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Ian Whittle

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Ian R Whittle; Jia X Lim
Overcoming fear and anxiety during awake resection of brain tumours: family support can be pivotal to a successful outcome.
Krzysztof J Gorgolewski; Amos Storkey; Joanna M Wardlaw; Ian R Whittle; Mark E Bastin; Cyril R Pernet
A test-retest fMRI dataset for motor, language and spatial attention functions.
Ian R Whittle; Shaemala Anpalakhan; Fungai Dengu; Jennifer Scotland; Ian J Deary
Preoperative quality of life in patients with degenerative spinal disorders: many are worse than patients with brain tumours and cancer.

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All Publications

2013: Ian R Whittle; Jia X Lim
Overcoming fear and anxiety during awake resection of brain tumours: family support can be pivotal to a successful outcome.
British journal of neurosurgery 2013;27(1):117-8.
2013: Krzysztof J Gorgolewski; Amos Storkey; Joanna M Wardlaw; Ian R Whittle; Mark E Bastin; Cyril R Pernet
A test-retest fMRI dataset for motor, language and spatial attention functions.
GigaScience 2013;2(1):6.
2012: Ian R Whittle; Shaemala Anpalakhan; Fungai Dengu; Jennifer Scotland; Ian J Deary
Preoperative quality of life in patients with degenerative spinal disorders: many are worse than patients with brain tumours and cancer.
British journal of neurosurgery 2012;26(4):460-5.
2012: Stephen J Price; Ian R Whittle; Keyoumars Ashkan; Garth Cruickshank; Paul Grundy
NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice.
British journal of neurosurgery 2012;26(3):331-5.
2010: Ian R Whittle; Neo Stavrinos; Hazem Akil; Yh Yau; Steff Lewis
Assessment of physiological parameters within glioblastomas in awake patients: a prospective clinical study.
British journal of neurosurgery 2010;24(4):447-53.
2010: H Anne Leaver; Maria Teresa Rizzo; Ian R Whittle
Glioma cell death: cell-cell interactions and signalling networks.
Molecular neurobiology 2010;42(1):89-96.
2010: Bartlomiej B Ordys; Séverine Launay; Ruth F Deighton; James McCulloch; Ian R Whittle
The role of mitochondria in glioma pathophysiology.
Molecular neurobiology 2010;42(1):64-75.
2010: Ruth F Deighton; Richard McGregor; Jocelyn Kemp; James McCulloch; Ian R Whittle
Glioma pathophysiology: insights emerging from proteomics.
Brain pathology (Zurich, Switzerland) 2010;20(4):691-703.
2010: Paul A Armitage; Chris Schwindack; Mark E Bastin; Ian R Whittle
Pretreatment tumoural perfusion correlates with an imaging-based response to dexamethasone in patients with glioblastoma multiforme.
Journal of neurology, neurosurgery, and psychiatry 2010;81(4):446-8.
2010: Ruth F Deighton; Lorraine E Kerr; Duncan M Short; Mike Allerhand; Ian R Whittle; James McCulloch
Network generation enhances interpretation of proteomic data from induced apoptosis.
Proteomics 2010;10(6):1307-15.
2010: Kate El Bouzidi; Susan Duncan; Ian R Whittle; Christopher R Butler
Lesional reflex epilepsy associated with the thought of food.
Neurology 2010;74(7):610-2.
2010: Ian R Whittle
What is the place of conservative management for adult supratentorial low-grade glioma?
Advances and technical standards in neurosurgery 2010;35():65-79.
2009: Sara C Erridge; David S Conkey; Diane Stockton; Mark W J Strachan; Patrick F X Statham; Ian R Whittle; Robin Grant; Gillian R Kerr; Anna Gregor
Radiotherapy for pituitary adenomas: long-term efficacy and toxicity.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;93(3):597-601.
2009: Jennifer L Scotland; Rustam Al-Shahi Salman; Ian J Deary; Ian R Whittle
Recruitment difficulties in brain tumour patients cause participation bias: findings from a neuropsychological study of adult inpatients with supratentorial intracranial tumours.
Acta neurochirurgica 2009;151(10):1191-5.
2009: Ruth F Deighton; Duncan M Short; Richard J McGregor; Alan J Gow; Ian R Whittle; James McCulloch
The utility of functional interaction and cluster analysis in CNS proteomics.
Journal of neuroscience methods 2009;180(2):321-9.
2009: S Amarasingh; Malcolm R Macleod; Ian R Whittle
What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.
Journal of neuro-oncology 2009;91(2):117-25.
2008: P M Brennan; Ian R Whittle
Intrathecal baclofen therapy for neurological disorders: a sound knowledge base but many challenges remain.
British journal of neurosurgery 2008;22(4):508-19.
2008: L-Y Ooi; B R Walker; P A Bodkin; Ian R Whittle
Idiopathic intracranial hypertension: can studies of obesity provide the key to understanding pathogenesis?
British journal of neurosurgery 2008;22(2):187-94.
2008: N G Stavrinos; R Taylor; A Rowe; Ian R Whittle
Posterior fossa surgery complicated by a pseudomeningocele, bilateral subdural hygromata and cerebellar cognitive affective syndrome.
British journal of neurosurgery 2008;22(1):107-9.
2008: Ioannis P Fouyas; P Brennan; Paul A T Kelly; Ian R Whittle
The role of endothelin in the cerebrovascular response following intracerebral haemorrhage: experimental studies using the endothelin antagonist SB209670.
British journal of neurosurgery 2008;22(1):35-9.
2007: Ian R Whittle; D M Short; R F Deighton; L E Kerr; C Smith; J McCulloch
Proteomic analysis of gliomas.
British journal of neurosurgery 2007;21(6):576-82.
2007: J Ross; Ian R Whittle; S Fleming; Kathreena M Kurian
Cerebral metastasis of peripheral primitive neuroectodermal tumour (pPNET) - use of cytogenetic abnormalities in diagnosis.
Neuropathology and applied neurobiology 2007;33(4):471-4.
2007: Paul A Armitage; Chris Schwindack; Mark E Bastin; Ian R Whittle
Quantitative assessment of intracranial tumor response to dexamethasone using diffusion, perfusion and permeability magnetic resonance imaging.
Magnetic resonance imaging 2007;25(3):303-10.
2006: L Zbinden; R Pandey; Chris Schwindack; I J Deary; Ian R Whittle
Information processing in patients with intracranial tumours: A preliminary evaluation of the clinical utility of inspection time.
British journal of neurosurgery 2006;20(4):203-8.
2006: Troy Payner; helen Leaver; Brian Knapp; Ian R Whittle; Ovidiu C Trifan; Steven Miller; Maria Teresa Rizzo
Microsomal prostaglandin E synthase-1 regulates human glioma cell growth via prostaglandin E(2)-dependent activation of type II protein kinase A.
Molecular cancer therapeutics 2006;5(7):1817-26.
2006: V Kumar; E W K Peng; MO Fitzpatrick; Ian R Whittle
Tectal plate cyst in adults.
Acta neurochirurgica 2006;148(7):805-8; discussion 808.
2006: Ian R Whittle; R S G Knight; Robert G Will
Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease.
Acta neurochirurgica 2006;148(6):677-9; discussion 679.
2006: H Akil; Patrick F X Statham; M Götz; P Bramley; Ian R Whittle
Adult cerebellar mutism and cognitive-affective syndrome caused by cystic hemangioblastoma.
Acta neurochirurgica 2006;148(5):597-8.
2006: E W K Peng; Kathreena M Kurian; James W Ironside; J Macmullen-Price; MO Fitzpatrick; Ian R Whittle
An intramedullary vascular malformation mimicking intrinsic spinal cord tumour.
British journal of neurosurgery 2006;20(2):109-10.
2006: V Kumar; E W K Peng; Kathreena M Kurian; C Smith; MO Fitzpatrick; Ian R Whittle
An unusual progression of benign thoracic spinal cord teratoma in pregnancy: a hormonally-mediated pathway?
British journal of neurosurgery 2006;20(2):106-8.
2006: Megan C Holmes; M Sangra; Karen L French; Ian R Whittle; J Paterson; John J Mullins; Jonathan R Seckl
11beta-Hydroxysteroid dehydrogenase type 2 protects the neonatal cerebellum from deleterious effects of glucocorticoids.
Neuroscience 2006;137(3):865-73.
2005: Helen S Bell; Ian R Whittle; S A Bader; SB Wharton
Discovery of a perinecrotic 60 kDa MDM2 isoform within glioma spheroids and glioblastoma biopsy material.
Neuropathology and applied neurobiology 2005;31(2):191-202.
2005: Ian R Whittle; S Midgley; H Georges; AM Pringle; R Taylor
Patient perceptions of "awake" brain tumour surgery.
Acta neurochirurgica 2005;147(3):275-7; discussion 277.
2005: Chris Schwindack; E Siminotto; M Meyer; A McNamara; I Marshall; Joanna Wardlaw; Ian R Whittle
Real-time functional magnetic resonance imaging (rt-fMRI) in patients with brain tumours: preliminary findings using motor and language paradigms.
British journal of neurosurgery 2005;19(1):25-32.
2005: YH Yau; Ian Piper; Charles F Contant; Laurence Dunn; Ian R Whittle
Assessment of different data representations and averaging methods on the Spiegelberg compliance device.
Acta neurochirurgica. Supplement 2005;95():289-92.
2004: S Sinha; Mark E Bastin; Joanna Wardlaw; Paul A Armitage; Ian R Whittle
Effects of dexamethasone on peritumoural oedematous brain: a DT-MRI study.
Journal of neurology, neurosurgery, and psychiatry 2004;75(11):1632-5.
2004: Ian R Whittle
The dilemma of low grade glioma.
Journal of neurology, neurosurgery, and psychiatry 2004;75 Suppl 2():ii31-6.
2004: Ian R Whittle; Colin Smith; Parthiban Navoo; Donald A Collie
Meningiomas.
Lancet 2004;363(9420):1535-43.
2004: helen Leaver; JR Williams; C Smith; Ian R Whittle
Intracellular oxidation by human glioma cell populations: effect of arachidonic acid.
Prostaglandins, leukotrienes, and essential fatty acids 2004;70(5):449-53.
2003: Shom Goel; Stephen B Wharton; Laurence P Brett; Ian R Whittle
Morphological changes and stress responses in neurons in cerebral cortex infiltrated by diffuse astrocytoma.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(4):262-70.
2003: Mark E Bastin; S Sinha; Andrew Farrall; Joanna Wardlaw; Ian R Whittle
Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study.
Journal of neurology, neurosurgery, and psychiatry 2003;74(12):1693-6.
2003: Ian R Whittle; S Lyles; M Walker
Gliadel therapy given for first resection of malignant glioma: a single centre study of the potential use of Gliadel.
British journal of neurosurgery 2003;17(4):352-4.
2003: M Walker; J Brown; K Brown; Anna Gregor; Ian R Whittle; Robert Grant
Practical problems with the collection and interpretation of serial quality of life assessments in patients with malignant glioma.
Journal of neuro-oncology 2003;63(2):179-86.
2003: Ian R Whittle; S Borthwick; N Haq
Brain dysfunction following 'awake' craniotomy, brain mapping and resection of glioma.
British journal of neurosurgery 2003;17(2):130-7.
2003: Jun Shinoda; Katherine E McLaughlin; Helen S Bell; Gopal R Swaroop; Shin-Ichi Yamaguchi; Megan C Holmes; Ian R Whittle
Molecular mechanisms underlying dexamethasone inhibition of iNOS expression and activity in C6 glioma cells.
Glia 2003;42(1):68-76.
2003: J Hooper; Ian R Whittle
Costs of thalamic deep brain stimulation for movement disorders in patients with multiple sclerosis.
British journal of neurosurgery 2003;17(1):40-5.
2003: Ioannis P Fouyas; Paul A T Kelly; Isobel M Ritchie; G A Lammie; Ian R Whittle
Cerebrovascular responses to pathophysiological insult in diabetic rats.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2003;10(1):88-91.
2002: D Bell; Robert Grant; D Collie; M Walker; Ian R Whittle
How well do radiologists diagnose intracerebral tumour histology on CT? Findings from a prospective multicentre study.
British journal of neurosurgery 2002;16(6):573-7.
2002: S Yamaguchi; Helen S Bell; J Shinoda; Megan C Holmes; SB Wharton; Ian R Whittle
Glioma tumourgenicity is decreased by iNOS knockout: experimental studies using the C6 striatal implantation glioma model.
British journal of neurosurgery 2002;16(6):567-72.
2002: Ian R Whittle
Surgery for gliomas.
Current opinion in neurology 2002;15(6):663-9.
2002: J Ross; M G J O'Sullivan; Ian S Grant; Robin J Sellar; Ian R Whittle
Impact of early endovascular aneurysmal occlusion on outcome of patients in poor grade after subarachnoid haemorrhage: a prospective, consecutive study.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2002;9(6):648-52.
2002: helen Leaver; SB Wharton; Helen S Bell; I M M Leaver-Yap; Ian R Whittle
Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology.
Prostaglandins, leukotrienes, and essential fatty acids 2002;67(5):283-92.
2002: Ian R Whittle; N Basu; Robert Grant; M Walker; Anna Gregor
Management of patients aged >60 years with malignant glioma: good clinical status and radiotherapy determine outcome.
British journal of neurosurgery 2002;16(4):343-7.
2002: J Hooper; R Taylor; B Pentland; Ian R Whittle
A prospective study of thalamic deep brain stimulation for the treatment of movement disorders in multiple sclerosis.
British journal of neurosurgery 2002;16(2):102-9.
2002: Saurabh Sinha; Mark E Bastin; Ian R Whittle; Joanna Wardlaw
Diffusion tensor MR imaging of high-grade cerebral gliomas.
AJNR. American journal of neuroradiology 2002;23(4):520-7.
2002: S B Wharton; K K Chan; Ian R Whittle
Microtubule-associated protein 2 (MAP-2) is expressed in low and high grade diffuse astrocytomas.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2002;9(2):165-9.
2002: YH Yau; Ian Piper; RE Clutton; Ian R Whittle
An experimental evaluation of a new intraparenchymal continuous compliance probe: preliminary studies.
Acta neurochirurgica. Supplement 2002;81():181-2.
2002: YH Yau; Ian Piper; Charles F Contant; L T Dunn; Ian R Whittle
Clinical experience in the use of the Spiegelberg automated compliance device in the assessment of patients with hydrocephalus.
Acta neurochirurgica. Supplement 2002;81():171-2.
2002: YH Yau; Ian Piper; Charles F Contant; Giuseppe Citerio; Karl L Kiening; Per Enblad; Pelle Nilsson; S Ng; J Wasserberg; Michael Kiefer; Wilson Poon; Laurence Dunn; Ian R Whittle
Multi-centre assessment of the Spiegelberg compliance monitor: interim results.
Acta neurochirurgica. Supplement 2002;81():167-70.
2002: helen Leaver; Helen S Bell; Maria Teresa Rizzo; James W Ironside; A Gregor; SB Wharton; Ian R Whittle
Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(1):19-29.
2002: helen Leaver; Maria Teresa Rizzo; Ian R Whittle
Antitumour actions of highly unsaturated fatty acids: cell signalling and apoptosis.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(1):1-3.
2001: J Hooper; P Simpson; Ian R Whittle
Chronic posttraumatic movement disorder alleviated by insertion of meso-diencephalic deep brain stimulating electrode.
British journal of neurosurgery 2001;15(5):435-8.
2001: stephen lo; Helen S Bell; S Yamaguchi; SB Wharton; Ian R Whittle
Heme oxygenase (HO) isoforms in experimental C6 glioma: an immunocytochemical study.
British journal of neurosurgery 2001;15(5):416-8.
2001: Ian R Whittle; Paul A T Kelly
Mechanisms of peritumoural brain dysfunction: metabolic and neuroreceptor findings in striatal C6 glioma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2001;8(5):430-4.
2001: Helen S Bell; Ian R Whittle; M Walker; helen Leaver; SB Wharton
The development of necrosis and apoptosis in glioma: experimental findings using spheroid culture systems.
Neuropathology and applied neurobiology 2001;27(4):291-304.
2001: J Shinoda; Ian R Whittle
Nitric oxide and glioma: a target for novel therapy?
British journal of neurosurgery 2001;15(3):213-20.
2001: G R Swaroops; Paul A T Kelly; Megan C Holmes; J Shinoda; Ian R Whittle
The effects of dexamethasone therapy on permeability, blood flow and iNOS expression in experimental glioma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2001;8(1):35-9.
2000: Gopal R Swaroop; Paul A T Kelly; Helen S Bell; J Shinoda; S Yamaguchi; Ian R Whittle
The effects of chronic nitric oxide synthase suppression on glioma pathophysiology.
British journal of neurosurgery 2000;14(6):543-8.
2000: SB Wharton; U McNelis; Helen S Bell; Ian R Whittle
Expression of poly(ADP-ribose) polymerase and distribution of poly(ADP-ribosyl)ation in glioblastoma and in a glioma multicellular tumour spheroid model.
Neuropathology and applied neurobiology 2000;26(6):528-35.
2000: YH Yau; Ian Piper; RE Clutton; Ian R Whittle
Experimental evaluation of the Spiegelberg intracranial pressure and intracranial compliance monitor. Technical note.
Journal of neurosurgery 2000;93(6):1072-7.
2000: S B Wharton; G Alistair Lammie; D A Collie; Ian R Whittle
The significance of intratumoural neurones and neuronal differentiation in diffuse gliomas: a case series.
Acta neuropathologica 2000;100(6):695-700.
2000: Ian Piper; Laurence Dunn; Charles F Contant; YH Yau; Ian R Whittle; Giuseppe Citerio; Karl L Kiening; W Schvning; S Ng; Wilson Poon; Per Enblad; Pelle Nilsson
Multi-centre assessment of the Spiegelberg compliance monitor: preliminary results.
Acta neurochirurgica. Supplement 2000;76():491-4.
2000: A Beaumont; Ian R Whittle
The pathogenesis of tumour associated epilepsy.
Acta neurochirurgica 2000;142(1):1-15.
1999: Ian Piper; A Spiegelberg; Ian R Whittle; David F Signorini; L Mascia
A comparative study of the Spiegelberg compliance device with a manual volume-injection method: a clinical evaluation in patients with hydrocephalus.
British journal of neurosurgery 1999;13(6):581-6.
1999: Helen S Bell; SB Wharton; helen Leaver; Ian R Whittle
Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels.
Journal of neurosurgery 1999;91(6):989-96.
1999: Ian R Whittle; G R Dow; G Alistair Lammie; Joanna Wardlaw
Dsyembryoplastic neuroepithelial tumour with discrete bilateral multifocality: further evidence for a germinal origin.
British journal of neurosurgery 1999;13(5):508-11.
1999: M B Delgado; J R Anderson; Ian R Whittle; SB Wharton
Expression of Bcl-2 and Bax in oligodendrogliomas and their relationship to apoptosis.
Neuropathology and applied neurobiology 1999;25(5):400-7.
1999: Ian R Whittle; GP Malcolm; D I Jodrell; M Reid
Platinum distribution in malignant glioma following intraoperative intravenous infusion of carboplatin.
British journal of neurosurgery 1999;13(2):132-7.
1999: helen Leaver; JR Williams; James W Ironside; Eric P Miller; A Gregor; B H Su; Robin J Prescott; Ian R Whittle
Dynamics of reactive oxygen intermediate production in human glioma: n-6 essential fatty acid effects.
European journal of clinical investigation 1999;29(3):220-31.
1999: AM Pringle; R Taylor; Ian R Whittle
Anxiety and depression in patients with an intracranial neoplasm before and after tumour surgery.
British journal of neurosurgery 1999;13(1):46-51.
1998: helen Leaver; Ian R Whittle; SB Wharton; James W Ironside
Apoptosis in human primary brain tumours.
British journal of neurosurgery 1998;12(6):539-46.
1998: AM Thomson; R Taylor; Ian R Whittle
Assessment of communication impairment and the effects of resective surgery in solitary, right-sided supratentorial intracranial tumours: a prospective study.
British journal of neurosurgery 1998;12(5):423-9.
1998: J Hooper; R Taylor; B Pentland; Ian R Whittle
Rater reliability of Fahn's tremor rating scale in patients with multiple sclerosis.
Archives of physical medicine and rehabilitation 1998;79(9):1076-9.
1998: Ian R Whittle; Michael A Glasby; A Lammie; H Bell; U Ungerstedt
Neuropathological findings after intracerebral implantation of microdialysis catheters.
Neuroreport 1998;9(12):2821-5.
1998: Gopal R Swaroop; GP Malcolm; Paul A T Kelly; Isobel M Ritchie; Ian R Whittle
Effects of nitric oxide modulation on tumour blood flow and microvascular permeability in C6 glioma.
Neuroreport 1998;9(11):2577-81.
1998: Gopal R Swaroop; Ian R Whittle
Pineal apoplexy: an occurrence with no diagnostic clinicopathological features.
British journal of neurosurgery 1998;12(3):274-6.
1998: AZ Latif; David F Signorini; Anna Gregor; Robert Grant; James W Ironside; Ian R Whittle
Application of the MRC brain tumour prognostic index to patients with malignant glioma not managed in randomised control trial.
Journal of neurology, neurosurgery, and psychiatry 1998;64(6):747-50.
1998: JR Williams; helen Leaver; James W Ironside; A Gregor; E Miller; Ian R Whittle
Kinetics of reactive oxygen intermediate formation and apoptosis in human glioma and glioma C6 cell line: effects of radiation and n-6 essential fatty acids.
Biochemical Society transactions 1998;26(2):S141.
1998: J M Wardlow; G Alistair Lammie; Ian R Whittle
A brain haemorrhage?
Lancet 1998;351(9108):1028.
1998: Ian R Whittle; AM Pringle; R Taylor
Effects of resective surgery for left-sided intracranial tumours on language function: a prospective study.
Lancet 1998;351(9108):1014-8.
1998: AZ Latif; David F Signorini; Anna Gregor; Ian R Whittle
The costs of managing patients with malignant glioma at a neuro-oncology clinic.
British journal of neurosurgery 1998;12(2):118-22.
1998: H Bell; WL Kimber; M Li; Ian R Whittle
Liposomal transfection efficiency and toxicity on glioma cell lines: in vitro and in vivo studies.
Neuroreport 1998;9(5):793-8.
1998: JR Williams; helen Leaver; James W Ironside; Eric P Miller; Ian R Whittle; A Gregor
Apoptosis in human primary brain tumours: actions of arachidonic acid.
Prostaglandins, leukotrienes, and essential fatty acids 1998;58(3):193-200.
1998: AZ Latif; David F Signorini; Ian R Whittle
Treatment by a specialist surgical neuro-oncologist does not provide any survival advantage for patients with a malignant glioma.
British journal of neurosurgery 1998;12(1):29-32.
1998: Ian R Whittle; DC Macarthur; G P Malcolm; M Li; K Washington; J W Ironside
Can experimental models of rodent implantation glioma be improved? A study of pure and mixed glioma cell line tumours.
Journal of neuro-oncology 1998;36(3):231-42.
1998: GP Malcolm; D I Jodrell; AJ MacLellan; Gopal R Swaroop; Paul A T Kelly; Ian R Whittle
Effects of nitric oxide manipulation on the disposition of platinum in an experimental glioma model.
Neuroreport 1998;9(2):181-5.
1998: Ian R Whittle; J Hooper; B Pentland
Thalamic deep-brain stimulation for movement disorders due to multiple sclerosis.
Lancet 1998;351(9096):109-10.
1997: helen Leaver; JR Williams; Stewart R Craig; A Gregor; James W Ironside; Ian R Whittle; B H Su; PL Yap
Network analysis of arachidonic acid pathophysiology in human phagocytes and primary brain tumors.
Annals of the New York Academy of Sciences 1997;832():200-14.
1997: Gopal R Swaroop; Ian R Whittle
Exophytic pontine glioblastoma mimicking acoustic neuroma.
Journal of neurosurgical sciences 1997;41(4):409-11.
1997: AM Thomson; R Taylor; D Fraser; Ian R Whittle
Stereotactic biopsy of nonpolar tumors in the dominant hemisphere: a prospective study of effects on language functions.
Journal of neurosurgery 1997;86(6):923-6.
1997: Ioannis P Fouyas; Paul A T Kelly; Isobel M Ritchie; Ian R Whittle
Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats.
British journal of pharmacology 1997;121(1):49-56.
1997: Ian R Whittle; H M Marston
Progressive focal neurological dysfunction following experimental implantation glioma.
Neuroreport 1997;8(5):1149-53.
1997: AM Thomson; R Taylor; D Fraser; Ian R Whittle
The utility of the Right Hemisphere Language Battery in patients with brain tumours.
European journal of disorders of communication : the journal of the College of Speech and Language Therapists, London 1997;32(3 Spec No):325-32.
1997: Ian R Whittle; WL Kimber; M Li; Helen S Bell; James W Ironside
Glioma cells transduced with selection transgenes may not form gliomas in vivo and can also inhibit glioma formation by admixed wild glioma cell lines.
Acta neurochirurgica. Supplement 1997;68():139-43.
1996: Ian R Whittle; R Viswanathan
Acute intraoperative brain herniation during elective neurosurgery: pathophysiology and management considerations.
Journal of neurology, neurosurgery, and psychiatry 1996;61(6):584-90.
1996: Ian R Whittle
Therapeutic approaches to primary and secondary brain tumours.
Neuropathology and applied neurobiology 1996;22(5):424-9.
1996: M G O'Sullivan; Robin J Sellar; P F Statham; Ian R Whittle
Management of poor grade patients after subarachnoid haemorrhage: the importance of neuroradiological findings on clinical outcome.
British journal of neurosurgery 1996;10(5):445-52.
1996: Ian R Whittle; Mark Broadbent; A Boyd; S Lahiri; A Robbins; R Klutting; L Henderson; J McMillan
Public perceptions of brain tumours in Scotland: the need for access to appropriate information.
Scottish medical journal 1996;41(3):87-9.
1996: I P Fouyas; Paul A T Kelly; Isobel M Ritchie; Ian R Whittle
Cerebrovascular responsiveness to NG-nitro-L-arginine methyl ester in spontaneously diabetic rats.
British journal of pharmacology 1996;118(2):243-8.
1996: G P Malcolm; R Gibson; J W Ironside; Ian R Whittle
Microsurgical excision of a pontomedullary epidermoid cyst with prepontine extension: case report.
Neurosurgery 1996;38(3):579-83; discussion 582-3.
1996: Ian R Whittle; F Collins; P A Kelly; I Ritchie; J W Ironside
Nitric oxide synthase is expressed in experimental malignant glioma and influences tumour blood flow.
Acta neurochirurgica 1996;138(7):870-5; discussion 875-6.
1996: A Beaumont; M Clarke; Ian R Whittle
The effects of malignant glioma on the EEG and seizure thresholds: an experimental study.
Acta neurochirurgica 1996;138(4):370-81.
1995: Ian R Whittle; J L Jenkinson
CT-guided stereotactic antero-medial pulvinotomy and centromedian-parafascicular thalamotomy for intractable malignant pain.
British journal of neurosurgery 1995;9(2):195-200.
1995: Michael A Glasby; R. Eddie Clutton; S J Drew; M G O'Sullivan; Ian R Whittle
Repair of the facial nerve in the cerebellopontine angle using freeze-thawed skeletal muscle autografts. An experimental surgical study in the sheep.
Acta neurochirurgica 1995;136(3-4):151-9.
1995: Ian R Whittle; A Beaumont
Seizures in patients with supratentorial oligodendroglial tumours. Clinicopathological features and management considerations.
Acta neurochirurgica 1995;135(1-2):19-24.
1995: Ian R Whittle; Lewis John Haddow
CT guided thalamotomy for movement disorders in multiple sclerosis: problems and paradoxes.
Acta neurochirurgica. Supplement 1995;64():13-6.
1994: C E Counsell; R Taylor; Ian R Whittle
Focal necrotising herpes simplex encephalitis: a report of two cases with good clinical and neuropsychological outcomes.
Journal of neurology, neurosurgery, and psychiatry 1994;57(9):1115-7.
1994: R Viswanathan; D C MacArthur; Ian R Whittle
Nail gun injury to the brain: an unusual case of suicide.
Scottish medical journal 1994;39(3):83.
1994: Ian R Whittle; M O'Sullivan; James W Ironside; Robin J Sellar
An experimental study to evaluate the accuracy of diencephalic and pallidal target localization using the Brown-Roberts-Wells stereotactic system and unreformatted axial GE8800 CT scanning.
British journal of neurosurgery 1994;8(1):63-72.
1994: M G O'Sullivan; N Dorward; Ian R Whittle; A J Steers; J D Miller
Management and long-term outcome following subarachnoid haemorrhage and intracranial aneurysm surgery in elderly patients: an audit of 199 consecutive cases.
British journal of neurosurgery 1994;8(1):23-30.
1994: R Viswanathan; James W Ironside; Jeanne E Bell; R P Brettle; Ian R Whittle
Stereotaxic brain biopsy in AIDS patients: does it contribute to patient management?
British journal of neurosurgery 1994;8(3):307-11.
1994: S J Cole; D E Fraser; Ian R Whittle
Rapid resolution following chemotherapy of Broca's dysphasia due to recurrent anaplastic astrocytoma.
British journal of neurosurgery 1994;8(2):205-8.
1994: Ian R Whittle; M O'Sullivan; Robin J Sellar; James W Ironside
Teaching image-guided stereotactic methodology and functional neuroanatomy of the thalamus and pallidum: a simple ex vivo technique.
British journal of neurosurgery 1994;8(5):579-83.
1994: Robert Grant; J Slattery; Anna Gregor; Ian R Whittle
Recording neurological impairment in clinical trials of glioma.
Journal of neuro-oncology 1994;19(1):37-49.
1994: M G O'Sullivan; M Whyman; J W Steers; Ian R Whittle; J D Miller
Acute subdural haematoma secondary to ruptured intracranial aneurysm: diagnosis and management.
British journal of neurosurgery 1994;8(4):439-45.
1993: Ian Piper; K H Chan; Ian R Whittle; J D Miller
An experimental study of cerebrovascular resistance, pressure transmission, and craniospinal compliance.
Neurosurgery 1993;32(5):805-15; discussion 815-6.
1993: Ian R Whittle; J W Ironside; Ian Piper; J D Miller
Neuropathological and neurophysiological effects of interstitial white matter autologous and non-autologous protein containing solutions: further evidence for a glioma derived permeability factor.
Acta neurochirurgica 1993;120(3-4):164-74.
1993: N L Dorward; R A Hawkins; Ian R Whittle
Epidermal growth factor receptor activity and clinical outcome in glioblastoma and meningioma.
British journal of neurosurgery 1993;7(2):197-9.
1993: Ian R Whittle; M G O'Sullivan; James W Ironside; Robin J Sellar
Accuracy of ventrolateral thalamic nucleus localization using unreformatted CT scans and the B-R-W system. Experimental studies and clinical findings during functional neurosurgery.
Acta neurochirurgica. Supplementum 1993;58():61-4.
1992: M E Chapman; Robin J Sellar; Ian R Whittle
Pyocephalus: a valuable CT finding in cerebral abscess.
Clinical radiology 1992;45(3):195-7.
1992: Ian R Whittle; Ian Piper; J D Miller
The role of bradykinin in the etiology of vasogenic brain edema and perilesional brain dysfunction.
Acta neurochirurgica 1992;115(1-2):53-9.
1992: Ian R Whittle; Robin J Sellar; James W Ironside
Epileptogenic anaplastic astrocytoma imaged only by T2-weighted magnetic resonance studies: clinical and surgical implications.
British journal of neurosurgery 1992;6(6):537-42.
1992: Ian R Whittle
Anterior lateral ventricular subependymal giant cell astrocytomas. Microsurgical aspects of two cases.
Acta neurochirurgica 1992;118(3-4):176-80.
1992: Ian R Whittle; M Clarke; A Gregori; Ian Piper; J D Miller
Interstitial white matter brain oedema does not alter the electroencephalogram.
British journal of neurosurgery 1992;6(5):433-7.
1992: Anna Gregor; R Rampling; M Aapro; P Malmström; Ian R Whittle; R Rye; M Stewart; R Sellar; B Demierre; J W Ironside
Phase II study of tauromustine in malignant glioma.
European journal of cancer (Oxford, England : 1990) 1992;28A(12):1959-62.
1991: Ian R Whittle; S W Denholm; K Elshunnar
CT-guided stereotactic neurosurgery using the Brown-Roberts-Wells system: experience with 125 procedures.
The Australian and New Zealand journal of surgery 1991;61(12):919-28.
1991: Ian R Whittle; S W Denholm; A Gregor
Management of patients aged over 60 years with supratentorial glioma: lessons from an audit.
Surgical neurology 1991;36(2):106-11.
1991: Ian R Whittle; Ian Piper; J D Miller
The contribution of arachidonic acid to the aetiology and pathophysiology of focal brain oedema; studies using an infusion oedema model.
Acta neurochirurgica 1991;113(1-2):57-68.
1991: Ian R Whittle; D E Fraser
Resolution of fluent dysphasia following excision of metastatic carcinoma from the arcuate fasciculus.
British journal of neurosurgery 1991;5(6):647-9.
1990: Ian R Whittle; J S MacPherson; J D Miller; John F Smyth
The disposition of TCNU (tauromustine) in human malignant glioma: pharmacokinetic studies and clinical implications.
Journal of neurosurgery 1990;72(5):721-5.
1990: K S Elshunnar; Ian R Whittle
Familial intracranial aneurysms: report of five families.
British journal of neurosurgery 1990;4(3):181-6.
1990: Ian R Whittle; J D Miller
A rodent model of infusion brain edema: methodology and pathophysiological effects of saline and protein infusions.
Acta neurochirurgica 1990;105(3-4):158-68.
1990: H I Sabin; Ian R Whittle
Stereotactic craniotomy and intraoperative lesion localisation using the Brown-Robert-Wells frame. Technical note.
Acta neurochirurgica 1990;102(3-4):137-40.
1990: Ian R Whittle; Ian Piper; J D Miller
The contribution of secondary mediators to the etiology and pathophysiology of brain oedema: studies using a feline infusion oedema model.
Acta neurochirurgica. Supplementum 1990;51():71-3.
1989: L J Abernethy; Ian R Whittle; Robin J Sellar
Leptomeningeal cyst of the orbit presenting with pulsatile exophthalmos.
Clinical radiology 1989;40(5):531-2.
1989: Ian R Whittle; A Gordon; B K Misra; J F Shaw; A J Steers
Pleomorphic xanthoastrocytoma. Report of four cases.
Journal of neurosurgery 1989;70(3):463-8.
1989: R D Strachan; Ian R Whittle; J D Miller
Hypothermia and severe head injury.
Brain injury : [BI] 1989;3(1):51-5.
1989: P D Hardman; J Bell; Ian R Whittle; Anna Gregor
Familial glioma: a report of glioblastoma in identical twins and oligo-astrocytoma in siblings.
British journal of neurosurgery 1989;3(6):709-15.
1989: Ian R Whittle
Oncogenes and neuro-oncology.
British journal of neurosurgery 1989;3(1):3-11.
1988: B K Misra; Ian R Whittle; A J Steers; Robin J Sellar
De novo saccular aneurysms.
Neurosurgery 1988;23(1):10-5.
1988: Ian R Whittle; R A Hawkins; E Killen; J D Miller
Epidermal growth factor binding in intracranial neoplasms: preliminary biochemical and clinicopathological findings.
British journal of neurosurgery 1988;2(2):211-5.
1988: J C Sutcliffe; J D Miller; Ian R Whittle; A J Steers
Gas gangrene occurring soon after compound depressed skull fracture.
Acta neurochirurgica 1988;95(1-2):53-6.
1987: Ian R Whittle; J S Macpherson; J Smyth; J D Miller
Experimental cerebral and plasma pharmacokinetic studies of TCNU: implications for brain tumour chemotherapy.
British journal of neurosurgery 1987;1(3):365-8.