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Henning Willers

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Clemens Grassberger; Antony J Lomax; Noah Choi; Stephen Dowdell; James Shackleford; Greg Sharp; Henning Willers; Harald Paganetti
Motion interplay as a function of patient parameters and spot size in spot scanning proton therapy for lung cancer.
Moritz Birkelbach; Jochen Dahm-Daphi; Benedict Daly; Michael I Ebright; Natalie Ferraiolo; Liliana Gheorghiu; Lisa A Kachnic; Carl O'Hara; Heike N Pfäffle; Lecia V Sequist; Cheryl Spencer; Johnathan R Whetstine; Cyril H Benes; Lee Zou; Henning Willers
Detection of impaired homologous recombination repair in NSCLC cells and tissues.
Joao Seco; Kenneth Westover; Judith Adams; Hamid Reza Panahandeh; Henning Willers
Treatment of non-small cell lung cancer patients with proton beam-based stereotactic body radiotherapy: dosimetric comparison with photon plans highlights importance of range uncertainty.

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2013: Clemens Grassberger; Antony J Lomax; Noah Choi; Stephen Dowdell; James Shackleford; Greg Sharp; Henning Willers; Harald Paganetti
Motion interplay as a function of patient parameters and spot size in spot scanning proton therapy for lung cancer.
International journal of radiation oncology, biology, physics 2013;86(2):380-6.
2013: Moritz Birkelbach; Jochen Dahm-Daphi; Benedict Daly; Michael I Ebright; Natalie Ferraiolo; Liliana Gheorghiu; Lisa A Kachnic; Carl O'Hara; Heike N Pfäffle; Lecia V Sequist; Cheryl Spencer; Johnathan R Whetstine; Cyril H Benes; Lee Zou; Henning Willers
Detection of impaired homologous recombination repair in NSCLC cells and tissues.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013;8(3):279-86.
2012: Joao Seco; Kenneth Westover; Judith Adams; Hamid Reza Panahandeh; Henning Willers
Treatment of non-small cell lung cancer patients with proton beam-based stereotactic body radiotherapy: dosimetric comparison with photon plans highlights importance of range uncertainty.
International journal of radiation oncology, biology, physics 2012;83(1):354-61.
2012: Naokazu Chiba; Valentine Comaills; Daniel A Haber; Tetsu Hayashida; Elena F Brachtel; Toshiyuki Shimada; Bunsyo Shiotani; Ken Tajima; Fumiyuki Takahashi; Maria d M Vivanco; Henning Willers; Daniel Winokur; Lee Zou; Shyamala Maheswaran
Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(8):2760-5.
2011: Meng Wang; Michael Baumann; Cyril Benes; Jochen Dahm-Daphi; Ekkehard Dikomey; Liliana Gheorghiu; Mechthild Krause; Malte Kriegs; Fabian Morsbach; Akash Nanda; David Sander; Jeffrey Settleman; Henning Willers
EGF receptor inhibition radiosensitizes NSCLC cells by inducing senescence in cells sustaining DNA double-strand breaks.
Cancer research 2011;71(19):6261-9.
2011: Lisa A Kachnic; Li Li; Loreen Fournier; Natalie Ferraiolo; Jochen Dahm-Daphi; Kerstin Borgmann; Henning Willers
FANCD2 but not FANCA promotes cellular resistance to type II topoisomerase poisons.
Cancer letters 2011;305(1):86-93.
2011: Bianca M Sirbu; Verena Wülfing; Lee Zou; Katie E Clarkson; Jochen Dahm-Daphi; Liliana Gheorghiu; Sarah J Lachmayer; Linda W Lee; Lara M Marten; Simon Nicholas Powell; Henning Willers
ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.
PloS one 2011;6(8):e23053.
2010: April F Eichler; Kristopher T Kahle; Daphne L Wang; Victoria A Joshi; Henning Willers; Jeffrey A Engelman; Thomas J Lynch; Lecia V Sequist
EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer.
Neuro-oncology 2010;12(11):1193-9.
2010: Lisa A Kachnic; Li Li; Loreen Fournier; Henning Willers
Fanconi anemia pathway heterogeneity revealed by cisplatin and oxaliplatin treatments.
Cancer letters 2010;292(1):73-9.
2008: Akash Nanda; Dora C Dias-Santagata; Hannah Stubbs; Carl J O'Hara; Ken S Zaner; Thomas J Lynch; Henning Willers
Unusual tumor response and toxicity from radiation and concurrent erlotinib for non-small-cell lung cancer.
Clinical lung cancer 2008;9(5):285-7.
2008: Henning Willers; Lisa A Kachnic; Chen-Mei Luo; Li Li; Martin Purschke; Kerstin Borgmann; Kathryn D Held; Simon Nicholas Powell
Biomarkers and mechanisms of FANCD2 function.
Journal of biomedicine & biotechnology 2008;2008():821529.
2006: Henning Willers; J Husson; L W Lee; Petra Hubbe; F Gazemeier; Simon Nicholas Powell; Jochen Dahm-Daphi
Distinct mechanisms of nonhomologous end joining in the repair of site-directed chromosomal breaks with noncomplementary and complementary ends.
Radiation research 2006;166(4):567-74.
2006: Henning Willers; Kathryn D Held
Introduction to clinical radiation biology.
Hematology/oncology clinics of North America 2006;20(1):1-24.
2006: Jing Zhuang; Junran Zhang; Henning Willers; Hong Wang; Jay H Chung; Dik C van Gent; Dennis E Hallahan; Simon Nicholas Powell; Fang Xia
Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining.
Cancer research 2006;66(3):1401-8.
2005: Jochen Dahm-Daphi; Petra Hubbe; Fruzsina Horvath; Rafaat El-Awady; Katie E Bouffard; Simon Nicholas Powell; Henning Willers
Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wild-type p53.
Oncogene 2005;24(10):1663-72.
2004: Larisa Y Romanova; Henning Willers; Mikhail V Blagosklonny; Simon Nicholas Powell
The interaction of p53 with replication protein A mediates suppression of homologous recombination.
Oncogene 2004;23(56):9025-33.
2004: Henning Willers; Jochen Dahm-Daphi; Simon Nicholas Powell
Repair of radiation damage to DNA.
British journal of cancer 2004;90(7):1297-301.
2004: Junran Zhang; Henning Willers; Zhihui Feng; Jagadish C Ghosh; Sang Kim; David Weaver; Jay H Chung; Simon Nicholas Powell; Fang Xia
Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.
Molecular and cellular biology 2004;24(2):708-18.
2003: Herman D Suit; Henning Willers
Comment on "Tumor response to radiotherapy regulated by endothelial cell apoptosis" (I).
Science (New York, N.Y.) 2003;302(5652):1894; author reply 1894.
2002: Simon Nicholas Powell; Henning Willers; Fang Xia
BRCA2 keeps Rad51 in line. High-fidelity homologous recombination prevents breast and ovarian cancer?
Molecular cell 2002;10(6):1262-3.
2001: Henning Willers; EE McCarthy; Petra Hubbe; Jochen Dahm-Daphi; Simon Nicholas Powell
Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53.
Carcinogenesis 2001;22(11):1757-63.
2001: Fang Xia; D G Taghian; JS DeFrank; Zhao-Chong Zeng; Henning Willers; George Iliakis; Simon Nicholas Powell
Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8644-9.
2000: Henning Willers; EE McCarthy; Winfried Alberti; Jochen Dahm-Daphi; Simon Nicholas Powell
Loss of wild-type p53 function is responsible for upregulated homologous recombination in immortal rodent fibroblasts.
International journal of radiation biology 2000;76(8):1055-62.
2000: Henning Willers; EE McCarthy; B Wu; H Wunsch; W Tang; D G Taghian; Fang Xia; Simon Nicholas Powell
Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control.
Oncogene 2000;19(5):632-9.
1999: W Tang; Henning Willers; Simon Nicholas Powell
p53 directly enhances rejoining of DNA double-strand breaks with cohesive ends in gamma-irradiated mouse fibroblasts.
Cancer research 1999;59(11):2562-5.
1998: Henning Willers; HP Heilmann; Hans-Peter Beck-Bornholdt
[One hundred years of radiotherapy. Historical origins and development of fractionated irradiation in German speaking countries].
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1998;174(2):53-63.
1998: Henning Willers; F Würschmidt; H Bünemann; HP Heilmann
High-dose radiation therapy alone for inoperable non-small cell lung cancer--experience with prolonged overall treatment times.
Acta oncologica (Stockholm, Sweden) 1998;37(1):101-5.
1998: Henning Willers; C Liertz-Petersen; Hans-Hermann Dubben; Hans-Peter Beck-Bornholdt
Outcome of hyperfractionated radiation therapy in randomized clinical trials.
International journal of radiation oncology, biology, physics 1998;40(1):257-9.
1997: Hans-Peter Beck-Bornholdt; Hans-Hermann Dubben; Henning Willers
[Proliferation rate and radiosensitivity. Bergonié's and Tribondeau's error].
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1997;173(6):335-7.
1997: Henning Willers; B Prosch; Hans-Peter Beck-Bornholdt
Impact of the interfraction interval on clonogenic cell survival in split-dose irradiation of R1H rhabdomyosarcoma of the rat in vitro.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1997;43(1):93-6.
1997: Hans-Peter Beck-Bornholdt; Hans-Hermann Dubben; C Liertz-Petersen; Henning Willers
Hyperfractionation: where do we stand?
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1997;43(1):1-21.
1997: Henning Willers; F Würschmidt; I Janik; H Bünemann; HP Heilmann
[Combined breast-preserving surgery, chemotherapy and radiotherapy in the treatment of breast carcinoma. Effect of the interval between surgery and the beginning of radiotherapy].
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1997;173(3):148-54.
1997: Henning Willers; Eugen B Hug; Ira J Spiro; JT Efird; Andrew E Rosenberg; C C Wang
[Soft tissue sarcoma of the head and neck area in adults. Outcome of combined surgery and irradiation and radiotherapy alone].
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1997;173(3):131-5.
1996: Henning Willers; Hans-Peter Beck-Bornholdt
[Historical experiences in trying different overall treatment times in x-ray therapy of malignant head and neck tumors in the 1920s and 1930s].
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1996;172(9):512-5.
1996: Henning Willers; Hans-Peter Beck-Bornholdt
Origins of radiotherapy and radiobiology: separation of the influence of dose per fraction and overall treatment time on normal tissue damage by Reisner and Miescher in the 1930s.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1996;38(2):171-3.
1995: Henning Willers; Eugen B Hug; Ira J Spiro; J T Efird; Andrew E Rosenberg; Chuan-Chao Wang
Adult soft tissue sarcomas of the head and neck treated by radiation and surgery or radiation alone: patterns of failure and prognostic factors.
International journal of radiation oncology, biology, physics 1995;33(3):585-93.