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Stephen White

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Chemicals & Drugs

Occupations

Thermodynamics

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Physiology

Protein Folding

Phenomena

Procedures

Fluorescence Spectrometry

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Network (preview)

Co-Publications
Name
19
Wimley, William
18
Ladokhin, Alexey
12
Hristova, Kalina
8
Selsted, Michael
7
Tobias, Douglas
5
Jayasinghe, Sajith
4
von Heijne, Gunnar
3
Benz, Ryan
3
Castro-Román, Francisco
3
Gawrisch, Klaus
2
Fernández-Vidal, Mónica
2
Freites, Alfredo
2
Creamer, Trevor
1
Collier, Robert
1
Tran, Dat

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Publications

TOP 3
Jaud Simon; Fernández-Vidal Mónica; Nilsson Ingmarie; Meindl-Beinker Nadja M; Hübner Nadja C; Tobias Douglas J; von Heijne Gunnar; White Stephen H
Insertion of short transmembrane helices by the Sec61 translocon.
Sasaki Hirotaka; White Stephen H
A novel fluorescent probe that senses the physical state of lipid bilayers.
White Stephen H
Biophysical dissection of membrane proteins.

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All Publications

2009: Jaud Simon; Fernández-Vidal Mónica; Nilsson Ingmarie; Meindl-Beinker Nadja M; Hübner Nadja C; Tobias Douglas J; von Heijne Gunnar; White Stephen H
Insertion of short transmembrane helices by the Sec61 translocon.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(28):11588-93.
2009: Sasaki Hirotaka; White Stephen H
A novel fluorescent probe that senses the physical state of lipid bilayers.
Biophysical journal 2009;96(11):4631-41.
2009: White Stephen H
Biophysical dissection of membrane proteins.
Nature 2009;459(7245):344-6.
2009: Sasaki Hirotaka; Arai Hiromi; Cocco Melanie J; White Stephen H
pH dependence of sphingosine aggregation.
Biophysical journal 2009;96(7):2727-33.
2009: Bondar Ana-Nicoleta; del Val Coral; White Stephen H
Rhomboid protease dynamics and lipid interactions.
Structure (London, England : 1993) 2009;17(3):395-405.
2008: Sasaki Hirotaka; White Stephen H
Aggregation behavior of an ultra-pure lipopolysaccharide that stimulates TLR-4 receptors.
Biophysical journal 2008;95(2):986-93.
2008: White Stephen H; von Heijne Gunnar
How translocons select transmembrane helices.
Annual review of biophysics 2008;37():23-42.
2007: White Stephen H
Biochemistry. Crowds of syntaxins.
Science (New York, N.Y.) 2007;317(5841):1045-6.
2007: Fernández-Vidal Mónica; Jayasinghe Sajith; Ladokhin Alexey S; White Stephen H
Folding amphipathic helices into membranes: amphiphilicity trumps hydrophobicity.
Journal of molecular biology 2007;370(3):459-70.
2007: White Stephen H
Membrane protein insertion: the biology-physics nexus.
The Journal of general physiology 2007;129(5):363-9.
2007: Gawrisch Klaus; Gaede Holly C; Mihailescu Mihaela; White Stephen H
Hydration of POPC bilayers studied by 1H-PFG-MAS-NOESY and neutron diffraction.
European biophysics journal : EBJ 2007;36(4-5):281-91.
2007: Jaud Simon; Tobias Douglas J; Falke Joseph J; White Stephen H
Self-induced docking site of a deeply embedded peripheral membrane protein.
Biophysical journal 2007;92(2):517-24.
2006: Freites J Alfredo; Tobias Douglas J; White Stephen H
A voltage-sensor water pore.
Biophysical journal 2006;91(11):L90-2.
2006: Castro-Román Francisco; Benz Ryan W; White Stephen H; Tobias Douglas J
Investigation of finite system-size effects in molecular dynamics simulations of lipid bilayers.
The journal of physical chemistry. B 2006;110(47):24157-64.
2006: Benz Ryan W; Nanda Hirsh; Castro-Román Francisco; White Stephen H; Tobias Douglas J
Diffraction-based density restraints for membrane and membrane-peptide molecular dynamics simulations.
Biophysical journal 2006;91(10):3617-29.
2005: Freites J Alfredo; Tobias Douglas J; von Heijne Gunnar; White Stephen H
Interface connections of a transmembrane voltage sensor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):15059-64.
2005: Hristova Kalina; White Stephen H
An experiment-based algorithm for predicting the partitioning of unfolded peptides into phosphatidylcholine bilayer interfaces.
Biochemistry 2005;44(37):12614-9.
2005: Benz Ryan W; Castro-Román Francisco; Tobias Douglas J; White Stephen H
Experimental validation of molecular dynamics simulations of lipid bilayers: a new approach.
Biophysical journal 2005;88(2):805-17.
2005: White Stephen H
How hydrogen bonds shape membrane protein structure.
Advances in protein chemistry 2005;72():157-72.
2004: Wimley William C; White Stephen H
Reversible unfolding of beta-sheets in membranes: a calorimetric study.
Journal of molecular biology 2004;342(3):703-11.
2004: White Stephen H; von Heijne Gunnar
The machinery of membrane protein assembly.
Current opinion in structural biology 2004;14(4):397-404.
2004: Ladokhin Alexey S; Legmann Rachel; Collier R John; White Stephen H
Reversible refolding of the diphtheria toxin T-domain on lipid membranes.
Biochemistry 2004;43(23):7451-8.
2004: Ladokhin Alexey S; White Stephen H
Interfacial folding and membrane insertion of a designed helical peptide.
Biochemistry 2004;43(19):5782-91.
2003: White Stephen H
Translocons, thermodynamics, and the folding of membrane proteins.
FEBS letters 2003;555(1):116-21.
2002: Ladokhin Alexey S; Isas J Mario; Haigler Harry T; White Stephen H
Determining the membrane topology of proteins: insertion pathway of a transmembrane helix of annexin 12.
Biochemistry 2002;41(46):13617-26.
2001: Jayasinghe S; Hristova K; White S H
Energetics, stability, and prediction of transmembrane helices.
Journal of molecular biology 2001;312(5):927-34.
2001: Ladokhin A S; White S H
'Detergent-like' permeabilization of anionic lipid vesicles by melittin.
Biochimica et biophysica acta 2001;1514(2):253-60.
2001: Ladokhin A S; White S H
Alphas and taus of tryptophan fluorescence in membranes.
Biophysical journal 2001;81(3):1825-7.
2001: White S H; Ladokhin A S; Jayasinghe S; Hristova K
How membranes shape protein structure.
The Journal of biological chemistry 2001;276(35):32395-8.
2001: Ladokhin A S; White S H
Protein chemistry at membrane interfaces: non-additivity of electrostatic and hydrophobic interactions.
Journal of molecular biology 2001;309(3):543-52.
2001: Jayasinghe S; Hristova K; White S H
MPtopo: A database of membrane protein topology.
Protein science : a publication of the Protein Society 2001;10(2):455-8.
2001: Hristova K; Dempsey C E; White S H
Structure, location, and lipid perturbations of melittin at the membrane interface.
Biophysical journal 2001;80(2):801-11.
2000: Ladokhin A S; Jayasinghe S; White S H
How to measure and analyze tryptophan fluorescence in membranes properly, and why bother?
Analytical biochemistry 2000;285(2):235-45.
2000: Osapay K; Tran D; Ladokhin A S; White S H; Henschen A H; Selsted M E
Formation and characterization of a single Trp-Trp cross-link in indolicidin that confers protease stability without altering antimicrobial activity.
The Journal of biological chemistry 2000;275(16):12017-22.
2000: Wimley W C; White S H
Designing transmembrane alpha-helices that insert spontaneously.
Biochemistry 2000;39(15):4432-42.
2000: Wimley W C; White S H
Determining the membrane topology of peptides by fluorescence quenching.
Biochemistry 2000;39(1):161-70.
1999: Ladokhin A S; Selsted M E; White S H
CD spectra of indolicidin antimicrobial peptides suggest turns, not polyproline helix.
Biochemistry 1999;38(38):12313-9.
1999: Hristova K; Wimley W C; Mishra V K; Anantharamiah G M; Segrest J P; White S H
An amphipathic alpha-helix at a membrane interface: a structural study using a novel X-ray diffraction method.
Journal of molecular biology 1999;290(1):99-117.
1999: Ladokhin A S; White S H
Folding of amphipathic alpha-helices on membranes: energetics of helix formation by melittin.
Journal of molecular biology 1999;285(4):1363-9.
1999: White S H; Wimley W C
Membrane protein folding and stability: physical principles.
Annual review of biophysics and biomolecular structure 1999;28():319-65.
1998: White S H; Wimley W C
Hydrophobic interactions of peptides with membrane interfaces.
Biochimica et biophysica acta 1998;1376(3):339-52.
1998: Yau W M; Wimley W C; Gawrisch K; White S H
The preference of tryptophan for membrane interfaces.
Biochemistry 1998;37(42):14713-8.
1998: Hristova K; White S H
Determination of the hydrocarbon core structure of fluid dioleoylphosphocholine (DOPC) bilayers by x-ray diffraction using specific bromination of the double-bonds: effect of hydration.
Biophysical journal 1998;74(5):2419-33.
1998: Wimley W C; Hristova K; Ladokhin A S; Silvestro L; Axelsen P H; White S H
Folding of beta-sheet membrane proteins: a hydrophobic hexapeptide model.
Journal of molecular biology 1998;277(5):1091-110.
1998: White S H; Wimley W C; Ladokhin A S; Hristova K
Protein folding in membranes: determining energetics of peptide-bilayer interactions.
Methods in enzymology 1998;295():62-87.
1997: Hristova K; Selsted M E; White S H
Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins.
The Journal of biological chemistry 1997;272(39):24224-33.
1997: Ladokhin A S; Selsted M E; White S H
Sizing membrane pores in lipid vesicles by leakage of co-encapsulated markers: pore formation by melittin.
Biophysical journal 1997;72(4):1762-6.
1997: Ladokhin A S; Selsted M E; White S H
Bilayer interactions of indolicidin, a small antimicrobial peptide rich in tryptophan, proline, and basic amino acids.
Biophysical journal 1997;72(2 Pt 1):794-805.
1997: Ladokhin A S; Wimley W C; Hristova K; White S H
Mechanism of leakage of contents of membrane vesicles determined by fluorescence requenching.
Methods in enzymology 1997;278():474-86.
1996: Wimley W C; White S H
Experimentally determined hydrophobicity scale for proteins at membrane interfaces.
Nature structural biology 1996;3(10):842-8.
1996: Hristova K; Selsted M E; White S H
Interactions of monomeric rabbit neutrophil defensins with bilayers: comparison with dimeric human defensin HNP-2.
Biochemistry 1996;35(36):11888-94.
1996: Wimley W C; Creamer T P; White S H
Solvation energies of amino acid side chains and backbone in a family of host-guest pentapeptides.
Biochemistry 1996;35(16):5109-24.
1996: Wimley W C; Gawrisch K; Creamer T P; White S H
Direct measurement of salt-bridge solvation energies using a peptide model system: implications for protein stability.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2985-90.
1995: Ladokhin A S; Wimley W C; White S H
Leakage of membrane vesicle contents: determination of mechanism using fluorescence requenching.
Biophysical journal 1995;69(5):1964-71.
1995: White S H; Wimley W C; Selsted M E
Structure, function, and membrane integration of defensins.
Current opinion in structural biology 1995;5(4):521-7.
1994: Wimley W C; Selsted M E; White S H
Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores.
Protein science : a publication of the Protein Society 1994;3(9):1362-73.
1994: White S H
The evolution of proteins from random amino acid sequences: II. Evidence from the statistical distributions of the lengths of modern protein sequences.
Journal of molecular evolution 1994;38(4):383-94.
1994: White S H
Global statistics of protein sequences: implications for the origin, evolution, and prediction of structure.
Annual review of biophysics and biomolecular structure 1994;23():407-39.
1993: Wimley W C; White S H
Quantitation of electrostatic and hydrophobic membrane interactions by equilibrium dialysis and reverse-phase HPLC.
Analytical biochemistry 1993;213(2):213-7.
1993: Wimley W C; White S H
Membrane partitioning: distinguishing bilayer effects from the hydrophobic effect.
Biochemistry 1993;32(25):6307-12.
1993: White S H; Jacobs R E
The evolution of proteins from random amino acid sequences. I. Evidence from the lengthwise distribution of amino acids in modern protein sequences.
Journal of molecular evolution 1993;36(1):79-95.
1992: Wimley W C; White S H
Partitioning of tryptophan side-chain analogs between water and cyclohexane.
Biochemistry 1992;31(51):12813-8.
1992: White S H
Amino acid preferences of small proteins. Implications for protein stability and evolution.
Journal of molecular biology 1992;227(4):991-5.
1992: Wiener M C; White S H
Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. III. Complete structure.
Biophysical journal 1992;61(2):434-47.
1992: Wiener M C; White S H
Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. II. Distribution and packing of terminal methyl groups.
Biophysical journal 1992;61(2):428-33.
1991: Wiener M C; King G I; White S H
Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. I. Scaling of neutron data and the distributions of double bonds and water.
Biophysical journal 1991;60(3):568-76.
1991: Wiener M C; White S H
Transbilayer distribution of bromine in fluid bilayers containing a specifically brominated analogue of dioleoylphosphatidylcholine.
Biochemistry 1991;30(28):6997-7008.
1991: Wiener M C; White S H
Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. II. "Composition-space" refinement method.
Biophysical journal 1991;59(1):174-85.
1991: Wiener M C; White S H
Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. I. Fluid bilayer models and the limits of resolution.
Biophysical journal 1991;59(1):162-73.
1990: White S H; Jacobs R E
Observations concerning topology and locations of helix ends of membrane proteins of known structure.
The Journal of membrane biology 1990;115(2):145-58.
1990: White S H; Jacobs R E
Statistical distribution of hydrophobic residues along the length of protein chains. Implications for protein folding and evolution.
Biophysical journal 1990;57(4):911-21.
1989: Edelman J; White S H
Linear optimization of predictors for secondary structure. Application to transbilayer segments of membrane proteins.
Journal of molecular biology 1989;210(1):195-209.
1989: Jacobs R E; White S H
The nature of the hydrophobic binding of small peptides at the bilayer interface: implications for the insertion of transbilayer helices.
Biochemistry 1989;28(8):3421-37.
1988: White S H; Mirejovsky D; King G I
Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum. An X-ray diffraction study.
Biochemistry 1988;27(10):3725-32.
1987: White S H; Jacobs R E; King G I
Partial specific volumes of lipid and water in mixtures of egg lecithin and water.
Biophysical journal 1987;52(4):663-5.
1987: Jacobs R E; White S H
Lipid bilayer perturbations induced by simple hydrophobic peptides.
Biochemistry 1987;26(19):6127-34.
1986: Jacobs R E; White S H
Mixtures of a series of homologous hydrophobic peptides with lipid bilayers: a simple model system for examining the protein-lipid interface.
Biochemistry 1986;25(9):2605-12.
1986: King G I; White S H
Determining bilayer hydrocarbon thickness from neutron diffraction measurements using strip-function models.
Biophysical journal 1986;49(5):1047-54.
1985: White S H; King G I
Molecular packing and area compressibility of lipid bilayers.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(19):6532-6.
1985: King G I; Jacobs R E; White S H
Hexane dissolved in dioleoyllecithin bilayers has a partial molar volume of approximately zero.
Biochemistry 1985;24(17):4637-45.
1985: Kim S; Jacobs R E; White S H
Preparation of multilamellar vesicles of defined size-distribution by solvent-spherule evaporation.
Biochimica et biophysica acta 1985;812(3):793-801.

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