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George Wilcox

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Issam El Ghazi; Wen S Sheng; Shuxian Hu; Brian G Reilly; James R Lokensgard; R Bryan Rock; Phillip K Peterson; George L Wilcox; Ian M Armitage
Changes in the NMR metabolic profile of human microglial cells exposed to lipopolysaccharide or morphine.
Brian L Schmidt; Darryl T Hamamoto; Donald A Simone; George L Wilcox
Mechanism of cancer pain.
Lucy Vulchanova; Daniel J Schuster; Lalitha R Belur; Maureen S Riedl; Kelly M Podetz-Pedersen; Kelley F Kitto; George L Wilcox; R Scott McIvor; Carolyn A Fairbanks
Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture.

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2010: Issam El Ghazi; Wen S Sheng; Shuxian Hu; Brian G Reilly; James R Lokensgard; R Bryan Rock; Phillip K Peterson; George L Wilcox; Ian M Armitage
Changes in the NMR metabolic profile of human microglial cells exposed to lipopolysaccharide or morphine.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2010;5(4):574-81.
2010: Brian L Schmidt; Darryl T Hamamoto; Donald A Simone; George L Wilcox
Mechanism of cancer pain.
Molecular interventions 2010;10(3):164-78.
2010: Lucy Vulchanova; Daniel J Schuster; Lalitha R Belur; Maureen S Riedl; Kelly M Podetz-Pedersen; Kelley F Kitto; George L Wilcox; R Scott McIvor; Carolyn A Fairbanks
Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture.
Molecular pain 2010;6():31.
2009: Aaron C Overland; Kelley F Kitto; Anne-Julie Chabot-Doré; Patrick E Rothwell; Carolyn A Fairbanks; Laura S Stone; George L Wilcox
Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(42):13264-73.
2009: Carolyn A Fairbanks; Laura S Stone; George L Wilcox
Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis.
Pharmacology & therapeutics 2009;123(2):224-38.
2009: Maureen S Riedl; Stephen A Schnell; Aaron C Overland; Anne-Julie Chabot-Doré; Anna M Taylor; Alfredo Ribeiro-da-Silva; Robert P Elde; George L Wilcox; Laura S Stone
Coexpression of alpha 2A-adrenergic and delta-opioid receptors in substance P-containing terminals in rat dorsal horn.
The Journal of comparative neurology 2009;513(4):385-98.
2009: Christoph Stein; J David Clark; Uhtaek Oh; Michael R Vasko; George L Wilcox; Aaron C Overland; Todd W Vanderah; Robert H Spencer
Peripheral mechanisms of pain and analgesia.
Brain research reviews 2009;60(1):90-113.
2009: Carolyn A Fairbanks; Kelley F Kitto; H Oanh Nguyen; Laura S Stone; George L Wilcox
Clonidine and dexmedetomidine produce antinociceptive synergy in mouse spinal cord.
Anesthesiology 2009;110(3):638-47.
2008: Kristin L Schreiber; Alvin J Beitz; George L Wilcox
Activation of spinal microglia in a murine model of peripheral inflammation-induced, long-lasting contralateral allodynia.
Neuroscience letters 2008;440(1):63-7.
2007: Laura S Stone; Kelley F Kitto; James Eisenach; Carolyn A Fairbanks; George L Wilcox
ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors.
The Journal of pharmacology and experimental therapeutics 2007;323(3):899-906.
2006: Jean-Philippe Vit; Peter T Ohara; Duc Tien; John R Fike; Laura Eikmeier; Alvin J Beitz; George L Wilcox; Luc Jasmin
The analgesic effect of low dose focal irradiation in a mouse model of bone cancer is associated with spinal changes in neuro-mediators of nociception.
Pain 2006;120(1-2):188-201.
2005: Paul W Wacnik; Christine M Baker; Michael J Herron; Betsy T Kren; Bruce R Blazar; George L Wilcox; Maria Hordinsky; Alvin J Beitz; Marna E Ericson
Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors.
Pain 2005;115(1-2):95-106.
2005: Paul W Wacnik; Laura Eikmeier; Donald A Simone; George L Wilcox; Alvin J Beitz
Nociceptive characteristics of tumor necrosis factor-alpha in naive and tumor-bearing mice.
Neuroscience 2005;132(2):479-91.
2004: Laura S Stone; George L Wilcox
Alpha-2-adrenergic and opioid receptor additivity in rat locus coeruleus neurons.
Neuroscience letters 2004;361(1-3):265-8.
2004: Laura S Stone; Lucy Vulchanova; Maureen S Riedl; Frank G Williams; George L Wilcox; Robert Elde
Effects of peripheral nerve injury on delta opioid receptor (DOR) immunoreactivity in the rat spinal cord.
Neuroscience letters 2004;361(1-3):208-11.
2004: Chengshui Zhao; Paul W Wacnik; Jill M Tall; David C Johns; George L Wilcox; Richard A Meyer; Srinivasa N Raja
Analgesic effects of a soy-containing diet in three murine bone cancer pain models.
The journal of pain : official journal of the American Pain Society 2004;5(2):104-10.
2003: Laura S Stone; Carolyn A Fairbanks; George L Wilcox
Moxonidine, a mixed alpha(2)-adrenergic and imidazoline receptor agonist, identifies a novel adrenergic target for spinal analgesia.
Annals of the New York Academy of Sciences 2003;1009():378-85.
2003: Lois J Kehl; Darryl T Hamamoto; Paul W Wacnik; Devin L Croft; Blake D Norsted; George L Wilcox; Donald A Simone
A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain.
Pain 2003;103(1-2):175-86.
2003: Chen-Guang Yu; Carolyn A Fairbanks; George L Wilcox; Robert P Yezierski
Effects of agmatine, interleukin-10, and cyclosporin on spontaneous pain behavior after excitotoxic spinal cord injury in rats.
The journal of pain : official journal of the American Pain Society 2003;4(3):129-40.
2003: Paul W Wacnik; Lois J Kehl; Thomas M Trempe; Margaret L Ramnaraine; Alvin J Beitz; George L Wilcox
Tumor implantation in mouse humerus evokes movement-related hyperalgesia exceeding that evoked by intramuscular carrageenan.
Pain 2003;101(1-2):175-86.
2002: Tinna M Laughlin; Kevin V Tram; George L Wilcox; Angela K Birnbaum
Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception.
The Journal of pharmacology and experimental therapeutics 2002;302(3):1168-75.
2002: Carolyn A Fairbanks; Laura S Stone; Kelley F Kitto; Hoang Oanh Nguyen; Ivan J Posthumus; George L Wilcox
alpha(2C)-Adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy.
The Journal of pharmacology and experimental therapeutics 2002;300(1):282-90.
2001: David M Cain; Paul W Wacnik; M Turner; Gwen Wendelschafer-Crabb; William R Kennedy; George L Wilcox; Donald A Simone
Functional interactions between tumor and peripheral nerve: changes in excitability and morphology of primary afferent fibers in a murine model of cancer pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(23):9367-76.
2001: Paul W Wacnik; Laura Eikmeier; Timothy Ruggles; Margaret L Ramnaraine; Bruce Walcheck; Alvin J Beitz; George L Wilcox
Functional interactions between tumor and peripheral nerve: morphology, algogen identification, and behavioral characterization of a new murine model of cancer pain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(23):9355-66.
2001: Tinna M Laughlin; A A Larson; George L Wilcox
Mechanisms of induction of persistent nociception by dynorphin.
The Journal of pharmacology and experimental therapeutics 2001;299(1):6-11.
2001: David M Cain; Paul W Wacnik; Laura Eikmeier; Alvin J Beitz; George L Wilcox; Donald A Simone
Functional interactions between tumor and peripheral nerve in a model of cancer pain in the mouse.
Pain medicine (Malden, Mass.) 2001;2(1):15-23.
2000: Chen-Guang Yu; Alexander E Marcillo; Carolyn A Fairbanks; George L Wilcox; Robert P Yezierski
Agmatine improves locomotor function and reduces tissue damage following spinal cord injury.
Neuroreport 2000;11(14):3203-7.
2000: Carolyn A Fairbanks; K L Schreiber; K L Brewer; Chen-Guang Yu; Laura S Stone; Kelley F Kitto; Hoang Oanh Nguyen; Brent M Grocholski; D W Shoeman; Lois J Kehl; Soundar Regunathan; D J Reis; Robert P Yezierski; George L Wilcox
Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10584-9.
2000: Carolyn A Fairbanks; Hoang Oanh Nguyen; Brent M Grocholski; George L Wilcox
Moxonidine, a selective imidazoline-alpha2 -adrenergic receptor agonist, produces spinal synergistic antihyperalgesia with morphine in nerve-injured mice.
Anesthesiology 2000;93(3):765-73.
2000: Carolyn A Fairbanks; George L Wilcox
Spinal plasticity of acute opioid tolerance.
Journal of biomedical science 2000;7(3):200-12.
2000: Tinna M Laughlin; John R Bethea; Robert P Yezierski; George L Wilcox
Cytokine involvement in dynorphin-induced allodynia.
Pain 2000;84(2-3):159-67.
2000: Carolyn A Fairbanks; I J Posthumus; Kelley F Kitto; Laura S Stone; George L Wilcox
Moxonidine, a selective imidazoline/alpha(2) adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice.
Pain 2000;84(1):13-20.
1999: Carolyn A Fairbanks; George L Wilcox
Moxonidine, a selective alpha2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice.
The Journal of pharmacology and experimental therapeutics 1999;290(1):403-12.
1999: Tinna M Laughlin; Kelley F Kitto; George L Wilcox
Redox manipulation of NMDA receptors in vivo: alteration of acute pain transmission and dynorphin-induced allodynia.
Pain 1999;80(1-2):37-43.
1999: Carolyn A Fairbanks; George L Wilcox
Spinal antinociceptive synergism between morphine and clonidine persists in mice made acutely or chronically tolerant to morphine.
The Journal of pharmacology and experimental therapeutics 1999;288(3):1107-16.
1999: Laura S Stone; Lucy Vulchanova; Maureen S Riedl; J Wang; Frank G Williams; George L Wilcox; Robert Elde
Effects of peripheral nerve injury on alpha-2A and alpha-2C adrenergic receptor immunoreactivity in the rat spinal cord.
Neuroscience 1999;93(4):1399-407.
1998: Laura S Stone; C Broberger; Lucy Vulchanova; George L Wilcox; T Hökfelt; Maureen S Riedl; Robert Elde
Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(15):5928-37.
1997: Laura S Stone; Carolyn A Fairbanks; Tinna M Laughlin; Hoang Oanh Nguyen; T M Bushy; M W Wessendorf; George L Wilcox
Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2.
Neuroreport 1997;8(14):3131-5.
1997: Laura S Stone; Leigh B MacMillan; Kelley F Kitto; Lee E Limbird; George L Wilcox
The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(18):7157-65.
1997: Carolyn A Fairbanks; George L Wilcox
Acute tolerance to spinally administered morphine compares mechanistically with chronically induced morphine tolerance.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1408-17.
1997: Tinna M Laughlin; Todd W Vanderah; JM Lashbrook; ML Nichols; Michael H Ossipov; Frank Porreca; George L Wilcox
Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors.
Pain 1997;72(1-2):253-60.
1997: Lois J Kehl; Carolyn A Fairbanks; Tinna M Laughlin; George L Wilcox
Neurogenesis in postnatal rat spinal cord: a study in primary culture.
Science (New York, N.Y.) 1997;276(5312):586-9.
1997: D R Wotta; A K Birnbaum; George L Wilcox; Robert Elde; Ping-Yee Law
mu-opioid receptor regulates CFTR coexpressed in Xenopus oocytes in a cAMP independent manner.
Brain research. Molecular brain research 1997;44(1):55-65.
1996: Todd W Vanderah; Tinna M Laughlin; J M Lashbrook; ML Nichols; George L Wilcox; Michael H Ossipov; T Philip Malan; F Porreca
Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone.
Pain 1996;68(2-3):275-81.
1996: Josephine Lai; Maureen S Riedl; Laura S Stone; Ulf Arvidsson; E J Bilsky; George L Wilcox; Robert Elde; F Porreca
Immunofluorescence analysis of antisense oligodeoxynucleotide-mediated 'knock-down' of the mouse delta opioid receptor in vitro and in vivo.
Neuroscience letters 1996;213(3):205-8.
1996: A K Roche; M Cook; George L Wilcox; KC Kajander
A nitric oxide synthesis inhibitor (L-NAME) reduces licking behavior and Fos-labeling in the spinal cord of rats during formalin-induced inflammation.
Pain 1996;66(2-3):331-41.
1995: D Budai; George L Wilcox; Alice A Larson
Effects of nitric oxide availability on responses of spinal wide dynamic range neurons to excitatory amino acids.
European journal of pharmacology 1995;278(1):39-47.
1995: A K Birnbaum; D R Wotta; Ping-Yee Law; George L Wilcox
Functional expression of adrenergic and opioid receptors in Xenopus oocytes: interaction between alpha 2- and beta 2-adrenergic receptors.
Brain research. Molecular brain research 1995;28(1):72-80.
1994: H H Wu; George L Wilcox; Steven C McLoon
Implantation of AtT-20 or genetically modified AtT-20/hENK cells in mouse spinal cord induced antinociception and opioid tolerance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(8):4806-14.
1994: H H Wu; B R Lester; Z Sun; George L Wilcox
Antinociception following implantation of mouse B16 melanoma cells in mouse and rat spinal cord.
Pain 1994;56(2):203-10.
1993: A A Alhaider; M Hamon; George L Wilcox
Intrathecal 5-methoxy-N,N-dimethyltryptamine in mice modulates 5-HT1 and 5-HT3 receptors.
European journal of pharmacology 1993;249(2):151-60.
1993: D Budai; L J Kehl; G I Poliac; George L Wilcox
An iconographic program for computer-controlled whole-cell voltage clamp experiments.
Journal of neuroscience methods 1993;48(1-2):65-74.
1993: A A Alhaider; George L Wilcox
Differential roles of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptor subtypes in modulating spinal nociceptive transmission in mice.
The Journal of pharmacology and experimental therapeutics 1993;265(1):378-85.
1993: H H Wu; Steven C McLoon; George L Wilcox
Antinociception following implantation of AtT-20 and genetically modified AtT-20/hENK cells in rat spinal cord.
Journal of neural transplantation & plasticity 1993;4(1):15-26.
1992: Kelley F Kitto; J E Haley; George L Wilcox
Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse.
Neuroscience letters 1992;148(1-2):1-5.
1992: S C Roerig; S Lei; Kelley F Kitto; J K Hylden; George L Wilcox
Spinal interactions between opioid and noradrenergic agonists in mice: multiplicativity involves delta and alpha-2 receptors.
The Journal of pharmacology and experimental therapeutics 1992;262(1):365-74.
1992: D Budai; George L Wilcox; Alice A Larson
Modulation of N-methyl-D-aspartate and (R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) responses of spinal nociceptive neurons by a N-terminal fragment of substance P.
European journal of pharmacology 1992;216(3):441-4.
1992: D Budai; George L Wilcox; Alice A Larson
Enhancement of NMDA-evoked neuronal activity by glycine in the rat spinal cord in vivo.
Neuroscience letters 1992;135(2):265-8.
1992: J E Haley; George L Wilcox; P F Chapman
The role of nitric oxide in hippocampal long-term potentiation.
Neuron 1992;8(2):211-6.
1991: A A Alhaider; S Z Lei; George L Wilcox
Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(7):1881-8.
1991: S C Roerig; R G Hoffman; A E Takemori; George L Wilcox; James M Fujimoto
Isobolographic analysis of analgesic interactions between intrathecally and intracerebroventricularly administered fentanyl, morphine and D-Ala2-D-Leu5-enkephalin in morphine-tolerant and nontolerant mice.
The Journal of pharmacology and experimental therapeutics 1991;257(3):1091-9.
1991: S Z Lei; A W Lipkowski; George L Wilcox
Opioid and neurokinin activities of substance P fragments and their analogs.
European journal of pharmacology 1991;193(2):209-15.
1990: L M Aanonsen; S Lei; George L Wilcox
Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord.
Pain 1990;41(3):309-21.
1989: L M Aanonsen; George L Wilcox
Muscimol, gamma-aminobutyric acidA receptors and excitatory amino acids in the mouse spinal cord.
The Journal of pharmacology and experimental therapeutics 1989;248(3):1034-8.
1989: A S Hwang; George L Wilcox
Baclofen, gamma-aminobutyric acidB receptors and substance P in the mouse spinal cord.
The Journal of pharmacology and experimental therapeutics 1989;248(3):1026-33.
1988: George L Wilcox
Pharmacological studies of grooming and scratching behavior elicited by spinal substance P and excitatory amino acids.
Annals of the New York Academy of Sciences 1988;525():228-36.
1987: L M Aanonsen; George L Wilcox
Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.
The Journal of pharmacology and experimental therapeutics 1987;243(1):9-19.
1987: A S Hwang; George L Wilcox
Analgesic properties of intrathecally administered heterocyclic antidepressants.
Pain 1987;28(3):343-55.
1986: A S Hwang; George L Wilcox
Intradermal hypertonic saline-induced behavior as a nociceptive test in mice.
Life sciences 1986;38(26):2389-96.
1986: L M Aanonsen; George L Wilcox
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Neuroscience letters 1986;67(2):191-7.
1984: L J Kehl; George L Wilcox
Anti-nociceptive effect of tricyclic anti-depressants following intrathecal administration.
Anesthesia progress 1984;31(2):82-4.