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Stephen White

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Concepts & Ideas

Procedures

X-Ray Crystallography

Genes & Molecular Sequences

Amino Acid Sequence

Living Beings

Chemicals & Drugs

Phenomena

Anatomy

Ribosomes

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Network (preview)

Co-Publications
Name
16
Rock, Charles
11
Davies, Christopher
8
Price, Allen
8
Zhang, Yong-Mei
6
Bastia, Deepak
6
Bussiere, Dirk
4
Golden, Barbara
4
Miller, Darcie
3
Kreuzer, Kenneth
3
Lee, Richard
3
Babaoglu, Kerim
2
Bahouth, Suleiman
2
Heath, RJ
2
Jackowski, Suzanne
2
Jerga, Agoston

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Publications

TOP 3
Jerga Agoston; Miller Darcie J; White Stephen W; Rock Charles O
Molecular determinants for interfacial binding and conformational change in a soluble diacylglycerol kinase.
Hevener Kirk E; Zhao Wei; Ball David M; Babaoglu Kerim; Qi Jianjun; White Stephen W; Lee Richard E
Validation of molecular docking programs for virtual screening against dihydropteroate synthase.
Zhao Wei; Hevener Kirk E; White Stephen W; Lee Richard E; Boyett James M
A statistical framework to evaluate virtual screening.

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All Publications

2009: Jerga Agoston; Miller Darcie J; White Stephen W; Rock Charles O
Molecular determinants for interfacial binding and conformational change in a soluble diacylglycerol kinase.
The Journal of biological chemistry 2009;284(11):7246-54.
2009: Hevener Kirk E; Zhao Wei; Ball David M; Babaoglu Kerim; Qi Jianjun; White Stephen W; Lee Richard E
Validation of molecular docking programs for virtual screening against dihydropteroate synthase.
Journal of chemical information and modeling 2009;49(2):444-60.
2009: Zhao Wei; Hevener Kirk E; White Stephen W; Lee Richard E; Boyett James M
A statistical framework to evaluate virtual screening.
BMC bioinformatics 2009;10():225.
2008: Miller Darcie J; Jerga Agoston; Rock Charles O; White Stephen W
Analysis of the Staphylococcus aureus DgkB structure reveals a common catalytic mechanism for the soluble diacylglycerol kinases.
Structure (London, England : 1993) 2008;16(7):1036-46.
2007: Kerr Iain D; Sivakolundu Sivashankar; Li Zhenmei; Buchsbaum Jeffrey C; Knox Luke A; Kriwacki Richard; White Stephen W
Crystallographic and NMR analyses of UvsW and UvsW.1 from bacteriophage T4.
The Journal of biological chemistry 2007;282(47):34392-400.
2007: He Xiaoping; van Waardenburg Robert C A M; Babaoglu Kerim; Price Allen C; Nitiss Karin C; Nitiss John L; Bjornsti Mary-Ann; White Stephen W
Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison.
Journal of molecular biology 2007;372(4):1070-81.
2007: Yun Mi-Kyung; Nourse Amanda; White Stephen W; Rock Charles O; Heath Richard J
Crystal structure and allosteric regulation of the cytoplasmic Escherichia coli L-asparaginase I.
Journal of molecular biology 2007;369(3):794-811.
2006: Zeitoun Omeima; Santos Noel M Delos; Gardner Lidia A; White Stephen W; Bahouth Suleiman W
Mutagenesis within helix 6 of the human beta1-adrenergic receptor identifies Lysine324 as a residue involved in imparting the high-affinity binding state of agonists.
Molecular pharmacology 2006;70(3):838-50.
2006: Hong Bum Soo; Yun Mi Kyung; Zhang Yong-Mei; Chohnan Shigeru; Rock Charles O; White Stephen W; Jackowski Suzanne; Park Hee-Won; Leonardi Roberta
Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties.
Structure (London, England : 1993) 2006;14(8):1251-61.
2006: Nitiss Karin C; Malik Mobeen; He Xiaoping; White Stephen W; Nitiss John L
Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):8953-8.
2006: Miller Darcie J; Zhang Yong-Mei; Rock Charles O; White Stephen W
Structure of RhlG, an essential beta-ketoacyl reductase in the rhamnolipid biosynthetic pathway of Pseudomonas aeruginosa.
The Journal of biological chemistry 2006;281(26):18025-32.
2006: Delos Santos Noel M; Gardner Lidia A; White Stephen W; Bahouth Suleiman W
Characterization of the residues in helix 8 of the human beta1-adrenergic receptor that are involved in coupling the receptor to G proteins.
The Journal of biological chemistry 2006;281(18):12896-907.
2006: Kim Pilho; Zhang Yong-Mei; Shenoy Gautham; Nguyen Quynh-Anh; Boshoff Helena I; Manjunatha Ujjini H; Goodwin Michael B; Lonsdale John; Price Allen C; Miller Darcie J; Duncan Ken; White Stephen W; Rock Charles O; Barry Clifton E; Dowd Cynthia S
Structure-activity relationships at the 5-position of thiolactomycin: an intact (5R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherichia coli.
Journal of medicinal chemistry 2006;49(1):159-71.
2005: White Stephen W; Zheng Jie; Zhang Yong-Mei; Rock
The structural biology of type II fatty acid biosynthesis.
Annual review of biochemistry 2005;74():791-831.
2004: Babaoglu Kerim; Qi Jianjun; Lee Richard E; White Stephen W
Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design.
Structure (London, England : 1993) 2004;12(9):1705-17.
2004: Sickmier E Allen; Kreuzer Kenneth N; White Stephen W
The crystal structure of the UvsW helicase from bacteriophage T4.
Structure (London, England : 1993) 2004;12(4):583-92.
2004: Price Allen C; Zhang Yong-Mei; Rock Charles O; White Stephen W
Cofactor-induced conformational rearrangements establish a catalytically competent active site and a proton relay conduit in FabG.
Structure (London, England : 1993) 2004;12(3):417-28.
2003: Price Allen C; Rock Charles O; White Stephen W
The 1.3-Angstrom-resolution crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniae.
Journal of bacteriology 2003;185(14):4136-43.
2002: Heath R J; White S W; Rock C O
Inhibitors of fatty acid synthesis as antimicrobial chemotherapeutics.
Applied microbiology and biotechnology 2002;58(6):695-703.
2002: Jackowski Suzanne; Zhang Yong-Mei; Price Allen C; White Stephen W; Rock Charles O
A missense mutation in the fabB (beta-ketoacyl-acyl carrier protein synthase I) gene confers tiolactomycin resistance to Escherichia coli.
Antimicrobial agents and chemotherapy 2002;46(5):1246-52.
2002: Li Ning; Sickmier E Allen; Zhang Rongguang; Joachimiak Andrzej; White Stephen W
The MotA transcription factor from bacteriophage T4 contains a novel DNA-binding domain: the 'double wing' motif.
Molecular microbiology 2002;43(5):1079-88.
2001: Heath R J; White S W; Rock C O
Lipid biosynthesis as a target for antibacterial agents.
Progress in lipid research 2001;40(6):467-97.
2001: Price A C; Zhang Y M; Rock C O; White S W
Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis.
Biochemistry 2001;40(43):12772-81.
2001: Xu Y; Heath R J; Li Z; Rock C O; White S W
The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
The Journal of biological chemistry 2001;276(20):17373-9.
2001: Li N; Zhang W; White S W; Kriwacki R W
Solution structure of the transcriptional activation domain of the bacteriophage T4 protein, MotA.
Biochemistry 2001;40(14):4293-302.
2001: Zhang Y M; Rao M S; Heath R J; Price A C; Olson A J; Rock C O; White S W
Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III.
The Journal of biological chemistry 2001;276(11):8231-8.
2001: Price A C; Choi K H; Heath R J; Li Z; White S W; Rock C O
Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism.
The Journal of biological chemistry 2001;276(9):6551-9.
2001: Davies C; White S W; Nicholas R A
Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolution.
The Journal of biological chemistry 2001;276(1):616-23.
2000: Davies C; White S W
Electrons and X-rays gang up on the ribosome.
Structure (London, England : 1993) 2000;8(3):R41-5.
2000: Davies C; Heath R J; White S W; Rock C O
The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli.
Structure (London, England : 1993) 2000;8(2):185-95.
1999: White S W; Wilson K S; Appelt K; Tanaka I
The high-resolution structure of DNA-binding protein HU from Bacillus stearothermophilus.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 4):801-9.
1998: Davies C; Gerstner R B; Draper D E; Ramakrishnan V; White S W
The crystal structure of ribosomal protein S4 reveals a two-domain molecule with an extensive RNA-binding surface: one domain shows structural homology to the ETS DNA-binding motif.
The EMBO journal 1998;17(16):4545-58.
1998: Davies C; Bussiere D E; Golden B L; Porter S J; Ramakrishnan V; White S W
Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance.
Journal of molecular biology 1998;279(4):873-88.
1997: Finnin M S; Cicero M P; Davies C; Porter S J; White S W; Kreuzer K N
The activation domain of the MotA transcription factor from bacteriophage T4.
The EMBO journal 1997;16(8):1992-2003.
1996: Manna A C; Pai K S; Bussiere D E; Davies C; White S W; Bastia D
Helicase-contrahelicase interaction and the mechanism of termination of DNA replication.
Cell 1996;87(5):881-91.
1996: Pai K S; Bussiere D E; Wang F; White S W; Bastia D
Structure of the replication terminus-terminator protein complex as probed by affinity cleavage.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10647-52.
1996: Davies C; Ramakrishnan V; White S W
Structural evidence for specific S8-RNA and S8-protein interactions within the 30S ribosomal subunit: ribosomal protein S8 from Bacillus stearothermophilus at 1.9 A resolution.
Structure (London, England : 1993) 1996;4(9):1093-104.
1996: Pai K S; Bussiere D E; Wang F; Hutchison C A; White S W; Bastia D
The structure and function of the replication terminator protein of Bacillus subtilis: identification of the 'winged helix' DNA-binding domain.
The EMBO journal 1996;15(12):3164-73.
1996: Manna A C; Pai K S; Bussiere D E; White S W; Bastia D
The dimer-dimer interaction surface of the replication terminator protein of Bacillus subtilis and termination of DNA replication.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3253-8.
1996: Jaishree T N; Ramakrishnan V; White S W
Solution structure of prokaryotic ribosomal protein S17 by high-resolution NMR spectroscopy.
Biochemistry 1996;35(9):2845-53.
1996: Davies C; White S W; Ramakrishnan V
The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus.
Structure (London, England : 1993) 1996;4(1):55-66.
1995: Ramakrishnan V; Davies C; Gerchman S E; Golden B L; Hoffmann D W; Jaishree T N; Kyila J H; Porter S; White S W
Structures of prokaryotic ribosomal proteins: implications for RNA binding and evolution.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1995;73(11-12):979-86.
1995: Bussiere D E; Bastia D; White S W
Crystal structure of the replication terminator protein from B. subtilis at 2.6 A.
Cell 1995;80(4):651-60.
1994: Finnin M S; Hoffman D W; White S W
The DNA-binding domain of the MotA transcription factor from bacteriophage T4 shows structural similarity to the TATA-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10972-6.
1994: Davies C; Gerchman S E; Kycia J H; McGee K; Ramakrishnan V; White S W
Crystallization and preliminary X-ray diffraction studies of bacterial ribosomal protein L14.
Acta crystallographica. Section D, Biological crystallography 1994;50(Pt 5):790-2.
1994: Hoffman D W; Davies C; Gerchman S E; Kycia J H; Porter S J; White S W; Ramakrishnan V
Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein.
The EMBO journal 1994;13(1):205-12.
1993: Golden B L; Ramakrishnan V; White S W
Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.
The EMBO journal 1993;12(13):4901-8.
1993: Golden B L; Hoffman D W; Ramakrishnan V; White S W
Ribosomal protein S17: characterization of the three-dimensional structure by 1H and 15N NMR.
Biochemistry 1993;32(47):12812-20.
1993: Finnin M S; Hoffman D W; Kreuzer K N; Porter S J; Schmidt R P; White S W
The MotA protein from bacteriophage T4 contains two domains. Preliminary structural analysis by X-ray diffraction and nuclear magnetic resonance.
Journal of molecular biology 1993;232(1):301-4.
1993: Colvin R A; White S W; Garcia-Blanco M A; Hoffman D W
Structural features of an RNA containing the CUGGGA loop of the human immunodeficiency virus type 1 trans-activation response element.
Biochemistry 1993;32(4):1105-12.
1993: Hoffman D W; Colvin R A; Garcia-Blanco M A; White S W
Structural features of the trans-activation response RNA element of equine infectious anemia virus.
Biochemistry 1993;32(4):1096-104.
1992: Mehta P P; Bussiere D E; Hoffman D W; Bastia D; White S W
Crystallization and preliminary structural analysis of the replication terminator protein of Bacillus subtilis.
The Journal of biological chemistry 1992;267(26):18885-9.
1992: Ramakrishnan V; White S W
The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA.
Nature 1992;358(6389):768-71.
1991: Hoffman D W; Query C C; Golden B L; White S W; Keene J D
RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2495-9.
1990: Graziano V; Gerchman S E; Wonacott A J; Sweet R M; Wells J R; White S W; Ramakrishnan V
Crystallization of the globular domain of histone H5.
Journal of molecular biology 1990;212(2):253-7.
1989: White S W; Appelt K; Wilson K S; Tanaka I
A protein structural motif that bends DNA.
Proteins 1989;5(4):281-8.
1988: Leijonmarck M; Appelt K; Badger J; Liljas A; Wilson K S; White S W
Structural comparison of the prokaryotic ribosomal proteins L7/L12 and L30.
Proteins 1988;3(4):243-51.
1986: Wilson K S; Appelt K; Badger J; Tanaka I; White S W
Crystal structure of a prokaryotic ribosomal protein.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7251-5.
1984: Tanaka I; Appelt K; Dijk J; White S W; Wilson K S
3-A resolution structure of a protein with histone-like properties in prokaryotes.
Nature 1984;310(5976):376-81.
1983: Appelt K; White S W; Wilson K S
Proteins of the Bacillus stearothermophilus ribosome. Crystallization of proteins L30 and S5.
The Journal of biological chemistry 1983;258(21):13328-30.
1983: White S W; Appelt K; Dijk J; Wilson K S
Proteins of the Bacillus stearothermophilus ribosome. A 5 A structure analysis of protein S5.
FEBS letters 1983;163(1):73-5.
1983: Appelt K; Dijk J; White S W; Wilson K S
Proteins of the Bacillus stearothermophilus ribosome. Crystallization of protein L6.
FEBS letters 1983;160(1-2):75-7.
1983: Dijk J; White S W; Wilson K S; Appelt K
On the DNA binding protein II from Bacillus stearothermophilus. I. Purification, studies in solution, and crystallization.
The Journal of biological chemistry 1983;258(6):4003-6.
1981: Appelt K; Dijk J; Reinhardt R; Sanhuesa S; White S W; Wilson K S; Yonath A
The crystallization of ribosomal proteins from the 50 S subunit of the Escherichia coli and Bacillus stearothermophilus ribosome.
The Journal of biological chemistry 1981;256(22):11787-90.

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