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Miriam Braunstein

Research Profile

Chemicals & Drugs

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Physiology

Anatomy

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Tuberculosis

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Acetylation

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Publications

TOP 3
Meghan E Feltcher; Henry S. Gibbons; Lauren S Ligon; Miriam Braunstein
Protein export by the mycobacterial SecA2 system is determined by the preprotein mature domain.
Irving C Allen; Janelle C Arthur; Miriam Braunstein; John David Lich; Erin McElvania-Tekippe; Jonathan T Sullivan; Justin E Wilson; Jenny P-Y Ting
Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis.
Meghan E Feltcher; Miriam Braunstein
Emerging themes in SecA2-mediated protein export.

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All Publications

2013: Meghan E Feltcher; Henry S. Gibbons; Lauren S Ligon; Miriam Braunstein
Protein export by the mycobacterial SecA2 system is determined by the preprotein mature domain.
Journal of bacteriology 2013;195(4):672-81.
2013: Irving C Allen; Janelle C Arthur; Miriam Braunstein; John David Lich; Erin McElvania-Tekippe; Jonathan T Sullivan; Justin E Wilson; Jenny P-Y Ting
Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis.
PloS one 2013;8(4):e60842.
2012: Meghan E Feltcher; Miriam Braunstein
Emerging themes in SecA2-mediated protein export.
Nature reviews. Microbiology 2012;10(11):779-89.
2012: Lauren S Ligon; Jennifer D Hayden; Miriam Braunstein
The ins and outs of Mycobacterium tuberculosis protein export.
Tuberculosis (Edinburgh, Scotland) 2012;92(2):121-32.
2011: Jessica R McCann; Justin A McDonough; Jonathan Tabb Sullivan; Meghan E Feltcher; Miriam Braunstein
Genome-wide identification of Mycobacterium tuberculosis exported proteins with roles in intracellular growth.
Journal of bacteriology 2011;193(4):854-61.
2010: Meghan E Feltcher; Jonathan Tabb Sullivan; Miriam Braunstein
Protein export systems of Mycobacterium tuberculosis: novel targets for drug development?
Future microbiology 2010;5(10):1581-97.
2010: Dongmei Lu; Lucila Garcia-Contreras; Pavan Muttil; Danielle Padilla; Ding Xu; Jian Liu; Miriam Braunstein; David N McMurray; Anthony J Hickey
Pulmonary immunization using antigen 85-B polymeric microparticles to boost tuberculosis immunity.
The AAPS journal 2010;12(3):338-47.
2010: Erin McElvania-Tekippe; Irving Allen; Paul D Hulseberg; Jonathan T Sullivan; Jessica R McCann; Matyas Sandor; Miriam Braunstein; Jenny P-Y Ting
Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1.
PloS one 2010;5(8):e12320.
2009: J D Hall; Sherry Kurtz; N W Rigel; B M Gunn; S Taft-Benz; J P Morrison; Alan M Fong; Dhavalkumar D Patel; Miriam Braunstein; Thomas H Kawula
The impact of chemokine receptor CX3CR1 deficiency during respiratory infections with Mycobacterium tuberculosis or Francisella tularensis.
Clinical and experimental immunology 2009;156(2):278-84.
2009: Nathan W Rigel; Henry S. Gibbons; Jessica R McCann; Justin A McDonough; Sherry Kurtz; Miriam Braunstein
The Accessory SecA2 System of Mycobacteria Requires ATP Binding and the Canonical SecA1.
The Journal of biological chemistry 2009;284(15):9927-36.
2009: Shanmugalakshmi Sadagopal; Miriam Braunstein; Cynthia C Hager; Jie Wei; Alexandria K Daniel; Markian R Bochan; Ian Crozier; Nathaniel E Smith; Hiriam O Gates; Louise Barnett; Luc Van Kaer; James O Price; Timothy S Blackwell; Spyros A Kalams; Douglas S Kernodle
Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG.
PloS one 2009;4(5):e5531.
2008: Justin A McDonough; Jessica R McCann; Erin McElvania Tekippe; Jason S Silverman; Nathan W Rigel; Miriam Braunstein
Identification of functional Tat signal sequences in Mycobacterium tuberculosis proteins.
Journal of bacteriology 2008;190(19):6428-38.
2008: Nathan W Rigel; Miriam Braunstein
A new twist on an old pathway--accessory Sec [corrected] systems.
Molecular microbiology 2008;69(2):291-302.
2008: Jie M Hou; Nadia G D'Lima; Nathan W Rigel; Henry S. Gibbons; Jessica R McCann; Miriam Braunstein; Carolyn M Teschke
ATPase activity of Mycobacterium tuberculosis SecA1 and SecA2 proteins and its importance for SecA2 function in macrophages.
Journal of bacteriology 2008;190(14):4880-7.
2008: Nilofar N Mohamedmohaideen; Satheesh K Palaninathan; Paul M Morin; Brad J Williams; Miriam Braunstein; Shane E Tichy; Joseph Locker; David H Russell; William R. Jacobs Jr.; James C Sacchettini
Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis.
Biochemistry 2008;47(23):6092-102.
2007: Jessica R McCann; Justin A McDonough; Martin S Pavelka; Miriam Braunstein
Beta-lactamase can function as a reporter of bacterial protein export during Mycobacterium tuberculosis infection of host cells.
Microbiology (Reading, England) 2007;153(Pt 10):3350-9.
2007: Dongmei Lu; Lucila Garcia-Contreras; Ding Xu; Sherry Kurtz; Jian Liu; Miriam Braunstein; David N McMurray; Anthony J Hickey
Poly (lactide-co-glycolide) microspheres in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen 85B.
Pharmaceutical research 2007;24(10):1834-43.
2007: Joseph Hinchey; Sunhee C Lee; Bo Y Jeon; Randall J Basaraba; Venkataswamy Manjunatha; Bing Chen; John Chan; Miriam Braunstein; Ian M Orme; Steven C Derrick; Sheldon L Morris; William R. Jacobs Jr.; Steven A Porcelli
Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis.
The Journal of clinical investigation 2007;117(8):2279-88.
2007: Henry S. Gibbons; Frank Wolschendorf; Michelle Abshire; Michael Niederweis; Miriam Braunstein
Identification of two Mycobacterium smegmatis lipoproteins exported by a SecA2-dependent pathway.
Journal of bacteriology 2007;189(14):5090-100.
2007: Xinzheng V Guo; Mercedes Monteleone; Marcus Klotzsche; Annette Kamionka; Wolfgang Hillen; Miriam Braunstein; Sabine Ehrt; Dirk Schnappinger
Silencing Mycobacterium smegmatis by using tetracycline repressors.
Journal of bacteriology 2007;189(13):4614-23.
2006: Sherry Kurtz; Karen P McKinnon; Marschall S Runge; Jenny P-Y Ting; Miriam Braunstein
The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response.
Infection and immunity 2006;74(12):6855-64.
2005: Kristi L Williams; John David Lich; Joseph A Duncan; William Reed; Prasad Rallabhandi; Christopher Moore; Sherry Kurtz; V McNeil Coffield; Mary A Accavitti-Loper; Lishan Su; Stefanie N Vogel; Miriam Braunstein; Jenny P-Y Ting
The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals.
The Journal of biological chemistry 2005;280(48):39914-24.
2005: Justin A McDonough; Kari E Hacker; Anthony R Flores; Martin S Pavelka; Miriam Braunstein
The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases.
Journal of bacteriology 2005;187(22):7667-79.
2003: Miriam Braunstein; Benjamin J Espinosa; John Chan; John Belisle; William R. Jacobs Jr.
SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis.
Molecular microbiology 2003;48(2):453-64.
2003: Vivek Sharma; Arulandu Arockiasamy; Donald Ronning; Christos G Savva; Andreas Holzenburg; Miriam Braunstein; William R. Jacobs Jr.; James C Sacchettini
Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2243-8.
2002: Miriam Braunstein; Stoyan S Bardarov; William R. Jacobs Jr.
Genetic methods for deciphering virulence determinants of Mycobacterium tuberculosis.
Methods in enzymology 2002;358():67-99.
2001: Miriam Braunstein; AMANDA BROWN; Sherry Kurtz; William R. Jacobs Jr.
Two nonredundant SecA homologues function in mycobacteria.
Journal of bacteriology 2001;183(24):6979-90.
2000: Miriam Braunstein; I V Griffin TJ; Jordan Kriakov; S T Friedman; N D Grindley; William R. Jacobs Jr.
Identification of genes encoding exported Mycobacterium tuberculosis proteins using a Tn552'phoA in vitro transposition system.
Journal of bacteriology 2000;182(10):2732-40.
1999: X Bi; Miriam Braunstein; G J Shei; James R Broach
The yeast HML I silencer defines a heterochromatin domain boundary by directional establishment of silencing.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):11934-9.
1996: Miriam Braunstein; R E Sobel; C D Allis; B M Turner; James R Broach
Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern.
Molecular and cellular biology 1996;16(8):4349-56.
1993: Miriam Braunstein; A B Rose; S G Holmes; C D Allis; James R Broach
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.
Genes & development 1993;7(4):592-604.