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Adam Whelan

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Michael Coad; Martin Vordermeier; Derek J Clifford; Adam O Whelan
The consequences of vaccination with the Johne's disease vaccine, Gudair, on diagnosis of bovine tuberculosis.
B L Khatri; Derek J Clifford; Michael Coad; R Glyn Hewinson; Adam O Whelan; Martin Vordermeier
A natural-transmission model of bovine tuberculosis provides novel disease insights.
Martin Vordermeier; Adam O Whelan
ELISPOT assays to enumerate bovine IFN-γ-secreting cells for the development of novel vaccines against bovine tuberculosis.

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All Publications

2013: Michael Coad; Martin Vordermeier; Derek J Clifford; Adam O Whelan
The consequences of vaccination with the Johne's disease vaccine, Gudair, on diagnosis of bovine tuberculosis.
The Veterinary record 2013;172(10):266.
2012: B L Khatri; Derek J Clifford; Michael Coad; R Glyn Hewinson; Adam O Whelan; Martin Vordermeier
A natural-transmission model of bovine tuberculosis provides novel disease insights.
The Veterinary record 2012;171(18):448.
2012: Martin Vordermeier; Adam O Whelan
ELISPOT assays to enumerate bovine IFN-γ-secreting cells for the development of novel vaccines against bovine tuberculosis.
Methods in molecular biology (Clifton, N.J.) 2012;792():219-27.
2011: Adam O Whelan; Derek J Clifford; Michael Coad; R Glyn Hewinson; B L Upadhyay; Martin Vordermeier
Lack of correlation between BCG-induced tuberculin skin test sensitisation and protective immunity in cattle.
Vaccine 2011;29(33):5453-8.
2010: Adam O Whelan; Derek Clifford; Bhagwati Upadhyay; Eleanor L Breadon; James McNair; Glyn R Hewinson; Martin Vordermeier
Development of a skin test for bovine tuberculosis for differentiating infected from vaccinated animals.
Journal of clinical microbiology 2010;48(9):3176-81.
2010: Michael Coad; Derek Clifford; Shelley G Rhodes; R Glyn Hewinson; Martin Vordermeier; Adam O Whelan
Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased interleukin-1 beta responses.
Veterinary research 2010;41(2):14.
2010: Adam O Whelan; Michael Coad; Paul J Cockle; Glyn Hewinson; Martin Vordermeier; Stephen Gordon
Revisiting host preference in the Mycobacterium tuberculosis complex: experimental infection shows M. tuberculosis H37Rv to be avirulent in cattle.
PloS one 2010;5(1):e8527.
2008: G S Dean; Shelley G Rhodes; Michael Coad; Adam O Whelan; Paul R Wheeler; B Villareal-Ramos; E Mead; L Johnson; Derek J Clifford; R Glyn Hewinson; Martin Vordermeier
Isoniazid treatment of Mycobacterium bovis in cattle as a model for human tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2008;88(6):586-94.
2008: Adam O Whelan; D Craig Wright; Mark A Chambers; Mahavir Singh; R Glyn Hewinson; Martin Vordermeier
Evidence for enhanced central memory priming by live Mycobacterium bovis BCG vaccine in comparison with killed BCG formulations.
Vaccine 2008;26(2):166-73.
2007: Shelley G Rhodes; Jason sawyer; Adam O Whelan; Gillian S Dean; Michael Coad; Katie Ewer; Andreas Waldvogel; Anthony Zakher; Derek J Clifford; R Glyn Hewinson; Martin Vordermeier
Is interleukin-4delta3 splice variant expression in bovine tuberculosis a marker of protective immunity?
Infection and immunity 2007;75(6):3006-13.
2007: Michael Coad; R Glyn Hewinson; Derek J Clifford; Martin Vordermeier; Adam O Whelan
Influence of skin testing and blood storage on interferon-gamma production in cattle affected naturally with Mycobacterium bovis.
The Veterinary record 2007;160(19):660-2.
2005: Gillian S Dean; Shelley G Rhodes; Michael Coad; Adam O Whelan; Paul J Cockle; Derek J Clifford; R Glyn Hewinson; Martin Vordermeier
Minimum infective dose of Mycobacterium bovis in cattle.
Infection and immunity 2005;73(10):6467-71.
2004: Adam O Whelan; Michael Coad; Z A A Peck; Derek J Clifford; R Glyn Hewinson; Martin Vordermeier
Influence of skin testing and overnight sample storage on blood-based diagnosis of bovine tuberculosis.
The Veterinary record 2004;155(7):204-6.
2003: Adam O Whelan; Jayne C Hope; C J Howard; Derek J Clifford; R Glyn Hewinson; Martin Vordermeier
Modulation of the bovine delayed-type hypersensitivity responses to defined mycobacterial antigens by a synthetic bacterial lipopeptide.
Infection and immunity 2003;71(11):6420-5.
2003: Jayne C Hope; Adam O Whelan; R Glyn Hewinson; Martin Vordermeier; Chris J Howard
Maturation of bovine dendritic cells by lipopeptides.
Veterinary immunology and immunopathology 2003;95(1-2):21-31.
2003: Stephen L Michell; Adam O Whelan; Paul R Wheeler; Maria Panico; Richard L Easton; A Tony Etienne; Stuart M Haslam; Anne Dell; Howard R Morris; Andrew J Reason; Jean Louis Herrmann; Douglas B Young; R Glyn Hewinson
The MPB83 antigen from Mycobacterium bovis contains O-linked mannose and (1-->3)-mannobiose moieties.
The Journal of biological chemistry 2003;278(18):16423-32.
2003: Martin Vordermeier; Adam O Whelan; R Glyn Hewinson
Recognition of mycobacterial epitopes by T cells across mammalian species and use of a program that predicts human HLA-DR binding peptides to predict bovine epitopes.
Infection and immunity 2003;71(4):1980-7.
2002: Martin Vordermeier; Mark A Chambers; Paul J Cockle; Adam O Whelan; Jennifer Simmons; R Glyn Hewinson
Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis.
Infection and immunity 2002;70(6):3026-32.
2002: Mark A Chambers; Keith Jahans; Adam O Whelan; Catherine Hughes; Robin Sayers; Alan Perkins; R Glyn Hewinson
Simple objective measurement of the cutaneous delayed-type hypersensitivity reaction to tuberculin using spectrophotometry.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2002;8(2):89-93.
2001: Mark A Chambers; Ann Williams; Dolores Gavier-Widén; Adam O Whelan; C Hughes; Graham Hall; M S Lever; Philip D Marsh; R Glyn Hewinson
A guinea pig model of low-dose Mycobacterium bovis aerogenic infection.
Veterinary microbiology 2001;80(3):213-26.
2001: Martin Vordermeier; Adam O Whelan; Paul J Cockle; L Farrant; N Palmer; R Glyn Hewinson
Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle.
Clinical and diagnostic laboratory immunology 2001;8(3):571-8.
2000: Martin Vordermeier; Paul J Cockle; Adam O Whelan; S Rhodes; Mark A Chambers; Derek J Clifford; K Huygen; Ricardo E Tascon; Douglas B Lowrie; M Joseph Colston; R Glyn Hewinson
Effective DNA vaccination of cattle with the mycobacterial antigens MPB83 and MPB70 does not compromise the specificity of the comparative intradermal tuberculin skin test.
Vaccine 2000;19(9-10):1246-55.
2000: Mark A Chambers; Ann Williams; Dolores Gavier-Widén; Adam O Whelan; Graham Hall; Philip D Marsh; B R Bloom; William R. Jacobs Jr.; R Glyn Hewinson
Identification of a Mycobacterium bovis BCG auxotrophic mutant that protects guinea pigs against M. bovis and hematogenous spread of Mycobacterium tuberculosis without sensitization to tuberculin.
Infection and immunity 2000;68(12):7094-9.
2000: Martin Vordermeier; Paul J Cockle; Adam O Whelan; S Rhodes; R Glyn Hewinson
Toward the development of diagnostic assays to discriminate between Mycobacterium bovis infection and bacille Calmette-Guérin vaccination in cattle.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30 Suppl 3():S291-8.
2000: Mark A Chambers; Martin Vordermeier; Adam O Whelan; N Commander; Ricardo E Tascon; Douglas B Lowrie; R Glyn Hewinson
Vaccination of mice and cattle with plasmid DNA encoding the Mycobacterium bovis antigen MPB83.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30 Suppl 3():S283-7.
2000: Shelley G Rhodes; D Gavier-Widen; B M Buddle; Adam O Whelan; Mahavir Singh; R Glyn Hewinson; Martin Vordermeier
Antigen specificity in experimental bovine tuberculosis.
Infection and immunity 2000;68(5):2573-8.
1999: Martin Vordermeier; P C Cockle; Adam O Whelan; S Rhodes; N Palmer; D Bakker; R Glyn Hewinson
Development of diagnostic reagents to differentiate between Mycobacterium bovis BCG vaccination and M. bovis infection in cattle.
Clinical and diagnostic laboratory immunology 1999;6(5):675-82.