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John West

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Panagiotis Douvaras; Weijia Liu; Lisa McKie; Steven D Morley; Richard L Mort; Sally H Cross; Katrine M West; John D West
Normal X-inactivation mosaicism in corneas of heterozygous FlnaDilp2/+ female mice--a model of human filamin A (FLNA) diseases.
Romana Kucerova; Lucy J Leiper; Christina Lowes; Colin D McCaig; Richard L Mort; Carlos Neves; Ann M Rajnicek; Petr Walczysko; Karen Wallace; John D West; Min Zhao; Freyja Bruce; Natalie Dorà; Paul Fowler; J Martin Collinson
Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium.
Panagiotis Douvaras; Robert E Hill; Sheila Webb; Natalie Dorà; Julia R Dorin; Duncan A Whitaker; John D West
Rare corneal clones in mice suggest an age-related decrease of stem cell activity and support the limbal epithelial stem cell hypothesis.

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2012: Panagiotis Douvaras; Weijia Liu; Lisa McKie; Steven D Morley; Richard L Mort; Sally H Cross; Katrine M West; John D West
Normal X-inactivation mosaicism in corneas of heterozygous FlnaDilp2/+ female mice--a model of human filamin A (FLNA) diseases.
BMC research notes 2012;5():122.
2012: Romana Kucerova; Lucy J Leiper; Christina Lowes; Colin D McCaig; Richard L Mort; Carlos Neves; Ann M Rajnicek; Petr Walczysko; Karen Wallace; John D West; Min Zhao; Freyja Bruce; Natalie Dorà; Paul Fowler; J Martin Collinson
Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium.
Molecular vision 2012;18():139-50.
2012: Panagiotis Douvaras; Robert E Hill; Sheila Webb; Natalie Dorà; Julia R Dorin; Duncan A Whitaker; John D West
Rare corneal clones in mice suggest an age-related decrease of stem cell activity and support the limbal epithelial stem cell hypothesis.
Stem cell research 2012;8(1):109-19.
2011: Benjamin A Hodson; Margaret A Keighren; Anthea Springbett; Mathieu Unbekandt; John D West
Evaluation of methods for one-dimensional spatial analysis of two-dimensional patterns in mouse chimaeras.
Journal of anatomy 2011;219(3):418-37.
2010: Martine Manuel; Ben Martynoga; Tian Yu; John D West; John O Mason; David J Price
The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice.
Development (Cambridge, England) 2010;137(3):487-97.
2009: Simon A Chanas; J Martin Collinson; Thaya Ramaesh; Natalie Dorà; Dirk A Kleinjan; Robert E Hill; John D West
Effects of elevated Pax6 expression and genetic background on mouse eye development.
Investigative ophthalmology & visual science 2009;50(9):4045-59.
2009: Thaya Ramaesh; Steven E Williams; Catriona Paul; Kanna Ramaesh; Baljean Dhillon; John D West
Histopathological characterisation of effects of the mouse Pax6(Leca4) missense mutation on eye development.
Experimental eye research 2009;89(2):263-73.
2009: Lucy J Leiper; Jingxing Ou; Petr Walczysko; Romana Kucerova; Derek N Lavery; John D West; J Martin Collinson
Control of patterns of corneal innervation by Pax6.
Investigative ophthalmology & visual science 2009;50(3):1122-8.
2009: Richard L Mort; Thaya Ramaesh; Dirk A Kleinjan; Steven D Morley; John D West
Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium.
BMC developmental biology 2009;9():4.
2008: Natalie Dorà; Jingxing Ou; Romana Kucerova; Ida Parisi; John D West; J Martin Collinson
PAX6 dosage effects on corneal development, growth, and wound healing.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(5):1295-306.
2007: Clare A Everett; Margaret A Keighren; Jean H Flockhart; John D West
Evaluation of triploid<-->diploid and trisomy-3<-->diploid mouse chimeras as models for investigating how lineage restriction occurs in confined placental mosaicism.
Reproduction (Cambridge, England) 2007;134(6):799-809.
2007: Martine Manuel; Petrina A Georgala; Catherine B Carr; Simon A Chanas; Dirk A Kleinjan; Ben Martynoga; John O Mason; Michael Molinek; Jeni Pinson; Thomas Pratt; Jane C Quinn; Ian Simpson; David A Tyas; Veronica van Heyningen; John D West; David J Price
Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization.
Development (Cambridge, England) 2007;134(3):545-55.
2007: Jane C Quinn; Michael Molinek; Ben Martynoga; Paulette A Zaki; Andrea Faedo; Alessandro Bulfone; Robert Hevner; John D West; David J Price
Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism.
Developmental biology 2007;302(1):50-65.
2006: Thaya Ramaesh; Kanna Ramaesh; Rosemary Leask; Anthea Springbett; Simon C Riley; Baljean Dhillon; John D West
Increased apoptosis and abnormal wound-healing responses in the heterozygous Pax6+/- mouse cornea.
Investigative ophthalmology & visual science 2006;47(5):1911-7.
2005: Gillian E Mackay; John D West
Fate of tetraploid cells in 4n<-->2n chimeric mouse blastocysts.
Mechanisms of development 2005;122(12):1266-81.
2005: Thaya Ramaesh; Kanna Ramaesh; J Martin Collinson; Simon A Chanas; Baljean Dhillon; John D West
Developmental and cellular factors underlying corneal epithelial dysgenesis in the Pax6+/- mouse model of aniridia.
Experimental eye research 2005;81(2):224-35.
2005: Gillian E MacKay; Margaret A Keighren; Linda Wilson; Thomas Pratt; Jean H Flockhart; John O Mason; David J Price; John D West
Evaluation of the mouse TgTP6.3 tauGFP transgene as a lineage marker in chimeras.
Journal of anatomy 2005;206(1):79-92.
2004: Steven D Morley; S P Chang; Seong-Seng Tan; John D West
Validity of the 21-OH/LacZ transgenic mouse as a model for studying adrenocortical cell lineage.
Endocrine research 2004;30(4):513-9.
2004: Clare A Everett; Catherine A Auchincloss; Matthew H Kaufman; Catherine M Abbott; John D West
Genetic influences on ovulation of primary oocytes in LT/Sv strain mice.
Reproduction (Cambridge, England) 2004;128(5):565-71.
2004: Kanna Ramaesh; Thaya Ramaesh; John D West; Baljean Dhillon
Immunolocalisation of leukaemia inhibitory factor in the cornea.
Eye (London, England) 2004;18(10):1006-9.
2004: J Martin Collinson; Simon A Chanas; Robert E Hill; John D West
Corneal development, limbal stem cell function, and corneal epithelial cell migration in the Pax6(+/-) mouse.
Investigative ophthalmology & visual science 2004;45(4):1101-8.
2004: J Martin Collinson; Robert E Hill; John D West
Analysis of mouse eye development with chimeras and mosaics.
The International journal of developmental biology 2004;48(8-9):793-804.
2003: Supat Sinawat; Wei-Chih Hsaio; Jean H Flockhart; Matthew H Kaufman; John Keith; John D West
Fetal abnormalities produced after preimplantation exposure of mouse embryos to ammonium chloride.
Human reproduction (Oxford, England) 2003;18(10):2157-65.
2003: Roberta M James; Mark J Arends; Sarah J Plowman; David G Brooks; Colin G Miles; John D West; Charles E Patek
K-ras proto-oncogene exhibits tumor suppressor activity as its absence promotes tumorigenesis in murine teratomas.
Molecular cancer research : MCR 2003;1(11):820-5.
2003: Margaret A Keighren; Leah P Macfadyen; Alan S Hill; Charles E Patek; Evelyn E Telfer; John D West
Polyploid cells in the mouse ovary.
Journal of anatomy 2003;202(6):563-71.
2003: Thaya Ramaesh; J Martin Collinson; Kanna Ramaesh; Matthew H Kaufman; John D West; Baljean Dhillon
Corneal abnormalities in Pax6+/- small eye mice mimic human aniridia-related keratopathy.
Investigative ophthalmology & visual science 2003;44(5):1871-8.
2003: J Martin Collinson; Jane C Quinn; Robert E Hill; John D West
The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo.
Developmental biology 2003;255(2):303-12.
2003: Ana Talamillo; Jane C Quinn; J Martin Collinson; Damira Caric; David J Price; John D West; Robert E Hill
Pax6 regulates regional development and neuronal migration in the cerebral cortex.
Developmental biology 2003;255(1):151-63.
2002: Steven D Morley; Elizabeth A O'Donohoe; Katherine E Hughes; Catherine Irving; Sarah M Willis; Sarah Heasman; John D West
Mosaic patch patterns in chimeric and transgenic mice suggest that directional growth in the adrenal cortex begins in the perinatal period.
Endocrine research 2002;28(4):657-62.
2002: A Kelly; John D West
Survival and normal function of glycolysis-deficient mouse oocytes.
Reproduction (Cambridge, England) 2002;124(4):469-73.
2002: Thomas Pratt; Jane C Quinn; Ian Simpson; John D West; John O Mason; David J Price
Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(19):8523-31.
2002: J Martin Collinson; Lucy Morris; Alasdair I Reid; Thaya Ramaesh; Margaret A Keighren; Jean H Flockhart; Robert E Hill; Seong-Seng Tan; Kanna Ramaesh; Baljean Dhillon; John D West
Clonal analysis of patterns of growth, stem cell activity, and cell movement during the development and maintenance of the murine corneal epithelium.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;224(4):432-40.
2002: Annemarie Kelly; John D West
Developmental potential and survival of glycolysis-deficient cells in fetal mouse chimeras.
Genesis (New York, N.Y. : 2000) 2002;33(1):29-39.
2002: Tina Jaskoll; Yan-Min Zhou; Yang Chai; Helen P Makarenkova; J Martin Collinson; John D West; Mohammad K Hajihosseini; Jina Lee; Michael Melnick
Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice.
Cells, tissues, organs 2002;170(2-3):83-98.
2001: J Martin Collinson; Jane C Quinn; M A Buchanan; Matthew H Kaufman; S E Wedden; John D West; Robert E Hill
Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9688-93.
2001: PC Tang; John D West
Size regulation does not cause the composition of mouse chimaeras to become unbalanced.
The International journal of developmental biology 2001;45(3):583-90.
2000: PC Tang; John D West
The effects of embryo stage and cell number on the composition of mouse aggregation chimaeras.
Zygote (Cambridge, England) 2000;8(3):235-43.
2000: Clare A Everett; M H Stark; John D West; D Davidson; R A Baldock
Three-dimensional reconstruction of tetraploid<-->diploid chimaeric mouse blastocysts.
Journal of anatomy 2000;196 ( Pt 3)():341-6.
2000: J Martin Collinson; Robert E Hill; John D West
Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of the murine eye.
Development (Cambridge, England) 2000;127(5):945-56.
2000: A R Ellison; John D West; Norah Spears; A Murray; Clare A Everett; JO Bishop
Failure of founder transgenic male mice to transmit an attenuated HSV thymidine kinase transgene results from mosaicism and sperm competition.
Molecular reproduction and development 2000;55(3):249-55.
2000: PC Tang; W A Ritchie; I Wilmut; John D West
The effects of cell size and ploidy on cell allocation in mouse chimaeric blastocysts.
Zygote (Cambridge, England) 2000;8(1):33-43.
1999: Diana Borthwick; John D West; Margaret A Keighren; Jean H Flockhart; B A Innes; Julia R Dorin
Murine submucosal glands are clonally derived and show a cystic fibrosis gene-dependent distribution pattern.
American journal of respiratory cell and molecular biology 1999;20(6):1181-9.
1998: Clare A Everett; John D West
Evidence for selection against tetraploid cells in tetraploid<-->diploid mouse chimaeras before the late blastocyst stage.
Genetical research 1998;72(3):225-8.
1997: Jane C Quinn; John D West; Matthew H Kaufman
Genetic background effects on dental and other craniofacial abnormalities in homozygous small eye (Pax6Sey/Pax6Sey) mice.
Anatomy and embryology 1997;196(4):311-21.
1997: John D West; B A Hodson; Margaret A Keighren
Quantitative and spatial information on the composition of chimaeric fetal mouse eyes from single histological sections.
Development, growth & differentiation 1997;39(3):305-17.
1996: A Kelly; John D West
Genetic evidence that glycolysis is necessary for gastrulation in the mouse.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;207(3):300-8.
1996: John D West; Margaret A Keighren; J H Flockhart
A quantitative test for developmental neutrality of a transgenic lineage marker in mouse chimaeras.
Genetical research 1996;67(2):135-46.
1996: C A Everett; John D West
The influence of ploidy on the distribution of cells in chimaeric mouse blastocysts.
Zygote (Cambridge, England) 1996;4(1):59-66.
1995: John D West; J H Flockhart; Margaret A Keighren
Biochemical evidence for cell fusion in placentas of mouse aggregation chimeras.
Developmental biology 1995;168(1):76-85.
1995: John D West; J H Flockhart; adrien kissenpfennig
A maternal genetic effect on the composition of mouse aggregation chimaeras.
Genetical research 1995;65(1):29-40.
1995: R M James; A H Klerkx; Margaret A Keighren; J H Flockhart; John D West
Restricted distribution of tetraploid cells in mouse tetraploid<==>diploid chimaeras.
Developmental biology 1995;167(1):213-26.
1994: R M James; John D West
A chimaeric animal model for confined placental mosaicism.
Human genetics 1994;93(5):603-4.
1994: John D West; J H Flockhart
Genotypically unbalanced diploid<==>diploid foetal mouse chimaeras: possible relevance to human confined mosaicism.
Genetical research 1994;63(2):87-99.
1994: Frank D Johnstone; John D West; J Steel; David B Whitehouse; G A Drago; Ian A Greer; Robin J Prescott
Lack of association between maternal phosphoglucomutase-1 phenotype and fetal macrosomia in diabetic pregnancy.
British journal of obstetrics and gynaecology 1994;101(3):239-45.
1993: John D West; S Webb; Matthew H Kaufman
Inheritance of a meiotic abnormality that causes the ovulation of primary oocytes and the production of digynic triploid mice.
Genetical research 1993;62(3):183-93.
1993: Frank D Johnstone; John D West; Robin J Prescott; J M Steel; J A Flockhart; Ian A Greer; G A Drago; David B Whitehouse
Fetal growth, gestation length and phosphoglucomutase-1 phenotype.
Disease markers 1993;11(5-6):251-62.
1993: John D West
A genetically defined animal model of anembryonic pregnancy.
Human reproduction (Oxford, England) 1993;8(8):1316-23.
1993: Margaret A Keighren; John D West
Analysis of cell ploidy in histological sections of mouse tissues by DNA-DNA in situ hybridization with digoxigenin-labelled probes.
The Histochemical journal 1993;25(1):30-44.
1992: R M James; Matthew H Kaufman; S Webb; John D West
Electrofusion of mouse embryos results in uniform tetraploidy and not tetraploid/diploid mosaicism.
Genetical research 1992;60(3):185-94.
1991: John D West; J D Ansell; J H Flockhart
Expression of glucose phosphate isomerase in interspecific hybrid (Mus musculus x Mus caroli) mouse embryos.
Developmental genetics 1991;12(6):403-14.
1990: John D West; J H Flockhart; J Peters; S T Ball
Death of mouse embryos that lack a functional gene for glucose phosphate isomerase.
Genetical research 1990;56(2-3):223-36.
1990: P M Ellis; John D West; K M West; R S Murray; M C Coyle
Relevance to prenatal diagnosis of the identification of a human Y/autosome translocation by Y-chromosome-specific in situ hybridisation.
Molecular reproduction and development 1990;25(1):37-41.
1989: John D West; J H Flockhart
Genetic differences in glucose phosphate isomerase activity among mouse embryos.
Development (Cambridge, England) 1989;107(3):465-72.
1989: John D West; J H Flockhart
Non-additive inheritance of glucose phosphate isomerase activity in mice heterozygous at the Gpi-1s structural locus.
Genetical research 1989;54(1):27-35.
1989: John D West; J H Flockhart; R R Angell; Stephen G Hillier; S S Thatcher; Anna Glasier; M W Rodger; David T Baird
Glucose phosphate isomerase activity in mouse and human eggs and pre-embryos.
Human reproduction (Oxford, England) 1989;4(1):82-5.
1989: John D West
The use of DNA probes in preimplantation and prenatal diagnosis.
Molecular reproduction and development 1989;1(2):138-45.
1989: John D West; C M Gosden; JR Gosden; K M West; Z Davidson; C Davidson; K H Nicolaides
Sexing the human fetus and identification of polyploid nuclei by DNA-DNA in situ hybridisation in interphase nuclei.
Molecular reproduction and development 1989;1(2):129-37.
1989: John D West; K M West; R John Aitken
Detection of Y-bearing spermatozoa by DNA-DNA in situ hybridisation.
Molecular reproduction and development 1989;1(3):201-7.
1988: S S Thatcher; R E Angell; John D West; Anna Glasier; Rodney W Kelly; Stephen G Hillier; David T Baird
Effects of preovulatory tamoxifen in regularly cycling women on folliculogenesis, oocyte recovery and luteal function.
Human reproduction (Oxford, England) 1988;3(8):935-8.
1988: John D West; JR Gosden; R R Angell; K M West; Anna Glasier; S S Thatcher; David T Baird
Sexing whole human pre-embryos by in-situ hybridization with a Y-chromosome specific DNA probe.
Human reproduction (Oxford, England) 1988;3(8):1010-9.
1988: R R Angell; Stephen G Hillier; John D West; Anna Glasier; M W Rodger; David T Baird
Chromosome anomalies in early human embryos.
Journal of reproduction and fertility. Supplement 1988;36():73-81.
1987: R R Angell; A T Sumner; John D West; S S Thatcher; Anna Glasier; David T Baird
Post-fertilization polyploidy in human preimplantation embryos fertilized in-vitro.
Human reproduction (Oxford, England) 1987;2(8):721-7.
1987: John D West; Rosemary Leask; J H Flockhart; G Fisher
High activity of an unstable form of glucose phosphate isomerase in the mouse.
Biochemical genetics 1987;25(7-8):543-61.
1987: John D West; JR Gosden; R R Angell; N D Hastie; S S Thatcher; Anna Glasier; David T Baird
Sexing the human pre-embryo by DNA-DNA in-situ hybridisation.
Lancet 1987;1(8546):1345-7.
1986: John D West; Rosemary Leask; J F Green
Quantification of the transition from oocyte-coded to embryo-coded glucose phosphate isomerase in mouse embryos.
Journal of embryology and experimental morphology 1986;97():225-37.
1983: John D West; J F Green
The transition from oocyte-coded to embryo-coded glucose phosphate isomerase in the early mouse embryo.
Journal of embryology and experimental morphology 1983;78():127-40.