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Thomas Wight

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
26
Kinsella, Michael
24
Chait, Alan
19
Potter-Perigo, Susan
15
Snow, AD
13
Braun, Kathleen
13
Clowes, Alexander
11
Fischer, Jens
9
Järveläinen, Hannu
8
Tsoi, Christina
8
Sage, Helene
7
Lemire, Joan
7
O'Brien, Kevin
7
Lara, Stephanie
6
Johnson, Pamela
6
Nochlin, David

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Publications

TOP 3
Allison D D; Braun K R; Wight T N; Grande-Allen K J
Differential effects of exogenous and endogenous hyaluronan on contraction and strength of collagen gels.
True Lawrence D; Hawley Sarah; Norwood Thomas H; Braun Kathleen R; Evanko Stephen P; Chan Christina K; LeBaron Richard C; Wight Thomas N
The accumulation of versican in the nodules of benign prostatic hyperplasia.
Fleming Jo Nadine; Shulman Howard M; Nash Richard A; Johnson Pamela Y; Wight Thomas N; Gown Allen; Schwartz Stephen M
Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis.

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All Publications

2009: Allison D D; Braun K R; Wight T N; Grande-Allen K J
Differential effects of exogenous and endogenous hyaluronan on contraction and strength of collagen gels.
Acta biomaterialia 2009;5(4):1019-26.
2009: True Lawrence D; Hawley Sarah; Norwood Thomas H; Braun Kathleen R; Evanko Stephen P; Chan Christina K; LeBaron Richard C; Wight Thomas N
The accumulation of versican in the nodules of benign prostatic hyperplasia.
The Prostate 2009;69(2):149-58.
2009: Fleming Jo Nadine; Shulman Howard M; Nash Richard A; Johnson Pamela Y; Wight Thomas N; Gown Allen; Schwartz Stephen M
Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis.
PloS one 2009;4(7):e6203.
2008: Hwang Jin-Yong; Johnson Pamela Y; Braun Kathleen R; Hinek Aleksander; Fischer Jens W; O'Brien Kevin D; Starcher Barry; Clowes Alexander W; Merrilees Mervyn J; Wight Thomas N
Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injury.
The American journal of pathology 2008;173(6):1919-28.
2008: Nigro Julie; Potter-Perigo Susan; Ivey Melanie E; de Dios Stephanie T; Evanko Stephen P; Wight Thomas N; Little Peter J
The effect of PPAR ligands to modulate glucose metabolism alters the incorporation of metabolic precursors into proteoglycans synthesized by human vascular smooth muscle cells.
Archives of physiology and biochemistry 2008;114(3):171-7.
2008: Tran-Lundmark Karin; Tran Phan-Kiet; Paulsson-Berne Gabrielle; Fridén Vincent; Soininen Raija; Tryggvason Karl; Wight Thomas N; Kinsella Michael G; Borén Jan; Hedin Ulf
Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation.
Circulation research 2008;103(1):43-52.
2008: Allison David D; Wight Thomas N; Ripp Nicolas J; Braun Kathleen R; Grande-Allen Kathryn J
Endogenous overexpression of hyaluronan synthases within dynamically cultured collagen gels: Implications for vascular and valvular disease.
Biomaterials 2008;29(20):2969-76.
2008: Wight Thomas N
Arterial remodeling in vascular disease: a key role for hyaluronan and versican.
Frontiers in bioscience : a journal and virtual library 2008;13():4933-7.
2008: Merrilees Mervyn J; Ching Pamela S T; Beaumont Brent; Hinek Aleksander; Wight Thomas N; Black Peter N
Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease.
Respiratory research 2008;9():41.
2007: Allison David D; Vasco Natalia; Braun Kathleen R; Wight Thomas N; Grande-Allen K Jane
The effect of endogenous overexpression of hyaluronan synthases on material, morphological, and biochemical properties of uncrosslinked collagen biomaterials.
Biomaterials 2007;28(36):5509-17.
2007: McDonald Thomas O; Gerrity Ross G; Jen Christy; Chen Hao-Ji; Wark Kathleen; Wight Thomas N; Chait Alan; O'Brien Kevin D
Diabetes and arterial extracellular matrix changes in a porcine model of atherosclerosis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(11):1149-57.
2007: Chira Ebele C; McMillen Timothy S; Wang Shari; Haw Antonio; O'Brien Kevin D; Wight Thomas N; Chait Alan
Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice.
Atherosclerosis 2007;195(1):100-9.
2007: Gouëffic Yann; Potter-Perigo Susan; Chan Christina K; Johnson Pamela Y; Braun Kathleen; Evanko Steven P; Wight Thomas N
Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM.
Atherosclerosis 2007;195(1):23-30.
2007: Han Chang Yeop; Subramanian Savitha; Chan Christina K; Omer Mohamed; Chiba Tsuyoshi; Wight Thomas N; Chait Alan
Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion.
Diabetes 2007;56(9):2260-73.
2007: Lemire Joan M; Chan Christina K; Bressler Steven; Miller John; LeBaron Richard G; Wight Thomas N
Interleukin-1beta selectively decreases the synthesis of versican by arterial smooth muscle cells.
Journal of cellular biochemistry 2007;101(3):753-66.
2007: Johnson Pamela Y; Potter-Perigo Susan; Gooden Michel D; Vernon Robert B; Wight Thomas N
Decorin synthesized by arterial smooth muscle cells is retained in fibrin gels and modulates fibrin contraction.
Journal of cellular biochemistry 2007;101(2):281-94.
2006: Tannock Lisa R; Kirk Elizabeth A; King Victoria L; LeBoeuf Renee; Wight Thomas N; Chait Alan
Glucosamine supplementation accelerates early but not late atherosclerosis in LDL receptor-deficient mice.
The Journal of nutrition 2006;136(11):2856-61.
2006: Sullivan Millicent M; Barker Thomas H; Funk Sarah E; Karchin Ari; Seo Neung S; Höök Magnus; Sanders Joan; Starcher Barry; Wight Thomas N; Puolakkainen Pauli; Sage E Helene
Matricellular hevin regulates decorin production and collagen assembly.
The Journal of biological chemistry 2006;281(37):27621-32.
2006: Kenagy Richard D; Plaas Anna H; Wight Thomas N
Versican degradation and vascular disease.
Trends in cardiovascular medicine 2006;16(6):209-15.
2006: Järveläinen Hannu; Puolakkainen Pauli; Pakkanen Sari; Brown Eric L; Höök Magnus; Iozzo Renato V; Sage E Helene; Wight Thomas N
A role for decorin in cutaneous wound healing and angiogenesis.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(4):443-52.
2006: Otsuka Goro; Agah Ramtin; Frutkin Andrew D; Wight Thomas N; Dichek David A
Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):737-43.
2006: Chang Mary Y; Han Chang-Yeop; Wight Thomas N; Chait Alan
Antioxidants inhibit the ability of lysophosphatidylcholine to regulate proteoglycan synthesis.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(3):494-500.
2006: Huang Robert; Merrilees Mervyn J; Braun Kathleen; Beaumont Brent; Lemire Joan; Clowes Alexander W; Hinek Aleksander; Wight Thomas N
Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury.
Circulation research 2006;98(3):370-7.
2006: Wilkinson Thomas S; Bressler Steven L; Evanko Stephen P; Braun Kathleen R; Wight Thomas N
Overexpression of hyaluronan synthases alters vascular smooth muscle cell phenotype and promotes monocyte adhesion.
Journal of cellular physiology 2006;206(2):378-85.
2005: Vernon Robert B; Gooden Michel D; Lara Stephanie L; Wight Thomas N
Microgrooved fibrillar collagen membranes as scaffolds for cell support and alignment.
Biomaterials 2005;26(16):3131-40.
2005: Puolakkainen Pauli A; Bradshaw Amy D; Brekken Rolf A; Reed May J; Kyriakides Themis; Funk Sarah E; Gooden Michel D; Vernon Robert B; Wight Thomas N; Bornstein Paul; Sage E Helene
SPARC-thrombospondin-2-double-null mice exhibit enhanced cutaneous wound healing and increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(5):571-81.
2005: O'Brien Kevin D; McDonald Thomas O; Kunjathoor Vidya; Eng KimLi; Knopp Eleanor A; Lewis Katherine; Lopez Roland; Kirk Elizabeth A; Chait Alan; Wight Thomas N; deBeer Frederick C; LeBoeuf Renee C
Serum amyloid A and lipoprotein retention in murine models of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):785-90.
2005: Vernon Robert B; Gooden Michel D; Lara Stephanie L; Wight Thomas N
Native fibrillar collagen membranes of micron-scale and submicron thicknesses for cell support and perfusion.
Biomaterials 2005;26(10):1109-17.
2005: Kenagy Richard D; Fischer Jens W; Lara Stephanie; Sandy John D; Clowes Alexander W; Wight Thomas N
Accumulation and loss of extracellular matrix during shear stress-mediated intimal growth and regression in baboon vascular grafts.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(1):131-40.
2004: Nigro J; Ballinger M L; Dilley R J; Jennings G L R; Wight T N; Little P J
Fenofibrate modifies human vascular smooth muscle proteoglycans and reduces lipoprotein binding.
Diabetologia 2004;47(12):2105-13.
2004: Fischer Jens W; Steitz Susie A; Johnson Pamela Y; Burke Allen; Kolodgie Frank; Virmani Renu; Giachelli Cecilia; Wight Thomas N
Decorin promotes aortic smooth muscle cell calcification and colocalizes to calcified regions in human atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2391-6.
2004: O'Brien Kevin D; Lewis Katherine; Fischer Jens W; Johnson Pamela; Hwang Jin-Yong; Knopp Eleanor A; Kinsella Michael G; Barrett P Hugh R; Chait Alan; Wight Thomas N
Smooth muscle cell biglycan overexpression results in increased lipoprotein retention on extracellular matrix: implications for the retention of lipoproteins in atherosclerosis.
Atherosclerosis 2004;177(1):29-35.
2004: Lewis Katherine E; Kirk Elizabeth A; McDonald Thomas O; Wang Shari; Wight Thomas N; O'Brien Kevin D; Chait Alan
Increase in serum amyloid a evoked by dietary cholesterol is associated with increased atherosclerosis in mice.
Circulation 2004;110(5):540-5.
2004: Kinsella Michael G; Irvin Colleen; Reidy Michael A; Wight Thomas N
Removal of heparan sulfate by heparinase treatment inhibits FGF-2-dependent smooth muscle cell proliferation in injured rat carotid arteries.
Atherosclerosis 2004;175(1):51-7.
2004: Grande-Allen K Jane; Calabro Anthony; Gupta Vishal; Wight Thomas N; Hascall Vincent C; Vesely Ivan
Glycosaminoglycans and proteoglycans in normal mitral valve leaflets and chordae: association with regions of tensile and compressive loading.
Glycobiology 2004;14(7):621-33.
2004: Wilkinson Thomas S; Potter-Perigo Susan; Tsoi Christina; Altman Leonard C; Wight Thomas N
Pro- and anti-inflammatory factors cooperate to control hyaluronan synthesis in lung fibroblasts.
American journal of respiratory cell and molecular biology 2004;31(1):92-9.
2004: Wight Thomas N; Merrilees Mervyn J
Proteoglycans in atherosclerosis and restenosis: key roles for versican.
Circulation research 2004;94(9):1158-67.
2004: Tannock L R; Little P J; Tsoi C; Barrett P H R; Wight T N; Chait A
Thiazolidinediones reduce the LDL binding affinity of non-human primate vascular cell proteoglycans.
Diabetologia 2004;47(5):837-43.
2004: Hinek Aleksander; Braun Kathy R; Liu Kela; Wang Yanting; Wight Thomas N
Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patients.
The American journal of pathology 2004;164(1):119-31.
2004: Järveläinen Hannu; Vernon Robert B; Gooden Michel D; Francki Aleksandar; Lara Stephanie; Johnson Pamela Y; Kinsella Michael G; Sage E Helene; Wight Thomas N
Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):67-72.
2004: Potter-Perigo Susan; Baker Coralie; Tsoi Christina; Braun Kathleen R; Isenhath Scott; Altman Gaylene M; Altman Leonard C; Wight Thomas N
Regulation of proteoglycan synthesis by leukotriene d4 and epidermal growth factor in bronchial smooth muscle cells.
American journal of respiratory cell and molecular biology 2004;30(1):101-8.
2004: Kinsella Michael G; Bressler Steven L; Wight Thomas N
The regulated synthesis of versican, decorin, and biglycan: extracellular matrix proteoglycans that influence cellular phenotype.
Critical reviews in eukaryotic gene expression 2004;14(3):203-34.
2003: Meyers C Daniel; Tannock Lisa R; Wight Thomas N; Chait Alan
Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL.
Journal of lipid research 2003;44(11):2152-60.
2003: O'Brien Kevin D; Vuletic Simona; McDonald Thomas O; Wolfbauer Gertrud; Lewis Katherine; Tu An-Yue; Marcovina Santica; Wight Thomas N; Chait Alan; Albers John J
Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis.
Circulation 2003;108(3):270-4.
2003: Bradshaw Amy D; Puolakkainen Pauli; Dasgupta Jayasri; Davidson Jeffrey M; Wight Thomas N; Helene Sage E
SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength.
The Journal of investigative dermatology 2003;120(6):949-55.
2003: Potter-Perigo Susan; Hull Rebecca L; Tsoi Christina; Braun Kathleen R; Andrikopoulos Sofianos; Teague Jeanette; Bruce Verchere C; Kahn Steven E; Wight Thomas N
Proteoglycans synthesized and secreted by pancreatic islet beta-cells bind amylin.
Archives of biochemistry and biophysics 2003;413(2):182-90.
2003: Chang Mary Y; Tsoi Christina; Wight Thomas N; Chait Alan
Lysophosphatidylcholine regulates synthesis of biglycan and the proteoglycan form of macrophage colony stimulating factor.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(5):809-15.
2003: Frevert Charles W; Kinsella Michael G; Vathanaprida Charie; Goodman Richard B; Baskin Denis G; Proudfoot Amanda; Wells Timothy N C; Wight Thomas N; Martin Thomas R
Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue.
American journal of respiratory cell and molecular biology 2003;28(4):464-72.
2003: Kinsella Michael G; Tran Phan-Kiet; Weiser-Evans Mary C M; Reidy Michael; Majack Richard A; Wight Thomas N
Changes in perlecan expression during vascular injury: role in the inhibition of smooth muscle cell proliferation in the late lesion.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(4):608-14.
2003: Puolakkainen Pauli; Bradshaw Amy D; Kyriakides Themistoklis R; Reed May; Brekken Rolf; Wight Thomas; Bornstein Paul; Ratner Buddy; Sage E Helene
Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials.
The American journal of pathology 2003;162(2):627-35.
2002: Chung Ick-Mo; Gold Herman K; Schwartz Stephen M; Ikari Yuji; Reidy Michael A; Wight Thomas N
Enhanced extracellular matrix accumulation in restenosis of coronary arteries after stent deployment.
Journal of the American College of Cardiology 2002;40(12):2072-81.
2002: Olin-Lewis Katherine; Krauss Ronald M; La Belle Michael; Blanche Patricia J; Barrett P Hugh R; Wight Thomas N; Chait Alan
ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan.
Journal of lipid research 2002;43(11):1969-77.
2002: Wight Thomas N
Versican: a versatile extracellular matrix proteoglycan in cell biology.
Current opinion in cell biology 2002;14(5):617-23.
2002: Yan Qi; Clark John I; Wight Thomas N; Sage E Helene
Alterations in the lens capsule contribute to cataractogenesis in SPARC-null mice.
Journal of cell science 2002;115(Pt 13):2747-56.
2002: Olin-Lewis Katherine; Benton Jeana L; Rutledge John C; Baskin Denis G; Wight Thomas N; Chait Alan
Apolipoprotein E mediates the retention of high-density lipoproteins by mouse carotid arteries and cultured arterial smooth muscle cell extracellular matrices.
Circulation research 2002;90(12):1333-9.
2002: Merrilees Mervyn J; Lemire Joan M; Fischer Jens W; Kinsella Michael G; Braun Kathleen R; Clowes Alexander W; Wight Thomas N
Retrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injury.
Circulation research 2002;90(4):481-7.
2002: Kenagy Richard D; Fischer Jens W; Davies Mark G; Berceli Scott A; Hawkins Suzanne M; Wight Thomas N; Clowes Alexander W
Increased plasmin and serine proteinase activity during flow-induced intimal atrophy in baboon PTFE grafts.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(3):400-4.
2002: Toole Bryan P; Wight Thomas N; Tammi Markku I
Hyaluronan-cell interactions in cancer and vascular disease.
The Journal of biological chemistry 2002;277(7):4593-6.
2002: Lemire Joan M; Merrilees Mervyn J; Braun Kathleen R; Wight Thomas N
Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro.
Journal of cellular physiology 2002;190(1):38-45.
2002: Tannock Lisa R; Little Peter J; Wight Thomas N; Chait Alan
Arterial smooth muscle cell proteoglycans synthesized in the presence of glucosamine demonstrate reduced binding to LDL.
Journal of lipid research 2002;43(1):149-57.
2002: Tannock Lisa R; Olin Katherine L; Barrett P Hugh R; Wight Thomas N; Chait Alan
Triglyceride-rich lipoproteins from subjects with type 2 diabetes do not demonstrate increased binding to biglycan, a vascular proteoglycan.
The Journal of clinical endocrinology and metabolism 2002;87(1):35-40.
2002: Little Peter J; Tannock Lisa; Olin Katherine L; Chait Alan; Wight Thomas N
Proteoglycans synthesized by arterial smooth muscle cells in the presence of transforming growth factor-beta1 exhibit increased binding to LDLs.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(1):55-60.
2001: Evanko S P; Johnson P Y; Braun K R; Underhill C B; Dudhia J; Wight T N
Platelet-derived growth factor stimulates the formation of versican-hyaluronan aggregates and pericellular matrix expansion in arterial smooth muscle cells.
Archives of biochemistry and biophysics 2001;394(1):29-38.
2001: Lundmark K; Tran P K; Kinsella M G; Clowes A W; Wight T N; Hedin U
Perlecan inhibits smooth muscle cell adhesion to fibronectin: role of heparan sulfate.
Journal of cellular physiology 2001;188(1):67-74.
2001: Chang M Y; Potter-Perigo S; Wight T N; Chait A
Oxidized LDL bind to nonproteoglycan components of smooth muscle extracellular matrices.
Journal of lipid research 2001;42(5):824-33.
2001: Fischer J W; Kinsella M G; Levkau B; Clowes A W; Wight T N
Retroviral overexpression of decorin differentially affects the response of arterial smooth muscle cells to growth factors.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(5):777-84.
2001: Lee R T; Yamamoto C; Feng Y; Potter-Perigo S; Briggs W H; Landschulz K T; Turi T G; Thompson J F; Libby P; Wight T N
Mechanical strain induces specific changes in the synthesis and organization of proteoglycans by vascular smooth muscle cells.
The Journal of biological chemistry 2001;276(17):13847-51.
2001: Sandy J D; Westling J; Kenagy R D; Iruela-Arispe M L; Verscharen C; Rodriguez-Mazaneque J C; Zimmermann D R; Lemire J M; Fischer J W; Wight T N; Clowes A W
Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4.
The Journal of biological chemistry 2001;276(16):13372-8.
2001: Olin K L; Potter-Perigo S; Barrett P H; Wight T N; Chait A
Biglycan, a vascular proteoglycan, binds differently to HDL2 and HDL3: role of apoE.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(1):129-35.
2001: Lara S L; Evanko S P; Wight T N
Morphological evaluation of proteoglycans in cells and tissues.
Methods in molecular biology (Clifton, N.J.) 2001;171():271-90.
2001: Fischer J W; Kinsella M G; Hasenstab D; Clowes A W; Wight T N
Cell-mediated transfer of proteoglycan genes.
Methods in molecular biology (Clifton, N.J.) 2001;171():261-9.
2000: Kaneko E; Skinner M P; Raines E W; Yuan C; Rosenfeld M E; Wight T N; Ross R
Detection of dissection and remodeling of atherosclerotic lesions in rabbits after balloon angioplasty by magnetic-resonance imaging.
Coronary artery disease 2000;11(8):599-606.
2000: Chait A; Wight T N
Interaction of native and modified low-density lipoproteins with extracellular matrix.
Current opinion in lipidology 2000;11(5):457-63.
2000: Kinsella M G; Fischer J W; Mason D P; Wight T N
Retrovirally mediated expression of decorin by macrovascular endothelial cells. Effects on cellular migration and fibronectin fibrillogenesis in vitro.
The Journal of biological chemistry 2000;275(18):13924-32.
2000: Fischer J W; Kinsella M G; Clowes M M; Lara S; Clowes A W; Wight T N
Local expression of bovine decorin by cell-mediated gene transfer reduces neointimal formation after balloon injury in rats.
Circulation research 2000;86(6):676-83.
2000: Chang M Y; Potter-Perigo S; Tsoi C; Chait A; Wight T N
Oxidized low density lipoproteins regulate synthesis of monkey aortic smooth muscle cell proteoglycans that have enhanced native low density lipoprotein binding properties.
The Journal of biological chemistry 2000;275(7):4766-73.
1999: Olin K L; Potter-Perigo S; Barrett P H; Wight T N; Chait A
Lipoprotein lipase enhances the binding of native and oxidized low density lipoproteins to versican and biglycan synthesized by cultured arterial smooth muscle cells.
The Journal of biological chemistry 1999;274(49):34629-36.
1999: Andrikopoulos S; Verchere C B; Teague J C; Howell W M; Fujimoto W Y; Wight T N; Kahn S E
Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.
Diabetes 1999;48(10):1962-70.
1999: Evanko S P; Wight T N
Intracellular localization of hyaluronan in proliferating cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(10):1331-42.
1999: Lemire J M; Braun K R; Maurel P; Kaplan E D; Schwartz S M; Wight T N
Versican/PG-M isoforms in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(7):1630-9.
1999: Evanko S P; Angello J C; Wight T N
Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(4):1004-13.
1999: Castillo G M; Lukito W; Wight T N; Snow A D
The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation.
Journal of neurochemistry 1999;72(4):1681-7.
1998: Jabbour A J; Altman L C; Wight T N; Luchtel D L
Ozone alters the distribution of beta1 integrins in cultured primate bronchial epithelial cells.
American journal of respiratory cell and molecular biology 1998;19(3):357-65.
1998: O'Brien K D; Olin K L; Alpers C E; Chiu W; Ferguson M; Hudkins K; Wight T N; Chait A
Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: colocalization of biglycan with apolipoproteins.
Circulation 1998;98(6):519-27.
1998: Koyama N; Kinsella M G; Wight T N; Hedin U; Clowes A W
Heparan sulfate proteoglycans mediate a potent inhibitory signal for migration of vascular smooth muscle cells.
Circulation research 1998;83(3):305-13.
1998: Chang M Y; Olin K L; Tsoi C; Wight T N; Chait A
Human monocyte-derived macrophages secrete two forms of proteoglycan-macrophage colony-stimulating factor that differ in their ability to bind low density lipoproteins.
The Journal of biological chemistry 1998;273(26):15985-92.
1998: Potter-Perigo S; Kaplan E D; Luchtel D L; Baker C; Altman L C; Wight T N
Ozone alters the expression of tenascin-C in cultured primate nasal epithelial cells.
American journal of respiratory cell and molecular biology 1998;18(4):471-8.
1998: Evanko S P; Raines E W; Ross R; Gold L I; Wight T N
Proteoglycan distribution in lesions of atherosclerosis depends on lesion severity, structural characteristics, and the proximity of platelet-derived growth factor and transforming growth factor-beta.
The American journal of pathology 1998;152(2):533-46.
1997: Castillo G M; Ngo C; Cummings J; Wight T N; Snow A D
Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability.
Journal of neurochemistry 1997;69(6):2452-65.
1997: Miller J D; Cummings J; Maresh G A; Walker D G; Castillo G M; Ngo C; Kimata K; Kinsella M G; Wight T N; Snow A D
Localization of perlecan (or a perlecan-related macromolecule) to isolated microglia in vitro and to microglia/macrophages following infusion of beta-amyloid protein into rodent hippocampus.
Glia 1997;21(2):228-43.
1997: Wight T N; Lara S; Riessen R; Le Baron R; Isner J
Selective deposits of versican in the extracellular matrix of restenotic lesions from human peripheral arteries.
The American journal of pathology 1997;151(4):963-73.
1997: Schönherr E; Kinsella M G; Wight T N
Genistein selectively inhibits platelet-derived growth factor-stimulated versican biosynthesis in monkey arterial smooth muscle cells.
Archives of biochemistry and biophysics 1997;339(2):353-61.
1997: Kinsella M G; Tsoi C K; Järveläinen H T; Wight T N
Selective expression and processing of biglycan during migration of bovine aortic endothelial cells. The role of endogenous basic fibroblast growth factor.
The Journal of biological chemistry 1997;272(1):318-25.
1996: Potter-Perigo S; Wight T N
Heparin causes the accumulation of heparan sulfate in cultures of arterial smooth muscle cells.
Archives of biochemistry and biophysics 1996;336(1):19-26.
1996: Carlson S S; Iwata M; Wight T N
A chondroitin sulfate/keratan sulfate proteoglycan, PG-1000, forms complexes which are concentrated in the reticular laminae of electric organ basement membranes.
Matrix biology : journal of the International Society for Matrix Biology 1996;15(4):281-92.
1996: Halpert I; Sires U I; Roby J D; Potter-Perigo S; Wight T N; Shapiro S D; Welgus H G; Wickline S A; Parks W C
Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9748-53.
1996: Lemire J M; Potter-Perigo S; Hall K L; Wight T N; Schwartz S M
Distinct rat aortic smooth muscle cells differ in versican/PG-M expression.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(6):821-9.
1995: Snow A D; Kinsella M G; Parks E; Sekiguchi R T; Miller J D; Kimata K; Wight T N
Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease.
Archives of biochemistry and biophysics 1995;320(1):84-95.
1995: Ostberg C O; Zhu P; Wight T N; Qwarnstrom E E
Fibronectin attachment is permissive for IL-1 mediated gene regulation.
FEBS letters 1995;367(1):93-7.
1995: Vernon R B; Lara S L; Drake C J; Iruela-Arispe M L; Angello J C; Little C D; Wight T N; Sage E H
Organized type I collagen influences endothelial patterns during "spontaneous angiogenesis in vitro": planar cultures as models of vascular development.
In vitro cellular & developmental biology. Animal 1995;31(2):120-31.
1994: Sekiguchi R T; Potter-Perigo S; Braun K; Miller J; Ngo C; Fukuchi K; Wight T N; Kimata K; Snow A D
Characterization of proteoglycans synthesized by murine embryonal carcinoma cells (P19) reveals increased expression of perlecan (heparan sulfate proteoglycan) during neuronal differentiation.
Journal of neuroscience research 1994;38(6):670-86.
1994: Nikkari S T; Järveläinen H T; Wight T N; Ferguson M; Clowes A W
Smooth muscle cell expression of extracellular matrix genes after arterial injury.
The American journal of pathology 1994;144(6):1348-56.
1994: Yao L Y; Moody C; Schönherr E; Wight T N; Sandell L J
Identification of the proteoglycan versican in aorta and smooth muscle cells by DNA sequence analysis, in situ hybridization and immunohistochemistry.
Matrix biology : journal of the International Society for Matrix Biology 1994;14(3):213-25.
1993: Klebanoff S J; Kinsella M G; Wight T N
Degradation of endothelial cell matrix heparan sulfate proteoglycan by elastase and the myeloperoxidase-H2O2-chloride system.
The American journal of pathology 1993;143(3):907-17.
1993: Qwarnström E E; Järveläinen H T; Kinsella M G; Ostberg C O; Sandell L J; Page R C; Wight T N
Interleukin-1 beta regulation of fibroblast proteoglycan synthesis involves a decrease in versican steady-state mRNA levels.
The Biochemical journal 1993;294 ( Pt 2)():613-20.
1993: Iwata M; Wight T N; Carlson S S
A brain extracellular matrix proteoglycan forms aggregates with hyaluronan.
The Journal of biological chemistry 1993;268(20):15061-9.
1993: Schönherr E; Järveläinen H T; Kinsella M G; Sandell L J; Wight T N
Platelet-derived growth factor and transforming growth factor-beta 1 differentially affect the synthesis of biglycan and decorin by monkey arterial smooth muscle cells.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(7):1026-36.
1993: Potter-Perigo S; Prather P; Baker C; Altman L C; Wight T N
Partial characterization of proteoglycans synthesized by human gingival epithelial cells in culture.
Journal of periodontal research 1993;28(2):81-91.
1993: Juul S E; Kinsella M G; Wight T N; Hodson W A
Alterations in nonhuman primate (M. nemestrina) lung proteoglycans during normal development and acute hyaline membrane disease.
American journal of respiratory cell and molecular biology 1993;8(3):299-310.
1992: Järveläinen H T; Iruela-Arispe M L; Kinsella M G; Sandell L J; Sage E H; Wight T N
Expression of decorin by sprouting bovine aortic endothelial cells exhibiting angiogenesis in vitro.
Experimental cell research 1992;203(2):395-401.
1992: Wight T N; Kinsella M G; Qwarnström E E
The role of proteoglycans in cell adhesion, migration and proliferation.
Current opinion in cell biology 1992;4(5):793-801.
1992: Potter-Perigo S; Braun K R; Schönherr E; Wight T N
Altered proteoglycan synthesis via the false acceptor pathway can be dissociated from beta-D-xyloside inhibition of proliferation.
Archives of biochemistry and biophysics 1992;297(1):101-9.
1992: Fukuchi K; Deeb S S; Kamino K; Ogburn C E; Snow A D; Sekiguchi R T; Wight T N; Piussan H; Martin G M
Increased expression of beta-amyloid protein precursor and microtubule-associated protein tau during the differentiation of murine embryonal carcinoma cells.
Journal of neurochemistry 1992;58(5):1863-73.
1992: Yeo T K; Yeo K T; Wight T N
Differential transport kinetics of chondroitin sulfate and dermatan sulfate proteoglycan by monkey aorta smooth muscle cells.
Archives of biochemistry and biophysics 1992;294(1):9-16.
1992: Qwarnström E E; Kinsella M G; MacFarlane S A; Page R C; Wight T N
Modulation of proteoglycan metabolism by human fibroblasts maintained in an endogenous three-dimensional matrix.
European journal of cell biology 1992;57(1):101-8.
1992: Snow A D; Mar H; Nochlin D; Kresse H; Wight T N
Peripheral distribution of dermatan sulfate proteoglycans (decorin) in amyloid-containing plaques and their presence in neurofibrillary tangles of Alzheimer's disease.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992;40(1):105-13.
1992: Yeo T K; Macfarlane S; Wight T N
Characterization of a chondroitin sulfate proteoglycan synthesized by monkey arterial smooth muscle cells in vitro.
Connective tissue research 1992;27(4):265-77.
1991: Järveläinen H T; Kinsella M G; Wight T N; Sandell L J
Differential expression of small chondroitin/dermatan sulfate proteoglycans, PG-I/biglycan and PG-II/decorin, by vascular smooth muscle and endothelial cells in culture.
The Journal of biological chemistry 1991;266(34):23274-81.
1991: Snow A D; Bramson R; Mar H; Wight T N; Kisilevsky R
A temporal and ultrastructural relationship between heparan sulfate proteoglycans and AA amyloid in experimental amyloidosis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991;39(10):1321-30.
1991: Schönherr E; Järveläinen H T; Sandell L J; Wight T N
Effects of platelet-derived growth factor and transforming growth factor-beta 1 on the synthesis of a large versican-like chondroitin sulfate proteoglycan by arterial smooth muscle cells.
The Journal of biological chemistry 1991;266(26):17640-7.
1990: Snow A D; Mar H; Nochlin D; Sekiguchi R T; Kimata K; Koike Y; Wight T N
Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome.
The American journal of pathology 1990;137(5):1253-70.
1990: Snow A D; Wight T N; Nochlin D; Koike Y; Kimata K; DeArmond S J; Prusiner S B
Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie.
Laboratory investigation; a journal of technical methods and pathology 1990;63(5):601-11.
1990: Kinsella M G; Wight T N
Formation of high molecular weight dermatan sulfate proteoglycan in bovine aortic endothelial cell cultures. Evidence for transglutaminase-catalyzed cross-linking to fibronectin.
The Journal of biological chemistry 1990;265(29):17891-8.
1990: Snow A D; Bolender R P; Wight T N; Clowes A W
Heparin modulates the composition of the extracellular matrix domain surrounding arterial smooth muscle cells.
The American journal of pathology 1990;137(2):313-30.
1989: Wight T N; Potter-Perigo S; Aulinskas T
Proteoglycans and vascular cell proliferation.
The American review of respiratory disease 1989;140(4):1132-5.
1989: Snow A D; Wight T N
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses.
Neurobiology of aging 1989;10(5):481-97.
1989: Snow A D; Mar H; Nochlin D; Wight T N
Congo red staining on 1 micron de-plasticized sections for detection of lesions in Alzheimer's disease and related disorders.
Progress in clinical and biological research 1989;317():383-91.
1989: Snow A D; Lara S; Nochlin D; Wight T N
Cationic dyes reveal proteoglycans structurally integrated within the characteristic lesions of Alzheimer's disease.
Acta neuropathologica 1989;78(2):113-23.
1988: Kinsella M G; Wight T N
Isolation and characterization of dermatan sulfate proteoglycans synthesized by cultured bovine aortic endothelial cells.
The Journal of biological chemistry 1988;263(35):19222-31.
1988: Snow A D; Mar H; Nochlin D; Kimata K; Kato M; Suzuki S; Hassell J; Wight T N
The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease.
The American journal of pathology 1988;133(3):456-63.
1988: Mar H; Wight T N
Colloidal gold immunostaining on deplasticized ultra-thin sections.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1988;36(11):1387-95.
1988: Lark M W; Yeo T K; Mar H; Lara S; Hellström I; Hellström K E; Wight T N
Arterial chondroitin sulfate proteoglycan: localization with a monoclonal antibody.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1988;36(10):1211-21.
1988: Kinsella M G; Wight T N
Structural characterization of heparan sulfate proteoglycan subclasses isolated from bovine aortic endothelial cell cultures.
Biochemistry 1988;27(6):2136-44.
1987: Carlson S S; Wight T N
Nerve terminal anchorage protein 1 (TAP-1) is a chondroitin sulfate proteoglycan: biochemical and electron microscopic characterization.
The Journal of cell biology 1987;105(6 Pt 2):3075-86.
1987: Mar H; Tsukada T; Gown A M; Wight T N; Baskin D G
Correlative light and electron microscopic immunocytochemistry on the same section with colloidal gold.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1987;35(4):419-25.
1986: Garrigues H J; Lark M W; Lara S; Hellström I; Hellström K E; Wight T N
The melanoma proteoglycan: restricted expression on microspikes, a specific microdomain of the cell surface.
The Journal of cell biology 1986;103(5):1699-710.

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