FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jon Wergedal

Research Profile

Living Beings

Concepts & Ideas

Anatomy

Chemicals & Drugs

Physiology

Genes & Molecular Sequences

Quantitative Trait Loci

Procedures

Chromosome Mapping

Co-author Network

Publications

TOP 3
Ha-Young Kim; Sheila Pourteymour; Jon E Wergedal; Catrina Alarcon; Subburaman Mohan
Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice.
Chandra Deb; Bo Li; Subburaman Mohan; David J Baylink; Michael Chen; Jon E Wergedal; Weirong Xing; Wenyi Zhang; Xuezhong Qin
Transgenic overexpression of pregnancy-associated plasma protein-A in skeletal muscle of mice increases myofiber size and central nucleation in sedentary muscle and promotes muscle regeneration in the injured muscle.
Hongrun Yu; Yongliang Zhao; Jon E Wergedal; Subburaman Mohan
Targeted disruption of TGFBI in mice reveals its role in regulating bone mass and bone size through periosteal bone formation.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jon Wergedal (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Ha-Young Kim; Sheila Pourteymour; Jon E Wergedal; Catrina Alarcon; Subburaman Mohan
Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice.
American journal of physiology. Endocrinology and metabolism 2013;304(5):E531-7.
2012: Chandra Deb; Bo Li; Subburaman Mohan; David J Baylink; Michael Chen; Jon E Wergedal; Weirong Xing; Wenyi Zhang; Xuezhong Qin
Transgenic overexpression of pregnancy-associated plasma protein-A in skeletal muscle of mice increases myofiber size and central nucleation in sedentary muscle and promotes muscle regeneration in the injured muscle.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2012;22(5):173-9.
2012: Hongrun Yu; Yongliang Zhao; Jon E Wergedal; Subburaman Mohan
Targeted disruption of TGFBI in mice reveals its role in regulating bone mass and bone size through periosteal bone formation.
Calcified tissue international 2012;91(1):81-7.
2012: Gabriel R Linares; David R Powell; Jon E Wergedal; Weirong Xing; Fatima Z Alshbool; Robert Brommage; Shin-Tai Chen; K-H William Lau; Subburaman Mohan
Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(7):1553-65.
2012: Hongrun Yu; Patrick J Johnson; Chandrasekhar Kesavan; Heather Watt; Jon E Wergedal; Subburaman Mohan
Lasting consequences of traumatic events on behavioral and skeletal parameters in a mouse model for post-traumatic stress disorder (PTSD).
PloS one 2012;7(8):e42684.
2012: Matilda H-C Sheng; Jon E Wergedal; Mehran Amoui; David J Baylink; Subburaman Mohan; K-H William Lau
Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice.
PloS one 2012;7(4):e35280.
2011: Chandrasekhar Kesavan; K-H William Lau; Jon E Wergedal; Subburaman Mohan
Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading.
American journal of physiology. Endocrinology and metabolism 2011;301(6):E1191-7.
2011: Michael J Coen; Charles H Rundle; Jon E Wergedal; Shin-Tai Chen; K-H William Lau
Lentiviral-based BMP4 in vivo gene transfer strategy increases pull-out tensile strength without an improvement in the osteointegration of the tendon graft in a rat model of biceps tenodesis.
The journal of gene medicine 2011;13(10):511-21.
2011: Susan L Hall; Shin-Tai Chen; Jon E Wergedal; Daila S Gridley; Subburaman Mohan; K-H William Lau
Stem cell antigen-1 positive cell-based systemic human growth hormone gene transfer strategy increases endosteal bone resorption and bone loss in mice.
The journal of gene medicine 2011;13(2):77-88.
2010: David Phang; Mark Rehage; Blake Bonafede; Diana Hou; Weirong Xing; Subburaman Mohan; Jon E Wergedal; Xuezhong Qin
Inactivation of insulin-like-growth factors diminished the anabolic effects of pregnancy-associated plasma protein-A (PAPP-A) on bone in mice.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2010;20(3):192-200.
2009: K-H William Lau; Reinhard Gysin; Shin-Tai Chen; Jon E Wergedal; David J Baylink; Subburaman Mohan
Marrow stromal cell-based cyclooxygenase 2 ex vivo gene-transfer strategy surprisingly lacks bone-regeneration effects and suppresses the bone-regeneration action of bone morphogenetic protein 4 in a mouse critical-sized calvarial defect model.
Calcified tissue international 2009;85(4):356-67.
2009: Allison Cox; Cheryl L Ackert-Bicknell; Beth L Dumont; Yueming Ding; Jordana Tzenova Bell; Gudrun A Brockmann; Jon E Wergedal; Carol Bult; Beverly Paigen; Jonathan Flint; Shirng-Wern Tsaih; Gary Churchill; Karl W Broman
A new standard genetic map for the laboratory mouse.
Genetics 2009;182(4):1335-44.
2009: Matilda H-C Sheng; Mehran Amoui; Virginia Stiffel; Apurva K Srivastava; Jon E Wergedal; K-H William Lau
Targeted transgenic expression of an osteoclastic transmembrane protein-tyrosine phosphatase in cells of osteoclastic lineage increases bone resorption and bone loss in male young adult mice.
The Journal of biological chemistry 2009;284(17):11531-45.
2009: Hongrun Yu; BOUCHRA EDDERKAOUI; Alejandro Cortez; Heather M Davidson; Jon E Wergedal; David J Baylink; Subburaman Mohan
Mapping of the chromosome 17 BMD QTL in the F(2) male mice of MRL/MpJ x SJL/J.
Genetica 2009;135(1):59-66.
2008: Kristen E Govoni; Jon E Wergedal; Robert B Chadwick; Apurva K Srivastava; Subburaman Mohan
Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice.
American journal of physiology. Endocrinology and metabolism 2008;295(5):E1172-80.
2008: Charles H Rundle; Xiaoguang Wang; Matilda H-C Sheng; Jon E Wergedal; K-H William Lau; Subburaman Mohan
Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis.
Bone 2008;43(5):880-8.
2008: Charles H Rundle; Xiaoguang Wang; Jon E Wergedal; Subburaman Mohan; K-H William Lau
Fracture healing in mice deficient in plasminogen activator inhibitor-1.
Calcified tissue international 2008;83(4):276-84.
2008: Cassandra A Strohbach; Charles H Rundle; Jon E Wergedal; Shin-Tai Chen; Thomas A Linkhart; K-H William Lau; Donna Strong
LMP-1 retroviral gene therapy influences osteoblast differentiation and fracture repair: a preliminary study.
Calcified tissue international 2008;83(3):202-11.
2008: Matilda H-C Sheng; Jon E Wergedal; Subburaman Mohan; K-H William Lau
Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.
FEBS letters 2008;582(10):1451-8.
2008: Charles H Rundle; Donna Strong; Shin-Tai Chen; Thomas A Linkhart; Matilda H-C Sheng; Jon E Wergedal; K-H William Lau; David J Baylink
Retroviral-based gene therapy with cyclooxygenase-2 promotes the union of bony callus tissues and accelerates fracture healing in the rat.
The journal of gene medicine 2008;10(3):229-41.
2007: Mark Rehage; Subburaman Mohan; Jon E Wergedal; Blake Bonafede; Kiet Tran; Diana Hou; David Phang; Ashok Kumar; Xuezhong Qin
Transgenic overexpression of pregnancy-associated plasma protein-A increases the somatic growth and skeletal muscle mass in mice.
Endocrinology 2007;148(12):6176-85.
2007: Kristen Govoni; Jon E Wergedal; Lore Florin; Peter Angel; David J Baylink; Subburaman Mohan
Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion.
Endocrinology 2007;148(12):5706-15.
2007: S Mohan; V Chest; R B Chadwick; Jon E Wergedal; A K Srivastava
Chemical mutagenesis induced two high bone density mouse mutants map to a concordant distal chromosome 4 locus.
Bone 2007;41(5):860-8.
2007: Susan L Hall; K-H William Lau; Shin-Tai Chen; Jon E Wergedal; Apurva Srivastava; Henry J Klamut; Matilda H-C Sheng; Daila S Gridley; Subburaman Mohan; David J Baylink
Sca-1(+) hematopoietic cell-based gene therapy with a modified FGF-2 increased endosteal/trabecular bone formation in mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(10):1881-9.
2007: BOUCHRA EDDERKAOUI; David J Baylink; Wesley G Beamer; Kathryn L Shultz; Jon E Wergedal; Subburaman Mohan
Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice.
Bone 2007;41(3):340-5.
2007: Kristen Govoni; Seong Keun Lee; Yoon-Sok Chung; Richard R Behringer; Jon E Wergedal; David J Baylink; Subburaman Mohan
Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.
Physiological genomics 2007;30(3):354-62.
2007: Jon E Wergedal; Cheryl L Ackert-Bicknell; Wesley G Beamer; Subburaman Mohan; David J Baylink; Apurva K Srivastava
Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains.
Journal of lipid research 2007;48(8):1724-34.
2007: Xiaoguang Wang; Charles H Rundle; Jon E Wergedal; Apurva K Srivastava; Subburaman Mohan; K-H William Lau
Loss of sex-specific difference in femoral bone parameters in male leptin knockout mice.
Calcified tissue international 2007;80(6):374-82.
2007: Charu Dogra; Harish Changotra; Nia Wedhas; Xuezhong Qin; Jon E Wergedal; Ashok Kumar
TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1857-69.
2007: BOUCHRA EDDERKAOUI; David J Baylink; Wesley G Beamer; Jon E Wergedal; Ryan Porte; Asok Chaudhuri; Subburaman Mohan
Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene.
Genome research 2007;17(5):577-85.
2007: Robert B Chadwick; Liming Bu; Hongrun Yu; Yan Hu; Jon E Wergedal; Subburaman Mohan; David J Baylink
Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2007;15(2):275-84.
2007: Hongrun Yu; Subburaman Mohan; BOUCHRA EDDERKAOUI; Godfred L Masinde; H M Davidson; Jon E Wergedal; Wesley G Beamer; David J Baylink
Detecting novel bone density and bone size quantitative trait loci using a cross of MRL/MpJ and CAST/EiJ inbred mice.
Calcified tissue international 2007;80(2):103-10.
2006: Xuezhong Qin; Jon E Wergedal; Mark Rehage; Kiet Tran; Jacqueline Newton; Paggie Lam; David J Baylink; Subburaman Mohan
Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivo.
Endocrinology 2006;147(12):5653-61.
2006: Charu Dogra; Harish Changotra; Jon E Wergedal; Ashok Kumar
Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch.
Journal of cellular physiology 2006;208(3):575-85.
2006: Chandrasekhar Kesavan; Subburaman Mohan; Apurva K Srivastava; Susanna Kapoor; Jon E Wergedal; Hongrun Yu; David J Baylink
Identification of genetic loci that regulate bone adaptive response to mechanical loading in C57BL/6J and C3H/HeJ mice intercross.
Bone 2006;39(3):634-43.
2006: Jon E Wergedal; Cheryl L Ackert-Bicknell; Shirng-Wern Tsaih; Matilda H-C Sheng; Renhua Li; Subburamen Mohan; Wesley G Beamer; Gary Churchill; David J Baylink
Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(8):1256-66.
2006: Renhua Li; Shirng-Wern Tsaih; Keith Shockley; Ioannis Stylianou; Jon E Wergedal; Beverly Paigen; Gary Churchill
Structural model analysis of multiple quantitative traits.
PLoS genetics 2006;2(7):e114.
2006: Matilda H-C Sheng; K-H William Lau; Subburaman Mohan; David J Baylink; Jon E Wergedal
High osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is associated with low apoptosis in C3H/HeJ osteoblasts.
Calcified tissue international 2006;78(5):293-301.
2006: Charles H Rundle; Hali Wang; Hongrun Yu; Robert B Chadwick; Emile I Davis; Jon E Wergedal; K-H William Lau; Subburaman Mohan; James Ryaby; David J Baylink
Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair.
Bone 2006;38(4):521-9.
2006: Godfred L Masinde; Runzhi Li; Bay Nguyen; Hongrun Yu; Apurva K Srivastava; BOUCHRA EDDERKAOUI; Jon E Wergedal; David J Baylink; Subburaman Mohan
New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129 x 1/SvJ inbred strains of mice.
Functional & integrative genomics 2006;6(2):157-63.
2006: BOUCHRA EDDERKAOUI; David J Baylink; Wesley G Beamer; Jon E Wergedal; Nancy R Dunn; Kathryn L Shultz; Subburaman Mohan
Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(1):97-104.
2005: Chandrasekhar Kesavan; Subburaman Mohan; Susanna Oberholtzer; Jon E Wergedal; David J Baylink
Mechanical loading-induced gene expression and BMD changes are different in two inbred mouse strains.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(5):1951-7.
2005: Subburaman Mohan; Anil Kapoor; Anny Singgih; Zhang Zhang; Tim Taylor; Hongrun Yu; Robert B Chadwick; Yoon-Sok Chung; Yoon-Suk Chung; Leah Rae Donahue; Clifford Rosen; Grace C Crawford; Jon E Wergedal; David J Baylink
Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(9):1597-610.
2005: Apurva K Srivastava; Sonia Kapur; Suburaman Mohan; Hongrun Yu; Sonia Kapur; Jon E Wergedal; David J Baylink
Identification of novel genetic loci for bone size and mechanosensitivity in an ENU mutant exhibiting decreased bone size.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(6):1041-50.
2005: Dervis A M Salih; Subburaman Mohan; Yuji Kasukawa; Gyanendra Tripathi; Fiona A Lovett; Neil F Anderson; Emma J Carter; Jon E Wergedal; David J Baylink; Jennifer M Pell
Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice.
Endocrinology 2005;146(2):931-40.
2005: Jon E Wergedal; Matilda H-C Sheng; Cheryl L Ackert-Bicknell; Wesley G Beamer; David J Baylink
Genetic variation in femur extrinsic strength in 29 different inbred strains of mice is dependent on variations in femur cross-sectional geometry and bone density.
Bone 2005;36(1):111-22.
2004: Matilda H-C Sheng; K-H William Lau; Wesley G Beamer; David J Baylink; Jon E Wergedal
In vivo and in vitro evidence that the high osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is intrinsic to bone cells.
Bone 2004;35(3):711-9.
2004: Xiao S Zhang; Thomas A Linkhart; Shin-Tai Chen; Hairong Peng; Jon E Wergedal; Genevieve G Guttierez; Matilda H-C Sheng; K-H William Lau; David J Baylink
Local ex vivo gene therapy with bone marrow stromal cells expressing human BMP4 promotes endosteal bone formation in mice.
The journal of gene medicine 2004;6(1):4-15.
2003: Jon E Wergedal; Katarina Veskovic; Minea Hellan; Christine Nyght; Wendy Balemans; Cesar Libanati; Filip M Vanhoenacker; Johan Tan; David J Baylink; Wim Van Hul
Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal.
The Journal of clinical endocrinology and metabolism 2003;88(12):5778-83.
2003: Sofia Movérare; Katrien Venken; Anna-Lena Eriksson; Niklas Andersson; Stanko Skrtic; Jon E Wergedal; Subburaman Mohan; Phil Salmon; Roger Bouillon; Jan-�ke GUSTAFSSON; Dirk Vanderschueren; Claes Ohlsson
Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13573-8.
2003: Yuji Kasukawa; David J Baylink; Jon E Wergedal; Yousef G Amaar; Apurva K Srivastava; Rongqing Guo; Subburaman Mohan
Lack of insulin-like growth factor I exaggerates the effect of calcium deficiency on bone accretion in mice.
Endocrinology 2003;144(11):4682-9.
2003: Leah Rae Donahue; Bo Chang; Subburaman Mohan; Naohisa Miyakoshi; Jon E Wergedal; David J Baylink; Norman L Hawes; Clifford J Rosen; Patricia Ward-Bailey; Qing Yin Zheng; Roderick T Bronson; Kenneth R Johnson; Muriel T Davisson
A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(9):1612-21.
2003: Apurva K Srivastava; Subburaman Mohan; Jon E Wergedal; David J Baylink
A genomewide screening of N-ethyl-N-nitrosourea-mutagenized mice for musculoskeletal phenotypes.
Bone 2003;33(2):179-91.
2003: Charles H Rundle; Naohisa Miyakoshi; Yuji Kasukawa; Shin-Tai Chen; Matilda H-C Sheng; Jon E Wergedal; K-H William Lau; David J Baylink
In vivo bone formation in fracture repair induced by direct retroviral-based gene therapy with bone morphogenetic protein-4.
Bone 2003;32(6):591-601.
2003: Godfred L Masinde; Jon E Wergedal; Heather Davidson; Subburaman Mohan; R Li; Xinmin Li; David J Baylink
Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice.
Bone 2003;32(5):554-60.
2003: Subburaman Mohan; Charmaine Richman; Rongqing Guo; Yousef G Amaar; Leah Rae Donahue; Jon E Wergedal; David J Baylink
Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms.
Endocrinology 2003;144(3):929-36.
2002: Jon E Wergedal; Matilda H-C Sheng; Cheryl L Ackert-Bicknell; Wesley G Beamer; David J Baylink
Mouse genetic model for bone strength and size phenotypes: NZB/B1NJ and RF/J inbred strains.
Bone 2002;31(6):670-4.
2002: Godfred L Masinde; Xinmin Li; Weikuan Gu; Jon E Wergedal; Subburaman Mohan; David J Baylink
Quantitative trait loci for bone density in mice: the genes determining total skeletal density and femur density show little overlap in F2 mice.
Calcified tissue international 2002;71(5):421-8.
2002: Charles H Rundle; Naohisa Miyakoshi; Enrique Ramirez; Jon E Wergedal; K-H William Lau; David J Baylink
Expression of the fibroblast growth factor receptor genes in fracture repair.
Clinical orthopaedics and related research 2002;(403):253-63.
2002: Godfred L Masinde; Xinmin Li; Weikuan Gu; Heather Davidson; Melanie Hamilton-Ulland; Jon E Wergedal; Subburaman Mohan; David J Baylink
Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice.
Functional & integrative genomics 2002;2(3):98-104.
2002: R Gysin; Jon E Wergedal; Matilda H-C Sheng; Yuji Kasukawa; Naohisa Miyakoshi; S-T Chen; H Peng; K-H William Lau; Subburaman Mohan; David J Baylink
Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats.
Gene therapy 2002;9(15):991-9.
2002: L Stabnov; Yuji Kasukawa; Rongqing Guo; Yousef G Amaar; Jon E Wergedal; David J Baylink; Subburaman Mohan
Effect of insulin-like growth factor-1 (IGF-1) plus alendronate on bone density during puberty in IGF-1-deficient MIDI mice.
Bone 2002;30(6):909-16.
2002: Xinmin Li; Godfred L Masinde; Weikuan Gu; Jon E Wergedal; Subburaman Mohan; David J Baylink
Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy.
Genomics 2002;79(5):734-40.
2002: Xinmin Li; Godfred L Masinde; Weikuan Gu; Jon E Wergedal; Melanie Hamilton-Ulland; Shizhong Xu; Subburaman Mohan; David J Baylink
Chromosomal regions harboring genes for the work to femur failure in mice.
Functional & integrative genomics 2002;1(6):367-74.
2002: Matilda H-C Sheng; David J Baylink; Wesley G Beamer; Leah Rae Donahue; K-H William Lau; Jon E Wergedal
Regulation of bone volume is different in the metaphyses of the femur and vertebra of C3H/HeJ and C57BL/6J mice.
Bone 2002;30(3):486-91.
2002: Yoshihisa Umemura; David J Baylink; Jon E Wergedal; Subburaman Mohan; Apurva K Srivastava
A time course of bone response to jump exercise in C57BL/6J mice.
Journal of bone and mineral metabolism 2002;20(4):209-15.
2001: H Peng; Shin-Tai Chen; Jon E Wergedal; J M Polo; Jiing-Kuan Yee; K-H William Lau; David J Baylink
Development of an MFG-based retroviral vector system for secretion of high levels of functionally active human BMP4.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(2):95-104.
2001: Xinmin Li; Subburaman Mohan; Weikuan Gu; Jon E Wergedal; David J Baylink
Quantitative assessment of forearm muscle size, forelimb grip strength, forearm bone mineral density, and forearm bone size in determining humerus breaking strength in 10 inbred strains of mice.
Calcified tissue international 2001;68(6):365-9.
2001: Charmaine Richman; S Kutilek; Naohisa Miyakoshi; Apurva K Srivastava; Wesley G Beamer; Leah Rae Donahue; CJ Rosen; Jon E Wergedal; David J Baylink; Subburaman Mohan
Postnatal and pubertal skeletal changes contribute predominantly to the differences in peak bone density between C3H/HeJ and C57BL/6J mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(2):386-97.
2000: Subburaman Mohan; S Kutilek; C Zhang; H G Shen; Y Kodama; Apurva K Srivastava; Jon E Wergedal; Wesley G Beamer; David J Baylink
Comparison of bone formation responses to parathyroid hormone(1-34), (1-31), and (2-34) in mice.
Bone 2000;27(4):471-8.
2000: Y Kodama; Naohisa Miyakoshi; Thomas A Linkhart; Jon E Wergedal; A Srivastava; Wesley G Beamer; Leah Rae Donahue; C Rosen; David J Baylink; J Farley
Effects of dietary calcium depletion and repletion on dynamic determinants of tibial bone volume in two inbred strains of mice.
Bone 2000;27(3):445-52.
2000: Apurva K Srivastava; G Castillo; Jon E Wergedal; Subburaman Mohan; David J Baylink
Development and application of a synthetic peptide-based osteocalcin assay for the measurement of bone formation in mouse serum.
Calcified tissue international 2000;67(3):255-9.
2000: Apurva K Srivastava; S Bhattacharyya; G Castillo; Jon E Wergedal; Subburaman Mohan; David J Baylink
Development and application of a serum C-telopeptide and osteocalcin assay to measure bone turnover in an ovariectomized rat model.
Calcified tissue international 2000;66(6):435-42.
1999: Matilda H-C Sheng; David J Baylink; Wesley G Beamer; Leah Rae Donahue; CJ Rosen; K-H William Lau; Jon E Wergedal
Histomorphometric studies show that bone formation and bone mineral apposition rates are greater in C3H/HeJ (high-density) than C57BL/6J (low-density) mice during growth.
Bone 1999;25(4):421-9.
1999: Y Kodama; HP Dimai; Jon E Wergedal; Matilda H-C Sheng; R Malpe; S Kutilek; Wesley G Beamer; Leah Rae Donahue; C Rosen; David J Baylink; J Farley
Cortical tibial bone volume in two strains of mice: effects of sciatic neurectomy and genetic regulation of bone response to mechanical loading.
Bone 1999;25(2):183-90.
1999: Thomas A Linkhart; SG Linkhart; Y Kodama; John R Farley; HP Dimai; Kenneth Wright; Jon E Wergedal; Matilda H-C Sheng; Wesley G Beamer; Leah Rae Donahue; CJ Rosen; David J Baylink
Osteoclast formation in bone marrow cultures from two inbred strains of mice with different bone densities.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(1):39-46.
1997: R Malpe; David J Baylink; Thomas A Linkhart; Jon E Wergedal; Subburaman Mohan
Insulin-like growth factor (IGF)-I, -II, IGF binding proteins (IGFBP)-3, -4, and -5 levels in the conditioned media of normal human bone cells are skeletal site-dependent.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(3):423-30.
1996: K-H William Lau; X D Song; M Ochi; Jon E Wergedal
Mitogenic action of hydrochlorothiazide on human osteoblasts in vitro: requirement for platelet-derived growth factor.
Calcified tissue international 1996;59(6):505-10.
1996: S Hilliker; Jon E Wergedal; H E Gruber; P Bettica; D J Baylink
Truncation of the amino terminus of PTH alters its anabolic activity on bone in vivo.
Bone 1996;19(5):469-77.
1995: Christian Kasperk; Jon E Wergedal; D Strong; J Farley; K Wangerin; H Gropp; Reinhard Ziegler; David J Baylink
Human bone cell phenotypes differ depending on their skeletal site of origin.
The Journal of clinical endocrinology and metabolism 1995;80(8):2511-7.
1995: J E Looney; H K Yoon; M Fischer; S M Farley; John R Farley; Jon E Wergedal; David J Baylink
Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women.
The Journal of clinical endocrinology and metabolism 1995;80(7):2158-62.
1995: D J Baylink; Jon E Wergedal; John R Farley; T A Einhorn
On fluoride and bone strength.
Calcified tissue international 1995;56(5):415-8.
1995: T Ohta; Jon E Wergedal; T Matsuyama; David J Baylink; K-H William Lau
Phenytoin and fluoride act in concert to stimulate bone formation and to increase bone volume in adult male rats.
Calcified tissue international 1995;56(5):390-7.
1995: M W Lundy; M Stauffer; Jon E Wergedal; David J Baylink; J D Featherstone; S F Hodgson; Lawrence B. Riggs
Histomorphometric analysis of iliac crest bone biopsies in placebo-treated versus fluoride-treated subjects.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1995;5(2):115-29.
1995: T Ohta; Jon E Wergedal; H E Gruber; David J Baylink; K-H William Lau
Low dose phenytoin is an osteogenic agent in the rat.
Calcified tissue international 1995;56(1):42-8.
1994: John R Farley; SL Hall; M A Tanner; Jon E Wergedal
Specific activity of skeletal alkaline phosphatase in human osteoblast-line cells regulated by phosphate, phosphate esters, and phosphate analogs and release of alkaline phosphatase activity inversely regulated by calcium.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(4):497-508.
1993: S G Linkhart; Thomas A Linkhart; A K Taylor; Jon E Wergedal; P Bettica; David J Baylink
Synthetic peptide-based immunoassay for amino-terminal propeptide of type I procollagen: application for evaluation of bone formation.
Clinical chemistry 1993;39(11 Pt 1):2254-8.
1993: John R Farley; SL Hall; S Herring; Cesar Libanati; Jon E Wergedal
Reference standards for quantification of skeletal alkaline phosphatase activity in serum by heat inactivation and lectin precipitation.
Clinical chemistry 1993;39(9):1878-84.
1993: R Knutsen; Jon E Wergedal; T K Sampath; David J Baylink; Subburaman Mohan
Osteogenic protein-1 stimulates proliferation and differentiation of human bone cells in vitro.
Biochemical and biophysical research communications 1993;194(3):1352-8.
1992: Subburaman Mohan; Donna Strong; U G Lempert; F Tremollieres; Jon E Wergedal; David J Baylink
Studies on regulation of insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-4 production in human bone cells.
Acta endocrinologica 1992;127(6):555-64.
1992: K-H William Lau; A B Thomas; A Yoo; T S Nguyen; Jon E Wergedal
Conversion of skeletal tartrate-sensitive acid phosphatases into tartrate-resistant isoenzymes in vitro.
The International journal of biochemistry 1992;24(11):1815-24.
1992: S M Farley; Jon E Wergedal; John R Farley; G N Javier; E E Schulz; J R Talbot; Cesar Libanati; L Lindegren; M Bock; M M Goette
Spinal fractures during fluoride therapy for osteoporosis: relationship to spinal bone density.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1992;2(5):213-8.
1992: M W Lundy; J E Russell; J Avery; Jon E Wergedal; David J Baylink
Effect of sodium fluoride on bone density in chickens.
Calcified tissue international 1992;50(5):420-6.
1992: Jon E Wergedal; K-H William Lau
Human bone cells contain a fluoride sensitive acid phosphatase: evidence that this enzyme functions at neutral pH as a phosphotyrosyl protein phosphatase.
Clinical biochemistry 1992;25(1):47-53.
1992: Jon E Wergedal; T Matsuyama; Donna Strong
Differentiation of normal human bone cells by transforming growth factor-beta and 1,25(OH)2 vitamin D3.
Metabolism: clinical and experimental 1992;41(1):42-8.
1991: John R Farley; SL Hall; S Herring; N M Tarbaux; T Matsuyama; Jon E Wergedal
Skeletal alkaline phosphatase specific activity is an index of the osteoblastic phenotype in subpopulations of the human osteosarcoma cell line SaOS-2.
Metabolism: clinical and experimental 1991;40(7):664-71.
1991: John R Farley; Jon E Wergedal; SL Hall; S Herring; N M Tarbaux
Calcitonin has direct effects on 3[H]-thymidine incorporation and alkaline phosphatase activity in human osteoblast-line cells.
Calcified tissue international 1991;48(5):297-301.
1991: H Tanimoto; K-H William Lau; S K Nishimoto; Jon E Wergedal; David J Baylink
Evaluation of the usefulness of serum phosphatases and osteocalcin as serum markers in a calcium depletion-repletion rat model.
Calcified tissue international 1991;48(2):101-10.
1991: M W Lundy; T Hendrix; Jon E Wergedal; David J Baylink
Growth factor-induced proliferation of osteoblasts measured by bromodeoxyuridine immunocytochemistry.
Growth factors (Chur, Switzerland) 1991;4(4):257-64.
1991: Donna Strong; A L Beachler; Jon E Wergedal; Thomas A Linkhart
Insulinlike growth factor II and transforming growth factor beta regulate collagen expression in human osteoblastlike cells in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(1):15-23.
1991: J J Stepan; Subburaman Mohan; J C Jennings; Jon E Wergedal; A K Taylor; David J Baylink
Quantitation of growth factors in ossein-mineral-compound.
Life sciences 1991;49(13):PL79-84.
1990: T Matsuyama; K-H William Lau; Jon E Wergedal
Monolayer cultures of normal human bone cells contain multiple subpopulations of alkaline phosphatase positive cells.
Calcified tissue international 1990;47(5):276-83.
1990: Christian Kasperk; R Fitzsimmons; D Strong; S Mohan; J Jennings; Jon E Wergedal; David J Baylink
Studies of the mechanism by which androgens enhance mitogenesis and differentiation in bone cells.
The Journal of clinical endocrinology and metabolism 1990;71(5):1322-9.
1990: E E Schulz; C Flowers; Donald D Sauser; B N Brin; Jon E Wergedal; David J Baylink
The causes of bone scintigram hot spots in fluoride-treated osteoporotic patients.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5 Suppl 1():S201-4.
1990: Jon E Wergedal; Subburaman Mohan; M Lundy; David J Baylink
Skeletal growth factor and other growth factors known to be present in bone matrix stimulate proliferation and protein synthesis in human bone cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(2):179-86.
1990: Christian Kasperk; Jon E Wergedal; S Mohan; D L Long; K-H William Lau; David J Baylink
Interactions of growth factors present in bone matrix with bone cells: effects on DNA synthesis and alkaline phosphatase.
Growth factors (Chur, Switzerland) 1990;3(2):147-58.
1989: Subburaman Mohan; C M Bautista; Jon E Wergedal; David J Baylink
Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8338-42.
1989: Christian Kasperk; Jon E Wergedal; John R Farley; Thomas A Linkhart; Russell T Turner; David J Baylink
Androgens directly stimulate proliferation of bone cells in vitro.
Endocrinology 1989;124(3):1576-8.
1989: M W Lundy; Jon E Wergedal; E Teubner; J Burnell; D Sherrard; David J Baylink
The effect of prolonged fluoride therapy for osteoporosis: bone composition and histology.
Bone 1989;10(5):321-7.
1988: Jon E Wergedal; K-H William Lau; David J Baylink
Fluoride and bovine bone extract influence cell proliferation and phosphatase activities in human bone cell cultures.
Clinical orthopaedics and related research 1988;(233):274-82.
1988: C V Odvina; Jon E Wergedal; Cesar Libanati; E E Schulz; David J Baylink
Relationship between trabecular vertebral body density and fractures: a quantitative definition of spinal osteoporosis.
Metabolism: clinical and experimental 1988;37(3):221-8.
1987: K-H William Lau; T Onishi; Jon E Wergedal; F R Singer; D J Baylink
Characterization and assay of tartrate-resistant acid phosphatase activity in serum: potential use to assess bone resorption.
Clinical chemistry 1987;33(4):458-62.
1987: S M Farley; Jon E Wergedal; L C Smith; M W Lundy; John R Farley; David J Baylink
Fluoride therapy for osteoporosis: characterization of the skeletal response by serial measurements of serum alkaline phosphatase activity.
Metabolism: clinical and experimental 1987;36(3):211-8.
1986: Jon E Wergedal; S Mohan; A K Taylor; D J Baylink
Skeletal growth factor is produced by human osteoblast-like cells in culture.
Biochimica et biophysica acta 1986;889(2):163-70.
1985: G B McDonald; K H Lau; A L Schy; Jon E Wergedal; D J Baylink
Intestinal metabolism and portal venous transport of 1,25(OH)2D3, 25(OH)D3, and vitamin D3 in the rat.
The American journal of physiology 1985;248(6 Pt 1):G633-8.
1984: S Mohan; T Linkhart; Jon E Wergedal; D Baylink
A correction: inhibitory activity in the conditioned medium of embryonic chick bones is due to thymidine.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1984;177(2):290-5.
1983: John R Farley; Jon E Wergedal; D J Baylink
Fluoride directly stimulates proliferation and alkaline phosphatase activity of bone-forming cells.
Science (New York, N.Y.) 1983;222(4621):330-2.
1982: J R Farley; T Masuda; Jon E Wergedal; D J Baylink
Human skeletal growth factor: characterization of the mitogenic effect on bone cells in vitro.
Biochemistry 1982;21(14):3508-13.