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Felix Wieland

Research Profile

Chemicals & Drugs

Anatomy

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Andreas Max Ernst; Moritz Hacke; Alexia Herrmann; Walter Nickel; Felix T Wieland; Sonja Zacherl; Britta Brügger
Differential transport of Influenza A neuraminidase signal anchor peptides to the plasma membrane.
Helmuth Gehart; Alexander Goginashvili; Joëlle Morvan; Rainer Beck; Maria Antonietta De Matteis; Eric Erbs; Ivan Formentini; Yannick Schwab; Felix T Wieland; Romeo Ricci
The BAR domain protein Arfaptin-1 controls secretory granule biogenesis at the trans-Golgi network.
Marco Faini; Simone Prinz; James D Riches; Martin Schorb; Felix T Wieland; Kirsten Bacia; Rainer Beck; Britta Brügger; John A G Briggs
The structures of COPI-coated vesicles reveal alternate coatomer conformations and interactions.

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All Publications

2013: Andreas Max Ernst; Moritz Hacke; Alexia Herrmann; Walter Nickel; Felix T Wieland; Sonja Zacherl; Britta Brügger
Differential transport of Influenza A neuraminidase signal anchor peptides to the plasma membrane.
FEBS letters 2013;587(9):1411-7.
2012: Helmuth Gehart; Alexander Goginashvili; Joëlle Morvan; Rainer Beck; Maria Antonietta De Matteis; Eric Erbs; Ivan Formentini; Yannick Schwab; Felix T Wieland; Romeo Ricci
The BAR domain protein Arfaptin-1 controls secretory granule biogenesis at the trans-Golgi network.
Developmental cell 2012;23(4):756-68.
2012: Marco Faini; Simone Prinz; James D Riches; Martin Schorb; Felix T Wieland; Kirsten Bacia; Rainer Beck; Britta Brügger; John A G Briggs
The structures of COPI-coated vesicles reveal alternate coatomer conformations and interactions.
Science (New York, N.Y.) 2012;336(6087):1451-4.
2011: Julia Ritzerfeld; Jeroen Strating; Koen Temmerman; Stella Tournaviti; Tao Wang; Sabine Wegehingel; Felix T Wieland; Britta Brügger; Jan Ellenberg; Holger Erfle; Jürgen Hesser; Chris Lawerenz; Beate Neumann; Rainer Pepperkok; Steffen Remmele; Walter Nickel
Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases.
Genome research 2011;21(11):1955-68.
2011: Vincent Popoff; Inge Reckmann; Britta Brügger; Andrea Hellwig; Richard A Kahn; Julian D Langer; Felix T Wieland
Several ADP-ribosylation factor (Arf) isoforms support COPI vesicle formation.
The Journal of biological chemistry 2011;286(41):35634-42.
2011: Rainer Beck; John A G Briggs; Britta Brügger; Petra Diestelkötter-Bachert; Kathrin Hoehner; Simone Prinz; Simone Röhling; Paolo Ronchi; Sonja Welsch; Frank Adolf; Felix T Wieland
Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scission.
The Journal of cell biology 2011;194(5):765-77.
2011: Monika C Sahlmüller; Jeroen Strating; Rainer Beck; Imre Berger; Britta Brügger; Priska Eckert; Mathias Haag; Andrea Hellwig; Vincent Popoff; Felix T Wieland
Recombinant heptameric coatomer complexes: novel tools to study isoform-specific functions.
Traffic (Copenhagen, Denmark) 2011;12(6):682-92.
2011: Andreas Merz; Gang Long; Marie-Sophie Hiet; Britta Brügger; Petr Chlanda; Patrice Andre; Felix T Wieland; Jacomine Krijnse-Locker; Ralf Bartenschlager
Biochemical and morphological properties of hepatitis C virus particles and determination of their lipidome.
The Journal of biological chemistry 2011;286(4):3018-32.
2010: Christof Osman; Mathias Haag; Felix T Wieland; Britta Brügger; Thomas Langer
A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4.
The EMBO journal 2010;29(12):1976-87.
2010: Rainer Beck; Britta Bruegger; Felix T Wieland
Membrane deformation and separation.
F1000 biology reports 2010;2():.
2009: Scott Emr; Benjamin S Glick; Adam D Linstedt; Jennifer Lippincott-Schwartz; Alberto Luini; Vivek Malhotra; Brad J Marsh; Akihiko Nakano; Suzanne R Pfeffer; Catherine Rabouille; James E Rothman; Graham Warren; Felix T Wieland
Journeys through the Golgi--taking stock in a new era.
The Journal of cell biology 2009;187(4):449-53.
2009: Maier Lorizate; Britta Brügger; Hisashi Akiyama; Bärbel Glass; Barbara Müller; Gregor Anderluh; Felix T Wieland; Hans-Georg Kräusslich
Probing HIV-1 membrane liquid order by Laurdan staining reveals producer cell-dependent differences.
The Journal of biological chemistry 2009;284(33):22238-47.
2009: Christoph Rutz; Ayano Satoh; Paolo Ronchi; Britta Brügger; Graham Warren; Felix T Wieland
Following the fate in vivo of COPI vesicles generated in vitro.
Traffic (Copenhagen, Denmark) 2009;10(8):994-1005.
2009: Rainer Beck; Frank Adolf; Carolin Weimer; Britta Bruegger; Felix T Wieland
ArfGAP1 activity and COPI vesicle biogenesis.
Traffic (Copenhagen, Denmark) 2009;10(3):307-15.
2009: Christof Osman; Mathias Haag; Christoph Potting; Jonathan Rodenfels; Phat Vinh Dip; Felix T Wieland; Britta Brügger; Benedikt Westermann; Thomas Langer
The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria.
The Journal of cell biology 2009;184(4):583-96.
2008: Carolin Weimer; Rainer Beck; Priska Eckert; Inge Reckmann; Jörg Moelleken; Britta Brügger; Felix T Wieland
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.
The Journal of cell biology 2008;183(4):725-35.
2008: Michael Krauss; Jun-Yong Jia; Aurélien Roux; Rainer Beck; Felix T Wieland; Pietro De Camilli; Volker Haucke
Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding.
The Journal of biological chemistry 2008;283(41):27717-23.
2008: Sandra Zitzler; Alice Hellwig; Franz-Ulrich Hartl; Felix T Wieland; Petra Diestelkötter-Bachert
Distinct binding sites for the ATPase and substrate-binding domain of human Hsp70 on the cell surface of antigen presenting cells.
Molecular immunology 2008;45(15):3974-83.
2008: Rainer Beck; Zhe Sun; Frank Adolf; Chistoph Rutz; Jochen Bassler; Klemens Wild; Irmgard Sinning; Ed Hurt; Britta Brügger; Julien Béthune; Felix T Wieland
Membrane curvature induced by Arf1-GTP is essential for vesicle formation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11731-6.
2008: Julian D Langer; Christian M Roth; Julien Béthune; Emily H Stoops; Britta Brügger; Dirk-Peter Herten; Felix T Wieland
A conformational change in the alpha-subunit of coatomer induced by ligand binding to gamma-COP revealed by single-pair FRET.
Traffic (Copenhagen, Denmark) 2008;9(4):597-607.
2008: Katarina Trajkovic; Chieh Hsu; Salvatore Chiantia; Lawrence Rajendran; Dirk Wenzel; Felix T Wieland; Petra Schwille; Britta Brügger; Mikael Simons
Ceramide triggers budding of exosome vesicles into multivesicular endosomes.
Science (New York, N.Y.) 2008;319(5867):1244-7.
2008: Lee Gyan Kwa; Dominik Wegmann; Britta Brügger; Felix T Wieland; Gerhard Wanner; Paula Braun
Mutation of a single residue, beta-glutamate-20, alters protein-lipid interactions of light harvesting complex II.
Molecular microbiology 2008;67(1):63-77.
2008: Per Haberkant; Oliver Schmitt; F-Xabier Contreras; Christoph Thiele; Kentaro Hanada; Hein Sprong; Constanze Reinhard; Felix T Wieland; Britta Brügger
Protein-sphingolipid interactions within cellular membranes.
Journal of lipid research 2008;49(1):251-62.
2007: Felix Findeisen; Jürgen U Linder; Anita Schultz; Joachim E Schultz; Britta Brügger; Felix T Wieland; Irmgard Sinning; Ivo Tews
The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid.
Journal of molecular biology 2007;369(5):1282-95.
2007: Julian D Langer; Emily H Stoops; Julien Béthune; Felix T Wieland
Conformational changes of coat proteins during vesicle formation.
FEBS letters 2007;581(11):2083-8.
2007: Zhe Sun; Frank Anderl; Kathrin Fröhlich; Liyun Zhao; Stefan Hanke; Britta Brügger; Felix T Wieland; Julien Béthune
Multiple and stepwise interactions between coatomer and ADP-ribosylation factor-1 (Arf1)-GTP.
Traffic (Copenhagen, Denmark) 2007;8(5):582-93.
2007: Xueyi Li; Dora Kaloyanova; Martin van Eijk; Ruud Eerland; Gisou van der Goot; Viola Oorschot; Judith Klumperman; Friedrich Lottspeich; Vytaute Starkuviene; Felix T Wieland; J Bernd Helms
Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure.
Molecular biology of the cell 2007;18(4):1261-71.
2007: Jörg Moelleken; Jörg Malsam; Matthew J Betts; Ali Movafeghi; Inge Reckmann; Ingrid Meissner; Andrea Hellwig; Robert B Russell; Thomas H Söllner; Britta Brügger; Felix T Wieland
Differential localization of coatomer complex isoforms within the Golgi apparatus.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4425-30.
2007: Britta Brügger; Ellen Krautkrämer; Nadine Tibroni; Claudia Elisabeth Munte; Susanne Rauch; Iris Leibrecht; Bärbel Glass; Sebastian Breuer; Matthias Geyer; Hans-Georg Kräusslich; Hans Robert Kalbitzer; Felix T Wieland; Oliver T Fackler
Human immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains.
Retrovirology 2007;4():70.
2007: Kulandaivelu S Vetrivel; Ping Gong; James W Bowen; Haipeng Cheng; Ying Chen; Meghan Carter; Phuong D Nguyen; Lisa Placanica; Felix T Wieland; Yueming Li; Maria Z Kounnas; Gopal Thinakaran
Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism.
Molecular neurodegeneration 2007;2():4.
2006: Shigeo Takamori; Matthew Holt; Katinka Stenius; Edward A Lemke; Mads Grønborg; Dietmar Riedel; Henning Urlaub; Stephan Schenck; Britta Brügger; Philippe Ringler; Shirley A Müller; Burkhard Rammner; Frauke Gräter; Jochen S Hub; Bert L de Groot; Gottfried Mieskes; Yoshinori Moriyama; Jurgen Klingauf; Helmut Grubmüller; John Edward Heuser; Felix T Wieland; Reinhard Jahn
Molecular anatomy of a trafficking organelle.
Cell 2006;127(4):831-46.
2006: Julien Béthune; Matthijs Kol; Julia Hoffmann; Inge Reckmann; Britta Brügger; Felix T Wieland
Coatomer, the coat protein of COPI transport vesicles, discriminates endoplasmic reticulum residents from p24 proteins.
Molecular and cellular biology 2006;26(21):8011-21.
2006: Sven Y Vetter; Albrecht Elsässer; Osman Tutdibi; Sabrina Lang; Wolfgang Schoels; Anja Pott; Cordula Ackermann; Constanze Reinhard; Felix T Wieland; Hugo A Katus; Wolfgang Kübler; Achim M Vogt
Brief antecedent anoxia preserves mitochondrial function after sustained undersupply: a subcellular correlate to ischemic preconditioning?
Molecular and cellular biochemistry 2006;285(1-2):191-6.
2006: Britta Brügger; Bärbel Glass; Per Haberkant; Iris Leibrecht; Felix T Wieland; Hans-Georg Kräusslich
The HIV lipidome: a raft with an unusual composition.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2641-6.
2006: Julien Béthune; Felix T Wieland; Jörg Moelleken
COPI-mediated transport.
The Journal of membrane biology 2006;211(2):65-79.
2005: Gesine Saher; Britta Brügger; Corinna Lappe-Siefke; Wiebke Möbius; Ryuichi Tozawa; Michael C Wehr; Felix T Wieland; Shun Ishibashi; Klaus-Armin Nave
High cholesterol level is essential for myelin membrane growth.
Nature neuroscience 2005;8(4):468-75.
2004: Martin Theis; Alexander Knorre; Bettina Kellersch; Jörg Moelleken; Felix T Wieland; Waldemar Kolanus; Michael Famulok
Discriminatory aptamer reveals serum response element transcription regulated by cytohesin-2.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(31):11221-6.
2004: Roger Schneiter; Britta Brügger; Clare M Amann; Glenn D Prestwich; Raquel F Epand; Günther Zellnig; Felix T Wieland; Richard M Epand
Identification and biophysical characterization of a very-long-chain-fatty-acid-substituted phosphatidylinositol in yeast subcellular membranes.
The Biochemical journal 2004;381(Pt 3):941-9.
2004: Britta Brügger; Catriona Graham; Iris Leibrecht; Enrico Mombelli; Angela Jen; Felix T Wieland; Roger Morris
The membrane domains occupied by glycosylphosphatidylinositol-anchored prion protein and Thy-1 differ in lipid composition.
The Journal of biological chemistry 2004;279(9):7530-6.
2004: Dominik Wegmann; Pablo Hess; Carola Baier; Felix T Wieland; Constanze Reinhard
Novel isotypic gamma/zeta subunits reveal three coatomer complexes in mammals.
Molecular and cellular biology 2004;24(3):1070-80.
2003: Ernstpeter Stüven; Amir Porat; Frida Shimron; Ephraim Fass; Dora Kaloyanova; Britta Brügger; Felix T Wieland; Zvulun Elazar; J Bernd Helms
Intra-Golgi protein transport depends on a cholesterol balance in the lipid membrane.
The Journal of biological chemistry 2003;278(52):53112-22.
2003: Silvia Neumann; Elisabeth Petfalski; Britta Brügger; Helge Grosshans; Felix T Wieland; David Tollervey; Ed Hurt
Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p.
EMBO reports 2003;4(12):1156-62.
2003: Cagla Eroglu; Britta Brugger; Felix T Wieland; Irmgard Sinning
Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10219-24.
2003: Anamarija Kruljac-Letunic; Jörg Moelleken; Anders Kallin; Felix T Wieland; Andree Blaukat
The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1.
The Journal of biological chemistry 2003;278(32):29560-70.
2003: Claus Rodemer; Thanh-Phuong Thai; Britta Brugger; Thomas Kaercher; Hauke Werner; Klaus-Armin Nave; Felix T Wieland; Karin Gorgas; Wilhelm W Just
Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice.
Human molecular genetics 2003;12(15):1881-95.
2003: Constanze Reinhard; Michael Schweikert; Felix T Wieland; Walter Nickel
Functional reconstitution of COPI coat assembly and disassembly using chemically defined components.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8253-7.
2002: Nicole Jenne; Karolin Frey; Britta Brugger; Felix T Wieland
Oligomeric state and stoichiometry of p24 proteins in the early secretory pathway.
The Journal of biological chemistry 2002;277(48):46504-11.
2002: Walter Nickel; Britta Brügger; Felix T Wieland
Vesicular transport: the core machinery of COPI recruitment and budding.
Journal of cell science 2002;115(Pt 16):3235-40.
2002: Heike B Eberle; Ramon L Serrano; Joachim Füllekrug; Andreas Schlosser; Wolf D Lehmann; Friedrich Lottspeich; Dora Kaloyanova; Felix T Wieland; J Bernd Helms
Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex.
Journal of cell science 2002;115(Pt 4):827-38.
2002: Michael E Young; Tatiana S Karpova; Britta Brügger; Darcy M Moschenross; Georgeann K Wang; Roger Schneiter; Felix T Wieland; John A Cooper
The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation.
Molecular and cellular biology 2002;22(3):927-34.
2001: DU Gommel; A R Memon; A Heiss; Friedrich Lottspeich; Jens Pfannstiel; Johannes Lechner; Constanze Reinhard; J Bernd Helms; Walter Nickel; Felix T Wieland
Recruitment to Golgi membranes of ADP-ribosylation factor 1 is mediated by the cytoplasmic domain of p23.
The EMBO journal 2001;20(23):6751-60.
2001: I Gkantiragas; Britta Brügger; E Stüven; Dora Kaloyanova; X Y Li; K Löhr; Friedrich Lottspeich; Felix T Wieland; J Bernd Helms
Sphingomyelin-enriched microdomains at the Golgi complex.
Molecular biology of the cell 2001;12(6):1819-33.
2001: Walter Nickel; Felix T Wieland
Receptor-dependent formation of COPI-coated vesicles from chemically defined donor liposomes.
Methods in enzymology 2001;329():388-404.
2000: I Nölte; D Jeckel; Felix T Wieland; K Sohn
Localization and topology of ratp28, a member of a novel family of putative steroid-binding proteins.
Biochimica et biophysica acta 2000;1543(1):123-30.
2000: Britta Brügger; Roger Sandhoff; Sabine Wegehingel; Karin Gorgas; Jörg Malsam; J Bernd Helms; Wolf D Lehmann; Walter Nickel; Felix T Wieland
Evidence for segregation of sphingomyelin and cholesterol during formation of COPI-coated vesicles.
The Journal of cell biology 2000;151(3):507-18.
2000: TA Fligge; Constanze Reinhard; Christoph Harter; Felix T Wieland; Michael Przybylski
Oligomerization of peptides analogous to the cytoplasmic domains of coatomer receptors revealed by mass spectrometry.
Biochemistry 2000;39(29):8491-6.
2000: M Weidler; Constanze Reinhard; G Friedrich; Felix T Wieland; Paul Rösch
Structure of the cytoplasmic domain of p23 in solution: implications for the formation of COPI vesicles.
Biochemical and biophysical research communications 2000;271(2):401-8.
2000: K D Fischer; J Bernd Helms; L Zhao; Felix T Wieland
Site-specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles.
Methods (San Diego, Calif.) 2000;20(4):455-64.
1999: Jörg Malsam; DU Gommel; Felix T Wieland; Walter Nickel
A role for ADP ribosylation factor in the control of cargo uptake during COPI-coated vesicle biogenesis.
FEBS letters 1999;462(3):267-72.
1999: Roger Schneiter; Britta Brügger; Roger Sandhoff; Günther Zellnig; A Leber; M Lampl; Karin Athenstaedt; Claudia Hrastnik; S Eder; Günther Daum; Fritz Paltauf; Felix T Wieland; Sepp D Kohlwein
Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membrane.
The Journal of cell biology 1999;146(4):741-54.
1999: Felix T Wieland; Christoph Harter
Mechanisms of vesicle formation: insights from the COP system.
Current opinion in cell biology 1999;11(4):440-6.
1999: L Zhao; J Bernd Helms; J Brunner; Felix T Wieland
GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23.
The Journal of biological chemistry 1999;274(20):14198-203.
1999: Maria Dolores Ledesma; Britta Brügger; C Bünning; Felix T Wieland; Carlos G Dotti
Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and formation of protein-lipid complexes.
The EMBO journal 1999;18(7):1761-71.
1999: DU Gommel; Lelio Orci; E M Emig; Matthew J Hannah; Mariella Ravazzola; Walter Nickel; J Bernd Helms; Felix T Wieland; K Sohn
p24 and p23, the major transmembrane proteins of COPI-coated transport vesicles, form hetero-oligomeric complexes and cycle between the organelles of the early secretory pathway.
FEBS letters 1999;447(2-3):179-85.
1999: M Bremser; Walter Nickel; M Schweikert; Mariella Ravazzola; Mylene Amherdt; C A Hughes; Thomas H Söllner; James E Rothman; Felix T Wieland
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors.
Cell 1999;96(4):495-506.
1999: Constanze Reinhard; Christoph Harter; M Bremser; Britta Brügger; K Sohn; J Bernd Helms; Felix T Wieland
Receptor-induced polymerization of coatomer.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1224-8.
1999: Roger Sandhoff; Britta Brügger; D Jeckel; Wolf D Lehmann; Felix T Wieland
Determination of cholesterol at the low picomole level by nano-electrospray ionization tandem mass spectrometry.
Journal of lipid research 1999;40(1):126-32.
1998: Irina Majoul; K Sohn; Felix T Wieland; R Pepperkok; M Pizza; J Hillemann; Hans-Dieter Söling
KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p.
The Journal of cell biology 1998;143(3):601-12.
1998: Walter Nickel; Britta Brügger; Felix T Wieland
Protein and lipid sorting between the endoplasmic reticulum and the Golgi complex.
Seminars in cell & developmental biology 1998;9(5):493-501.
1998: Walter Nickel; Jörg Malsam; Karin Gorgas; Mariella Ravazzola; N Jenne; J Bernd Helms; Felix T Wieland
Uptake by COPI-coated vesicles of both anterograde and retrograde cargo is inhibited by GTPgammaS in vitro.
Journal of cell science 1998;111 ( Pt 20)():3081-90.
1998: Christoph Harter; Felix T Wieland
A single binding site for dilysine retrieval motifs and p23 within the gamma subunit of coatomer.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11649-54.
1998: J Bernd Helms; D Helms-Brons; Britta Brügger; I Gkantiragas; H Eberle; Walter Nickel; B Nürnberg; Hans-Hermann Gerdes; Felix T Wieland
A putative heterotrimeric G protein inhibits the fusion of COPI-coated vesicles. Segregation of heterotrimeric G proteins from COPI-coated vesicles.
The Journal of biological chemistry 1998;273(24):15203-8.
1998: Walter Nickel; Felix T Wieland
Biosynthetic protein transport through the early secretory pathway.
Histochemistry and cell biology 1998;109(5-6):477-86.
1998: M Passreiter; M Anton; Dorothee Lay; R Frank; Christoph Harter; Felix T Wieland; Karin Gorgas; Wilhelm W Just
Peroxisome biogenesis: involvement of ARF and coatomer.
The Journal of cell biology 1998;141(2):373-83.
1998: J Pavel; Christoph Harter; Felix T Wieland
Reversible dissociation of coatomer: functional characterization of a beta/delta-coat protein subcomplex.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2140-5.
1998: H Lannert; Karin Gorgas; I Meissner; Felix T Wieland; D Jeckel
Functional organization of the Golgi apparatus in glycosphingolipid biosynthesis. Lactosylceramide and subsequent glycosphingolipids are formed in the lumen of the late Golgi.
The Journal of biological chemistry 1998;273(5):2939-46.
1997: Walter Nickel; K Sohn; C Bünning; Felix T Wieland
p23, a major COPI-vesicle membrane protein, constitutively cycles through the early secretory pathway.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11393-8.
1997: Walter Nickel; Felix T Wieland
Biogenesis of COPI-coated transport vesicles.
FEBS letters 1997;413(3):395-400.
1997: L Zhao; J Bernd Helms; Britta Brügger; Christoph Harter; B Martoglio; R Graf; J Brunner; Felix T Wieland
Direct and GTP-dependent interaction of ADP ribosylation factor 1 with coatomer subunit beta.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4418-23.
1997: Britta Brügger; Gerhard Erben; Roger Sandhoff; Felix T Wieland; Wolf D Lehmann
Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2339-44.
1996: K Sohn; L Orci; Mariella Ravazzola; Mylene Amherdt; M Bremser; F Lottspeich; Klaus Fiedler; J Bernd Helms; Felix T Wieland
A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding.
The Journal of cell biology 1996;135(5):1239-48.
1996: D Faulstich; S Auerbach; L Orci; Mariella Ravazzola; S Wegchingel; F Lottspeich; G Stenbeck; Christoph Harter; Felix T Wieland; H Tschochner
Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex.
The Journal of cell biology 1996;135(1):53-61.
1996: Walter Nickel; J Bernd Helms; R E Kneusel; Felix T Wieland
Forskolin stimulates detoxification of brefeldin A.
The Journal of biological chemistry 1996;271(27):15870-3.
1996: Christoph Harter; Felix T Wieland
The secretory pathway: mechanisms of protein sorting and transport.
Biochimica et biophysica acta 1996;1286(2):75-93.
1996: James E Rothman; Felix T Wieland
Protein sorting by transport vesicles.
Science (New York, N.Y.) 1996;272(5259):227-34.
1996: Christoph Harter; J Pavel; F Coccia; E Draken; S Wegehingel; H Tschochner; Felix T Wieland
Nonclathrin coat protein gamma, a subunit of coatomer, binds to the cytoplasmic dilysine motif of membrane proteins of the early secretory pathway.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1902-6.
1995: M Murata; J Peränen; R Schreiner; Felix T Wieland; Teymuras V Kurzchalia; Kai Simons
VIP21/caveolin is a cholesterol-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10339-43.
1995: Iris Ansorge; D Jeckel; Felix T Wieland; Klaus Lingelbach
Plasmodium falciparum-infected erythrocytes utilize a synthetic truncated ceramide precursor for synthesis and secretion of truncated sphingomyelin.
The Biochemical journal 1995;308 ( Pt 1)():335-41.
1995: B Gerich; L Orci; H Tschochner; F Lottspeich; Mariella Ravazzola; M Amherdt; Felix T Wieland; Christoph Harter
Non-clathrin-coat protein alpha is a conserved subunit of coatomer and in Saccharomyces cerevisiae is essential for growth.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3229-33.
1994: K van Leyen; M Widemann; Felix T Wieland
Glycotripeptides are released by yeast but not by mammalian microsomes.
FEBS letters 1994;355(2):147-50.
1994: K van Leyen; Felix T Wieland
Complete Golgi passage of glycotripeptides generated in the endoplasmic reticulum of mammalian cells.
FEBS letters 1994;352(2):211-5.
1994: H Lannert; C Bünning; D Jeckel; Felix T Wieland
Lactosylceramide is synthesized in the lumen of the Golgi apparatus.
FEBS letters 1994;342(1):91-6.
1994: S Hara-Kuge; O Kuge; L Orci; Mylene Amherdt; Mariella Ravazzola; Felix T Wieland; James E Rothman
En bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles.
The Journal of cell biology 1994;124(6):883-92.
1994: R Schreiner; E Schnabel; Felix T Wieland
Novel N-glycosylation in eukaryotes: laminin contains the linkage unit beta-glucosylasparagine.
The Journal of cell biology 1994;124(6):1071-81.
1993: U Kärcher; H Schröder; E Haslinger; G Allmaier; R Schreiner; Felix T Wieland; A Haselbeck; H König
Primary structure of the heterosaccharide of the surface glycoprotein of Methanothermus fervidus.
The Journal of biological chemistry 1993;268(36):26821-6.
1993: O Kuge; S Hara-Kuge; L Orci; Mariella Ravazzola; Mylene Amherdt; G Tanigawa; Felix T Wieland; James E Rothman
zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.
The Journal of cell biology 1993;123(6 Pt 2):1727-34.
1993: Christoph Harter; E Draken; F Lottspeich; Felix T Wieland
Yeast coatomer contains a subunit homologous to mammalian beta'-COP.
FEBS letters 1993;332(1-2):71-3.
1993: G Stenbeck; Christoph Harter; A Brecht; D Herrmann; F Lottspeich; L Orci; Felix T Wieland
beta'-COP, a novel subunit of coatomer.
The EMBO journal 1993;12(7):2841-5.
1993: Krisztina Káldi; P Diestelkötter; G Stenbeck; S Auerbach; U Jäkle; H J Mägert; Felix T Wieland; Wilhelm W Just
Membrane topology of the 22 kDa integral peroxisomal membrane protein.
FEBS letters 1993;315(3):217-22.
1993: D Jeckel; Felix T Wieland
Truncated ceramide analogs as probes for sphingolipid biosynthesis and transport.
Advances in lipid research 1993;26():143-60.
1992: G Stenbeck; R Schreiner; D Herrmann; S Auerbach; F Lottspeich; James E Rothman; Felix T Wieland
Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p.
FEBS letters 1992;314(2):195-8.
1992: W van't Hof; J Silvius; Felix T Wieland; Gerrit van Meer
Epithelial sphingolipid sorting allows for extensive variation of the fatty acyl chain and the sphingosine backbone.
The Biochemical journal 1992;283 ( Pt 3)():913-7.
1992: A Brüning; T Ishikawa; R E Kneusel; Ulrich Matern; F Lottspeich; Felix T Wieland
Brefeldin A binds to glutathione S-transferase and is secreted as glutathione and cysteine conjugates by Chinese hamster ovary cells.
The Journal of biological chemistry 1992;267(11):7726-32.
1992: D Jeckel; A Karrenbauer; Koert Burger; Gerrit van Meer; Felix T Wieland
Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions.
The Journal of cell biology 1992;117(2):259-67.
1992: A Brüning; A Karrenbauer; E Schnabel; Felix T Wieland
Brefeldin A-induced increase of sphingomyelin synthesis. Assay for the action of the antibiotic in mammalian cells.
The Journal of biological chemistry 1992;267(8):5052-5.
1992: Felix T Wieland
Transfer of bulk markers from endoplasmic reticulum to plasma membrane.
Methods in enzymology 1992;219():189-98.
1991: T Serafini; G Stenbeck; A Brecht; F Lottspeich; L Orci; James E Rothman; Felix T Wieland
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin.
Nature 1991;349(6306):215-20.
1990: J Bernd Helms; A Karrenbauer; Karel W A Wirtz; James E Rothman; Felix T Wieland
Reconstitution of steps in the constitutive secretory pathway in permeabilized cells. Secretion of glycosylated tripeptide and truncated sphingomyelin.
The Journal of biological chemistry 1990;265(32):20027-32.
1990: A Karrenbauer; D Jeckel; Wilhelm W Just; R Birk; R R Schmidt; James E Rothman; Felix T Wieland
The rate of bulk flow from the Golgi to the plasma membrane.
Cell 1990;63(2):259-67.
1990: D Jeckel; A Karrenbauer; R Birk; R R Schmidt; Felix T Wieland
Sphingomyelin is synthesized in the cis Golgi.
FEBS letters 1990;261(1):155-7.
1988: M R Block; Benjamin S Glick; C A Wilcox; Felix T Wieland; James E Rothman
Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(21):7852-6.