Jeffrey Whitsett

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Korfhagen Thomas R; Le Cras Timothy D; Davidson Cynthia R; Schmidt Stephanie M; Ikegami Machiko; Whitsett Jeffrey A; Hardie William D
Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis.
Ikegami Machiko; Weaver Timothy E; Grant Shawn N; Whitsett Jeffrey A
Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation.
Kramer Elizabeth L; Mushaben Elizabeth M; Pastura Patricia A; Acciani Thomas H; Deutsch Gail H; Khurana Hershey Gurjit K; Korfhagen Thomas R; Hardie William D; Whitsett Jeffrey A; Le Cras Timothy D
Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice.

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All Publications

2009: Korfhagen Thomas R; Le Cras Timothy D; Davidson Cynthia R; Schmidt Stephanie M; Ikegami Machiko; Whitsett Jeffrey A; Hardie William D
Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2009;41(5):562-72.
2009: Ikegami Machiko; Weaver Timothy E; Grant Shawn N; Whitsett Jeffrey A
Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation.
American journal of respiratory cell and molecular biology 2009;41(4):433-9.
2009: Kramer Elizabeth L; Mushaben Elizabeth M; Pastura Patricia A; Acciani Thomas H; Deutsch Gail H; Khurana Hershey Gurjit K; Korfhagen Thomas R; Hardie William D; Whitsett Jeffrey A; Le Cras Timothy D
Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice.
American journal of respiratory cell and molecular biology 2009;41(4):415-25.
2009: Lin Wei; Metzakopian Emmanouil; Mavromatakis Yannis E; Gao Nan; Balaskas Nikolaos; Sasaki Hiroshi; Briscoe James; Whitsett Jeffrey A; Goulding Martyn; Kaestner Klaus H; Ang Siew-Lan
Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.
Developmental biology 2009;333(2):386-96.
2009: Xu Yan; Saegusa Chika; Schehr Angelica; Grant Shawn; Whitsett Jeffrey A; Ikegami Machiko
C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia.
American journal of physiology. Lung cellular and molecular physiology 2009;297(2):L286-98.
2009: Spence Jason R; Lange Alex W; Lin Suh-Chin J; Kaestner Klaus H; Lowy Andrew M; Kim Injune; Whitsett Jeffrey A; Wells James M
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells.
Developmental cell 2009;17(1):62-74.
2009: Ikegami Machiko; Grant Shawn; Korfhagen Thomas; Scheule Ronald K; Whitsett Jeffrey A
Surfactant protein-D regulates the postnatal maturation of pulmonary surfactant lipid pool sizes.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;106(5):1545-52.
2009: Besnard Valérie; Wert Susan E; Stahlman Mildred T; Postle Anthony D; Xu Yan; Ikegami Machiko; Whitsett Jeffrey A
Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts.
The Journal of biological chemistry 2009;284(6):4018-30.
2009: Lange Alexander W; Keiser Angela R; Wells James M; Zorn Aaron M; Whitsett Jeffrey A
Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 signaling to initiate progenitor cell behavior in the respiratory epithelium.
PloS one 2009;4(5):e5711.
2008: Kalin Tanya V; Wang I-Ching; Meliton Lucille; Zhang Yufang; Wert Susan E; Ren Xiaomeng; Snyder Jonathan; Bell Sheila M; Graf Lloyd; Whitsett Jeffrey A; Kalinichenko Vladimir V
Forkhead Box m1 transcription factor is required for perinatal lung function.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(49):19330-5.
2008: Suzuki Takuji; Sakagami Takuro; Rubin Bruce K; Nogee Lawrence M; Wood Robert E; Zimmerman Sarah L; Smolarek Teresa; Dishop Megan K; Wert Susan E; Whitsett Jeffrey A; Grabowski Gregory; Carey Brenna C; Stevens Carrie; van der Loo Johannes C M; Trapnell Bruce C
Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.
The Journal of experimental medicine 2008;205(12):2703-10.
2008: Kalin Tanya V; Meliton Lucille; Meliton Angelo Y; Zhu Xiangdong; Whitsett Jeffrey A; Kalinichenko Vladimir V
Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene.
American journal of respiratory cell and molecular biology 2008;39(4):390-9.
2008: Chaiworapongsa Tinnakorn; Hong Joon-Seok; Hull William M; Romero Roberto; Whitsett Jeffrey A
Amniotic fluid concentration of surfactant proteins in intra-amniotic infection.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2008;21(9):663-70.
2008: Chaiworapongsa Tinnakorn; Hong Joon-Seok; Hull William M; Kim Chong Jai; Gomez Ricardo; Mazor Moshe; Romero Roberto; Whitsett Jeffrey A
The concentration of surfactant protein-A in amniotic fluid decreases in spontaneous human parturition at term.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2008;21(9):652-9.
2008: Cardoso Wellington V; Whitsett Jeffrey A
Resident cellular components of the lung: developmental aspects.
Proceedings of the American Thoracic Society 2008;5(7):767-71.
2008: Wan Huajing; Luo Fengming; Wert Susan E; Zhang Liqian; Xu Yan; Ikegami Machiko; Maeda Yutaka; Bell Sheila M; Whitsett Jeffrey A
Kruppel-like factor 5 is required for perinatal lung morphogenesis and function.
Development (Cambridge, England) 2008;135(15):2563-72.
2008: Glasser Stephan W; Senft Albert P; Whitsett Jeffrey A; Maxfield Melissa D; Ross Gary F; Richardson Theresa R; Prows Daniel R; Xu Yan; Korfhagen Thomas R
Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):621-8.
2008: Zhang Yuzhen; Goss Ashley M; Cohen Ethan David; Kadzik Rachel; Lepore John J; Muthukumaraswamy Karthika; Yang Jifu; DeMayo Francesco J; Whitsett Jeffrey A; Parmacek Michael S; Morrisey Edward E
A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.
Nature genetics 2008;40(7):862-70.
2008: Kida Hiroshi; Mucenski Michael L; Thitoff Angela R; Le Cras Timothy D; Park Kwon-Sik; Ikegami Machiko; Müller Werner; Whitsett Jeffrey A
GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium.
The American journal of pathology 2008;172(6):1542-54.
2008: Hardie William D; Davidson Cynthia; Ikegami Machiko; Leikauf George D; Le Cras Timothy D; Prestridge Adrienne; Whitsett Jeffrey A; Korfhagen Thomas R
EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2008;294(6):L1217-25.
2008: Maeda Yutaka; Suzuki Takuji; Pan Xiufang; Chen Gang; Pan Songqin; Bartman Thomas; Whitsett Jeffrey A
CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis.
The Journal of biological chemistry 2008;283(23):16084-92.
2008: Ikegami Machiko; Falcone Angelica; Whitsett Jeffrey A
STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;104(6):1753-60.
2008: Quinton Lee J; Jones Matthew R; Robson Bryanne E; Simms Benjamin T; Whitsett Jeffrey A; Mizgerd Joseph P
Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia.
American journal of respiratory cell and molecular biology 2008;38(6):699-706.
2008: Brandt Eric B; Mingler Melissa K; Stevenson Michelle D; Wang Ning; Khurana Hershey Gurjit K; Whitsett Jeffrey A; Rothenberg Marc E
Surfactant protein D alters allergic lung responses in mice and human subjects.
The Journal of allergy and clinical immunology 2008;121(5):1140-1147.e2.
2008: Matsuzaki Yohei; Besnard Valérie; Clark Jean C; Xu Yan; Wert Susan E; Ikegami Machiko; Whitsett Jeffrey A
STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells.
American journal of respiratory cell and molecular biology 2008;38(5):551-8.
2008: Whitsett Jeffrey A
Hereditary disorders of surfactant homeostasis cause acute and chronic lung disease in infancy.
Thorax 2008;63(4):295-6.
2008: Sun Jianping; Chen Hui; Chen Cheng; Whitsett Jeffrey A; Mishina Yuji; Bringas Pablo; Ma Jeffrey C; Warburton David; Shi Wei
Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation.
The American journal of pathology 2008;172(3):571-82.
2008: Bell Sheila M; Schreiner Claire M; Wert Susan E; Mucenski Michael L; Scott William J; Whitsett Jeffrey A
R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis.
Development (Cambridge, England) 2008;135(6):1049-58.
2008: Davé Vrushank; Wert Susan E; Tanner Tiffany; Thitoff Angela R; Loudy Dave E; Whitsett Jeffrey A
Conditional deletion of Pten causes bronchiolar hyperplasia.
American journal of respiratory cell and molecular biology 2008;38(3):337-45.
2008: Wedig Kathy E; Whitsett Jeffrey A
Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition.
The Journal of pediatrics 2008;152(1):140, 140.e1.
2008: Tran Phuoc T; Fan Alice C; Bendapudi Pavan K; Koh Shan; Komatsubara Kim; Chen Joy; Horng George; Bellovin David I; Giuriato Sylvie; Wang Craig S; Whitsett Jeffrey A; Felsher Dean W
Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas.
PloS one 2008;3(5):e2125.
2007: Besnard Valérie; Xu Yan; Whitsett Jeffrey A
Sterol response element binding protein and thyroid transcription factor-1 (Nkx2.1) regulate Abca3 gene expression.
American journal of physiology. Lung cellular and molecular physiology 2007;293(6):L1395-405.
2007: Ikegami Machiko; Scoville Elizabeth A; Grant Shawn; Korfhagen Thomas; Brondyk William; Scheule Ronald K; Whitsett Jeffrey A
Surfactant protein-D and surfactant inhibit endotoxin-induced pulmonary inflammation.
Chest 2007;132(5):1447-54.
2007: Tichelaar Jay W; Wesselkamper Scott C; Chowdhury Supurna; Yin Hulian; Berclaz Pierre-Yves; Sartor Maureen A; Leikauf George D; Whitsett Jeffrey A
Duration-dependent cytoprotective versus inflammatory effects of lung epithelial fibroblast growth factor-7 expression.
Experimental lung research 2007;33(8-9):385-417.
2007: Yanagi Shigehisa; Kishimoto Hiroyuki; Kawahara Kohichi; Sasaki Takehiko; Sasaki Masato; Nishio Miki; Yajima Nobuyuki; Hamada Koichi; Horie Yasuo; Kubo Hiroshi; Whitsett Jeffrey A; Mak Tak Wah; Nakano Toru; Nakazato Masamitsu; Suzuki Akira
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.
The Journal of clinical investigation 2007;117(10):2929-40.
2007: Hardie William D; Korfhagen Thomas R; Sartor Maureen A; Prestridge Adrienne; Medvedovic Mario; Le Cras Timothy D; Ikegami Machiko; Wesselkamper Scott C; Davidson Cynthia; Dietsch Maggie; Nichols William; Whitsett Jeffrey A; Leikauf George D
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2007;37(3):309-21.
2007: Ferri Anna L M; Lin Wei; Mavromatakis Yannis E; Wang Julie C; Sasaki Hiroshi; Whitsett Jeffrey A; Ang Siew-Lan
Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.
Development (Cambridge, England) 2007;134(15):2761-9.
2007: Yamamoto Hiroaki; Yun Eun Jun; Gerber Hans-Peter; Ferrara Napoleone; Whitsett Jeffrey A; Vu Thiennu H
Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis.
Developmental biology 2007;308(1):44-53.
2007: Park Kwon-Sik; Korfhagen Thomas R; Bruno Michael D; Kitzmiller Joseph A; Wan Huajing; Wert Susan E; Khurana Hershey Gurjit K; Chen Gang; Whitsett Jeffrey A
SPDEF regulates goblet cell hyperplasia in the airway epithelium.
The Journal of clinical investigation 2007;117(4):978-88.
2007: Saugstad Ola D; Hansen Thor Willy Ruud; Rønnestad Arild; Nakstad Britt; Tølløfsrud Per Arne; Reinholt Finn; Hamvas Aaron; Coles F Sessions; Dean Michael; Wert Susan E; Whitsett Jeffrey A; Nogee Lawrence M
Novel mutations in the gene encoding ATP binding cassette protein member A3 (ABCA3) resulting in fatal neonatal lung disease.
Acta paediatrica (Oslo, Norway : 1992) 2007;96(2):185-90.
2007: Senft Albert P; Korfhagen Thomas R; Whitsett Jeffrey A; LeVine Ann Marie
Surfactant protein D regulates the cell surface expression of alveolar macrophage beta(2)-integrins.
American journal of physiology. Lung cellular and molecular physiology 2007;292(2):L469-75.
2007: Maeda Yutaka; Davé Vrushank; Whitsett Jeffrey A
Transcriptional control of lung morphogenesis.
Physiological reviews 2007;87(1):219-44.
2007: Stahlman Mildred T; Besnard Valérie; Wert Susan E; Weaver Timothy E; Dingle Sharon; Xu Yan; von Zychlin Kara; Olson Sandra J; Whitsett Jeffrey A
Expression of ABCA3 in developing lung and other tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(1):71-83.
2007: Berclaz Pierre-Yves; Carey Brenna; Fillipi Marie-Dominique; Wernke-Dollries Kara; Geraci Nick; Cush Stephanie; Richardson Terry; Kitzmiller Joe; O'connor Michael; Hermoyian Christina; Korfhagen Thomas; Whitsett Jeffrey A; Trapnell Bruce C
GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS.
American journal of respiratory cell and molecular biology 2007;36(1):114-21.
2007: Bry Kristina; Whitsett Jeffrey A; Lappalainen Urpo
IL-1beta disrupts postnatal lung morphogenesis in the mouse.
American journal of respiratory cell and molecular biology 2007;36(1):32-42.
2007: Xu Yan; Ikegami Machiko; Wang Yanhua; Matsuzaki Yohei; Whitsett Jeffrey A
Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells.
BMC genomics 2007;8():455.
2006: Prestridge Adrienne; Wooldridge Jamie; Deutsch Gail; Young Lisa R; Wert Susan E; Whitsett Jeffrey A; Nogee Lawrence
Persistent tachypnea and hypoxia in a 3-month-old term infant.
The Journal of pediatrics 2006;149(5):702-706.
2006: Whitsett Jeffrey A; Matsuzaki Yohei
Transcriptional regulation of perinatal lung maturation.
Pediatric clinics of North America 2006;53(5):873-87, viii.
2006: Davé Vrushank; Childs Tawanna; Xu Yan; Ikegami Machiko; Besnard Valérie; Maeda Yutaka; Wert Susan E; Neilson Joel R; Crabtree Gerald R; Whitsett Jeffrey A
Calcineurin/Nfat signaling is required for perinatal lung maturation and function.
The Journal of clinical investigation 2006;116(10):2597-609.
2006: Akei Hiroko; Whitsett Jeffrey A; Buroker Michelle; Ninomiya Takafumi; Tatsumi Haruyuki; Weaver Timothy E; Ikegami Machiko
Surface tension influences cell shape and phagocytosis in alveolar macrophages.
American journal of physiology. Lung cellular and molecular physiology 2006;291(4):L572-9.
2006: Kingma Paul S; Zhang Liqian; Ikegami Machiko; Hartshorn Kevan; McCormack Francis X; Whitsett Jeffrey A
Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D.
The Journal of biological chemistry 2006;281(34):24496-505.
2006: Zhang Liqian; Ikegami Machiko; Korfhagen Thomas R; McCormack Francis X; Yoshida Mitsuhiro; Senior Robert M; Shipley J Michael; Shapiro Steven D; Whitsett Jeffrey A
Neither SP-A nor NH2-terminal domains of SP-A can substitute for SP-D in regulation of alveolar homeostasis.
American journal of physiology. Lung cellular and molecular physiology 2006;291(2):L181-90.
2006: Matsuzaki Yohei; Xu Yan; Ikegami Machiko; Besnard Valérie; Park Kwon-Sik; Hull William M; Wert Susan E; Whitsett Jeffrey A
Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):527-37.
2006: Garmany Tami H; Moxley Michael A; White Frances V; Dean Michael; Hull William M; Whitsett Jeffrey A; Nogee Lawrence M; Hamvas Aaron
Surfactant composition and function in patients with ABCA3 mutations.
Pediatric research 2006;59(6):801-5.
2006: Kingma Paul S; Whitsett Jeffrey A
In defense of the lung: surfactant protein A and surfactant protein D.
Current opinion in pharmacology 2006;6(3):277-83.
2006: Park Kwon-Sik; Wells James M; Zorn Aaron M; Wert Susan E; Whitsett Jeffrey A
Sox17 influences the differentiation of respiratory epithelial cells.
Developmental biology 2006;294(1):192-202.
2006: Ikegami Machiko; Carter Karen; Bishop Kimberly; Yadav Annuradha; Masterjohn Elizabeth; Brondyk William; Scheule Ronald K; Whitsett Jeffrey A
Intratracheal recombinant surfactant protein d prevents endotoxin shock in the newborn preterm lamb.
American journal of respiratory and critical care medicine 2006;173(12):1342-7.
2006: Whitsett Jeffrey A; Perl Anne-Karina T
Conditional control of gene expression in the respiratory epithelium: A cautionary note.
American journal of respiratory cell and molecular biology 2006;34(5):519-20.
2006: Maeda Yutaka; Hunter Thomas C; Loudy David E; Davé Vrushank; Schreiber Valérie; Whitsett Jeffrey A
PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B.
The Journal of biological chemistry 2006;281(14):9600-6.
2006: Xu Yan; Liu Cong; Clark Jean C; Whitsett Jeffrey A
Functional genomic responses to cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR(delta508) in the lung.
The Journal of biological chemistry 2006;281(16):11279-91.
2006: Köhl Jörg; Baelder Ralf; Lewkowich Ian P; Pandey Manoj K; Hawlisch Heiko; Wang Lihua; Best Jennifer; Herman Nancy S; Sproles Alyssa A; Zwirner Jörg; Whitsett Jeffrey A; Gerard Craig; Sfyroera Georgia; Lambris John D; Wills-Karp Marsha
A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.
The Journal of clinical investigation 2006;116(3):783-96.
2006: Martis Prithy C; Whitsett Jeffrey A; Xu Yan; Perl Anne-Karina T; Wan Huajing; Ikegami Machiko
C/EBPalpha is required for lung maturation at birth.
Development (Cambridge, England) 2006;133(6):1155-64.
2006: Park Kwon-Sik; Wells James M; Zorn Aaron M; Wert Susan E; Laubach Victor E; Fernandez Lucas G; Whitsett Jeffrey A
Transdifferentiation of ciliated cells during repair of the respiratory epithelium.
American journal of respiratory cell and molecular biology 2006;34(2):151-7.
2006: Yoshida Mitsuhiro; Whitsett Jeffrey A
Alveolar macrophages and emphysema in surfactant protein-D-deficient mice.
Respirology (Carlton, Vic.) 2006;11 Suppl():S37-40.
2006: Whitsett Jeffrey A
Disorders of lung morphogenesis.
Paediatric respiratory reviews 2006;7 Suppl 1():S248.
2006: Whitsett Jeffrey A
Genetic disorders of surfactant homeostasis.
Paediatric respiratory reviews 2006;7 Suppl 1():S240-2.
2005: Floyd Heather S; Farnsworth Charles L; Kock Nancy D; Mizesko Melissa C; Little Joy L; Dance Stephanie T; Everitt Jeff; Tichelaar Jay; Whitsett Jeffrey A; Miller Mark Steven
Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model.
Carcinogenesis 2005;26(12):2196-206.
2005: Mucenski Michael L; Nation Jennifer M; Thitoff Angela R; Besnard Valérie; Xu Yan; Wert Susan E; Harada Naomoto; Taketo Makoto M; Stahlman Mildred T; Whitsett Jeffrey A
Beta-catenin regulates differentiation of respiratory epithelial cells in vivo.
American journal of physiology. Lung cellular and molecular physiology 2005;289(6):L971-9.
2005: Ikegami Machiko; Whitsett Jeffrey A; Martis Prithy C; Weaver Timothy E
Reversibility of lung inflammation caused by SP-B deficiency.
American journal of physiology. Lung cellular and molecular physiology 2005;289(6):L962-70.
2005: Lawson William E; Polosukhin Vasiliy V; Stathopoulos Georgios T; Zoia Ornella; Han Wei; Lane Kirk B; Li Bo; Donnelly Edwin F; Holburn George E; Lewis Kenneth G; Collins Robert D; Hull William M; Glasser Stephan W; Whitsett Jeffrey A; Blackwell Timothy S
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin.
The American journal of pathology 2005;167(5):1267-77.
2005: Besnard V; Wert S E; Kaestner K H; Whitsett J A
Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1.
American journal of physiology. Lung cellular and molecular physiology 2005;289(5):L750-9.
2005: Perl Anne-Karina T; Wert Susan E; Loudy David E; Shan Zhengyuan; Blair Paula A; Whitsett Jeffrey A
Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli.
American journal of respiratory cell and molecular biology 2005;33(5):455-62.
2005: Yang Ching-Hui; Szeliga Jacek; Jordan Jeremy; Faske Shawn; Sever-Chroneos Zvjezdana; Dorsett Bre; Christian Robert E; Settlage Robert E; Shabanowitz Jeffrey; Hunt Donald F; Whitsett Jeffrey A; Chroneos Zissis C
Identification of the surfactant protein A receptor 210 as the unconventional myosin 18A.
The Journal of biological chemistry 2005;280(41):34447-57.
2005: Bullard Janine E; Wert Susan E; Whitsett Jeffrey A; Dean Michael; Nogee Lawrence M
ABCA3 mutations associated with pediatric interstitial lung disease.
American journal of respiratory and critical care medicine 2005;172(8):1026-31.
2005: Shu Weiguo; Guttentag Susan; Wang Zhishan; Andl Thomas; Ballard Philip; Lu Min Min; Piccolo Stefano; Birchmeier Walter; Whitsett Jeffrey A; Millar Sarah E; Morrisey Edward E
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung.
Developmental biology 2005;283(1):226-39.
2005: Ikegami Machiko; Le Cras Timothy D; Hardie William D; Stahlman Mildred T; Whitsett Jeffrey A; Korfhagen Thomas R
TGF-alpha perturbs surfactant homeostasis in vivo.
American journal of physiology. Lung cellular and molecular physiology 2005;289(1):L34-43.
2005: Nesslein Lori L; Melton Kristin R; Ikegami Machiko; Na Cheng-Lun; Wert Susan E; Rice Ward R; Whitsett Jeffrey A; Weaver Timothy E
Partial SP-B deficiency perturbs lung function and causes air space abnormalities.
American journal of physiology. Lung cellular and molecular physiology 2005;288(6):L1154-61.
2005: Proskocil Becky J; Sekhon Harmanjatinder S; Clark Jennifer A; Lupo Stacie L; Jia Yibing; Hull William M; Whitsett Jeffrey A; Starcher Barry C; Spindel Eliot R
Vitamin C prevents the effects of prenatal nicotine on pulmonary function in newborn monkeys.
American journal of respiratory and critical care medicine 2005;171(9):1032-9.
2005: Senft Albert P; Korfhagen Thomas R; Whitsett Jeffrey A; Shapiro Steven D; LeVine Ann Marie
Surfactant protein-D regulates soluble CD14 through matrix metalloproteinase-12.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4953-9.
2005: Lappalainen Urpo; Whitsett Jeffrey A; Wert Susan E; Tichelaar Jay W; Bry Kristina
Interleukin-1beta causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung.
American journal of respiratory cell and molecular biology 2005;32(4):311-8.
2005: Wan Huajing; Dingle Sharon; Xu Yan; Besnard Valérie; Kaestner Klaus H; Ang Siew-Lan; Wert Susan; Stahlman Mildred T; Whitsett Jeffrey A
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis.
The Journal of biological chemistry 2005;280(14):13809-16.
2005: Cameron H Scott; Somaschini Marco; Carrera Paola; Hamvas Aaron; Whitsett Jeffrey A; Wert Susan E; Deutsch Gail; Nogee Lawrence M
A common mutation in the surfactant protein C gene associated with lung disease.
The Journal of pediatrics 2005;146(3):370-5.
2005: Ikegami Machiko; Na Cheng-Lun; Korfhagen Thomas R; Whitsett Jeffrey A
Surfactant protein D influences surfactant ultrastructure and uptake by alveolar type II cells.
American journal of physiology. Lung cellular and molecular physiology 2005;288(3):L552-61.
2005: Perl Anne-Karina T; Kist Ralf; Shan Zhengyuan; Scherer Gerd; Whitsett Jeffrey A
Normal lung development and function after Sox9 inactivation in the respiratory epithelium.
Genesis (New York, N.Y. : 2000) 2005;41(1):23-32.
2005: Akeson Ann L; Cameron James E; Le Cras Timothy D; Whitsett Jeffrey A; Greenberg James M
Vascular endothelial growth factor-A induces prenatal neovascularization and alters bronchial development in mice.
Pediatric research 2005;57(1):82-8.
2005: Whitsett Jeffrey A
Surfactant proteins in innate host defense of the lung.
Biology of the neonate 2005;88(3):175-80.
2005: Whitsett Jeffrey A; Wert Susan E; Xu Yan
Genetic disorders of surfactant homeostasis.
Biology of the neonate 2005;87(4):283-7.
2004: Besnard Valérie; Wert Susan E; Hull William M; Whitsett Jeffrey A
Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.
Gene expression patterns : GEP 2004;5(2):193-208.
2004: Wan Huajing; Xu Yan; Ikegami Machiko; Stahlman Mildred T; Kaestner Klaus H; Ang Siew-Lan; Whitsett Jeffrey A
Foxa2 is required for transition to air breathing at birth.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(40):14449-54.
2004: Whitsett Jeffrey A; Wert Susan E; Trapnell Bruce C
Genetic disorders influencing lung formation and function at birth.
Human molecular genetics 2004;13 Spec No 2():R207-15.
2004: Le Cras T D; Hardie W D; Deutsch G H; Albertine K H; Ikegami M; Whitsett J A; Korfhagen T R
Transient induction of TGF-alpha disrupts lung morphogenesis, causing pulmonary disease in adulthood.
American journal of physiology. Lung cellular and molecular physiology 2004;287(4):L718-29.
2004: Miller Leigh-Anne D; Wert Susan E; Clark Jean C; Xu Yan; Perl Anne-Karina T; Whitsett Jeffrey A
Role of Sonic hedgehog in patterning of tracheal-bronchial cartilage and the peripheral lung.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(1):57-71.
2004: Reynolds Paul R; Mucenski Michael L; Le Cras Timothy D; Nichols William C; Whitsett Jeffrey A
Midkine is regulated by hypoxia and causes pulmonary vascular remodeling.
The Journal of biological chemistry 2004;279(35):37124-32.
2004: Davé Vrushank; Childs Tawanna; Whitsett Jeffrey A
Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells.
The Journal of biological chemistry 2004;279(33):34578-88.
2004: LeVine Ann Marie; Elliott James; Whitsett Jeffrey A; Srikiatkhachorn Anon; Crouch Erika; DeSilva Nihal; Korfhagen Thomas
Surfactant protein-d enhances phagocytosis and pulmonary clearance of respiratory syncytial virus.
American journal of respiratory cell and molecular biology 2004;31(2):193-9.
2004: Le Cras T D; Spitzmiller R E; Albertine K H; Greenberg J M; Whitsett J A; Akeson A L
VEGF causes pulmonary hemorrhage, hemosiderosis, and air space enlargement in neonatal mice.
American journal of physiology. Lung cellular and molecular physiology 2004;287(1):L134-42.
2004: Elluru Ravindhra G; Whitsett Jeffrey A
Potential role of Sox9 in patterning tracheal cartilage ring formation in an embryonic mouse model.
Archives of otolaryngology--head & neck surgery 2004;130(6):732-6.
2004: Khoor Andras; Stahlman Mildred T; Johnson Jean M; Olson Sandra J; Whitsett Jeffrey A
Forkhead box A2 transcription factor is expressed in all types of neuroendocrine lung tumors.
Human pathology 2004;35(5):560-4.
2004: Karp Christopher L; Flick Leah M; Park Kiwon W; Softic Samir; Greer Todd M; Keledjian Raquel; Yang Rong; Uddin Jasim; Guggino William B; Atabani Sowsan F; Belkaid Yasmine; Xu Yan; Whitsett Jeffrey A; Accurso Frank J; Wills-Karp Marsha; Petasis Nicos A
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway.
Nature immunology 2004;5(4):388-92.
2004: Park Kwon-Sik; Whitsett Jeffrey A; Di Palma Tina; Hong Jeong-Ho; Yaffe Michael B; Zannini Mariastella
TAZ interacts with TTF-1 and regulates expression of surfactant protein-C.
The Journal of biological chemistry 2004;279(17):17384-90.
2004: Shulenin Sergey; Nogee Lawrence M; Annilo Tarmo; Wert Susan E; Whitsett Jeffrey A; Dean Michael
ABCA3 gene mutations in newborns with fatal surfactant deficiency.
The New England journal of medicine 2004;350(13):1296-303.
2004: Hokuto Isamu; Perl Anne-Karina T; Whitsett Jeffrey A
FGF signaling is required for pulmonary homeostasis following hyperoxia.
American journal of physiology. Lung cellular and molecular physiology 2004;286(3):L580-7.
2004: Kalinichenko Vladimir V; Gusarova Galina A; Kim Il-Man; Shin Brian; Yoder Helena M; Clark Jean; Sapozhnikov Alexander M; Whitsett Jeffrey A; Costa Robert H
Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development.
American journal of physiology. Lung cellular and molecular physiology 2004;286(3):L521-30.
2004: Wan Huajing; Kaestner Klaus H; Ang Siew-Lan; Ikegami Machiko; Finkelman Fred D; Stahlman Mildred T; Fulkerson Patricia C; Rothenberg Marc E; Whitsett Jeffrey A
Foxa2 regulates alveolarization and goblet cell hyperplasia.
Development (Cambridge, England) 2004;131(4):953-64.
2004: Hokuto Isamu; Ikegami Machiko; Yoshida Mitsuhiro; Takeda Kiyoshi; Akira Shizuo; Perl Anne-Karina T; Hull William M; Wert Susan E; Whitsett Jeffrey A
Stat-3 is required for pulmonary homeostasis during hyperoxia.
The Journal of clinical investigation 2004;113(1):28-37.
2004: Yoshida M; Whitsett J A
Interactions between pulmonary surfactant and alveolar macrophages in the pathogenesis of lung disease.
Cellular and molecular biology (Noisy-le-Grand, France) 2004;50 Online Pub():OL639-48.
2003: Trapnell Bruce C; Whitsett Jeffrey A; Nakata Koh
Pulmonary alveolar proteinosis.
The New England journal of medicine 2003;349(26):2527-39.
2003: Akeson Ann L; Greenberg James M; Cameron James E; Thompson Felisa Y; Brooks Sherry K; Wiginton Diane; Whitsett Jeffrey A
Temporal and spatial regulation of VEGF-A controls vascular patterning in the embryonic lung.
Developmental biology 2003;264(2):443-55.
2003: Liu Cong; Ikegami Machiko; Stahlman Mildred T; Dey Chitta R; Whitsett Jeffrey A
Inhibition of alveolarization and altered pulmonary mechanics in mice expressing GATA-6.
American journal of physiology. Lung cellular and molecular physiology 2003;285(6):L1246-54.
2003: Le Cras Timothy D; Hardie William D; Fagan Karen; Whitsett Jeffrey A; Korfhagen Thomas R
Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha.
American journal of physiology. Lung cellular and molecular physiology 2003;285(5):L1046-54.
2003: Mucenski Michael L; Wert Susan E; Nation Jennifer M; Loudy David E; Huelsken Joerg; Birchmeier Walter; Morrisey Edward E; Whitsett Jeffrey A
beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
The Journal of biological chemistry 2003;278(41):40231-8.
2003: DeFelice Mario; Silberschmidt Daniel; DiLauro Roberto; Xu Yan; Wert Susan E; Weaver Timothy E; Bachurski Cindy J; Clark Jean C; Whitsett Jeffrey A
TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression.
The Journal of biological chemistry 2003;278(37):35574-83.
2003: Noah Terry L; Murphy Paula C; Alink Jorien J; Leigh Margaret W; Hull William M; Stahlman Mildred T; Whitsett Jeffrey A
Bronchoalveolar lavage fluid surfactant protein-A and surfactant protein-D are inversely related to inflammation in early cystic fibrosis.
American journal of respiratory and critical care medicine 2003;168(6):685-91.
2003: Melton Kristin R; Nesslein Lori L; Ikegami Machiko; Tichelaar Jay W; Clark Jean C; Whitsett Jeffrey A; Weaver Timothy E
SP-B deficiency causes respiratory failure in adult mice.
American journal of physiology. Lung cellular and molecular physiology 2003;285(3):L543-9.
2003: Chabot Sophie; Koumanov Kamen; Lambeau Gérard; Gelb Michael H; Balloy Viviane; Chignard Michel; Whitsett Jeffrey A; Touqui Lhousseine
Inhibitory effects of surfactant protein A on surfactant phospholipid hydrolysis by secreted phospholipases A2.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):995-1000.
2003: Perl Anne-Karina T; Hokuto Isamu; Impagnatiello Maria-Antonietta; Christofori Gerhard; Whitsett Jeffrey A
Temporal effects of Sprouty on lung morphogenesis.
Developmental biology 2003;258(1):154-68.
2003: Reynolds Paul R; Mucenski Michael L; Whitsett Jeffrey A
Thyroid transcription factor (TTF) -1 regulates the expression of midkine (MK) during lung morphogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;227(2):227-37.
2003: Glasser Stephan W; Detmer Emily A; Ikegami Machiko; Na Cheng-Lun; Stahlman Mildred T; Whitsett Jeffrey A
Pneumonitis and emphysema in sp-C gene targeted mice.
The Journal of biological chemistry 2003;278(16):14291-8.
2003: Collins Rachel A; Ikegami Machiko; Korfhagen Thomas R; Whitsett Jeffrey A; Sly Peter D
In vivo measurements of changes in respiratory mechanics with age in mice deficient in surfactant protein D.
Pediatric research 2003;53(3):463-7.
2003: Epaud Ralph; Ikegami Machiko; Whitsett Jeffrey A; Jobe Alan H; Weaver Timothy E; Akinbi Henry T
Surfactant protein B inhibits endotoxin-induced lung inflammation.
American journal of respiratory cell and molecular biology 2003;28(3):373-8.
2003: Xu Yan; Clark Jean C; Aronow Bruce J; Dey Chitta R; Liu Cong; Wooldridge Jamie L; Whitsett Jeffrey A
Transcriptional adaptation to cystic fibrosis transmembrane conductance regulator deficiency.
The Journal of biological chemistry 2003;278(9):7674-82.
2003: Hokuto Isamu; Perl Anne-Karina T; Whitsett Jeffrey A
Prenatal, but not postnatal, inhibition of fibroblast growth factor receptor signaling causes emphysema.
The Journal of biological chemistry 2003;278(1):415-21.
2002: Whitsett Jeffrey A; Weaver Timothy E
Hydrophobic surfactant proteins in lung function and disease.
The New England journal of medicine 2002;347(26):2141-8.
2002: Berclaz Pierre-Yves; Zsengellér Zsuzsanna; Shibata Yoko; Otake Kazuhisa; Strasbaugh Steven; Whitsett Jeffrey A; Trapnell Bruce C
Endocytic internalization of adenovirus, nonspecific phagocytosis, and cytoskeletal organization are coordinately regulated in alveolar macrophages by GM-CSF and PU.1.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6332-42.
2002: Berclaz Pierre-Yves; Shibata Yoko; Whitsett Jeffrey A; Trapnell Bruce C
GM-CSF, via PU.1, regulates alveolar macrophage Fcgamma R-mediated phagocytosis and the IL-18/IFN-gamma -mediated molecular connection between innate and adaptive immunity in the lung.
Blood 2002;100(12):4193-200.
2002: Zhang Liqian; Ikegami Machiko; Dey Chitta R; Korfhagen Thomas R; Whitsett Jeffrey A
Reversibility of pulmonary abnormalities by conditional replacement of surfactant protein D (SP-D) in vivo.
The Journal of biological chemistry 2002;277(41):38709-13.
2002: Du Ming; Jones Julie R; Lanier Jessica; Keeling Kim M; Lindsey J Russell; Tousson Albert; Bebök Zsuzsa; Whitsett Jeffrey A; Dey Chitta R; Colledge William H; Evans Martin J; Sorscher Eric J; Bedwell David M
Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.
Journal of molecular medicine (Berlin, Germany) 2002;80(9):595-604.
2002: Perl Anne-Karina T; Wert Susan E; Nagy Andras; Lobe Corrinne G; Whitsett Jeffrey A
Early restriction of peripheral and proximal cell lineages during formation of the lung.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10482-7.
2002: Liu Cong; Morrisey Edward E; Whitsett Jeffrey A
GATA-6 is required for maturation of the lung in late gestation.
American journal of physiology. Lung cellular and molecular physiology 2002;283(2):L468-75.
2002: Palaniyar Nades; Zhang Liquian; Kuzmenko Alexander; Ikegami Machiko; Wan Sijue; Wu Huixing; Korfhagen Thomas R; Whitsett Jeffrey A; McCormack Francis X
The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo.
The Journal of biological chemistry 2002;277(30):26971-9.
2002: Kalinichenko Vladimir V; Zhou Yan; Shin Brian; Stolz Donna Beer; Watkins Simon C; Whitsett Jeffrey A; Costa Robert H
Wild-type levels of the mouse Forkhead Box f1 gene are essential for lung repair.
American journal of physiology. Lung cellular and molecular physiology 2002;282(6):L1253-65.
2002: Zhang Liqian; Hartshorn Kevan L; Crouch Erika C; Ikegami Machiko; Whitsett Jeffrey A
Complementation of pulmonary abnormalities in SP-D(-/-) mice with an SP-D/conglutinin fusion protein.
The Journal of biological chemistry 2002;277(25):22453-9.
2002: Whitsett Jeffrey A; Clark Jean C; Picard Lara; Tichelaar Jay W; Wert Susan E; Itoh Nobuyuki; Perl Anne-Karina T; Stahlman Mildred T
Fibroblast growth factor 18 influences proximal programming during lung morphogenesis.
The Journal of biological chemistry 2002;277(25):22743-9.
2002: Whitsett Jeffrey A
Genetic basis of familial interstitial lung disease: misfolding or function of surfactant protein C?
American journal of respiratory and critical care medicine 2002;165(9):1201-2.
2002: Stahlman Mildred T; Gray Mary E; Hull William M; Whitsett Jeffrey A
Immunolocalization of surfactant protein-D (SP-D) in human fetal, newborn, and adult tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(5):651-60.
2002: Yang Honghua; Lu Min Min; Zhang Lili; Whitsett Jeffrey A; Morrisey Edward E
GATA6 regulates differentiation of distal lung epithelium.
Development (Cambridge, England) 2002;129(9):2233-46.
2002: Lim Lorena; Kalinichenko Vladimir V; Whitsett Jeffrey A; Costa Robert H
Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele.
American journal of physiology. Lung cellular and molecular physiology 2002;282(5):L1012-22.
2002: McCormack Francis X; Whitsett Jeffrey A
The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung.
The Journal of clinical investigation 2002;109(6):707-12.
2002: Nogee Lawrence M; Dunbar Alston E; Wert Susan; Askin Frederic; Hamvas Aaron; Whitsett Jeffrey A
Mutations in the surfactant protein C gene associated with interstitial lung disease.
Chest 2002;121(3 Suppl):20S-21S.
2002: Whitsett Jeffrey A
Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repair.
The Journal of clinical investigation 2002;109(5):565-9.
2002: Perl Anne-Karina T; Tichelaar Jay W; Whitsett Jeffrey A
Conditional gene expression in the respiratory epithelium of the mouse.
Transgenic research 2002;11(1):21-9.
2002: Johnston Sonya D; Daniels Christopher B; Cenzato David; Whitsett Jeffrey A; Orgeig Sandra
The pulmonary surfactant system matures upon pipping in the freshwater turtle Chelydra serpentina.
The Journal of experimental biology 2002;205(Pt 3):415-25.
2002: Wert Susan E; Dey Chitta R; Blair Paula A; Kimura Shioko; Whitsett Jeffrey A
Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation.
Developmental biology 2002;242(2):75-87.
2002: Ikegami Machiko; Weaver Timothy E; Conkright Juliana J; Sly Peter D; Ross Gary F; Whitsett Jeffrey A; Glasser Stephan W
Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(2):519-26.
2002: Liu Cong; Glasser Stephan W; Wan Huajing; Whitsett Jeffrey A
GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression.
The Journal of biological chemistry 2002;277(6):4519-25.
2002: Trapnell Bruce C; Whitsett Jeffrey A
Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense.
Annual review of physiology 2002;64():775-802.
2001: Miller L A; Wert S E; Whitsett J A
Immunolocalization of sonic hedgehog (Shh) in developing mouse lung.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(12):1593-604.
2001: Krane C M; Fortner C N; Hand A R; McGraw D W; Lorenz J N; Wert S E; Towne J E; Paul R J; Whitsett J A; Menon A G
Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):14114-9.
2001: LeVine A M; Whitsett J A; Hartshorn K L; Crouch E C; Korfhagen T R
Surfactant protein D enhances clearance of influenza A virus from the lung in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):5868-73.
2001: Shibata Y; Berclaz P Y; Chroneos Z C; Yoshida M; Whitsett J A; Trapnell B C
GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.
Immunity 2001;15(4):557-67.
2001: Ikegami M; Elhalwagi B M; Palaniyar N; Dienger K; Korfhagen T; Whitsett J A; McCormack F X
The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse.
The Journal of biological chemistry 2001;276(42):38542-8.
2001: Ikegami M; Hull W M; Yoshida M; Wert S E; Whitsett J A
SP-D and GM-CSF regulate surfactant homeostasis via distinct mechanisms.
American journal of physiology. Lung cellular and molecular physiology 2001;281(3):L697-703.
2001: Zeng X; Gray M; Stahlman M T; Whitsett J A
TGF-beta1 perturbs vascular development and inhibits epithelial differentiation in fetal lung in vivo.
Developmental dynamics : an official publication of the American Association of Anatomists 2001;221(3):289-301.
2001: Whitsett J A; Glasser S W; Tichelaar J W; Perl A K; Clark J C; Wert S E
Transgenic models for study of lung morphogenesis and repair: Parker B. Francis lecture.
Chest 2001;120(1 Suppl):27S-30S.
2001: Amin R S; Wert S E; Baughman R P; Tomashefski J F; Nogee L M; Brody A S; Hull W M; Whitsett J A
Surfactant protein deficiency in familial interstitial lung disease.
The Journal of pediatrics 2001;139(1):85-92.
2001: Kalinichenko V V; Lim L; Stolz D B; Shin B; Rausa F M; Clark J; Whitsett J A; Watkins S C; Costa R H
Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor.
Developmental biology 2001;235(2):489-506.
2001: Yoshida M; Korfhagen T R; Whitsett J A
Surfactant protein D regulates NF-kappa B and matrix metalloproteinase production in alveolar macrophages via oxidant-sensitive pathways.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7514-9.
2001: Zhang L; Ikegami M; Crouch E C; Korfhagen T R; Whitsett J A
Activity of pulmonary surfactant protein-D (SP-D) in vivo is dependent on oligomeric structure.
The Journal of biological chemistry 2001;276(22):19214-9.
2001: Miller L D; Wert S E; Whitsett J A
Surfactant proteins and cell markers in the respiratory epithelium of the amphibian, Ambystoma mexicanum.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2001;129(1):141-9.
2001: Glasser S W; Burhans M S; Korfhagen T R; Na C L; Sly P D; Ross G F; Ikegami M; Whitsett J A
Altered stability of pulmonary surfactant in SP-C-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6366-71.
2001: Clark J C; Tichelaar J W; Wert S E; Itoh N; Perl A K; Stahlman M T; Whitsett J A
FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L705-15.
2001: Linke M J; Harris C E; Korfhagen T R; McCormack F X; Ashbaugh A D; Steele P; Whitsett J A; Walzer P D
Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.
The Journal of infectious diseases 2001;183(6):943-52.
2001: Zsengellér Z K; Ross G F; Trapnell B C; Szabó C; Whitsett J A
Adenovirus infection increases iNOS and peroxynitrite production in the lung.
American journal of physiology. Lung cellular and molecular physiology 2001;280(3):L503-11.
2001: Yoshida M; Ikegami M; Reed J A; Chroneos Z C; Whitsett J A
GM-CSF regulates protein and lipid catabolism by alveolar macrophages.
American journal of physiology. Lung cellular and molecular physiology 2001;280(3):L379-86.
2001: LeVine A M; Whitsett J A
Pulmonary collectins and innate host defense of the lung.
Microbes and infection / Institut Pasteur 2001;3(2):161-6.
2001: Nogee L M; Dunbar A E; Wert S E; Askin F; Hamvas A; Whitsett J A
A mutation in the surfactant protein C gene associated with familial interstitial lung disease.
The New England journal of medicine 2001;344(8):573-9.
2000: Naltner A; Wert S; Whitsett J A; Yan C
Temporal/spatial expression of nuclear receptor coactivators in the mouse lung.
American journal of physiology. Lung cellular and molecular physiology 2000;279(6):L1066-74.
2000: Chroneos Z C; Wert S E; Livingston J L; Hassett D J; Whitsett J A
Role of cystic fibrosis transmembrane conductance regulator in pulmonary clearance of Pseudomonas aeruginosa in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):3941-50.
2000: LeVine A M; Whitsett J A; Gwozdz J A; Richardson T R; Fisher J H; Burhans M S; Korfhagen T R
Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):3934-40.
2000: Dunbar A E; Wert S E; Ikegami M; Whitsett J A; Hamvas A; White F V; Piedboeuf B; Jobin C; Guttentag S; Nogee L M
Prolonged survival in hereditary surfactant protein B (SP-B) deficiency associated with a novel splicing mutation.
Pediatric research 2000;48(3):275-82.
2000: Ikegami M; Whitsett J A; Jobe A; Ross G; Fisher J; Korfhagen T
Surfactant metabolism in SP-D gene-targeted mice.
American journal of physiology. Lung cellular and molecular physiology 2000;279(3):L468-76.
2000: Hayashida S; Harrod K S; Whitsett J A
Regulation and function of CCSP during pulmonary Pseudomonas aeruginosa infection in vivo.
American journal of physiology. Lung cellular and molecular physiology 2000;279(3):L452-9.
2000: Ikegami M; Jobe A H; Whitsett J; Korfhagen T
Tolerance of SP-A-deficient mice to hyperoxia or exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(2):644-8.
2000: Reed J A; Ikegami M; Robb L; Begley C G; Ross G; Whitsett J A
Distinct changes in pulmonary surfactant homeostasis in common beta-chain- and GM-CSF-deficient mice.
American journal of physiology. Lung cellular and molecular physiology 2000;278(6):L1164-71.
2000: Wert S E; Yoshida M; LeVine A M; Ikegami M; Jones T; Ross G F; Fisher J H; Korfhagen T R; Whitsett J A
Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):5972-7.
2000: Tichelaar J W; Lu W; Whitsett J A
Conditional expression of fibroblast growth factor-7 in the developing and mature lung.
The Journal of biological chemistry 2000;275(16):11858-64.
2000: Harrod K S; Mounday A D; Whitsett J A
Adenoviral E3-14.7K protein in LPS-induced lung inflammation.
American journal of physiology. Lung cellular and molecular physiology 2000;278(4):L631-9.
2000: Stahlman M T; Gray M P; Falconieri M W; Whitsett J A; Weaver T E
Lamellar body formation in normal and surfactant protein B-deficient fetal mice.
Laboratory investigation; a journal of technical methods and pathology 2000;80(3):395-403.
2000: Nogee L M; Wert S E; Proffit S A; Hull W M; Whitsett J A
Allelic heterogeneity in hereditary surfactant protein B (SP-B) deficiency.
American journal of respiratory and critical care medicine 2000;161(3 Pt 1):973-81.
2000: Paine R; Preston A M; Wilcoxen S; Jin H; Siu B B; Morris S B; Reed J A; Ross G; Whitsett J A; Beck J M
Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(5):2602-9.
2000: Fisher J H; Sheftelyevich V; Ho Y S; Fligiel S; McCormack F X; Korfhagen T R; Whitsett J A; Ikegami M
Pulmonary-specific expression of SP-D corrects pulmonary lipid accumulation in SP-D gene-targeted mice.
American journal of physiology. Lung cellular and molecular physiology 2000;278(2):L365-73.
2000: Beck D C; Na C L; Whitsett J A; Weaver T E
Ablation of a critical surfactant protein B intramolecular disulfide bond in transgenic mice.
The Journal of biological chemistry 2000;275(5):3371-6.
2000: Beck D C; Ikegami M; Na C L; Zaltash S; Johansson J; Whitsett J A; Weaver T E
The role of homodimers in surfactant protein B function in vivo.
The Journal of biological chemistry 2000;275(5):3365-70.
2000: Byrd-Gloster A L; Khoor A; Glass L F; Messina J L; Whitsett J A; Livingston S K; Cagle P T
Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor.
Human pathology 2000;31(1):58-62.
2000: Ikegami M; Whitsett J A; Chroneos Z C; Ross G F; Reed J A; Bachurski C J; Jobe A H
IL-4 increases surfactant and regulates metabolism in vivo.
American journal of physiology. Lung cellular and molecular physiology 2000;278(1):L75-80.
2000: Bruno M D; Korfhagen T R; Liu C; Morrisey E E; Whitsett J A
GATA-6 activates transcription of surfactant protein A.
The Journal of biological chemistry 2000;275(2):1043-9.
2000: Naltner A; Ghaffari M; Whitsett J A; Yan C
Retinoic acid stimulation of the human surfactant protein B promoter is thyroid transcription factor 1 site-dependent.
The Journal of biological chemistry 2000;275(1):56-62.
1999: Tokieda K; Ikegami M; Wert S E; Baatz J E; Zou Y; Whitsett J A
Surfactant protein B corrects oxygen-induced pulmonary dysfunction in heterozygous surfactant protein B-deficient mice.
Pediatric research 1999;46(6):708-14.
1999: Ikegami M; Harrod K S; Whitsett J A; Jobe A H
CCSP deficiency does not alter surfactant homeostasis during adenoviral infection.
The American journal of physiology 1999;277(5 Pt 1):L983-7.
1999: Tokieda K; Iwamoto H S; Bachurski C; Wert S E; Hull W M; Ikeda K; Whitsett J A
Surfactant protein-B-deficient mice are susceptible to hyperoxic lung injury.
American journal of respiratory cell and molecular biology 1999;21(4):463-72.
1999: Bruno M D; Whitsett J A; Ross G F; Korfhagen T R
Transcriptional regulation of the murine surfactant protein-A gene by B-Myb.
The Journal of biological chemistry 1999;274(39):27523-8.
1999: Harrod K S; Trapnell B C; Otake K; Korfhagen T R; Whitsett J A
SP-A enhances viral clearance and inhibits inflammation after pulmonary adenoviral infection.
The American journal of physiology 1999;277(3 Pt 1):L580-8.
1999: Tichelaar J W; Lim L; Costa R H; Whitsett J A
HNF-3/forkhead homologue-4 influences lung morphogenesis and respiratory epithelial cell differentiation in vivo.
Developmental biology 1999;213(2):405-17.
1999: Hardie W D; Bejarano P A; Miller M A; Yankaskas J R; Ritter J H; Whitsett J A; Korfhagen T R
Immunolocalization of transforming growth factor alpha and epidermal growth factor receptor in lungs of patients with cystic fibrosis.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 1999;2(5):415-23.
1999: Whitsett J A; Tichelaar J W
Forkhead transcription factor HFH-4 and respiratory epithelial cell differentiation.
American journal of respiratory cell and molecular biology 1999;21(2):153-4.
1999: Sever-Chroneos Z; Bachurski C J; Yan C; Whitsett J A
Regulation of mouse SP-B gene promoter by AP-1 family members.
The American journal of physiology 1999;277(1 Pt 1):L79-88.
1999: Lin S; Na C L; Akinbi H T; Apsley K S; Whitsett J A; Weaver T E
Surfactant protein B (SP-B) -/- mice are rescued by restoration of SP-B expression in alveolar type II cells but not Clara cells.
The Journal of biological chemistry 1999;274(27):19168-74.
1999: Khoor A; Whitsett J A; Stahlman M T; Olson S J; Cagle P T
Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma.
Human pathology 1999;30(6):695-700.
1999: Tichelaar J W; Wert S E; Costa R H; Kimura S; Whitsett J A
HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lung.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(6):823-32.
1999: Reed J A; Ikegami M; Cianciolo E R; Lu W; Cho P S; Hull W; Jobe A H; Whitsett J A
Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice.
The American journal of physiology 1999;276(4 Pt 1):L556-63.
1999: LeVine A M; Gwozdz J; Stark J; Bruno M; Whitsett J; Korfhagen T
Surfactant protein-A enhances respiratory syncytial virus clearance in vivo.
The Journal of clinical investigation 1999;103(7):1015-21.
1999: Sekhon H S; Jia Y; Raab R; Kuryatov A; Pankow J F; Whitsett J A; Lindstrom J; Spindel E R
Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys.
The Journal of clinical investigation 1999;103(5):637-47.
1999: Ghaffari M; Whitsett J A; Yan C
Inhibition of hSP-B promoter in respiratory epithelial cells by a dominant negative retinoic acid receptor.
The American journal of physiology 1999;276(3 Pt 1):L398-404.
1999: Zsengellér Z K; Halbert C; Miller A D; Wert S E; Whitsett J A; Bachurski C J
Keratinocyte growth factor stimulates transduction of the respiratory epithelium by retroviral vectors.
Human gene therapy 1999;10(3):341-53.
1999: LeVine A M; Reed J A; Kurak K E; Cianciolo E; Whitsett J A
GM-CSF-deficient mice are susceptible to pulmonary group B streptococcal infection.
The Journal of clinical investigation 1999;103(4):563-9.
1999: LeVine A M; Kurak K E; Wright J R; Watford W T; Bruno M D; Ross G F; Whitsett J A; Korfhagen T R
Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice.
American journal of respiratory cell and molecular biology 1999;20(2):279-86.
1999: Iwamoto H S; Trapnell B C; McConnell C J; Daugherty C; Whitsett J A
Pulmonary inflammation associated with repeated, prenatal exposure to an E1, E3-deleted adenoviral vector in sheep.
Gene therapy 1999;6(1):98-106.
1999: Shaw-White J R; Bruno M D; Whitsett J A
GATA-6 activates transcription of thyroid transcription factor-1.
The Journal of biological chemistry 1999;274(5):2658-64.
1998: Harlamert H A; Mira J; Bejarano P A; Baughman R P; Miller M A; Whitsett J A; Yassin R
Thyroid transcription factor-1 and cytokeratins 7 and 20 in pulmonary and breast carcinoma.
Acta cytologica 1998;42(6):1382-8.
1998: Harrod K S; Mounday A D; Stripp B R; Whitsett J A
Clara cell secretory protein decreases lung inflammation after acute virus infection.
The American journal of physiology 1998;275(5 Pt 1):L924-30.
1998: Whitsett J A; Glasser S W
Regulation of surfactant protein gene transcription.
Biochimica et biophysica acta 1998;1408(2-3):303-11.
1998: Korfhagen T R; LeVine A M; Whitsett J A
Surfactant protein A (SP-A) gene targeted mice.
Biochimica et biophysica acta 1998;1408(2-3):296-302.
1998: Zeng X; Yutzey K E; Whitsett J A
Thyroid transcription factor-1, hepatocyte nuclear factor-3beta and surfactant protein A and B in the developing chick lung.
Journal of anatomy 1998;193 ( Pt 3)():399-408.
1998: Korfhagen T R; Sheftelyevich V; Burhans M S; Bruno M D; Ross G F; Wert S E; Stahlman M T; Jobe A H; Ikegami M; Whitsett J A; Fisher J H
Surfactant protein-D regulates surfactant phospholipid homeostasis in vivo.
The Journal of biological chemistry 1998;273(43):28438-43.
1998: LeVine A M; Kurak K E; Bruno M D; Stark J M; Whitsett J A; Korfhagen T R
Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection.
American journal of respiratory cell and molecular biology 1998;19(4):700-8.
1998: Ross G F; Bruno M D; Uyeda M; Suzuki K; Nagao K; Whitsett J A; Korfhagen T R
Enhanced reporter gene expression in cells transfected in the presence of DMI-2, an acid nuclease inhibitor.
Gene therapy 1998;5(9):1244-50.
1998: Zsengellér Z K; Reed J A; Bachurski C J; LeVine A M; Forry-Schaudies S; Hirsch R; Whitsett J A
Adenovirus-mediated granulocyte-macrophage colony-stimulating factor improves lung pathology of pulmonary alveolar proteinosis in granulocyte-macrophage colony-stimulating factor-deficient mice.
Human gene therapy 1998;9(14):2101-9.
1998: Harrod K S; Hermiston T W; Trapnell B C; Wold W S; Whitsett J A
Lung-specific expression of adenovirus E3-14.7K in transgenic mice attenuates adenoviral vector-mediated lung inflammation and enhances transgene expression.
Human gene therapy 1998;9(13):1885-98.
1998: Jain-Vora S; LeVine A M; Chroneos Z; Ross G F; Hull W M; Whitsett J A
Interleukin-4 enhances pulmonary clearance of Pseudomonas aeruginosa.
Infection and immunity 1998;66(9):4229-36.
1998: Ikegami M; Korfhagen T R; Whitsett J A; Bruno M D; Wert S E; Wada K; Jobe A H
Characteristics of surfactant from SP-A-deficient mice.
The American journal of physiology 1998;275(2 Pt 1):L247-54.
1998: Yan C; Ghaffari M; Whitsett J A; Zeng X; Sever Z; Lin S
Retinoic acid-receptor activation of SP-B gene transcription in respiratory epithelial cells.
The American journal of physiology 1998;275(2 Pt 1):L239-46.
1998: Stahlman M T; Gray M E; Whitsett J A
Temporal-spatial distribution of hepatocyte nuclear factor-3beta in developing human lung and other foregut derivatives.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(8):955-62.
1998: Reed J A; Whitsett J A
Granulocyte-macrophage colony-stimulating factor and pulmonary surfactant homeostasis.
Proceedings of the Association of American Physicians 1998;110(4):321-32.
1998: Ikegami M; Horowitz A D; Whitsett J A; Jobe A H
Clearance of SP-C and recombinant SP-C in vivo and in vitro.
The American journal of physiology 1998;274(6 Pt 1):L933-9.
1998: Whitsett J A; Stahlman M T
Impact of advances in physiology, biochemistry, and molecular biology on pulmonary disease in neonates.
American journal of respiratory and critical care medicine 1998;157(4 Pt 2):S67-71.
1998: Zeng X; Wert S E; Federici R; Peters K G; Whitsett J A
VEGF enhances pulmonary vasculogenesis and disrupts lung morphogenesis in vivo.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;211(3):215-27.
1998: Sullivan L C; Daniels C B; Phillips I D; Orgeig S; Whitsett J A
Conservation of surfactant protein A: evidence for a single origin for vertebrate pulmonary surfactant.
Journal of molecular evolution 1998;46(2):131-8.
1997: Ghaffari M; Zeng X; Whitsett J A; Yan C
Nuclear localization domain of thyroid transcription factor-1 in respiratory epithelial cells.
The Biochemical journal 1997;328 ( Pt 3)():757-61.
1997: Zhou L; Dey C R; Wert S E; Yan C; Costa R H; Whitsett J A
Hepatocyte nuclear factor-3beta limits cellular diversity in the developing respiratory epithelium and alters lung morphogenesis in vivo.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;210(3):305-14.
1997: Jain-Vora S; Wert S E; Temann U A; Rankin J A; Whitsett J A
Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung.
American journal of respiratory cell and molecular biology 1997;17(5):541-51.
1997: Tokieda K; Whitsett J A; Clark J C; Weaver T E; Ikeda K; McConnell K B; Jobe A H; Ikegami M; Iwamoto H S
Pulmonary dysfunction in neonatal SP-B-deficient mice.
The American journal of physiology 1997;273(4 Pt 1):L875-82.
1997: Huffman Reed J A; Rice W R; Zsengellér Z K; Wert S E; Dranoff G; Whitsett J A
GM-CSF enhances lung growth and causes alveolar type II epithelial cell hyperplasia in transgenic mice.
The American journal of physiology 1997;273(4 Pt 1):L715-25.
1997: Ikegami M; Jobe A H; Huffman Reed J A; Whitsett J A
Surfactant metabolic consequences of overexpression of GM-CSF in the epithelium of GM-CSF-deficient mice.
The American journal of physiology 1997;273(4 Pt 1):L709-14.
1997: Hardie W D; Bruno M D; Huelsman K M; Iwamoto H S; Carrigan P E; Leikauf G D; Whitsett J A; Korfhagen T R
Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha.
The American journal of pathology 1997;151(4):1075-83.
1997: Horowitz A D; Kurak K; Moussavian B; Whitsett J A; Wert S E; Hull W M; McNanie J; Ikegami M
Preferential uptake of small-aggregate fraction of pulmonary surfactant in vitro.
The American journal of physiology 1997;273(2 Pt 1):L468-77.
1997: Zsengellér Z K; Wert S E; Bachurski C J; Kirwin K L; Trapnell B C; Whitsett J A
Recombinant adenoviral vector disrupts surfactant homeostasis in mouse lung.
Human gene therapy 1997;8(11):1331-44.
1997: Horowitz A D; Moussavian B; Han E D; Baatz J E; Whitsett J A
Distinct effects of SP-A and SP-B on endocytosis of SP-C by pulmonary epithelial cells.
The American journal of physiology 1997;273(1 Pt 1):L159-71.
1997: Yan C; Whitsett J A
Protein kinase A activation of the surfactant protein B gene is mediated by phosphorylation of thyroid transcription factor 1.
The Journal of biological chemistry 1997;272(28):17327-32.
1997: Wikenheiser K A; Whitsett J A
Tumor progression and cellular differentiation of pulmonary adenocarcinomas in SV40 large T antigen transgenic mice.
American journal of respiratory cell and molecular biology 1997;16(6):713-23.
1997: Korfhagen T R; Whitsett J A
Transcriptional control in the developing lung. The Parker B. Francis lectureship.
Chest 1997;111(6 Suppl):83S-88S.
1997: Zsengellér Z K; Boivin G P; Sawchuk S S; Trapnell B C; Whitsett J A; Hirsch R
Anti-T cell receptor antibody prolongs transgene expression and reduces lung inflammation after adenovirus-mediated gene transfer.
Human gene therapy 1997;8(8):935-41.
1997: LeVine A M; Bruno M D; Huelsman K M; Ross G F; Whitsett J A; Korfhagen T R
Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(9):4336-40.
1997: Akinbi H T; Breslin J S; Ikegami M; Iwamoto H S; Clark J C; Whitsett J A; Jobe A H; Weaver T E
Rescue of SP-B knockout mice with a truncated SP-B proprotein. Function of the C-terminal propeptide.
The Journal of biological chemistry 1997;272(15):9640-7.
1997: Ikegami M; Korfhagen T R; Bruno M D; Whitsett J A; Jobe A H
Surfactant metabolism in surfactant protein A-deficient mice.
The American journal of physiology 1997;272(3 Pt 1):L479-85.
1997: Zhang L; Wikenheiser K A; Whitsett J A
Limitations of retrovirus-mediated HSV-tk gene transfer to pulmonary adenocarcinoma cells in vitro and in vivo.
Human gene therapy 1997;8(5):563-74.
1997: Zhang L; Whitsett J A; Stripp B R
Regulation of Clara cell secretory protein gene transcription by thyroid transcription factor-1.
Biochimica et biophysica acta 1997;1350(3):359-67.
1997: Khoor A; Whitsett J A; Stahlman M T; Halter S A
Expression of surfactant protein B precursor and surfactant protein B mRNA in adenocarcinoma of the lung.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1997;10(1):62-7.
1997: Clark J C; Weaver T E; Iwamoto H S; Ikegami M; Jobe A H; Hull W M; Whitsett J A
Decreased lung compliance and air trapping in heterozygous SP-B-deficient mice.
American journal of respiratory cell and molecular biology 1997;16(1):46-52.
1996: Zhou L; Graeff R W; McCray P B; Simonet W S; Whitsett J A
Keratinocyte growth factor stimulates CFTR-independent fluid secretion in the fetal lung in vitro.
The American journal of physiology 1996;271(6 Pt 1):L987-94.
1996: Whitsett J A; Zhou L
Use of transgenic mice to study autocrine-paracrine signaling in lung morphogenesis and differentiation.
Clinics in perinatology 1996;23(4):753-69.
1996: Stripp B R; Lund J; Mango G W; Doyen K C; Johnston C; Hultenby K; Nord M; Whitsett J A
Clara cell secretory protein: a determinant of PCB bioaccumulation in mammals.
The American journal of physiology 1996;271(4 Pt 1):L656-64.
1996: Hardie W D; Kerlakian C B; Bruno M D; Huelsman K M; Wert S E; Glasser S W; Whitsett J A; Korfhagen T R
Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor.
American journal of respiratory cell and molecular biology 1996;15(4):499-508.
1996: Zhou L; Lim L; Costa R H; Whitsett J A
Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(10):1183-93.
1996: Korfhagen T R; Bruno M D; Ross G F; Huelsman K M; Ikegami M; Jobe A H; Wert S E; Stripp B R; Morris R E; Glasser S W; Bachurski C J; Iwamoto H S; Whitsett J A
Altered surfactant function and structure in SP-A gene targeted mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9594-9.
1996: Enelow R I; Stoler M H; Srikiatkhachorn A; Kerlakian C; Agersborg S; Whitsett J A; Braciale T J
A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity. Implications for immune-mediated lung disease.
The Journal of clinical investigation 1996;98(4):914-22.
1996: Rankin J A; Picarella D E; Geba G P; Temann U A; Prasad B; DiCosmo B; Tarallo A; Stripp B; Whitsett J; Flavell R A
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7821-5.
1996: Stahlman M T; Gray M E; Whitsett J A
Expression of thyroid transcription factor-1(TTF-1) in fetal and neonatal human lung.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996;44(7):673-8.
1996: Ikeda K; Shaw-White J R; Wert S E; Whitsett J A
Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cells.
Molecular and cellular biology 1996;16(7):3626-36.
1996: Chroneos Z C; Abdolrasulnia R; Whitsett J A; Rice W R; Shepherd V L
Purification of a cell-surface receptor for surfactant protein A.
The Journal of biological chemistry 1996;271(27):16375-83.
1996: Pryhuber G S; Bachurski C; Hirsch R; Bacon A; Whitsett J A
Tumor necrosis factor-alpha decreases surfactant protein B mRNA in murine lung.
The American journal of physiology 1996;270(5 Pt 1):L714-21.
1996: Evans D A; Wilmott R W; Whitsett J A
Surfactant replacement therapy for adult respiratory distress syndrome in children.
Pediatric pulmonology 1996;21(5):328-36.
1996: Zhou L; Dey C R; Wert S E; Whitsett J A
Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-beta 1 chimeric gene.
Developmental biology 1996;175(2):227-38.
1996: Bejarano P A; Baughman R P; Biddinger P W; Miller M A; Fenoglio-Preiser C; al-Kafaji B; Di Lauro R; Whitsett J A
Surfactant proteins and thyroid transcription factor-1 in pulmonary and breast carcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1996;9(4):445-52.
1996: Holzinger A; Dingle S; Bejarano P A; Miller M A; Weaver T E; DiLauro R; Whitsett J A
Monoclonal antibody to thyroid transcription factor-1: production, characterization, and usefulness in tumor diagnosis.
Hybridoma 1996;15(1):49-53.
1996: Wilmott R W; Amin R S; Perez C R; Wert S E; Keller G; Boivin G P; Hirsch R; De Inocencio J; Lu P; Reising S F; Yei S; Whitsett J A; Trapnell B C
Safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lungs of nonhuman primates.
Human gene therapy 1996;7(3):301-18.
1996: Whitsett J A; Korfhagen T R
Regulation of gene transcription in respiratory epithelial cells.
American journal of respiratory cell and molecular biology 1996;14(2):118-20.
1996: Huffman J A; Hull W M; Dranoff G; Mulligan R C; Whitsett J A
Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice.
The Journal of clinical investigation 1996;97(3):649-55.
1996: Horowitz A D; Moussavian B; Whitsett J A
Roles of SP-A, SP-B, and SP-C in modulation of lipid uptake by pulmonary epithelial cells in vitro.
The American journal of physiology 1996;270(1 Pt 1):L69-79.
1995: Simonet W S; DeRose M L; Bucay N; Nguyen H Q; Wert S E; Zhou L; Ulich T R; Thomason A; Danilenko D M; Whitsett J A
Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12461-5.
1995: Holzinger A; Trapnell B C; Weaver T E; Whitsett J A; Iwamoto H S
Intraamniotic administration of an adenoviral vector for gene transfer to fetal sheep and mouse tissues.
Pediatric research 1995;38(6):844-50.
1995: Vorbroker D K; Voorhout W F; Weaver T E; Whitsett J A
Posttranslational processing of surfactant protein C in rat type II cells.
The American journal of physiology 1995;269(6 Pt 1):L727-33.
1995: Yan C; Sever Z; Whitsett J A
Upstream enhancer activity in the human surfactant protein B gene is mediated by thyroid transcription factor 1.
The Journal of biological chemistry 1995;270(42):24852-7.
1995: Whitsett J A; Nogee L M; Weaver T E; Horowitz A D
Human surfactant protein B: structure, function, regulation, and genetic disease.
Physiological reviews 1995;75(4):749-57.
1995: Clark J C; Wert S E; Bachurski C J; Stahlman M T; Stripp B R; Weaver T E; Whitsett J A
Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7794-8.
1995: Bachurski C J; Pryhuber G S; Glasser S W; Kelly S E; Whitsett J A
Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription.
The Journal of biological chemistry 1995;270(33):19402-7.
1995: Vincent M C; Trapnell B C; Baughman R P; Wert S E; Whitsett J A; Iwamoto H S
Adenovirus-mediated gene transfer to the respiratory tract of fetal sheep in utero.
Human gene therapy 1995;6(8):1019-28.
1995: Bruno M A; Bohinski R J; Carter J E; Foss K A; Whitsett J A
Structure and function of the mouse surfactant protein B gene.
The American journal of physiology 1995;268(6 Pt 1):section L following t of c.
1995: Bruno M A; Bohinski R J; Carter J E; Foss K A; Whitsett J A
Structure and function of the mouse surfactant protein B gene.
The American journal of physiology 1995;268(6 Pt 3):section L 2 p following table of contents.
1995: Ikeda K; Clark J C; Shaw-White J R; Stahlman M T; Boutell C J; Whitsett J A
Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells.
The Journal of biological chemistry 1995;270(14):8108-14.
1995: Sternberg R I; Whitsett J A; Hull W M; Baughman R P
Pneumocystis carinii alters surfactant protein A concentrations in bronchoalveolar lavage fluid.
The Journal of laboratory and clinical medicine 1995;125(4):462-9.
1995: Zsengeller Z K; Wert S E; Hull W M; Hu X; Yei S; Trapnell B C; Whitsett J A
Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice.
Human gene therapy 1995;6(4):457-67.
1995: Vorbroker D K; Profitt S A; Nogee L M; Whitsett J A
Aberrant processing of surfactant protein C in hereditary SP-B deficiency.
The American journal of physiology 1995;268(4 Pt 1):L647-56.
1995: Bruno M A; Bohinski R J; Carter J E; Foss K A; Whitsett J A
Structure and function of the mouse surfactant protein B gene.
The American journal of physiology 1995;268(3 Pt 1):L381-9.
1995: Bruno M D; Bohinski R J; Huelsman K M; Whitsett J A; Korfhagen T R
Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1.
The Journal of biological chemistry 1995;270(12):6531-6.
1995: DiCosmo B; Geba G; Picarella D; Elias J A; Rankin J A; Stripp B; Whitsett J A; Flavell R A
Expression of interleukin-6 by airway epithelial cells. Effects on airway inflammation and hyperreactivity in transgenic mice.
Chest 1995;107(3 Suppl):131S.
1995: Ross G F; Morris R E; Ciraolo G; Huelsman K; Bruno M; Whitsett J A; Baatz J E; Korfhagen T R
Surfactant protein A-polylysine conjugates for delivery of DNA to airway cells in culture.
Human gene therapy 1995;6(1):31-40.
1994: Zhou L; Dey C R; Wert S E; DuVall M D; Frizzell R A; Whitsett J A
Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR.
Science (New York, N.Y.) 1994;266(5191):1705-8.
1994: Glasser S W; Korfhagen T R; Wert S E; Whitsett J A
Transgenic models for study of pulmonary development and disease.
The American journal of physiology 1994;267(5 Pt 1):L489-97.
1994: DiCosmo B F; Geba G P; Picarella D; Elias J A; Rankin J A; Stripp B R; Whitsett J A; Flavell R A
Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity.
The Journal of clinical investigation 1994;94(5):2028-35.
1994: Yei S; Bachurski C J; Weaver T E; Wert S E; Trapnell B C; Whitsett J A
Adenoviral-mediated gene transfer of human surfactant protein B to respiratory epithelial cells.
American journal of respiratory cell and molecular biology 1994;11(3):329-36.
1994: Bohinski R J; Di Lauro R; Whitsett J A
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis.
Molecular and cellular biology 1994;14(9):5671-81.
1994: Khoor A; Stahlman M T; Gray M E; Whitsett J A
Temporal-spatial distribution of SP-B and SP-C proteins and mRNAs in developing respiratory epithelium of human lung.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1994;42(9):1187-99.
1994: Ikeda K; Clark J C; Bachurski C J; Wikenheiser K A; Cuppoletti J; Mohanti S; Morris R E; Whitsett J A
Immortalization of subpopulations of respiratory epithelial cells from transgenic mice bearing SV40 large T antigen.
The American journal of physiology 1994;267(3 Pt 1):L309-17.
1994: Pryhuber G S; Church S L; Kroft T; Panchal A; Whitsett J A
3'-untranslated region of SP-B mRNA mediates inhibitory effects of TPA and TNF-alpha on SP-B expression.
The American journal of physiology 1994;267(1 Pt 1):L16-24.
1994: Yei S; Mittereder N; Wert S; Whitsett J A; Wilmott R W; Trapnell B C
In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung.
Human gene therapy 1994;5(6):731-44.
1994: Mittereder N; Yei S; Bachurski C; Cuppoletti J; Whitsett J A; Tolstoshev P; Trapnell B C
Evaluation of the efficacy and safety of in vitro, adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA.
Human gene therapy 1994;5(6):717-29.
1994: Korfhagen T R; Swantz R J; Wert S E; McCarty J M; Kerlakian C B; Glasser S W; Whitsett J A
Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.
The Journal of clinical investigation 1994;93(4):1691-9.
1993: Wikenheiser K A; Vorbroker D K; Rice W R; Clark J C; Bachurski C J; Oie H K; Whitsett J A
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11029-33.
1993: Horowitz A D; Baatz J E; Whitsett J A
Lipid effects on aggregation of pulmonary surfactant protein SP-C studied by fluorescence energy transfer.
Biochemistry 1993;32(37):9513-23.
1993: Khoor A; Gray M E; Hull W M; Whitsett J A; Stahlman M T
Developmental expression of SP-A and SP-A mRNA in the proximal and distal respiratory epithelium in the human fetus and newborn.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1993;41(9):1311-9.
1993: Sawaya P L; Stripp B R; Whitsett J A; Luse D S
The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 families.
Molecular and cellular biology 1993;13(7):3860-71.
1993: Bohinski R J; Huffman J A; Whitsett J A; Lattier D L
Cis-active elements controlling lung cell-specific expression of human pulmonary surfactant protein B gene.
The Journal of biological chemistry 1993;268(15):11160-6.
1993: Wert S E; Glasser S W; Korfhagen T R; Whitsett J A
Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice.
Developmental biology 1993;156(2):426-43.
1993: Whitsett J A
Training for an academic career in neonatal medicine.
Clinics in perinatology 1993;20(1):1-8.
1993: Baughman R P; Sternberg R I; Hull W; Buchsbaum J A; Whitsett J
Decreased surfactant protein A in patients with bacterial pneumonia.
The American review of respiratory disease 1993;147(3):653-7.
1992: Baatz J E; Smyth K L; Whitsett J A; Baxter C; Absolom D R
Structure and functions of a dimeric form of surfactant protein SP-C: a Fourier transform infrared and surfactometry study.
Chemistry and physics of lipids 1992;63(1-2):91-104.
1992: Korfhagen T R; Bruno M D; Glasser S W; Ciraolo P J; Whitsett J A; Lattier D L; Wikenheiser K A; Clark J C
Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.
The American journal of physiology 1992;263(5 Pt 1):L546-54.
1992: Wispé J R; Warner B B; Clark J C; Dey C R; Neuman J; Glasser S W; Crapo J D; Chang L Y; Whitsett J A
Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury.
The Journal of biological chemistry 1992;267(33):23937-41.
1992: Stahlman M T; Gray M E; Whitsett J A
The ontogeny and distribution of surfactant protein B in human fetuses and newborns.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992;40(10):1471-80.
1992: Wikenheiser K A; Clark J C; Linnoila R I; Stahlman M T; Whitsett J A
Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice.
Cancer research 1992;52(19):5342-52.
1992: Whitsett J A; Dey C R; Stripp B R; Wikenheiser K A; Clark J C; Wert S E; Gregory R J; Smith A E; Cohn J A; Wilson J M
Human cystic fibrosis transmembrane conductance regulator directed to respiratory epithelial cells of transgenic mice.
Nature genetics 1992;2(1):13-20.
1992: Stripp B R; Sawaya P L; Luse D S; Wikenheiser K A; Wert S E; Huffman J A; Lattier D L; Singh G; Katyal S L; Whitsett J A
cis-acting elements that confer lung epithelial cell expression of the CC10 gene.
The Journal of biological chemistry 1992;267(21):14703-12.
1992: Horowitz A D; Elledge B; Whitsett J A; Baatz J E
Effects of lung surfactant proteolipid SP-C on the organization of model membrane lipids: a fluorescence study.
Biochimica et biophysica acta 1992;1107(1):44-54.
1992: Whitsett J A; Clark J C; Wispé J R; Pryhuber G S
Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro.
The American journal of physiology 1992;262(6 Pt 1):L688-93.
1992: Thorkelsson T; Ciraolo G M; Ross G F; Whitsett J A; Morris R E
Lectin activity of the major surfactant protein (SP-A) may participate in, but is not required for, binding to rat type II cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992;40(5):643-9.
1992: Stahlman M T; Gray M E; Ross G F; Hull W M; Wikenheiser K; Dingle S; Zelenski-Low K R; Whitsett J A
Human surfactant protein-A contains blood group A antigenic determinants.
Pediatric research 1992;31(4 Pt 1):364-71.
1992: Vorbroker D K; Dey C; Weaver T E; Whitsett J A
Surfactant protein C precursor is palmitoylated and associates with subcellular membranes.
Biochimica et biophysica acta 1992;1105(1):161-9.
1992: Whitsett J A; Budden A; Hull W M; Clark J C; O'Reilly M A
Transforming growth factor-beta inhibits surfactant protein A expression in vitro.
Biochimica et biophysica acta 1992;1123(3):257-62.
1992: D'Amore-Bruno M A; Wikenheiser K A; Carter J E; Clark J C; Whitsett J A
Sequence, ontogeny, and cellular localization of murine surfactant protein B mRNA.
The American journal of physiology 1992;262(1 Pt 1):L40-7.
1992: Wikenheiser K A; Wert S E; Wispé J R; Stahlman M; D'Amore-Bruno M; Singh G; Katyal S L; Whitsett J A
Distinct effects of oxygen on surfactant protein B expression in bronchiolar and alveolar epithelium.
The American journal of physiology 1992;262(1 Pt 1):L32-9.
1991: Baatz J E; Sarin V; Absolom D R; Baxter C; Whitsett J A
Effects of surfactant-associated protein SP-B synthetic analogs on the structure and surface activity of model membrane bilayers.
Chemistry and physics of lipids 1991;60(2):163-78.
1991: Pryhuber G S; Hull W M; Fink I; McMahan M J; Whitsett J A
Ontogeny of surfactant proteins A and B in human amniotic fluid as indices of fetal lung maturity.
Pediatric research 1991;30(6):597-605.
1991: Glasser S W; Korfhagen T R; Wert S E; Bruno M D; McWilliams K M; Vorbroker D K; Whitsett J A
Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice.
The American journal of physiology 1991;261(4 Pt 1):L349-56.
1991: Korfhagen T R; Glasser S W; Bruno M D; McMahan M J; Whitsett J A
A portion of the human surfactant protein A (SP-A) gene locus consists of a pseudogene.
American journal of respiratory cell and molecular biology 1991;4(5):463-9.
1991: Whitsett J A; Hull W M; Luse S
Failure to detect surfactant protein-specific antibodies in sera of premature infants treated with survanta, a modified bovine surfactant.
Pediatrics 1991;87(4):505-10.
1991: O'Reilly M A; Clark J C; Whitsett J A
Glucocorticoid enhances pulmonary surfactant protein B gene transcription.
The American journal of physiology 1991;260(2 Pt 1):L37-43.
1991: Nogee L M; Wispé J R; Clark J C; Weaver T E; Whitsett J A
Increased expression of pulmonary surfactant proteins in oxygen-exposed rats.
American journal of respiratory cell and molecular biology 1991;4(2):102-7.
1991: Weaver T E; Whitsett J A
Function and regulation of expression of pulmonary surfactant-associated proteins.
The Biochemical journal 1991;273(Pt 2)():249-64.
1991: Ross G F; Sawyer J; O'Connor T; Whitsett J A
Intermolecular cross-links mediate aggregation of phospholipid vesicles by pulmonary surfactant protein SP-A.
Biochemistry 1991;30(3):858-65.
1990: Glasser S W; Korfhagen T R; Bruno M D; Dey C; Whitsett J A
Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse.
The Journal of biological chemistry 1990;265(35):21986-91.
1990: Pryhuber G S; O'Reilly M A; Clark J C; Hull W M; Fink I; Whitsett J A
Phorbol ester inhibits surfactant protein SP-A and SP-B expression.
The Journal of biological chemistry 1990;265(34):20822-8.
1990: Wispé J R; Clark J C; Warner B B; Fajardo D; Hull W E; Holtzman R B; Whitsett J A
Tumor necrosis factor-alpha inhibits expression of pulmonary surfactant protein.
The Journal of clinical investigation 1990;86(6):1954-60.
1990: Stripp B R; Whitsett J A; Lattier D L
Strategies for analysis of gene expression: pulmonary surfactant proteins.
The American journal of physiology 1990;259(4 Pt 1):L185-97.
1990: Korfhagen T R; Glasser S W; Wert S E; Bruno M D; Daugherty C C; McNeish J D; Stock J L; Potter S S; Whitsett J A
Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6122-6.
1990: Baatz J E; Elledge B; Whitsett J A
Surfactant protein SP-B induces ordering at the surface of model membrane bilayers.
Biochemistry 1990;29(28):6714-20.
1990: Sarin V K; Gupta S; Leung T K; Taylor V E; Ohning B L; Whitsett J A; Fox J L
Biophysical and biological activity of a synthetic 8.7-kDa hydrophobic pulmonary surfactant protein SP-B.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2633-7.
1989: O'Reilly M A; Gazdar A F; Clark J C; Pilot-Matias T J; Wert S E; Hull W M; Whitsett J A
Glucocorticoids regulate surfactant protein synthesis in a pulmonary adenocarcinoma cell line.
The American journal of physiology 1989;257(6 Pt 1):L385-92.
1989: Rice W R; Sarin V K; Fox J L; Baatz J; Wert S; Whitsett J A
Surfactant peptides stimulate uptake of phosphatidylcholine by isolated cells.
Biochimica et biophysica acta 1989;1006(2):237-45.
1989: Nogee L M; Wispé J R; Clark J C; Whitsett J A
Increased synthesis and mRNA of surfactant protein A in oxygen-exposed rats.
American journal of respiratory cell and molecular biology 1989;1(2):119-25.
1989: Weaver T E; Whitsett J A
Processing of hydrophobic pulmonary surfactant protein B in rat type II cells.
The American journal of physiology 1989;257(2 Pt 1):L100-8.
1989: O'Reilly M A; Weaver T E; Pilot-Matias T J; Sarin V K; Gazdar A F; Whitsett J A
In vitro translation, post-translational processing and secretion of pulmonary surfactant protein B precursors.
Biochimica et biophysica acta 1989;1011(2-3):140-8.
1989: Ryan R M; Morris R E; Rice W R; Ciraolo G; Whitsett J A
Binding and uptake of pulmonary surfactant protein (SP-A) by pulmonary type II epithelial cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(4):429-40.
1989: Pilot-Matias T J; Kister S E; Fox J L; Kropp K; Glasser S W; Whitsett J A
Structure and organization of the gene encoding human pulmonary surfactant proteolipid SP-B.
DNA (Mary Ann Liebert, Inc.) 1989;8(2):75-86.
1989: Wispé J R; Clark J C; Burhans M S; Kropp K E; Korfhagen T R; Whitsett J A
Synthesis and processing of the precursor for human mangano-superoxide dismutase.
Biochimica et biophysica acta 1989;994(1):30-6.
1988: Nogee L; McMahan M; Whitsett J A
Hyaline membrane disease and surfactant protein, SAP-35, in diabetes in pregnancy.
American journal of perinatology 1988;5(4):374-7.
1988: Weaver T E; Sarin V K; Sawtell N; Hull W M; Whitsett J A
Identification of surfactant proteolipid SP-B in human surfactant and fetal lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(2):982-7.
1988: Weaver T E; Whitsett J A
Structure and function of pulmonary surfactant proteins.
Seminars in perinatology 1988;12(3):213-20.
1988: Glasser S W; Korfhagen T R; Perme C M; Pilot-Matias T J; Kister S E; Whitsett J A
Two SP-C genes encoding human pulmonary surfactant proteolipid.
The Journal of biological chemistry 1988;263(21):10326-31.
1988: O'Reilly M A; Gazdar A F; Morris R E; Whitsett J A
Differential effects of glucocorticoid on expression of surfactant proteins in a human lung adenocarcinoma cell line.
Biochimica et biophysica acta 1988;970(2):194-204.
1988: O'Reilly M A; Nogee L; Whitsett J A
Requirement of the collagenous domain for carbohydrate processing and secretion of a surfactant protein, SP-A.
Biochimica et biophysica acta 1988;969(2):176-84.
1988: Glasser S W; Korfhagen T R; Weaver T E; Clark J C; Pilot-Matias T; Meuth J; Fox J L; Whitsett J A
cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL(pVal).
The Journal of biological chemistry 1988;263(1):9-12.
1987: Whitsett J A; Weaver T E; Clark J C; Sawtell N; Glasser S W; Korfhagen T R; Hull W M
Glucocorticoid enhances surfactant proteolipid Phe and pVal synthesis and RNA in fetal lung.
The Journal of biological chemistry 1987;262(32):15618-23.
1987: Rice W R; Ross G F; Singleton F M; Dingle S; Whitsett J A
Surfactant-associated protein inhibits phospholipid secretion from type II cells.
Journal of applied physiology (Bethesda, Md. : 1985) 1987;63(2):692-8.
1987: McMahan M J; Mimouni F; Miodovnik M; Hull W M; Whitsett J A
Surfactant associated protein (SAP-35) in amniotic fluid from diabetic and nondiabetic pregnancies.
Obstetrics and gynecology 1987;70(1):94-8.
1987: Glasser S W; Korfhagen T R; Weaver T; Pilot-Matias T; Fox J L; Whitsett J A
cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe).
Proceedings of the National Academy of Sciences of the United States of America 1987;84(12):4007-11.
1987: Whitsett J A
Molecular approaches to study of surfactant protein structure and function.
Mead Johnson Symposium on Perinatal and Developmental Medicine 1987;(29):35-9.
1985: Weaver T E; Hull W M; Ross G F; Whitsett J A
Intracellular and oligomeric forms of surfactant-associated apolipoproteins(s) A in the rat.
Biochimica et biophysica acta 1985;827(3):260-7.

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