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Wolfgang Wick

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Alexander Radbruch; Matthias Roethke; Felix Sahm; Heinz-Peter Schlemmer; Markus Weiler; Wolfgang Wick; Benedikt Wiestler; Philipp Bäumer; Sabine Heiland; Linda Kramp; Kira Lutz; Martin Bendszus
Differentiation of glioblastoma and primary CNS lymphomas using susceptibility weighted imaging.
C Seidel; M Simon; M Tatagiba; Michael Weller; Oliver Heese; B Hentschel; A Kowoll; Dietmar Krex; T Reithmeier; O Schnell; Wolfgang Wick
A comprehensive analysis of vascular complications in 3,889 glioma patients from the German Glioma Network.
Katharina Seystahl; Michael Weller; Caroline Happold; Thomas Hundsberger; Wolfgang Wick; Benedikt Wiestler; Antje Wick
Bevacizumab alone or in combination with irinotecan in recurrent WHO grade II and grade III gliomas.

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2013: Alexander Radbruch; Matthias Roethke; Felix Sahm; Heinz-Peter Schlemmer; Markus Weiler; Wolfgang Wick; Benedikt Wiestler; Philipp Bäumer; Sabine Heiland; Linda Kramp; Kira Lutz; Martin Bendszus
Differentiation of glioblastoma and primary CNS lymphomas using susceptibility weighted imaging.
European journal of radiology 2013;82(3):552-6.
2013: C Seidel; M Simon; M Tatagiba; Michael Weller; Oliver Heese; B Hentschel; A Kowoll; Dietmar Krex; T Reithmeier; O Schnell; Wolfgang Wick
A comprehensive analysis of vascular complications in 3,889 glioma patients from the German Glioma Network.
Journal of neurology 2013;260(3):847-55.
2013: Katharina Seystahl; Michael Weller; Caroline Happold; Thomas Hundsberger; Wolfgang Wick; Benedikt Wiestler; Antje Wick
Bevacizumab alone or in combination with irinotecan in recurrent WHO grade II and grade III gliomas.
European neurology 2013;69(2):95-101.
2013: Michael Weller; Timothy Cloughesy; James R Perry; Wolfgang Wick
Standards of care for treatment of recurrent glioblastoma--are we there yet?
Neuro-oncology 2013;15(1):4-27.
2013: Stephanie E Combs; Lutz Edler; Renate Rausch; Thomas Welzel; Wolfgang Wick; Jürgen Debus
Generation and validation of a prognostic score to predict outcome after re-irradiation of recurrent glioma.
Acta oncologica (Stockholm, Sweden) 2013;52(1):147-52.
2012: Markus Weiler; Wolfgang Wick
Molecular predictors of outcome in low-grade glioma.
Current opinion in neurology 2012;25(6):767-73.
2012: Michael Weller; Wolfgang Wick; Monika E Hegi; Marc Sanson; Roger Stupp; Joerg C Tonn; Martin van den Bent; Guido Reifenberger
Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice.
Neuro-oncology 2012;14 Suppl 4():iv100-8.
2012: Michael Weller; Roger Stupp; Wolfgang Wick
Epilepsy meets cancer: when, why, and what to do about it?
The lancet oncology 2012;13(9):e375-82.
2012: Rezvan Ahmadi; Natalia Becker; David Capper; Arne Christians; Christine Dictus; Christel Herold-Mende; Katarina Hohlen; Martin Misch; Florian Stockhammer; Andreas Unterberg; Andreas von Deimling; Wolfgang Wick; Christian Hartmann
No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas.
Journal of neuro-oncology 2012;109(1):15-22.
2012: Wolfgang Wick; Christian Braun; Stephanie E Combs; Jörg Felsberg; Ralf Ketter; Regine Mayer-Steinacker; Christoph Meisner; Jürgen Meixensberger; Guido Nikkhah; Kirsten Papsdorf; Michael Platten; Guido Reifenberger; Michael Sabel; Matthias Simon; Joachim P Steinbach; Ghazaleh Tabatabai; Jan Vesper; Michael Weller
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
The lancet oncology 2012;13(7):707-15.
2012: Leonie Jestaedt; Dieter Lemke; Philipp-Niclas Pfenning; Markus Weiler; Wolfgang Wick; Sabine Heiland; Martin Bendszus
Gadofluorine M enhanced MRI in experimental glioma: superior and persistent intracellular tumor enhancement compared with conventional MRI.
Journal of magnetic resonance imaging : JMRI 2012;35(3):551-60.
2012: Alexander Radbruch; Wolfgang Wick; Benedikt Wiestler; Philipp Bäumer; Sabine Heiland; Kira Lutz; Martin Bendszus
Relevance of T2 signal changes in the assessment of progression of glioblastoma according to the Response Assessment in Neurooncology criteria.
Neuro-oncology 2012;14(2):222-9.
2011: Michael Weller; Michael Platten; Patrick Roth; Wolfgang Wick
Geriatric neuro-oncology: from mythology to biology.
Current opinion in neurology 2011;24(6):599-604.
2011: Stefan Rieken; Thomas Welzel; Wolfgang Wick; Olaf Witt; Jürgen Debus; Daniel Habermehl; Andreas E Kulozik; Katja Lindel; Angela Mohr; Stephanie E Combs
Outcome and prognostic factors of radiation therapy for medulloblastoma.
International journal of radiation oncology, biology, physics 2011;81(3):e7-e13.
2011: Christiane A. Opitz; Martina Ott; Gilles J Guillemin; Leonie Jestaedt; Manfred Jugold; Irina Lehmann; Ulrike M Litzenburger; Christian Lutz; Christine L Miller; Bernhard Radlwimmer; Felix Sahm; Dieter Schrenk; Theresa Schumacher; Isabel Tritschler; Saskia Trump; Andreas von Deimling; Michael Weller; Wolfgang Wick; Michael Platten
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.
Nature 2011;478(7368):197-203.
2011: Anne Hertenstein; Ulrike Litzenburger; Christiane A. Opitz; Theresa Schumacher; Tito Serafini; Wolfgang Wick; Christine S Falk; Michael Platten
Suppression of human CD4+ T cell activation by 3,4-dimethoxycinnamonyl-anthranilic acid (tranilast) is mediated by CXCL9 and CXCL10.
Biochemical pharmacology 2011;82(6):632-41.
2011: Wolfgang Wick
Anaplastic gliomas: an emerging entity.
European journal of cancer (Oxford, England : 1990) 2011;47 Suppl 3():S357-8.
2011: Michael Weller; Wolfgang Wick; Andreas von Deimling
Isocitrate dehydrogenase mutations: a challenge to traditional views on the genesis and malignant progression of gliomas.
Glia 2011;59(8):1200-4.
2011: Silvia Hofer; Katarzyna Elandt; Richard Greil; Andreas F Hottinger; Urs Huber; Dieter Lemke; Christine Marosi; Adrian F Ochsenbein; Josef Pichler; Ulrich Roelcke; Patrik Weder; Thilo Zander; Wolfgang Wick; Michael Weller
Clinical outcome with bevacizumab in patients with recurrent high-grade glioma treated outside clinical trials.
Acta oncologica (Stockholm, Sweden) 2011;50(5):630-5.
2011: Wolfgang Wick; Michael Weller
Trabedersen to target transforming growth factor-beta: when the journey is not the reward, in reference to Bogdahn et al. (Neuro-Oncology 2011;13:132-142).
Neuro-oncology 2011;13(5):559-60; author reply 561-2.
2011: Günter Eisele; Patrick Roth; Kathy Hasenbach; Steffen Aulwurm; Fabian Wolpert; Ghazaleh Tabatabai; Wolfgang Wick; Michael Weller
APO010, a synthetic hexameric CD95 ligand, induces human glioma cell death in vitro and in vivo.
Neuro-oncology 2011;13(2):155-64.
2011: Stephanie E Combs; Jürgen Debus; Stefan Rieken; Andreas von Deimling; Wolfgang Wick; Amir Abdollahi; Christian Hartmann
Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back?
Radiation oncology (London, England) 2011;6():115.
2011: Christiane A. Opitz; Ulrike M Litzenburger; Uta Opitz; Felix Sahm; Katharina Ochs; Christian Lutz; Wolfgang Wick; Michael Platten
The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells.
PloS one 2011;6(5):e19823.
2010: Christian Hartmann; Bettina Hentschel; Wolfgang Wick; David Capper; Jörg Felsberg; Matthias Simon; Manfred Westphal; Gabriele Schackert; Richard Meyermann; Torsten Pietsch; Guido Reifenberger; Michael Weller; Markus Loeffler; Andreas von Deimling
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas.
Acta neuropathologica 2010;120(6):707-18.
2010: Patrick Roth; Wolfgang Wick; Michael Weller
Steroids in neurooncology: actions, indications, side-effects.
Current opinion in neurology 2010;23(6):597-602.
2010: Ghazaleh Tabatabai; Roger Stupp; Martin J van den Bent; Monika E Hegi; Jörg C Tonn; Wolfgang Wick; Michael Weller
Molecular diagnostics of gliomas: the clinical perspective.
Acta neuropathologica 2010;120(5):585-92.
2010: Michael Weller; Wolfgang Wick; Monika E Hegi; Roger Stupp; Ghazaleh Tabatabai
Should biomarkers be used to design personalized medicine for the treatment of glioblastoma?
Future oncology (London, England) 2010;6(9):1407-14.
2010: Benjamin Berger; David Capper; Dieter Lemke; Philipp-Niclas Pfenning; Michael Platten; Michael Weller; Andreas von Deimling; Wolfgang Wick; Markus Weiler
Defective p53 antiangiogenic signaling in glioblastoma.
Neuro-oncology 2010;12(9):894-907.
2010: Patrick Roth; Markus Junker; Isabel Tritschler; Michel Mittelbronn; Yvonne Dombrowski; Samuel N Breit; Ghazaleh Tabatabai; Wolfgang Wick; Michael Weller; Jörg Wischhusen
GDF-15 contributes to proliferation and immune escape of malignant gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(15):3851-9.
2010: Markus Weiler; Christian Hartmann; Dorothee Wiewrodt; Ulrich Herrlinger; Thierry Gorlia; Oliver Bähr; Richard Meyermann; D D; Marcos Tatagiba; Andreas von Deimling; Michael Weller; Wolfgang Wick
Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.
International journal of radiation oncology, biology, physics 2010;77(3):670-6.
2010: Ghazaleh Tabatabai; Kathy Hasenbach; Caroline Herrmann; Gabriele Maurer; Robert Möhle; Patrizia Marini; Manuel Grez; Wolfgang Wick; Michael Weller
Glioma tropism of lentivirally transduced hematopoietic progenitor cells.
International journal of oncology 2010;36(6):1409-17.
2010: Doris Brötz; Evelin Maschke; Susanne Burkard; Corinna Engel; Constantin Mänz; Ulrike Ernemann; Wolfgang Wick; Michael Weller
Is there a role for benzodiazepines in the management of lumbar disc prolapse with acute sciatica?
Pain 2010;149(3):470-5.
2010: Tobias V Lanz; Christiane A. Opitz; Peggy P Ho; Ankur Agrawal; Christian Lutz; Michael Weller; Andrew L Mellor; Lawrence Steinman; Wolfgang Wick; Michael Platten
Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1).
Stem cells and development 2010;19(5):657-68.
2010: Wolfgang Wick; Vinay K Puduvalli; Marc C Chamberlain; Martin J van den Bent; Antoine F Carpentier; Lawrence M Cher; Warren Mason; Michael Weller; Shengyan Hong; Luna Musib; Astra M Liepa; Donald E Thornton; Howard A Fine
Phase III study of enzastaurin compared with lomustine in the treatment of recurrent intracranial glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(7):1168-74.
2010: Antje Wick; N Schäfer; N Dörner; D Schemmer; Michael Platten; M Bendszus; Wolfgang Wick
Arterial hypertension and bevacizumab treatment in glioblastoma: no correlation with clinical outcome.
Journal of neuro-oncology 2010;97(1):157-8.
2010: Stephanie E Combs; Lutz Edler; Iris Burkholder; Stefan Rieken; Daniel Habermehl; Oliver Jäkel; Thomas Haberer; Andreas Unterberg; Wolfgang Wick; Jürgen Debus; Renate Haselmann
Treatment of patients with atypical meningiomas Simpson grade 4 and 5 with a carbon ion boost in combination with postoperative photon radiotherapy: the MARCIE trial.
BMC cancer 2010;10():615.
2010: Stephanie E Combs; Iris Burkholder; Lutz Edler; Stefan Rieken; Daniel Habermehl; Oliver Jäkel; Thomas Haberer; Renate Haselmann; Andreas Unterberg; Wolfgang Wick; Jürgen Debus
Randomised phase I/II study to evaluate carbon ion radiotherapy versus fractionated stereotactic radiotherapy in patients with recurrent or progressive gliomas: the CINDERELLA trial.
BMC cancer 2010;10():533.
2010: Stephanie E Combs; Meinhard Kieser; Stefan Rieken; Daniel Habermehl; Oliver Jäkel; Thomas Haberer; Anna Nikoghosyan; Renate Haselmann; Andreas Unterberg; Wolfgang Wick; Jürgen Debus
Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial.
BMC cancer 2010;10():478.
2010: Stefan Rieken; Timo Gaiser; Angela Mohr; Thomas Welzel; Olaf Witt; Andreas E Kulozik; Wolfgang Wick; Jürgen Debus; Stephanie E Combs
Outcome and prognostic factors of desmoplastic medulloblastoma treated within a multidisciplinary treatment concept.
BMC cancer 2010;10():450.
2010: Michael Weller; Roger Stupp; Guido Reifenberger; Alba A Brandes; Martin J van den Bent; Wolfgang Wick; Monika E Hegi
MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
Nature reviews. Neurology 2010;6(1):39-51.
2009: Wolfgang Wick; Christian Hartmann; Corinna Engel; Mandy Stoffels; Jörg Felsberg; Florian Stockhammer; Michael C Sabel; Susanne Koeppen; Ralf Ketter; Richard Meyermann; Marion Rapp; Christoph Meisner; Rolf-Dieter Kortmann; Torsten Pietsch; Otmar D Wiestler; Ulrike Ernemann; D D; Guido Reifenberger; Andreas von Deimling; Michael Weller
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(35):5874-80.
2009: Wolfgang Wick; Michael Weller
Classification and management of anaplastic gliomas.
Current opinion in neurology 2009;22(6):650-6.
2009: Gabriele D Maurer; Isabel Tritschler; Barbara Adams; Ghazaleh Tabatabai; Wolfgang Wick; Roger Stupp; Michael Weller
Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.
Neuro-oncology 2009;11(6):747-56.
2009: Christian Hartmann; Jochen Meyer; Jörg Balss; David Capper; Wolf Mueller; Arne Christians; Jörg Felsberg; Marietta Wolter; Christian Mawrin; Wolfgang Wick; Michael Weller; Christel Herold-Mende; Andreas Unterberg; Judith W M Jeuken; Peter Wesseling; Guido Reifenberger; Andreas von Deimling
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.
Acta neuropathologica 2009;118(4):469-74.
2009: Isabel Tritschler; Dorothee Gramatzki; David Capper; Michel Mittelbronn; Richard Meyermann; Juha Saharinen; Wolfgang Wick; Jorma Keski-Oja; Michael Weller
Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells.
International journal of cancer. Journal international du cancer 2009;125(3):530-40.
2009: D Gramatzki; G Pantazis; Jens Schittenhelm; Ghazaleh Tabatabai; Christoph Köhle; Wolfgang Wick; Michael Schwarz; Michael Weller; I Tritschler
Aryl hydrocarbon receptor inhibition downregulates the TGF-beta/Smad pathway in human glioblastoma cells.
Oncogene 2009;28(28):2593-605.
2009: Antje Wick; Christina Pascher; Wolfgang Wick; Tanja Jauch; Michael Weller; Ulrich Bogdahn; Peter Hau
Rechallenge with temozolomide in patients with recurrent gliomas.
Journal of neurology 2009;256(5):734-41.
2009: Christiane A. Opitz; Ulrike M Litzenburger; Christian Lutz; Tobias V Lanz; Isabel Tritschler; Alexandra Köppel; Eva Tolosa; Maik Hoberg; Jan Anderl; Wilhelm K Aicher; Michael Weller; Wolfgang Wick; Michael Platten
Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R.
Stem cells (Dayton, Ohio) 2009;27(4):909-19.
2009: Caroline Happold; Patrick Roth; Wolfgang Wick; Joachim P Steinbach; Michael Linnebank; Michael Weller; Günter Eisele
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
Journal of neuro-oncology 2009;92(1):45-8.
2009: Wolfgang Wick; Michael Weller
Adjuvant therapy.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2009;171():141-53.
2008: Caroline Happold; Ulrike Ernemann; Patrick Roth; Wolfgang Wick; Michael Weller; Friederike Schmidt
Anticoagulation for radiation-induced neurotoxicity revisited.
Journal of neuro-oncology 2008;90(3):357-62.
2008: Johannes Rieger; Dieter Lemke; Gabriele Maurer; Markus Weiler; Brigitte Frank; Ghazaleh Tabatabai; Michael Weller; Wolfgang Wick
Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL.
Journal of neurochemistry 2008;106(6):2436-48.
2008: Doris Broetz; Ulrich Hahn; Evelin Maschke; Wolfgang Wick; Wilhelm Kueker; Michael Weller
Lumbar disk prolapse: response to mechanical physiotherapy in the absence of changes in magnetic resonance imaging. Report of 11 cases.
NeuroRehabilitation 2008;23(3):289-94.
2007: Christiane A. Opitz; Wolfgang Wick; L Steinman; Michael Platten
Tryptophan degradation in autoimmune diseases.
Cellular and molecular life sciences : CMLS 2007;64(19-20):2542-63.
2007: Michael Platten; Christiane A. Opitz; P Kohlhof; U Hegenbart; Anthony Ho; Wolfgang Wick
Painful neuropathy due to intraneural leukemic spread in a patient with acute myeloid leukemia.
Neurology 2007;69(7):707.
2007: Antje Wick; Jörg Felsberg; Joachim P Steinbach; Ulrich Herrlinger; Michael Platten; Britta Blaschke; Richard Meyermann; Guido Reifenberger; Michael Weller; Wolfgang Wick
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(22):3357-61.
2007: Thomas-Toan Tran; Martin Uhl; Jing Ying Ma; Lisa Janssen; Venkataraman Sriram; Steffen Aulwurm; Irene Kerr; Andrew Lam; Heather K Webb; Ann M Kapoun; Darin E Kizer; Glenn McEnroe; Barry Hart; Jonathan Axon; Alison Murphy; Sarvajit Chakravarty; Sundeep Dugar; Protter Andrew; Linda S Higgins; Wolfgang Wick; Michael Weller; Darren H Wong
Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.
Neuro-oncology 2007;9(3):259-70.
2007: Michel Mittelbronn; David Capper; B Bunz; Klaus Dietz; Benjamin Goeppert; R Ajaaj; Ghazaleh Tabatabai; Florian Stubenvoll; Holger Schlaszus; Axel S Merseburger; Ralf Becker; Dirk Freudenstein; Wolfgang Wick; Michael Weller; Richard Meyermann; Perikles Simon
De novo erythropoietin receptor (EPO-R) expression in human neoplastic glial cells decreases with grade of malignancy but is favourably associated with patient survival.
Neuropathology and applied neurobiology 2007;33(3):299-307.
2007: Henning Vollmann; Sarah Wölfel; Petra Ohneseit; Elke Stransky; Reinhard Vonthein; Wolfgang Wick; Richard Meyermann; Perikles Simon
Differential expression of egr1 and activation of microglia following irradiation in the rat brain.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2007;183(5):248-55.
2007: Patrick Roth; Michel Mittelbronn; Wolfgang Wick; Richard Meyermann; Marcos Tatagiba; Michael Weller
Malignant glioma cells counteract antitumor immune responses through expression of lectin-like transcript-1.
Cancer research 2007;67(8):3540-4.
2007: Isabel Burghardt; Felix Tritschler; Christiane A. Opitz; Brigitte Frank; Michael Weller; Wolfgang Wick
Pirfenidone inhibits TGF-beta expression in malignant glioma cells.
Biochemical and biophysical research communications 2007;354(2):542-7.
2007: Ghazaleh Tabatabai; Brigitte Frank; Antje Wick; Dieter Lemke; Gabriele von Kürthy; Ulrike Obermüller; Stefan Heckl; Gunter Christ; Michael Weller; Wolfgang Wick
Synergistic antiglioma activity of radiotherapy and enzastaurin.
Annals of neurology 2007;61(2):153-61.
2007: Johannes Rieger; Brigitte Frank; Michael Weller; Wolfgang Wick
Mechanisms of resistance of human glioma cells to Apo2 ligand/TNF-related apoptosis-inducing ligand.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(1-4):23-34.
2007: Ulrike Naumann; Oliver Bähr; Hartwig Wolburg; S Altenberend; Wolfgang Wick; Peter Liston; A Ashkenazi; Michael Weller
Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice.
Gene therapy 2007;14(2):147-61.
2006: Ulrich Herrlinger; Johannes Rieger; Dorothee Koch; Simon Loeser; Britta Blaschke; Rolf-Dieter Kortmann; Joachim P Steinbach; Thomas Hundsberger; Wolfgang Wick; Richard Meyermann; Ta-Chih Tan; Clemens Sommer; D D; Guido Reifenberger; Michael Weller
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(27):4412-7.
2006: Ghazaleh Tabatabai; Brigitte Frank; Robert Möhle; Michael Weller; Wolfgang Wick
Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.
Brain : a journal of neurology 2006;129(Pt 9):2426-35.
2006: Heike Grassmé; Jianmin Jin; Barbara Wilker; Gabriele von Kürthy; Wolfgang Wick; Michael Weller; Tarik Möröy; Erich Gulbins
Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1.
Cellular microbiology 2006;8(7):1096-105.
2006: Markus Weiler; Oliver Bähr; U Hohlweg; Ulrike Naumann; Johannes Rieger; H Huang; Ghazaleh Tabatabai; H W Krell; H Ohgaki; Michael Weller; Wolfgang Wick
BCL-xL: time-dependent dissociation between modulation of apoptosis and invasiveness in human malignant glioma cells.
Cell death and differentiation 2006;13(7):1156-69.
2006: Ilker Eyüpoglu; eric hahnen; Christian Tränkle; Nicolai E Savaskan; Florian A Siebzehnrübl; Rolf Buslei; Dieter Lemke; Wolfgang Wick; Rudolf Fahlbusch; Ingmar Blümcke
Experimental therapy of malignant gliomas using the inhibitor of histone deacetylase MS-275.
Molecular cancer therapeutics 2006;5(5):1248-55.
2006: Mirjam Hermisson; Andrea Klumpp; Wolfgang Wick; Jörg Wischhusen; Georg Nagel; Wynand Roos; Bernd Kaina; Michael Weller
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
Journal of neurochemistry 2006;96(3):766-76.
2006: Joachim P Steinbach; H-P Blaicher; Ulrich Herrlinger; Wolfgang Wick; Thomas Nägele; Richard Meyermann; M Tatagiba; D D; Johannes Dichgans; Hans-Otto Karnath; Michael Weller
Surviving glioblastoma for more than 5 years: the patient's perspective.
Neurology 2006;66(2):239-42.
2006: Wolfgang Wick; Ulrike Naumann; Michael Weller
Transforming growth factor-beta: a molecular target for the future therapy of glioblastoma.
Current pharmaceutical design 2006;12(3):341-9.
2005: Ludger Grosse-Hovest; Wolfgang Wick; Rosa Minoia; Michael Weller; Hans-Georg Rammensee; Gottfried Brem; Gundram Jung
Supraagonistic, bispecific single-chain antibody purified from the serum of cloned, transgenic cows induces T-cell-mediated killing of glioblastoma cells in vitro and in vivo.
International journal of cancer. Journal international du cancer 2005;117(6):1060-4.
2005: Michael Weller; Joachim P Steinbach; Wolfgang Wick
Temozolomide: a milestone in the pharmacotherapy of brain tumors.
Future oncology (London, England) 2005;1(6):747-54.
2005: Ghazaleh Tabatabai; Oliver Bähr; Robert Möhle; Ilker Eyüpoglu; Andreas M Boehmler; Jörg Wischhusen; Johannes Rieger; Ingmar Blümcke; Michael Weller; Wolfgang Wick
Lessons from the bone marrow: how malignant glioma cells attract adult haematopoietic progenitor cells.
Brain : a journal of neurology 2005;128(Pt 9):2200-11.
2005: Wolfgang Wick; Oliver Menn; Christoph Meisner; Joachim Steinbach; Mirjam Hermisson; Marcos Tatagiba; Michael Weller
Pharmacotherapy of epileptic seizures in glioma patients: who, when, why and how long?
Onkologie 2005;28(8-9):391-6.
2005: Ilker Eyüpoglu; eric hahnen; Rolf Buslei; Florian A Siebzehnrübl; Nicolai E Savaskan; Mike Lüders; Christian Tränkle; Wolfgang Wick; Michael Weller; Rudolf Fahlbusch; Ingmar Blümcke
Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo.
Journal of neurochemistry 2005;93(4):992-9.
2005: Martin Uhl; Markus Weiler; Wolfgang Wick; Andreas H Jacobs; Michael Weller; Ulrich Herrlinger
Migratory neural stem cells for improved thymidine kinase-based gene therapy of malignant gliomas.
Biochemical and biophysical research communications 2005;328(1):125-9.
2004: Wolfgang Wick; Christine Wild-Bode; Brigitte Frank; Michael Weller
BCL-2-induced glioma cell invasiveness depends on furin-like proteases.
Journal of neurochemistry 2004;91(6):1275-83.
2004: Antje Wick; Wolfgang Wick; Johannes Hirrlinger; Ellen Gerhardt; Ralf Dringen; Johannes Dichgans; Michael Weller; Jörg B Schulz
Chemotherapy-induced cell death in primary cerebellar granule neurons but not in astrocytes: in vitro paradigm of differential neurotoxicity.
Journal of neurochemistry 2004;91(5):1067-74.
2004: Martin Uhl; Steffen Aulwurm; Jörg Wischhusen; Markus Weiler; Jing Ying Ma; Ramona Almirez; Ruban Mangadu; Yu-Wang Liu; Michael Platten; Ulrich Herrlinger; Alison Murphy; Darren H Wong; Wolfgang Wick; Linda S Higgins; Michael Weller
SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo.
Cancer research 2004;64(21):7954-61.
2004: Manuel A Friese; Jörg Wischhusen; Wolfgang Wick; Markus Weiler; Günter Eisele; Alexander Steinle; Michael Weller
RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.
Cancer research 2004;64(20):7596-603.
2004: Wolfgang Wick; Antje Wick; Wilhelm Küker; Johannes Dichgans; Michael Weller
Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.
Journal of neuro-oncology 2004;70(1):73-5.
2004: Wolfgang Wick; Joachim P Steinbach; Wilhelm Küker; Johannes Dichgans; D D; Michael Weller
One week on/one week off: a novel active regimen of temozolomide for recurrent glioblastoma.
Neurology 2004;62(11):2113-5.
2004: Wolfgang Wick; Wilhelm Küker
Brain edema in neurooncology: radiological assessment and management.
Onkologie 2004;27(3):261-6.
2004: Ulrike Naumann; Wolfgang Wick; Rudi Beschorner; Richard Meyermann; Michael Weller
Expression and functional activity of osteoprotegerin in human malignant gliomas.
Acta neuropathologica 2004;107(1):17-22.
2003: Oliver Bähr; Johannes Rieger; Frank Duffner; Richard Meyermann; Michael Weller; Wolfgang Wick
P-glycoprotein and multidrug resistance-associated protein mediate specific patterns of multidrug resistance in malignant glioma cell lines, but not in primary glioma cells.
Brain pathology (Zurich, Switzerland) 2003;13(4):482-94.
2003: Ulrike Naumann; Friederike Schmidt; Wolfgang Wick; Brigitte Frank; Simone Weit; Bernd Gillissen; Peter Daniel; Michael Weller
Adenoviral natural born killer gene therapy for malignant glioma.
Human gene therapy 2003;14(13):1235-46.
2003: Johannes Rieger; Wolfgang Wick; Michael Weller
Human malignant glioma cells express semaphorins and their receptors, neuropilins and plexins.
Glia 2003;42(4):379-89.
2002: Ulrich Herrlinger; Jörg Felsberg; Wilhelm Küker; Antje Bornemann; Ludwig Plasswilm; Christiane B Knobbe; Herwig M Strik; Wolfgang Wick; Richard Meyermann; Johannes Dichgans; D D; Guido Reifenberger; Michael Weller
Gliomatosis cerebri: molecular pathology and clinical course.
Annals of neurology 2002;52(4):390-9.
2002: Wolfgang Wick; Mirjam Hermisson; Rolf-Dieter Kortmann; Wilhelm Küker; Frank Duffner; Johannes Dichgans; D D; Michael Weller
Neoadjuvant gemcitabine/treosulfan chemotherapy for newly diagnosed glioblastoma: a phase II study.
Journal of neuro-oncology 2002;59(2):151-5.
2002: Antje Wick; Wolfgang Wick; Johannes Waltenberger; Michael Weller; Johannes Dichgans; Jörg B Schulz
Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(15):6401-7.
2002: Wolfgang Wick; Jan Stock; Jan Seyfried; J Baumgart; Ullrich Wüllner; Michael Weller
CD95/CD95 ligand-independent potentiation of treosulfan cytotoxicity by BSO in malignant glioma cells in vitro and in vivo.
International journal of oncology 2002;21(1):213-20.
2002: Wolfgang Wick; Antje Wick; Jörg B Schulz; Johannes Dichgans; Hans P Rodemann; Michael Weller
Prevention of irradiation-induced glioma cell invasion by temozolomide involves caspase 3 activity and cleavage of focal adhesion kinase.
Cancer research 2002;62(6):1915-9.
2001: Michael Platten; Wolfgang Wick; Jörg Wischhusen; Michael Weller
N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) suppresses microglial inducible nitric oxide synthase (iNOS) expression and activity induced by interferon-gamma (IFN-gamma).
British journal of pharmacology 2001;134(6):1279-84.
2001: Ulrike Naumann; Sebastian Kügler; Hartwig Wolburg; Wolfgang Wick; Gesa Rascher; Jörg B Schulz; Emmanuel Conseiller; Mathias Bähr; Michael Weller
Chimeric tumor suppressor 1, a p53-derived chimeric tumor suppressor gene, kills p53 mutant and p53 wild-type glioma cells in synergy with irradiation and CD95 ligand.
Cancer research 2001;61(15):5833-42.
2001: Michael Platten; Christine Wild-Bode; Wolfgang Wick; J Leitlein; Johannes Dichgans; Michael Weller
N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) inhibits transforming growth factor-beta relesase and reduces migration and invasiveness of human malignant glioma cells.
International journal of cancer. Journal international du cancer 2001;93(1):53-61.
2001: Wolfgang Wick; Michael Platten; Michael Weller
Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta.
Journal of neuro-oncology 2001;53(2):177-85.
2001: Christine Wild-Bode; Michael Weller; Wolfgang Wick
Molecular determinants of glioma cell migration and invasion.
Journal of neurosurgery 2001;94(6):978-84.
2001: Wolfgang Wick; C Grimmel; Christine Wild-Bode; Michael Platten; M Arpin; Michael Weller
Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(10):3360-8.
2001: W Roth; Stefan Isenmann; M Nakamura; Michael Platten; Wolfgang Wick; P Kleihues; Mathias Bähr; H Ohgaki; A Ashkenazi; Michael Weller
Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis.
Cancer research 2001;61(6):2759-65.
2001: Christine Wild-Bode; Michael Weller; Andreas Rimner; Johannes Dichgans; Wolfgang Wick
Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma.
Cancer research 2001;61(6):2744-50.
2001: Oliver Bähr; Wolfgang Wick; Michael Weller
Modulation of MDR/MRP by wild-type and mutant p53.
The Journal of clinical investigation 2001;107(5):643-6.
2001: Michael Platten; Wolfgang Wick; Michael Weller
Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape.
Microscopy research and technique 2001;52(4):401-10.
2001: M Weller; Wolfgang Wick; Michael Platten
Role of TGF-beta in oncogenesis.
Microscopy research and technique 2001;52(4):353.
2000: F Schmidt; Wolfgang Wick; Ulrich Herrlinger; Johannes Dichgans; Michael Weller
Treosulfan chemotherapy for recurrent malignant glioma.
Journal of neuro-oncology 2000;49(3):231-4.
2000: Michael Platten; Wolfgang Wick; Christine Wild-Bode; Steffen Aulwurm; Johannes Dichgans; Michael Weller
Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via Up-regulation of alpha(V)beta(3) integrin expression.
Biochemical and biophysical research communications 2000;268(2):607-11.
1999: U Pohl; Wolfgang Wick; J Weissenberger; Joachim P Steinbach; Johannes Dichgans; Adriano Aguzzi; Michael Weller
Characterization of Tu-2449, a glioma cell line derived from a spontaneous tumor in GFAP-v-src-transgenic mice: comparison with established murine glioma cell lines.
International journal of oncology 1999;15(4):829-34.
1999: Wolfgang Wick; F B Furnari; Ulrike Naumann; Webster K Cavenee; Michael Weller
PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.
Oncogene 1999;18(27):3936-43.
1999: Wolfgang Wick; C Grimmel; B Wagenknecht; Johannes Dichgans; Michael Weller
Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for new protein synthesis, formation of reactive oxygen species, and caspase processing.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1306-12.
1998: Wolfgang Wick; Sven Wagner; Siglinde Kerkau; Johannes Dichgans; Jörg-Christian Tonn; Michael Weller
BCL-2 promotes migration and invasiveness of human glioma cells.
FEBS letters 1998;440(3):419-24.