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Michael White

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Sabrina Semprini; Michael R H White; Amanda Patist; Adriano G Rossi; Raheela Awais; Julian R E Davis; Ian Dransfield; Karen Featherstone; Claire V Harper; Anne V McNamara; Alan S McNeilly; Judith R McNeilly; John J Mullins
Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model.
Yunjiao Wang; Michael R H White; Hong Yue; Caroline A Horton; Douglas B Kell; Mark R Muldoon; Pawel Paszek; David S Broomhead
A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation.
Luke W Thomas; Michael R H White; Richard E Clark; Connie Lam; Robert J Moots; David G Spiller; Steven W Edwards
Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.

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All Publications

2012: Sabrina Semprini; Michael R H White; Amanda Patist; Adriano G Rossi; Raheela Awais; Julian R E Davis; Ian Dransfield; Karen Featherstone; Claire V Harper; Anne V McNamara; Alan S McNeilly; Judith R McNeilly; John J Mullins
Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model.
Endocrinology 2012;153(6):2724-34.
2012: Yunjiao Wang; Michael R H White; Hong Yue; Caroline A Horton; Douglas B Kell; Mark R Muldoon; Pawel Paszek; David S Broomhead
A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation.
Journal of theoretical biology 2012;297():137-47.
2012: Luke W Thomas; Michael R H White; Richard E Clark; Connie Lam; Robert J Moots; David G Spiller; Steven W Edwards
Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.
PloS one 2012;7(9):e45088.
2011: Karen Featherstone; Claire V Harper; Anne McNamara; Alan S McNeilly; Judith McNeilly; John J Mullins; Sabrina Semprini; David G Spiller; Michael R H White; Julian R E Davis
Pulsatile patterns of pituitary hormone gene expression change during development.
Journal of cell science 2011;124(Pt 20):3484-91.
2011: Gerard F Powell; Mark C Prescott; Fergus G P Earley; Janet Phillips; David G Spiller; Phillip C Turner; Deborah A Ward; Michael R H White; Huw H Rees
The molecular action of the novel insecticide, Pyridalyl.
Insect biochemistry and molecular biology 2011;41(7):459-69.
2011: Claire V Harper; Bärbel Finkenstädt; Dan J Woodcock; Sönke Friedrichsen; Sabrina Semprini; Louise Ashall; David G Spiller; John J Mullins; David A Rand; Julian R E Davis; Michael R H White
Dynamic analysis of stochastic transcription cycles.
PLoS biology 2011;9(4):e1000607.
2010: Cheng-Jin Du; Marco Marcello; David G Spiller; Michael R H White; Till Bretschneider
Interactive segmentation of clustered cells via geodesic commute distance and constrained density weighted Nyström method.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2010;77(12):1137-47.
2010: Marco Marcello; Michael R H White
Spatial and temporal information coding and noise in the NF-κB system.
Biochemical Society transactions 2010;38(5):1247-50.
2010: David A Turner; Pawel Paszek; Dan J Woodcock; David E Nelson; Caroline A Horton; Yunjiao Wang; David G Spiller; David A Rand; Michael R H White; Claire V Harper
Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells.
Journal of cell science 2010;123(Pt 16):2834-43.
2010: Pawel Paszek; Sheila Ryan; Louise Ashall; Kate Sillitoe; Claire V Harper; David G Spiller; David A Rand; Michael R H White
Population robustness arising from cellular heterogeneity.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(25):11644-9.
2010: David G Spiller; Christopher D Wood; David A Rand; Michael R H White
Measurement of single-cell dynamics.
Nature 2010;465(7299):736-45.
2010: Claire V Harper; Karen Featherstone; Sabrina Semprini; Sönke Friedrichsen; Judith McNeilly; Pawel Paszek; David G Spiller; Alan S McNeilly; John J Mullins; Julian R E Davis; Michael R H White
Dynamic organisation of prolactin gene expression in living pituitary tissue.
Journal of cell science 2010;123(Pt 3):424-30.
2009: Violaine Sée; Paul Free; Yann Cesbron; Paola Nativo; Umbreen Shaheen; Daniel J Rigden; David G Spiller; David G Fernig; Michael R H White; Ian Prior; Mathias Brust; Brahim Lounis; Raphaël Lévy
Cathepsin L digestion of nanobioconjugates upon endocytosis.
ACS nano 2009;3(9):2461-8.
2009: Michael R H White; David G Spiller
Is frequency-encoding of information a major theme in cellular processes?
Cell cycle (Georgetown, Tex.) 2009;8(17):2677-8.
2009: Louise Ashall; Caroline A Horton; David E Nelson; Pawel Paszek; Claire V Harper; Kate Sillitoe; Sheila Ryan; David G Spiller; John Unitt; David S Broomhead; Douglas B Kell; David A Rand; Violaine Sée; Michael R H White
Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription.
Science (New York, N.Y.) 2009;324(5924):242-6.
2009: Sabrina Semprini; Sonke Friedrichsen; Claire V Harper; Judith R McNeilly; Antony D Adamson; David G Spiller; N Kotelevtseva; Gillian Brooker; David G Brownstein; Alan S McNeilly; Michael R H White; Julian R E Davis; John J Mullins
Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model.
Molecular endocrinology (Baltimore, Md.) 2009;23(4):529-38.
2009: Daniel Jameson; David A Turner; John Ankers; Stephnie Kennedy; Sheila Ryan; Neil Swainston; Tony Griffiths; David G Spiller; Stephen G Oliver; Michael R H White; Douglas B Kell; Norman W Paton
Information management for high content live cell imaging.
BMC bioinformatics 2009;10():226.
2008: Bärbel F Finkenstädt; Elizabeth A Heron; Michal Komorowski; Kieron Edwards; Sanyi Tang; Claire V Harper; Julian R E Davis; Michael R H White; Andrew J Millar; David A Rand
Reconstruction of transcriptional dynamics from gene reporter data using differential equations.
Bioinformatics (Oxford, England) 2008;24(24):2901-7.
2008: Claire V Harper; Joanne A Cummerson; Michael R H White; Stephen Publicover; Peter M Johnson
Dynamic resolution of acrosomal exocytosis in human sperm.
Journal of cell science 2008;121(Pt 13):2130-5.
2008: A D Adamson; S Friedrichsen; S Semprini; C V Harper; John J Mullins; Michael R H White; Julian R E Davis
Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-alpha signaling.
Endocrinology 2008;149(2):687-94.
2007: Stephen R Pennington; Brian J Foster; Shaun R Hawley; Rosalind E Jenkins; Olga Zolle; Michael R H White; Christine J McNamee; Peter Sheterline; Alec W M Simpson
Cell shape-dependent Control of Ca2+ influx and cell cycle progression in Swiss 3T3 fibroblasts.
The Journal of biological chemistry 2007;282(44):32112-20.
2007: Dale A Moulding; Michael P Blundell; David G Spiller; Michael R H White; Giles O Cory; Yolanda Calle; Helena Kempski; Joanna Sinclair; Phil J Ancliff; Christine Kinnon; Gareth E Jones; Adrian J Thrasher
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia.
The Journal of experimental medicine 2007;204(9):2213-24.
2007: Arjuna Ratnayaka; Luminita Paraoan; David G Spiller; Paul Hiscott; Glyn Nelson; Michael R H White; Ian Grierson
A dual Golgi- and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility.
Experimental eye research 2007;84(6):1135-9.
2007: K Sillitoe; C Horton; David G Spiller; Michael R H White
Single-cell time-lapse imaging of the dynamic control of NF-kappaB signalling.
Biochemical Society transactions 2007;35(Pt 2):263-6.
2007: Arjuna Ratnayaka; Luminita Paraoan; Glyn Nelson; David G Spiller; Michael R H White; Paul Hiscott
Trafficking of osteonectin by retinal pigment epithelial cells: evidence for basolateral secretion.
The international journal of biochemistry & cell biology 2007;39(1):85-92.
2006: Hailin Shen; Glyn Nelson; David E Nelson; Stephnie Kennedy; David G Spiller; Tony Griffiths; Norman Paton; Stephen G Oliver; Michael R H White; Douglas B Kell
Automated tracking of gene expression in individual cells and cell compartments.
Journal of the Royal Society, Interface / the Royal Society 2006;3(11):787-94.
2006: Sönke Friedrichsen; Claire V Harper; Sabrina Semprini; Michael Wilding; Antony D Adamson; Dave G Spiller; Glyn Nelson; John J Mullins; Michael R H White; Julian R E Davis
Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling.
Endocrinology 2006;147(2):773-81.
2005: A E C Ihekwaba; David S Broomhead; Rachel L Grimley; Neil Benson; Michael R H White; D B Kell
Synergistic control of oscillations in the NF-kappaB signalling pathway.
Systems biology 2005;152(3):153-60.
2004: D E Nelson; Violaine Sée; Glyn Nelson; Michael R H White
Oscillations in transcription factor dynamics: a new way to control gene expression.
Biochemical Society transactions 2004;32(Pt 6):1090-2.
2004: Luminita Paraoan; Arjuna Ratnayaka; David G Spiller; Paul Hiscott; Michael R H White; Ian Grierson
Unexpected intracellular localization of the AMD-associated cystatin C variant.
Traffic (Copenhagen, Denmark) 2004;5(11):884-95.
2004: D E Nelson; A E C Ihekwaba; M Elliott; J R Johnson; C A Gibney; B E Foreman; Glyn Nelson; Violaine See; C A Horton; David G Spiller; Steven W Edwards; H P McDowell; John Unitt; Elaine Sullivan; Rachel L Grimley; Neil Benson; David S Broomhead; D B Kell; Michael R H White
Oscillations in NF-kappaB signaling control the dynamics of gene expression.
Science (New York, N.Y.) 2004;306(5696):704-8.
2004: Violaine Sée; Nina K M Rajala; David G Spiller; Michael R H White
Calcium-dependent regulation of the cell cycle via a novel MAPK--NF-kappaB pathway in Swiss 3T3 cells.
The Journal of cell biology 2004;166(5):661-72.
2003: Carolyn J Ruddell; Geoffrey Wainwright; Audrey Geffen; Michael R H White; Simon G Webster; Huw H Rees
Cloning, characterization, and developmental expression of a putative farnesoic acid O-methyl transferase in the female edible crab Cancer pagurus.
The Biological bulletin 2003;205(3):308-18.
2003: Jonathan D Johnston; J Anne Stirland; Michael R H White; Julian R E Davis; Andrew S I Loudon
Heterogeneous regulation of individual lactotroph cells by photoperiod in the Syrian hamster (Mesocricetus auratus).
General and comparative endocrinology 2003;134(2):182-6.
2003: Giancarlo A Biagini; Patrick G Bray; David G Spiller; Michael R H White; Stephen A Ward
The digestive food vacuole of the malaria parasite is a dynamic intracellular Ca2+ store.
The Journal of biological chemistry 2003;278(30):27910-5.
2003: J Anne Stirland; ZC Seymour; S Windeatt; AJ Norris; P Stanley; Maria G Castro; Andrew S I Loudon; Michael R H White; Julian R E Davis
Real-time imaging of gene promoter activity using an adenoviral reporter construct demonstrates transcriptional dynamics in normal anterior pituitary cells.
The Journal of endocrinology 2003;178(1):61-9.
2003: Glyn Nelson; Geraint Wilde; David G Spiller; Stephnie M Kennedy; David W Ray; Elaine Sullivan; John Unitt; Michael R H White
NF-kappaB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms.
Journal of cell science 2003;116(Pt 12):2495-503.
2003: Jonathan D Johnston; Felino R A Cagampang; J Anne Stirland; Amanda-Jayne F Carr; Michael R H White; Julian R E Davis; Andrew S I Loudon
Evidence for an endogenous per1- and ICER-independent seasonal timer in the hamster pituitary gland.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(8):810-5.
2003: Gianluca Fossati; Dale A Moulding; David G Spiller; Robert J Moots; Michael R H White; Steven W Edwards
The mitochondrial network of human neutrophils: role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1964-72.
2003: AJ Norris; J Anne Stirland; D W McFerran; ZC Seymour; D G Spiller; Andrew S I Loudon; Michael R H White; Julian R E Davis
Dynamic patterns of growth hormone gene transcription in individual living pituitary cells.
Molecular endocrinology (Baltimore, Md.) 2003;17(2):193-202.
2003: P-J M Noble; Geraint Wilde; Michael R H White; Steven R Pennington; Graham J Dockray; Andrea Varro
Stimulation of gastrin-CCKB receptor promotes migration of gastric AGS cells via multiple paracrine pathways.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(1):G75-84.
2002: Glyn Nelson; Geraint Wilde; David G Spiller; Elaine Sullivan; John Unitt; Michael R H White
Dynamic analysis of STAT6 signalling in living cells.
FEBS letters 2002;532(1-2):188-92.
2002: David G Spiller; Patrick G Bray; Ruth H Hughes; Stephen A Ward; Michael R H White
The pH of the Plasmodium falciparum digestive vacuole: holy grail or dead-end trail?
Trends in parasitology 2002;18(10):441-4.
2002: Glyn Nelson; Luminita Paraoan; David G Spiller; Geraint Wilde; Mark A Browne; Peter K Djali; John Unitt; Elaine Sullivan; Eike Floettmann; Michael R H White
Multi-parameter analysis of the kinetics of NF-kappaB signalling and transcription in single living cells.
Journal of cell science 2002;115(Pt 6):1137-48.
2002: Patrick G Bray; Kevin Saliba; Jill D Davies; David G Spiller; Michael R H White; Kiaran Kirk; Stephen A Ward
Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH.
Molecular and biochemical parasitology 2002;119(2):301-4; discussion 307-9, 311-3.
2001: Luminita Paraoan; Michael R H White; David G Spiller; Ian Grierson; B Edward H Maden
Precursor cystatin C in cultured retinal pigment epithelium cells: evidence for processing through the secretory pathway.
Molecular membrane biology 2001;18(3):229-36.
2001: D W McFerran; J Anne Stirland; AJ Norris; R A Khan; N Takasuka; ZC Seymour; M S Gill; WR Robertson; Andrew S I Loudon; Julian R E Davis; Michael R H White
Persistent synchronized oscillations in prolactin gene promoter activity in living pituitary cells.
Endocrinology 2001;142(7):3255-60.
2001: J Anne Stirland; Jonathan D Johnston; Felino R A Cagampang; P J Morgan; Maria G Castro; Michael R H White; Julian R E Davis; Andrew S I Loudon
Photoperiodic regulation of prolactin gene expression in the Syrian hamster by a pars tuberalis-derived factor.
Journal of neuroendocrinology 2001;13(2):147-57.
2000: Dale A Moulding; RV Giles; David G Spiller; Michael R H White; David M Tidd; Steven W Edwards
Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells.
Blood 2000;96(5):1756-63.
2000: Cahit Akgul; Dale A Moulding; Michael R H White; Steven W Edwards
In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins.
FEBS letters 2000;478(1-2):72-6.
2000: Cahit Akgul; P C Turner; Michael R H White; Steven W Edwards
Functional analysis of the human MCL-1 gene.
Cellular and molecular life sciences : CMLS 2000;57(4):684-91.
1998: N Takasuka; Michael R H White; CD Wood; WR Robertson; Julian R E Davis
Dynamic changes in prolactin promoter activation in individual living lactotrophic cells.
Endocrinology 1998;139(3):1361-8.