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Richard Whitley

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David W Kimberlin; Fred D Lakeman; David Lang; Judy Lew; Marian G Michaels; Mark N Prichard; P Sanchez; Sunil K Sood; Michael G Spigarelli; John A Vanchiere; Wen Wan; Richard J Whitley; Nazha Abughali; Mark J Abzug; Edward P Acosta; Krow Ampofo; Negar Ashouri; John S Bradley; Mary T Caserta; Gretchen Cloud; Janet A Englund; Penelope Jester
Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza.
Richard J Whitley
The use of antiviral drugs during the neonatal period.
David W Kimberlin; Huichien Kuo; Fred D Lakeman; Charles T Leach; Choo Hyung Lee; Carol A McCarthy; April Palmer; Misty Parker; Dwight A Powell; Mobeen H Rathore; Joan L Robinson; P Sanchez; Mark Shelton; Gregory Storch; Russell Van Dyke; Wen Wan; LB Weiner; Richard J Whitley; Peter Wright; Nazha Abughali; Amina Ahmed; John S Bradley; Rebecca C Brady; Gretchen A Cloud; Penelope H Dennehy; Lisa M Frenkel; Jill Griffin; Judith Guzman-Cottrill; Richard F Jacobs; Penelope Jester
Oral acyclovir suppression and neurodevelopment after neonatal herpes.

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All Publications

2013: David W Kimberlin; Fred D Lakeman; David Lang; Judy Lew; Marian G Michaels; Mark N Prichard; P Sanchez; Sunil K Sood; Michael G Spigarelli; John A Vanchiere; Wen Wan; Richard J Whitley; Nazha Abughali; Mark J Abzug; Edward P Acosta; Krow Ampofo; Negar Ashouri; John S Bradley; Mary T Caserta; Gretchen Cloud; Janet A Englund; Penelope Jester
Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza.
The Journal of infectious diseases 2013;207(5):709-20.
2012: Richard J Whitley
The use of antiviral drugs during the neonatal period.
Clinics in perinatology 2012;39(1):69-81.
2011: David W Kimberlin; Huichien Kuo; Fred D Lakeman; Charles T Leach; Choo Hyung Lee; Carol A McCarthy; April Palmer; Misty Parker; Dwight A Powell; Mobeen H Rathore; Joan L Robinson; P Sanchez; Mark Shelton; Gregory Storch; Russell Van Dyke; Wen Wan; LB Weiner; Richard J Whitley; Peter Wright; Nazha Abughali; Amina Ahmed; John S Bradley; Rebecca C Brady; Gretchen A Cloud; Penelope H Dennehy; Lisa M Frenkel; Jill Griffin; Judith Guzman-Cottrill; Richard F Jacobs; Penelope Jester
Oral acyclovir suppression and neurodevelopment after neonatal herpes.
The New England journal of medicine 2011;365(14):1284-92.
2011: Maaike Everts; David R Harris; W Blaine Knight; John A Secrist; Richard J Whitley
The Alabama Drug Discovery Alliance: a collaborative partnership to facilitate academic drug discovery.
Pharmaceutical research 2011;28(7):1454-9.
2010: Richard J Whitley; Antonio Volpi; Mike McKendrick; Albert van Wijck; Anne Louise Oaklander
Management of herpes zoster and post-herpetic neuralgia now and in the future.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2010;48 Suppl 1():S20-8.
2010: Richard J Whitley
Of ferrets and humans: influenza pathogenesis.
The Journal of infectious diseases 2010;201(7):976-7.
2009: Sara E Oliver; Gretchen A Cloud; P Sanchez; Gail J Demmler; Wayne Dankner; Mark Shelton; Richard F Jacobs; Wendy Vaudry; Robert F Pass; Seng-Jaw Soong; Richard J Whitley; David W Kimberlin
Neurodevelopmental outcomes following ganciclovir therapy in symptomatic congenital cytomegalovirus infections involving the central nervous system.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2009;46 Suppl 4():S22-6.
2009: Scott H James; David W Kimberlin; Richard J Whitley
Antiviral therapy for herpesvirus central nervous system infections: neonatal herpes simplex virus infection, herpes simplex encephalitis, and congenital cytomegalovirus infection.
Antiviral research 2009;83(3):207-13.
2009: Richard J Whitley
A 70-year-old woman with shingles: review of herpes zoster.
JAMA : the journal of the American Medical Association 2009;302(1):73-80.
2009: James M Markert; Peter G Liechty; Wenquan Wang; Shanna Gaston; Eunice Braz; Matthias Karrasch; L Burt Nabors; Michael Markiewicz; Alfred D Lakeman; Cheryl A Palmer; Jacqueline N Parker; Richard J Whitley; G Yancey Gillespie
Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(1):199-207.
2008: David W Kimberlin; Edward P Acosta; P Sanchez; Sunil Sood; Vish Agrawal; James Homans; Richard F Jacobs; David Lang; Jose R Romero; Jill Griffin; Gretchen A Cloud; Fred D Lakeman; Richard J Whitley
Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease.
The Journal of infectious diseases 2008;197(6):836-45.
2008: Richard J Whitley
Therapy of herpes virus infections in children.
Advances in experimental medicine and biology 2008;609():216-32.
2008: Robert H Dworkin; John W Gnann; Anne Louise Oaklander; Srinivasa N Raja; Kenneth E Schmader; Richard J Whitley
Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia.
The journal of pain : official journal of the American Pain Society 2008;9(1 Suppl 1):S37-44.
2007: Richard J Whitley
The role of oseltamivir in the treatment and prevention of influenza in children.
Expert opinion on drug metabolism & toxicology 2007;3(5):755-67.
2007: Richard J Whitley; John W Gnann
The incidence and severity of herpes simplex encephalitis in Sweden, 1990-2001.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(7):881-2.
2007: Scott D Parker; Scott T Rottinghaus; Allan J Zajac; Ling Yue; Eric Hunter; Richard J Whitley; Jacqueline N Parker
HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice.
Vaccine 2007;25(37-38):6764-73.
2007: Scott T Rottinghaus; Richard J Whitley
Current non-AIDS antiviral chemotherapy.
Expert review of anti-infective therapy 2007;5(2):217-30.
2007: David W Kimberlin; Richard J Whitley
Varicella-zoster vaccine for the prevention of herpes zoster.
The New England journal of medicine 2007;356(13):1338-43.
2007: Robert H Dworkin; Robert W Johnson; Judith Breuer; John W Gnann; Myron J Levin; Misha-Miroslav Backonja; Robert F Betts; Anne A Gershon; Maija L Haanpaa; Michael W McKendrick; Turo J Nurmikko; Anne Louise Oaklander; Michael N Oxman; Deborah Pavan-Langston; Karin Lottrup Petersen; Michael Rowbotham; Kenneth E Schmader; Brett R Stacey; Stephen K Tyring; Albert J M van Wijck; Mark S Wallace; Sawko W Wassilew; Richard J Whitley
Recommendations for the management of herpes zoster.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;44 Suppl 1():S1-26.
2007: M B Guffey; Jacqueline N Parker; W S Luckett; G Yancey Gillespie; Sreelatha Meleth; Richard J Whitley; James M Markert
Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors.
Cancer gene therapy 2007;14(1):45-56.
2006: Richard J Whitley; Arnold S Monto
Seasonal and pandemic influenza preparedness: a global threat.
The Journal of infectious diseases 2006;194 Suppl 2():S65-9.
2006: Richard J Whitley; John G Bartlett; Frederick G Hayden; Andrew T Pavia; Michael Tapper; Arnold S Monto
Seasonal and pandemic influenza: recommendations for preparedness in the United States.
The Journal of infectious diseases 2006;194 Suppl 2():S155-61.
2006: Richard J Whitley; Arnold S Monto
Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents.
The Journal of infectious diseases 2006;194 Suppl 2():S133-8.
2006: James M Markert; Jacqueline N Parker; Donald J Buchsbaum; William E Grizzle; G Yancey Gillespie; Richard J Whitley
Oncolytic HSV-1 for the treatment of brain tumours.
Herpes : the journal of the IHMF 2006;13(3):66-71.
2006: Marwan Shalabi; Richard J Whitley
Recurrent benign lymphocytic meningitis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(9):1194-7.
2006: Richard J Whitley
Herpes simplex encephalitis: adolescents and adults.
Antiviral research 2006;71(2-3):141-8.
2006: Amish C Shah; Kathleen H Price; Jacqueline N Parker; Sharon L Samuel; Sreelatha Meleth; Kevin A Cassady; G Yancey Gillespie; Richard J Whitley; James M Markert
Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors.
Journal of virology 2006;80(15):7308-15.
2006: R A Desmond; Neil A Accortt; Lynya Talley; S A Villano; Seng-Jaw Soong; Richard J Whitley
Enteroviral meningitis: natural history and outcome of pleconaril therapy.
Antimicrobial agents and chemotherapy 2006;50(7):2409-14.
2006: Penelope M Jester; Samuel J Tilden; Yufeng Li; Richard J Whitley; Wayne M Sullender
Regulatory challenges: lessons from recent West Nile virus trials in the United States.
Contemporary clinical trials 2006;27(3):254-9.
2006: Jacqueline N Parker; Luz-Andrea Pfister; Debra C Quenelle; G Yancey Gillespie; James M Markert; Earl R Kern; Richard J Whitley
Genetically engineered herpes simplex viruses that express IL-12 or GM-CSF as vaccine candidates.
Vaccine 2006;24(10):1644-52.
2005: Gary L Davis; David R Nelson; Norah A Terrault; Timothy L Pruett; Thomas D Schiano; Courtney V Fletcher; Christine V Sapan; Laura N Riser; Yufeng Li; Richard J Whitley; John W Gnann
A randomized, open-label study to evaluate the safety and pharmacokinetics of human hepatitis C immune globulin (Civacir) in liver transplant recipients.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(8):941-9.
2005: Elizabeth K Hellums; James M Markert; Jacqueline N Parker; Bin He; Bernard Perbal; Bernard Roizman; Richard J Whitley; Catherine P Langford; Suman Bharara; G Yancey Gillespie
Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model.
Neuro-oncology 2005;7(3):213-24.
2005: Jacqueline N Parker; Sreelatha Meleth; Kenneth B Hughes; G Yancey Gillespie; Richard J Whitley; James M Markert
Enhanced inhibition of syngeneic murine tumors by combinatorial therapy with genetically engineered HSV-1 expressing CCL2 and IL-12.
Cancer gene therapy 2005;12(4):359-68.
2005: Richard J Whitley; Fred D Lakeman
Human herpesvirus 6 infection of the central nervous system: is it just a case of mistaken association?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;40(6):894-5.
2005: Russell D Bradford; Gretchen A Cloud; Alfred D Lakeman; Suresh B Boppana; David W Kimberlin; Richard Jacobs; Gail J Demmler; P Sanchez; William J Britt; Seng-Jaw Soong; Richard J Whitley
Detection of cytomegalovirus (CMV) DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the central nervous system.
The Journal of infectious diseases 2005;191(2):227-33.
2005: Richard J Whitley; David W Kimberlin
Herpes simplex encephalitis: children and adolescents.
Seminars in pediatric infectious diseases 2005;16(1):17-23.
2005: David W Kimberlin; Richard J Whitley
Neonatal herpes: what have we learned.
Seminars in pediatric infectious diseases 2005;16(1):7-16.
2004: Gregory J Mertz; Lilly J Miedzinski; Diane Goade; Andrew T Pavia; Brian Hjelle; Christine O Hansbarger; Howard Levy; Frederick Koster; Kenneth Baum; Adeline Lindemulder; Wenquan Wang; Laura Riser; Humberto Fernandez; Richard J Whitley
Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;39(9):1307-13.
2004: Richard J Whitley
Commentary: Ch'ien LT, Cannon NJ, Charamella LJ, et al. effect of adenine arabinoside on severe herpesvirus hominis infections in man: preliminary report. J Infect Dis 1973; 128:658-63.
The Journal of infectious diseases 2004;190(7):1360-7.
2004: Richard J Whitley
Cytomegalovirus and HIV: inextricably entwined pathogens.
Lancet 2004;363(9427):2101-2.
2004: Richard J Whitley
Congenital cytomegalovirus infection: epidemiology and treatment.
Advances in experimental medicine and biology 2004;549():155-60.
2003: David W Kimberlin; Chin-Yu Lin; P Sanchez; Gail J Demmler; Wayne M Dankner; Mark Shelton; Richard F Jacobs; Wendy Vaudry; Robert F Pass; Jan M Kiell; Seng-Jaw Soong; Richard J Whitley
Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial.
The Journal of pediatrics 2003;143(1):16-25.
2003: Mark J Abzug; Gretchen A Cloud; John Bradley; P Sanchez; José Romero; Dwight Powell; Martha Lepow; Chitra S Mani; Edmund V Capparelli; Sharon Blount; Fred D Lakeman; Richard J Whitley; David W Kimberlin
Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis.
The Pediatric infectious disease journal 2003;22(4):335-41.
2003: Richard J Whitley
Smallpox: a potential agent of bioterrorism.
Antiviral research 2003;57(1-2):7-12.
2002: Sunil J Advani; Ralph R Weichselbaum; Richard J Whitley; Bernard Roizman
Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2002;8(9):551-63.
2002: John W Gnann; Richard J Whitley
Clinical practice. Herpes zoster.
The New England journal of medicine 2002;347(5):340-6.
2002: Richard J Whitley; Bernard Roizman
Herpes simplex viruses: is a vaccine tenable?
The Journal of clinical investigation 2002;110(2):145-51.
2002: Renee A Desmond; Heidi L Weiss; Ramin B Arani; Seng-Jaw Soong; Martin J Wood; Paul A Fiddian; John W Gnann; Richard J Whitley
Clinical applications for change-point analysis of herpes zoster pain.
Journal of pain and symptom management 2002;23(6):510-6.
2002: Richard J Whitley; John W Gnann
Viral encephalitis: familiar infections and emerging pathogens.
Lancet 2002;359(9305):507-13.
2002: Richard J Whitley
Herpes simplex virus infection.
Seminars in pediatric infectious diseases 2002;13(1):6-11.
2002: SM Chung; Sunil J Advani; J D Bradley; Y Kataoka; K Vashistha; S Y Yan; JM Markert; G Yancey Gillespie; Richard J Whitley; Bernard Roizman; Ralph R Weichselbaum
The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma.
Gene therapy 2002;9(1):75-80.
2001: Jon S Abramson; C J Baker; M C Fisher; M A Gerber; H Cody Meissner; Dennis L Murray; G D Overturf; C G Prober; Margaret B Rennels; Thomas N Saari; LB Weiner; Richard J Whitley; Larry K Pickering
Prevention of hepatitis B in adolescents.
Pediatrics 2001;108(6):1392.
2001: David W Kimberlin; Chin-Yu Lin; Richard F Jacobs; D A Powell; Lawrence Corey; WC Gruber; Mobeen H Rathore; J S Bradley; P S Diaz; M Kumar; A M Arvin; K Gutierrez; Mark Shelton; LB Weiner; J W Sleasman; T M de Sierra; S Weller; Seng-Jaw Soong; Jan M Kiell; Fred D Lakeman; Richard J Whitley
Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.
Pediatrics 2001;108(2):230-8.
2001: David W Kimberlin; Chin-Yu Lin; Richard F Jacobs; D A Powell; Lisa M Frenkel; WC Gruber; Mobeen H Rathore; J S Bradley; P S Diaz; M Kumar; A M Arvin; K Gutierrez; Mark Shelton; LB Weiner; J W Sleasman; T M de Sierra; Seng-Jaw Soong; Jan M Kiell; Fred D Lakeman; Richard J Whitley
Natural history of neonatal herpes simplex virus infections in the acyclovir era.
Pediatrics 2001;108(2):223-9.
2001: Richard J Whitley; Bernard Roizman
Herpes simplex virus infections.
Lancet 2001;357(9267):1513-8.
2001: Bernard Roizman; Richard J Whitley
The nine ages of herpes simplex virus.
Herpes : the journal of the IHMF 2001;8(1):23-7.
2001: James M Markert; Jacqueline N Parker; G Yancey Gillespie; Richard J Whitley
Genetically engineered human herpes simplex virus in the treatment of brain tumours.
Herpes : the journal of the IHMF 2001;8(1):17-22.
2001: Richard J Whitley; R L Miller
Immunologic approach to herpes simplex virus.
Viral immunology 2001;14(2):111-8.
2000: James M Markert; G Yancey Gillespie; R R Weichselbaum; Bernard Roizman; Richard J Whitley
Genetically engineered HSV in the treatment of glioma: a review.
Reviews in medical virology 2000;10(1):17-30.
1999: Richard J Whitley; John W Gnann
Herpes zoster: focus on treatment in older adults.
Antiviral research 1999;44(3):145-54.
1999: Harley A Rotbart; G H McCracken; Richard J Whitley; John F Modlin; M Cascino; S Shah; D Blum
Clinical significance of enteroviruses in serious summer febrile illnesses of children.
The Pediatric infectious disease journal 1999;18(10):869-74.
1999: Jon S Abramson; C J Baker; M C Fisher; M A Gerber; H Cody Meissner; Dennis L Murray; G D Overturf; C G Prober; Margaret B Rennels; Thomas N Saari; LB Weiner; Richard J Whitley
Possible association of intussusception with rotavirus vaccination. American Academy of Pediatrics. Committee on Infectious Diseases.
Pediatrics 1999;104(3 Pt 1):575.
1999: J D Bradley; Y Kataoka; S Advani; SM Chung; Ramin B Arani; G Yancey Gillespie; Richard J Whitley; JM Markert; Bernard Roizman; Ralph R Weichselbaum
Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(6):1517-22.
1999: R A Harrison; Seng-Jaw Soong; Heidi L Weiss; John W Gnann; Richard J Whitley
A mixed model for factors predictive of pain in AIDS patients with herpes zoster.
Journal of pain and symptom management 1999;17(6):410-7.
1999: Richard J Whitley; David W Kimberlin
Viral encephalitis.
Pediatrics in review / American Academy of Pediatrics 1999;20(6):192-8.
1999: Sunil J Advani; SM Chung; S Y Yan; G Yancey Gillespie; JM Markert; Richard J Whitley; Bernard Roizman; Ralph R Weichselbaum
Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors.
Cancer research 1999;59(9):2055-8.
1999: Daniel F Martin; James P Dunn; Janet L Davis; J S Duker; Robert E Engstrom; Dorothy N Friedberg; Glenn J Jaffe; Baruch D Kuppermann; M A Polis; Richard J Whitley; Richard A Wolitz; Constance A Benson
Use of the ganciclovir implant for the treatment of cytomegalovirus retinitis in the era of potent antiretroviral therapy: recommendations of the International AIDS Society-USA panel.
American journal of ophthalmology 1999;127(3):329-39.
1999: Richard J Whitley
Approaches to the treatment of varicella-zoster virus infections.
Contributions to microbiology 1999;3():158-72.
1999: Richard J Whitley; John W Gnann
Therapeutic approaches to the management of herpes zoster.
Advances in experimental medicine and biology 1999;458():159-65.
1999: Richard J Whitley; Heidi L Weiss; Seng-Jaw Soong; John W Gnann
Herpes zoster: risk categories for persistent pain.
The Journal of infectious diseases 1999;179(1):9-15.
1998: Mariko Yoshida; Masao Yamada; T Tsukazaki; S Chatterjee; Fred D Lakeman; Shiro Nii; Richard J Whitley
Comparison of antiviral compounds against human herpesvirus 6 and 7.
Antiviral research 1998;40(1-2):73-84.
1998: Richard J Whitley; S Shukla; R J Crooks
The identification of risk factors associated with persistent pain following herpes zoster.
The Journal of infectious diseases 1998;178 Suppl 1():S71-5.
1998: David W Kimberlin; Richard J Whitley
Human herpesvirus-6: neurologic implications of a newly-described viral pathogen.
Journal of neurovirology 1998;4(5):474-85.
1998: Debora F Kimberlin; S Weller; Richard J Whitley; William W Andrews; John C Hauth; Fred D Lakeman; G Miller
Pharmacokinetics of oral valacyclovir and acyclovir in late pregnancy.
American journal of obstetrics and gynecology 1998;179(4):846-51.
1998: RB Domingues; Fred D Lakeman; MS Mayo; Richard J Whitley
Application of competitive PCR to cerebrospinal fluid samples from patients with herpes simplex encephalitis.
Journal of clinical microbiology 1998;36(8):2229-34.
1998: E C Dunkel; D I Scheer; Q Zhu; Richard J Whitley; P A Schaffer; Deborah Pavan-Langston; R J Whitely
Retraction: A rabbit model for human cytomeglovirus--induced chorioretinal disease (J Infect Dis 1993;168:336-44).
The Journal of infectious diseases 1998;177(6):1778.
1998: Richard J Whitley; M A Jacobson; Dorothy N Friedberg; Gary N Holland; Douglas A Jabs; D T Dieterich; W David Hardy; M A Polis; T A Deutsch; J Feinberg; S A Spector; S Walmsley; W Lawrence Drew; William G Powderly; P D Griffiths; Constance A Benson; Harold A Kessler
Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.
Archives of internal medicine 1998;158(9):957-69.
1998: John W Gnann; C S Crumpacker; Jacob P Lalezari; J A Smith; Stephen Tyring; Kenneth Baum; M J Borucki; W P Joseph; Gregory J Mertz; Roy T Steigbigel; Gretchen A Cloud; Seng-Jaw Soong; L C Sherrill; D A DeHertogh; Richard J Whitley
Sorivudine versus acyclovir for treatment of dermatomal herpes zoster in human immunodeficiency virus-infected patients: results from a randomized, controlled clinical trial. Collaborative Antiviral Study Group/AIDS Clinical Trials Group, Herpes Zoster Study Group.
Antimicrobial agents and chemotherapy 1998;42(5):1139-45.
1998: Richard J Whitley; David W Kimberlin; Bernard Roizman
Herpes simplex viruses.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1998;26(3):541-53; quiz 554-5.
1998: Samita Andreansky; Bin He; J van Cott; J McGhee; James M Markert; G Yancey Gillespie; Bernard Roizman; Richard J Whitley
Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins.
Gene therapy 1998;5(1):121-30.
1997: Stephen T Mennemeyer; L P Cyr; Richard J Whitley
Antiviral therapy for neonatal herpes simplex virus: a cost-effectiveness analysis.
The American journal of managed care 1997;3(10):1551-8.
1997: Richard J Whitley; Gretchen A Cloud; WC Gruber; G A Storch; Gail J Demmler; Richard F Jacobs; Wayne M Dankner; S A Spector; S Starr; Robert F Pass; Sergio Stagno; William J Britt; C Alford; Seng-Jaw Soong; X J Zhou; L Sherrill; J M FitzGerald; J P Sommadossi
Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.
The Journal of infectious diseases 1997;175(5):1080-6.
1997: Samita Andreansky; Liliana Soroceanu; E R Flotte; J Chou; James M Markert; G Yancey Gillespie; Bernard Roizman; Richard J Whitley
Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors.
Cancer research 1997;57(8):1502-9.
1997: Harley A Rotbart; A Ahmed; S Hickey; R Dagan; G H McCracken; Richard J Whitley; John F Modlin; M Cascino; JF O'Connell; M A Menegus; D Blum
Diagnosis of enterovirus infection by polymerase chain reaction of multiple specimen types.
The Pediatric infectious disease journal 1997;16(4):409-11.
1997: Richard J Whitley; David W Kimberlin
Treatment of viral infections during pregnancy and the neonatal period.
Clinics in perinatology 1997;24(1):267-83.
1997: Kevin A Cassady; Richard J Whitley
New therapeutic approaches to the alphaherpesvirus infections.
The Journal of antimicrobial chemotherapy 1997;39(2):119-28.
1997: Robert H Dworkin; D Carrington; A Cunningham; Rhonda Kost; Myron J Levin; Michael W McKendrick; Michael N Oxman; B Rentier; Kenneth E Schmader; G Tappeiner; Sawko W Wassilew; Richard J Whitley
Assessment of pain in herpes zoster: lessons learned from antiviral trials.
Antiviral research 1997;33(2):73-85.
1996: David W Kimberlin; F D Lakeman; A M Arvin; C G Prober; L Corey; D A Powell; S K Burchett; R F Jacobs; S E Starr; Richard J Whitley
Application of the polymerase chain reaction to the diagnosis and management of neonatal herpes simplex virus disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.
The Journal of infectious diseases 1996;174(6):1162-7.
1996: Samita Andreansky; Bin He; G Yancey Gillespie; Liliana Soroceanu; James M Markert; J Chou; Bernard Roizman; Richard J Whitley
The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11313-8.
1996: XJ Zhou; W Gruber; G Demmler; R Jacobs; P Reuman; S Adler; M Shelton; Robert F Pass; B Britt; J M Trang; Richard J Whitley; Jean-Pierre Sommadossi
Population pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections. NIAID Collaborative Antiviral Study Group.
Antimicrobial agents and chemotherapy 1996;40(9):2202-5.
1996: Richard J Whitley
The past as prelude to the future: history, status, and future of antiviral drugs.
The Annals of pharmacotherapy 1996;30(9):967-71.
1996: Richard J Whitley; H Weiss; John W Gnann; Stephen Tyring; Gregory J Mertz; Peter G Pappas; Charles Schleupner; F Hayden; J Wolf; Seng-Jaw Soong
Acyclovir with and without prednisone for the treatment of herpes zoster. A randomized, placebo-controlled trial. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.
Annals of internal medicine 1996;125(5):376-83.
1996: Richard J Whitley
Advances in the management of herpesvirus infections. Introduction.
Seminars in dermatology 1996;15(2 Suppl 1):1-3.
1996: Richard J Whitley
Drug discovery for human immunodeficiency virus infection: conquests and hurdles.
The Journal of antimicrobial chemotherapy 1996;37 Suppl B():151-9.
1996: Mariko Yoshida; Masao Yamada; S Chatterjee; F Lakeman; S Nii; Richard J Whitley
A method for detection of HHV-6 antigens and its use for evaluating antiviral drugs.
Journal of virological methods 1996;58(1-2):137-43.
1996: David W Kimberlin; Richard J Whitley
Antiviral resistance: mechanisms, clinical significance, and future implications.
The Journal of antimicrobial chemotherapy 1996;37(3):403-21.
1996: Richard J Whitley; John W Gnann; Heidi L Weiss; Seng-Jaw Soong
Unique clinical trial design: combination acyclovir plus prednisone therapy of localized zoster in the normal host.
Antiviral research 1996;29(1):67-8.
1995: Richard J Whitley
Sorivudine: a promising drug for the treatment of varicella-zoster virus infection.
Neurology 1995;45(12 Suppl 8):S73-5.
1995: J A McCullers; F D Lakeman; Richard J Whitley
Human herpesvirus 6 is associated with focal encephalitis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;21(3):571-6.
1995: F D Lakeman; Richard J Whitley
Diagnosis of herpes simplex encephalitis: application of polymerase chain reaction to cerebrospinal fluid from brain-biopsied patients and correlation with disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.
The Journal of infectious diseases 1995;171(4):857-63.
1995: David W Kimberlin; Robert B Couch; G J Galasso; D D Richman; Richard J Whitley
Research initiatives in studies of antiviral resistance and consensus points and recommendations.
Antiviral research 1995;26(4):439-52.
1995: David W Kimberlin; C S Crumpacker; S E Straus; K K Biron; W Lawrence Drew; F G Hayden; M McKinlay; D D Richman; Richard J Whitley
Antiviral resistance in clinical practice.
Antiviral research 1995;26(4):423-38.
1995: David W Kimberlin; Earl R Kern; R W Sidwell; T W North; Richard J Whitley
Models of antiviral resistance.
Antiviral research 1995;26(4):415-22.
1995: David W Kimberlin; S A Spector; E L Hill; K K Biron; A J Hay; D L Mayers; Richard J Whitley
Assays for antiviral drug resistance.
Antiviral research 1995;26(4):403-13.
1995: David W Kimberlin; D M Coen; K K Biron; J I Cohen; R A Lamb; M McKinlay; E A Emini; Richard J Whitley
Molecular mechanisms of antiviral resistance.
Antiviral research 1995;26(4):369-401.
1995: David W Kimberlin; Richard J Whitley
Antiviral resistance--an emerging problem.
Antiviral research 1995;26(4):365-8.
1995: R Chambers; G Yancey Gillespie; Liliana Soroceanu; Samita Andreansky; S Chatterjee; J Chou; Bernard Roizman; Richard J Whitley
Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1411-5.
1995: Richard J Whitley; F Lakeman
Herpes simplex virus infections of the central nervous system: therapeutic and diagnostic considerations.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;20(2):414-20.
1994: N N Gangopadhyay; Richard J Whitley; S Chatterjee
A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents.
Journal of virological methods 1994;48(2-3):273-9.
1994: Richard J Whitley
Neonatal herpes simplex virus infections: is there a role for immunoglobulin in disease prevention and therapy?
The Pediatric infectious disease journal 1994;13(5):432-8; discussion 438-9.
1994: Richard J Whitley
Herpes simplex virus infections of women and their offspring: implications for a developed society.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2441-7.
1993: Richard J Whitley
Prospects for vaccination against herpes simplex virus.
Pediatric annals 1993;22(12):726, 729-32.
1993: Michael S Saag; Emilio A Emini; O L Laskin; J Douglas; W I Lapidus; William A Schleif; Richard J Whitley; C Hildebrand; V W Byrnes; John C Kappes
A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group.
The New England journal of medicine 1993;329(15):1065-72.
1993: Richard J Whitley; Earl R Kern; S Chatterjee; J Chou; Bernard Roizman
Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models.
The Journal of clinical investigation 1993;91(6):2837-43.
1993: Richard J Whitley
Neonatal herpes simplex virus infections.
Journal of medical virology 1993;Suppl 1():13-21.
1992: Richard J Whitley; John W Gnann
Acyclovir: a decade later.
The New England journal of medicine 1992;327(11):782-9.
1992: S Chatterjee; P Burns; Richard J Whitley; Earl R Kern
Effect of (S)-1-[(3-hydroxy-2-phosphonyl methoxy) propyl] cytosine on the replication and morphogenesis of herpes simplex virus type 1.
Antiviral research 1992;19(3):181-92.
1992: Richard J Whitley
Therapeutic approaches to varicella-zoster virus infections.
The Journal of infectious diseases 1992;166 Suppl 1():S51-7.
1992: Richard J Whitley; John W Gnann; D Hinthorn; C Liu; Richard B Pollard; F Hayden; Gregory J Mertz; M Oxman; Seng-Jaw Soong
Disseminated herpes zoster in the immunocompromised host: a comparative trial of acyclovir and vidarabine. The NIAID Collaborative Antiviral Study Group.
The Journal of infectious diseases 1992;165(3):450-5.
1991: Richard J Whitley
Herpes simplex virus infections of the central nervous system. Encephalitis and neonatal herpes.
Drugs 1991;42(3):406-27.
1991: Michael S Saag; M J Crain; W D Decker; S Campbell-Hill; S Robinson; W E Brown; M Leuther; Richard J Whitley; Beatrice H Hahn; George M Shaw
High-level viremia in adults and children infected with human immunodeficiency virus: relation to disease stage and CD4+ lymphocyte levels.
The Journal of infectious diseases 1991;164(1):72-80.
1991: J W Gnann; Richard J Whitley
Natural history and treatment of varicella-zoster in high-risk populations.
The Journal of hospital infection 1991;18 Suppl A():317-29.
1990: J Chou; E R Kern; Richard J Whitley; Bernard Roizman
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture.
Science (New York, N.Y.) 1990;250(4985):1262-6.
1990: Richard J Whitley
Viral encephalitis.
The New England journal of medicine 1990;323(4):242-50.
1990: S Chatterjee; S Nishimuro; Richard J Whitley
Expression of HSV-1 glycoproteins in tunicamycin-treated monkey kidney cells.
Biochemical and biophysical research communications 1990;167(3):1139-45.
1990: Richard J Whitley; J Connell; M A Markiewicz; Jean-Pierre Sommadossi
Novel pharmacological strategies in the treatment of life-threatening cytomegalovirus infections. Clinical experience with continuous infusion 9-(1,3-dihydroxy-2-propoxymethyl) guanine.
Annals of the New York Academy of Sciences 1990;616():452-60.
1990: Richard J Whitley; M Middlebrooks; John W Gnann
Acyclovir: the past ten years.
Advances in experimental medicine and biology 1990;278():243-53.
1990: A Canessa; S Chatterjee; Richard J Whitley; E F Prasthofer; C E Grossi; A B Tilden
Individual NK cell clones lyse both tumor cell targets and herpes simplex virus-infected fibroblasts in the absence of interferon.
Viral immunology 1990;3(3):217-24.
1989: Richard J Whitley
Varicella-zoster virus infections: chronic disease in the immunocompromised host: evidence for persistent excretion of virus.
The Pediatric infectious disease journal 1989;8(9):584-5.
1989: S Chatterjee; J Koga; Richard J Whitley
A role for herpes simplex virus type 1 glycoprotein E in induction of cell fusion.
The Journal of general virology 1989;70 ( Pt 8)():2157-62.
1989: Richard J Whitley; C G Cobbs; C A Alford; Seng-Jaw Soong; M S Hirsch; J D Connor; L Corey; Daniel F Hanley; M Levin; D A Powell
Diseases that mimic herpes simplex encephalitis. Diagnosis, presentation, and outcome. NIAD Collaborative Antiviral Study Group.
JAMA : the journal of the American Medical Association 1989;262(2):234-9.
1989: S Baldwin; Richard J Whitley
Intrauterine herpes simplex virus infection.
Teratology 1989;39(1):1-10.
1989: S Chatterjee; Richard J Whitley
Effect of recombinant hybrid human interferon on replication and morphogenesis of HSV-1 in monkey cells.
Virus research 1989;12(1):33-41.
1988: J Kahlon; Richard J Whitley
Antibody response of the newborn after herpes simplex virus infection.
The Journal of infectious diseases 1988;158(5):925-33.
1988: Richard J Whitley
Herpes simplex virus infections of the central nervous system. A review.
The American journal of medicine 1988;85(2A):61-7.
1988: L M Grimaldi; Raymond P Roos; R Manservigi; Patricia G Spear; F D Lakeman; Richard J Whitley
An isoelectric focusing study in herpes simplex virus encephalitis.
Annals of neurology 1988;24(2):227-32.
1988: Richard J Whitley; L Corey; A Arvin; F D Lakeman; C V Sumaya; P F Wright; L M Dunkle; R W Steele; Seng-Jaw Soong; A J Nahmias
Changing presentation of herpes simplex virus infection in neonates.
The Journal of infectious diseases 1988;158(1):109-16.
1988: S Baldwin; Sergio Stagno; G T Odrezin; D R Kelly; Richard J Whitley
Isolated Cryptococcus neoformans osteomyelitis in an immunocompetent child.
The Pediatric infectious disease journal 1988;7(4):289-92.
1988: Richard J Whitley
Antiviral treatment of a serious herpes simplex infection: encephalitis.
Journal of the American Academy of Dermatology 1988;18(1 Pt 2):209-11.
1987: R Cauda; E F Prasthofer; C E Grossi; Richard J Whitley; R F Pass
Congenital cytomegalovirus: immunological alterations.
Journal of medical virology 1987;23(1):41-9.
1987: J Kahlon; S Chatterjee; F D Lakeman; F Lee; A J Nahmias; Richard J Whitley
Detection of antibodies to herpes simplex virus in the cerebrospinal fluid of patients with herpes simplex encephalitis.
The Journal of infectious diseases 1987;155(1):38-44.
1987: R Cauda; E F Prasthofer; A B Tilden; Richard J Whitley; C E Grossi
T-cell imbalances and NK activity in varicella-zoster virus infections.
Viral immunology 1987;1(2):145-52.
1986: J Kahlon; F D Lakeman; M Ackermann; Richard J Whitley
Human antibody response to herpes simplex virus-specific polypeptides after primary and recurrent infection.
Journal of clinical microbiology 1986;23(4):725-30.
1985: Richard J Whitley; Seng-Jaw Soong; C A Alford; M S Hirsch; R Schooley; M N Oxman; J D Connor; R Betts; R Dolin; R C Reichman
Design of therapeutic studies in herpes simplex encephalitis.
Lancet 1985;1(8423):284-5.
1982: Richard J Whitley; Seng-Jaw Soong; R Dolin; R Betts; C Linnemann; C A Alford
Early vidarabine therapy to control the complications of herpes zoster in immunosuppressed patients.
The New England journal of medicine 1982;307(16):971-5.