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John Wilkinson

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Eric M Lewis; Rohit Mehra; Sooryanarayana Lnu; Amanda S Wilkinson; Arul M Chinnaiyan; Jacqueline S Jackson; John C Wilkinson
The enzymatic activity of apoptosis-inducing factor supports energy metabolism benefiting the growth and invasiveness of advanced prostate cancer cells.
Ryan P Topping; John C Wilkinson; Karin Drotschmann Scarpinato
Mismatch repair protein deficiency compromises cisplatin-induced apoptotic signaling.
Yan Jiao; John C Wilkinson; Xiumin Di; Wei Wang; Heather Hatcher; Nancy D Kock; Ralph D'Agostino; Mary Ann Knovich; Frank M Torti; Suzy V Torti
Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator.

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All Publications

2012: Eric M Lewis; Rohit Mehra; Sooryanarayana Lnu; Amanda S Wilkinson; Arul M Chinnaiyan; Jacqueline S Jackson; John C Wilkinson
The enzymatic activity of apoptosis-inducing factor supports energy metabolism benefiting the growth and invasiveness of advanced prostate cancer cells.
The Journal of biological chemistry 2012;287(52):43862-75.
2009: Ryan P Topping; John C Wilkinson; Karin Drotschmann Scarpinato
Mismatch repair protein deficiency compromises cisplatin-induced apoptotic signaling.
The Journal of biological chemistry 2009;284(21):14029-39.
2009: Yan Jiao; John C Wilkinson; Xiumin Di; Wei Wang; Heather Hatcher; Nancy D Kock; Ralph D'Agostino; Mary Ann Knovich; Frank M Torti; Suzy V Torti
Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator.
Blood 2009;113(2):462-9.
2008: John C Wilkinson; Amanda S Wilkinson; Stefanie Galban; Rebecca A Csomos; Colin S Duckett
Apoptosis-inducing factor is a target for ubiquitination through interaction with XIAP.
Molecular and cellular biology 2008;28(1):237-47.
2008: Clara Hwang; Veda N Giri; John C Wilkinson; Casey W Wright; Amanda S Wilkinson; Kathleen Cooney; Colin S Duckett
EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor.
Breast cancer research and treatment 2008;107(2):235-42.
2006: John C Wilkinson; Xiumin Di; Kai Schönig; Joan L Buss; Nancy D Kock; J Mark Cline; Thomas L Saunders; Hermann Bujard; Suzy V Torti; Frank M Torti
Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo.
The Biochemical journal 2006;395(3):501-7.
2006: Yan Jiao; John C Wilkinson; E Christine Pietsch; Joan L Buss; Wei Wang; Roy P Planalp; Frank M Torti; Suzy V Torti
Iron chelation in the biological activity of curcumin.
Free radical biology & medicine 2006;40(7):1152-60.
2006: Arjmand R Mufti; Ezra Burstein; Rebecca A Csomos; Paul C F Graf; John C Wilkinson; Robert D Dick; Madhavi Challa; Jae-Kyoung Son; Shawn B Bratton; Grace L Su; George J Brewer; Ursula Jakob; Colin S Duckett
XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders.
Molecular cell 2006;21(6):775-85.
2005: Ezra Burstein; Jamie E Hoberg; Amanda S Wilkinson; Julie M Rumble; Rebecca A Csomos; Christine M Komarck; Gabriel N Maine; John C Wilkinson; Marty W Mayo; Colin S Duckett
COMMD proteins, a novel family of structural and functional homologs of MURR1.
The Journal of biological chemistry 2005;280(23):22222-32.
2005: Merideth C Kamradt; Meiling Lu; Michael E Werner; Toni Kwan; Feng Chen; Anne Strohecker; Shayna Oshita; John C Wilkinson; Chunjiang Yu; Patsy G Oliver; Colin S Duckett; Donald J Buchsbaum; Albert F LoBuglio; V Craig Jordan; Vincent L Cryns
The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.
The Journal of biological chemistry 2005;280(12):11059-66.
2004: John C Wilkinson; Bettina W M Richter; Amanda S Wilkinson; Ezra Burstein; Julie M Rumble; Blerina Balliu; Colin S Duckett
VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation.
The Journal of biological chemistry 2004;279(49):51091-9.
2004: John C Wilkinson; Amanda S Wilkinson; Fiona L Scott; Rebecca A Csomos; Guy S Salvesen; Colin S Duckett
Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition.
The Journal of biological chemistry 2004;279(49):51082-90.
2004: John C Wilkinson; Enrique Cepero; Lawrence Boise; Colin S Duckett
Upstream regulatory role for XIAP in receptor-mediated apoptosis.
Molecular and cellular biology 2004;24(16):7003-14.
2004: Elena Beltrami; Janet Plescia; John C Wilkinson; Colin S Duckett; Dario C Altieri
Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis.
The Journal of biological chemistry 2004;279(3):2077-84.
2004: Ezra Burstein; Lakshmanan Ganesh; Robert D Dick; Bart van De Sluis; John C Wilkinson; Leo W J Klomp; Cisca Wijmenga; George J Brewer; Gary Nabel; Colin S Duckett
A novel role for XIAP in copper homeostasis through regulation of MURR1.
The EMBO journal 2004;23(1):244-54.
2003: Hwain Shin; Kazuya Okada; John C Wilkinson; Katherine M Solomon; Colin S Duckett; John C Reed; Guy S Salvesen
Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein.
The Biochemical journal 2003;373(Pt 3):965-71.
2003: Jonathan Ewald; John C Wilkinson; Cheryl A Guyer; James V Staros
Ligand- and kinase activity-independent cell survival mediated by the epidermal growth factor receptor expressed in 32D cells.
Experimental cell research 2003;282(2):121-31.
2003: John C Wilkinson; E Christine Pietsch; Suzy V Torti; Frank M Torti
Ferritin regulation by oxidants and chemopreventive xenobiotics.
Advances in enzyme regulation 2003;43():135-51.
2002: Bryan T Greene; Jacqueline Thorburn; Mark C Willingham; Andrew Thorburn; Roy P Planalp; Martin W Brechbiel; Jamie E Jennings-Gee; John C Wilkinson; Frank M Torti; Suzy V Torti
Activation of caspase pathways during iron chelator-mediated apoptosis.
The Journal of biological chemistry 2002;277(28):25568-75.
2002: John C Wilkinson; Joseph M Beechem; James V Staros
A stopped-flow fluorescence anisotropy method for measuring hormone binding and dissociation kinetics with cell-surface receptors in living cells.
Journal of receptor and signal transduction research 2002;22(1-4):357-71.
2002: John C Wilkinson; James V Staros
Effect of ErbB2 coexpression on the kinetic interactions of epidermal growth factor with its receptor in intact cells.
Biochemistry 2002;41(1):8-14.
2002: Bruce Ruggeri; Candy Robinson; Thelma S Angeles; John C Wilkinson; Margie L Clapper
The chemopreventive agent oltipraz possesses potent antiangiogenic activity in vitro, ex vivo, and in vivo and inhibits tumor xenograft growth.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):267-74.
2001: John M Stafford; John C Wilkinson; Joseph M Beechem; Daryl K Granner
Accessory factors facilitate the binding of glucocorticoid receptor to the phosphoenolpyruvate carboxykinase gene promoter.
The Journal of biological chemistry 2001;276(43):39885-91.
2001: John C Wilkinson; Richard A Stein; Cheryl A Guyer; Joseph M Beechem; James V Staros
Real-time kinetics of ligand/cell surface receptor interactions in living cells: binding of epidermal growth factor to the epidermal growth factor receptor.
Biochemistry 2001;40(34):10230-42.
2001: Richard A Stein; John C Wilkinson; Cheryl A Guyer; James V Staros
An analytical approach to the measurement of equilibrium binding constants: application to EGF binding to EGF receptors in intact cells measured by flow cytometry.
Biochemistry 2001;40(20):6142-54.
1998: John C Wilkinson; V Radjendirane; Gordon R Pfeiffer; Anil K Jaiswal; Margie L Clapper
Disruption of c-Fos leads to increased expression of NAD(P)H:quinone oxidoreductase1 and glutathione S-transferase.
Biochemical and biophysical research communications 1998;253(3):855-8.
1997: John C Wilkinson; Margie L Clapper
Detoxication enzymes and chemoprevention.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;216(2):192-200.