FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Michael Wermann

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Living Beings

Co-author Network

Publications

TOP 3
Birgit Koch; Stephan Schilling; Michael Wermann; Mirko Buchholz; Ulrich Heiser; Hans-Ulrich Demuth
Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development.
Birgit Koch; Petr Kolenko; Christoph Parthier; Jens-Ulrich Rahfeld; Gunter Reuter; Stephan Schilling; Milton T Stubbs; Michael Wermann; David Ruiz Carrillo; Mirko Buchholz; Hans-Ulrich Demuth
Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs.
Holger Cynis; Margreet R De Vries; Sabine Berg; Rico Eichentopf; Ernst-Joachim Freyse; Daniel Friedrich; Kathrin Gans; Sigrid Graubner; Monique Haegele; Ulrich Heiser; Isabel Hesse; Torsten Hoffmann; Wolfgang Jagla; Astrid Kehlen; Martin Kleinschmidt; Anke Müller; Paul H A Quax; Jens-Ulrich Rahfeld; Stephan Schilling; Reinhard Sedlmeier; Franziska Seifert; Anett Stephan; Daniela Trautwein; Michael Wermann; Raik Wolf; Ulrich Wollert; Hans-Ulrich Demuth
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Michael Wermann (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Birgit Koch; Stephan Schilling; Michael Wermann; Mirko Buchholz; Ulrich Heiser; Hans-Ulrich Demuth
Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development.
Chemical biology & drug design 2012;80(6):937-46.
2012: Birgit Koch; Petr Kolenko; Christoph Parthier; Jens-Ulrich Rahfeld; Gunter Reuter; Stephan Schilling; Milton T Stubbs; Michael Wermann; David Ruiz Carrillo; Mirko Buchholz; Hans-Ulrich Demuth
Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs.
Biochemistry 2012;51(37):7383-92.
2011: Holger Cynis; Margreet R De Vries; Sabine Berg; Rico Eichentopf; Ernst-Joachim Freyse; Daniel Friedrich; Kathrin Gans; Sigrid Graubner; Monique Haegele; Ulrich Heiser; Isabel Hesse; Torsten Hoffmann; Wolfgang Jagla; Astrid Kehlen; Martin Kleinschmidt; Anke Müller; Paul H A Quax; Jens-Ulrich Rahfeld; Stephan Schilling; Reinhard Sedlmeier; Franziska Seifert; Anett Stephan; Daniela Trautwein; Michael Wermann; Raik Wolf; Ulrich Wollert; Hans-Ulrich Demuth
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.
EMBO molecular medicine 2011;3(9):545-58.
2011: David Ruiz-Carrillo; Stephan Schilling; Milton T Stubbs; Michael Wermann; Ulrich Heiser; Birgit Koch; Hans-Henning Ludwig; Christoph Parthier; Jens-Ulrich Rahfeld; Mirko Buchholz; Tresfore Dambe; Hans-Ulrich Demuth
Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.
Biochemistry 2011;50(28):6280-8.
2011: Leona Wagner; Michael Wermann; Torsten Hoffmann; Jens-Ulrich Rahfeld; Fred Rosche; Hans-Ulrich Demuth
Isolation of dipeptidyl peptidase IV (DP 4) isoforms from porcine kidney by preparative isoelectric focusing to improve crystallization.
Biological chemistry 2011;392(7):665-77.
2008: Stephan Schilling; Thomas Appl; Torsten Hoffmann; Holger Cynis; Katrin Schulz; Wolfgang Jagla; Daniel Friedrich; Michael Wermann; Mirko Buchholz; Ulrich Heiser; Stephan von Hörsten; Hans-Ulrich Demuth
Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.
Journal of neurochemistry 2008;106(3):1225-36.
2008: Holger Cynis; Jens-Ulrich Rahfeld; Anett Stephan; Astrid Kehlen; Birgit Koch; Michael Wermann; Hans-Ulrich Demuth; Stephan Schilling
Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.
Journal of molecular biology 2008;379(5):966-80.
2007: Stephan Schilling; Christiane Lindner; Birgit Koch; Michael Wermann; Jens-Ulrich Rahfeld; Alex von Bohlen; Thomas Rudolph; Gunter Reuter; Hans-Ulrich Demuth
Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.
Biochemistry 2007;46(38):10921-30.
2007: Daniel Friedrich; Torsten Hoffmann; Joachim Bär; Michael Wermann; Susanne Manhart; Ulrich Heiser; Hans-Ulrich Demuth
Does human attractin have DP4 activity?
Biological chemistry 2007;388(2):155-62.
2007: Stephan Schilling; Irene Stenzel; Alex von Bohlen; Michael Wermann; Katrin Schulz; Hans-Ulrich Demuth; Claus Wasternack
Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions.
Biological chemistry 2007;388(2):145-53.
2005: Stephan Schilling; Holger Cynis; Alex von Bohlen; Torsten Hoffmann; Michael Wermann; Ulrich Heiser; Mirko Buchholz; Katrin Zunkel; Hans-Ulrich Demuth
Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.
Biochemistry 2005;44(40):13415-24.
2003: Stephan Schilling; André J Niestroj; Jens-Ulrich Rahfeld; Torsten Hoffmann; Michael Wermann; Katrin Zunkel; Claus Wasternack; Hans-Ulrich Demuth
Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators.
The Journal of biological chemistry 2003;278(50):49773-9.
2003: Joachim Bär; Anja Weber; Torsten Hoffmann; Jörg Stork; Michael Wermann; Leona Wagner; Susanne Aust; Bernd Gerhartz; Hans-Ulrich Demuth
Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme.
Biological chemistry 2003;384(12):1553-63.
2003: Michael Engel; Torsten Hoffmann; Leona Wagner; Michael Wermann; Ulrich Heiser; Reiner Kiefersauer; Robert Huber; Wolfram Bode; Hans-Ulrich Demuth; Hans Brandstetter
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5063-8.
2002: Simon Hinke; Christopher H S McIntosh; Torsten Hoffmann; Kerstin Kühn-Wache; Leona Wagner; Joachim Bär; Susanne Manhart; Michael Wermann; Raymond A Pederson; Hans-Ulrich Demuth
On combination therapy of diabetes with metformin and dipeptidyl peptidase IV inhibitors.
Diabetes care 2002;25(8):1490-1; author reply 1491-2.
2002: Stephan Schilling; Torsten Hoffmann; Michael Wermann; Ulrich Heiser; Claus Wasternack; Hans-Ulrich Demuth
Continuous spectrometric assays for glutaminyl cyclase activity.
Analytical biochemistry 2002;303(1):49-56.