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David Williams

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Chemicals & Drugs

Disorders

Schistosomiasis mansoni

Living Beings

Mouse

Procedures

Phenomena

Oxidation-Reduction

Occupations

Drug Design

Co-author Network

Publications

TOP 3
Debalina Ray; David L Williams
Characterization of the phytochelatin synthase of Schistosoma mansoni.
Tolulope T Oke; Jackob Moskovitz; David L Williams
Characterization of the methionine sulfoxide reductases of Schistosoma mansoni.
Ahmed A Sayed; Anton Simeonov; Craig J Thomas; James Inglese; Christopher P Austin; David L Williams
Identification of oxadiazoles as new drug leads for the control of schistosomiasis.

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All Publications

2011: Debalina Ray; David L Williams
Characterization of the phytochelatin synthase of Schistosoma mansoni.
PLoS neglected tropical diseases 2011;5(5):e1168.
2009: Tolulope T Oke; Jackob Moskovitz; David L Williams
Characterization of the methionine sulfoxide reductases of Schistosoma mansoni.
The Journal of parasitology 2009;95(6):1421-8.
2008: Ahmed A Sayed; Anton Simeonov; Craig J Thomas; James Inglese; Christopher P Austin; David L Williams
Identification of oxadiazoles as new drug leads for the control of schistosomiasis.
Nature medicine 2008;14(4):407-12.
2007: David L Williams; Ahmed A Sayed; Jeremiah Bernier; Shanda R Birkeland; Michael J Cipriano; Alexandria R Papa; Andrew G McArthur; Andrew S Taft; Jon J Vermeire; Timothy P Yoshino
Profiling Schistosoma mansoni development using serial analysis of gene expression (SAGE).
Experimental parasitology 2007;117(3):246-58.
2007: Cynthia L Cass; Jeffrey R Johnson; Lindsay L Califf; Tao Xu; Hector J Hernandez; Miguel J Stadecker; John R Yates; David L Williams
Proteomic analysis of Schistosoma mansoni egg secretions.
Molecular and biochemical parasitology 2007;155(2):84-93.
2007: Angela N Kuntz; Elisabeth Davioud; Ahmed A Sayed; Lindsay L Califf; Jean Dessolin; Elias Arnér; David L Williams
Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.
PLoS medicine 2007;4(6):e206.
2006: David L Williams; Ahmed A Sayed; Debalina Ray; Andrew G McArthur
Schistosoma mansoni albumin, a major defense against oxidative damage, was acquired by lateral gene transfer from a mammalian host.
Molecular and biochemical parasitology 2006;150(2):359-63.
2006: Ahmed A Sayed; Shawna K Cook; David L Williams
Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets.
The Journal of biological chemistry 2006;281(25):17001-10.
2005: David L Williams; Hiroko Asahi; Tolulope T Oke; Jessica Lopes da Rosa; Miguel J Stadecker
Murine immune responses to a novel schistosome egg antigen, SmEP25.
International journal for parasitology 2005;35(8):875-82.
2004: Ahmed A Sayed; David L Williams
Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni.
The Journal of biological chemistry 2004;279(25):26159-66.
2003: Jon J Vermeire; Ahmed Osman; Philip T LoVerde; David L Williams
Characterisation of a Rho homologue of Schistosoma mansoni.
International journal for parasitology 2003;33(7):721-31.
2002: Bradley W Foulk; Gus Pappas; Yuriko Hirai; Hirohisa Hirai; David L Williams
Adenylosuccinate lyase of Schistosoma mansoni: gene structure, mRNA expression, and analysis of the predicted peptide structure of a potential chemotherapeutic target.
International journal for parasitology 2002;32(12):1487-95.
2002: Heather Alger; Ahmed A Sayed; Miguel J Stadecker; David L Williams
Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin.
International journal for parasitology 2002;32(10):1285-92.
2002: Heather Alger; David L Williams
The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase.
Molecular and biochemical parasitology 2002;121(1):129-39.
2001: David L Williams; Hiroko Asahi; Douglas Botkin; Miguel J Stadecker
Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase.
Infection and immunity 2001;69(2):1134-41.
2000: M A Kwatia; Douglas Botkin; David L Williams
Molecular and enzymatic characterization of Schistosoma mansoni thioredoxin peroxidase.
The Journal of parasitology 2000;86(5):908-15.