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Lori Westover

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Brian C Shook; Nathaniel Wallace; Aihua Wang; Lori Westover; Vernon C Alford; Mark Ault; J Kent Barbay; Karen Carroll; Devraj Chakravarty; Jeffrey J Crooke; Lisa Lampron; Kristi Leonard; Mark T Powell; Stefanie Rassnick; Kenneth Rhodes; Robert H Scannevin; Paul F Jackson
Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists.
Brian C Shook; Nathaniel Wallace; Aihua Wang; Kenneth M Wells; Lori Westover; Scott Youells; Vernon C Alford; Mark Ault; J Kent Barbay; Derek A Beauchamp; Shawn Branum; Karen Carroll; Devraj Chakravarty; Jeffrey J Crooke; Sandra Damon; Lisa Lampron; Kristi Leonard; Xun Li; Heng-Keang Lim; Mark T Powell; Stefanie Rassnick; Kenneth Rhodes; Ronald Russell; Robert H Scannevin; Paul F Jackson
Design and characterization of optimized adenosine A₂A/A₁ receptor antagonists for the treatment of Parkinson's disease.
Brian C Shook; Stefanie Rassnick; Melville C Osborne; Scott Davis; Lori Westover; Jamie Boulet; Daniel Hall; Kenneth C Rupert; Geoffrey R Heintzelman; Kristin Hansen; Devraj Chakravarty; James L Bullington; Ronald Russell; Shawn Branum; Kenneth M Wells; Sandra Damon; Scott Youells; Xun Li; Derek A Beauchamp; David Palmer; Mayra Reyes; Keith T Demarest; Yuting Tang; Kenneth Rhodes; Paul F Jackson
In vivo characterization of a dual adenosine A2A/A1 receptor antagonist in animal models of Parkinson's disease.

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All Publications

2013: Brian C Shook; Nathaniel Wallace; Aihua Wang; Lori Westover; Vernon C Alford; Mark Ault; J Kent Barbay; Karen Carroll; Devraj Chakravarty; Jeffrey J Crooke; Lisa Lampron; Kristi Leonard; Mark T Powell; Stefanie Rassnick; Kenneth Rhodes; Robert H Scannevin; Paul F Jackson
Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists.
Bioorganic & medicinal chemistry letters 2013;23(9):2688-91.
2012: Brian C Shook; Nathaniel Wallace; Aihua Wang; Kenneth M Wells; Lori Westover; Scott Youells; Vernon C Alford; Mark Ault; J Kent Barbay; Derek A Beauchamp; Shawn Branum; Karen Carroll; Devraj Chakravarty; Jeffrey J Crooke; Sandra Damon; Lisa Lampron; Kristi Leonard; Xun Li; Heng-Keang Lim; Mark T Powell; Stefanie Rassnick; Kenneth Rhodes; Ronald Russell; Robert H Scannevin; Paul F Jackson
Design and characterization of optimized adenosine A₂A/A₁ receptor antagonists for the treatment of Parkinson's disease.
Journal of medicinal chemistry 2012;55(3):1402-17.
2010: Brian C Shook; Stefanie Rassnick; Melville C Osborne; Scott Davis; Lori Westover; Jamie Boulet; Daniel Hall; Kenneth C Rupert; Geoffrey R Heintzelman; Kristin Hansen; Devraj Chakravarty; James L Bullington; Ronald Russell; Shawn Branum; Kenneth M Wells; Sandra Damon; Scott Youells; Xun Li; Derek A Beauchamp; David Palmer; Mayra Reyes; Keith T Demarest; Yuting Tang; Kenneth Rhodes; Paul F Jackson
In vivo characterization of a dual adenosine A2A/A1 receptor antagonist in animal models of Parkinson's disease.
Journal of medicinal chemistry 2010;53(22):8104-15.
2010: Brian C Shook; Stefanie Rassnick; Daniel Hall; Kenneth C Rupert; Geoffrey R Heintzelman; Kristen Hansen; Devraj Chakravarty; James L Bullington; Robert H Scannevin; Brian Magliaro; Lori Westover; Karen Carroll; Lisa Lampron; Ronald Russell; Shawn Branum; Kenneth Wells; Sandra Damon; Scott Youells; Xun Li; Mel Osbourne; Keith T Demarest; Yuting Tang; Kenneth Rhodes; Paul F Jackson
Methylene amine substituted arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.
Bioorganic & medicinal chemistry letters 2010;20(9):2864-7.
2010: Brian C Shook; Stefanie Rassnick; Devraj Chakravarty; Nathaniel Wallace; Mark Ault; Jeffrey J Crooke; J Kent Barbay; Aihua Wang; Kristi Leonard; Mark T Powell; Vernon C Alford; Daniel Hall; Kenneth C Rupert; Geoffrey R Heintzelman; Kristen Hansen; James L Bullington; Robert H Scannevin; Karen Carroll; Lisa Lampron; Lori Westover; Ronald Russell; Shawn Branum; Kenneth Wells; Sandra Damon; Scott Youells; Derek Beauchamp; Xun Li; Kenneth Rhodes; Paul F Jackson
Optimization of arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.
Bioorganic & medicinal chemistry letters 2010;20(9):2868-71.
2004: Han-Cheng Zhang; Hong Ye; Bruce R Conway; Claudia K Derian; Michael F Addo; Gee-Hong Kuo; Leonard R Hecker; Diane R Croll; Jian Li; Lori Westover; Jun Z Xu; Richard Look; Keith T Demarest; Patricia Andrade-Gordon; Bruce Damiano; Bruce E Maryanoff
3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3.
Bioorganic & medicinal chemistry letters 2004;14(12):3245-50.
2004: David J O'Neill; Lan Shen; Catherine Prouty; Bruce R Conway; Lori Westover; Jun Z Xu; Han-Cheng Zhang; Bruce E Maryanoff; William V Murray; Keith T Demarest; Gee-Hong Kuo
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors.
Bioorganic & medicinal chemistry 2004;12(12):3167-85.
2004: Jay M Matthews; Fina Liotta; William Hageman; Ralph A Rivero; Lori Westover; Maria Yang; Jun Xu; Keith T Demarest
Discovery of a dihydropyrimidine series of molecules that selectively mimic the biological actions of calcitonin.
Bioorganic & medicinal chemistry letters 2004;14(5):1155-9.
2004: Lan Shen; Catherine Prouty; Bruce R Conway; Lori Westover; Jun Z Xu; Richard Look; Xin Chen; Mary Pat Beavers; Jerry Roberts; William V Murray; Keith T Demarest; Gee-Hong Kuo
Synthesis and biological evaluation of novel macrocyclic bis-7-azaindolylmaleimides as potent and highly selective glycogen synthase kinase-3 beta (GSK-3 beta) inhibitors.
Bioorganic & medicinal chemistry 2004;12(5):1239-55.
2003: Han-Cheng Zhang; Kimberly B White; Hong Ye; David F McComsey; Claudia K Derian; Michael F Addo; Patricia Andrade-Gordon; Annette J Eckardt; Bruce R Conway; Lori Westover; Jun Z Xu; Richard Look; Keith T Demarest; Stuart Emanuel; Bruce E Maryanoff
Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3.
Bioorganic & medicinal chemistry letters 2003;13(18):3049-53.
2003: Gee-Hong Kuo; Catherine Prouty; Alan DeAngelis; Lan Shen; David J O'Neill; Chandra Shah; Peter J Connolly; William V Murray; Bruce R Conway; Peter Cheung; Lori Westover; Jun Z Xu; Richard Look; Keith T Demarest; Stuart Emanuel; Steven A Middleton; Linda Jolliffe; Mary Pat Beavers; Xin Chen
Synthesis and discovery of macrocyclic polyoxygenated bis-7-azaindolylmaleimides as a novel series of potent and highly selective glycogen synthase kinase-3beta inhibitors.
Journal of medicinal chemistry 2003;46(19):4021-31.
2003: Lisa K Minor; Lori Westover; Yan Kong; Darpana Patel; Mary Jo Wildey; Bruce R Conway; Keith T Demarest
Validation of a cell-based screen for insulin receptor modulators by quantification of insulin receptor phosphorylation.
Journal of biomolecular screening 2003;8(4):439-46.