John West

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Chanas Simon A; Collinson J Martin; Ramaesh Thaya; Dorà Natalie; Kleinjan Dirk A; Hill Robert E; West John D
Effects of elevated Pax6 expression and genetic background on mouse eye development.
Ramaesh Thaya; Williams Steven E; Paul Catriona; Ramaesh Kanna; Dhillon Baljean; West John D
Histopathological characterisation of effects of the mouse Pax6(Leca4) missense mutation on eye development.
Leiper Lucy J; Ou Jingxing; Walczysko Petr; Kucerova Romana; Lavery Derek N; West John D; Collinson J Martin
Control of patterns of corneal innervation by Pax6.

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All Publications

2009: Chanas Simon A; Collinson J Martin; Ramaesh Thaya; Dorà Natalie; Kleinjan Dirk A; Hill Robert E; West John D
Effects of elevated Pax6 expression and genetic background on mouse eye development.
Investigative ophthalmology & visual science 2009;50(9):4045-59.
2009: Ramaesh Thaya; Williams Steven E; Paul Catriona; Ramaesh Kanna; Dhillon Baljean; West John D
Histopathological characterisation of effects of the mouse Pax6(Leca4) missense mutation on eye development.
Experimental eye research 2009;89(2):263-73.
2009: Leiper Lucy J; Ou Jingxing; Walczysko Petr; Kucerova Romana; Lavery Derek N; West John D; Collinson J Martin
Control of patterns of corneal innervation by Pax6.
Investigative ophthalmology & visual science 2009;50(3):1122-8.
2009: Mort Richard L; Ramaesh Thaya; Kleinjan Dirk A; Morley Steven D; West John D
Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium.
BMC developmental biology 2009;9():4.
2008: Dorà Natalie; Ou Jingxing; Kucerova Romana; Parisi Ida; West John D; Collinson J Martin
PAX6 dosage effects on corneal development, growth, and wound healing.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(5):1295-306.
2007: Everett Clare A; Keighren Margaret A; Flockhart Jean H; West John D
Evaluation of triploid<-->diploid and trisomy-3<-->diploid mouse chimeras as models for investigating how lineage restriction occurs in confined placental mosaicism.
Reproduction (Cambridge, England) 2007;134(6):799-809.
2007: Manuel Martine; Georgala Petrina A; Carr Catherine B; Chanas Simon; Kleinjan Dirk A; Martynoga Ben; Mason John O; Molinek Michael; Pinson Jeni; Pratt Thomas; Quinn Jane C; Simpson T Ian; Tyas David A; van Heyningen Veronica; West John D; Price David J
Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization.
Development (Cambridge, England) 2007;134(3):545-55.
2007: Quinn Jane C; Molinek Michael; Martynoga Ben S; Zaki Paulette A; Faedo Andrea; Bulfone Alessandro; Hevner Robert F; West John D; Price David J
Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism.
Developmental biology 2007;302(1):50-65.
2006: Ramaesh Thaya; Ramaesh Kanna; Leask Rosemary; Springbett Anthea; Riley Simon C; Dhillon Baljean; West John D
Increased apoptosis and abnormal wound-healing responses in the heterozygous Pax6+/- mouse cornea.
Investigative ophthalmology & visual science 2006;47(5):1911-7.
2005: Mackay Gillian E; West John D
Fate of tetraploid cells in 4n<-->2n chimeric mouse blastocysts.
Mechanisms of development 2005;122(12):1266-81.
2005: Ramaesh Thaya; Ramaesh Kanna; Martin Collinson J; Chanas Simon A; Dhillon Baljean; West John D
Developmental and cellular factors underlying corneal epithelial dysgenesis in the Pax6+/- mouse model of aniridia.
Experimental eye research 2005;81(2):224-35.
2005: MacKay Gillian E; Keighren Margaret A; Wilson Linda; Pratt Thomas; Flockhart Jean H; Mason John O; Price David J; West John D
Evaluation of the mouse TgTP6.3 tauGFP transgene as a lineage marker in chimeras.
Journal of anatomy 2005;206(1):79-92.
2004: Morley S D; Chang S P; Tan S S; West J D
Validity of the 21-OH/LacZ transgenic mouse as a model for studying adrenocortical cell lineage.
Endocrine research 2004;30(4):513-9.
2004: Everett Clare A; Auchincloss Catherine A; Kaufman Matthew H; Abbott Catherine M; West John D
Genetic influences on ovulation of primary oocytes in LT/Sv strain mice.
Reproduction (Cambridge, England) 2004;128(5):565-71.
2004: Ramaesh K; Ramaesh T; West J D; Dhillon B
Immunolocalisation of leukaemia inhibitory factor in the cornea.
Eye (London, England) 2004;18(10):1006-9.
2004: Collinson J Martin; Chanas Simon A; Hill Robert E; West John D
Corneal development, limbal stem cell function, and corneal epithelial cell migration in the Pax6(+/-) mouse.
Investigative ophthalmology & visual science 2004;45(4):1101-8.
2004: Collinson J Martin; Hill Robert E; West John D
Analysis of mouse eye development with chimeras and mosaics.
The International journal of developmental biology 2004;48(8-9):793-804.
2003: Sinawat Supat; Hsaio Wei-Chih; Flockhart Jean H; Kaufman Matthew H; Keith John; West John D
Fetal abnormalities produced after preimplantation exposure of mouse embryos to ammonium chloride.
Human reproduction (Oxford, England) 2003;18(10):2157-65.
2003: James Roberta M; Arends Mark J; Plowman Sarah J; Brooks David G; Miles Colin G; West John D; Patek Charles E
K-ras proto-oncogene exhibits tumor suppressor activity as its absence promotes tumorigenesis in murine teratomas.
Molecular cancer research : MCR 2003;1(11):820-5.
2003: Keighren Margaret A; Macfadyen Leah P; Hill Alan S; Patek Charles E; Telfer Evelyn E; West John D
Polyploid cells in the mouse ovary.
Journal of anatomy 2003;202(6):563-71.
2003: Ramaesh Thaya; Collinson J Martin; Ramaesh Kanna; Kaufman Matthew H; West John D; Dhillon Baljean
Corneal abnormalities in Pax6+/- small eye mice mimic human aniridia-related keratopathy.
Investigative ophthalmology & visual science 2003;44(5):1871-8.
2003: Collinson J Martin; Quinn Jane C; Hill Robert E; West John D
The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo.
Developmental biology 2003;255(2):303-12.
2003: Talamillo Ana; Quinn Jane C; Collinson J Martin; Caric Damira; Price David J; West John D; Hill Robert E
Pax6 regulates regional development and neuronal migration in the cerebral cortex.
Developmental biology 2003;255(1):151-63.
2002: Morley Steven D; O'Donohoe Elizabeth A; Hughes Katherine E; Irving Catherine; Willis Sarah M; Heasman Sarah; West John D
Mosaic patch patterns in chimeric and transgenic mice suggest that directional growth in the adrenal cortex begins in the perinatal period.
Endocrine research 2002;28(4):657-62.
2002: Kelly A; West J D
Survival and normal function of glycolysis-deficient mouse oocytes.
Reproduction (Cambridge, England) 2002;124(4):469-73.
2002: Pratt Thomas; Quinn Jane C; Simpson T Ian; West John D; Mason John O; Price David J
Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(19):8523-31.
2002: Collinson J Martin; Morris Lucy; Reid Alasdair I; Ramaesh Thaya; Keighren Margaret A; Flockhart Jean H; Hill Robert E; Tan Seong-Seng; Ramaesh Kanna; Dhillon Baljean; West John D
Clonal analysis of patterns of growth, stem cell activity, and cell movement during the development and maintenance of the murine corneal epithelium.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;224(4):432-40.
2002: Kelly Annemarie; West John D
Developmental potential and survival of glycolysis-deficient cells in fetal mouse chimeras.
Genesis (New York, N.Y. : 2000) 2002;33(1):29-39.
2002: Jaskoll Tina; Zhou Yan Min; Chai Yang; Makarenkova Helen P; Collinson J Martin; West John D; Hajihosseini Mohammad K; Lee Jina; Melnick Michael
Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice.
Cells, tissues, organs 2002;170(2-3):83-98.
2001: Collinson J M; Quinn J C; Buchanan M A; Kaufman M H; Wedden S E; West J D; Hill R E
Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9688-93.
2001: Tang P C; West J D
Size regulation does not cause the composition of mouse chimaeras to become unbalanced.
The International journal of developmental biology 2001;45(3):583-90.
2000: Tang P C; West J D
The effects of embryo stage and cell number on the composition of mouse aggregation chimaeras.
Zygote (Cambridge, England) 2000;8(3):235-43.
2000: Everett C A; Stark M H; West J D; Davidson D; Baldock R A
Three-dimensional reconstruction of tetraploid<-->diploid chimaeric mouse blastocysts.
Journal of anatomy 2000;196 ( Pt 3)():341-6.
2000: Collinson J M; Hill R E; West J D
Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of the murine eye.
Development (Cambridge, England) 2000;127(5):945-56.
2000: Ellison A R; West J D; Spears N; Murray A; Everett C A; Bishop J O
Failure of founder transgenic male mice to transmit an attenuated HSV thymidine kinase transgene results from mosaicism and sperm competition.
Molecular reproduction and development 2000;55(3):249-55.
2000: Tang P C; Ritchie W A; Wilmut I; West J D
The effects of cell size and ploidy on cell allocation in mouse chimaeric blastocysts.
Zygote (Cambridge, England) 2000;8(1):33-43.
1999: Borthwick D W; West J D; Keighren M A; Flockhart J H; Innes B A; Dorin J R
Murine submucosal glands are clonally derived and show a cystic fibrosis gene-dependent distribution pattern.
American journal of respiratory cell and molecular biology 1999;20(6):1181-9.
1998: Everett C A; West J D
Evidence for selection against tetraploid cells in tetraploid<-->diploid mouse chimaeras before the late blastocyst stage.
Genetical research 1998;72(3):225-8.
1997: Quinn J C; West J D; Kaufman M H
Genetic background effects on dental and other craniofacial abnormalities in homozygous small eye (Pax6Sey/Pax6Sey) mice.
Anatomy and embryology 1997;196(4):311-21.
1997: West J D; Hodson B A; Keighren M A
Quantitative and spatial information on the composition of chimaeric fetal mouse eyes from single histological sections.
Development, growth & differentiation 1997;39(3):305-17.
1996: Kelly A; West J D
Genetic evidence that glycolysis is necessary for gastrulation in the mouse.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;207(3):300-8.
1996: West J D; Keighren M A; Flockhart J H
A quantitative test for developmental neutrality of a transgenic lineage marker in mouse chimaeras.
Genetical research 1996;67(2):135-46.
1996: Everett C A; West J D
The influence of ploidy on the distribution of cells in chimaeric mouse blastocysts.
Zygote (Cambridge, England) 1996;4(1):59-66.
1995: West J D; Flockhart J H; Keighren M
Biochemical evidence for cell fusion in placentas of mouse aggregation chimeras.
Developmental biology 1995;168(1):76-85.
1995: West J D; Flockhart J H; Kissenpfennig A
A maternal genetic effect on the composition of mouse aggregation chimaeras.
Genetical research 1995;65(1):29-40.
1995: James R M; Klerkx A H; Keighren M; Flockhart J H; West J D
Restricted distribution of tetraploid cells in mouse tetraploid<==>diploid chimaeras.
Developmental biology 1995;167(1):213-26.
1994: James R M; West J D
A chimaeric animal model for confined placental mosaicism.
Human genetics 1994;93(5):603-4.
1994: West J D; Flockhart J H
Genotypically unbalanced diploid<==>diploid foetal mouse chimaeras: possible relevance to human confined mosaicism.
Genetical research 1994;63(2):87-99.
1994: Johnstone F D; West J D; Steel J; Whitehouse D B; Drago G A; Greer I A; Prescott R J
Lack of association between maternal phosphoglucomutase-1 phenotype and fetal macrosomia in diabetic pregnancy.
British journal of obstetrics and gynaecology 1994;101(3):239-45.
1993: West J D; Webb S; Kaufman M H
Inheritance of a meiotic abnormality that causes the ovulation of primary oocytes and the production of digynic triploid mice.
Genetical research 1993;62(3):183-93.
1993: Johnstone F D; West J D; Prescott R J; Steel J M; Flockhart J A; Greer I A; Drago G A; Whitehouse D B
Fetal growth, gestation length and phosphoglucomutase-1 phenotype.
Disease markers 1993;11(5-6):251-62.
1993: West J D
A genetically defined animal model of anembryonic pregnancy.
Human reproduction (Oxford, England) 1993;8(8):1316-23.
1993: Keighren M; West J D
Analysis of cell ploidy in histological sections of mouse tissues by DNA-DNA in situ hybridization with digoxigenin-labelled probes.
The Histochemical journal 1993;25(1):30-44.
1992: James R M; Kaufman M H; Webb S; West J D
Electrofusion of mouse embryos results in uniform tetraploidy and not tetraploid/diploid mosaicism.
Genetical research 1992;60(3):185-94.
1991: West J D; Ansell J D; Flockhart J H
Expression of glucose phosphate isomerase in interspecific hybrid (Mus musculus x Mus caroli) mouse embryos.
Developmental genetics 1991;12(6):403-14.
1990: West J D; Flockhart J H; Peters J; Ball S T
Death of mouse embryos that lack a functional gene for glucose phosphate isomerase.
Genetical research 1990;56(2-3):223-36.
1990: Ellis P M; West J D; West K M; Murray R S; Coyle M C
Relevance to prenatal diagnosis of the identification of a human Y/autosome translocation by Y-chromosome-specific in situ hybridisation.
Molecular reproduction and development 1990;25(1):37-41.
1989: West J D; Flockhart J H
Genetic differences in glucose phosphate isomerase activity among mouse embryos.
Development (Cambridge, England) 1989;107(3):465-72.
1989: West J D; Flockhart J H
Non-additive inheritance of glucose phosphate isomerase activity in mice heterozygous at the Gpi-1s structural locus.
Genetical research 1989;54(1):27-35.
1989: West J D; Flockhart J H; Angell R R; Hillier S G; Thatcher S S; Glasier A F; Rodger M W; Baird D T
Glucose phosphate isomerase activity in mouse and human eggs and pre-embryos.
Human reproduction (Oxford, England) 1989;4(1):82-5.
1989: West J D
The use of DNA probes in preimplantation and prenatal diagnosis.
Molecular reproduction and development 1989;1(2):138-45.
1989: West J D; Gosden C M; Gosden J R; West K M; Davidson Z; Davidson C; Nicolaides K H
Sexing the human fetus and identification of polyploid nuclei by DNA-DNA in situ hybridisation in interphase nuclei.
Molecular reproduction and development 1989;1(2):129-37.
1989: West J D; West K M; Aitken R J
Detection of Y-bearing spermatozoa by DNA-DNA in situ hybridisation.
Molecular reproduction and development 1989;1(3):201-7.
1988: Thatcher S S; Angell R E; West J D; Glasier A F; Kelly R W; Hillier S G; Baird D T
Effects of preovulatory tamoxifen in regularly cycling women on folliculogenesis, oocyte recovery and luteal function.
Human reproduction (Oxford, England) 1988;3(8):935-8.
1988: West J D; Gosden J R; Angell R R; West K M; Glasier A F; Thatcher S S; Baird D T
Sexing whole human pre-embryos by in-situ hybridization with a Y-chromosome specific DNA probe.
Human reproduction (Oxford, England) 1988;3(8):1010-9.
1988: Angell R R; Hillier S G; West J D; Glasier A F; Rodger M W; Baird D T
Chromosome anomalies in early human embryos.
Journal of reproduction and fertility. Supplement 1988;36():73-81.
1987: Angell R R; Sumner A T; West J D; Thatcher S S; Glasier A F; Baird D T
Post-fertilization polyploidy in human preimplantation embryos fertilized in-vitro.
Human reproduction (Oxford, England) 1987;2(8):721-7.
1987: West J D; Leask R; Flockhart J H; Fisher G
High activity of an unstable form of glucose phosphate isomerase in the mouse.
Biochemical genetics 1987;25(7-8):543-61.
1987: West J D; Gosden J R; Angell R R; Hastie N D; Thatcher S S; Glasier A F; Baird D T
Sexing the human pre-embryo by DNA-DNA in-situ hybridisation.
Lancet 1987;1(8546):1345-7.
1986: West J D; Leask R; Green J F
Quantification of the transition from oocyte-coded to embryo-coded glucose phosphate isomerase in mouse embryos.
Journal of embryology and experimental morphology 1986;97():225-37.
1983: West J D; Green J F
The transition from oocyte-coded to embryo-coded glucose phosphate isomerase in the early mouse embryo.
Journal of embryology and experimental morphology 1983;78():127-40.

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