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome.
Intensive care medicine 2006;32(8):1248-51.
2006: Dirk Hoyer; Birgit Frank; Bernd Pompe; Hendrik Schmidt; Karl Werdan; Ursula Müller-Werdan; Rafal Baranowski; Jan Zebrowski; Winfried Meissner; Ulf Kletzin; Daniela Adler; Steffen Adler; Reinhard Blickhan
Analysis of complex physiological systems by information flow: a time scale-specific complexity assessment.
Biomedizinische Technik. Biomedical engineering 2006;51(2):41-8.
2006: Frank M Brunkhorst; Karl Werdan
[Intensive care medicine: after positive studies questions occur].
Deutsche medizinische Wochenschrift (1946) 2006;131(25-26):1441-4.
2006: Konrad Reinhart; Frank M Brunkhorst; H Bone; Herwig Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; Konstantin Mayer; Andreas Meier-Hellmann; C Peckelsen; C Putensen; Michael Quintel; Maximilian Ragaller; Rolf Rossaint; F Stüber; Norbert Weiler; T Welte; Karl Werdan
[Diagnosis and therapy of sepsis: guidelines of the German Sepsis Society Inc. and the German Interdisciplinary Society for Intensive and Emergency Medicine].
Der Anaesthesist 2006;55 Suppl 1():43-56.
2006: Karl Werdan
Immunoglobulin treatment in sepsis--is the answer "no"?
Critical care medicine 2006;34(5):1542-4.
2006: Dirk Hoyer; Holger Friedrich; Ulrich Zwiener; Bernd Pompe; Rafal Baranowski; Karl Werdan; Ursula Müller-Werdan; Hendrik Schmidt
Prognostic impact of autonomic information flow in multiple organ dysfunction syndrome patients.
International journal of cardiology 2006;108(3):359-69.
2006: Konstantin M Heinroth; Ina Stabenow; Ines Moldenhauer; Susanne Unverzagt; Michael Buerke; Karl Werdan; Roland Prondzinsky
Temporary trans-coronary pacing by coated guidewires: a safe and reliable method during percutaneous coronary intervention.
Clinical research in cardiology : official journal of the German Cardiac Society 2006;95(4):206-11.
2006: Axel Schlitt; Diethard Pruefer; Ute Buerke; Martin Russ; Manfred Dahm; Hellmut Oelert; Karl Werdan; Michael Buerke
Neutrophil adherence to activated saphenous vein and mammary endothelium after graft preparation.
The Annals of thoracic surgery 2006;81(4):1262-8.
2006: Konrad Reinhart; Frank M Brunkhorst; H Bone; Herwig Gerlach; M Gründling; G Kreymann; P Kujath; G Marggraf; Konstantin Mayer; Andreas Meier-Hellmann; C Peckelsen; C Putensen; Michael Quintel; Maximilian Ragaller; Rolf Rossaint; F Stüber; Norbert Weiler; T Welte; Karl Werdan
[Diagnosis and therapy of sepsis. Guidelines of the German Sepsis Society Inc. and the German Interdisciplinary Society for Intensive and Emergency Medicine].
Der Internist 2006;47(4):356, 358-60, 362-8, passim.
2006: Karl Werdan
[Future perspectives of cardiovascular intensive care medicine].
Medizinische Klinik (Munich, Germany : 1983) 2006;101 Suppl 1():80-3.
2006: Elena Westphal; Mona Herzberg; Ingo Neumann; Li Beibei; Claudia Pilowski; Chen Li; Karl Werdan; Harald Loppnow
Neutrophils process interleukin-1beta and interleukin-18 precursors in a caspase-1-like fashion--processing is inhibited by human vascular smooth muscle cells.
European cytokine network 2006;17(1):19-28.
2006: Ursula Muller-Werdan; Martin Russ; Frithjof Schlegel; Axel Schlitt; Hendrik B Schmidt; Gerold Söffker; Michael Buerke; Henning Ebelt; Konstantin M Heinroth; Anja Herklotz; Harald Loppnow; Karl Werdan
Septic cardiomyopathy - A not yet discovered cardiomyopathy?
Experimental and clinical cardiology 2006;11(3):226-36.
2006: Axel Schlitt; Stefan Blankenberg; Daoguang Yan; Hans Von Gizycki; Michael Buerke; Karl Werdan; Christoph Bickel; Karl J Lackner; Juergen Meyer; Hans J Rupprecht; Xian-Cheng Jiang
Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease.
Nutrition & metabolism 2006;3():5.
2005: Hendrik Schmidt; Ursula Müller-Werdan; Thomas Hoffmann; Darrel P Francis; Massimo F Piepoli; Mathias Rauchhaus; Roland Prondzinsky; Harald Loppnow; Michael Buerke; Dirk Hoyer; Karl Werdan
Autonomic dysfunction predicts mortality in patients with multiple organ dysfunction syndrome of different age groups.
Critical care medicine 2005;33(9):1994-2002.
2005: Simon Cohen; Charles Sprung; Peter Sjokvist; Anne Lippert; Bara Ricou; Mario Baras; Seppo Hovilehto; Paulo Maia; Dermot Phelan; Konrad Reinhart; Karl Werdan; Hans-Henrik Bulow; Tom Woodcock
Communication of end-of-life decisions in European intensive care units.
Intensive care medicine 2005;31(9):1215-21.
2005: Susanne Schulz; Katrin Köhler; Undraga Schagdarsurengin; Petra Greiser; Gerd Birkenmeier; Ursula Müller-Werdan; Karl Werdan; Christiane Gläser
The human FGF2 level is influenced by genetic predisposition.
International journal of cardiology 2005;101(2):265-71.
2005: U Mathony; Hendrik Schmidt; C Gröger; Darrel P Francis; I Konzag; Ursula Müller-Werdan; Karl Werdan; Joachim Syska
Optimal maximum tracking rate of dual-chamber pacemakers required by children and young adults for a maximal cardiorespiratory performance.
Pacing and clinical electrophysiology : PACE 2005;28(5):378-83.
2005: Roland Prondzinsky; Axel Knüpfer; Harald Loppnow; Frank Redling; Dirk W Lehmann; Ina Stabenow; Rochus Witthaut; Susanne Unverzagt; Joachim Radke; Hans Zerkowski; Karl Werdan
Surgical trauma affects the proinflammatory status after cardiac surgery to a higher degree than cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 2005;129(4):760-6.
2005: H Schmidt; R R Flieger; R Hennen; P Tymiec; M Winkler; D Hoyer; Michael Buerke; Ursula Müller-Werdan; Karl Werdan
[Reversible autonomic dysfunction in a young woman with septic multiple organ dysfunction syndrome].
Deutsche medizinische Wochenschrift (1946) 2005;130(12):648-51.
2005: Henning Ebelt; Nadine Hufnagel; Petra Neuhaus; Herbert Neuhaus; Praveen Gajawada; Andreas Simm; Ursula Müller-Werdan; Karl Werdan; Nanette Kälin
Divergent siblings: E2F2 and E2F4 but not E2F1 and E2F3 induce DNA synthesis in cardiomyocytes without activation of apoptosis.
Circulation research 2005;96(5):509-17.
2005: S Reith; Karl Werdan
[Therapy of organ failure in primary extracardiac diseases].
Der Internist 2005;46(3):256-64.
2005: Hansjörg Schwertz; Roland Prondzinsky; Hans-Stefan Hofmann; Rolf-Edgar Silber; Karl Werdan; Michael Buerke
Transesophageal echocardiographic image of a thrombus crossing a persistent foramen ovale from the right into the left atrium.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2005;18(3):278-9.
2005: Susanne Rohrbach; Ursula Muller-Werdan; Karl Werdan; Susanne Koch; Norbert F Gellerich; Juergen Holtz
Apoptosis-modulating interaction of the neuregulin/erbB pathway with anthracyclines in regulating Bcl-xS and Bcl-xL in cardiomyocytes.
Journal of molecular and cellular cardiology 2005;38(3):485-93.
2005: Corinne Alberti; Christian Brun-Buisson; Sylvie Chevret; Massimo Antonelli; Sergey V Goodman; Claudio Martin; Rui Moreno; Ana R Ochagavia; Mark Palazzo; Karl Werdan; Jean-Roger Le Gall
Systemic inflammatory response and progression to severe sepsis in critically ill infected patients.
American journal of respiratory and critical care medicine 2005;171(5):461-8.
2005: Hendrik Schmidt; Darrel P Francis; Mathias Rauchhaus; Karl Werdan; Massimo F Piepoli
Chemo- and ergoreflexes in health, disease and ageing.
International journal of cardiology 2005;98(3):369-78.
2005: Karin H Greiser; Alexander Kluttig; Barbara Schumann; Jan A Kors; Cees A Swenne; Oliver Kuss; Karl Werdan; Johannes Haerting
Cardiovascular disease, risk factors and heart rate variability in the elderly general population: design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study.
BMC cardiovascular disorders 2005;5():33.
2004: Sebastian Reith; Karl Werdan
[Intensive care medicine 2004].
Medizinische Klinik (Munich, Germany : 1983) 2004;99(10):603-12.
2004: Hansjörg Schwertz; Ursula Müller-Werdan; Roland Prondzinsky; Karl Werdan; Michael Buerke
[Catecholamine therapy in cardiogenic shock: helpful, useless or dangerous?].
Deutsche medizinische Wochenschrift (1946) 2004;129(37):1925-30.
2004: Susanne Schulz; Undraga Schagdarsurengin; Thomas Suss; Ursula Müller-Werdan; Karl Werdan; Christiane Gläser
Relation between the tumor necrosis factor-alpha (TNF-alpha) gene and protein expression, and clinical, biochemical, and genetic markers: age, body mass index and uric acid are independent predictors for an elevated TNF-alpha plasma level in a complex risk model.
European cytokine network 2004;15(2):105-11.
2004: Hendrik Schmidt; Ursula Müller-Werdan; Sebastian Nuding; Thomas Hoffmann; Darrel P Francis; Dirk Hoyer; Mathias Rauchhaus; Karl Werdan
Impaired chemoreflex sensitivity in adult patients with multiple organ dysfunction syndrome--the potential role of disease severity.
Intensive care medicine 2004;30(4):665-72.
2004: Roland Prondzinsky; Karl Werdan; Michael Buerke
[Cardiogenic shock: pathophysiology, clinics, therapeutical options and perspectives].
Der Internist 2004;45(3):284-95.
2004: Karl Werdan
[Arteriosclerosis and coronary heart disease--a hundred years later].
Zeitschrift für ärztliche Fortbildung und Qualitätssicherung 2004;98(1):66-9.
2003: Ursula Müller-Werdan; Michael Buerke; Karl Werdan
[Progress in therapy of infection].
Der Internist 2003;44(12):1531-40.
2003: Susanne Schulz; Gerd Birkenmeier; Undraga Schagdarsurengin; Katrin Wenzel; Ursula Müller-Werdan; Dirk Rehfeld; Thomas Süss; Andrea Kabisch; Karl Werdan; Christiane Gläser
Role of LDL receptor-related protein (LRP) in coronary atherosclerosis.
International journal of cardiology 2003;92(2-3):137-44.
2003: Rochus Witthaut; Christian Busch; Peter Fraunberger; Autar Walli; Dietrich Seidel; Günter Pilz; Ralph Stuttmann; Norbert Speichermann; Ljifane Verner; Karl Werdan
Plasma atrial natriuretic peptide and brain natriuretic peptide are increased in septic shock: impact of interleukin-6 and sepsis-associated left ventricular dysfunction.
Intensive care medicine 2003;29(10):1696-702.
2003: Ursula Müller-Werdan; Karl Werdan
[End-organ damage in inflammation and sepsis].
Der Internist 2003;44(7):864-71.
2002: Susanne Schulz; Undraga Schagdarsurengin; Petra Greiser; Gerd Birkenmeier; Ursula Müller-Werdan; Monika Hagemann; Dagmar Riemann; Karl Werdan; Christiane Gläser
The LDL receptor-related protein (LRP1/A2MR) and coronary atherosclerosis--novel genomic variants and functional consequences.
Human mutation 2002;20(5):404.
2002: Claudia Werner; Harald Loppnow; Mathias Rauchhaus; Armin Wessel; Karl Werdan; Reiner Buchhorn
Cytokines in chronic heart failure: possible interaction in the neurohormonal and the cytokine system at the cAMP level?
European cytokine network 2002;13(4):407-9.
2002: Onnen Moerer; Alexandra Schmid; Michael Hofmann; Anja Herklotz; Konrad Reinhart; Karl Werdan; Heinz Schneider; Hilmar Burchardi
Direct costs of severe sepsis in three German intensive care units based on retrospective electronic patient record analysis of resource use.
Intensive care medicine 2002;28(10):1440-6.
2002: Doris Jäger; Jürgen Holtz; Nicholas T Redpath; Sylvana P Müller; Klaus Pönicke; Ingrid Heinroth-Hoffmann; Karl Werdan; Ursula Müller-Werdan
The ageing heart: influence of cellular and tissue ageing on total content and distribution of the variants of elongation factor-2.
Mechanisms of ageing and development 2002;123(10):1305-19.
2002: Harald Loppnow; Karl Werdan; Claudia Werner
The enhanced plasma levels of soluble tumor necrosis factor receptors (sTNF-R1; sTNF-R2) and interleukin-10 (IL-10) in patients suffering from chronic heart failure are reversed in patients treated with beta-adrenoceptor antagonist.
Autonomic & autacoid pharmacology 2002;22(2):83-92.
2002: H Schmidt; T Hoffmann; Karl Werdan
[Autonomic dysfunction in heart patients].
Der Internist 2002;43 Suppl 1():S76-83.
2002: Karl Werdan
[Can decubitus ulcer always be prevented?].
Der Internist 2002;43(3):414-5.
2002: Frank N Gellerich; Sonata Trumbeckaite; Jens Rüdiger Opalka; Johannes Frank Gellerich; Ying Chen; Christiane Neuhof; Heinz Redl; Karl Werdan; Stephan Zierz
Mitochondrial dysfunction in sepsis: evidence from bacteraemic baboons and endotoxaemic rabbits.
Bioscience reports 2002;22(1):99-113.
2002: Doris Jäger; Ursula Müller-Werdan; Klaus Pönicke; Jürgen Holtz; Karl Werdan; Sylvana P Müller
The impact of insulin-like growth factor-1 on the pattern of cardiac elongation factor-2 variants in a model of overload.
Molecular and cellular biochemistry 2002;229(1-2):25-34.
2001: Reiner Buchhorn; Armin Wessel; Martin Hulpke-Wette; JH Bürsch; Karl Werdan; Harald Loppnow
Endogenous nitric oxide and soluble tumor necrosis factor receptor levels are enhanced in infants with congenital heart disease.
Critical care medicine 2001;29(11):2208-10.
2001: H B Schmidt; Mathias Rauchhaus; Darrel P Francis; C L Davies; Sebastian Nuding; T Peschel; D S Schmidt; Andrew J S Coats; H Opitz; Karl Werdan
Assessment of chemoreflex sensitivity in free breathing young subjects by correction for respiratory influence.
International journal of cardiology 2001;78(2):157-65.
2001: G Soeffker; H B Schmidt; N G Rainov; Karl Werdan
[Refractory angina pectoris in end-stage coronary disease; relief through neuromodulation?].
Der Internist 2001;42(4):571-9.
2001: Harald Loppnow; Elena Westphal; Reiner Buchhorn; A Wessel; Karl Werdan
Interleukin-1 and related proteins in cardiovascular disease in adults and children.
Shock (Augusta, Ga.) 2001;16 Suppl 1():3-9.
2000: Konstantin M Heinroth; Karl Werdan
[Temporary pacemaker therapy. Transvenous, transcutaneous or transgastric?].
Der Internist 2000;41(10):1019-26, 1028-30.
2000: D Jäger; C Seliger; N T Redpath; I Friedrich; R E Silber; Klaus Pönicke; Karl Werdan; Ursula Müller-Werdan
Heterogeneity of cardiac rat and human elongation factor 2.
Electrophoresis 2000;21(13):2729-36.
2000: U Müller-Werdan; Karl Werdan
Immune modulation by catecholamines--a potential mechanism of cytokine release in heart failure?
Herz 2000;25(3):271-3.
2000: U Müller-Werdan; Karl Werdan
[Anaphylaxis and allergy. Recommendations for emergency treatment].
Der Internist 2000;41(4):363-73.
2000: U Müller-Werdan; Karl Werdan
[Anaphylactic shock].
Wiener klinische Wochenschrift 2000;112(4):149-56.
2000: M Krivokuca; Karl Werdan
[Therapy of acute heart failure. Emergency therapy].
Der Internist 2000;41(2 Pt 1):127-36.
2000: Elena Westphal; Ivar Friedrich; Rolf-Edgar Silber; Karl Werdan; Harald Loppnow
Processing of interleukin-18 by human vascular smooth muscle cells.
Advances in experimental medicine and biology 2000;477():343-8.
2000: C Kuhn; Ursula Müller-Werdan; D V Schmitt; H Lange; Günter Pilz; Eckart Kreuzer; Friedrich-Wilhelm Mohr; Hans Zerkowski; Karl Werdan
Improved outcome of APACHE II score-defined escalating systemic inflammatory response syndrome in patients post cardiac surgery in 1996 compared to 1988-1990: the ESSICS-study pilot project.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2000;17(1):30-7.
1999: Johannes N Hoffmann; Karl Werdan; Wolfgang H Hartl; Marianne Jochum; Eugen Faist; Dietrich Inthorn
Hemofiltrate from patients with severe sepsis and depressed left ventricular contractility contains cardiotoxic compounds.
Shock (Augusta, Ga.) 1999;12(3):174-80.
1999: Frank N Gellerich; Sonata Trumbeckaite; Kathrin Hertel; Stephan Zierz; Ursula Müller-Werdan; Karl Werdan; Heinz Redl; G Schlag
Impaired energy metabolism in hearts of septic baboons: diminished activities of Complex I and Complex II of the mitochondrial respiratory chain.
Shock (Augusta, Ga.) 1999;11(5):336-41.
1999: Peter Fraunberger; S Schaefer; Karl Werdan; Autar K Walli; Dietrich Seidel
Reduction of circulating cholesterol and apolipoprotein levels during sepsis.
Clinical chemistry and laboratory medicine : CCLM / FESCC 1999;37(3):357-62.
1999: Karl Werdan
The overall concept: immunoglobulins as adjuvants for mediastinitis--does it make sense?
The European journal of surgery. Supplement. : = Acta chirurgica. Supplement 1999;(584):33-8.
1998: Ursula Müller-Werdan; H Engelmann; Karl Werdan
Cardiodepression by tumor necrosis factor-alpha.
European cytokine network 1998;9(4):689-91.
1998: Harald Loppnow; Karl Werdan; G Reuter; Hans-Dieter Flad
The interleukin-1 and interleukin-1 converting enzyme families in the cardiovascular system.
European cytokine network 1998;9(4):675-80.
1998: Peter Fraunberger; Günter Pilz; P Cremer; Karl Werdan; Autar K Walli
Association of serum tumor necrosis factor levels with decrease of cholesterol during septic shock.
Shock (Augusta, Ga.) 1998;10(5):359-63.
1998: Günter Pilz; Karl Werdan
[Scores for multiple organ dysfunction and multiple organ failure].
Der Internist 1998;39(5):502-8.
1998: Rochus Witthaut; Karl Werdan; H P Schuster
[Multiple organ dysfunction syndrome and multiple organ failure. Diagnosis, prognosis and therapeutic concepts].
Der Internist 1998;39(5):493-501.
1998: Ursula Müller-Werdan; H Schumann; Harald Loppnow; RALPH FUCHS; Dorothea Darmer; J Stadler; Juergen Holtz; Karl Werdan
Endotoxin and tumor necrosis factor alpha exert a similar proinflammatory effect in neonatal rat cardiomyocytes, but have different cardiodepressant profiles.
Journal of molecular and cellular cardiology 1998;30(5):1027-36.
1998: F Redling; Roland Prondzinsky; Rochus Witthaut; Peter Fraunberger; Karl Werdan; Hans Zerkowski
[Significance of the heart-lung machine for the concept of minimal invasive heart surgery].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115():1516-9.
1998: Harald Loppnow; R Bil; S Hirt; Uwe Schönbeck; Mona Herzberg; Karl Werdan; Ernst Th Rietschel; Ernst Brandt; Hans-Dieter Flad
Platelet-derived interleukin-1 induces cytokine production, but not proliferation of human vascular smooth muscle cells.
Blood 1998;91(1):134-41.
1997: R Zell; P Geck; Karl Werdan; P Boekstegers
TNF-alpha and IL-1 alpha inhibit both pyruvate dehydrogenase activity and mitochondrial function in cardiomyocytes: evidence for primary impairment of mitochondrial function.
Molecular and cellular biochemistry 1997;177(1-2):61-7.
1997: Ursula Müller-Werdan; H Schumann; RALPH FUCHS; C Reithmann; Harald Loppnow; S Koch; U Zimny-Arndt; C He; Dorothea Darmer; Peter Jungblut; J Stadler; Juergen Holtz; Karl Werdan
Tumor necrosis factor alpha (TNF alpha) is cardiodepressant in pathophysiologically relevant concentrations without inducing inducible nitric oxide-(NO)-synthase (iNOS) or triggering serious cytotoxicity.
Journal of molecular and cellular cardiology 1997;29(11):2915-23.
1997: Karl Werdan
[Cytokines and heart diseases. Attempt at an update].
Medizinische Klinik (Munich, Germany : 1983) 1997;92(7):432-8.
1997: Roland Prondzinsky; Ursula Müller-Werdan; Günter Pilz; Rochus Witthaut; Ina Stabenow; Karl Werdan; Hans Zerkowski
[Systemic inflammatory reactions to extracorporeal therapy measures (II): Cardiopulmonary bypass].
Wiener klinische Wochenschrift 1997;109(10):346-53.
1997: Ursula Müller-Werdan; A Pfeifer; G Hübner; C Seliger; C Reithmann; H Rupp; Karl Werdan
Partial inhibition of protein synthesis by Pseudomonas exotoxin A deranges catecholamine sensitivity of cultured rat heart myocytes.
Journal of molecular and cellular cardiology 1997;29(2):799-811.
1997: Günter Pilz; R Appel; Eckart Kreuzer; Karl Werdan
Comparison of early IgM-enriched immunoglobulin vs polyvalent IgG administration in score-identified postcardiac surgical patients at high risk for sepsis.
Chest 1997;111(2):419-26.
1997: Georges von Degenfeld; W Peter; Helmut Habazettl; M von Lüdinghausen; Karl Werdan; Peter Boekstegers
Relationship between regional myocardial oxygenation and function during acute ischemia supported by selective suction and retroinfusion (SSR) in pigs.
Advances in experimental medicine and biology 1997;428():243-51.
1997: Ursula Müller-Werdan; Roland Prondzinsky; Rochus Witthaut; N Stache; Konstantin M Heinroth; C Kuhn; H Schmidt; I Busch; Karl Werdan
[The heart in infection and MODS (multiple organ dysfunction syndrome)].
Wiener klinische Wochenschrift 1997;109 Suppl 1():3-24.
1996: Rochus Witthaut; Karl Werdan
[Outcomes research exemplified by infection].
Der Internist 1996;37(12):1249-59.
1996: Karl Werdan; Ursula Müller-Werdan
Elucidating molecular mechanisms of septic cardiomyopathy--the cardiomyocyte model.
Molecular and cellular biochemistry 1996;163-164():291-303.
1996: Christoph Salat; Peter Boekstegers; Ernst Holler; Karl Werdan; B Reinhardt; S Fateh-Moghadam; Rudolf Pihusch; M Kaul; Thomas Beinert; Erhard Hiller
Hemostatic parameters in sepsis patients treated with anti-TNF alpha-monoclonal antibodies.
Shock (Augusta, Ga.) 1996;6(4):233-7.
1996: Christopher Reithmann; Wolfgang von Scheidt; Karl Werdan
Beta-adrenoceptor desensitization despite cardiac denervation in human failing transplanted myocardium.
International journal of cardiology 1996;56(1):11-5.
1996: U Müller-Werdan; B Koidl; A Autenrieth; D Klein; Karl Werdan; C Hammer
Xenoreactive natural antibodies and induced antibodies--their effects of beating cardiomyocytes as a model of a xenograft.
Molecular and cellular biochemistry 1996;160-161():315-23.
1996: Christopher Reithmann; C Scheininger; T Bulgan; Karl Werdan
Exposure to the n-3 polyunsaturated fatty acid docosahexaenoic acid impairs alpha 1-adrenoceptor-mediated contractile responses and inositol phosphate formation in rat cardiomyocytes.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(2):109-19.
1996: A Autenrieth; U Müller-Werdan; B Koidl; Karl Werdan; C Hammer
Different action of xenoreactive natural and immune antibodies on functioning cardiomyocytes.
Transplantation proceedings 1996;28(2):576-7.
1996: Günter Pilz; Peter Fraunberger; R Appel; Eckart Kreuzer; Karl Werdan; Autar K Walli; Dietrich Seidel
Early prediction of outcome in score-identified, postcardiac surgical patients at high risk for sepsis, using soluble tumor necrosis factor receptor-p55 concentrations.
Critical care medicine 1996;24(4):596-600.
1996: Peter Boekstegers; I Kainz; Wolfgang Giehrl; W Peter; Karl Werdan
Subchronic exposure of cardiomyocytes to low concentrations of tumor necrosis factor alpha attenuates the positive inotropic response not only to catecholamines but also to cardiac glycosides and high calcium concentrations.
Molecular and cellular biochemistry 1996;156(2):135-43.
1995: Claus Vogelmeier; U Müller-Werdan; Karl Werdan
[Circulatory shock. Extrapulmonary etiology of respiratory insufficiency].
Der Internist 1995;36(8):756-64.
1995: Gerhard Bauriedel; Martin Schwaiblmair; Eckart Kreuzer; Karl Werdan
[Intra-aortic balloon counterpulsation as percutaneous therapy option in cardiogenic shock].
Deutsche medizinische Wochenschrift (1946) 1995;120(23):834-8.
1995: U Müller-Werdan; B Koidl; A Autenrieth; D Klein; M Zander; Karl Werdan; C Hammer
Preformed natural antibodies: their impact on contractile activity of cardiomyocytes.
Transplantation proceedings 1995;27(3):2109-11.
1995: RM Arendt; Michael Schmoeckel; Ute Wilbert-Lampen; L Heucke; Karl Werdan
Neurohumoral regulation of endothelin release by opioid and natriuretic peptides.
Transplantation proceedings 1995;27(3):2092-6.
1995: Gerhard Bauriedel; Martin Schwaiblmair; M Näbauer; A Heuck; H Hertlein; Iris Bittmann; A Nerlich; Karl Werdan
[Spontaneous hemothorax in dermatomyositis and long-term glucocorticoid treatment].
Deutsche medizinische Wochenschrift (1946) 1995;120(7):209-13.
1995: RM Arendt; Michael Schmoeckel; Ute Wilbert-Lampen; A Plasse; L Heucke; Karl Werdan
Bidirectional effects of endogenous opioid peptides on endothelin release rates in porcine aortic endothelial cell culture: mediation by delta opioid receptor and opioid receptor antagonist-insensitive mechanisms.
The Journal of pharmacology and experimental therapeutics 1995;272(1):1-7.
1995: Christopher Reithmann; Karl Werdan
Chronic muscarinic cholinoceptor stimulation increases adenylyl cyclase responsiveness in rat cardiomyocytes by a decrease in the level of inhibitory G-protein alpha-subunits.
Naunyn-Schmiedeberg's archives of pharmacology 1995;351(1):27-34.
1994: U Müller-Werdan; D Klein; M Zander; Karl Werdan; C Hammer
Beating neonatal rat cardiomyocytes as a model to study the role of xenoreactive natural antibodies in xenotransplantation.
Transplantation 1994;58(12):1403-9.
1994: U Müller; D Klein; M Zander; Karl Werdan; C Hammer
Preformed natural antibodies: their impact on beating neonatal rat cardiomyocytes.
Transplantation proceedings 1994;26(2):1000-2.
1994: Peter Boekstegers; S Weidenhöfer; T Kapsner; Karl Werdan
Skeletal muscle partial pressure of oxygen in patients with sepsis.
Critical care medicine 1994;22(4):640-50.
1994: Günter Pilz; P McGinn; Peter Boekstegers; S Kääb; S Weidenhöfer; Karl Werdan
Pseudomonas sepsis does not cause more severe cardiovascular dysfunction in patients than non-Pseudomonas sepsis.
Circulatory shock 1994;42(4):174-82.
1994: Peter Boekstegers; S Weidenhöfer; Roland Zell; Ernst Holler; T Kapsner; H Redl; Günther Schlag; M Kaul; J Kempeni; Karl Werdan
Changes in skeletal muscle pO2 after administration of anti-TNF alpha-antibody in patients with severe sepsis: comparison to interleukin-6 serum levels, APACHE II, and Elebute scores.
Shock (Augusta, Ga.) 1994;1(4):246-53.
1994: Günter Pilz; P McGinn; Karl Werdan
Evaluation of definitions of sepsis.
Chest 1994;105(3):970-1.
1994: Peter Boekstegers; W Peter; Georges von Degenfeld; Christoph A Nienaber; M Abend; T C Rehders; Helmut Habazettl; T Kapsner; M von Lüdinghausen; Karl Werdan
Preservation of regional myocardial function and myocardial oxygen tension during acute ischemia in pigs: comparison of selective synchronized suction and retroinfusion of coronary veins to synchronized coronary venous retroperfusion.
Journal of the American College of Cardiology 1994;23(2):459-69.
1994: Christopher Reithmann; Karl Werdan
Tumor necrosis factor alpha decreases inositol phosphate formation and phosphatidylinositol-bisphosphate (PIP2) synthesis in rat cardiomyocytes.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(2):175-82.
1994: Günter Pilz; Eckart Kreuzer; S Kääb; R Appel; Karl Werdan
Early sepsis treatment with immunoglobulins after cardiac surgery in score-identified high-risk patients.
Chest 1994;105(1):76-82.
1994: Günter Pilz; S Kääb; Eckart Kreuzer; Karl Werdan
Evaluation of definitions and parameters for sepsis assessment in patients after cardiac surgery.
Infection 1994;22(1):8-17.
1993: Christopher Reithmann; S Hallström; Günter Pilz; T Kapsner; Günther Schlag; Karl Werdan
Desensitization of rat cardiomyocyte adenylyl cyclase stimulation by plasma of noradrenaline-treated patients with septic shock.
Circulatory shock 1993;41(1):48-59.
1993: Günter Pilz; S Kääb; Eckart Kreuzer; Karl Werdan
[Early detection of patients at risk for infection after heart surgery].
Infusionstherapie und Transfusionsmedizin 1993;20 Suppl 1():6-14; discussion 15.
1993: Günter Pilz; Eckart Kreuzer; S Kääb; R Appel; Karl Werdan
[Early immunoglobulin therapy in high risk patients for infection after heart surgery].
Infusionstherapie und Transfusionsmedizin 1993;20 Suppl 1():35-40; discussion 41.
1993: Peter Boekstegers; S Weidenhöfer; T Kapsner; Karl Werdan
[Continuous measurement of peripheral oxygen availability in skeletal muscle of patients with infection].
Infusionstherapie und Transfusionsmedizin 1993;20 Suppl 1():21-8; discussion 28.
1992: Christopher Reithmann; B Panzner; Karl Werdan
Distinct pathways for beta-adrenoceptor-induced up-regulation of muscarinic acetylcholine receptors and inhibitory G-protein alpha-subunits in chicken cardiomyocytes.
Naunyn-Schmiedeberg's archives of pharmacology 1992;345(5):530-40.
1992: C Hammer; C Csapo; G Höbel; U Müller; Karl Werdan
Preformed natural antibodies: action on endothelial cells.
Transplantation proceedings 1992;24(2):590-1.
1992: Peter Boekstegers; A Pfeifer; W Peter; Karl Werdan
Contractile dysfunction of "reperfused" neonatal rat heart cells: a model for studying "myocardial stunning" at the cellular level?
Advances in experimental medicine and biology 1992;317():573-82.
1991: Christopher Reithmann; P Gierschik; Karl Werdan; K H Jakobs
Role of inhibitory G protein alpha-subunits in adenylyl cyclase desensitization.
Molecular and cellular endocrinology 1991;82(2-3):C215-21.
1991: Karl Werdan
[Therapy of mitral valve prolapse syndrome when there are contraindications to beta-blockers].
Der Internist 1991;32(11):660-1.
1991: Karl Werdan; Peter Boekstegers; U Müller; A Pfeifer; Günter Pilz; Christopher Reithmann; S Hallström; B Koidl; H P Schuster; Günther Schlag
[Acute septic cardiomyopathy: a manifestation in multi-organ failure in infection?].
Medizinische Klinik (Munich, Germany : 1983) 1991;86(10):526-34.
1991: Peter Boekstegers; S Weidenhöfer; Günter Pilz; Karl Werdan
Peripheral oxygen availability within skeletal muscle in sepsis and septic shock: comparison to limited infection and cardiogenic shock.
Infection 1991;19(5):317-23.
1991: Karl Werdan; U Müller; Christopher Reithmann; A Pfeifer; S Hallström; B Koidl; Günther Schlag
Mechanisms in acute septic cardiomyopathy: evidence from isolated myocytes.
Basic research in cardiology 1991;86(5):411-21.
1991: Günter Pilz; S Kääb; G Neeser; I Class; U Schweigart; A Brähler; O Bujdoso; R Neumann; Karl Werdan
Supplemental immunoglobulin (ivIgG) treatment in 163 patients with sepsis and septic shock--an observational study as a prerequisite for placebo-controlled clinical trials.
Infection 1991;19(4):216-27.
1991: Karl Werdan
[Beta receptor blockers in acute myocardial infarct and in secondary prevention].
Der Internist 1991;32(6):359-60.
1991: Günter Pilz; T Gurniak; O Bujdoso; Karl Werdan
A basic program for calculation of APACHE II and Elebute scores and sepsis evaluation in intensive care medicine.
Computers in biology and medicine 1991;21(3):143-59.
1991: Günter Pilz; S Kääb; O Bujdoso; R Neumann; Karl Werdan
[Supplemental infection therapy with i.v. immunoglobulins (polyvalent IgG and Pseudomonas IgG)--results of an observational case study with 163 patients].
Klinische Wochenschrift 1991;69 Suppl 26():178-84.
1991: Günter Pilz; I Class; Peter Boekstegers; A Pfeifer; U Müller; Karl Werdan
Pseudomonas immunoglobulin therapy in patients with Pseudomonas sepsis and septic shock.
Antibiotics and chemotherapy 1991;44():120-35.
1990: Christopher Reithmann; Karl Werdan
[Regulation of beta receptors--practical consequences for therapy].
Der Internist 1990;31(10):625-31.
1990: Günter Pilz; Karl Werdan
Cardiovascular parameters and scoring systems in the evaluation of response to therapy in sepsis and septic shock.
Infection 1990;18(5):253-62.
1989: Karl Werdan; U Müller
[Mitral valve prolapse and mitral valve prolapse syndrome].
Der Internist 1989;30(8):475-82.
1989: Karl Werdan; S Melnitzki; Günter Pilz; E Reuschel-Janetschek
[Use of pseudomonas immunoglobulin. Indications and results].
Anästhesie, Intensivtherapie, Notfallmedizin 1989;24(3):153-61.
1989: Günter Pilz; Karl Werdan
[Score systems in intensive care medicine].
Der Internist 1989;30(2):82-7.
1989: Günter Pilz; A Stäblein; E Reuschel-Janetschek; G Autenrieth; Karl Werdan
The use of scoring systems in patients with cardiogenic and septic shock.
Progress in clinical and biological research 1989;308():625-31.
1989: Karl Werdan; Günter Pilz; S Kääb
Haemodynamic effects during treatment of sepsis and septic shock with immunoglobulins and plasma-pheresis.
Progress in clinical and biological research 1989;308():1025-30.
1989: Karl Werdan; S M Melnitzki; Günter Pilz; T Kapsner
The cultured rat heart cell: a model to study direct cardiotoxic effects of pseudomonas endo- and exotoxins.
Progress in clinical and biological research 1989;308():247-51.
1988: Karl Werdan; E Kreuzer; G Autenrieth
[Respiratory failure with cough attacks and angina pectoris during a walk through the woods].
Der Internist 1988;29(10):710-3.
1988: X Baur; A Bortsch; G Autenrieth; K Jacob; J Neudert; B Schneider; Karl Werdan
[Carcinoid syndrome with a course of more than 10 years].
Der Internist 1988;29(5):347-50.
1988: D Beuckelmann; N Pritzl; R Rienmüller; Karl Werdan
[A 35-year-old patient with polyarthritis and a stenosing colon tumor].
Der Internist 1988;29(4):285-8.
1988: H J Berger; Karl Werdan; Erland Erdmann
Regulation of cardiac glycoside receptors with different affinities for cardiac glycosides in cultured rat heart cells.
Progress in clinical and biological research 1988;268B():345-52.