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Nick Willcox

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Jüri Kärner; Tadej Battelino; Nina Bratanic; Eystein S Husebye; Erkki Juronen; Maris Laan; J Maslovskaja; Anthony Meager; Pärt Peterson; M Pihlap; K T Podkrajšek; A Remm; Nick Willcox; Anette S Bøe Wolff; Kalle V Kisand
Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.
Alejandro M Gomez; Wim Buurman; Marc H De Baets; Pilar Martinez-Martinez; Peter C Molenaar; Nick Willcox; Mario Losen
Targeting plasma cells with proteasome inhibitors: possible roles in treating myasthenia gravis?
Kalle V Kisand; Desa Lilic; Jean-Laurent Casanova; Pärt Peterson; Anthony Meager; Nick Willcox
Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: clinical and pathogenetic implications.

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All Publications

2013: Jüri Kärner; Tadej Battelino; Nina Bratanic; Eystein S Husebye; Erkki Juronen; Maris Laan; J Maslovskaja; Anthony Meager; Pärt Peterson; M Pihlap; K T Podkrajšek; A Remm; Nick Willcox; Anette S Bøe Wolff; Kalle V Kisand
Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice.
Clinical and experimental immunology 2013;171(3):263-72.
2012: Alejandro M Gomez; Wim Buurman; Marc H De Baets; Pilar Martinez-Martinez; Peter C Molenaar; Nick Willcox; Mario Losen
Targeting plasma cells with proteasome inhibitors: possible roles in treating myasthenia gravis?
Annals of the New York Academy of Sciences 2012;1274():48-59.
2011: Kalle V Kisand; Desa Lilic; Jean-Laurent Casanova; Pärt Peterson; Anthony Meager; Nick Willcox
Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: clinical and pathogenetic implications.
European journal of immunology 2011;41(6):1517-27.
2011: Maarten Titulaer; Paul Maddison; Jacob K Sont; Paul W Wirtz; David Hilton-Jones; Rinse Klooster; Nick Willcox; Marko Potman; Peter A E Sillevis Smitt; J B M Kuks; Bart O Roep; Angela Vincent; Silvère M van der Maarel; J Gert van Dijk; Bethan Lang; Jan J Verschuuren
Clinical Dutch-English Lambert-Eaton Myasthenic syndrome (LEMS) tumor association prediction score accurately predicts small-cell lung cancer in the LEMS.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(7):902-8.
2010: Alexander Marx; Peter Hohenberger; Hans Hoffmann; joachim pfannschmidt; Philipp A Schnabel; Hans-Stefan Hofmann; Karsten Wiebe; Berthold Schalke; Wilfred Nix; Ralf Gold; Nick Willcox; Pärt Peterson; Philipp Ströbel
The autoimmune regulator AIRE in thymoma biology: autoimmunity and beyond.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(10 Suppl 4):S266-72.
2010: Alexander Marx; Nick Willcox; M I Leite; Wen-Yu Chuang; Berthold Schalke; Wilfred Nix; Philipp Ströbel
Thymoma and paraneoplastic myasthenia gravis.
Autoimmunity 2010;43(5-6):413-27.
2010: Kai Kisand; Anette S Bøe Wolff; Katarina Trebusak Podkrajsek; Liina Tserel; Maire Link; Kalle V Kisand; Elisabeth Ersvaer; Jaakko Perheentupa; Martina Moter Erichsen; Nina Bratanic; Antonella Meloni; Filomena Cetani; Roberto Perniola; Berrin Ergun-Longmire; Noel Maclaren; KJ Krohn; Mikulás Pura; Berthold Schalke; Philipp Ströbel; Maria Isabel Leite; Tadej Battelino; Eystein S Husebye; Pärt Peterson; Nick Willcox; Anthony Meager
Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines.
The Journal of experimental medicine 2010;207(2):299-308.
2008: Antonella Meloni; Maria Furcas; Filomena Cetani; Claudio Marcocci; Alberto Falorni; Roberto Perniola; mikulas pura; Anette S Bøe Wolff; Eystein S Husebye; Desa Lilic; Kelli R Ryan; Andrew R Gennery; Andrew J Cant; Mario Abinun; Gavin P Spickett; Peter Arkwright; David Denning; Colm Costigan; Maria Dominguez; Vivienne McConnell; Nick Willcox; Anthony Meager
Autoantibodies against type I interferons as an additional diagnostic criterion for autoimmune polyendocrine syndrome type I.
The Journal of clinical endocrinology and metabolism 2008;93(11):4389-97.
2008: Anthony Meager; Pärt Peterson; Nick Willcox
Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes.
Clinical and experimental immunology 2008;154(1):141-51.
2008: Kai Kisand; Maire Link; Anette S B Wolff; Anthony Meager; Liina Tserel; Tõnis Org; Astrid Murumägi; Raivo Uibo; Nick Willcox; Katarina Trebusak Podkrajsek; Tadej Battelino; Anna Lobell; Kämpe Olle; Kari Lima; Antonella Meloni; Berrin Ergun-Longmire; Noel K Maclaren; Jaakko Perheentupa; KJ Krohn; Hamish Scott; Eystein S Husebye; Pärt Peterson
Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes.
Blood 2008;112(7):2657-66.
2008: Nick Willcox
The legacy of John Newsom-Davis (1932-2007).
Journal of neuroimmunology 2008;201-202():1.
2008: CA MacLennan; Angela Vincent; Alexander Marx; Nick Willcox; Nils Eric Gilhus; John Newsom-Davis; David Beeson
Preferential expression of AChR epsilon-subunit in thymomas from patients with myasthenia gravis.
Journal of neuroimmunology 2008;201-202():28-32.
2008: Philipp Ströbel; Regina Moritz; Maria Isabel Leite; Nick Willcox; Wen-Yu Chuang; Ralf Gold; Wilfred Nix; Berthold Schalke; Reinhard Kiefer; Hans Konrad Müller-Hermelink; Alfred Jaretzki Iii; John Newsom-Davis; Alexander Marx
The ageing and myasthenic thymus: a morphometric study validating a standard procedure in the histological workup of thymic specimens.
Journal of neuroimmunology 2008;201-202():64-73.
2008: Maria Isabel Leite; Saiju Jacob; Stuart Viegas; Judy Cossins; Linda Clover; B Paul Morgan; David Beeson; Nick Willcox; Angela Vincent
IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis.
Brain : a journal of neurology 2008;131(Pt 7):1940-52.
2008: Nick Willcox; Maria Isabel Leite; Yoshihisa Kadota; Margaret Jones; Anthony Meager; Peddasomayajula Subrahmanyam; Bhaskar Dasgupta; B Paul Morgan; Angela Vincent
Autoimmunizing mechanisms in thymoma and thymus.
Annals of the New York Academy of Sciences 2008;1132():163-73.
2007: Maria Isabel Leite; Margaret Jones; Philipp Ströbel; Alexander Marx; Ralf Gold; Erik H Niks; Jan J Verschuuren; Sonia Berrih-Aknin; Francesco Scaravilli; Aurea Canelhas; B Paul Morgan; Angela Vincent; Nick Willcox
Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status.
The American journal of pathology 2007;171(3):893-905.
2007: Philipp Ströbel; Astrid Murumägi; R Klein; M Luster; M Lahti; Kai Krohn; Berthold Schalke; Wilfred Nix; Ralf Gold; Peter Rieckmann; Klaus V Toyka; Christof Burek; Andreas Rosenwald; Hans Konrad Müller-Hermelink; R Pujoll-Borrell; Anthony Meager; Nick Willcox; Pärt Peterson; Alexander Marx
Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1).
The Journal of pathology 2007;211(5):563-71.
2006: Manuel A Friese; Lise T Jensen; Nick Willcox; Lars Fugger
Humanized mouse models for organ-specific autoimmune diseases.
Current opinion in immunology 2006;18(6):704-9.
2006: Manuel A Friese; Xavier Montalban; Nick Willcox; John I Bell; Roland Martin; Lars Fugger
The value of animal models for drug development in multiple sclerosis.
Brain : a journal of neurology 2006;129(Pt 8):1940-52.
2006: Anthony Meager; Kumuthini Visvalingam; Pärt Peterson; Kaidi Möll; Astrid Murumägi; Kai Krohn; Petra Eskelin; Jaakko Perheentupa; Eystein S Husebye; Yoshihisa Kadota; Nick Willcox
Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1.
PLoS medicine 2006;3(7):e289.
2006: Bethan Lang; Nick Willcox
Autoantibodies in neuromuscular autoimmune disorders.
Expert review of clinical immunology 2006;2(2):293-307.
2005: Maria Isabel Leite; Philipp Ströbel; Margaret Jones; Kingsley Micklem; Regina Moritz; Ralf Gold; Erik H Niks; Sonia Berrih-Aknin; Francesco Scaravilli; Aurea Canelhas; Alexander Marx; John Newsom-Davis; Nick Willcox; Angela Vincent
Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.
Annals of neurology 2005;57(3):444-8.
2005: Paul W Wirtz; Nick Willcox; Arno R van der Slik; Bethan Lang; Paul Maddison; Bobby P C Koeleman; Marius J Giphart; Axel R Wintzen; Bart O Roep; Jan J Verschuuren
HLA and smoking in prediction and prognosis of small cell lung cancer in autoimmune Lambert-Eaton myasthenic syndrome.
Journal of neuroimmunology 2005;159(1-2):230-7.
2005: Kamil R Kranc; Andrew M Taylor; Nick Willcox; Lars Fugger
Control of autoimmunity by "epitope theft".
Trends in molecular medicine 2005;11(1):1-4.
2004: Pia Svendsen; Claus B Andersen; Nick Willcox; Anthony J Coyle; Rikard Holmdahl; Thomas Kamradt; Lars Fugger
Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):7037-45.
2004: Domenico Marco Bonifati; Nick Willcox; Angela Vincent; David Beeson
Lack of association between acetylcholine receptor epsilon polymorphisms and early-onset myasthenia gravis.
Muscle & nerve 2004;29(3):436-9.
2003: Uday Kishore; Wei Zhang; Louise Corlett; Patrick Waters; Nicolas Glaichenhaus; Nick Willcox
Use of peptide: HLA class II complexes to study specific T cells in autoimmune myasthenia gravis.
Annals of the New York Academy of Sciences 2003;998():339-42.
2003: Angela Vincent; John McConville; Maria Elena Farrugia; John Bowen; Paul Plested; Teresa Tang; Amelia Evoli; Ian Matthews; Gary P Sims; Paola Dalton; Leslie Jacobson; Agata Polizzi; Frans Blaes; Bethan Lang; David Beeson; Nick Willcox; John Newsom-Davis; Werner Hoch
Antibodies in myasthenia gravis and related disorders.
Annals of the New York Academy of Sciences 2003;998():324-35.
2003: Hiroyuki Shiono; Ioannis Roxanis; Wei Zhang; Gary P Sims; Anthony Meager; LW Jacobson; Jian-Li Liu; Ian Matthews; Y-L Wong; M Bonifati; Kingsley Micklem; David I Stott; John A Todd; David Beeson; Angela Vincent; Nick Willcox
Scenarios for autoimmunization of T and B cells in myasthenia gravis.
Annals of the New York Academy of Sciences 2003;998():237-56.
2003: Paul W Wirtz; Nick Willcox; Bart O Roep; Bethan Lang; Axel R Wintzen; John Newsom-Davis; Jan J Verschuuren
HLA-B8 in patients with the Lambert-Eaton myasthenic syndrome reduces likelihood of associated small cell lung carcinoma.
Annals of the New York Academy of Sciences 2003;998():200-1.
2003: Hiroyuki Shiono; Yat Lei Wong; Ian Matthews; Jian-Li Liu; Wei Zhang; Gary P Sims; Anthony Meager; David Beeson; Angela Vincent; Nick Willcox
Spontaneous production of anti-IFN-alpha and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor.
International immunology 2003;15(8):903-13.
2003: Masayoshi Inoue; Petr Starostik; Andreas Zettl; Philipp Ströbel; Stephan Schwarz; Francesco Scaravilli; Kristin Henry; Nick Willcox; Hans Konrad Müller-Hermelink; Alexander Marx
Correlating genetic aberrations with World Health Organization-defined histology and stage across the spectrum of thymomas.
Cancer research 2003;63(13):3708-15.
2003: Wei Zhang; Jian-Li Liu; Anthony Meager; John Newsom-Davis; Nick Willcox
Autoantibodies to IL-12 in myasthenia gravis patients with thymoma; effects on the IFN-gamma responses of healthy CD4+ T cells.
Journal of neuroimmunology 2003;139(1-2):102-8.
2003: Anthony Meager; Meenu Wadhwa; Paula Dilger; Chris Bird; Robin Thorpe; J Newsom-Davis; Nick Willcox
Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis.
Clinical and experimental immunology 2003;132(1):128-36.
2002: Ian Matthews; Gary P Sims; Serena Ledwidge; David I Stott; David Beeson; Nick Willcox; Angela Vincent
Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen.
Laboratory investigation; a journal of technical methods and pathology 2002;82(10):1407-17.
2002: Ioannis Roxanis; Kingsley Micklem; John McConville; John Newsom-Davis; Nick Willcox
Thymic myoid cells and germinal center formation in myasthenia gravis; possible roles in pathogenesis.
Journal of neuroimmunology 2002;125(1-2):185-97.
2001: Camilla Buckley; John Newsom-Davis; Nick Willcox; Angela Vincent
Do titin and cytokine antibodies in MG patients predict thymoma or thymoma recurrence?
Neurology 2001;57(9):1579-82.
2001: Gary P Sims; Hiroyuki Shiono; Nick Willcox; David I Stott
Somatic hypermutation and selection of B cells in thymic germinal centers responding to acetylcholine receptor in myasthenia gravis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):1935-44.
2001: Camilla Buckley; D Douek; John Newsom-Davis; Angela Vincent; Nick Willcox
Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis.
Annals of neurology 2001;50(1):64-72.
2001: J Curnow; Louise Corlett; Nick Willcox; Angela Vincent
Presentation by myoblasts of an epitope from endogenous acetylcholine receptor indicates a potential role in the spreading of the immune response.
Journal of neuroimmunology 2001;115(1-2):127-34.
2001: Ioannis Roxanis; Kingsley Micklem; Nick Willcox
True epithelial hyperplasia in the thymus of early-onset myasthenia gravis patients: implications for immunopathogenesis.
Journal of neuroimmunology 2001;112(1-2):163-73.
2000: Angela Vincent; Nick Willcox
Eurojunction '99. The 5th European Conference on Myasthenia Gravis and Other Disorders of the Neuromuscular Junction. Organised by Renato Mantegazza, Ferdinando Cornelio and Klaus Toyka and their colleagues, held in Sportilia, Italy, June 1999.
European neurology 2000;43(2):123-4.
1999: M Janer; A Cowland; J Picard; D Campbell; P Pontarotti; John Newsom-Davis; Mike Bunce; K Welsh; A Demaine; A G Wilson; Nick Willcox
A susceptibility region for myasthenia gravis extending into the HLA-class I sector telomeric to HLA-C.
Human immunology 1999;60(9):909-17.
1999: Anthony Meager; Meenu Wadhwa; Chris Bird; Paula Dilger; Robin Thorpe; J Newsom-Davis; Nick Willcox
Spontaneously occurring neutralizing antibodies against granulocyte-macrophage colony-stimulating factor in patients with autoimmune disease.
Immunology 1999;97(3):526-32.
1999: M Hill; P Moss; Paul Wordsworth; John Newsom-Davis; Nick Willcox
T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes.
Journal of neuroimmunology 1999;97(1-2):146-53.
1999: H Matsuo; Louise Corlett; S Hawke; M Nicolle; P Driscoll; S Deshpande; EG Spack; Nick Willcox
Distant interactions between dimorphisms in HLA-DR4 radically affect recognition of defined peptides by a specific T cell clone.
International immunology 1999;11(5):835-43.
1999: N Nagvekar; Louise Corlett; LW Jacobson; H Matsuo; R Chalkley; P C Driscoll; S Deshpande; EG Spack; Nick Willcox
Scanning a DRB3*0101 (DR52a)-restricted epitope cross-presented by DR3: overlapping natural and artificial determinants in the human acetylcholine receptor.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):4079-87.
1999: M Hill; David Beeson; P Moss; Leslie Jacobson; A Bond; Louise Corlett; John Newsom-Davis; Angela Vincent; Nick Willcox
Early-onset myasthenia gravis: a recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a.
Annals of neurology 1999;45(2):224-31.
1999: Angela Vincent; Nick Willcox
The role of T-cells in the initiation of autoantibody responses in thymoma patients.
Pathology, research and practice 1999;195(8):535-40.
1998: Angela Vincent; Nick Willcox; M Hill; J Curnow; CA MacLennan; David Beeson
Determinant spreading and immune responses to acetylcholine receptors in myasthenia gravis.
Immunological reviews 1998;164():157-68.
1998: SJ Curnow; Nick Willcox; Angela Vincent
Induction of primary immune responses by allogeneic human myoblasts: dissection of the cell types required for proliferation, IFNgamma secretion and cytotoxicity.
Journal of neuroimmunology 1998;86(1):53-62.
1998: AM Moody; H Reyburn; Nick Willcox; John Newsom-Davis
New polymorphism of the human T-cell receptor AV28S1 gene segment.
Immunogenetics 1998;48(1):62-4.
1998: N Nagvekar; AM Moody; P Moss; Ioannis Roxanis; J Curnow; David Beeson; N Pantic; John Newsom-Davis; Angela Vincent; Nick Willcox
A pathogenetic role for the thymoma in myasthenia gravis. Autosensitization of IL-4- producing T cell clones recognizing extracellular acetylcholine receptor epitopes presented by minority class II isotypes.
The Journal of clinical investigation 1998;101(10):2268-77.
1998: Angela Vincent; Leslie Jacobson; Paul Plested; Agata Polizzi; Teresa Tang; S Riemersma; Claire Newland; S Ghorazian; J Farrar; CA MacLennan; Nick Willcox; David Beeson; John Newsom-Davis
Antibodies affecting ion channel function in acquired neuromyotonia, in seropositive and seronegative myasthenia gravis, and in antibody-mediated arthrogryposis multiplex congenita.
Annals of the New York Academy of Sciences 1998;841():482-96.
1998: Ian Matthews; Jeremy Farrar; S McLachlan; B Rapoport; John Newsom-Davis; Nick Willcox; Angela Vincent
Production of Fab fragments against the human acetylcholine receptor from myasthenia gravis thymus lambda and kappa phage libraries.
Annals of the New York Academy of Sciences 1998;841():418-21.
1998: Y Liyanage; M Teo; CA MacLennan; A Buckel; David Beeson; Nick Willcox; John Newsom-Davis; Angela Vincent
Expression of muscle proteins in thymomas of patients with myasthenia gravis.
Annals of the New York Academy of Sciences 1998;841():411-3.
1998: CA MacLennan; David Beeson; Nick Willcox; Angela Vincent; John Newsom-Davis
Muscle nicotinic acetylcholine receptor mRNA expression in hyperplastic and neoplastic myasthenia gravis thymus.
Annals of the New York Academy of Sciences 1998;841():407-10.
1998: David Beeson; A P Bond; Louise Corlett; SJ Curnow; M E Hill; LW Jacobson; CA MacLennan; Anthony Meager; AM Moody; P Moss; N Nagvekar; John Newsom-Davis; N Pantic; Ioannis Roxanis; EG Spack; Angela Vincent; Nick Willcox
Thymus, thymoma, and specific T cells in myasthenia gravis.
Annals of the New York Academy of Sciences 1998;841():371-87.
1998: N Nagvekar; LW Jacobson; Nick Willcox; Angela Vincent
Epitopes expressed in myasthenia gravis (MG) thymomas are not recognized by patients' T cells or autoantibodies.
Clinical and experimental immunology 1998;112(1):17-20.
1998: A P Bond; Louise Corlett; SJ Curnow; EG Spack; Nick Willcox; John Newsom-Davis
Diverse patterns of unresponsiveness in an acetylcholine receptor-specific T-cell clone from a myasthenia gravis patient after engaging the T-cell receptor with three different ligands.
Journal of neuroimmunology 1998;82(2):182-90.
1997: Anthony Meager; A Vincent; J Newsom-Davis; Nick Willcox
Spontaneous neutralising antibodies to interferon--alpha and interleukin-12 in thymoma-associated autoimmune disease.
Lancet 1997;350(9091):1596-7.
1997: Jeremy Farrar; S Portolano; Nick Willcox; Angela Vincent; Leslie Jacobson; John Newsom-Davis; B Rapoport; S M McLachlan
Diverse Fab specific for acetylcholine receptor epitopes from a myasthenia gravis thymus combinatorial library.
International immunology 1997;9(9):1311-8.
1997: A Bond; Louise Corlett; N Nagvekar; Leslie Jacobson; N Pantic; David Beeson; M Nicolle; Angela Vincent; John Newsom-Davis; EG Spack; Nick Willcox
Heterogeneity and immunotherapy of specific T-cells in myasthenia gravis.
Biochemical Society transactions 1997;25(2):665-70.
1996: S Hawke; H Matsuo; M Nicolle; G Malcherek; Arthur Melms; Nick Willcox
Autoimmune T cells in myasthenia gravis: heterogeneity and potential for specific immunotargeting.
Immunology today 1996;17(7):307-11.
1996: J M Heckmann; Karen E Morrison; Barbara Emeryk-Szajewska; H Strugalska; J Bergoffen; Nick Willcox; John Newsom-Davis
Human muscle acetylcholine receptor alpha-subunit gene (CHRNA1) association with autoimmune myasthenia gravis in black, mixed-ancestry and Caucasian subjects.
Journal of autoimmunity 1996;9(2):175-80.
1995: H Matsuo; A P Batocchi; S Hawke; M Nicolle; Leslie Jacobson; Angela Vincent; John Newsom-Davis; Nick Willcox
Peptide-selected T cell lines from myasthenia gravis patients and controls recognize epitopes that are not processed from whole acetylcholine receptor.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3683-92.
1995: M W Nicolle; S Hawke; Nick Willcox; Angela Vincent
Differences in processing of an autoantigen by DR4:Dw4.2 and DR4:Dw14.2 antigen-presenting cells.
European journal of immunology 1995;25(7):2119-22.
1995: N E Gilhus; M Jones; H Turley; K C Gatter; N Nagvekar; John Newsom-Davis; Nick Willcox
Oncogene proteins and proliferation antigens in thymomas: increased expression of epidermal growth factor receptor and Ki67 antigen.
Journal of clinical pathology 1995;48(5):447-55.
1995: Caroline O S Savage; Christopher J Brooks; G C Harcourt; J K Picard; W King; D M Sansom; Nick Willcox
Human vascular endothelial cells process and present autoantigen to human T cell lines.
International immunology 1995;7(3):471-9.
1995: N E Gilhus; Nick Willcox; G Harcourt; N Nagvekar; David Beeson; Angela Vincent; John Newsom-Davis
Antigen presentation by thymoma epithelial cells from myasthenia gravis patients to potentially pathogenic T cells.
Journal of neuroimmunology 1995;56(1):65-76.
1994: M W Nicolle; B Nag; S D Sharma; Nick Willcox; Angela Vincent; D J Ferguson; John Newsom-Davis
Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II-peptide complexes.
The Journal of clinical investigation 1994;93(4):1361-9.
1994: S Ratanachaiyavong; D Fleming; M Janer; Andrew G Demaine; Nick Willcox; John Newsom-Davis; Alan M McGregor
HLA-DPB1 polymorphisms in patients with hyperthyroid Graves' disease and early onset myasthenia gravis.
Autoimmunity 1994;17(2):99-104.
1993: Nick Willcox
Myasthenia gravis.
Current opinion in immunology 1993;5(6):910-7.
1993: G Harcourt; A P Batocchi; S Hawke; David Beeson; N Pantic; Leslie Jacobson; Nick Willcox; Angela Vincent; John Newsom-Davis
Detection of alpha-subunit isoforms in human muscle acetylcholine receptor by specific T cells from a myasthenia gravis patient.
Proceedings. Biological sciences / The Royal Society 1993;254(1339):1-6.
1993: F Baggi; M Nicolle; Angela Vincent; H Matsuo; Nick Willcox; John Newsom-Davis
Presentation of endogenous acetylcholine receptor epitope by an MHC class II-transfected human muscle cell line to a specific CD4+ T cell clone from a myasthenia gravis patient.
Journal of neuroimmunology 1993;46(1-2):57-65.
1993: M W Nicolle; Angela Vincent; S Sharma; B Nag; Nick Willcox; John Newsom-Davis
An in vitro model for disease-specific immunotherapy in myasthenia gravis using soluble MHC class II bound to AChR-derived peptide.
Annals of the New York Academy of Sciences 1993;681():577-80.
1993: S Hawke; Nick Willcox; G Harcourt; Angela Vincent; John Newsom-Davis
Stimulation of specific T cells by human AChR adsorbed to immunomagnetic particles.
Annals of the New York Academy of Sciences 1993;681():288-91.
1993: A P Batocchi; G Harcourt; David Beeson; N Pantic; S Hawke; Nick Willcox; John Newsom-Davis
Differential recognition by T cells of the P3A+ and P3A- isoforms of the human acetylcholine receptor alpha-subunit.
Annals of the New York Academy of Sciences 1993;681():280-2.
1993: Nick Willcox; F Baggi; A P Batocchi; David Beeson; G Harcourt; S Hawke; Leslie Jacobson; H Matsuo; A M Moody; N Nagvekar
Approaches for studying the pathogenic T cells in autoimmune patients.
Annals of the New York Academy of Sciences 1993;681():219-37.
1992: KD Pile; Nick Willcox; John I Bell; B Paul Wordsworth
A novel HLA-DR4 allele (DRB1*0414) in a patient with myasthenia gravis.
Tissue antigens 1992;40(5):264-6.
1992: S Hawke; Nick Willcox; G Harcourt; Angela Vincent; John Newsom-Davis
Stimulation of human T cells by sparse antigens captured on immunomagnetic particles.
Journal of immunological methods 1992;155(1):41-8.
1992: Andrew G Demaine; Nick Willcox; M Janer; K Welsh; John Newsom-Davis
Immunoglobulin heavy chain gene associations in myasthenia gravis: new evidence for disease heterogeneity.
Journal of neurology 1992;239(1):53-6.
1992: Nick Willcox
The third Euromyasthenia Conference; meeting report and update on myasthenia research.
Autoimmunity 1992;11(3):209-12.
1991: B Ong; Nick Willcox; P Wordsworth; David Beeson; Angela Vincent; D Altmann; J S Lanchbury; G C Harcourt; John I Bell; John Newsom-Davis
Critical role for the Val/Gly86 HLA-DR beta dimorphism in autoantigen presentation to human T cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):7343-7.
1991: Nick Willcox; M Schluep; M A Ritter; John Newsom-Davis
The thymus in seronegative myasthenia gravis patients.
Journal of neurology 1991;238(5):256-61.
1991: N Sommer; G C Harcourt; Nick Willcox; David Beeson; John Newsom-Davis
Acetylcholine receptor-reactive T lymphocytes from healthy subjects and myasthenia gravis patients.
Neurology 1991;41(8):1270-6.
1990: N Sommer; Nick Willcox; G C Harcourt; John Newsom-Davis
Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor-reactive T cells.
Annals of neurology 1990;28(3):312-9.
1989: Nick Willcox; M Schluep; N Sommer; D Campana; G Janossy; A N Brown; John Newsom-Davis
Variable corticosteroid sensitivity of thymic cortex and medullary peripheral-type lymphoid tissue in myasthenia gravis patients: structural and functional effects.
The Quarterly journal of medicine 1989;73(271):1071-87.
1989: A C Jermy; C A Fisher; Angela Vincent; Nick Willcox; John Newsom-Davis
Experimental autoimmune myasthenia gravis induced in mice without adjuvant: genetic susceptibility and adoptive transfer of weakness.
Journal of autoimmunity 1989;2(5):675-88.
1989: John Newsom-Davis; G Harcourt; N Sommer; David Beeson; Nick Willcox; J B Rothbard
T-cell reactivity in myasthenia gravis.
Journal of autoimmunity 1989;2 Suppl():101-8.
1988: F Heidenreich; Angela Vincent; Nick Willcox; John Newsom-Davis
Anti-acetylcholine receptor antibody specificities in serum and in thymic cell culture supernatants from myasthenia gravis patients.
Neurology 1988;38(11):1784-8.
1988: M Schluep; Nick Willcox; M A Ritter; John Newsom-Davis; M Larché; A N Brown
Myasthenia gravis thymus: clinical, histological and culture correlations.
Journal of autoimmunity 1988;1(5):445-67.
1988: Andrew G Demaine; Nick Willcox; K Welsh; John Newsom-Davis
Associations of the autoimmune myasthenias with genetic markers in the immunoglobulin heavy chain region.
Annals of the New York Academy of Sciences 1988;540():266-8.
1988: G Harcourt; N Sommer; J Rothbard; David Beeson; Nick Willcox; John Newsom-Davis
Blood and thymic lymphocyte responses to peptide sequences of the acetylcholine receptor in myasthenia gravis.
Annals of the New York Academy of Sciences 1988;540():354-6.
1987: M Schluep; Nick Willcox; Angela Vincent; G K Dhoot; John Newsom-Davis
Acetylcholine receptors in human thymic myoid cells in situ: an immunohistological study.
Annals of neurology 1987;22(2):212-22.
1987: Nick Willcox; M Schluep; M A Ritter; H J Schuurman; John Newsom-Davis; B Christensson
Myasthenic and nonmyasthenic thymoma. An expansion of a minor cortical epithelial cell subset?
The American journal of pathology 1987;127(3):447-60.
1987: John Newsom-Davis; Nick Willcox; M Schluep; G Harcourt; Angela Vincent; S Mossman; D Wray; J Burges
Immunological heterogeneity and cellular mechanisms in myasthenia gravis.
Annals of the New York Academy of Sciences 1987;505():12-26.
1987: Angela Vincent; P J Whiting; M Schluep; F Heidenreich; B Lang; A Roberts; Nick Willcox; John Newsom-Davis
Antibody heterogeneity and specificity in myasthenia gravis.
Annals of the New York Academy of Sciences 1987;505():106-20.
1985: Nick Willcox; A G Demaine; J Newsom-Davis; K I Welsh; S A Robb; S G Spiro
Increased frequency of IgG heavy chain marker Glm(2) and of HLA-B8 in Lambert-Eaton myasthenic syndrome with and without associated lung carcinoma.
Human immunology 1985;14(1):29-36.
1985: Nick Willcox; M Schluep; M Bofill; John Newsom-Davis
Isolation of germinal centre (GC) cells is greatly improved by using the protease dispase to prepare cell suspensions.
Advances in experimental medicine and biology 1985;186():979-84.