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Diana Whitaker-Menezes

Research Profile

Physiology

Chemicals & Drugs

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Mouse

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Anatomy

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TOP 3
Joseph M Curry; Benjamin Leiby; Michael P Lisanti; Julie A Ames; Archana Anantharaman; Aileen Butera; David M Cognetti; Federica Sotgia; Madalina Tuluc; Diana Whitaker-Menezes; Ubaldo E Martinez-Outschoorn
Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer.
Paola Avena; Ivan Casaburi; James Hulit; Rebecca S Lamb; Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Sebastiano Andò; Wanda Anselmo; Chenguang Wang; Diana Whitaker-Menezes; Federica Sotgia
Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis.
Ahmed F Salem; Marina Sartini; Federica Sotgia; Diana Whitaker-Menezes; Ubaldo E Martinez-Outschoorn; Mazhar Salim Al-Zoubi; Generoso Bevilacqua; Ferruccio Galbiati; Ricardo Gandara; Anthony Howell; James Hulit; Rebecca Lamb; Michael P Lisanti
Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.

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All Publications

2013: Joseph M Curry; Benjamin Leiby; Michael P Lisanti; Julie A Ames; Archana Anantharaman; Aileen Butera; David M Cognetti; Federica Sotgia; Madalina Tuluc; Diana Whitaker-Menezes; Ubaldo E Martinez-Outschoorn
Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer.
Cell cycle (Georgetown, Tex.) 2013;12(9):1371-84.
2013: Paola Avena; Ivan Casaburi; James Hulit; Rebecca S Lamb; Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Sebastiano Andò; Wanda Anselmo; Chenguang Wang; Diana Whitaker-Menezes; Federica Sotgia
Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis.
Cell cycle (Georgetown, Tex.) 2013;12(9):1360-70.
2013: Ahmed F Salem; Marina Sartini; Federica Sotgia; Diana Whitaker-Menezes; Ubaldo E Martinez-Outschoorn; Mazhar Salim Al-Zoubi; Generoso Bevilacqua; Ferruccio Galbiati; Ricardo Gandara; Anthony Howell; James Hulit; Rebecca Lamb; Michael P Lisanti
Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.
Cell cycle (Georgetown, Tex.) 2013;12(5):818-25.
2013: Mazhar Al-Zoubi; Hwyda A Arafat; Generoso Bevilacqua; Ricardo Gandara; Anthony Howell; James Hulit; Rebecca Lamb; Ubaldo E Martinez-Outschoorn; Ahmed F Salem; Marina Sartini; Federica Sotgia; Diana Whitaker-Menezes; Michael P Lisanti
Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo.
Cell cycle (Georgetown, Tex.) 2013;12(3):480-90.
2012: Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Sharon Sneddon; Federica Sotgia; Diana Whitaker-Menezes; Renee Balliet; Ruth Birbe; Alessandro Bombonati; Anthony Howell; Rebecca Lamb; Zhao Lin; Michael P Lisanti
BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.
Cell cycle (Georgetown, Tex.) 2012;11(23):4402-13.
2012: Federica Sotgia; Aristotelis Tsirigos; Diana Whitaker-Menezes; Ubaldo E Martinez-Outschoorn; Ahmed F Salem; Sharon Sneddon; Anthony Howell; James Hulit; Rebecca Lamb; Michael P Lisanti
Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells.
Cell cycle (Georgetown, Tex.) 2012;11(23):4390-401.
2012: Ahmed F Salem; Federica Sotgia; Diana Whitaker-Menezes; Anthony Howell; Michael P Lisanti
Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance.
Cell cycle (Georgetown, Tex.) 2012;11(22):4174-80.
2012: Ubaldo E Martinez-Outschoorn; Federica Sotgia; Diana Whitaker-Menezes; Renee M Balliet; Anthony Howell; Zhao Lin; Michael P Lisanti
Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma.
Cell cycle (Georgetown, Tex.) 2012;11(22):4152-66.
2012: Ubaldo E Martinez-Outschoorn; Federica Sotgia; Diana Whitaker-Menezes; Anthony Howell; Zhao Lin; Michael P Lisanti
Ketone body utilization drives tumor growth and metastasis.
Cell cycle (Georgetown, Tex.) 2012;11(21):3964-71.
2012: Ubaldo E Martinez-Outschoorn; Anthony Howell; Zhao Lin; Michael P Lisanti; Diana Whitaker-Menezes; Federica Sotgia
Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.
Cell cycle (Georgetown, Tex.) 2012;11(21):3956-63.
2012: Gloria Bonuccelli; Franco Capozza; Remedios Castello-Cros; Anthony Howell; Zhao Lin; Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Aristotelis Tsirigos; Diana Whitaker-Menezes; Jiao Xuanmao; Federica Sotgia
The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis.
Cell cycle (Georgetown, Tex.) 2012;11(21):3972-82.
2012: Claudia Capparelli; Barbara Chiavarina; Anthony Howell; James Hulit; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Timothy G Pestell; Federica Sotgia; Diana Whitaker-Menezes; Sebastiano Andò; Michael P Lisanti
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.
Cell cycle (Georgetown, Tex.) 2012;11(19):3599-610.
2012: Valentina Carito; Maria Cristina Caroleo; Erika Cione; Anthony Howell; Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Gloria Bonuccelli; Diana Whitaker-Menezes; Federica Sotgia
Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth.
Cell cycle (Georgetown, Tex.) 2012;11(18):3403-14.
2012: Barbara Chiavarina; Anthony Howell; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Federica Sotgia; Herbert B Tanowitz; Diana Whitaker-Menezes; Michael P Lisanti
Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells.
Cell cycle (Georgetown, Tex.) 2012;11(17):3280-9.
2012: Carmela Guido; Anthony Howell; Zhao Lin; Sebastiano Andò; Saveria Aquila; Renee Balliet; Claudia Capparelli; Ubaldo Martinez-Outschoorn; Richard G Pestell; Federica Sotgia; Diana Whitaker-Menezes; Michael P Lisanti
Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.
Cell cycle (Georgetown, Tex.) 2012;11(16):3019-35.
2012: Carmela Guido; Anthony Howell; Zhao Lin; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Federica Sotgia; Diana Whitaker-Menezes; Teresa A Zimmers; Sebastiano Ando'; Saveria Aquila; Mathew C Casimiro; Michael P Lisanti
Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.
Oncotarget 2012;3(8):798-810.
2012: Ahmed F Salem; Federica Sotgia; Herbert B Tanowitz; Diana Whitaker-Menezes; Ubaldo E Martinez-Outschoorn; Mazhar Salim Al-Zoubi; Anthony Howell; Zhao Lin; Richard G Pestell; Michael P Lisanti
Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells.
Cell cycle (Georgetown, Tex.) 2012;11(13):2545-56.
2012: Isabelle Mercier; Janet N Milliman; Alexander Molchansky; Richard G Pestell; Kevin Quann; Roland Schwarting; Federica Sotgia; Kanani Titchen; Diana Whitaker-Menezes; Mikhail V Blagosklonny; Kelly G Bryant; Jeanette Camacho; Donna M Gonzales; Jean-François Jasmin; Michael P Lisanti
Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug.
The American journal of pathology 2012;181(1):278-93.
2012: Claudia Capparelli; Carmela Guido; Anthony Howell; Michael P Lisanti; Ubaldo Martinez-Outschoorn; Richard G Pestell; Timothy G Pestell; Sharon Sneddon; Renee Balliet; Diana Whitaker-Menezes; Federica Sotgia
CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.
Cell cycle (Georgetown, Tex.) 2012;11(12):2272-84.
2012: Claudia Capparelli; Allison F Goldberg; Carmela Guido; Anthony Howell; Ubaldo Martinez-Outschoorn; Richard G Pestell; Timothy G Pestell; Sharon Sneddon; Federica Sotgia; Aristotelis Tsirigos; Diana Whitaker-Menezes; Renee Balliet; Ruth Birbe; Gloria Bonuccelli; Michael P Lisanti
Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.
Cell cycle (Georgetown, Tex.) 2012;11(12):2285-302.
2012: Stephanos Pavlides; Richard G Pestell; Sharon Sneddon; Federica Sotgia; Iset Vera; Diana Whitaker-Menezes; Ricardo Gandara; Anthony Howell; Ubaldo E Martinez-Outschoorn; Isabelle Mercier; Michael P Lisanti
Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis.
Antioxidants & redox signaling 2012;16(11):1264-84.
2012: Franco Capozza; Remedios Castello-Cros; Marco Crosariol; Antonia Follenzi; SANJAY kATIYAR; Gemma Llaverias; Richard G Pestell; Federica Sotgia; Casey Trimmer; Diana Whitaker-Menezes; Michael P Lisanti
Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration.
Cancer research 2012;72(9):2262-74.
2012: Federica Sotgia; Diana Whitaker-Menezes; Agnieszka Witkiewicz; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Nancy J Philp; Ruth C Birbe; Neal Flomenberg; Anthony Howell; Michael P Lisanti
Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.
Cell cycle (Georgetown, Tex.) 2012;11(7):1445-54.
2012: Agnieszka Witkiewicz; Abhijit Dasgupta; Ricardo Gandara; Zhao Lin; Ubaldo E Martinez-Outschoorn; Nancy J Philp; Sharon Sneddon; Federica Sotgia; Diana Whitaker-Menezes; Michael P Lisanti
Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.
Cell cycle (Georgetown, Tex.) 2012;11(6):1108-17.
2012: Adam Ertel; Anthony Howell; Ruth C Birbe; Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Richard G Pestell; Federica Sotgia; Aristotelis Tsirigos; Diana Whitaker-Menezes; Michael P Lisanti
Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism.
Cell cycle (Georgetown, Tex.) 2012;11(2):253-63.
2011: Barbara Chiavarina; Rene Daniel; Anthony Howell; Ubaldo E Martinez-Outschoorn; Richard G Pestell; Johanna Smith; Federica Sotgia; Diana Whitaker-Menezes; Agnieszka Witkiewicz; Ruth Birbe; Michael P Lisanti
Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
Cancer biology & therapy 2011;12(12):1101-13.
2011: Gongyi Ren; Jean-Baptiste Roullet; Robert D Steiner; G Stephen Tint; Diana Whitaker-Menezes; Yi Xie; Robert H Cox; Paul Dimuzio; Philippe G Frank; Robert F Jacob; Yuri Kaulin; Michael P Lisanti; R Preston Mason; Louise S Merkens; Thomas N Tulenko
Alterations in membrane caveolae and BKCa channel activity in skin fibroblasts in Smith-Lemli-Opitz syndrome.
Molecular genetics and metabolism 2011;104(3):346-55.
2011: Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Richard G Pestell; Anthony Howell; Zhao Lin; Diana Whitaker-Menezes; Federica Sotgia
Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer".
Cell cycle (Georgetown, Tex.) 2011;10(15):2440-9.
2011: Remedios Castello-Cros; Renato V Iozzo; David P Beason; Alex Molchansky; George Purkins; Louis J Soslowsky; Federica Sotgia; Diana Whitaker-Menezes; Michael P Lisanti
Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis.
Cell cycle (Georgetown, Tex.) 2011;10(13):2140-50.
2011: Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Richard G Pestell; Anthony Howell; Diana Whitaker-Menezes; Federica Sotgia
Accelerated aging in the tumor microenvironment: connecting aging, inflammation and cancer metabolism with personalized medicine.
Cell cycle (Georgetown, Tex.) 2011;10(13):2059-63.
2011: Remedios Castello-Cros; Anthony Howell; Ruth C Birbe; Franco Capozza; Alex Molchansky; Richard G Pestell; Federica Sotgia; Diana Whitaker-Menezes; Agnieszka Witkiewicz; Gloria Bonuccelli; Michael P Lisanti
Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis.
Cell cycle (Georgetown, Tex.) 2011;10(12):2021-34.
2011: Ubaldo E Martinez-Outschoorn; Richard G Pestell; Diana Whitaker-Menezes; Neal Flomenberg; Anthony Howell; Zhao Lin; Michael P Lisanti; Federica Sotgia
Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator.
Cell cycle (Georgetown, Tex.) 2011;10(11):1784-93.
2011: Diana Whitaker-Menezes; Agnieszka Witkiewicz; Ruth C Birbe; Adam Ertel; Neal Flomenberg; Ricardo Gandara; Anthony Howell; Zhao Lin; Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Richard G Pestell; Nancy J Philp; Federica Sotgia; Michael P Lisanti
Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.
Cell cycle (Georgetown, Tex.) 2011;10(11):1772-83.
2011: Ellina Cheskis Feiner; Paul Chung; Jean Francois Jasmin; Jin Zhang; Diana Whitaker-Menezes; Valerie Myers; Jianliang Song; Elizabeth W Feldman; Hajime Funakoshi; Brent R Degeorge; Rao V Yelamarty; Walter J Koch; Michael P Lisanti; Charles F McTiernan; Joseph Y Cheung; Michael R Bristow; Tung O Chan; Arthur M Feldman
Left ventricular dysfunction in murine models of heart failure and in failing human heart is associated with a selective decrease in the expression of caveolin-3.
Journal of cardiac failure 2011;17(3):253-63.
2011: Casey Trimmer; Federica Sotgia; Diana Whitaker-Menezes; Renee M Balliet; Gregory Eaton; Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Anthony Howell; Renato V Iozzo; Richard G Pestell; Philipp E Scherer; Franco Capozza; Michael P Lisanti
Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.
Cancer biology & therapy 2011;11(4):383-94.
2010: Ubaldo E Martinez-Outschoorn; Diana Whitaker-Menezes; Stephanos Pavlides; Barbara Chiavarina; Gloria Bonuccelli; Trimmer Casey; Aristotelis Tsirigos; Gemma Migneco; Agnieszka Witkiewicz; Renee Balliet; Isabelle Mercier; Chengwang Wang; Neal Flomenberg; Anthony Howell; Zhao Lin; Jaime Caro; Richard G Pestell; Federica Sotgia; Michael P Lisanti
The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox.
Cell cycle (Georgetown, Tex.) 2010;9(21):4297-306.
2010: Casey Trimmer; Diana Whitaker-Menezes; Gloria Bonuccelli; Janet N Milliman; Kristin M Daumer; Andrew E Aplin; Richard G Pestell; Federica Sotgia; Michael P Lisanti; Franco Capozza
CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.
Cancer research 2010;70(19):7489-99.
2010: Michael P Lisanti; Ubaldo E Martinez-Outschoorn; Barbara Chiavarina; Stephanos Pavlides; Diana Whitaker-Menezes; Aristotelis Tsirigos; Agnieszka Witkiewicz; Zhao Lin; Renee Balliet; Anthony Howell; Federica Sotgia
Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment.
Cancer biology & therapy 2010;10(6):537-42.
2010: Barbara Chiavarina; Diana Whitaker-Menezes; Gemma Migneco; Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Anthony Howell; Herbert B Tanowitz; Mathew C Casimiro; Chenguang Wang; Richard G Pestell; Philip Grieshaber; Jaime Caro; Federica Sotgia; Michael P Lisanti
HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis.
Cell cycle (Georgetown, Tex.) 2010;9(17):3534-51.
2010: Stephanos Pavlides; Aristotelis Tsirigos; Gemma Migneco; Diana Whitaker-Menezes; Barbara Chiavarina; Neal Flomenberg; Philippe G Frank; Mathew C Casimiro; Chenguang Wang; Richard G Pestell; Ubaldo E Martinez-Outschoorn; Anthony Howell; Federica Sotgia; Michael P Lisanti
The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism.
Cell cycle (Georgetown, Tex.) 2010;9(17):3485-505.
2010: Ubaldo E Martinez-Outschoorn; Casey Trimmer; Zhao Lin; Diana Whitaker-Menezes; Barbara Chiavarina; Jie Zhou; Chengwang Wang; Stephanos Pavlides; Maria P Martinez-Cantarin; Franco Capozza; Agnieszka Witkiewicz; Neal Flomenberg; Anthony Howell; Richard G Pestell; Jaime Caro; Michael P Lisanti; Federica Sotgia
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.
Cell cycle (Georgetown, Tex.) 2010;9(17):3515-33.
2010: Gloria Bonuccelli; Aristotelis Tsirigos; Diana Whitaker-Menezes; Stephanos Pavlides; Richard G Pestell; Barbara Chiavarina; Philippe G Frank; Neal Flomenberg; Anthony Howell; Ubaldo E Martinez-Outschoorn; Federica Sotgia; Michael P Lisanti
Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism.
Cell cycle (Georgetown, Tex.) 2010;9(17):3506-14.
2010: Ubaldo E Martinez-Outschoorn; Renee M Balliet; Dayana B Rivadeneira; Barbara Chiavarina; Stephanos Pavlides; Chenguang Wang; Diana Whitaker-Menezes; Kristin M Daumer; Zhao Lin; Agnieszka Witkiewicz; Neal Flomenberg; Anthony Howell; Richard G Pestell; Erik S Knudsen; Federica Sotgia; Michael P Lisanti
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
Cell cycle (Georgetown, Tex.) 2010;9(16):3256-76.
2010: Gemma Migneco; Diana Whitaker-Menezes; Barbara Chiavarina; Remedios Castello-Cros; Stephanos Pavlides; Richard G Pestell; Alessandro Fatatis; Neal Flomenberg; Aristotelis Tsirigos; Anthony Howell; Ubaldo E Martinez-Outschoorn; Federica Sotgia; Michael P Lisanti
Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling.
Cell cycle (Georgetown, Tex.) 2010;9(12):2412-22.
2010: Ubaldo E Martinez-Outschoorn; Stephanos Pavlides; Diana Whitaker-Menezes; Kristin M Daumer; Janet N Milliman; Barbara Chiavarina; Gemma Migneco; Agnieszka Witkiewicz; Maria P Martinez-Cantarin; Neal Flomenberg; Anthony Howell; Richard G Pestell; Michael P Lisanti; Federica Sotgia
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors.
Cell cycle (Georgetown, Tex.) 2010;9(12):2423-33.
2010: Gloria Bonuccelli; Diana Whitaker-Menezes; Remedios Castello-Cros; Stephanos Pavlides; Richard G Pestell; Alessandro Fatatis; Agnieszka Witkiewicz; Matthew G Vander Heiden; Gemma Migneco; Barbara Chiavarina; Philippe G Frank; Franco Capozza; Neal Flomenberg; Ubaldo E Martinez-Outschoorn; Federica Sotgia; Michael P Lisanti
The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts.
Cell cycle (Georgetown, Tex.) 2010;9(10):1960-71.
2009: Stephanos Pavlides; Diana Whitaker-Menezes; Remedios Castello-Cros; Neal Flomenberg; Agnieszka Witkiewicz; Philippe G Frank; Mathew C Casimiro; Chenguang Wang; Paolo Fortina; Sankar Addya; Richard G Pestell; Ubaldo E Martinez-Outschoorn; Federica Sotgia; Michael P Lisanti
The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.
Cell cycle (Georgetown, Tex.) 2009;8(23):3984-4001.
2009: Jie Zhou; Wei Zhang; Bing Liang; Mathew C Casimiro; Diana Whitaker-Menezes; Min Wang; Michael P Lisanti; Susan Lanza-Jacoby; Richard G Pestell; Chenguang Wang
PPARgamma activation induces autophagy in breast cancer cells.
The international journal of biochemistry & cell biology 2009;41(11):2334-42.
2009: Federica Sotgia; francesco del galdo; Mathew C Casimiro; Gloria Bonuccelli; Isabelle Mercier; Diana Whitaker-Menezes; Kristin M Daumer; Jie Zhou; Chenguang Wang; Sanjay Katiyar; Huan Xu; Emily Bosco; Andrew A Quong; Bruce Aronow; Agnieszka Witkiewicz; Carlo Minetti; Philippe G Frank; Sergio A Jimenez; Erik S Knudsen; Richard G Pestell; Michael P Lisanti
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
The American journal of pathology 2009;174(3):746-61.
2009: Federica Sotgia; Mathew C Casimiro; Gloria Bonuccelli; Manran Liu; Diana Whitaker-Menezes; Ozlem Er; Kristin M Daumer; Isabelle Mercier; Agnieszka K Witkiewicz; Carlo Minetti; Franco Capozza; Michael Gormley; Andrew A Quong; Hallgeir Rui; Philippe G Frank; Janet N Milliman; Erik S Knudsen; Jie Zhou; Chenguang Wang; Richard G Pestell; Michael P Lisanti
Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation.
The American journal of pathology 2009;174(2):613-29.
2007: Donna Brennan; Ying Hu; Sohaila Joubeh; Yoo Won Choi; Diana Whitaker-Menezes; Thomas G O'Brien; Jouni Uitto; Ulrich Rodeck; My G Mahoney
Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes.
Journal of cell science 2007;120(Pt 5):758-71.
2007: Qian Zhan; Sabina Signoretti; Diana Whitaker-Menezes; Thea M Friedman; Robert Korngold; George F Murphy
Cytokeratin15-positive basal epithelial cells targeted in graft-versus-host disease express a constitutive antiapoptotic phenotype.
The Journal of investigative dermatology 2007;127(1):106-15.
2006: Fani Segev; Elise Héon; William G Cole; Richard J Wenstrup; Felix Young; Allan R Slomovic; David S Rootman; Diana Whitaker-Menezes; Inna Chervoneva; David E Birk
Structural abnormalities of the cornea and lid resulting from collagen V mutations.
Investigative ophthalmology & visual science 2006;47(2):565-73.
2004: Swati Choksi; Judith C Kim; Diana Whitaker-Menezes; George F Murphy; Thea M Friedman; Robert Korngold
A CD8 DE loop peptide analog prevents graft-versus-host disease in a multiple minor histocompatibility antigen-mismatched bone marrow transplantation model.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(10):669-80.
2003: Masatoshi Deguchi; Diana Whitaker-Menezes; Stephen C Jones; Setsuya Aiba; Satoshi Nakagawa; Hachiro Tagami; Robert Korngold; George F Murphy
12E2: a cloned murine dermal cell with features of dermal dendrocytes and capacity to produce pathologic changes resembling early Kaposi's sarcoma.
The American journal of pathology 2003;163(5):1817-25.
2003: Diana Whitaker-Menezes; Stephen C Jones; Thea M Friedman; Robert Korngold; George F Murphy
An epithelial target site in experimental graft-versus-host disease and cytokine-mediated cytotoxicity is defined by cytokeratin 15 expression.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2003;9(9):559-70.
2002: Judith C Kim; Diana Whitaker-Menezes; Masatoshi Deguchi; Brigette S Adair; Robert Korngold; George F Murphy
Novel expression of vascular cell adhesion molecule-1 (CD106) by squamous epithelium in experimental acute graft-versus-host disease.
The American journal of pathology 2002;161(3):763-70.
2001: Hirohiko Sueki; Diana Whitaker-Menezes; Albert M Kligman
Structural diversity of mast cell granules in black and white skin.
The British journal of dermatology 2001;144(1):85-93.
2000: MR Monteiro; E E Murphy; N A Galaria; Diana Whitaker-Menezes; George F Murphy
Cytological alterations in dermal dendrocytes in vitro: evidence for transformation to a non-dendritic phenotype.
The British journal of dermatology 2000;143(1):84-90.
1999: S Heinonen; M Männikkö; John F Klement; Diana Whitaker-Menezes; George F Murphy; Jouni Uitto
Targeted inactivation of the type VII collagen gene (Col7a1) in mice results in severe blistering phenotype: a model for recessive dystrophic epidermolysis bullosa.
Journal of cell science 1999;112 ( Pt 21)():3641-8.
1998: Y H Yoo; B S Park; Diana Whitaker-Menezes; Robert Korngold; George F Murphy
Dermal dendrocytes participate in the cellular pathology of experimental acute graft-versus-host disease.
Journal of cutaneous pathology 1998;25(8):426-34.
1998: Christine L Egan; M J Viglione-Schneck; Laurence Walsh; B Green; John Q Trojanowski; Diana Whitaker-Menezes; George F Murphy
Characterization of unmyelinated axons uniting epidermal and dermal immune cells in primate and murine skin.
Journal of cutaneous pathology 1998;25(1):20-9.
1997: PJ Roosje; Diana Whitaker-Menezes; M H Goldschmidt; Peter F Moore; Ton Willemse; George F Murphy
Feline atopic dermatitis. A model for Langerhans cell participation in disease pathogenesis.
The American journal of pathology 1997;151(4):927-32.
1997: Melpo Christofidou-Solomidou; B Jack Longley; Diana Whitaker-Menezes; Steven M Albelda; George F Murphy
Human skin/SCID mouse chimeras as an in vivo model for human cutaneous mast cell hyperplasia.
The Journal of investigative dermatology 1997;109(1):102-7.
1997: PJ Koch; My G Mahoney; H Ishikawa; Leena Pulkkinen; Jouni Uitto; L Shultz; George F Murphy; Diana Whitaker-Menezes; John R Stanley
Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris.
The Journal of cell biology 1997;137(5):1091-102.
1997: Y H Yoo; Anita Gilliam; Diana Whitaker-Menezes; Robert Korngold; George F Murphy
Experimental induction and ultrastructural characterization of apoptosis in murine acute cutaneous graft-versus-host disease.
Archives of dermatological research 1997;289(7):389-98.
1996: Anita Gilliam; Diana Whitaker-Menezes; R Korngold; George F Murphy
Apoptosis is the predominant form of epithelial target cell injury in acute experimental graft-versus-host disease.
The Journal of investigative dermatology 1996;107(3):377-83.
1996: S B Dietz; Diana Whitaker-Menezes; Stuart R Lessin
The role of alpha E beta 7 integrin (CD103) and E-cadherin in epidermotropism in cutaneous T-cell lymphoma.
Journal of cutaneous pathology 1996;23(4):312-8.
1995: Diana Whitaker-Menezes; Norman M Schechter; George F Murphy
Serine proteinases are regionally segregated within mast cell granules.
Laboratory investigation; a journal of technical methods and pathology 1995;72(1):34-41.
1995: R R Weiss; Diana Whitaker-Menezes; J Longley; J Bender; George F Murphy
Human dermal endothelial cells express membrane-associated mast cell growth factor.
The Journal of investigative dermatology 1995;104(1):101-6.