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Adrian Williams

Research Profile

Physiology

Skin Absorption

Procedures

Phenomena

Concepts & Ideas

Chemicals & Drugs

Anatomy

Occupations

Chemistry, Pharmaceutical

Co-author Network

Publications

TOP 3
Clare F Rawlinson; Adrian C Williams; Peter Timmins; Ian M Grimsey
Polymer-mediated disruption of drug crystallinity.
Luciana L DeMatos; Adrian C Williams; Steven W Booth; Catherine R Petts; David J Taylor; Nicholas Blagden
Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry.
Ismaiel Tekko; Michael C Bonner; Richard D Bowen; Adrian C Williams
Permeation of bioactive constituents from Arnica montana preparations through human skin in-vitro.

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All Publications

2007: Clare F Rawlinson; Adrian C Williams; Peter Timmins; Ian M Grimsey
Polymer-mediated disruption of drug crystallinity.
International journal of pharmaceutics 2007;336(1):42-8.
2007: Luciana L DeMatos; Adrian C Williams; Steven W Booth; Catherine R Petts; David J Taylor; Nicholas Blagden
Solvent influences on metastable polymorph lifetimes: real-time interconversions using energy dispersive X-ray diffractometry.
Journal of pharmaceutical sciences 2007;96(5):1069-78.
2006: Ismaiel Tekko; Michael C Bonner; Richard D Bowen; Adrian C Williams
Permeation of bioactive constituents from Arnica montana preparations through human skin in-vitro.
The Journal of pharmacy and pharmacology 2006;58(9):1167-76.
2006: Ismaiel Tekko; Michael C Bonner; Adrian C Williams
An optimized reverse-phase high performance liquid chromatographic method for evaluating percutaneous absorption of glucosamine hydrochloride.
Journal of pharmaceutical and biomedical analysis 2006;41(2):385-92.
2006: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Can drug-bearing liposomes penetrate intact skin?
The Journal of pharmacy and pharmacology 2006;58(4):415-29.
2005: Adrian C Williams; Peter Timmins; Mingchu Lu; Robert T Forbes
Disorder and dissolution enhancement: deposition of ibuprofen on to insoluble polymers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;26(3-4):288-94.
2005: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Drug interaction and location in liposomes: correlation with polar surface areas.
International journal of pharmaceutics 2005;292(1-2):179-85.
2004: Laura E O'Brien; Peter Timmins; Adrian C Williams; Peter York
Use of in situ FT-Raman spectroscopy to study the kinetics of the transformation of carbamazepine polymorphs.
Journal of pharmaceutical and biomedical analysis 2004;36(2):335-40.
2004: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Interactions of surfactants (edge activators) and skin penetration enhancers with liposomes.
International journal of pharmaceutics 2004;276(1-2):143-61.
2004: Adrian C Williams; V Brett Cooper; Lisa Thomas; Letecia J Griffith; Catherine R Petts; Steven W Booth
Evaluation of drug physical form during granulation, tabletting and storage.
International journal of pharmaceutics 2004;275(1-2):29-39.
2004: Adrian C Williams; Brian W Barry
Penetration enhancers.
Advanced drug delivery reviews 2004;56(5):603-18.
2004: A Ahmed; Brian W Barry; Adrian C Williams; A F Davis
Penciclovir solubility in Eudragit films: a comparison of X-ray, thermal, microscopic and release rate techniques.
Journal of pharmaceutical and biomedical analysis 2004;34(5):945-56.
2002: Sarra N Campbell Roberts; Adrian C Williams; Ian M Grimsey; Steven W Booth
Quantitative analysis of mannitol polymorphs. X-ray powder diffractometry--exploring preferred orientation effects.
Journal of pharmaceutical and biomedical analysis 2002;28(6):1149-59.
2002: Sarra N Campbell Roberts; Adrian C Williams; Ian M Grimsey; Steven W Booth
Quantitative analysis of mannitol polymorphs. FT-Raman spectroscopy.
Journal of pharmaceutical and biomedical analysis 2002;28(6):1135-47.
2001: K M Mackay; Adrian C Williams; Brian W Barry
Effect of melting point of chiral terpenes on human stratum corneum uptake.
International journal of pharmaceutics 2001;228(1-2):89-97.
2001: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Skin hydration and possible shunt route penetration in controlled estradiol delivery from ultradeformable and standard liposomes.
The Journal of pharmacy and pharmacology 2001;53(10):1311-22.
2001: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Skin delivery of 5-fluorouracil from ultradeformable and standard liposomes in-vitro.
The Journal of pharmacy and pharmacology 2001;53(8):1069-77.
2001: P W Stott; Adrian C Williams; Brian W Barry
Mechanistic study into the enhanced transdermal permeation of a model beta-blocker, propranolol, by fatty acids: a melting point depression effect.
International journal of pharmaceutics 2001;219(1-2):161-76.
2000: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Skin delivery of oestradiol from lipid vesicles: importance of liposome structure.
International journal of pharmaceutics 2000;204(1-2):159-69.
2000: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Oestradiol skin delivery from ultradeformable liposomes: refinement of surfactant concentration.
International journal of pharmaceutics 2000;196(1):63-74.
1999: D J Greenhalgh; Adrian C Williams; Peter Timmins; Peter York
Solubility parameters as predictors of miscibility in solid dispersions.
Journal of pharmaceutical sciences 1999;88(11):1182-90.
1999: Gamal El Maghraby; Adrian C Williams; Brian W Barry
Skin delivery of oestradiol from deformable and traditional liposomes: mechanistic studies.
The Journal of pharmacy and pharmacology 1999;51(10):1123-34.
1999: E A Quinn; Robert T Forbes; Adrian C Williams; M J Oliver; L McKenzie; T S Purewal
Protein conformational stability in the hydrofluoroalkane propellants tetrafluoroethane and heptafluoropropane analysed by Fourier transform Raman spectroscopy.
International journal of pharmaceutics 1999;186(1):31-41.
1998: Adrian C Williams; S R Shatri; Brian W Barry
Transdermal permeation modulation by cyclodextrins: a mechanistic study.
Pharmaceutical development and technology 1998;3(3):283-96.
1998: LS Taylor; Adrian C Williams; Peter York
Particle size dependent molecular rearrangements during the dehydration of trehalose dihydrate in situ FT-Raman spectroscopy.
Pharmaceutical research 1998;15(8):1207-14.
1998: EE Lawson; A N Anigbogu; Adrian C Williams; Brian W Barry; Howell G M Edwards
Thermally induced molecular disorder in human stratum corneum lipids compared with a model phospholipid system; FT-Raman spectroscopy.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 1998;54A(3):543-58.
1998: P W Stott; Adrian C Williams; Brian W Barry
Transdermal delivery from eutectic systems: enhanced permeation of a model drug, ibuprofen.
Journal of controlled release : official journal of the Controlled Release Society 1998;50(1-3):297-308.
1998: EE Lawson; Howell G M Edwards; Brian W Barry; Adrian C Williams
Interaction of salicylic acid with verrucae assessed by FT-Raman spectroscopy.
Journal of drug targeting 1998;5(5):343-51.
1997: LS Taylor; Peter York; Adrian C Williams; V Mehta
Characterization of frozen glucose solutions.
Pharmaceutical development and technology 1997;2(4):395-402.
1996: L E McMahon; P Timmins; Adrian C Williams; Peter York
Characterization of dihydrates prepared from carbamazepine polymorphs.
Journal of pharmaceutical sciences 1996;85(10):1064-9.
1996: A N Anigbogu; Adrian C Williams; Brian W Barry
Permeation characteristics of 8-methoxypsoralen through human skin; relevance to clinical treatment.
The Journal of pharmacy and pharmacology 1996;48(4):357-66.
1995: M A Yamane; Adrian C Williams; Brian W Barry
Terpene penetration enhancers in propylene glycol/water co-solvent systems: effectiveness and mechanism of action.
The Journal of pharmacy and pharmacology 1995;47(12A):978-89.
1995: L S Taylor; Peter York; Adrian C Williams; Howell G M Edwards; V Mehta; Graham S Jackson; I G Badcoe; Anthony R Clarke
Sucrose reduces the efficiency of protein denaturation by a chaotropic agent.
Biochimica et biophysica acta 1995;1253(1):39-46.
1995: Adrian C Williams; Howell G M Edwards; Brian W Barry
The 'Iceman': molecular structure of 5200-year-old skin characterised by Raman spectroscopy and electron microscopy.
Biochimica et biophysica acta 1995;1246(1):98-105.
1994: Adrian C Williams; Brian W Barry; Howell G M Edwards
Comparison of Fourier transform Raman spectra of mammalian and reptilian skin.
The Analyst 1994;119(4):563-6.
1993: Adrian C Williams; Brian W Barry; Howell G M Edwards; Dennis W Farwell
A critical comparison of some Raman spectroscopic techniques for studies of human stratum corneum.
Pharmaceutical research 1993;10(11):1642-7.
1992: Adrian C Williams; Brian W Barry
Skin absorption enhancers.
Critical reviews in therapeutic drug carrier systems 1992;9(3-4):305-53.
1991: Adrian C Williams; Brian W Barry
Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement.
Pharmaceutical research 1991;8(1):17-24.