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Stephen West

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Escherichia coli

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TOP 3
Özlem Yüce; Stephen C West
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.
Joao Matos; J Mark Skehel; Miguel G Blanco; Sarah Maslen; Stephen C West
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis.
Haley D M Wyatt; Stephen C West; Tara L Beattie
InTERTpreting telomerase structure and function.

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All Publications

2013: Özlem Yüce; Stephen C West
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.
Molecular and cellular biology 2013;33(2):406-17.
2011: Joao Matos; J Mark Skehel; Miguel G Blanco; Sarah Maslen; Stephen C West
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis.
Cell 2011;147(1):158-72.
2010: Haley D M Wyatt; Stephen C West; Tara L Beattie
InTERTpreting telomerase structure and function.
Nucleic acids research 2010;38(17):5609-22.
2010: Ulrich Rass; Sarah A Compton; Joao Matos; Martin R Singleton; Stephen C Y Ip; Miguel G Blanco; Jack D Griffith; Stephen C West
Mechanism of Holliday junction resolution by the human GEN1 protein.
Genes & development 2010;24(14):1559-69.
2010: Miguel G Blanco; Joao Matos; Ulrich Rass; Stephen C Y Ip; Stephen C West
Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae.
DNA repair 2010;9(4):394-402.
2010: Alexander Lorenz; Stephen C West; Matthew C Whitby
The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant.
Nucleic acids research 2010;38(6):1866-73.
2010: Jillian L Youds; David G Mets; Michael J McIlwraith; Julie S Martin; Jordan D Ward; Nigel J ONeil; Ann M Rose; Stephen C West; Barbara J Meyer; Simon J Boulton
RTEL-1 enforces meiotic crossover interference and homeostasis.
Science (New York, N.Y.) 2010;327(5970):1254-8.
2009: Andrew Deans; Stephen C West
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia.
Molecular cell 2009;36(6):943-53.
2008: Michael J McIlwraith; Stephen C West
DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair.
Molecular cell 2008;29(4):510-6.
2008: Ivan Ahel; Dragana Ahel; Takahiro Matsusaka; Allison J Clark; Jonathon Pines; Simon J Boulton; Stephen C West
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins.
Nature 2008;451(7174):81-5.
2008: Alberto Ciccia; Neil McDonald; Stephen C West
Structural and functional relationships of the XPF/MUS81 family of proteins.
Annual review of biochemistry 2008;77():259-87.
2007: Tina Thorslund; Stephen C West
BRCA2: a universal recombinase regulator.
Oncogene 2007;26(56):7720-30.
2007: Ulrich Rass; Ivan Ahel; Stephen C West
Defective DNA repair and neurodegenerative disease.
Cell 2007;130(6):991-1004.
2007: Tina Thorslund; fumiko esashi; Stephen C West
Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1.
The EMBO journal 2007;26(12):2915-22.
2007: fumiko esashi; Vitold E Galkin; Xiong Yu; Edward H Egelman; Stephen C West
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.
Nature structural & molecular biology 2007;14(6):468-74.
2007: Ulrich Rass; Ivan Ahel; Stephen C West
Actions of aprataxin in multiple DNA repair pathways.
The Journal of biological chemistry 2007;282(13):9469-74.
2007: Alberto Ciccia; Chen Ling; Rachel Coulthard; Zhijiang Yan; Yutong Xue; Amom Ruhikanta Meetei; El Houari Laghmani; Hans Joenje; Neil McDonald; Johan P de Winter; Weidong Wang; Stephen C West
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.
Molecular cell 2007;25(3):331-43.
2007: Yilun Liu; Madalena Tarsounas; Paul O'Regan; Stephen C West
Role of RAD51C and XRCC3 in genetic recombination and DNA repair.
The Journal of biological chemistry 2007;282(3):1973-9.
2006: Ivan Ahel; Ulrich Rass; Sherif F El-Khamisy; Sachin Katyal; Paula M Clements; Peter J McKinnon; Keith W Caldecott; Stephen C West
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.
Nature 2006;443(7112):713-6.
2006: Amélie Rodrigue; Matthieu Lafrance; Marie-Christine Gauthier; Darin McDonald; Michael Hendzel; Stephen C West; Maria Jasin; Jean-Yves Masson
Interplay between human DNA repair proteins at a unique double-strand break in vivo.
The EMBO journal 2006;25(1):222-31.
2006: Ulrich Rass; Stephen C West
Synthetic junctions as tools to identify and characterize Holliday junction resolvases.
Methods in enzymology 2006;408():485-501.
2005: Michael J McIlwraith; Michael J Mcllwraith; Alexandra Vaisman; Yilun Liu; Ellen Fanning; Roger Woodgate; Stephen C West
Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination.
Molecular cell 2005;20(5):783-92.
2005: Vitold E Galkin; fumiko esashi; Xiong Yu; Shixin Yang; Stephen C West; Edward H Egelman
BRCA2 BRC motifs bind RAD51-DNA filaments.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(24):8537-42.
2005: Madalena Tarsounas; Stephen C West
Recombination at mammalian telomeres: an alternative mechanism for telomere protection and elongation.
Cell cycle (Georgetown, Tex.) 2005;4(5):672-4.
2005: fumiko esashi; Nicole Christ; Julian Gannon; Yilun Liu; Tim Hunt; Maria Jasin; Stephen C West
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair.
Nature 2005;434(7033):598-604.
2004: Yilun Liu; Stephen C West
Happy Hollidays: 40th anniversary of the Holliday junction.
Nature reviews. Molecular cell biology 2004;5(11):937-44.
2004: Shobbir Hussain; James B Wilson; Annette L Medhurst; James Hejna; Emily Witt; Sahana Ananth; Adelina Davies; Jean-Yves Masson; Robb Moses; Stephen C West; Johan P de Winter; Alan Ashworth; Nigel Jones; Christopher G Mathew
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways.
Human molecular genetics 2004;13(12):1241-8.
2004: Madalena Tarsounas; Purificacíon Muñoz; Andreas Claas; Phillip G Smiraldo; Douglas L Pittman; María A Blasco; Stephen C West
Telomere maintenance requires the RAD51D recombination/repair protein.
Cell 2004;117(3):337-47.
2004: Yilun Liu; Andrzej Stasiak; Jean-Yves Masson; Michael J McIlwraith; Andrzej Stasiak; Stephen C West
Conformational changes modulate the activity of human RAD51 protein.
Journal of molecular biology 2004;337(4):817-27.
2004: Madalena Tarsounas; Adelina A Davies; Stephen C West
RAD51 localization and activation following DNA damage.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1441):87-93.
2004: Yilun Liu; Jean-Yves Masson; Rajvee Shah; Paul O'Regan; Stephen C West
RAD51C is required for Holliday junction processing in mammalian cells.
Science (New York, N.Y.) 2004;303(5655):243-6.
2004: Angelos Constantinou; Stephen C West
Holliday junction branch migration and resolution assays.
Methods in molecular biology (Clifton, N.J.) 2004;262():239-53.
2003: Jacinth Abraham; Bénédicte Lemmers; M Prakash Hande; Mary Ellen Moynahan; Charly Chahwan; Alberto Ciccia; Jeroen Essers; Katsuhiro Hanada; Richard Chahwan; Aik Kia Khaw; Peter McPherson; Amro Shehabeldin; Rob Laister; Cheryl H Arrowsmith; Roland Kanaar; Stephen C West; Maria Jasin; Raza Hakem
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells.
The EMBO journal 2003;22(22):6137-47.
2003: Alberto Ciccia; Angelos Constantinou; Stephen C West
Identification and characterization of the human mus81-eme1 endonuclease.
The Journal of biological chemistry 2003;278(27):25172-8.
2003: Stephen C West
Molecular views of recombination proteins and their control.
Nature reviews. Molecular cell biology 2003;4(6):435-45.
2003: Judith Henry-Mowatt; Dean Jackson; Jean-Yves Masson; Penny A Johnson; Paula M Clements; Fiona E Benson; Larry H Thompson; Shunichi Takeda; Stephen C West; Keith W Caldecott
XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes.
Molecular cell 2003;11(4):1109-17.
2003: Yan Dai; Boris Kysela; Leslyn Hanakahi; Kostas Manolis; Enriqueta Riballo; Markus Stumm; T O Harville; Stephen C West; Marjorie A Oettinger; Penny A Jeggo
Nonhomologous end joining and V(D)J recombination require an additional factor.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2462-7.
2003: Madalena Tarsounas; Derek Davies; Stephen C West
BRCA2-dependent and independent formation of RAD51 nuclear foci.
Oncogene 2003;22(8):1115-23.
2003: Stephen C West
Cross-links between Fanconi anaemia and BRCA2.
DNA repair 2003;2(2):231-4.
2002: Angelos Constantinou; Xiao-Bo Chen; Clare H McGowan; Stephen C West
Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities.
The EMBO journal 2002;21(20):5577-85.
2002: Claire Chappell; Leslyn Hanakahi; Feridoun Karimi-Busheri; Michael Weinfeld; Stephen C West
Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining.
The EMBO journal 2002;21(11):2827-32.
2002: Catherine A French; Jean-Yves Masson; Carol S Griffin; Paul O'Regan; Stephen C West; John Thacker
Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability.
The Journal of biological chemistry 2002;277(22):19322-30.
2002: Leslyn Hanakahi; Stephen C West
Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK.
The EMBO journal 2002;21(8):2038-44.
2002: Yilun Liu; Stephen C West
Distinct functions of BRCA1 and BRCA2 in double-strand break repair.
Breast cancer research : BCR 2002;4(1):9-13.
2001: Jean-Yves Masson; Madalena Tarsounas; A Z Stasiak; Andrzej Stasiak; R Shah; Michael J McIlwraith; Fiona E Benson; Stephen C West
Identification and purification of two distinct complexes containing the five RAD51 paralogs.
Genes & development 2001;15(24):3296-307.
2001: Michael J McIlwraith; David Hall; A Z Stasiak; Andrzej Stasiak; Dale B Wigley; Stephen C West
RadA protein from Archaeoglobus fulgidus forms rings, nucleoprotein filaments and catalyses homologous recombination.
Nucleic acids research 2001;29(22):4509-17.
2001: E Van Dyck; A Z Stasiak; Andrzej Stasiak; Stephen C West
Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing.
EMBO reports 2001;2(10):905-9.
2001: Jean-Yves Masson; A Z Stasiak; Andrzej Stasiak; Fiona E Benson; Stephen C West
Complex formation by the human RAD51C and XRCC3 recombination repair proteins.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8440-6.
2001: Xiong Yu; Steven Jacobs; Stephen C West; T Ogawa; Edward H Egelman
Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8419-24.
2001: Adelina A Davies; Jean-Yves Masson; Michael J McIlwraith; A Z Stasiak; Andrzej Stasiak; A R Venkitaraman; Stephen C West
Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.
Molecular cell 2001;7(2):273-82.
2001: Jean-Yves Masson; Stephen C West
The Rad51 and Dmc1 recombinases: a non-identical twin relationship.
Trends in biochemical sciences 2001;26(2):131-6.
2001: Angelos Constantinou; Adelina A Davies; Stephen C West
Branch migration and Holliday junction resolution catalyzed by activities from mammalian cells.
Cell 2001;104(2):259-68.
2001: Michael J McIlwraith; Stephen C West
The efficiency of strand invasion by Escherichia coli RecA is dependent upon the length and polarity of ssDNA tails.
Journal of molecular biology 2001;305(1):23-31.
2000: Michael J McIlwraith; E Van Dyck; Jean-Yves Masson; A Z Stasiak; Andrzej Stasiak; Stephen C West
Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins.
Journal of molecular biology 2000;304(2):151-64.
2000: Leslyn Hanakahi; M Bartlet-Jones; Claire Chappell; Darryl Pappin; Stephen C West
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair.
Cell 2000;102(6):721-9.
2000: J Arenas-Licea; Alain van Gool; Anthony Keeley; A Davies; Stephen C West; Irina R Tsaneva
Functional interactions of Mycobacterium leprae RuvA with Escherichia coli RuvB and RuvC on holliday junctions.
Journal of molecular biology 2000;301(4):839-50.
2000: AK Eggleston; Stephen C West
Cleavage of holliday junctions by the Escherichia coli RuvABC complex.
The Journal of biological chemistry 2000;275(34):26467-76.
2000: C A Parsons; P Baumann; E Van Dyck; Stephen C West
Precise binding of single-stranded DNA termini by human RAD52 protein.
The EMBO journal 2000;19(15):4175-81.
2000: A Constantinou; Madalena Tarsounas; JK Karow; Robert M Brosh; Vilhelm A Bohr; Ian D Hickson; Stephen C West
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.
EMBO reports 2000;1(1):80-4.
2000: JK Karow; A Constantinou; Ji-Liang Li; Stephen C West; Ian D Hickson
The Bloom's syndrome gene product promotes branch migration of holliday junctions.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6504-8.
2000: VP Yu; M Koehler; C Steinlein; M Schmid; Leslyn Hanakahi; Alain van Gool; Stephen C West; Ashok R Venkitaraman
Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation.
Genes & development 2000;14(11):1400-6.
2000: A Z Stasiak; Eric Larquet; Andrzej Stasiak; S Müller; A Engel; E Van Dyck; Stephen C West; Edward H Egelman
The human Rad52 protein exists as a heptameric ring.
Current biology : CB 2000;10(6):337-40.
2000: H George; Isao Kuraoka; D A Nauman; WR Kobertz; Richard D Wood; Stephen C West
RuvAB-mediated branch migration does not involve extensive DNA opening within the RuvB hexamer.
Current biology : CB 2000;10(2):103-6.
2000: Stephen C West; Claire Chappell; Leslyn Hanakahi; Jean-Yves Masson; Michael J McIlwraith; E Van Dyck
Double-strand break repair in human cells.
Cold Spring Harbor symposia on quantitative biology 2000;65():315-21.
1999: Jean-Yves Masson; Adelina A Davies; NM Hajibagheri; E Van Dyck; Fiona E Benson; A Z Stasiak; Andrzej Stasiak; Stephen C West
The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.
The EMBO journal 1999;18(22):6552-60.
1999: H George; C Mézard; Andrzej Stasiak; Stephen C West
Helicase-defective RuvB(D113E) promotes RuvAB-mediated branch migration in vitro.
Journal of molecular biology 1999;293(3):505-19.
1999: S I Passy; X Yu; Z Li; C M Radding; Jean-Yves Masson; Stephen C West; E H Egelman
Human Dmc1 protein binds DNA as an octameric ring.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10684-8.
1999: P Baumann; Stephen C West
Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52.
Journal of molecular biology 1999;291(2):363-74.
1999: Alain van Gool; NM Hajibagheri; Andrzej Stasiak; Stephen C West
Assembly of the Escherichia coli RuvABC resolvasome directs the orientation of holliday junction resolution.
Genes & development 1999;13(14):1861-70.
1999: E Van Dyck; A Z Stasiak; Andrzej Stasiak; Stephen C West
Binding of double-strand breaks in DNA by human Rad52 protein.
Nature 1999;398(6729):728-31.
1999: C Mézard; H George; Adelina A Davies; Alain van Gool; D Zerbib; Andrzej Stasiak; Stephen C West
Escherichia coli RuvBL268S: a mutant RuvB protein that exhibits wild-type activities in vitro but confers a UV-sensitive ruv phenotype in vivo.
Nucleic acids research 1999;27(5):1275-82.
1998: E Van Dyck; NM Hajibagheri; Andrzej Stasiak; Stephen C West
Visualisation of human rad52 protein and its complexes with hRad51 and DNA.
Journal of molecular biology 1998;284(4):1027-38.
1998: P Baumann; Stephen C West
DNA end-joining catalyzed by human cell-free extracts.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14066-70.
1998: Stephen C West
RuvA gets X-rayed on holliday.
Cell 1998;94(6):699-701.
1998: D Zerbib; C Mézard; H George; Stephen C West
Coordinated actions of RuvABC in Holliday junction processing.
Journal of molecular biology 1998;281(4):621-30.
1998: Adelina A Davies; Stephen C West
Formation of RuvABC-Holliday junction complexes in vitro.
Current biology : CB 1998;8(12):725-7.
1998: Alain van Gool; R Shah; C Mézard; Stephen C West
Functional interactions between the holliday junction resolvase and the branch migration motor of Escherichia coli.
The EMBO journal 1998;17(6):1838-45.
1998: Fiona E Benson; P Baumann; Stephen C West
Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.
Nature 1998;391(6665):401-4.
1997: AK Eggleston; Stephen C West
Recombination initiation: easy as A, B, C, D... chi?
Current biology : CB 1997;7(12):R745-9.
1997: C Mézard; Adelina A Davies; Andrzej Stasiak; Stephen C West
Biochemical properties of RuvBD113N: a mutation in helicase motif II of the RuvB hexamer affects DNA binding and ATPase activities.
Journal of molecular biology 1997;271(5):704-17.
1997: AL Barlow; Fiona E Benson; Stephen C West; Maj A Hultén
Distribution of the Rad51 recombinase in human and mouse spermatocytes.
The EMBO journal 1997;16(17):5207-15.
1997: P Baumann; Stephen C West
The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A.
The EMBO journal 1997;16(17):5198-206.
1997: P Baumann; Fiona E Benson; NM Hajibagheri; Stephen C West
Purification of human Rad51 protein by selective spermidine precipitation.
Mutation research 1997;384(2):65-72.
1997: D Zerbib; Sean D Colloms; David J Sherratt; Stephen C West
Effect of DNA topology on Holliday junction resolution by Escherichia coli RuvC and bacteriophage T7 endonuclease I.
Journal of molecular biology 1997;270(5):663-73.
1997: AK Eggleston; A H Mitchell; Stephen C West
In vitro reconstitution of the late steps of genetic recombination in E. coli.
Cell 1997;89(4):607-17.
1997: R Shah; R Cosstick; Stephen C West
The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts.
The EMBO journal 1997;16(6):1464-72.
1997: Stephen C West
Processing of recombination intermediates by the RuvABC proteins.
Annual review of genetics 1997;31():213-44.
1996: R J Bennett; Stephen C West
Resolution of Holliday junctions in genetic recombination: RuvC protein nicks DNA at the point of strand exchange.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12217-22.
1996: A H Mitchell; Stephen C West
Role of RuvA in branch migration reactions catalyzed by the RuvA and RuvB proteins of Escherichia coli.
The Journal of biological chemistry 1996;271(32):19497-502.
1996: Stephen C West
DNA helicases: new breeds of translocating motors and molecular pumps.
Cell 1996;86(2):177-80.
1996: K Hiom; I R Tsaneva; Stephen C West
The directionality of RuvAB-mediated branch migration: in vitro studies with three-armed junctions.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(5):443-51.
1996: Stephen C West
The RuvABC proteins and Holliday junction processing in Escherichia coli.
Journal of bacteriology 1996;178(5):1237-41.
1995: C A Parsons; Andrzej Stasiak; Stephen C West
The E.coli RuvAB proteins branch migrate Holliday junctions through heterologous DNA sequences in a reaction facilitated by SSB.
The EMBO journal 1995;14(22):5736-44.
1995: D E Adams; Stephen C West
Relaxing and unwinding on Holliday: DNA helicase-mediated branch migration.
Mutation research 1995;337(3):149-59.
1995: Adelina A Davies; E C Friedberg; Alan E Tomkinson; Richard D Wood; Stephen C West
Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination.
The Journal of biological chemistry 1995;270(42):24638-41.
1995: R J Bennett; Stephen C West
Structural analysis of the RuvC-Holliday junction complex reveals an unfolded junction.
Journal of molecular biology 1995;252(2):213-26.
1995: R J Bennett; Stephen C West
RuvC protein resolves Holliday junctions via cleavage of the continuous (noncrossover) strands.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5635-9.
1995: D E Adams; Stephen C West
Unwinding of closed circular DNA by the Escherichia coli RuvA and RuvB recombination/repair proteins.
Journal of molecular biology 1995;247(3):404-17.
1995: C A Parsons; Andrzej Stasiak; R J Bennett; Stephen C West
Structure of a multisubunit complex that promotes DNA branch migration.
Nature 1995;374(6520):375-8.
1995: K Hiom; Stephen C West
Branch migration during homologous recombination: assembly of a RuvAB-Holliday junction complex in vitro.
Cell 1995;80(5):787-93.
1994: R Shah; R J Bennett; Stephen C West
Genetic recombination in E. coli: RuvC protein cleaves Holliday junctions at resolution hotspots in vitro.
Cell 1994;79(5):853-64.
1994: Fiona E Benson; Andrzej Stasiak; Stephen C West
Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA.
The EMBO journal 1994;13(23):5764-71.
1994: A H Mitchell; Stephen C West
Hexameric rings of Escherichia coli RuvB protein. Cooperative assembly, processivity and ATPase activity.
Journal of molecular biology 1994;243(2):208-15.
1994: I R Tsaneva; Stephen C West
Targeted versus non-targeted DNA helicase activity of the RuvA and RuvB proteins of Escherichia coli.
The Journal of biological chemistry 1994;269(42):26552-8.
1994: A O'Donovan; Adelina A Davies; Jonathan G Moggs; Stephen C West; Richard D Wood
XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair.
Nature 1994;371(6496):432-5.
1994: Stephen C West
Processing of Holliday junctions by RuvABC--an overview.
Annals of the New York Academy of Sciences 1994;726():156-63; discussion 163-4.
1994: R Shah; R J Bennett; Stephen C West
Activation of RuvC Holliday junction resolvase in vitro.
Nucleic acids research 1994;22(13):2490-7.
1994: B Müller; Stephen C West
Processing of Holliday junctions by the Escherichia coli RuvA, RuvB, RuvC and RecG proteins.
Experientia 1994;50(3):216-22.
1994: H Hyde; Adelina A Davies; Fiona E Benson; Stephen C West
Resolution of recombination intermediates by a mammalian activity functionally analogous to Escherichia coli RuvC resolvase.
The Journal of biological chemistry 1994;269(7):5202-9.
1994: Fiona E Benson; Stephen C West
Substrate specificity of the Escherichia coli RuvC protein. Resolution of three- and four-stranded recombination intermediates.
The Journal of biological chemistry 1994;269(7):5195-201.
1994: H J Dunderdale; Gary Sharples; Robert G Lloyd; Stephen C West
Cloning, overexpression, purification, and characterization of the Escherichia coli RuvC Holliday junction resolvase.
The Journal of biological chemistry 1994;269(7):5187-94.
1994: Stephen C West
The processing of recombination intermediates: mechanistic insights from studies of bacterial proteins.
Cell 1994;76(1):9-15.
1994: B Müller; Stephen C West
An assay for in vitro recombination between duplex DNA molecules.
Methods in molecular biology (Clifton, N.J.) 1994;30():413-23.
1993: B Müller; I R Tsaneva; Stephen C West
Branch migration of Holliday junctions promoted by the Escherichia coli RuvA and RuvB proteins. II. Interaction of RuvB with DNA.
The Journal of biological chemistry 1993;268(23):17185-9.
1993: B Müller; I R Tsaneva; Stephen C West
Branch migration of Holliday junctions promoted by the Escherichia coli RuvA and RuvB proteins. I. Comparison of RuvAB- and RuvB-mediated reactions.
The Journal of biological chemistry 1993;268(23):17179-84.
1993: C A Parsons; Stephen C West
Formation of a RuvAB-Holliday junction complex in vitro.
Journal of molecular biology 1993;232(2):397-405.
1993: I R Tsaneva; B Müller; Stephen C West
RuvA and RuvB proteins of Escherichia coli exhibit DNA helicase activity in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1315-9.
1993: Stephen C West; I R Tsaneva; K Hiom; Fiona E Benson
Late steps in genetic recombination: branch migration and Holliday junction resolution by RuvA, RuvB, and RuvC proteins.
Cold Spring Harbor symposia on quantitative biology 1993;58():525-31.
1992: I R Tsaneva; G Illing; Robert G Lloyd; Stephen C West
Purification and properties of the RuvA and RuvB proteins of Escherichia coli.
Molecular & general genetics : MGG 1992;235(1):1-10.
1992: Stephen C West; B Connolly
Biological roles of the Escherichia coli RuvA, RuvB and RuvC proteins revealed.
Molecular microbiology 1992;6(19):2755-9.
1992: B Müller; I Burdett; Stephen C West
Unusual stability of recombination intermediates made by Escherichia coli RecA protein.
The EMBO journal 1992;11(7):2685-93.
1992: I R Tsaneva; B Müller; Stephen C West
ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E. coli.
Cell 1992;69(7):1171-80.
1992: C A Parsons; I Tsaneva; Robert G Lloyd; Stephen C West
Interaction of Escherichia coli RuvA and RuvB proteins with synthetic Holliday junctions.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5452-6.
1992: Stephen C West
Enzymes and molecular mechanisms of genetic recombination.
Annual review of biochemistry 1992;61():603-40.
1991: H J Dunderdale; Fiona E Benson; C A Parsons; Gary Sharples; Robert G Lloyd; Stephen C West
Formation and resolution of recombination intermediates by E. coli RecA and RuvC proteins.
Nature 1991;354(6354):506-10.
1991: B Müller; P E Boehmer; Peter T Emmerson; Stephen C West
Action of RecBCD enzyme on Holliday structures made by RecA.
The Journal of biological chemistry 1991;266(28):19028-33.
1991: B Connolly; C A Parsons; Fiona E Benson; H J Dunderdale; Gary Sharples; Robert G Lloyd; Stephen C West
Resolution of Holliday junctions in vitro requires the Escherichia coli ruvC gene product.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6063-7.
1991: Stephen C West
Three-stranded DNA helices as intermediates in genetic recombination.
BioEssays : news and reviews in molecular, cellular and developmental biology 1991;13(1):37-8.
1990: B Connolly; Stephen C West
Genetic recombination in Escherichia coli: Holliday junctions made by RecA protein are resolved by fractionated cell-free extracts.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8476-80.
1990: B Müller; C Jones; Stephen C West
T7 endonuclease I resolves Holliday junctions formed in vitro by RecA protein.
Nucleic acids research 1990;18(19):5633-6.
1990: K M Elborough; Stephen C West
Resolution of synthetic Holliday junctions in DNA by an endonuclease activity from calf thymus.
The EMBO journal 1990;9(9):2931-6.
1990: C A Parsons; Stephen C West
Specificity of binding to four-way junctions in DNA by bacteriophage T7 endonuclease I.
Nucleic acids research 1990;18(15):4377-84.
1990: E C Conley; Stephen C West
Underwinding of DNA associated with duplex-duplex pairing by RecA protein.
The Journal of biological chemistry 1990;265(17):10156-63.
1990: C A Parsons; B Kemper; Stephen C West
Interaction of a four-way junction in DNA with T4 endonuclease VII.
The Journal of biological chemistry 1990;265(16):9285-9.
1990: S M Picksley; C A Parsons; B Kemper; Stephen C West
Cleavage specificity of bacteriophage T4 endonuclease VII and bacteriophage T7 endonuclease I on synthetic branch migratable Holliday junctions.
Journal of molecular biology 1990;212(4):723-35.
1990: Stephen C West
Processing of recombination intermediates in vitro.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(4):151-4.
1990: B Müller; C Jones; B Kemper; Stephen C West
Enzymatic formation and resolution of Holliday junctions in vitro.
Cell 1990;60(2):329-36.
1989: E C Conley; Stephen C West
Homologous pairing and the formation of nascent synaptic intermediates between regions of duplex DNA by RecA protein.
Cell 1989;56(6):987-95.
1989: C A Parsons; A I Murchie; D M Lilley; Stephen C West
Resolution of model Holliday junctions by yeast endonuclease: effect of DNA structure and sequence.
The EMBO journal 1989;8(1):239-46.
1988: K M Elborough; Stephen C West
Specific binding of cruciform DNA structures by a protein from human extracts.
Nucleic acids research 1988;16(9):3603-16.
1988: C A Parsons; Stephen C West
Resolution of model Holliday junctions by yeast endonuclease is dependent upon homologous DNA sequences.
Cell 1988;52(4):621-9.
1987: Stephen C West; C A Parsons; S M Picksley
Purification and properties of a nuclease from Saccharomyces cerevisiae that cleaves DNA at cruciform junctions.
The Journal of biological chemistry 1987;262(26):12752-8.