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Heinz Wiendl

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Luisa Klotz; Heinz Wiendl
Monoclonal antibodies in neuroinflammatory diseases.
Alexander Schwarz; Heinz Wiendl; Bettina Balint; Jürgen Haas; Sven Jarius; Daniel Pfaff; Kai Schumacher; Marijana Schumacher; Brigitte Wildemann
Fine-tuning of regulatory T cell function: the role of calcium signals and naive regulatory T cells for regulatory T cell deficiency in multiple sclerosis.
Ludwig Kappos; Paul W O'Connor; Amy Pace; Christopher H Polman; Patrick Vermersch; Heinz Wiendl; Annie Zhang; Christophe Hotermans
Clinical effects of natalizumab on multiple sclerosis appear early in treatment course.

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All Publications

2013: Luisa Klotz; Heinz Wiendl
Monoclonal antibodies in neuroinflammatory diseases.
Expert opinion on biological therapy 2013;13(6):831-46.
2013: Alexander Schwarz; Heinz Wiendl; Bettina Balint; Jürgen Haas; Sven Jarius; Daniel Pfaff; Kai Schumacher; Marijana Schumacher; Brigitte Wildemann
Fine-tuning of regulatory T cell function: the role of calcium signals and naive regulatory T cells for regulatory T cell deficiency in multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(10):4965-70.
2013: Ludwig Kappos; Paul W O'Connor; Amy Pace; Christopher H Polman; Patrick Vermersch; Heinz Wiendl; Annie Zhang; Christophe Hotermans
Clinical effects of natalizumab on multiple sclerosis appear early in treatment course.
Journal of neurology 2013;260(5):1388-95.
2013: Nico Melzer; Sven G Meuth; Heinz Wiendl
Paraneoplastic and non-paraneoplastic autoimmunity to neurons in the central nervous system.
Journal of neurology 2013;260(5):1215-33.
2013: Sven G Meuth; Johannes Müthing; Hermann Pavenstädt; Georg Peters; Martin A Ritter; Wolfram Schwindt; Wiebke Storck; Heinz Wiendl; Martina Bielaszewska; Thomas Budde; Philippe Coulon; Petra Ehling; Kerstin Göbel; Alexander M Herrmann; Tatyana Kanyshkova; Helge Karch; Denise Kohmann; Tanja Kuhlmann; Pia Lebiedz; Hans-Christian Pape
Thalamic involvement in patients with neurologic impairment due to Shiga toxin 2.
Annals of neurology 2013;73(3):419-29.
2013: Catharina C Gross; Heinz Wiendl
Dendritic cell vaccination in autoimmune disease.
Current opinion in rheumatology 2013;25(2):268-74.
2013: Heinz Wiendl; Bernd Kieseier
Multiple sclerosis: reprogramming the immune repertoire with alemtuzumab in MS.
Nature reviews. Neurology 2013;9(3):125-6.
2013: Benjamin M Greenberg; Eva Havrdova; Bernhard Hemmer; Bernd C Kieseier; Robert Lisak; Aaron Miller; Michael K Racke; Lawrence Steinman; Olaf Stuve; Heinz Wiendl; Laura J Balcer; Peter A Calabresi; Bruce A C Cree; Anne Cross; Teresa C Frohman; Ralf Gold; Elliot Frohman
Interferon beta use and disability prevention in relapsing-remitting multiple sclerosis.
JAMA neurology 2013;70(2):248-51.
2013: Joseph Andronic; Stefan Bittner; Nicole Bobak; Thomas Budde; Petra Ehling; Alexander M Herrmann; Christoph Kleinschnitz; Sven G Meuth; Markus Sauer; Heinz Wiendl; Heiko Zimmermann; Vladimir Sukhorukov
Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes.
Biochimica et biophysica acta 2013;1828(2):699-707.
2013: Christoph Kleinschnitz; Peter Kraft; Friederike Langhauser; Tim Magnus; Christian T Mayer; Sven G Meuth; Bernhard Nieswandt; Mirko Pham; Michael K Schuhmann; Tobias Schwarz; Tim D. Sparwasser; Guido Stoll; Csanad Varallyay; Martin Bendszus; Stefan Bittner; Marc Brede; Angela Dreykluft; Kerstin Göbel; Ina Hagedorn; Xavier Helluy; Yoichiro Iwakura; Peter Jakob; Alma Zernecke; Heinz Wiendl
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Blood 2013;121(4):679-91.
2013: Petra Ehling; Christoph Kleinschnitz; Stefan Bittner; Nicole Bobak; Thomas Budde; Tobias Schwarz; Heinz Wiendl; Sven G Meuth
Correction: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9).
Experimental & translational stroke medicine 2013;5(1):3.
2012: Stefan Bittner; Nicole Bobak; Johanna Breuer; Thomas Budde; Petra Ehling; Melina Golfels; Alexander M Herrmann; Marcella A Bauer; Heinz Wiendl; Sven G Meuth
The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis.
Experimental neurology 2012;238(2):149-55.
2012: Nir Yogev; Heinz Wiendl; Tal Birnberg; Thomas Blank; Friederike Frommer; Daniele Ielo; Steffen Jung; Khalad Karram; Kordula Kautz-Neu; Thomas Korn; Florian C Kurschus; Dominika Lukas; Marco Prinz; Hans-Christian Probst; Boris Reizis; Dieter Riethmacher; Maries van den Broek; Esther Von Stebut; Ari Waisman
Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells.
Immunity 2012;37(2):264-75.
2012: Clemens Warnke; Heinz Wiendl; Helena C Kronsbein; Volker Limmroth; Mathias Mäurer; Anita Posevitz-Fejfár; Stephan Schmidt; Florian Seitz; Björn Tackenberg; Ortwin Adams; Achim Berthele; Andrew Chan; Thomas Dehmel; Kathrin Gerbershagen; Ralf Gold; Judith Haas; Hans-Peter Hartung; Bernhard Hemmer; Bernd C Kieseier
Anti-JC-virus antibody prevalence in a German MS cohort.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(7):1054-5.
2012: Tim Magnus; Heinz Wiendl; Christoph Kleinschnitz
Immune mechanisms of stroke.
Current opinion in neurology 2012;25(3):334-40.
2012: Heinz Wiendl
Neuroinflammation: the world is not enough.
Current opinion in neurology 2012;25(3):302-5.
2012: Nico Melzer; Sven G Meuth; Heinz Wiendl
Neuron-directed autoimmunity in the central nervous system: entities, mechanisms, diagnostic clues, and therapeutic options.
Current opinion in neurology 2012;25(3):341-8.
2012: Nico Melzer; Sven G Meuth; Thomas Niederstadt; Walter Stummer; Oliver Martin Grauer; Catharina C Gross; Anja Harder; Martin Marziniak; Johannes Wölfer; Heinz Wiendl
CD4(+) T cells predominate in cerebrospinal fluid and leptomeningeal and parenchymal infiltrates in cerebral amyloid β-related angiitis.
Archives of neurology 2012;69(6):773-7.
2012: Nico Melzer; Klaus-Michael Müller; Matthias Schilling; Peter Josef Barth; Hans-Dieter Foss; Oliver Martin Grauer; Utz Krug; Martin Marziniak; Heinz Wiendl
Rapidly progressive B-cell dominated inflammatory neuropathy and littoral cell angioma of the spleen associated with plasmablastic B-cell lymphoma.
Leukemia & lymphoma 2012;53(6):1242-4.
2012: A K Trampe; Heinz Wiendl; Andreas Ziegler; S Goelz; R Gold; Arash Haghikia; Kerstin Hellwig; Claudia Hemmelmann; A Stroet; A Chan
Anti-JC virus antibodies in a large German natalizumab-treated multiple sclerosis cohort.
Neurology 2012;78(22):1736-42.
2012: Stephanie Hucke; Johannes Jungverdorben; Thomas Klockgether; Oliver Brüstle; Ildiko R Dunay; Juliane Floßdorf; Kathrin Frenzel; Berit Grützke; Percy Knolle; Christian Kurts; Bettina Linnartz; Matthias Mack; Harald Neumann; Michael Peitz; Marco Prinz; Heinz Wiendl; Luisa Klotz
Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.
Brain : a journal of neurology 2012;135(Pt 5):1586-605.
2012: Catharina C Gross; Helmut Jonuleit; Heinz Wiendl
Fulfilling the dream: tolerogenic dendritic cells to treat multiple sclerosis.
European journal of immunology 2012;42(3):569-72.
2012: Nicholas Schwab; Max-Philipp Stenner; Wolfgang Brück; Renaud A Du Pasquier; Ralf Gold; Karin G Höhn; Samantha Jilek; Imke Metz; Sven G Meuth; Richard M Ransohoff; Tilman Schneider-Hohendorf; Heinz Wiendl
Immunological and clinical consequences of treating a patient with natalizumab.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(3):335-44.
2012: Imke Metz; Agustin Oterino; Ernst-Wilhelm Radue; Mohammad Ali Sahraian; Sven Schippling; Heinz Wiendl; Francoise Gray; Darius Häusler; Veronika Jakl; Jens Kuhle; Tania Kümpfel; Wolfgang Brück
Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy.
Acta neuropathologica 2012;123(2):235-45.
2012: Nico Melzer; Sven G Meuth; Kristin S Golombeck; Catharina C Gross; Heinz Wiendl
Cytotoxic CD8+ T cells and CD138+ plasma cells prevail in cerebrospinal fluid in non-paraneoplastic cerebellar ataxia with contactin-associated protein-2 antibodies.
Journal of neuroinflammation 2012;9():160.
2012: Sven G Meuth; Kerstin Göbel; Heinz Wiendl
Immune therapy of multiple sclerosis--future strategies.
Current pharmaceutical design 2012;18(29):4489-97.
2012: Kerstin Göbel; Nico Melzer; Sven G Meuth; Susann Pankratz; Michael K Schuhmann; Stefan Bittner; Angela Dreykluft; Heinz Wiendl
CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level.
Journal of neuroinflammation 2012;9():41.
2012: Luisa Klotz; Sven G Meuth; Heinz Wiendl
Immune mechanisms of new therapeutic strategies in multiple sclerosis-A focus on alemtuzumab.
Clinical immunology (Orlando, Fla.) 2012;142(1):25-30.
2011: Petra Ehling; Stefan Bittner; Thomas Budde; Heinz Wiendl; Sven G Meuth
Ion channels in autoimmune neurodegeneration.
FEBS letters 2011;585(23):3836-42.
2011: L Klotz; T Korn; F Zipp; R Gold; B Hemmer; R Hohlfeld; Bernd C Kieseier; Heinz Wiendl
[Diagnosis of multiple sclerosis 2010 revision of the McDonald criteria].
Der Nervenarzt 2011;82(10):1302-9.
2011: C Warnke; Heinz Wiendl; F Zipp; M Stangel; Ortwin Adams; Ralf Gold; Hans-Peter Hartung; Bernhard Hemmer; R Hohlfeld; Bernd C Kieseier
[Risk stratification of progressive multifocal leukoencephalopathy under natalizumab: recommendations for JC virus serology].
Der Nervenarzt 2011;82(10):1314-9.
2011: A Waschbisch; H-P Hartung; L Kappos; C Pohl; R Sandbrink; Stefan Schwab; Heinz Wiendl
Evaluation of soluble HLA-G as a biomarker for multiple sclerosis.
Neurology 2011;77(6):596-8.
2011: Nicole Bobak; Thomas Budde; Frank Döring; Kerstin Göbel; Susanne Hartmann; Patrick Meuth; Sven G Meuth; Friederike Mühlpfordt; Carsten Schmelter; Tilman Schneider-Hohendorf; Heinz Wiendl; Erhard Wischmeyer; Karen Wolf; Heiko Zimmermann; Joseph Andronic; Stefan Bittner; Vladimir Sukhorukov
Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels.
Biochimica et biophysica acta 2011;1808(8):2036-44.
2011: Bernd C Kieseier; Heinz Wiendl
Transforming multiple sclerosis trials into practical reality.
Lancet neurology 2011;10(6):493-4.
2011: Bernd C Kieseier; Heinz Wiendl; Hans-Peter Hartung; Verena-Isabell Leussink; Olaf Stüve
Risks and benefits of multiple sclerosis therapies: need for continual assessment?
Current opinion in neurology 2011;24(3):238-43.
2011: João Carlos Correia de Sa; Nikolaos Grigoriadis; Laura Airas; Emmanuel Bartholome; Heinrich Mattle; Celia Oreja-Guevara; Jonathan O'Riordan; Finn Sellebjerg; Bruno Stankoff; Karl Vass; Agata Walczak; Heinz Wiendl; Bernd C Kieseier
Symptomatic therapy in multiple sclerosis: a review for a multimodal approach in clinical practice.
Therapeutic advances in neurological disorders 2011;4(3):139-68.
2011: C Warnke; Ortwin Adams; Ralf Gold; Hans-Peter Hartung; R Hohlfeld; Heinz Wiendl; Bernd C Kieseier
[Progressive multifocal leukoencephalopathy under natalizumab. Initial possibilities for risk stratification?].
Der Nervenarzt 2011;82(4):475-80.
2011: Kerstin Göbel; Stefan Bittner; Tobias Ruck; Thomas Budde; Erhard Wischmeyer; Frank Döring; Heinz Wiendl; Sven G Meuth
Active immunization with proteolipid protein (190-209) induces ascending paralysing experimental autoimmune encephalomyelitis in C3H/HeJ mice.
Journal of immunological methods 2011;367(1-2):27-32.
2011: Kerstin Göbel; Susann Pankratz; Tilman Schneider-Hohendorf; Stefan Bittner; Michael K Schuhmann; Harald F Langer; Guido Stoll; Heinz Wiendl; Christoph Kleinschnitz; Sven G Meuth
Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking.
Journal of autoimmunity 2011;36(2):106-14.
2011: Sven G Meuth; Stefan Bittner; Carola Seiler; Kerstin Göbel; Heinz Wiendl
Natalizumab restores evoked potential abnormalities in patients with relapsing-remitting multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(2):198-203.
2011: Yu-Hwa Huang; Laura Airas; Nicholas Schwab; Heinz Wiendl
Janus head: the dual role of HLA-G in CNS immunity.
Cellular and molecular life sciences : CMLS 2011;68(3):407-16.
2011: Clemens Warnke; Vsevolod Smolianov; Thomas Dehmel; Marcel Andrée; Hartmut Hengel; Fabian Zohren; Gabriele Arendt; Heinz Wiendl; Rainer Haas; Hans-Peter Hartung; Ortwin Adams; Bernd C Kieseier
CD34+ progenitor cells mobilized by natalizumab are not a relevant reservoir for JC virus.
Multiple sclerosis (Houndmills, Basingstoke, England) 2011;17(2):151-6.
2011: Arash Haghikia; Moritz Perrech; Bartosz Pula; Sabrina Ruhrmann; Anja Potthoff; Norbert H Brockmeyer; Susan Goelz; Heinz Wiendl; Hans Lindå; Tjalf Ziemssen; Sergio E Baranzini; Tor-Björn Käll; Dietmar Bengel; Tomas Olsson; Ralf Gold; Andrew Chan
Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders.
PloS one 2011;6(4):e18506.
2011: Stefan Bittner; Nicole Bobak; Thomas Budde; Martin Feuchtenberger; Oliver Frey; Kerstin Göbel; Anker J Hansen; Alexander M Herrmann; Raimund W Kinne; Christoph Kleinschnitz; Hans-Peter Tony; Heinz Wiendl; Sven G Meuth
Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients.
Arthritis research & therapy 2011;13(1):R21.
2010: Tilman Schneider-Hohendorf; Max-Philipp Stenner; Christian Weidenfeller; Alla L Zozulya; Ole J Simon; Nicholas Schwab; Heinz Wiendl
Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis.
European journal of immunology 2010;40(12):3581-90.
2010: Alexander M Herrmann; Kerstin Göbel; Ole J Simon; Nico Melzer; Michael K Schuhmann; Max-Philipp Stenner; Andreas Weishaupt; Christoph Kleinschnitz; Stefan Bittner; Patrick Meuth; Olaf Stuve; Thomas Budde; Bernd C Kieseier; Heinz Wiendl; Sven G Meuth
Glatiramer acetate attenuates pro-inflammatory T cell responses but does not directly protect neurons from inflammatory cell death.
The American journal of pathology 2010;177(6):3051-60.
2010: Stefan Bittner; Thomas Budde; Heinz Wiendl; Sven G Meuth
From the background to the spotlight: TASK channels in pathological conditions.
Brain pathology (Zurich, Switzerland) 2010;20(6):999-1009.
2010: Sven G Meuth; Stefan Bittner; Jochen C Ulzheimer; Christoph Kleinschnitz; Bernd C Kieseier; Heinz Wiendl
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2010;24(5):317-30.
2010: Anne Waschbisch; Nicholas Schwab; Tobias Ruck; Max-Philipp Stenner; Heinz Wiendl
FOXP3+ T regulatory cells in idiopathic inflammatory myopathies.
Journal of neuroimmunology 2010;225(1-2):137-42.
2010: Bernd C Kieseier; Heinz Wiendl
Postpartum disease activity and breastfeeding in multiple sclerosis revisited.
Neurology 2010;75(5):392-3.
2010: Jochen C Ulzheimer; Sven G Meuth; Stefan Bittner; Christoph Kleinschnitz; Bernd C Kieseier; Heinz Wiendl
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of immunomodulatory treatment strategies.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2010;24(4):249-74.
2010: Claudia Heidbrink; Sebastian F M Häusler; Mathias Buttmann; Monika Ossadnik; Herwig M Strik; Andreas Keller; Dorothea Buck; Evert Verbraak; Marjan van Meurs; Mathias Krockenberger; Matthias Mehling; Michel Mittelbronn; Jon D Laman; Heinz Wiendl; Jörg Wischhusen
Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11beta-hydroxysteroid dehydrogenases in multiple sclerosis: implications for lesion pathogenesis.
Brain, behavior, and immunity 2010;24(6):975-84.
2010: Christian Wolf; Til Menge; Max-Philipp Stenner; Gerd Meyer zu Hörste; Andreas Saleh; Hans-Peter Hartung; Heinz Wiendl; Bernd C Kieseier
Natalizumab treatment in a patient with chronic inflammatory demyelinating polyneuropathy.
Archives of neurology 2010;67(7):881-3.
2010: Stefan Bittner; Nicole Bobak; Alexander M Herrmann; Kerstin Göbel; Patrick Meuth; Karin G Höhn; Max-Philipp Stenner; Thomas Budde; Heinz Wiendl; Sven G Meuth
Upregulation of K2P5.1 potassium channels in multiple sclerosis.
Annals of neurology 2010;68(1):58-69.
2010: Mathias Buttmann; Heinz Wiendl
[Therapeutic monoclonal antibodies in clinical neurology].
Der Nervenarzt 2010;81(6):753-64; quiz 765-6.
2010: Alla L Zozulya; Benjamin D Clarkson; Sonja Ortler; Zsuzsanna Fabry; Heinz Wiendl
The role of dendritic cells in CNS autoimmunity.
Journal of molecular medicine (Berlin, Germany) 2010;88(6):535-44.
2010: Christoph Kleinschnitz; Nicholas Schwab; Peter Kraft; Ina Hagedorn; Angela Dreykluft; Tobias Schwarz; Madeleine Austinat; Bernhard Nieswandt; Heinz Wiendl; Guido Stoll
Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation.
Blood 2010;115(18):3835-42.
2010: Ingo Kleiter; Jian Song; Dominika Lukas; Maruf Hasan; Bernhard Neumann; Andrew L Croxford; Xiomara Pedré; Nadine Hövelmeyer; Nir Yogev; Alexander Mildner; Marco Prinz; Elena Wiese; Kurt Reifenberg; Stefan Bittner; Heinz Wiendl; Lawrence Steinman; Christoph Becker; Ulrich Bogdahn; Markus F Neurath; Andreas Steinbrecher; Ari Waisman
Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis.
Brain : a journal of neurology 2010;133(Pt 4):1067-81.
2010: Bianca Kohl; Janos Groh; Carsten Wessig; Heinz Wiendl; Antje Kroner; Rudolf Martini
Lack of evidence for a pathogenic role of T-lymphocytes in an animal model for Charcot-Marie-Tooth disease 1A.
Neurobiology of disease 2010;38(1):78-84.
2010: Gerd Meyer Zu Hörste; Alla L Zozulya; Houda El-Haddad; Helmar C Lehmann; Hans-Peter Hartung; Heinz Wiendl; Bernd C Kieseier
Active immunization induces toxicity of diphtheria toxin in diphtheria resistant mice--implications for neuroinflammatory models.
Journal of immunological methods 2010;354(1-2):80-4.
2010: Nurcan Üçeyler; Kerstin Göbel; Sven G Meuth; Sonja Ortler; Guido Stoll; Claudia Sommer; Heinz Wiendl; Christoph Kleinschnitz
Deficiency of the negative immune regulator B7-H1 enhances inflammation and neuropathic pain after chronic constriction injury of mouse sciatic nerve.
Experimental neurology 2010;222(1):153-60.
2010: Kerstin Göbel; Nico Melzer; Alexander M Herrmann; Michael K Schuhmann; Stefan Bittner; Chi Wang Ip; Thomas Hünig; Sven G Meuth; Heinz Wiendl
Collateral neuronal apoptosis in CNS gray matter during an oligodendrocyte-directed CD8(+) T cell attack.
Glia 2010;58(4):469-80.
2010: Michael K Schuhmann; David Stegner; Alejandro Berna-Erro; Stefan Bittner; Attila Braun; Christoph Kleinschnitz; Guido Stoll; Heinz Wiendl; Sven G Meuth; Bernhard Nieswandt
Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1536-42.
2010: Gerd Meyer zu Hörste; Holger Heidenreich; Anne K Mausberg; Helmar C Lehmann; Anneloor L M A ten Asbroek; José T Saavedra; Frank Baas; Hans-Peter Hartung; Heinz Wiendl; Bernd C Kieseier
Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation.
Neurobiology of disease 2010;37(2):483-90.
2010: Sebastian Doerck; Kerstin Göbel; Gesa Weise; Tilman Schneider-Hohendorf; Michael Reinhardt; Peter Hauff; Nicholas Schwab; Ralf A Linker; Mathias Mäurer; Sven G Meuth; Heinz Wiendl
Temporal pattern of ICAM-I mediated regulatory T cell recruitment to sites of inflammation in adoptive transfer model of multiple sclerosis.
PloS one 2010;5(11):e15478.
2010: Clemens Warnke; Heinz Wiendl; Hans-Peter Hartung; Olaf Stüve; Bernd C Kieseier
Identification of targets and new developments in the treatment of multiple sclerosis--focus on cladribine.
Drug design, development and therapy 2010;4():117-26.
2010: Petra Ehling; Stefan Bittner; Nicole Bobak; Tobias Schwarz; Heinz Wiendl; Thomas Budde; Christoph Kleinschnitz; Sven G Meuth
Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9).
Experimental & translational stroke medicine 2010;2(1):14.
2010: Carolin Brandl; Sonja Ortler; Thomas Herrmann; Susanna Cardell; Manfred B Lutz; Heinz Wiendl
B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells.
PloS one 2010;5(5):e10800.
2010: Gerd Meyer Zu Horste; Holger Heidenreich; Helmar C Lehmann; Soldano Ferrone; Hans-Peter Hartung; Heinz Wiendl; Bernd C Kieseier
Expression of antigen processing and presenting molecules by Schwann cells in inflammatory neuropathies.
Glia 2010;58(1):80-92.
2009: Sven G Meuth; Alexander M Herrmann; Ole J Simon; Volker Siffrin; Nico Melzer; Stefan Bittner; Patrick Meuth; Harald F Langer; Stefan Hallermann; Nadia Boldakowa; Josephine Herz; Thomas Munsch; Peter Landgraf; Orhan Aktas; Manfred Heckmann; Volkmar Lessmann; Thomas Budde; Bernd C Kieseier; Frauke Zipp; Heinz Wiendl
Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(49):15397-409.
2009: Thomas Dörner; David Isenberg; David Jayne; Heinz Wiendl; Detlef Zillikens; Gerd Burmester
Current status on B-cell depletion therapy in autoimmune diseases other than rheumatoid arthritis.
Autoimmunity reviews 2009;9(2):82-9.
2009: Nico Melzer; Sven G Meuth; Heinz Wiendl
CD8+ T cells and neuronal damage: direct and collateral mechanisms of cytotoxicity and impaired electrical excitability.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(11):3659-73.
2009: Olaf Stüve; Heinz Wiendl
Iatrogenic immunosuppression with biologics in MS: expecting the unexpected?
Neurology 2009;73(17):1346-7.
2009: Bernd C Kieseier; Heinz Wiendl; Hans-Peter Hartung; Olaf Stüve
The future of multiple sclerosis therapy.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;60(4):207-11.
2009: Til Menge; Nanette C Schloot; M Schott; Bernhard Hemmer; Heinz Wiendl; M Roden; Hans-Peter Hartung; Bernd C Kieseier
Interferon beta treatment does not induce organ-specific autoantibodies in multiple sclerosis.
Neurology 2009;73(11):900-2.
2009: Bettina Sobottka; Melanie Denise Harrer; Urs Ziegler; Katja Fischer; Heinz Wiendl; Thomas Hünig; Burkhard Becher; Norbert Goebels
Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss.
The American journal of pathology 2009;175(3):1160-6.
2009: Stefan Bittner; Sven G Meuth; Kerstin Göbel; Nico Melzer; Alexander M Herrmann; Ole J Simon; Andreas Weishaupt; Thomas Budde; Douglas A Bayliss; Martin Bendszus; Heinz Wiendl
TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system.
Brain : a journal of neurology 2009;132(Pt 9):2501-16.
2009: Stefan Bittner; Heinz Wiendl; Sven G Meuth
Comment on "Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse".
Immunology letters 2009;125(2):156-7.
2009: Yu-Hwa Huang; Alla L Zozulya; Christian Weidenfeller; Imke Metz; Dorothea Buck; Klaus V Toyka; Wolfgang Brück; Heinz Wiendl
Specific central nervous system recruitment of HLA-G(+) regulatory T cells in multiple sclerosis.
Annals of neurology 2009;66(2):171-83.
2009: Yu-Hwa Huang; Alla L Zozulya; Christian Weidenfeller; Nicholas Schwab; Heinz Wiendl
T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible.
Journal of leukocyte biology 2009;86(2):273-81.
2009: Antje Kroner; Nicholas Schwab; Chi Wang Ip; Sonja Ortler; Kerstin Göbel; Klaus-Armin Nave; Mathias Mäurer; Rudolf Martini; Heinz Wiendl
Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants.
The American journal of pathology 2009;174(6):2290-9.
2009: Alla L Zozulya; Sonja Ortler; Zsuzsanna Fabry; Matyas Sandor; Heinz Wiendl
The level of B7 homologue 1 expression on brain DC is decisive for CD8 Treg cell recruitment into the CNS during EAE.
European journal of immunology 2009;39(6):1536-43.
2009: Shin-Young Na; Heike Eujen; Kerstin Göbel; Sven G Meuth; Kati Martens; Heinz Wiendl; Thomas Hünig
Antigen-specific blockade of lethal CD8 T-cell mediated autoimmunity in a mouse model of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6569-75.
2009: Nicholas Schwab; Christian G Bien; Anne Waschbisch; Albert Becker; Giles H Vince; Klaus Dornmair; Heinz Wiendl
CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery.
Brain : a journal of neurology 2009;132(Pt 5):1236-46.
2009: Anne Waschbisch; Sven G Meuth; Alexander M Herrmann; Barbara Wrobel; Nicholas Schwab; Hanns Lochmüller; Heinz Wiendl
Intercellular exchanges of membrane fragments (trogocytosis) between human muscle cells and immune cells: a potential mechanism for the modulation of muscular immune responses.
Journal of neuroimmunology 2009;209(1-2):131-8.
2009: Heinz Wiendl; Reinhard Hohlfeld
Multiple sclerosis therapeutics: unexpected outcomes clouding undisputed successes.
Neurology 2009;72(11):1008-15.
2009: Alla L Zozulya; Sonja Ortler; JangEun Lee; Christian Weidenfeller; Matyas Sandor; Heinz Wiendl; Zsuzsanna Fabry
Intracerebral dendritic cells critically modulate encephalitogenic versus regulatory immune responses in the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(1):140-52.
2009: Antje Kroner; Nicholas Schwab; Chi Wang Ip; Christoph Leder; Klaus-Armin Nave; Mathias Mäurer; Heinz Wiendl; Rudolf Martini
PD-1 regulates neural damage in oligodendroglia-induced inflammation.
PloS one 2009;4(2):e4405.
2008: Sven G Meuth; Tatjana Kanyshkov; Nico Melzer; Stefan Bittner; Bernd C Kieseier; Thomas Budde; Heinz Wiendl
Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation.
Neuroscience letters 2008;446(2-3):133-8.
2008: Sven G Meuth; Christoph Kleinschnitz; Heinz Wiendl
Recent clinical trials and future therapies.
Journal of neurology 2008;255 Suppl 6():93-6.
2008: Bernd C Kieseier; Heinz Wiendl; Verena I Leussink; Olaf Stüve
Immunomodulatory treatment strategies in multiple sclerosis.
Journal of neurology 2008;255 Suppl 6():15-21.
2008: Anne Waschbisch; Sabine Wintterle; Hanns Lochmüller; Maggie C Walter; Jörg Wischhusen; Bernd C Kieseier; Heinz Wiendl
Human muscle cells express the costimulatory molecule B7-H3, which modulates muscle-immune interactions.
Arthritis and rheumatism 2008;58(11):3600-8.
2008: Alla L Zozulya; Heinz Wiendl
The role of CD8 suppressors versus destructors in autoimmune central nervous system inflammation.
Human immunology 2008;69(11):797-804.
2008: Heinz Wiendl
Idiopathic inflammatory myopathies: current and future therapeutic options.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2008;5(4):548-57.
2008: Nicholas Schwab; Anne Waschbisch; Barbara Wrobel; Hanns Lochmüller; Claudia Sommer; Heinz Wiendl
Human myoblasts modulate the function of antigen-presenting cells.
Journal of neuroimmunology 2008;200(1-2):62-70.
2008: Thomas Dehmel; Hans-Hilmar Goebel; Hans-Peter Hartung; Helmar Lehmann; Heinz Wiendl; Bernd C Kieseier
The metalloproteinase-disintegrin ADAM10 is exclusively expressed by type I muscle fibers.
Muscle & nerve 2008;38(2):1049-51.
2008: Alla L Zozulya; Heinz Wiendl
The role of regulatory T cells in multiple sclerosis.
Nature clinical practice. Neurology 2008;4(7):384-98.
2008: Christian Kneitz; Heinz Wiendl
[Progressive multifocal leukoencephalopathy and rheumatic disease].
Zeitschrift für Rheumatologie 2008;67(4):290, 292-4.
2008: Marie-Edith Lafon; Françoise Mégret; Sven G Meuth; Ole Simon; Myriam L Velandia Romero; Mireille Lafage; Lieping Chen; Lena Alexopoulou; Richard A Flavell; Christophe Prehaud; Heinz Wiendl
Detrimental contribution of the immuno-inhibitor B7-H1 to rabies virus encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7506-15.
2008: Sonja Ortler; Christoph Leder; Michel Mittelbronn; Alla L Zozulya; Percy A Knolle; Lieping Chen; Antje Kroner; Heinz Wiendl
B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis.
European journal of immunology 2008;38(6):1734-44.
2008: Sven G Meuth; Stefan Bittner; Patrick Meuth; Ole J Simon; Thomas Budde; Heinz Wiendl
TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions.
The Journal of biological chemistry 2008;283(21):14559-70.
2008: Sven G Meuth; Alexander M Herrmann; Chi W Ip; Tatyana Kanyshkova; Stefan Bittner; Andreas Weishaupt; Thomas Budde; Heinz Wiendl
The two-pore domain potassium channel TASK3 functionally impacts glioma cell death.
Journal of neuro-oncology 2008;87(3):263-70.
2008: Sven G Meuth; Ole J Simon; Alexander Grimm; Nico Melzer; Alexander M Herrmann; Philipp Spitzer; Peter Landgraf; Heinz Wiendl
CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing.
Journal of neuroimmunology 2008;194(1-2):62-9.
2008: Laura Airas; Maija Saraste; S Rinta; Irina Elovaara; Yu-Hwa Huang; Heinz Wiendl
Immunoregulatory factors in multiple sclerosis patients during and after pregnancy: relevance of natural killer cells.
Clinical and experimental immunology 2008;151(2):235-43.
2008: Martin Feuchtenberger; Sabine Müller; Petra Roll; Anne Waschbisch; Arne Schäfer; Christian Kneitz; Heinz Wiendl; Hans-Peter Tony
Frequency of regulatory T cells is not affected by transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis.
The open rheumatology journal 2008;2():81-8.
2008: Max-Philipp Stenner; Anne Waschbisch; Dorothea Buck; Sebastian Doerck; Hermann Einsele; Klaus V Toyka; Heinz Wiendl
Effects of natalizumab treatment on Foxp3+ T regulatory cells.
PloS one 2008;3(10):e3319.
2008: Nico Melzer; Sven G Meuth; Delany Torres-Salazar; Stefan Bittner; Alla L Zozulya; Christian Weidenfeller; Alexandra Kotsiari; Martin Stangel; Christoph Fahlke; Heinz Wiendl
A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis.
PloS one 2008;3(9):e3149.
2008: Olaf Stüve; Jeffrey Bennett; Bernhard Hemmer; Heinz Wiendl; Michael K Racke; Amit Bar-Or; Wei Hu; Robert Zivadinov; Martin S Weber; Scott S Zamvil; Maria F Pacheco; Til Menge; Hans-Peter Hartung; Bernd C Kieseier; Elliot M Frohman
Pharmacological treatment of early multiple sclerosis.
Drugs 2008;68(1):73-83.
2007: Jörg Wischhusen; Anne Waschbisch; Heinz Wiendl
Immune-refractory cancers and their little helpers--an extended role for immunetolerogenic MHC molecules HLA-G and HLA-E?
Seminars in cancer biology 2007;17(6):459-68.
2007: Christoph Kleinschnitz; Sven G Meuth; Olaf Stüve; Bernd C Kieseier; Heinz Wiendl
Multiple sclerosis therapy: an update on recently finished trials.
Journal of neurology 2007;254(11):1473-90.
2007: Christoph Leder; N Schwab; Chi Wang Ip; Antje Kroner; Klaus-Armin Nave; Klaus Dornmair; Rudolf Martini; Heinz Wiendl
Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice.
Molecular and cellular neurosciences 2007;36(3):416-24.
2007: T Kopadze; Thomas Dehmel; Heidrun A Mylius; Hans-Peter Hartung; Heinz Wiendl; Bernd C Kieseier
Treosulfan impedes the migration of immunocompetent cells.
Journal of neurology 2007;254(10):1457-8.
2007: Christoph Leder; Sonja Ortler; Ruth Seggewiss; Hermann Einsele; Heinz Wiendl
Modulation of T-effector function by imatinib at the level of cytokine secretion.
Experimental hematology 2007;35(8):1266-71.
2007: Christoph Kleinschnitz; Sven G Meuth; Bernd C Kieseier; Heinz Wiendl
[Update on pathophysiologic and immunotherapeutic approaches for the treatment of multiple sclerosis].
Der Nervenarzt 2007;78(8):883-911.
2007: Matthias Mehling; Perikles Simon; Michel Mittelbronn; Richard Meyermann; Soldano Ferrone; Michael Weller; Heinz Wiendl
WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism?
Acta neuropathologica 2007;114(2):111-9.
2007: Ute Feger; Eva Tolosa; Yu-Hwa Huang; Anne Waschbisch; Tilo Biedermann; Arthur Melms; Heinz Wiendl
HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation.
Blood 2007;110(2):568-77.
2007: Laura Airas; Tuomas Nikula; Yu-Hwa Huang; Riitta Lahesmaa; Heinz Wiendl
Postpartum-activation of multiple sclerosis is associated with down-regulation of tolerogenic HLA-G.
Journal of neuroimmunology 2007;187(1-2):205-11.
2007: Heinz Wiendl; Bernd C Kieseier; Robert Weissert; Heidrun A Mylius; Uwe Pichlmeier; Hans-Peter Hartung; Arthur Melms; Wilhelm Kuker; Michael Weller
Treatment of active secondary progressive multiple sclerosis with treosulfan.
Journal of neurology 2007;254(7):884-9.
2007: Bernd C Kieseier; Heinz Wiendl; Bernhard Hemmer; Hans-Peter Hartung
Treatment and treatment trials in multiple sclerosis.
Current opinion in neurology 2007;20(3):286-93.
2007: Antje Kroner; Alexander Grimm; Kirsten Johannssen; Mathias Mäurer; Heinz Wiendl
The genetic influence of the nonclassical MHC molecule HLA-G on multiple sclerosis.
Human immunology 2007;68(5):422-5.
2007: Heinz Wiendl
HLA-G in the nervous system.
Human immunology 2007;68(4):286-93.
2007: Christoph Kleinschnitz; Sven G Meuth; Bernd C Kieseier; Heinz Wiendl
Immunotherapeutic approaches in MS: update on pathophysiology and emerging agents or strategies 2006.
Endocrine, metabolic & immune disorders drug targets 2007;7(1):35-63.
2007: Ute Feger; Claudia Luther; Simone Poeschel; Arthur Melms; Eva Tolosa; Heinz Wiendl
Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients.
Clinical and experimental immunology 2007;147(3):412-8.
2007: Thomas Dehmel; Angela Janke; Hans-Peter Hartung; Hans-Hilmar Goebel; Heinz Wiendl; Bernd C Kieseier
The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies.
Neurobiology of disease 2007;25(3):665-74.
2007: Wei Hu; A Janke; S Ortler; Hans-Peter Hartung; Christoph Leder; Bernd C Kieseier; Heinz Wiendl
Expression of CD28-related costimulatory molecule and its ligand in inflammatory neuropathies.
Neurology 2007;68(4):277-82.
2007: Bernd C Kieseier; Heinz Wiendl
Oral disease-modifying treatments for multiple sclerosis: the story so far.
CNS drugs 2007;21(6):483-502.
2006: D Buck; Antje Kroner; Peter Rieckmann; Mathias Mäurer; Heinz Wiendl
Analysis of the C/T(-1) single nucleotide polymorphism in the CD40 gene in multiple sclerosis.
Tissue antigens 2006;68(4):335-8.
2006: Bernd C Kieseier; Hans-Peter Hartung; Heinz Wiendl
Immune circuitry in the peripheral nervous system.
Current opinion in neurology 2006;19(5):437-45.
2006: Bernd C Kieseier; Heinz Wiendl; Hans-Peter Hartung
The inflamed peripheral nervous system: update on immune therapies.
Current opinion in neurology 2006;19(5):433-6.
2006: Heinz Wiendl; Bernd C Kieseier; Ralf Gold; R Hohlfeld; M Bendszus; Hans-Peter Hartung
[Revision of McDonald's new diagnostic criteria for multiple sclerosis].
Der Nervenarzt 2006;77(10):1235, 1237-45.
2006: Riccardo Cassiani Ingoni; Turhan Coksaygan; Haipeng Xue; Susan Reichert-Scrivner; Heinz Wiendl; Mahendra S Rao; Tim Magnus
Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation.
Experimental neurology 2006;201(2):349-58.
2006: Chi Wang Ip; Antje Kroner; Martin Bendszus; Christoph Leder; Igor Kobsar; Stefan Fischer; Heinz Wiendl; Klaus-Armin Nave; Rudolf Martini
Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(31):8206-16.
2006: Christian Blank; Jürgen Kuball; Simon Voelkl; Heinz Wiendl; Bernd Becker; Bernhard Walter; Otto Majdic; Thomas F Gajewski; Matthias Theobald; Reinhard Andreesen; Andreas Mackensen
Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro.
International journal of cancer. Journal international du cancer 2006;119(2):317-27.
2006: Helmut R Salih; Sabine Wintterle; Matthias Krusch; Antje Kroner; Yu-Hwa Huang; Lieping Chen; Heinz Wiendl
The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans.
Experimental hematology 2006;34(7):888-94.
2006: Matthias Feichtinger; Heinz Wiendl; Eva Körner; Alexander Holl; Lucia Gruber; Franz Fazekas; Oskar Schröttner; Hans Georg Eder; Erwin Ott
No effect of immunomodulatory therapy in focal epilepsy with positive glutamate receptor type 3--antibodies.
Seizure : the journal of the British Epilepsy Association 2006;15(5):350-4.
2006: Sven G Meuth; M Isabel Aller; Thomas Munsch; Thekla Schuhmacher; Thomas Seidenbecher; Patrick Meuth; Christoph Kleinschnitz; Hans-Christian Pape; Heinz Wiendl; william wisden; Thomas Budde
The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons.
Molecular pharmacology 2006;69(4):1468-76.
2006: Bernd C Kieseier; Heinz Wiendl
Multiple sclerosis: advances, excitements, disenchantments.
Lancet neurology 2006;5(1):2-3.
2006: Bettina Schreiner; Joachim Voss; Jörg Wischhusen; Yvonne Dombrowski; Alexander Steinle; Hanns Lochmüller; Marinos C Dalakas; Arthur Melms; Heinz Wiendl
Expression of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release and up-regulation of NKG2D-ligands.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):118-20.
2005: Til Menge; Bernhard Hemmer; Stefan Nessler; Heinz Wiendl; Oliver Neuhaus; Hans-Peter Hartung; Bernd C Kieseier; Olaf Stüve
Acute disseminated encephalomyelitis: an update.
Archives of neurology 2005;62(11):1673-80.
2005: Heinz Wiendl; Reinhard Hohlfeld; Bernd C Kieseier
Muscle-derived positive and negative regulators of the immune response.
Current opinion in rheumatology 2005;17(6):714-9.
2005: Oliver Neuhaus; Heinz Wiendl; Bernd C Kieseier; Juan J Archelos; Bernhard Hemmer; Olaf Stüve; Hans-Peter Hartung
Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro.
Journal of neuroimmunology 2005;168(1-2):128-37.
2005: Heinz Wiendl; Ute Feger; Michel Mittelbronn; Carolyn Jack; Bettina Schreiner; Christine Stadelmann; Jack Antel; Wolfgang Brueck; Richard Meyermann; Amit Bar-Or; Bernd C Kieseier; Michael Weller
Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity.
Brain : a journal of neurology 2005;128(Pt 11):2689-704.
2005: Bettina Schreiner; Bernd C Kieseier; Hans-Peter Hartung; R Hohlfeld; Heinz Wiendl
[Blocking adhesion molecules with natalizumab in multiple sclerosis].
Der Nervenarzt 2005;76(8):999-1005.
2005: Heinz Wiendl; Reinhard Hohlfeld; Bernd C Kieseier
Immunobiology of muscle: advances in understanding an immunological microenvironment.
Trends in immunology 2005;26(7):373-80.
2005: Antje Kroner; Matthias Mehling; Bernhard Hemmer; Peter Rieckmann; Klaus V Toyka; Mathias Mäurer; Heinz Wiendl
A PD-1 polymorphism is associated with disease progression in multiple sclerosis.
Annals of neurology 2005;58(1):50-7.
2005: Olaf Stüve; Stefan Nessler; Hans-Peter Hartung; Bernhard Hemmer; Heinz Wiendl; Bernd C Kieseier
[Acute disseminated encephalomyelitis. Pathogenesis, diagnosis, treatment, and prognosis].
Der Nervenarzt 2005;76(6):701-7.
2005: Thomas Leyhe; Christoph Laske; Gerhard Buchkremer; Henning Wormstall; Heinz Wiendl
[Dementia as a primary symptom in late onset multiple sclerosis. Case series and review of the literature].
Der Nervenarzt 2005;76(6):748-55.
2005: Jörg Wischhusen; Dagmar Schneider; Michel Mittelbronn; Richard Meyermann; Hartmut Engelmann; Gundram Jung; Heinz Wiendl; Michael Weller
Death receptor-mediated apoptosis in human malignant glioma cells: modulation by the CD40/CD40L system.
Journal of neuroimmunology 2005;162(1-2):28-42.
2005: Thomas Leyhe; Heinz Wiendl; Gerhard Buchkremer; Henning Wormstall
CADASIL: underdiagnosed in psychiatric patients?
Acta psychiatrica Scandinavica 2005;111(5):392-6; discussion 396-7.
2005: Sabine Krause; Stephan Hinderlich; Shira Amsili; Rüdiger Horstkorte; Heinz Wiendl; Zohar Argov; Stella Mitrani-Rosenbaum; Hanns Lochmüller
Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells.
Experimental cell research 2005;304(2):365-79.
2005: Tim Magnus; Bettina Schreiner; Thomas Korn; Carolyn Jack; Hong Guo; Jack Antel; Igal Ifergan; Lieping Chen; Felix Bischof; Amit Bar-Or; Heinz Wiendl
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2537-46.
2005: Meike Mitsdoerffer; Bettina Schreiner; Bernd C Kieseier; Oliver Neuhaus; Johannes Dichgans; Hans-Peter Hartung; Michael Weller; Heinz Wiendl
Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-beta in vitro and in vivo: rationale for the therapy of multiple sclerosis.
Journal of neuroimmunology 2005;159(1-2):155-64.
2005: Heinz Wiendl; Robert Weissert; Ulrich Herrlinger; Hilmar Krapf; Wilhelm Küker
Diffusion abnormality in Balo's concentric sclerosis: clues for the pathogenesis.
European neurology 2005;53(1):42-4.
2004: Bettina Schreiner; Meike Mitsdoerffer; Bernd C Kieseier; Lieping Chen; Hans-Peter Hartung; Michael Weller; Heinz Wiendl
Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis.
Journal of neuroimmunology 2004;155(1-2):172-82.
2004: Ulrich Herrlinger; Heinz Wiendl; M Renninger; H Förschler; Johannes Dichgans; Michael Weller
Vascular endothelial growth factor (VEGF) in leptomeningeal metastasis: diagnostic and prognostic value.
British journal of cancer 2004;91(2):219-24.
2004: Klaus Dornmair; Christian K Schneider; Joachim Malotka; Georg Dechant; Heinz Wiendl; Reinhard Hohlfeld
Antigen recognition properties of a Vgamma1.3Vdelta2-T-cell receptor from a rare variant of polymyositis.
Journal of neuroimmunology 2004;152(1-2):168-75.
2004: Heinz Wiendl; H C Lehmann; R Hohlfeld; Hans-Peter Hartung; Bernd C Kieseier
[Multiple sclerosis: potential therapeutic options and update of ongoing studies].
Der Nervenarzt 2004;75(6):536-52.
2004: Timo Burster; Alexander Beck; Eva Tolosa; Viviana Marin-Esteban; Olaf Rötzschke; Kirsten Falk; Alfred Lautwein; Michael Reich; Jens Brandenburg; Gerold Schwarz; Heinz Wiendl; Arthur Melms; Rainer Lehmann; Stefan Stevanovic; Hubert Kalbacher; Christoph Driessen
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5495-503.
2004: isabelle korn-lubetzki; Christian G Bien; Jan Bauer; M Gomori; Heinz Wiendl; L Trajo; H Ovadia; Bernd Wilken; Volkmar H Hans; C E Elger; Haggit Hurvitz; Israel Steiner
Rasmussen encephalitis with active inflammation and delayed seizures onset.
Neurology 2004;62(6):984-6.
2003: Sabine Krause; Beate Schlotter-Weigel; Maggie C Walter; Hossein Najmabadi; Heinz Wiendl; Josef Müller-Höcker; Wolfgang Müller-Felber; Dieter Pongratz; Hanns Lochmüller
A novel homozygous missense mutation in the GNE gene of a patient with quadriceps-sparing hereditary inclusion body myopathy associated with muscle inflammation.
Neuromuscular disorders : NMD 2003;13(10):830-4.
2003: Bettina Schreiner; Jörg Wischhusen; Meike Mitsdoerffer; Dagmar Schneider; Antje Bornemann; Arthur Melms; Eva Tolosa; Michael Weller; Heinz Wiendl
Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo.
Glia 2003;44(3):296-301.
2003: Sven G Meuth; Thomas Budde; Hüseyin Duyar; Peter Landgraf; Tilman Broicher; Martin Elbs; Roland Brock; Michael Weller; Robert Weissert; Heinz Wiendl
Modulation of neuronal activity by the endogenous pentapeptide QYNAD.
The European journal of neuroscience 2003;18(10):2697-706.
2003: Sabine Wintterle; Bettina Schreiner; Meike Mitsdoerffer; Dagmar Schneider; Lieping Chen; Richard Meyermann; Michael Weller; Heinz Wiendl
Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis.
Cancer research 2003;63(21):7462-7.
2003: Heinz Wiendl; Meike Mitsdoerffer; Michael Weller
Express and protect yourself: the potential role of HLA-G on muscle cells and in inflammatory myopathies.
Human immunology 2003;64(11):1050-6.
2003: Robert Weissert; Heinz Wiendl; Heike Pfrommer; Maria K Storch; Bettina Schreiner; Silvia Barth; Thomas Seifert; Arthur Melms; Johannes Dichgans; Michael Weller
Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes.
Journal of neuroimmunology 2003;144(1-2):28-37.
2003: Heinz Wiendl; Meike Mitsdoerffer; Michael Weller
Hide-and-seek in the brain: a role for HLA-G mediating immune privilege for glioma cells.
Seminars in cancer biology 2003;13(5):343-51.
2003: Heinz Wiendl; Meike Mitsdoerffer; Dagmar Schneider; Lieping Chen; Hanns Lochmüller; Arthur Melms; Michael Weller
Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1892-4.
2003: Oliver Neuhaus; Heinz Wiendl; Bernd C Kieseier; Juan J Archelos; Hans-Peter Hartung
[Cholesterol-reducing medications-a new therapeutic option for multiple sclerosis? Statins as immunomodulators].
Der Nervenarzt 2003;74(8):704-7.
2003: Heinz Wiendl; Oliver Neuhaus; Matthias Mehling; Sabine Wintterle; Bettina Schreiner; Meike Mitsdoerffer; Wolfgang Wienhold; Robert Weissert; Johannes Wessels; Hans-Peter Hartung; Michael Weller; Eva Tolosa; Arthur Melms
The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis.
Journal of neuroimmunology 2003;140(1-2):177-87.
2003: Heinz Wiendl; Alfred Lautwein; Meike Mitsdörffer; Sabine Krause; Stella Eugenie Autenrieth; Wolfgang Wienhold; Matthias Morgalla; Ekkehard Weber; Herman S Overkleeft; Hanns Lochmüller; Arthur Melms; Eva Tolosa; Christoph Driessen
Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies.
Journal of neuroimmunology 2003;138(1-2):132-43.
2003: Heinz Wiendl; Meike Mitsdoerffer; Dagmar Schneider; Arthur Melms; Hanns Lochmuller; Reinhard Hohlfeld; Michael Weller
Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies.
Brain : a journal of neurology 2003;126(Pt 5):1026-35.
2003: Heinz Wiendl; Matthias Mehling; J Dichgans; Arthur Melms; Katrin Bürk
The humoral response in the pathogenesis of gluten ataxia.
Neurology 2003;60(8):1397; author reply 1397-9.
2003: Robert Beck; Heinz Wiendl; Gerhard Jahn; Arthur Melms; Frank Neipel
Human herpesvirus 6 in serum and spinal fluid of patients with multiple sclerosis?
Archives of neurology 2003;60(4):639; author reply 639-40.
2003: Heinz Wiendl; Bernd C Kieseier
Disease-modifying therapies in multiple sclerosis: an update on recent and ongoing trials and future strategies.
Expert opinion on investigational drugs 2003;12(4):689-712.
2003: Heinz Wiendl; Meike Mitsdoerffer; Valeska Hofmeister; Jörg Wischhusen; Elisabeth H Weiss; Johannes Dichgans; Hanns Lochmuller; Reinhard Hohlfeld; Arthur Melms; Michael Weller
The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy.
Brain : a journal of neurology 2003;126(Pt 1):176-85.
2002: Robert Waltereit; Wilhelm Küker; Stefan Jürgens; Michael Weller; Johannes Dichgans; Heinz Wiendl
Acute transverse myelitis associated with coxiella burnetii infection.
Journal of neurology 2002;249(10):1459-61.
2002: Christian G Bien; Christian E Elger; Heinz Wiendl
Advances in pathogenic concepts and therapeutic agents in Rasmussen's encephalitis.
Expert opinion on investigational drugs 2002;11(7):981-9.
2002: Heinz Wiendl; Joachim Malotka; Brigitte Holzwarth; Hans Ulrich Weltzien; Hartmut Wekerle; Reinhard Hohlfeld; Klaus Dornmair
An autoreactive gamma delta TCR derived from a polymyositis lesion.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):515-21.
2002: Heinz Wiendl; Meike Mitsdoerffer; Valeska Hofmeister; Jörg Wischhusen; Antje Bornemann; Richard Meyermann; Elisabeth H Weiss; Arthur Melms; Michael Weller
A functional role of HLA-G expression in human gliomas: an alternative strategy of immune escape.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4772-80.
2002: Christian G Bien; Jan Bauer; Thomas L Deckwerth; Heinz Wiendl; Martina Deckert; Otmar D Wiestler; Johannes Schramm; Christian E Elger; Hans Lassmann
Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis.
Annals of neurology 2002;51(3):311-8.
2002: Heinz Wiendl; Reinhard Hohlfeld
Therapeutic approaches in multiple sclerosis: lessons from failed and interrupted treatment trials.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2002;16(3):183-200.
2002: Heinz Wiendl; M Strayle-Batra; J B Schulz
Very bright dorsal columns: spinal magnetic resonance imaging in funicular myelosis.
Archives of neurology 2002;59(1):147-8.
2001: Heinz Wiendl; Christian G Bien; P Bernasconi; B Fleckenstein; C E Elger; Johannes Dichgans; Renato Mantegazza; Arthur Melms
GluR3 antibodies: prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis.
Neurology 2001;57(8):1511-4.
2000: Heinz Wiendl; L Behrens; S Maier; M A Johnson; E H Weiss; Reinhard Hohlfeld
Muscle fibers in inflammatory myopathies and cultured myoblasts express the nonclassical major histocompatibility antigen HLA-G.
Annals of neurology 2000;48(4):679-84.
2000: Heinz Wiendl; Oliver Neuhaus; L Kappos; Reinhard Hohlfeld
[Multiple sclerosis. Current review of failed and discontinued clinical trials of drug treatment].
Der Nervenarzt 2000;71(8):597-610.
2000: Oliver Neuhaus; Cinthia Farina; A Yassouridis; Heinz Wiendl; Florian Then Bergh; TB Dose; Hartmut Wekerle; Reinhard Hohlfeld
Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7452-7.
1999: Heinz Wiendl; Oliver Neuhaus; H Stefan
[The therapy of Rasmussen encephalitis].
Deutsche medizinische Wochenschrift (1946) 1999;124(31-32):937-9.
1999: Heinz Wiendl; Oliver Neuhaus; H Stefan
[The pathogenesis and diagnosis of Rasmussen encephalitis].
Deutsche medizinische Wochenschrift (1946) 1999;124(30):901-4.