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Michael Whalen

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Rebekah C Mannix; Jianhua Qui; Jacqueline Berglass; Jimmy Zhang; Michael J Whalen
Beneficial effect of amyloid beta after controlled cortical impact.
Heda R Dapul; Tory Gray; Christopher Lee; Eng H Lo; Josephine Lok; Juyeon Park; Jianhua Qiu; Allison Scalzo; Cenk Ayata; Ali DanEshmand; Jimmy Zhang; Michael J Whalen
Concussive injury before or after controlled cortical impact exacerbates histopathology and functional outcome in a mixed traumatic brain injury model in mice.
Phoebe H Yager; Michael J Whalen; Brian M Cummings; Natan Noviski
Nighttime telecommunication between remote staff intensivists and bedside personnel in a pediatric intensive care unit: a retrospective study.

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All Publications

2013: Rebekah C Mannix; Jianhua Qui; Jacqueline Berglass; Jimmy Zhang; Michael J Whalen
Beneficial effect of amyloid beta after controlled cortical impact.
Brain injury : [BI] 2013;27(6):743-8.
2013: Heda R Dapul; Tory Gray; Christopher Lee; Eng H Lo; Josephine Lok; Juyeon Park; Jianhua Qiu; Allison Scalzo; Cenk Ayata; Ali DanEshmand; Jimmy Zhang; Michael J Whalen
Concussive injury before or after controlled cortical impact exacerbates histopathology and functional outcome in a mixed traumatic brain injury model in mice.
Journal of neurotrauma 2013;30(5):382-91.
2012: Phoebe H Yager; Michael J Whalen; Brian M Cummings; Natan Noviski
Nighttime telecommunication between remote staff intensivists and bedside personnel in a pediatric intensive care unit: a retrospective study.
Critical care medicine 2012;40(9):2700-3.
2012: Kendall R Walker; Michael J Whalen; Eugene L Kang; Yong Shen; Giuseppina Tesco
Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(30):10423-37.
2012: Christian Foerch; Eng H Lo; Hui Wang; Zerong You; Michael J Whalen
Traumatic brain injury during warfarin anticoagulation: an experimental study in mice.
Journal of neurotrauma 2012;29(6):1150-5.
2012: Qiuhe Wu; Tao Xu; Weijun Xuan; Takahiro Ando; Tianghong Dai; Saphala Dhital; Liyi Huang; Ying-Ying Huang; Sulbha K Sharma; Michael J Whalen; Michael R Hamblin
Low-level laser therapy for closed-head traumatic brain injury in mice: effect of different wavelengths.
Lasers in surgery and medicine 2012;44(3):218-26.
2012: Lamin HAN Mbye; Luyang Tao; Jimmy Zhang; Joonyong Chung; Eyup Keles; Rajani Koppula; Mykol Larvie; Eng H Lo; Michael J Whalen
Kollidon VA64, a membrane-resealing agent, reduces histopathology and improves functional outcome after controlled cortical impact in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(3):515-24.
2012: Xiaoxia Zhu; Maria Ericsson; Kent Garber; Eng H Lo; Juyeon Park; Jianhua Qiu; Luyang Tao; Emiri Tejima-Mandeville; Michael J Whalen
Plasmalemma permeability and necrotic cell death phenotypes after intracerebral hemorrhage in mice.
Stroke; a journal of cerebral circulation 2012;43(2):524-31.
2012: Juyeon Park; Jianhua Qiu; Alexei Degterev; Eng H Lo; Jimmy Zhang; Xiaoxia Zhu; Michael J Whalen
Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(2):330-40.
2012: Jugta Khuman; Juyeon Park; James D Carroll; Chad Donahue; Jimmy Zhang; Michael J Whalen
Low-level laser light therapy improves cognitive deficits and inhibits microglial activation after controlled cortical impact in mice.
Journal of neurotrauma 2012;29(2):408-17.
2012: Song Zhao; Kazuhide Hayakawa; Eng H Lo; Josephine M Lok; Michael J Whalen; Changhong Xing; Zhanyang Yu; Gang Zhao; Xiaoying Wang
Neuroglobin-overexpression reduces traumatic brain lesion size in mice.
BMC neuroscience 2012;13():67.
2012: Rebekah C Mannix; Michael J Whalen
Traumatic brain injury, microglia, and Beta amyloid.
International journal of Alzheimer's disease 2012;2012():608732.
2011: Jugta Khuman; William P Meehan; Xiaoxia Zhu; Jianhua Qiu; Ulrike Hoffmann; Jimmy Zhang; Eric Giovannone; Eng H Lo; Michael J Whalen
Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(2):778-89.
2011: Takahiro Ando; Tianhong Dai; Ying-Ying Huang; Gitika B Kharkwal; Minoru Obara; Shunichi Sato; Sulbha K Sharma; Michael J Whalen; Qiuhe Wu; Tao Xu; Weijun Xuan; Michael R Hamblin
Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice.
PloS one 2011;6(10):e26212.
2011: Rebekah C Mannix; Jimmy Zhang; Juyeon Park; Xuan Zhang; Kiran Bilal; Kendall Walker; Rudolph E Tanzi; Giuseppina Tesco; Michael J Whalen
Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(1):351-61.
2010: Jinsheng Yang; Zerong You; Hyung-Hwan Kim; Seo-Kyoung Hwang; Jugta Khuman; Shuzhen Guo; Eng H Lo; Michael J Whalen
Genetic analysis of the role of tumor necrosis factor receptors in functional outcome after traumatic brain injury in mice.
Journal of neurotrauma 2010;27(6):1037-46.
2009: Christina H Liu; Zerong You; Charng-Ming Liu; Young R Kim; Michael J Whalen; Bruce R Rosen; Philip K Liu
Diffusion-weighted magnetic resonance imaging reversal by gene knockdown of matrix metalloproteinase-9 activities in live animal brains.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(11):3508-17.
2008: Zerong You; Sean I Savitz; Jinsheng Yang; Alexei Degterev; Junying Yuan; Gregory D Cuny; Michael A Moskowitz; Michael J Whalen
Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(9):1564-73.
2008: Phoebe H Yager; Zerong You; Tao Qin; Hyung-Hwan Kim; Kazue Takahashi; Alan B Ezekowitz; Gregory L Stahl; Michael C Carroll; Michael J Whalen
Mannose binding lectin gene deficiency increases susceptibility to traumatic brain injury in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(5):1030-9.
2008: Michael J Whalen; Turgay Dalkara; Zerong You; Jianhua Qiu; Daniela Bermpohl; Niyati Mehta; Bernhard Suter; Pradeep G Bhide; Eng H Lo; Maria Ericsson; Michael A Moskowitz
Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(3):490-505.
2007: Josephine Lok; Hui Wang; Yoshihiro Murata; Hai Hao Zhu; Tao Qin; Michael J Whalen; Eng H Lo
Effect of neuregulin-1 on histopathological and functional outcome after controlled cortical impact in mice.
Journal of neurotrauma 2007;24(12):1817-22.
2007: Josephine Lok; Punkaj Gupta; Shuzhen Guo; Woo Jean Kim; Michael J Whalen; Klaus Van Leyen; Eng H Lo
Cell-cell signaling in the neurovascular unit.
Neurochemical research 2007;32(12):2032-45.
2007: Zerong You; Jinsheng Yang; Kazue Takahashi; Phoebe H Yager; Hyung-Hwan Kim; Tao Qin; Gregory L Stahl; R Alan B Ezekowitz; Michael C Carroll; Michael J Whalen
Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(12):1954-64.
2007: Daniela Bermpohl; Zerong You; Eng H Lo; Hyung-Hwan Kim; Michael J Whalen
TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(11):1806-18.
2006: Daniela Bermpohl; Zerong You; Stanley J Korsmeyer; Michael A Moskowitz; Michael J Whalen
Traumatic brain injury in mice deficient in Bid: effects on histopathology and functional outcome.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(5):625-33.
2005: Atticus H Hainsworth; Daniela Bermpohl; Tania E Webb; Ribal S Darwish; Gary Fiskum; Jianhua Qiu; Deirdre McCarthy; Michael A Moskowitz; Michael J Whalen
Expression of cellular FLICE inhibitory proteins (cFLIP) in normal and traumatic murine and human cerebral cortex.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(8):1030-40.
2004: Negar Sheibani; Eric F Grabowski; David Schoenfeld; Michael J Whalen
Effect of granulocyte colony-stimulating factor on functional and histopathologic outcome after traumatic brain injury in mice.
Critical care medicine 2004;32(11):2274-8.
2003: Shinichi Yoshimura; Tetsuyuki Teramoto; Michael J Whalen; Michael C Irizarry; Yasushi Takagi; Jianhua Qiu; Jun Harada; Christian Waeber; Xandra O Breakefield; Michael A Moskowitz
FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice.
The Journal of clinical investigation 2003;112(8):1202-10.
2003: Parthak Prodhan; Natan Noviski; William E Butler; Emad Eskandar; P Ellen Grant; Michael J Whalen
Orbital compartment syndrome mimicking cerebral herniation in a 12-yr-old boy with severe traumatic asphyxia.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(3):367-9.
2003: Michael J Whalen
Predicting outcome in childhood bacterial meningitis: are pneumococci stronger than glutamate?
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2003;4(2):260-1.
2002: Michael J Whalen
Predicting significant vasospasm in patients with subarachnoid hemorrhage: a role for bedside microdialysis?
Critical care medicine 2002;30(5):1171-3.
2002: Jianhua Qiu; Michael J Whalen; Pedro Lowenstein; Gary Fiskum; Brenda G Fahy; Ribal S Darwish; Bizhan Aarabi; Junying Yuan; Michael A Moskowitz
Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(9):3504-11.
2002: Brian Bates; Lorenz Hirt; Sunu S Thomas; Schahram Akbarian; Dean Le; Sepideh Amin-Hanjani; Michael J Whalen; Rudolf Jaenisch; Michael A Moskowitz
Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals.
Neurobiology of disease 2002;9(1):24-37.
2000: Michael J Whalen; Timothy M Carlos; Stephen R Wisniewski; Robert S B Clark; J A Mellick; Donald W Marion; Patrick M Kochanek
Effect of neutropenia and granulocyte colony stimulating factor-induced neutrophilia on blood-brain barrier permeability and brain edema after traumatic brain injury in rats.
Critical care medicine 2000;28(11):3710-7.
2000: Robert S B Clark; Patrick M Kochanek; P David Adelson; Michael J Bell; Joseph A Carcillo; M Chen; Stephen R Wisniewski; Keri L Janesko; Michael J Whalen; Steven H Graham
Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury.
The Journal of pediatrics 2000;137(2):197-204.
2000: Michael J Whalen; Lesley A Doughty; Timothy M Carlos; Stephen R Wisniewski; Patrick M Kochanek; Joseph A Carcillo
Intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 are increased in the plasma of children with sepsis-induced multiple organ failure.
Critical care medicine 2000;28(7):2600-7.
2000: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; Stephen R Wisniewski; Michael J Bell; Robert S B Clark; Steven T DeKosky; Donald W Marion; P David Adelson
Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury.
Critical care medicine 2000;28(4):929-34.
2000: Michael J Whalen; Timothy M Carlos; C Edward Dixon; P Robichaud; Robert S B Clark; Donald W Marion; Patrick M Kochanek
Reduced brain edema after traumatic brain injury in mice deficient in P-selectin and intercellular adhesion molecule-1.
Journal of leukocyte biology 2000;67(2):160-8.
2000: Michael J Whalen; Robert S B Clark; C Edward Dixon; P Robichaud; Donald W Marion; Vincent A Vagni; S Graham; Laszlo Virag; G Hasko; R Stachlewitz; Csaba Szabó; Patrick M Kochanek
Traumatic brain injury in mice deficient in poly-ADP(ribose) polymerase: a preliminary report.
Acta neurochirurgica. Supplement 2000;76():61-4.
1999: Michael J Whalen; Robert S B Clark; C Edward Dixon; P Robichaud; Donald W Marion; Vincent A Vagni; Steven H Graham; Laszlo Virag; G Hasko; R Stachlewitz; Csaba Szabó; Patrick M Kochanek
Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(8):835-42.
1999: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; Robert S B Clark; S Heineman; Joanne K Schiding; Darcy Franicola; F Memarzadeh; W Lo; Donald W Marion; Steven T DeKosky
Neutrophils do not mediate blood-brain barrier permeability early after controlled cortical impact in rats.
Journal of neurotrauma 1999;16(7):583-94.
1999: Michael J Whalen; Timothy M Carlos; Robert S B Clark; Patrick M Kochanek
An acute inflammatory response to the use of granulocyte colony-stimulating factor to prevent infections in patients with brain injury: what about the brain?
Critical care medicine 1999;27(5):1014-8.
1999: F A Maffei; R P Heine; Michael J Whalen; LF Mortimer; J A Carcillo
Levels of antimicrobial molecules defensin and lactoferrin are elevated in the cerebrospinal fluid of children with meningitis.
Pediatrics 1999;103(5 Pt 1):987-92.
1999: Michael J Whalen; Timothy M Carlos; C Edward Dixon; Joanne K Schiding; Robert S B Clark; E Baum; Hong Qu Yan; Donald W Marion; Patrick M Kochanek
Effect of traumatic brain injury in mice deficient in intercellular adhesion molecule-1: assessment of histopathologic and functional outcome.
Journal of neurotrauma 1999;16(4):299-309.
1998: P M Kochanek; S Venkataraman; Michael J Whalen; H Dalton
Is the administration of inhaled nitric oxide (NO) associated with electroencephalogram abnormalities? There is NO harm in looking.
Critical care medicine 1998;26(11):1788-9.
1998: Joseph A Carcillo; Kenneth R Korzekwa; G S Jones; Robert A Parise; Delbert G Gillespie; Michael J Whalen; P M Kochanek; Robert A Branch; Curtis K Kost
The cytochrome P450 suicide inhibitor, 1-aminobenzotriazole, sensitizes rats to zymosan-induced toxicity.
Research communications in molecular pathology and pharmacology 1998;102(1):57-68.
1998: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; Stephen R Wisniewski; Michael J Bell; Joseph A Carcillo; Robert S B Clark; Steven T DeKosky; P David Adelson
Soluble adhesion molecules in CSF are increased in children with severe head injury.
Journal of neurotrauma 1998;15(10):777-87.
1998: Michael J Whalen; Timothy M Carlos; Patrick M Kochanek; S Heineman
Blood-brain barrier permeability, neutrophil accumulation and vascular adhesion molecule expression after controlled cortical impact in rats: a preliminary study.
Acta neurochirurgica. Supplement 1998;71():212-4.
1998: P David Adelson; Michael J Whalen; Patrick M Kochanek; P Robichaud; Timothy M Carlos
Blood brain barrier permeability and acute inflammation in two models of traumatic brain injury in the immature rat: a preliminary report.
Acta neurochirurgica. Supplement 1998;71():104-6.
1997: Michael J Whalen; Timothy M Carlos; Robert S B Clark; Donald W Marion; Steven T DeKosky; S Heineman; Joanne K Schiding; F Memarzadeh; Patrick M Kochanek
The effect of brain temperature on acute inflammation after traumatic brain injury in rats.
Journal of neurotrauma 1997;14(8):561-72.
1997: Michael J Bell; Patrick M Kochanek; Lesley A Doughty; Joseph A Carcillo; P David Adelson; Robert S B Clark; Stephen R Wisniewski; Michael J Whalen; Steven T DeKosky
Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children.
Journal of neurotrauma 1997;14(7):451-7.
1997: Michael J Whalen; Timothy M Carlos; Robert S B Clark; Donald W Marion; M S DeKosky; S Heineman; Joanne K Schiding; F Memarzadeh; C Edward Dixon; Patrick M Kochanek
The relationship between brain temperature and neutrophil accumulation after traumatic brain injury in rats.
Acta neurochirurgica. Supplement 1997;70():260-1.
1997: Michael J Bell; Patrick M Kochanek; Lesley A Doughty; Joseph A Carcillo; P David Adelson; Robert S B Clark; Michael J Whalen; Steven T DeKosky
Comparison of the interleukin-6 and interleukin-10 response in children after severe traumatic brain injury or septic shock.
Acta neurochirurgica. Supplement 1997;70():96-7.