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Anne White

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Ram P Narayanan; Robert L Oliver; Martin K Rutter; Kirk W Siddals; Anne White; Robert R Davies; Paul Durrington; Matthew Gittins; Julie E Hudson; J Martin Gibson
Atorvastatin administration is associated with dose-related changes in IGF bioavailability.
Anne White
Do we all feel we succeed despite the system?
Rachel Stovold; Fiona H Blackhall; Caroline Dive; JianMei Hou; Suzanne Meredith; Anne White
Biomarkers for small cell lung cancer: neuroendocrine, epithelial and circulating tumour cells.

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2013: Ram P Narayanan; Robert L Oliver; Martin K Rutter; Kirk W Siddals; Anne White; Robert R Davies; Paul Durrington; Matthew Gittins; Julie E Hudson; J Martin Gibson
Atorvastatin administration is associated with dose-related changes in IGF bioavailability.
European journal of endocrinology / European Federation of Endocrine Societies 2013;168(4):543-8.
2012: Anne White
Do we all feel we succeed despite the system?
Endocrine-related cancer 2012;19(4):P9-P12.
2012: Rachel Stovold; Fiona H Blackhall; Caroline Dive; JianMei Hou; Suzanne Meredith; Anne White
Biomarkers for small cell lung cancer: neuroendocrine, epithelial and circulating tumour cells.
Lung cancer (Amsterdam, Netherlands) 2012;76(3):263-8.
2012: Ghazala Begum; Frank Bloomfield; John R G Challis; Kristin Connor; Emma Bolton Smith; Adam Stevens; Anne White
Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinning.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(4):1694-703.
2011: George Schlossmacher; Adam Stevens; Anne White
Glucocorticoid receptor-mediated apoptosis: mechanisms of resistance in cancer cells.
The Journal of endocrinology 2011;211(1):17-25.
2011: Adam Stevens; Ghazala Begum; Anne White
Epigenetic changes in the hypothalamic pro-opiomelanocortin gene: a mechanism linking maternal undernutrition to obesity in the offspring?
European journal of pharmacology 2011;660(1):194-201.
2011: P G Murray; A Read; I Banerjee; Andrew J Whatmore; Lynn E Pritchard; R A Davies; John Brennand; Anne White; R J M Ross; Peter E Clayton
Reduced appetite and body mass index with delayed puberty in a mother and son: association with a rare novel sequence variant in the leptin gene.
European journal of endocrinology / European Federation of Endocrine Societies 2011;164(4):521-7.
2011: Paul Kay; Laura Matthews; George Schlossmacher; Dave Singh; Paula Sommer; Anne White; David Ray
Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells.
PloS one 2011;6(10):e24839.
2010: Erika Harno; Anne White
Will treating diabetes with 11β-HSD1 inhibitors affect the HPA axis?
Trends in endocrinology and metabolism: TEM 2010;21(10):619-27.
2010: Adam Stevens; Ghazala Begum; Alice Cook; Kristin Connor; Christopher Rumball; Mark Oliver; John Challis; Frank Bloomfield; Anne White
Epigenetic changes in the hypothalamic proopiomelanocortin and glucocorticoid receptor genes in the ovine fetus after periconceptional undernutrition.
Endocrinology 2010;151(8):3652-64.
2010: Paula Sommer; Rachel L Cowen; Andrew Berry; Ann Cookson; Brian A Telfer; Kaye J Williams; Ian J Stratford; Paul Kay; Anne White; David W Ray
Glucocorticoid receptor over-expression promotes human small cell lung cancer apoptosis in vivo and thereby slows tumor growth.
Endocrine-related cancer 2010;17(1):203-13.
2010: Adam Stevens; Anne White
ACTH: cellular peptide hormone synthesis and secretory pathways.
Results and problems in cell differentiation 2010;50():63-84.
2008: John W M Creemers; Yung Seng Lee; Robert L Oliver; Mithat Bahceci; Alpaslan Tuzcu; Deniz Gokalp; Julia Keogh; Stefan Herber; Anne White; Stephen O'Rahilly; I Sadaf Farooqi
Mutations in the amino-terminal region of proopiomelanocortin (POMC) in patients with early-onset obesity impair POMC sorting to the regulated secretory pathway.
The Journal of clinical endocrinology and metabolism 2008;93(11):4494-9.
2008: Lisa Rice; Charlotte E Waters; Jennifer Eccles; Helen Garside; Paula Sommer; Paul Kay; Fiona H Blackhall; Leo Zeef; Brian Telfer; Ian Stratford; Rob Clarke; Dave Singh; Adam Stevens; Anne White; David W Ray
Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor.
The Journal of endocrinology 2008;198(3):499-509.
2007: A Gyte; Lynn E Pritchard; H B Jones; John Brennand; Anne White
Reduced expression of the KATP channel subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of Zucker diabetic fatty rats.
Journal of neuroendocrinology 2007;19(12):941-51.
2007: P Sommer; Philippe Le Rouzic; H Gillingham; A Berry; M Kayahara; T Huynh; Anne White; David W Ray
Glucocorticoid receptor overexpression exerts an antisurvival effect on human small cell lung cancer cells.
Oncogene 2007;26(50):7111-21.
2007: Lynn E Pritchard; Anne White
Neuropeptide processing and its impact on melanocortin pathways.
Endocrinology 2007;148(9):4201-7.
2007: Karine Rousseau; Söbia Kauser; Lynn E Pritchard; Anne Warhurst; Robert L Oliver; Andrzej Slominski; Edward T Wei; Anthony J Thody; Desmond J Tobin; Anne White
Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1844-56.
2006: Helen Garside; Charlotte Waters; Andy Berry; Lisa Rice; Helen C Ardley; Anne White; Philip A Robinson; David Ray
UbcH7 interacts with the glucocorticoid receptor and mediates receptor autoregulation.
The Journal of endocrinology 2006;190(3):621-9.
2006: John W M Creemers; Lynn E Pritchard; Amy Gyte; Philippe Le Rouzic; Sandra Meulemans; Sharon L Wardlaw; Xiaorong Zhu; Donald F Steiner; Nicola Davies; Duncan Armstrong; Catherine B Lawrence; Simon M Luckman; Catherine A Schmitz; Rick A Davies; John Brennand; Anne White
Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3.
Endocrinology 2006;147(4):1621-31.
2005: Lynn E Pritchard; Anne White
Agouti-related protein: more than a melanocortin-4 receptor antagonist?
Peptides 2005;26(10):1759-70.
2004: C E Waters; Adam Stevens; Anne White; David W Ray
Analysis of co-factor function in a glucocorticoid-resistant small cell carcinoma cell line.
The Journal of endocrinology 2004;183(2):375-83.
2004: Hedley A Coppock; Anne White; John D Aplin; Melissa Westwood
Matrix metalloprotease-3 and -9 proteolyze insulin-like growth factor-binding protein-1.
Biology of reproduction 2004;71(2):438-43.
2004: Lynn E Pritchard; D Armstrong; N Davies; Robert L Oliver; C A Schmitz; John Brennand; G F Wilkinson; Anne White
Agouti-related protein (83-132) is a competitive antagonist at the human melanocortin-4 receptor: no evidence for differential interactions with pro-opiomelanocortin-derived ligands.
The Journal of endocrinology 2004;180(1):183-91.
2003: Adam Stevens; Helen Garside; Andy Berry; Charlotte Waters; Anne White; David Ray
Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):845-59.
2003: Lynn E Pritchard; Robert L Oliver; Julie D McLoughlin; Susan Birtles; Catherine B Lawrence; Andrew Turnbull; Anne White
Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balance.
Endocrinology 2003;144(3):760-6.
2003: Emma Marshman; Kirsty A Green; David J Flint; Anne White; Charles H Streuli; Melissa Westwood
Insulin-like growth factor binding protein 5 and apoptosis in mammary epithelial cells.
Journal of cell science 2003;116(Pt 4):675-82.
2003: Robert L Oliver; Julian R E Davis; Anne White
Characterisation of ACTH related peptides in ectopic Cushing's syndrome.
Pituitary 2003;6(3):119-26.
2002: Kirk W Siddals; Melissa Westwood; J Martin Gibson; Anne White
IGF-binding protein-1 inhibits IGF effects on adipocyte function: implications for insulin-like actions at the adipocyte.
The Journal of endocrinology 2002;174(2):289-97.
2002: Adrian H Heald; Kirk W Siddals; William Fraser; William Taylor; Kalpana Kaushal; Julie Morris; Robert J Young; Anne White; J Martin Gibson
Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes.
Diabetes 2002;51(8):2629-36.
2002: Lynn E Pritchard; Andrew Turnbull; Anne White
Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signalling and obesity.
The Journal of endocrinology 2002;172(3):411-21.
2002: T T Huynh; David W Ray; Iain J Brogan; Adam Stevens; Julian R E Davis; Anne White; A White
Failure of steroid regulation of the MMTV promoter in a small cell lung cancer cell line is caused by a DNA sequence flanking the glucocorticoid response element.
The Journal of endocrinology 2002;172(2):295-302.
2001: Melissa Westwood; John D Aplin; I A Collinge; A Gill; Anne White; J Martin Gibson
alpha 2-Macroglobulin: a new component in the insulin-like growth factor/insulin-like growth factor binding protein-1 axis.
The Journal of biological chemistry 2001;276(45):41668-74.
2001: J Kennedy Cruickshank; Adrian H Heald; S Anderson; Janet Cade; James N Sampayo; Lisa Riste; Alyson Greenhalgh; William Taylor; William Fraser; Anne White; J Martin Gibson
Epidemiology of the insulin-like growth factor system in three ethnic groups.
American journal of epidemiology 2001;154(6):504-13.
2001: Adrian H Heald; J Kennedy Cruickshank; Lisa Riste; Janet Cade; S Anderson; Alyson Greenhalgh; James N Sampayo; William Taylor; William Fraser; Anne White; J Martin Gibson
Close relation of fasting insulin-like growth factor binding protein-1 (IGFBP-1) with glucose tolerance and cardiovascular risk in two populations.
Diabetologia 2001;44(3):333-9.
2001: J Martin Gibson; John D Aplin; Anne White; Melissa Westwood
Regulation of IGF bioavailability in pregnancy.
Molecular human reproduction 2001;7(1):79-87.
2000: Anne White; David W Ray; A Talbot; P Abraham; Anthony J Thody; J S Bevan
Cushing's syndrome due to phaeochromocytoma secreting the precursors of adrenocorticotropin.
The Journal of clinical endocrinology and metabolism 2000;85(12):4771-5.
2000: Adrian H Heald; Peter L Selby; Anne White; J Martin Gibson
Progestins abrogate estrogen-induced changes in the insulin-like growth factor axis.
American journal of obstetrics and gynecology 2000;183(3):593-600.
1999: Iain J Brogan; I A Murray; G Cerillo; Michael G Needham; Anne White; Julian R E Davis
Interaction of glucocorticoid receptor isoforms with transcription factors AP-1 and NF-kappaB: lack of effect of glucocorticoid receptor beta.
Molecular and cellular endocrinology 1999;157(1-2):95-104.
1999: David W Ray; C S Suen; Andrew Brass; Joanne Soden; Anne White
Structure/function of the human glucocorticoid receptor: tyrosine 735 is important for transactivation.
Molecular endocrinology (Baltimore, Md.) 1999;13(11):1855-63.
1999: Melissa Westwood; J Martin Gibson; LA Pennells; Anne White
Modification of plasma insulin-like growth factors and binding proteins during oral contraceptive use and the normal menstrual cycle.
American journal of obstetrics and gynecology 1999;180(3 Pt 1):530-6.
1999: J Martin Gibson; Melissa Westwood; Finn Friis Lauszus; Joachim G Klebe; Allan Flyvbjerg; Anne White
Phosphorylated insulin-like growth factor binding protein 1 is increased in pregnant diabetic subjects.
Diabetes 1999;48(2):321-6.
1998: H E Wilson; Anne White
Prohormones: their clinical relevance.
Trends in endocrinology and metabolism: TEM 1998;9(10):396-402.
1998: Marcelo J Perone; C A Murray; O A Brown; S Gibson; Anne White; EA Linton; A V Perkins; Pedro R Lowenstein; Maria G Castro
Procorticotrophin-releasing hormone: endoproteolytic processing and differential release of its derived peptides within AtT20 cells.
Molecular and cellular endocrinology 1998;142(1-2):191-202.
1998: Anne White; S Gibson
ACTH precursors: biological significance and clinical relevance.
Clinical endocrinology 1998;48(3):251-5.
1997: Melissa Westwood; J Martin Gibson; Anne White
Purification and characterization of the insulin-like growth factor-binding protein-1 phosphoform found in normal plasma.
Endocrinology 1997;138(3):1130-6.
1996: D W Ray; Julian R E Davis; Anne White; Adrian J L Clark
Glucocorticoid receptor structure and function in glucocorticoid-resistant small cell lung carcinoma cells.
Cancer research 1996;56(14):3276-80.
1996: S Gibson; D W Ray; S R Crosby; T L Dornan; A M Jennings; J S Bevan; Julian R E Davis; Anne White
Impaired processing of proopiomelanocortin in corticotroph macroadenomas.
The Journal of clinical endocrinology and metabolism 1996;81(2):497-502.
1995: Melissa Westwood; J Martin Gibson; A C Williams; Peter E Clayton; O Hamberg; Allan Flyvbjerg; Anne White
Hormonal regulation of circulating insulin-like growth factor-binding protein-1 phosphorylation status.
The Journal of clinical endocrinology and metabolism 1995;80(12):3520-7.
1995: D W Ray; S Gibson; S R Crosby; D Davies; Julian R E Davis; Anne White
Elevated levels of adrenocorticotropin (ACTH) precursors in post-adrenalectomy Cushing's disease and their regulation by glucocorticoids.
The Journal of clinical endocrinology and metabolism 1995;80(8):2430-6.
1995: C Tsigos; S Gibson; S R Crosby; Anne White; R J Young
Cerebrospinal fluid levels of beta endorphin in painful and painless diabetic polyneuropathy.
Journal of diabetes and its complications 1995;9(2):92-6.
1995: J Martin Gibson; Melissa Westwood; S R Crosby; C Gordon; J M Holly; W Fraser; C Anderson; Anne White; R J Young
Choice of treatment affects plasma levels of insulin-like growth factor-binding protein-1 in noninsulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1995;80(4):1369-75.
1994: Melissa Westwood; J Martin Gibson; A J Davies; R J Young; Anne White
The phosphorylation pattern of insulin-like growth factor-binding protein-1 in normal plasma is different from that in amniotic fluid and changes during pregnancy.
The Journal of clinical endocrinology and metabolism 1994;79(6):1735-41.
1994: D W Ray; A C Littlewood; Adrian J L Clark; Julian R E Davis; Anne White
Human small cell lung cancer cell lines expressing the proopiomelanocortin gene have aberrant glucocorticoid receptor function.
The Journal of clinical investigation 1994;93(4):1625-30.
1994: S Gibson; S R Crosby; M F Stewart; A M Jennings; E McCall; Anne White
Differential release of proopiomelanocortin-derived peptides from the human pituitary: evidence from a panel of two-site immunoradiometric assays.
The Journal of clinical endocrinology and metabolism 1994;78(4):835-41.
1993: S Gibson; S R Crosby; Anne White
Discrimination between beta-endorphin and beta-lipotrophin in human plasma using two-site immunoradiometric assays.
Clinical endocrinology 1993;39(4):445-53.
1993: E C Crowne; W H Wallace; S Gibson; C M Moore; Anne White; Stephen M Shalet
Adrenocorticotrophin and cortisol secretion in children after low dose cranial irradiation.
Clinical endocrinology 1993;39(3):297-305.
1993: Anne White; Adrian J L Clark
The cellular and molecular basis of the ectopic ACTH syndrome.
Clinical endocrinology 1993;39(2):131-41.
1993: C Tsigos; P Reed; C Weinkove; Anne White; R J Young
Plasma norepinephrine in sensory diabetic polyneuropathy.
Diabetes care 1993;16(5):722-7.
1993: S R Crosby; C D Anderton; Melissa Westwood; J M Holly; S C Cwyfan Hughes; M Gibson; C A Morrison; R J Young; Anne White
Measurement of insulin-like growth factor-II in human plasma using a specific monoclonal antibody-based two-site immunoradiometric assay.
The Journal of endocrinology 1993;137(1):141-50.
1993: C Tsigos; S R Crosby; S Gibson; R J Young; Anne White
Proopiomelanocortin is the predominant adrenocorticotropin-related peptide in human cerebrospinal fluid.
The Journal of clinical endocrinology and metabolism 1993;76(3):620-4.
1993: C Tsigos; R J Young; Anne White
Diabetic neuropathy is associated with increased activity of the hypothalamic-pituitary-adrenal axis.
The Journal of clinical endocrinology and metabolism 1993;76(3):554-8.
1993: C Tsigos; L T Diemel; Anne White; D R Tomlinson; R J Young
Cerebrospinal fluid levels of substance P and calcitonin-gene-related peptide: correlation with sural nerve levels and neuropathic signs in sensory diabetic polyneuropathy.
Clinical science (London, England : 1979) 1993;84(3):305-11.
1993: W E Farrell; M F Stewart; Adrian J L Clark; S R Crosby; Julian R E Davis; Anne White
Glucocorticoid inhibition of ACTH peptides: small cell lung cancer cell lines are more resistant than pituitary corticotroph adenoma cells.
Journal of molecular endocrinology 1993;10(1):25-32.
1992: S R Crosby; C Tsigos; C D Anderton; C Gordon; R J Young; Anne White
Elevated plasma insulin-like growth factor binding protein-1 levels in type 1 (insulin-dependent) diabetic patients with peripheral neuropathy.
Diabetologia 1992;35(9):868-72.
1992: W E Farrell; Adrian J L Clark; M F Stewart; S R Crosby; Anne White
Bromocriptine inhibits pro-opiomelanocortin mRNA and ACTH precursor secretion in small cell lung cancer cell lines.
The Journal of clinical investigation 1992;90(3):705-10.
1992: S Al-Damluji; Anne White
Central noradrenergic lesion impairs the adrenocorticotrophin response to release of endogenous catecholamines.
Journal of neuroendocrinology 1992;4(3):319-23.
1992: C Tsigos; Anne White; R J Young
Discrimination between painful and painless diabetic neuropathy based on testing of large somatic nerve and sympathetic nerve function.
Diabetic medicine : a journal of the British Diabetic Association 1992;9(4):359-65.
1991: W H Wallace; E C Crowne; Stephen M Shalet; C Moore; S Gibson; M D Littley; Anne White
Episodic ACTH and cortisol secretion in normal children.
Clinical endocrinology 1991;34(3):215-21.
1991: Nancy J Rothwell; A Hardwick; R A LeFeuvre; S R Crosby; Anne White
Central actions of CRF on thermogenesis are mediated by pro-opiomelanocortin products.
Brain research 1991;541(1):89-92.
1990: S al-Damluji; Anne White; M Besser
Brattleboro rats have deficient adrenocorticotropin responses to activation of central alpha 1-adrenoceptors.
Endocrinology 1990;127(6):2849-53.
1990: S R Crosby; M F Stewart; W E Farrell; S Gibson; Anne White
Comparison of ACTH and ACTH precursor peptides secreted by human pituitary and lung tumour cells in vitro.
The Journal of endocrinology 1990;125(1):147-52.
1990: S al-Damluji; R Thomas; Anne White; M Besser
Vasopressin mediates alpha 1-adrenergic stimulation of adrenocorticotropin secretion.
Endocrinology 1990;126(4):1989-95.
1990: Adrian J L Clark; M F Stewart; P M Lavender; W Farrell; S R Crosby; L H Rees; Anne White
Defective glucocorticoid regulation of proopiomelanocortin gene expression and peptide secretion in a small cell lung cancer cell line.
The Journal of clinical endocrinology and metabolism 1990;70(2):485-90.
1990: R Mitchell; A Lambert; S R Crosby; Anne White; WR Robertson
ACTH adrenal cell bioassay: improved sensitivity (12 ng/L) achieved by immunoextraction of ACTH from human plasma by a monoclonal antibody.
Annals of clinical biochemistry 1990;27 ( Pt 1)():59-64.
1990: S al-Damluji; P Bouloux; Anne White; M Besser
The role of alpha-2-adrenoceptors in the control of ACTH secretion; interaction with the opioid system.
Neuroendocrinology 1990;51(1):76-81.
1989: M D Littley; S Gibson; Anne White; Stephen M Shalet
Comparison of the ACTH and cortisol responses to provocative testing with glucagon and insulin hypoglycaemia in normal subjects.
Clinical endocrinology 1989;31(5):527-33.
1989: S Gibson; A Pollock; M Littley; Stephen M Shalet; Anne White
Advantages of IRMA over RIA in the measurement of ACTH.
Annals of clinical biochemistry 1989;26 ( Pt 6)():500-7.
1989: M F Stewart; S R Crosby; S Gibson; P R Twentyman; Anne White
Small cell lung cancer cell lines secrete predominantly ACTH precursor peptides not ACTH.
British journal of cancer 1989;60(1):20-4.
1989: Anne White; M F Stewart; W E Farrell; S R Crosby; P M Lavender; P R Twentyman; L H Rees; Adrian J L Clark
Pro-opiomelanocortin gene expression and peptide secretion in human small-cell lung cancer cell lines.
Journal of molecular endocrinology 1989;3(1):65-70.
1989: S H Dobson; S Gibson; Anne White
Assessment of the potency of different standards in the immunoradiometric assay of ACTH.
Annals of clinical biochemistry 1989;26 ( Pt 1)():96-101.
1988: S R Crosby; M F Stewart; J G Ratcliffe; Anne White
Direct measurement of the precursors of adrenocorticotropin in human plasma by two-site immunoradiometric assay.
The Journal of clinical endocrinology and metabolism 1988;67(6):1272-7.