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Tadeusz Wieloch

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Philipp Mergenthaler; Claudia Muselmann; Ulrich Dirnagl; Nickolay K Isaev; Andreas Meisel; Juliane Sünwoldt; Tadeusz Wieloch; Karsten Ruscher
A functional role of the cyclin-dependent kinase inhibitor 1 (p21(WAF1/CIP1)) for neuronal preconditioning.
Johan Undén; Tadeusz Wieloch; John-Kalle Länsberg; Karsten Ruscher; Carin Sjölund; Bertil Romner
Post-ischemic continuous infusion of erythropoeitin enhances recovery of lost memory function after global cerebral ischemia in the rat.
Gregor Tomasevic; Tadeusz Wieloch; Harry van Steeg; Helmut L Laurer; Gustav Mattiasson; Tracy K McIntosh
Delayed neuromotor recovery and increased memory acquisition dysfunction following experimental brain trauma in mice lacking the DNA repair gene XPA.

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2013: Philipp Mergenthaler; Claudia Muselmann; Ulrich Dirnagl; Nickolay K Isaev; Andreas Meisel; Juliane Sünwoldt; Tadeusz Wieloch; Karsten Ruscher
A functional role of the cyclin-dependent kinase inhibitor 1 (p21(WAF1/CIP1)) for neuronal preconditioning.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(3):351-5.
2013: Johan Undén; Tadeusz Wieloch; John-Kalle Länsberg; Karsten Ruscher; Carin Sjölund; Bertil Romner
Post-ischemic continuous infusion of erythropoeitin enhances recovery of lost memory function after global cerebral ischemia in the rat.
BMC neuroscience 2013;14():27.
2012: Gregor Tomasevic; Tadeusz Wieloch; Harry van Steeg; Helmut L Laurer; Gustav Mattiasson; Tracy K McIntosh
Delayed neuromotor recovery and increased memory acquisition dysfunction following experimental brain trauma in mice lacking the DNA repair gene XPA.
Journal of neurosurgery 2012;116(6):1368-78.
2012: João R Gomes; Mário Grãos; Ana R Inácio; Carlos V Melo; Patrícia Monteiro; Maria J Pinto; Tadeusz Wieloch; Ramiro D Almeida; João T Costa; Federico Felizzi; Carlos B Duarte
Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(13):4610-22.
2012: Karsten Ruscher; Enida Kuric; Tadeusz Wieloch
Levodopa treatment improves functional recovery after experimental stroke.
Stroke; a journal of cerebral circulation 2012;43(2):507-13.
2012: Karsten Ruscher; Kristian Valind; Ana R Inácio; Enida Kuric; Arman Rowshan Ravan; Tadeusz Wieloch
Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke.
PloS one 2012;7(9):e45118.
2011: Andrea C Lobo; Miranda Mele; AE Santos; Tadeusz Wieloch; Ben A Bahr; Ana Luísa Carvalho; Tatiana Catarino; Pedro Fernandez; João R Gomes; Ana R Inácio; Carlos B Duarte
Cleavage of the vesicular glutamate transporters under excitotoxic conditions.
Neurobiology of disease 2011;44(3):292-303.
2011: Krzysztof Kucharz; Tadeusz Wieloch; H Toresson
Potassium-induced structural changes of the endoplasmic reticulum in pyramidal neurons in murine organotypic hippocampal slices.
Journal of neuroscience research 2011;89(8):1150-9.
2011: João R Gomes; Andrea C Lobo; Carlos V Melo; Ana R Inácio; Jiro Takano; Nobuhisa Iwata; Takaomi C Saido; Luis de Almeida; Tadeusz Wieloch; Carlos B Duarte
Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(12):4622-35.
2011: Karsten Ruscher; Mehrdad Shamloo; Mattias Rickhag; Istvan Ladunga; Liza Soriano; Lennart Gisselsson; H Toresson; Lily Ruslim-Litrus; Donna Oksenberg; Roman Urfer; Barbro B Johansson; Karoly Nikolich; Tadeusz Wieloch
The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke.
Brain : a journal of neurology 2011;134(Pt 3):732-46.
2011: Ana R Inácio; Karsten Ruscher; Tadeusz Wieloch
Enriched environment downregulates macrophage migration inhibitory factor and increases parvalbumin in the brain following experimental stroke.
Neurobiology of disease 2011;41(2):270-8.
2011: Karsten Ruscher; Eduarda Fernandes; João Paulo Capela; Maria de Lourdes Bastos; Tadeusz Wieloch; Ulrich Dirnagl; Andreas Meisel; Félix Carvalho
Effect of 3,4-methylenedioxyamphetamine on dendritic spine dynamics in rat neocortical neurons--involvement of heat shock protein 27.
Brain research 2011;1370():43-52.
2010: Gregor Tomasevic; Ramesh Raghupathi; Uwe Scherbel; Tadeusz Wieloch; Tracy K McIntosh
Deletion of the p53 tumor suppressor gene improves neuromotor function but does not attenuate regional neuronal cell loss following experimental brain trauma in mice.
Journal of neuroscience research 2010;88(15):3414-23.
2010: Taku Ishizaki; Agnes Erickson; Enida Kuric; Mehrdad Shamloo; Ikuko Hara-Nishimura; Ana Rita Lourenço Inácio; Tadeusz Wieloch; Karsten Ruscher
The asparaginyl endopeptidase legumain after experimental stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(10):1756-66.
2010: Karsten Ruscher; Agnes Erickson; Enida Kuric; Ana R Inácio; Tadeusz Wieloch
Effects of chronic Clozapine administration on apolipoprotein D levels and on functional recovery following experimental stroke.
Brain research 2010;1321():152-63.
2010: L Lennart Gisselsson; H Toresson; Karsten Ruscher; Tadeusz Wieloch
Rho kinase inhibition protects CA1 cells in organotypic hippocampal slices during in vitro ischemia.
Brain research 2010;1316():92-100.
2010: Charmaine Childs; Tadeusz Wieloch; Fiona Lecky; Graham Machin; Bridget Harris; Nino Stocchetti
Report of a consensus meeting on human brain temperature after severe traumatic brain injury: its measurement and management during pyrexia.
Frontiers in neurology 2010;1():146.
2010: Tina Markus; Stefan R Hansson; Tobias Cronberg; Corrado M Cilio; Tadeusz Wieloch; David Ley
β-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices.
Journal of neuroinflammation 2010;7():94.
2009: Karsten Ruscher; Emelie Johannesson; Elena Brugiere; Agnes Erickson; Mattias Rickhag; Tadeusz Wieloch
Enriched environment reduces apolipoprotein E (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(11):1796-805.
2009: Tina Markus; Tobias Cronberg; Corrado Cilio; Cornelis Pronk; Tadeusz Wieloch; David Ley
Tumor necrosis factor receptor-1 is essential for LPS-induced sensitization and tolerance to oxygen-glucose deprivation in murine neonatal organotypic hippocampal slices.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(1):73-86.
2008: Tomas Deierborg; Tomas Deierborg Olsson; Tadeusz Wieloch; Sabrina Diano; Craig H Warden; Tamas L Horvath; Gustav Mattiasson
Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(6):1186-95.
2008: Mattias Rickhag; Tomas Deierborg; Shutish Patel; Karsten Ruscher; Tadeusz Wieloch
Apolipoprotein D is elevated in oligodendrocytes in the peri-infarct region after experimental stroke: influence of enriched environment.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(3):551-62.
2008: Matthias Endres; Britta Engelhardt; Jari Koistinaho; Olle Lindvall; Stephen Meairs; Jay P Mohr; Anna Planas; Nancy Rothwell; Markus Schwaninger; Martin E Schwab; Denis Vivien; Tadeusz Wieloch; Ulrich Dirnagl
Improving outcome after stroke: overcoming the translational roadblock.
Cerebrovascular diseases (Basel, Switzerland) 2008;25(3):268-78.
2007: Maria Teilum; Morten Krogh; Tadeusz Wieloch; Gustav Mattiasson
Hypothermia affects translocation of numerous cytoplasmic proteins following global cerebral ischemia.
Journal of proteome research 2007;6(7):2822-32.
2007: Mattias Rickhag; Maria Teilum; Tadeusz Wieloch
Rapid and long-term induction of effector immediate early genes (BDNF, Neuritin and Arc) in peri-infarct cortex and dentate gyrus after ischemic injury in rat brain.
Brain research 2007;1151():203-10.
2006: Mehrdad Shamloo; Liza Soriano; David von Schack; Mattias Rickhag; Daniel J Chin; Mirella Gonzalez-Zulueta; Gunilla Gido; Roman Urfer; Tadeusz Wieloch; Karoly Nikolich
Npas4, a novel helix-loop-helix PAS domain protein, is regulated in response to cerebral ischemia.
The European journal of neuroscience 2006;24(10):2705-20.
2006: Josefine Nygren; Tadeusz Wieloch; Jelena Pesic; Patrik Brundin; Tomas Deierborg
Enriched environment attenuates cell genesis in subventricular zone after focal ischemia in mice and decreases migration of newborn cells to the striatum.
Stroke; a journal of cerebral circulation 2006;37(11):2824-9.
2006: Patrik Brundin; M Angela Cenci; Tadeusz Wieloch
On the move to stimulate cell plasticity in the substantia nigra in Parkinson's disease.
Experimental neurology 2006;201(1):1-6.
2006: Josefine Nygren; Merab Kokaia; Tadeusz Wieloch
Decreased expression of brain-derived neurotrophic factor in BDNF(+/-) mice is associated with enhanced recovery of motor performance and increased neuroblast number following experimental stroke.
Journal of neuroscience research 2006;84(3):626-31.
2006: Tadeusz Wieloch; Karoly Nikolich
Mechanisms of neural plasticity following brain injury.
Current opinion in neurobiology 2006;16(3):258-64.
2006: Mats Allers; Fredrik Boris-Möller; Anders Lunderquist; Tadeusz Wieloch
A new method of selective, rapid cooling of the brain: an experimental study.
Cardiovascular and interventional radiology 2006;29(2):260-3.
2006: Mattias Rickhag; Tadeusz Wieloch; Gunilla Gidö; Eskil Elmér; Morten Krogh; Joseph Murray; Scott Lohr; Hans Bitter; Daniel J Chin; David von Schack; Mehrdad Shamloo; Karoly Nikolich
Comprehensive regional and temporal gene expression profiling of the rat brain during the first 24 h after experimental stroke identifies dynamic ischemia-induced gene expression patterns, and reveals a biphasic activation of genes in surviving tissue.
Journal of neurochemistry 2006;96(1):14-29.
2005: Mehrdad Shamloo; Liza Soriano; Tadeusz Wieloch; Karoly Nikolich; Roman Urfer; Donna Oksenberg
Death-associated protein kinase is activated by dephosphorylation in response to cerebral ischemia.
The Journal of biological chemistry 2005;280(51):42290-9.
2005: Josefine Nygren; Tadeusz Wieloch
Enriched environment enhances recovery of motor function after focal ischemia in mice, and downregulates the transcription factor NGFI-A.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(12):1625-33.
2005: Anna Rytter; Carla M P Cardoso; Petra Johansson; Tobias Cronberg; Magnus J Hansson; Gustav Mattiasson; Eskil Elmér; Tadeusz Wieloch
The temperature dependence and involvement of mitochondria permeability transition and caspase activation in damage to organotypic hippocampal slices following in vitro ischemia.
Journal of neurochemistry 2005;95(4):1108-17.
2005: L Lennart Gisselsson; Andrew Matus; Tadeusz Wieloch
Actin redistribution underlies the sparing effect of mild hypothermia on dendritic spine morphology after in vitro ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(10):1346-55.
2005: Tobias Cronberg; Anna Rytter; Tadeusz Wieloch
Chelation of intracellular calcium reduces cell death after hyperglycemic in vitro ischemia in murine hippocampal slice cultures.
Brain research 2005;1049(1):120-7.
2005: Tobias Cronberg; Kimmo Jensen; Anna Rytter; Tadeusz Wieloch
Selective sparing of hippocampal CA3 cells following in vitro ischemia is due to selective inhibition by acidosis.
The European journal of neuroscience 2005;22(2):310-6.
2005: Jenny Karlsson; Asa Petersén; Gunilla Gidö; Tadeusz Wieloch; Patrik Brundin
Combining neuroprotective treatment of embryonic nigral donor tissue with mild hypothermia of the graft recipient.
Cell transplantation 2005;14(5):301-9.
2004: Jonathan Lifshitz; Patrick G Sullivan; David A Hovda; Tadeusz Wieloch; Tracy K McIntosh
Mitochondrial damage and dysfunction in traumatic brain injury.
Mitochondrion 2004;4(5-6):705-13.
2004: Tomas Olsson; Tobias Cronberg; Anna Rytter; Fredrik Asztély; Bertil B. Fredholm; Maj-Lis Smith; Tadeusz Wieloch
Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro.
The European journal of neuroscience 2004;20(5):1197-204.
2004: Hans Friberg; Johan Herlitz; Sten Rubertsson; Tadeusz Wieloch
[Therapeutic hypothermia after cardiac arrest--a new link in the chain can save life].
Läkartidningen 2004;101(30-31):2412-6.
2004: Tobias Cronberg; Anna Rytter; Fredrik Asztély; Anna Söder; Tadeusz Wieloch
Glucose but not lactate in combination with acidosis aggravates ischemic neuronal death in vitro.
Stroke; a journal of cerebral circulation 2004;35(3):753-7.
2004: Tomas Olsson; Oskar Hansson; Jesper Nylandsted; Marja Jäättelä; Maj-Lis Smith; Tadeusz Wieloch
Lack of neuroprotection by heat shock protein 70 overexpression in a mouse model of global cerebral ischemia.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2004;154(4):442-9.
2004: Junichi Kurihara; Ken-ichiro Katsura; Bo K Siesjö; Tadeusz Wieloch
Hyperglycemia and hypercapnia differently affect post-ischemic changes in protein kinases and protein phosphorylation in the rat cingulate cortex.
Brain research 2004;995(2):218-25.
2004: T Olsson; Josefine Nygren; K Håkansson; C Lundblad; A Grubb; M-L Smith; Tadeusz Wieloch
Gene deletion of cystatin C aggravates brain damage following focal ischemia but mitigates the neuronal injury after global ischemia in the mouse.
Neuroscience 2004;128(1):65-71.
2004: Shohei Matsumoto; Mehrdad Shamloo; Eriko Matsumoto; Atsushi Isshiki; Tadeusz Wieloch
Protein kinase C-gamma and calcium/calmodulin-dependent protein kinase II-alpha are persistently translocated to cell membranes of the rat brain during and after middle cerebral artery occlusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(1):54-61.
2003: Gustav Mattiasson; Hans Friberg; Magnus Hansson; Eskil Elmér; Tadeusz Wieloch
Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation.
Journal of neurochemistry 2003;87(2):532-44.
2003: Tomas Olsson; Tadeusz Wieloch; Maj-Lis Smith
Brain damage in a mouse model of global cerebral ischemia. Effect of NMDA receptor blockade.
Brain research 2003;982(2):260-9.
2003: Gustav Mattiasson; Mehrdad Shamloo; Gunilla Gido; Kavitha Mathi; Gregor Tomasevic; Saili Yi; Craig H Warden; Roger F Castilho; Thorsten Melcher; Mirella Gonzalez-Zulueta; Karoly Nikolich; Tadeusz Wieloch
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma.
Nature medicine 2003;9(8):1062-8.
2003: Michel Ferrand-Drake; Changlian Zhu; Gunilla Gidö; Anders J Hansen; Jan-Olof Karlsson; Ben A Bahr; Naoufal Zamzami; Guido Kroemer; Pak H Chan; Tadeusz Wieloch; Klas Blomgren
Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia.
Journal of neurochemistry 2003;85(6):1431-42.
2003: Malcolm R Macleod; Inga-Maj Johansson; Ingegerd Söderström; Maggie Lai; Gunilla Gidö; Tadeusz Wieloch; Jonathan R Seckl; Tommy Olsson
Mineralocorticoid receptor expression and increased survival following neuronal injury.
The European journal of neuroscience 2003;17(8):1549-55.
2003: Jonathan Lifshitz; Hans Friberg; Robert W Neumar; Ramesh Raghupathi; Frank A Welsh; Paul A Janmey; Kathryn E Saatman; Tadeusz Wieloch; M Sean Grady; Tracy K McIntosh
Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(2):219-31.
2003: Magnus J Hansson; Tanja Persson; Hans Friberg; Marcus F Keep; Anthony Rees; Tadeusz Wieloch; Eskil Elmér
Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria.
Brain research 2003;960(1-2):99-111.
2003: Anna Rytter; Tobias Cronberg; Fredrik Asztély; Sailasree Nemali; Tadeusz Wieloch
Mouse hippocampal organotypic tissue cultures exposed to in vitro "ischemia" show selective and delayed CA1 damage that is aggravated by glucose.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(1):23-33.
2002: Shohei Matsumoto; Atsushi Isshiki; Yasuo Watanabe; Tadeusz Wieloch
Restricted clinical efficacy of cyclosporin A on rat transient middle cerebral artery occlusion.
Life sciences 2002;72(4-5):591-600.
2002: Hans Friberg; Tadeusz Wieloch; Roger F Castilho
Mitochondrial oxidative stress after global brain ischemia in rats.
Neuroscience letters 2002;334(2):111-4.
2002: Shohei Matsumoto; Mehrdad Shamloo; Atsushi Isshiki; Tadeusz Wieloch
Persistent phosphorylation of synaptic proteins following middle cerebral artery occlusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(9):1107-13.
2002: Emelie Stenman; Malin Malmsjö; Erik Uddman; Gunilla Gidö; Tadeusz Wieloch; Lars Edvinsson
Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat.
Stroke; a journal of cerebral circulation 2002;33(9):2311-6.
2002: Hans Friberg; Tadeusz Wieloch
Mitochondrial permeability transition in acute neurodegeneration.
Biochimie 2002;84(2-3):241-50.
2001: Tadeusz Wieloch; Fredrik Boris-Möller
[High time to test hypothermia in the treatment of stroke].
Läkartidningen 2001;98(18):2172-5.
2001: MF Philips; Gustav Mattiasson; Tadeusz Wieloch; A Björklund; Barbro B Johansson; Gregor Tomasevic; A Martínez-Serrano; Philipp M Lenzlinger; Grant P Sinson; M Sean Grady; Tracy K McIntosh
Neuroprotective and behavioral efficacy of nerve growth factor-transfected hippocampal progenitor cell transplants after experimental traumatic brain injury.
Journal of neurosurgery 2001;94(5):765-74.
2001: P Bentzer; Gustav Mattiasson; Tracy K McIntosh; Tadeusz Wieloch; P O Grande
Infusion of prostacyclin following experimental brain injury in the rat reduces cortical lesion volume.
Journal of neurotrauma 2001;18(3):275-85.
2001: T Sakai; K J Johnson; Michihiro Murozono; K Sakai; Mark Magnuson; Tadeusz Wieloch; Tobias Cronberg; Atsushi Isshiki; H P Erickson; Reinhard Fässler
Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis.
Nature medicine 2001;7(3):324-30.
2000: Jenny Karlsson; Mia Emgård; Gunilla Gidö; Tadeusz Wieloch; Patrik Brundin
Increased survival of embryonic nigral neurons when grafted to hypothermic rats.
Neuroreport 2000;11(8):1665-8.
2000: Asa Petersén; Roger F Castilho; Oskar Hansson; Tadeusz Wieloch; Patrik Brundin
Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons.
Brain research 2000;857(1-2):20-9.
2000: Gunilla Gidö; Tobias Cronberg; Tadeusz Wieloch
The effect of alpha-phenyl-tert-butyl nitrone (PBN) on free radical formation in transient focal ischaemia measured by microdialysis and 3,4-dihydroxybenzoate formation.
Acta physiologica Scandinavica 2000;168(2):277-85.
2000: Gustav Mattiasson; M F Philips; Gregor Tomasevic; Barbro B Johansson; Tadeusz Wieloch; Tracy K McIntosh
The rotating pole test: evaluation of its effectiveness in assessing functional motor deficits following experimental head injury in the rat.
Journal of neuroscience methods 2000;95(1):75-82.
2000: Mehrdad Shamloo; F Kamme; Tadeusz Wieloch
Subcellular distribution and autophosphorylation of calcium/calmodulin-dependent protein kinase II-alpha in rat hippocampus in a model of ischemic tolerance.
Neuroscience 2000;96(4):665-74.
1999: Ken-ichiro Katsura; Junichi Kurihara; Bo K Siesjö; Tadeusz Wieloch
Acidosis enhances translocation of protein kinase C but not Ca(2+)/calmodulin-dependent protein kinase II to cell membranes during complete cerebral ischemia.
Brain research 1999;849(1-2):119-27.
1999: Leonid Georgievich Khaspekov; Hans Friberg; AP Halestrap; I Viktorov; Tadeusz Wieloch
Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons.
The European journal of neuroscience 1999;11(9):3194-8.
1999: Gregor Tomasevic; Mehrdad Shamloo; D Israeli; Tadeusz Wieloch
Activation of p53 and its target genes p21(WAF1/Cip1) and PAG608/Wig-1 in ischemic preconditioning.
Brain research. Molecular brain research 1999;70(2):304-13.
1999: JH Laake; Finn-Mogens Haug; Tadeusz Wieloch; Ole Petter Ottersen
A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence.
Brain research. Brain research protocols 1999;4(2):173-84.
1999: Shohei Matsumoto; Hans Friberg; Michel Ferrand-Drake; Tadeusz Wieloch
Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(7):736-41.
1999: Hans Friberg; CP Connern; AP Halestrap; Tadeusz Wieloch
Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability.
Journal of neurochemistry 1999;72(6):2488-97.
1999: Mehrdad Shamloo; Tadeusz Wieloch
Rapid decline in protein kinase Cgamma levels in the synaptosomal fraction of rat hippocampus after ischemic preconditioning.
Neuroreport 1999;10(5):931-5.
1999: Gregor Tomasevic; F Kamme; P Stubberöd; M Wieloch; Tadeusz Wieloch
The tumor suppressor p53 and its response gene p21WAF1/Cip1 are not markers of neuronal death following transient global cerebral ischemia.
Neuroscience 1999;90(3):781-92.
1999: Mehrdad Shamloo; Tadeusz Wieloch
Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(2):173-83.
1999: Michel Ferrand-Drake; Tadeusz Wieloch
The time-course of DNA fragmentation in the choroid plexus and the CA1 region following transient global ischemia in the rat brain. The effect of intra-ischemic hypothermia.
Neuroscience 1999;93(2):537-49.
1999: Mehrdad Shamloo; Anna Rytter; Tadeusz Wieloch
Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning.
Neuroscience 1999;93(1):81-8.
1999: Michel Ferrand-Drake; Hans Friberg; Tadeusz Wieloch
Mitochondrial permeability transition induced DNA-fragmentation in the rat hippocampus following hypoglycemia.
Neuroscience 1999;90(4):1325-38.
1998: Fredrik Boris-Möller; F Kamme; Tadeusz Wieloch
The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat.
Brain research. Molecular brain research 1998;63(1):163-73.
1998: Tracy K McIntosh; M Juhler; Tadeusz Wieloch
Novel pharmacologic strategies in the treatment of experimental traumatic brain injury: 1998.
Journal of neurotrauma 1998;15(10):731-69.
1998: Gregor Tomasevic; F Kamme; Tadeusz Wieloch
Changes in proliferating cell nuclear antigen, a protein involved in DNA repair, in vulnerable hippocampal neurons following global cerebral ischemia.
Brain research. Molecular brain research 1998;60(2):168-76.
1998: E Rundén; Per O Seglen; Finn-Mogens Haug; Ole Petter Ottersen; Tadeusz Wieloch; Mehrdad Shamloo; JH Laake
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(18):7296-305.
1998: Fredrik Boris-Möller; Tadeusz Wieloch
The effect of 4 beta-phorbol-12,13-dibutyrate and staurosporine on the extracellular glutamate levels during ischemia in the rat striatum.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1998;35(1-3):133-47.
1998: Fredrik Boris-Möller; Tadeusz Wieloch
Changes in the extracellular levels of glutamate and aspartate during ischemia and hypoglycemia. Effects of hypothermia.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1998;121(3):277-84.
1998: Hans Friberg; Michel Ferrand-Drake; F Bengtsson; AP Halestrap; Tadeusz Wieloch
Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(14):5151-9.
1998: Leonid Georgievich Khaspekov; Mehrdad Shamloo; I Victorov; Tadeusz Wieloch
Sublethal in vitro glucose-oxygen deprivation protects cultured hippocampal neurons against a subsequent severe insult.
Neuroreport 1998;9(7):1273-6.
1998: M Cardell; AS Landsend; J Eidet; Tadeusz Wieloch; TW Blackstad; Ole Petter Ottersen
High resolution immunogold analysis reveals distinct subcellular compartmentation of protein kinase C gamma and delta in rat Purkinje cells.
Neuroscience 1998;82(3):709-25.
1996: F Kamme; Tadeusz Wieloch
Induction of junD mRNA after transient forebrain ischemia in the rat. Effect of hypothermia.
Brain research. Molecular brain research 1996;43(1-2):51-6.
1996: C Coimbra; Fredrik Boris-Möller; M Drake; Tadeusz Wieloch
Diminished neuronal damage in the rat brain by late treatment with the antipyretic drug dipyrone or cooling following cerebral ischemia.
Acta neuropathologica 1996;92(5):447-53.
1996: M Drake; H Friberg; Fredrik Boris-Möller; K Sakata; Tadeusz Wieloch
The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain.
Acta physiologica Scandinavica 1996;158(2):155-9.
1996: C Coimbra; M Drake; Fredrik Boris-Möller; Tadeusz Wieloch
Long-lasting neuroprotective effect of postischemic hypothermia and treatment with an anti-inflammatory/antipyretic drug. Evidence for chronic encephalopathic processes following ischemia.
Stroke; a journal of cerebral circulation 1996;27(9):1578-85.
1996: O G Nilsson; Hans Säveland; Fredrik Boris-Möller; Lennart Brandt; Tadeusz Wieloch
Increased levels of glutamate in patients with subarachnoid haemorrhage as measured by intracerebral microdialysis.
Acta neurochirurgica. Supplement 1996;67():45-7.
1996: Tadeusz Wieloch; Bingren Hu; A Boris-Möller; M Cardell; F Kamme; J Kurihara; K Sakata
Intracellular signal transduction in the postischemic brain.
Advances in neurology 1996;71():371-87; discussion 387-8.
1996: F Kamme; Tadeusz Wieloch
The effect of hypothermia on protein synthesis and the expression of immediate early genes following transient cerebral ischemia.
Advances in neurology 1996;71():199-206; discussion 206-7.
1996: Hans Säveland; O G Nilsson; Fredrik Boris-Möller; Tadeusz Wieloch; Lennart Brandt
Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage.
Neurosurgery 1996;38(1):12-9; discussion 19-20.
1995: Bingren Hu; F Kamme; Tadeusz Wieloch
Alterations of Ca2+/calmodulin-dependent protein kinase II and its messenger RNA in the rat hippocampus following normo- and hypothermic ischemia.
Neuroscience 1995;68(4):1003-16.
1995: F Kamme; K Campbell; Tadeusz Wieloch
Biphasic expression of the fos and jun families of transcription factors following transient forebrain ischaemia in the rat. Effect of hypothermia.
The European journal of neuroscience 1995;7(10):2007-16.
1995: Bingren Hu; J Kurihara; Tadeusz Wieloch
Persistent translocation and inhibition of Ca2+/calmodulin-dependent protein kinase II in the crude synaptosomal fraction of the vulnerable hippocampus following hypoglycemia.
Journal of neurochemistry 1995;64(3):1361-9.
1995: Bingren Hu; Tadeusz Wieloch
Persistent translocation of Ca2+/calmodulin-dependent protein kinase II to synaptic junctions in the vulnerable hippocampal CA1 region following transient ischemia.
Journal of neurochemistry 1995;64(1):277-84.
1994: J Kurihara; Bingren Hu; Tadeusz Wieloch
Changes in the tyrosine phosphorylation of mitogen-activated protein kinase in the rat hippocampus during and following severe hypoglycemia.
Journal of neurochemistry 1994;63(6):2346-8.
1994: Bingren Hu; Tadeusz Wieloch
Tyrosine phosphorylation and activation of mitogen-activated protein kinase in the rat brain following transient cerebral ischemia.
Journal of neurochemistry 1994;62(4):1357-67.
1994: C Coimbra; Tadeusz Wieloch
Moderate hypothermia mitigates neuronal damage in the rat brain when initiated several hours following transient cerebral ischemia.
Acta neuropathologica 1994;87(4):325-31.
1993: Bingren Hu; Y B Yang; Tadeusz Wieloch
Depression of neuronal protein synthesis initiation by protein tyrosine kinase inhibitors.
Journal of neurochemistry 1993;61(5):1789-94.
1993: M Cardell; Tadeusz Wieloch
Time course of the translocation and inhibition of protein kinase C during complete cerebral ischemia in the rat.
Journal of neurochemistry 1993;61(4):1308-14.
1993: K Bergstedt; Tadeusz Wieloch
Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(5):895-8.
1993: Bingren Hu; Y B Yang; Tadeusz Wieloch
Heat-shock inhibits protein synthesis and eIF-2 activity in cultured cortical neurons.
Neurochemical research 1993;18(9):1003-7.
1993: Bingren Hu; Tadeusz Wieloch
Casein kinase II activity in the postischemic rat brain increases in brain regions resistant to ischemia and decreases in vulnerable areas.
Journal of neurochemistry 1993;60(5):1722-8.
1993: K Bergstedt; Bingren Hu; Tadeusz Wieloch
Postischaemic changes in protein synthesis in the rat brain: effects of hypothermia.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1993;95(1):91-9.
1993: Tadeusz Wieloch; K Bergstedt; Bingren Hu
Protein phosphorylation and the regulation of mRNA translation following cerebral ischemia.
Progress in brain research 1993;96():179-91.
1993: K Bergstedt; Bingren Hu; Tadeusz Wieloch
Initiation of protein synthesis and heat-shock protein-72 expression in the rat brain following severe insulin-induced hypoglycemia.
Acta neuropathologica 1993;86(2):145-53.
1992: C Coimbra; Tadeusz Wieloch
Hypothermia ameliorates neuronal survival when induced 2 hours after ischaemia in the rat.
Acta physiologica Scandinavica 1992;146(4):543-4.
1992: I Gustafson; E J Westerberg; Tadeusz Wieloch
Effects of ischemia on regional ligand binding to adrenoceptors in the rat brain.
Journal of the neurological sciences 1992;113(2):165-76.
1992: B Nellgård; Tadeusz Wieloch
NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain.
Acta physiologica Scandinavica 1992;146(4):497-503.
1992: J Deshpande; K Bergstedt; Thomas Lindén; H Kalimo; Tadeusz Wieloch
Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: evidence against programmed cell death.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1992;88(1):91-105.
1992: B Nellgård; Tadeusz Wieloch
Cerebral protection by AMPA- and NMDA-receptor antagonists administered after severe insulin-induced hypoglycemia.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1992;92(2):259-66.
1992: I Gustafson; A Lidén; Tadeusz Wieloch
Brain cortical tissue levels of noradrenaline and its glycol metabolites: effects of ischemia and postischemic administration of idazoxan.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1992;90(3):551-6.
1992: B Nellgård; Tadeusz Wieloch
Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(1):2-11.
1991: M Cardell; Fredrik Boris-Möller; Tadeusz Wieloch
Hypothermia prevents the ischemia-induced translocation and inhibition of protein kinase C in the rat striatum.
Journal of neurochemistry 1991;57(5):1814-7.
1991: B Nellgård; I Gustafson; Tadeusz Wieloch
Lack of protection by the N-methyl-D-aspartate receptor blocker dizocilpine (MK-801) after transient severe cerebral ischemia in the rat.
Anesthesiology 1991;75(2):279-287.
1991: Tadeusz Wieloch; M Cardell; H Bingren; J Zivin; T Saitoh
Changes in the activity of protein kinase C and the differential subcellular redistribution of its isozymes in the rat striatum during and following transient forebrain ischemia.
Journal of neurochemistry 1991;56(4):1227-35.
1991: M Cardell; Bo K Siesjö; Tadeusz Wieloch
Changes in pyruvate dehydrogenase complex activity during and following severe insulin-induced hypoglycemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1991;11(1):122-8.
1991: I Gustafson; E J Westerberg; Tadeusz Wieloch
Extracellular brain cortical levels of noradrenaline in ischemia: effects of desipramine and postischemic administration of idazoxan.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1991;86(3):555-61.
1990: M Cardell; H Bingren; Tadeusz Wieloch; J Zivin; T Saitoh
Protein kinase C is translocated to cell membranes during cerebral ischemia.
Neuroscience letters 1990;119(2):228-32.
1990: I Gustafson; E Westerberg; Tadeusz Wieloch
Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(6):885-94.
1990: J Lundgren; M Cardell; Tadeusz Wieloch; Bo K Siesjö
Preischemic hyperglycemia and postischemic alteration of rat brain pyruvate dehydrogenase activity.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(4):536-41.
1990: E Westerberg; K Magnusson; Tadeusz Wieloch; U Ungerstedt; Carmela Speciale; Robert Schwarcz
Extracellular levels of quinolinic acid are moderately increased in rat neostriatum following severe insulin-induced hypoglycaemia.
Acta physiologica Scandinavica 1990;138(3):417-22.
1990: Tadeusz Wieloch; Y Miyauchi; Olle Lindvall
Neuronal damage in the striatum following forebrain ischemia: lack of effect of selective lesions of mesostriatal dopamine neurons.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;83(1):159-63.
1989: Y Miyauchi; Tadeusz Wieloch; Olle Lindvall
Noradrenaline metabolism in neocortex and hippocampus following transient forebrain ischemia in rats: relation to development of selective neuronal necrosis.
Journal of neurochemistry 1989;53(2):408-15.
1989: E Westerberg; Tadeusz Wieloch
Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia.
Journal of neurochemistry 1989;52(5):1340-7.
1989: I Gustafson; Y Miyauchi; Tadeusz Wieloch
Postischemic administration of idazoxan, an alpha-2 adrenergic receptor antagonist, decreases neuronal damage in the rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(2):171-4.
1989: E Westerberg; D T Monaghan; H Kalimo; Carl W Cotman; Tadeusz Wieloch
Dynamic changes of excitatory amino acid receptors in the rat hippocampus following transient cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(3):798-805.
1989: K Magnusson; Tadeusz Wieloch
Impairment of protein ubiquitination may cause delayed neuronal death.
Neuroscience letters 1989;96(3):264-70.
1987: E Westerberg; D T Monaghan; Carl W Cotman; Tadeusz Wieloch
Excitatory amino acid receptors and ischemic brain damage in the rat.
Neuroscience letters 1987;73(2):119-24.