FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

John Wherry

Research Profile

Anatomy

Physiology

Living Beings

Disorders

Chemicals & Drugs

Concepts & Ideas

T-Lymphocyte Subsets

Co-author Network

Publications

TOP 3
Christelle Harly; E John Wherry; Avinash Bhandoola
Deconstructing development.
Pamela M Odorizzi; E John Wherry
Immunology. An interferon paradox.
Laura M McLane; Jordan S Orange; E John Wherry; Pinaki Banerjee; Gabriela L Cosma; George Makedonas; Michael R Betts
Differential localization of T-bet and Eomes in CD8 T cell memory populations.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of John Wherry (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Christelle Harly; E John Wherry; Avinash Bhandoola
Deconstructing development.
Nature immunology 2013;14(6):529-31.
2013: Pamela M Odorizzi; E John Wherry
Immunology. An interferon paradox.
Science (New York, N.Y.) 2013;340(6129):155-6.
2013: Laura M McLane; Jordan S Orange; E John Wherry; Pinaki Banerjee; Gabriela L Cosma; George Makedonas; Michael R Betts
Differential localization of T-bet and Eomes in CD8 T cell memory populations.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(7):3207-15.
2013: Brian J Laidlaw; Laurel A Monticelli; Krystyna Mozdzanowska; Michael C Abt; Mohammed-Alkhatim A Ali; Jill M Angelosanto; David Artis; Vilma Decman; Jan Erikson; Amaya I Wolf; E John Wherry
Cooperativity between CD8+ T cells, non-neutralizing antibodies, and alveolar macrophages is important for heterosubtypic influenza virus immunity.
PLoS pathogens 2013;9(3):e1003207.
2012: Travis A Doering; Michael A Paley; Jill M Angelosanto; Alison Crawford; Carly G Ziegler; E John Wherry
Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.
Immunity 2012;37(6):1130-44.
2012: Michael A Paley; Steven L Reiner; Elizabeth J Robertson; Burton E Barnett; Elizabeth K Bikoff; Douglas V Dolfi; Jonathan B Johnnidis; Daniela C Kroy; Georg M Lauer; Pamela M Odorizzi; E John Wherry
Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.
Science (New York, N.Y.) 2012;338(6111):1220-5.
2012: Erietta Stelekati; E John Wherry
Chronic bystander infections and immunity to unrelated antigens.
Cell host & microbe 2012;12(4):458-69.
2012: Jill M Angelosanto; Shawn D Blackburn; Alison Crawford; E John Wherry
Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection.
Journal of virology 2012;86(15):8161-70.
2012: Michael C Abt; Theresa Alenghat; Marcelo Antenus; Travis A Doering; Jan Erikson; Laurel A Monticelli; Lisa C Osborne; Michael A Paley; Gregory F Sonnenberg; E John Wherry; Katie L Williams; David Artis
Commensal bacteria calibrate the activation threshold of innate antiviral immunity.
Immunity 2012;37(1):158-70.
2012: Kerry A Casey; Kathryn A Fraser; Kristin A Hogquist; Philip J Lucas; Amy Moran; Jason M Schenkel; Vaiva Vezys; E John Wherry; Michael C Abt; David Artis; Lalit K Beura; David Masopust
Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(10):4866-75.
2012: Pamela M Odorizzi; E John Wherry
Inhibitory receptors on lymphocytes: insights from infections.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(7):2957-65.
2012: Tao Wang; E John Wherry; Min Xiao; Catherine Huang; Alfonso Lopez-Coral; Kimberly A Slentz-Kesler; Russel E Kaufman
K12/SECTM1, an interferon-γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation.
Journal of leukocyte biology 2012;91(3):449-59.
2012: Vilma Decman; Travis A Doering; Hildegund C J Ertl; Daniel R Goldstein; Brian J Laidlaw; Jin Leng; E John Wherry
Defective CD8 T cell responses in aged mice are due to quantitative and qualitative changes in virus-specific precursors.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(4):1933-41.
2011: Laurel A Monticelli; Taheri Sathaliyawala; Gregory F Sonnenberg; Damian Turner; E John Wherry; Cliff Y Yang; Carly G K Ziegler; Michael C Abt; Theresa Alenghat; Jill M Angelosanto; Ronald G Collman; Joshua M Diamond; Travis A Doering; Donna L Farber; Ananda W Goldrath; Masaru Kubota; Brian J Laidlaw; David Artis
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.
Nature immunology 2011;12(11):1045-54.
2011: Mark C Siracusa; Jonathan M Spergel; E John Wherry; Steven F Ziegler; Antonella Cianferoni; Michael R Comeau; Travis A Doering; Emily C Dudek; Mark B Headley; David A Hill; Heidi K Jessup; Taku Kambayashi; Brian S Kim; Masato Kubo; Steven A Saenz; Lori A Siegel; David Artis
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation.
Nature 2011;477(7363):229-33.
2011: alison crawford; Kim Lynn Nadwodny; Jill Marie Angelosanto; Shawn D Blackburn; E John Wherry
A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection.
PLoS pathogens 2011;7(7):e1002098.
2011: Charlly Kao; Kenneth J Oestreich; Michael A Paley; Steven L Reiner; Amy S Weinmann; Mohammed-Alkhatim A Ali; Jill M Angelosanto; Jeremy M Boss; alison crawford; Andrew M Intlekofer; E John Wherry
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.
Nature immunology 2011;12(7):663-71.
2011: Valerie P Zediak; E John Wherry; Shelley L Berger
The contribution of epigenetic memory to immunologic memory.
Current opinion in genetics & development 2011;21(2):154-9.
2011: Adeeb Rahman; Ruan Zhang; Christopher D Blosser; Baidong Hou; Anthony L Defranco; Jonathan S Maltzman; E John Wherry; Laurence A Turka
Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88.
Blood 2011;117(11):3123-30.
2011: Valerie P Zediak; Jonathan B Johnnidis; E John Wherry; Shelley L Berger
Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(5):2705-9.
2010: Karla R Wiehagen; Evann Corbo; Michelle Schmidt; Haina Shin; E John Wherry; Jonathan S Maltzman
Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells.
Blood 2010;116(25):5560-70.
2010: Jennifer E Smith-Garvin; Jeremy C Burns; Mercy Gohil; Tao Zou; Jiyeon S Kim; Jonathan S Maltzman; E John Wherry; Gary A Koretzky; Martha S Jordan
T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool.
Blood 2010;116(25):5548-59.
2010: Sara Samimi; Bernice M Benoit; Katherine Evans; E John Wherry; Louise C Showe; Maria Wysocka; Alain H Rook
Increased programmed death-1 expression on CD4+ T cells in cutaneous T-cell lymphoma: implications for immune suppression.
Archives of dermatology 2010;146(12):1382-8.
2010: Arnob Banerjee; Scott M Gordon; Andrew M Intlekofer; Michael A Paley; Erin C Mooney; Tullia Lindsten; E John Wherry; Steven L Reiner
Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):4988-92.
2010: Michael Quigley; Florencia Pereyra; Björn Nilsson; Filippos Porichis; Catia Fonseca; Quentin Eichbaum; Boris Julg; Jonathan L Jesneck; Kathleen Brosnahan; Sabrina Imam; Kate Russell; Ildiko Toth; Alicja Piechocka-Trocha; Douglas Dolfi; Jill Angelosanto; alison crawford; Haina Shin; Douglas S Kwon; Jennifer Zupkosky; Loise Francisco; Gordon J Freeman; E John Wherry; Daniel E Kaufmann; Bruce D Walker; Benjamin Ebert; W Nicholas Haining
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.
Nature medicine 2010;16(10):1147-51.
2010: Michael A Paley; E John Wherry
TCF-1 flips the switch on Eomes.
Immunity 2010;33(2):145-7.
2010: Jill M Angelosanto; E John Wherry
Transcription factor regulation of CD8+ T-cell memory and exhaustion.
Immunological reviews 2010;236():167-75.
2010: Keturah E Brown; Gordon J Freeman; E John Wherry; Arlene H Sharpe
Role of PD-1 in regulating acute infections.
Current opinion in immunology 2010;22(3):397-401.
2010: David Masopust; Daniel Choo; Vaiva Vezys; E John Wherry; Jaikumar Duraiswamy; Rama Akondy; Jun Wang; Kerry A Casey; Daniel L Barber; Kim S Kawamura; Kathryn A Fraser; Richard J Webby; Volker Brinkmann; Eugene C Butcher; Kenneth A Newell; Rafi Ahmed
Dynamic T cell migration program provides resident memory within intestinal epithelium.
The Journal of experimental medicine 2010;207(3):553-64.
2010: George Makedonas; Natalie Hutnick; Danielle Haney; Alexandra C Amick; Jay Gardner; Gabriela Cosma; Adam R Hersperger; Douglas Dolfi; E John Wherry; Guido Ferrari; Michael R Betts
Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells.
PLoS pathogens 2010;6(3):e1000798.
2010: W Nicholas Haining; E John Wherry
Integrating genomic signatures for immunologic discovery.
Immunity 2010;32(2):152-61.
2009: Haina Shin; Shawn D Blackburn; Andrew M Intlekofer; Charlly Kao; Jill M Angelosanto; Steven L Reiner; E John Wherry
A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.
Immunity 2009;31(2):309-20.
2009: alison crawford; E John Wherry
Editorial: Therapeutic potential of targeting BTLA.
Journal of leukocyte biology 2009;86(1):5-8.
2009: Joseph N Blattman; E John Wherry; Sang-Jun Ha; Robbert van der Most; Rafi Ahmed
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection.
Journal of virology 2009;83(9):4386-94.
2009: alison crawford; E John Wherry
The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses.
Current opinion in immunology 2009;21(2):179-86.
2009: Emma H Wilson; Tajie Harris; Paul Mrass; Beena John; Elia D Tait; Gregory F Wu; Marion Pepper; E John Wherry; Florence Dzierzinski; David Roos; Philip G Haydon; Tom Li Stephen; Wolfgang Weninger; Christopher A Hunter
Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers.
Immunity 2009;30(2):300-11.
2009: Amaya I Wolf; Darya Buehler; Scott E Hensley; Lois L Cavanagh; E John Wherry; Philippe Kastner; Susan Chan; Wolfgang Weninger
Plasmacytoid dendritic cells are dispensable during primary influenza virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(2):871-9.
2008: Shawn D Blackburn; Haina Shin; Gordon J Freeman; E John Wherry
Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15016-21.
2008: Adeeb Rahman; Weiguo Cui; David F Larosa; D K Taylor; Jidong Zhang; Daniel R Goldstein; E John Wherry; Susan M Kaech; Laurence A Turka
MyD88 plays a critical T cell-intrinsic role in supporting CD8 T cell expansion during acute lymphocytic choriomeningitis virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):3804-10.
2008: W Nicholas Haining; Benjamin L Ebert; Aravind Subrmanian; E John Wherry; Quentin Eichbaum; John W Evans; Raymond Mak; Stephen Rivoli; Jennifer Pretz; Jill Angelosanto; John S Smutko; Bruce D Walker; Susan M Kaech; Rafi Ahmed; Lee M Nadler; Todd R Golub
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):1859-68.
2008: Andrew M Intlekofer; Arnob Banerjee; Naofumi Takemoto; Scott M Gordon; Caitlin S Dejong; Haina Shin; Christopher A Hunter; E John Wherry; Tullia Lindsten; Steven L Reiner
Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.
Science (New York, N.Y.) 2008;321(5887):408-11.
2008: Nobuhiro Nakamoto; David Edward Kaplan; Jennifer Coleclough; Yun Li; Mary E Valiga; Mary Kaminski; Abraham Shaked; Kim Olthoff; Emma Gostick; David A Price; Gordon J Freeman; E John Wherry; Kyong-Mi Chang
Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization.
Gastroenterology 2008;134(7):1927-37, 1937.e1-2.
2008: Zheng Zhang; Ji-Yuan Zhang; E John Wherry; Bo Jin; Bin Xu; Zheng-Sheng Zou; Shu-Ye Zhang; Bao-Sen Li; Hui-Feng Wang; Hao Wu; George K K Lau; Yang-Xin Fu; Fu-Sheng Wang
Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B.
Gastroenterology 2008;134(7):1938-49, 1949.e1-3.
2008: Janel Hart Chatraw; E John Wherry; Rafi Ahmed; Zoher F Kapasi
Diminished primary CD8 T cell response to viral infection during protein energy malnutrition in mice is due to changes in microenvironment and low numbers of viral-specific CD8 T cell precursors.
The Journal of nutrition 2008;138(4):806-12.
2008: Sang-Jun Ha; Scott N Mueller; E John Wherry; Daniel L Barber; Rachael D Aubert; Arlene H Sharpe; Gordon J Freeman; Rafi Ahmed
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection.
The Journal of experimental medicine 2008;205(3):543-55.
2008: Marcio O Lasaro; Nia Tatsis; Scott E Hensley; J Charles Whitbeck; Shih-Wen Lin; John J Rux; E John Wherry; Gary cohen; Roselyn J Eisenberg; Hildegund C J Ertl
Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses.
Nature medicine 2008;14(2):205-12.
2007: Surojit Sarkar; Volker Teichgräber; Vandana Kalia; Antonio Polley; David Masopust; Laurie E Harrington; Rafi Ahmed; E John Wherry
Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6704-14.
2007: David Masopust; Vaiva Vezys; E John Wherry; Rafi Ahmed
A brief history of CD8 T cells.
European journal of immunology 2007;37 Suppl 1():S103-10.
2007: alison crawford; E John Wherry
Inhibitory receptors: whose side are they on?
Nature immunology 2007;8(11):1201-3.
2007: E John Wherry; Sang-Jun Ha; Susan M Kaech; W Nicholas Haining; Surojit Sarkar; Vandana Kalia; Shruti Subramaniam; Joseph N Blattman; Daniel L Barber; Rafi Ahmed
Molecular signature of CD8+ T cell exhaustion during chronic viral infection.
Immunity 2007;27(4):670-84.
2007: Nia Tatsis; Julie C Fitzgerald; Arturo Reyes-Sandoval; Kimberly C Harris-McCoy; Scott E Hensley; Dongming Zhou; Shih-Wen Lin; Ang Bian; Zhi Q Xiang; Amaya Iparraguirre; Cesar Lopez-Camacho; E John Wherry; Hildegund C J Ertl
Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines.
Blood 2007;110(6):1916-23.
2007: Andrew M Intlekofer; Naofumi Takemoto; Charlly Kao; Arnob Banerjee; Felix Schambach; John K Northrop; Hao Shen; E John Wherry; Steven L Reiner
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.
The Journal of experimental medicine 2007;204(9):2015-21.
2007: Susan M Kaech; E John Wherry
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection.
Immunity 2007;27(3):393-405.
2007: Haina Shin; E John Wherry
CD8 T cell dysfunction during chronic viral infection.
Current opinion in immunology 2007;19(4):408-15.
2007: Haina Shin; Shawn D Blackburn; Joseph N Blattman; E John Wherry
Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection.
The Journal of experimental medicine 2007;204(4):941-9.
2007: Shawn D Blackburn; E John Wherry
IL-10, T cell exhaustion and viral persistence.
Trends in microbiology 2007;15(4):143-6.
2007: Arlene H Sharpe; E John Wherry; Rafi Ahmed; Gordon J Freeman
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection.
Nature immunology 2007;8(3):239-45.
2007: Henry Radziewicz; Chris C Ibegbu; Marina L Fernandez; Kimberly A Workowski; Kamil Obideen; Mohammad Wehbi; Holly L Hanson; James P Steinberg; David Masopust; E John Wherry; John D Altman; Barry T Rouse; Gordon J Freeman; Rafi Ahmed; Arash Grakoui
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression.
Journal of virology 2007;81(6):2545-53.
2006: Naofumi Takemoto; Andrew M Intlekofer; John T Northrup; E John Wherry; Steven L Reiner
Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):7515-9.
2006: Shane Crotty; Megan M McCausland; Rachael D Aubert; E John Wherry; Rafi Ahmed
Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease.
Blood 2006;108(9):3085-93.
2006: Gordon J Freeman; E John Wherry; Rafi Ahmed; Arlene H Sharpe
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade.
The Journal of experimental medicine 2006;203(10):2223-7.
2006: E John Wherry; Cheryl L Day; Rika Draenert; Joseph D Miller; Photini Kiepiela; Tonia Woodberry; Christian Brander; Marylyn M Addo; Paul Klenerman; Rafi Ahmed; Bruce D Walker
HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory.
Virology 2006;353(2):366-73.
2006: Cheryl L Day; Daniel E Kaufmann; Photini Kiepiela; Julia A Brown; Eshia Moodley; Sharon Reddy; Elizabeth W Mackey; Joseph D Miller; Alasdair Leslie; Chantal DePierres; Zenele Mncube; Jaikumar Duraiswamy; Baogong Zhu; Quentin Eichbaum; Marcus Altfeld; E John Wherry; Hoosen M Coovadia; Philip J R Goulder; Paul Klenerman; Rafi Ahmed; Gordon J Freeman; Bruce D Walker
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Nature 2006;443(7109):350-4.
2006: E John Wherry; Tatiana N Golovina; Susan E Morrison; Gomathinayagam Sinnathamby; Michael J McElhaugh; David C Shockey; Laurence C Eisenlohr
Re-evaluating the generation of a "proteasome-independent" MHC class I-restricted CD8 T cell epitope.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2249-61.
2006: David Masopust; Vaiva Vezys; E John Wherry; Daniel L Barber; Rafi Ahmed
Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2079-83.
2006: Daniel L Barber; E John Wherry; David Masopust; Baogong Zhu; James P Allison; Arlene H Sharpe; Gordon J Freeman; Rafi Ahmed
Restoring function in exhausted CD8 T cells during chronic viral infection.
Nature 2006;439(7077):682-7.
2005: Andrew M Intlekofer; Naofumi Takemoto; E John Wherry; Sarah A Longworth; John T Northrup; Vikram R Palanivel; Alan C Mullen; Christopher R Gasink; Susan M Kaech; Joseph D Miller; Laurent Gapin; Kenneth Ryan; Andreas P Russ; Tullia Lindsten; Jordan S Orange; Ananda W Goldrath; Rafi Ahmed; Steven L Reiner
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.
Nature immunology 2005;6(12):1236-44.
2005: E John Wherry; Joseph N Blattman; Rafi Ahmed
Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination.
Journal of virology 2005;79(14):8960-8.
2005: J D Miller; David Masopust; E John Wherry; Susan M Kaech; Guido Silvestri; Rafi Ahmed
Differentiation of CD8 T cells in response to acute and chronic viral infections: implications for HIV vaccine development.
Current drug targets. Infectious disorders 2005;5(2):121-9.
2005: Todd C Becker; Shana M Coley; E John Wherry; Rafi Ahmed
Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1269-73.
2004: E John Wherry; Daniel L Barber; Susan M Kaech; Joseph N Blattman; Rafi Ahmed
Antigen-independent memory CD8 T cells do not develop during chronic viral infection.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(45):16004-9.
2004: Tania S Gourley; E John Wherry; David Masopust; Rafi Ahmed
Generation and maintenance of immunological memory.
Seminars in immunology 2004;16(5):323-33.
2004: E John Wherry; Rafi Ahmed
Memory CD8 T-cell differentiation during viral infection.
Journal of virology 2004;78(11):5535-45.
2004: Zhengqi Wu; Margaret Roberts; Melissa Porter; Fabianne Walker; E John Wherry; John Kelly; Massimo Gadina; Elisabeth M Silva; George A DosReis; Marcela F Lopes; John O'Shea; Warren J Leonard; Rafi Ahmed; Richard Siegel
Viral FLIP impairs survival of activated T cells and generation of CD8+ T cell memory.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6313-23.
2004: David Masopust; Susan M Kaech; E John Wherry; Rafi Ahmed
The role of programming in memory T-cell development.
Current opinion in immunology 2004;16(2):217-25.
2004: Manas Mandal; Kim S Kawamura; E John Wherry; Rafi Ahmed; Kyung-Dall Lee
Cytosolic delivery of viral nucleoprotein by listeriolysin O-liposome induces enhanced specific cytotoxic T lymphocyte response and protective immunity.
Molecular pharmaceutics 2004;1(1):2-8.
2003: Susan M Kaech; Joyce T Tan; E John Wherry; Bogumila T Konieczny; Charles D Surh; Rafi Ahmed
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.
Nature immunology 2003;4(12):1191-8.
2003: Robbert van der Most; Kaja Murali-Krishna; J Gibson Lanier; E John Wherry; Maryann T Puglielli; Joseph N Blattman; Alessandro Sette; Rafi Ahmed
Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation.
Virology 2003;315(1):93-102.
2003: Daniel L Barber; E John Wherry; Rafi Ahmed
Cutting edge: rapid in vivo killing by memory CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):27-31.
2003: Andrew B Adams; Matthew A Williams; Thomas R Jones; Nozomu Shirasugi; Megan M Durham; Susan M Kaech; E John Wherry; Thandi M Onami; J Gibson Lanier; Kenneth E Kokko; Thomas C Pearson; Rafi Ahmed; Christian P Larsen
Heterologous immunity provides a potent barrier to transplantation tolerance.
The Journal of clinical investigation 2003;111(12):1887-95.
2003: Ellen N Kersh; Susan M Kaech; Thandi M Onami; Miriana Moran; E John Wherry; M Carrie Miceli; Rafi Ahmed
TCR signal transduction in antigen-specific memory CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5455-63.
2003: Joseph N Blattman; Jason M Grayson; E John Wherry; Susan M Kaech; Kendall A Smith; Rafi Ahmed
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo.
Nature medicine 2003;9(5):540-7.
2003: E John Wherry; Joseph N Blattman; Kaja Murali-Krishna; Robbert van der Most; Rafi Ahmed
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.
Journal of virology 2003;77(8):4911-27.
2003: E John Wherry; Volker Teichgräber; Todd C Becker; David Masopust; Susan M Kaech; Rustom Antia; Ulrich H von Andrian; Rafi Ahmed
Lineage relationship and protective immunity of memory CD8 T cell subsets.
Nature immunology 2003;4(3):225-34.
2002: Jason M Grayson; Laurie E Harrington; J Gibson Lanier; E John Wherry; Rafi Ahmed
Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3760-70.
2002: Todd C Becker; E John Wherry; David Boone; Kaja Murali-Krishna; Rustom Antia; Averil Ma; Rafi Ahmed
Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells.
The Journal of experimental medicine 2002;195(12):1541-8.
2002: E John Wherry; Michael J McElhaugh; Laurence C Eisenlohr
Generation of CD8(+) T cell memory in response to low, high, and excessive levels of epitope.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4455-61.
2002: Susan M Kaech; E John Wherry; Rafi Ahmed
Effector and memory T-cell differentiation: implications for vaccine development.
Nature reviews. Immunology 2002;2(4):251-62.
2002: Tatiana N Golovina; E John Wherry; Timothy N J Bullock; Laurence C Eisenlohr
Efficient and qualitatively distinct MHC class I-restricted presentation of antigen targeted to the endoplasmic reticulum.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2667-75.
2002: E John Wherry; Todd C Becker; David Boone; Murali-Krishna Kaja; Averil Ma; Rafi Ahmed
Homeostatic proliferation but not the generation of virus specific memory CD8 T cells is impaired in the absence of IL-15 or IL-15Ralpha.
Advances in experimental medicine and biology 2002;512():165-75.
2001: E John Wherry; D Rajagopal; Laurence C Eisenlohr
Use of vaccinia virus expression vectors to investigate antigen processing and presentation.
Methods in molecular biology (Clifton, N.J.) 2001;156():89-109.
1999: E John Wherry; KA Puorro; A Porgador; Laurence C Eisenlohr
The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3735-45.
1997: AJ Yellen-Shaw; E John Wherry; G C Dubois; Laurence C Eisenlohr
Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3227-34.