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Craig Wheelock

Research Profile

Chemicals & Drugs

Living Beings

Genes & Molecular Sequences

Molecular Structure

Anatomy

Microsomes, Liver

Concepts & Ideas

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Publications

TOP 3
Susanna L Lundström; Gunnar Nilsson; Rohit Saluja; Mikael Adner; Jesper Z Haeggström; Craig E Wheelock
Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations.
Stuart Snowden; Sven-Erik Dahlén; Craig E Wheelock
Application of metabolomics approaches to the study of respiratory diseases.
Gemma M Kirwan; Robert Kleemann; Johan Trygg; Elwin R Verheij; Susumu Goto; Erik Johansson; Asa M Wheelock; Craig E Wheelock
Building multivariate systems biology models.

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All Publications

2013: Susanna L Lundström; Gunnar Nilsson; Rohit Saluja; Mikael Adner; Jesper Z Haeggström; Craig E Wheelock
Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations.
Journal of lipid research 2013;54(1):116-26.
2012: Stuart Snowden; Sven-Erik Dahlén; Craig E Wheelock
Application of metabolomics approaches to the study of respiratory diseases.
Bioanalysis 2012;4(18):2265-90.
2012: Gemma M Kirwan; Robert Kleemann; Johan Trygg; Elwin R Verheij; Susumu Goto; Erik Johansson; Asa M Wheelock; Craig E Wheelock
Building multivariate systems biology models.
Analytical chemistry 2012;84(16):7064-71.
2012: Diego Diez; David J Erle; John V Fahy; Susumu Goto; Asa M Wheelock; Prescott G Woodruff; Craig E Wheelock
Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics.
BMC medical genomics 2012;5():27.
2012: Susanna L Lundström; Sarah Thunberg; Marianne van Hage; Anders Eklund; Guro Gafvelin; Reidar Grönneberg; Johan Grunewald; Jesper Z Haeggström; Bruce D Hammock; Henrik J Källberg; Jun Yang; Asa M Wheelock; Craig E Wheelock
Allergic asthmatics show divergent lipid mediator profiles from healthy controls both at baseline and following birch pollen provocation.
PloS one 2012;7(3):e33780.
2011: Susanna L Lundström; Malin Nording; Magnus Sköld; Magnus Svartengren; Anders Eklund; Johan Grunewald; Jesper Z Haeggström; Bruce D Hammock; Anna Klepczynska-Nyström; Britt-Marie Larsson; Bettina Levänen; Asa M Wheelock; Craig E Wheelock
Asthmatics exhibit altered oxylipin profiles compared to healthy individuals after subway air exposure.
PloS one 2011;6(8):e23864.
2010: Sayaka Mizutani; Michihiro Tanaka; Craig E Wheelock; Minoru Kanehisa; Susumu Goto
PHYLOGENETIC ANALYSIS OF LIPID MEDIATOR GPCRs.
Genome informatics. International Conference on Genome Informatics 2010;24(1):116-26.
2010: Diego Diez; Nelson Hayes; Nicolas Joannin; Johan Normark; Minoru Kanehisa; Mats Wahlgren; Craig E Wheelock; Susumu Goto
varDB: a database of antigenic variant sequences--current status and future prospects.
Acta tropica 2010;114(3):144-51.
2010: Diego Diez; Asa M Wheelock; Susumu Goto; Jesper Z Haeggström; Gabrielle Paulsson-Berne; Göran K Hansson; Ulf Hedin; Anders Gabrielsen; Craig E Wheelock
The use of network analyses for elucidating mechanisms in cardiovascular disease.
Molecular bioSystems 2010;6(2):289-304.
2009: C Nelson Hayes; Diego Diez; Nicolas Joannin; Minoru Kanehisa; Mats Wahlgren; Craig E Wheelock; Susumu Goto
Tools for investigating mechanisms of antigenic variation: new extensions to varDB.
Genome informatics. International Conference on Genome Informatics 2009;23(1):46-59.
2008: Nelson Hayes; Diego Diez; Nicolas Joannin; Wataru Honda; Minoru Kanehisa; Mats Wahlgren; Craig E Wheelock; Susumu Goto
varDB: a pathogen-specific sequence database of protein families involved in antigenic variation.
Bioinformatics (Oxford, England) 2008;24(21):2564-5.
2008: Craig E Wheelock; Michael E Colvin; James R Sanborn; Bruce D Hammock
Substituted 3-phenylpropenoates and related analogs: electron ionization mass spectral fragmentation and density functional theory calculations.
Journal of mass spectrometry : JMS 2008;43(8):1053-62.
2008: Christophe Morisseau; John William Newman; Craig E Wheelock; Thomas Hill Iii; Dexter Morin; Alan R Buckpitt; Bruce D Hammock
Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase.
Chemical research in toxicology 2008;21(4):951-7.
2008: Craig E Wheelock; Jenny Forshed; Susumu Goto; Bruce D Hammock; John William Newman
Effects of pyridine exposure upon structural lipid metabolism in Swiss Webster mice.
Chemical research in toxicology 2008;21(3):583-90.
2008: Craig E Wheelock; Kosuke Nishi; Andy Ying; Paul D Jones; Michael E Colvin; Marilyn M Olmstead; Bruce D Hammock
Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH).
Bioorganic & medicinal chemistry 2008;16(4):2114-30.
2007: Tadashi Kadowaki; Craig E Wheelock; Tetsuya Adachi; Taku Kudo; Shinobu Okamoto; Nobuya Tanaka; Koichiro Tonomura; Gozoh Tsujimoto; Hiroshi Mamitsuka; Susumu Goto; Minoru Kanehisa
Identification of endocrine disruptor biodegradation by integration of structure-activity relationship with pathway analysis.
Environmental science & technology 2007;41(23):7997-8003.
2007: Randy M Wadkins; Janice L Hyatt; Carol C Edwards; Lyudmila Tsurkan; Matthew R Redinbo; Craig E Wheelock; Paul D Jones; Bruce D Hammock; Philip Potter
Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds.
Molecular pharmacology 2007;71(3):713-23.
2006: Mark Wogulis; Craig E Wheelock; Shizuo G Kamita; Andrew C Hinton; Paul A Whetstone; Bruce D Hammock; David K Wilson
Structural studies of a potent insect maturation inhibitor bound to the juvenile hormone esterase of Manduca sexta.
Biochemistry 2006;45(13):4045-57.
2006: Craig E Wheelock; Jeff L Miller; Mike J Miller; Bryn M Phillips; Sarah A Huntley; Shirley J Gee; Ronald S Tjeerdema; Bruce D Hammock
Use of carboxylesterase activity to remove pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca in toxicity identification evaluations.
Environmental toxicology and chemistry / SETAC 2006;25(4):973-84.
2006: Craig E Wheelock; Yoshiaki Nakagawa; Toshiyuki Harada; Nobuhiro Oikawa; Miki Akamatsu; Guy Smagghe; Dimitra Stefanou; Kostas Iatrou; Luc Swevers
High-throughput screening of ecdysone agonists using a reporter gene assay followed by 3-D QSAR analysis of the molting hormonal activity.
Bioorganic & medicinal chemistry 2006;14(4):1143-59.
2005: Kyung-Don Kang; Paul D Jones; Huazhang Huang; Rong Zhang; Lyudmila A Mostovich; Craig E Wheelock; Takaho Watanabe; Lyudmila F Gulyaeva; Bruce D Hammock
Evaluation of alpha-cyano ethers as fluorescent substrates for assay of cytochrome P450 enzyme activity.
Analytical biochemistry 2005;344(2):183-92.
2005: Craig E Wheelock; Kai J Eder; Ingeborg Werner; Huazhang Huang; Paul D Jones; Benjamin F Brammell; Adria A Elskus; Bruce D Hammock
Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos.
Aquatic toxicology (Amsterdam, Netherlands) 2005;74(2):172-92.
2005: Craig E Wheelock; Jeff L Miller; Mike J Miller; Bryn M Phillips; Shirley J Gee; Ronald S Tjeerdema; Bruce D Hammock
Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca.
Aquatic toxicology (Amsterdam, Netherlands) 2005;74(1):47-52.
2004: Craig E Wheelock; Jeff L Miller; Mike J Miller; Shirley J Gee; Guomin Shan; Bruce D Hammock
Development of toxicity identification evaluation procedures for pyrethroid detection using esterase activity.
Environmental toxicology and chemistry / SETAC 2004;23(11):2699-708.
2004: Jeanette E Stok; Andrey Goloshchapov; Cheng Song; Craig E Wheelock; Maher B H Derbel; Christophe Morisseau; Bruce D Hammock
Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis.
Archives of biochemistry and biophysics 2004;430(2):247-55.
2004: Jeanette E Stok; Huazhang Huang; Paul D Jones; Craig E Wheelock; Christophe Morisseau; Bruce D Hammock
Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes.
The Journal of biological chemistry 2004;279(28):29863-9.
2004: Rory D McAbee; Kyung-Don Kang; Matthew A Stanich; Julie A Christiansen; Craig E Wheelock; Allan D Inman; Bruce D Hammock; Anthony J Cornel
Pyrethroid tolerance in Culex pipiens pipiens var molestus from Marin County, California.
Pest management science 2004;60(4):359-68.
2003: Shizuo G Kamita; Andrew C Hinton; Craig E Wheelock; Mark Wogulis; David K Wilson; Nicola M Wolf; Jeanette E Stok; Bertold Hock; Bruce D Hammock
Juvenile hormone (JH) esterase: why are you so JH specific?
Insect biochemistry and molecular biology 2003;33(12):1261-73.
2003: Craig E Wheelock; Yoshiaki Nakagawa; Miki Akamatsu; Bruce D Hammock
Use of classical and 3-D QSAR to examine the hydration state of juvenile hormone esterase inhibitors.
Bioorganic & medicinal chemistry 2003;11(23):5101-16.
2003: Craig E Wheelock; Asa M Wheelock; Rong Zhang; Jeanette E Stok; Christophe Morisseau; Susanna E Le Valley; Carol E Green; Bruce D Hammock
Evaluation of alpha-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes.
Analytical biochemistry 2003;315(2):208-22.
2003: Debra L Denton; Craig E Wheelock; Shauna A Murray; Linda A Deanovic; Bruce D Hammock; David E Hinton
Joint acute toxicity of esfenvalerate and diazinon to larval fathead minnows (Pimephales promelas).
Environmental toxicology and chemistry / SETAC 2003;22(2):336-41.
2002: Craig E Wheelock; Michael E Colvin; Ippei Uemura; Marilyn M Olmstead; James R Sanborn; Yoshiaki Nakagawa; A Daniel Jones; Bruce D Hammock
Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors.
Journal of medicinal chemistry 2002;45(25):5576-93.
2002: Craig E Wheelock; T A Baumgartner; John William Newman; MF Wolfe; Ronald S Tjeerdema
Effect of nutritional state on Hsp60 levels in the rotifer Brachionus plicatilis following toxicant exposure.
Aquatic toxicology (Amsterdam, Netherlands) 2002;61(1-2):89-93.
2002: Christophe Morisseau; Marvin H Goodrow; John William Newman; Craig E Wheelock; Deanna L Dowdy; Bruce D Hammock
Structural refinement of inhibitors of urea-based soluble epoxide hydrolases.
Biochemical pharmacology 2002;63(9):1599-608.
2001: Craig E Wheelock; Tonya F Severson; Bruce D Hammock
Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility.
Chemical research in toxicology 2001;14(12):1563-72.
2001: John William Newman; Debra L Denton; Christophe Morisseau; CS Koger; Craig E Wheelock; David E Hinton; Bruce D Hammock
Evaluation of fish models of soluble epoxide hydrolase inhibition.
Environmental health perspectives 2001;109(1):61-6.
2000: Yoshiaki Nakagawa; Craig E Wheelock; Christophe Morisseau; Marvin H Goodrow; B G Hammock; Bruce D Hammock
3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues.
Bioorganic & medicinal chemistry 2000;8(11):2663-73.
1999: Craig E Wheelock; MF Wolfe; H Olsen; Ronald S Tjeerdema; ML Sowby
Hsp60-induced tolerance in the rotifer Brachionus plicatilis exposed to multiple environmental contaminants.
Archives of environmental contamination and toxicology 1999;36(3):281-7.