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Gareth Williams
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25
Pickavance, Lucy
24
Dryden, S
21
Widdowson, Peter
17
Frankish, HM
15
Harrold, Joanne
15
Wang, Q
14
Bing, Chen
14
Buckingham, RE
13
Naderali, Ebrahim
10
Arch, Jonathan
7
Cai, Xue
6
Walker, AB
6
Trayhurn, Paul
5
Doyle, PJ
5
Wilson, Shelagh
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All Publications
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2006: Harrold Joanne A; Williams Gareth
Melanocortin-4 receptors, beta-MSH and leptin: key elements in the satiety pathway.
Peptides 2006;27(2):365-71.
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2004: Naderali Ebrahim K; Fatani Sameer; Williams Gareth
Fenofibrate lowers adiposity and corrects metabolic abnormalities, but only partially restores endothelial function in dietary obese rats.
Atherosclerosis 2004;177(2):307-12.
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2004: Denis R G P; Bing C; Brocklehurst S; Harrold J A; Vernon R G; Williams G
Diurnal changes in hypothalamic neuropeptide and SOCS-3 expression: effects of lactation and relationship with serum leptin and food intake.
The Journal of endocrinology 2004;183(1):173-81.
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2004: Elliott Joanne C; Harrold Joanne A; Brodin Peter; Enquist Kerstin; Bäckman Assar; Byström Mona; Lindgren Kerstin; King Peter; Williams Gareth
Increases in melanin-concentrating hormone and MCH receptor levels in the hypothalamus of dietary-obese rats.
Brain research. Molecular brain research 2004;128(2):150-9.
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2004: Williams Gareth; Cai Xue J; Elliott Joanne C; Harrold Joanne A
Anabolic neuropeptides.
Physiology & behavior 2004;81(2):211-22.
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2004: Naderali Ebrahim K; Fatani Sameer; Williams Gareth
Chronic withdrawal of a high-palatable obesity-inducing diet completely reverses metabolic and vascular abnormalities associated with dietary-obesity in the rat.
Atherosclerosis 2004;172(1):63-9.
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2003: Harrold Joanne A; Williams Gareth
The cannabinoid system: a role in both the homeostatic and hedonic control of eating?
The British journal of nutrition 2003;90(4):729-34.
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2003: Naderali Ebrahim K; Estadella Debora; Rocha Milagros; Pickavance Lucy C; Fatani Sameer; Denis Raphael G P; Williams Gareth
A fat-enriched, glucose-enriched diet markedly attenuates adiponectin mRNA levels in rat epididymal adipose tissue.
Clinical science (London, England : 1979) 2003;105(4):403-8.
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2003: Denis R G P; Bing C; Naderali E K; Vernon R G; Williams G
Lactation modulates diurnal expression profiles of specific leptin receptor isoforms in the rat hypothalamus.
The Journal of endocrinology 2003;178(2):225-32.
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2003: Pickavance Lucy C; Widdowson Peter S; Foster John R; Williams Gareth; Wilding John P H
Chronic treatment with the thiazolidinedione, MCC-555, is associated with reductions in nitric oxide synthase activity and beta-cell apoptosis in the pancreas of the Zucker Diabetic Fatty rat.
International journal of experimental pathology 2003;84(2):83-9.
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2003: Harrold Joanne A; Widdowson Peter S; Williams Gareth
beta-MSH: a functional ligand that regulated energy homeostasis via hypothalamic MC4-R?
Peptides 2003;24(3):397-405.
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2003: Denis R G P; Williams G; Vernon R G
Regulation of serum leptin and its role in the hyperphagia of lactation in the rat.
The Journal of endocrinology 2003;176(2):193-203.
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2003: McNulty Steven J; Ur Ehud; Williams Gareth;
A randomized trial of sibutramine in the management of obese type 2 diabetic patients treated with metformin.
Diabetes care 2003;26(1):125-31.
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2002: Vernon R G; Denis R G P; Sorensen A; Williams G
Leptin and the adaptations of lactation in rodents and ruminants.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):678-85.
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2002: Gómez-Ambrosi J; Zabalegui N; Bing C; Tisdale M J; Trayhurn P; Williams G
Weight loss in tumour-bearing mice is not associated with changes in resistin gene expression in white adipose tissue.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):674-7.
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2002: Williams G; Waterhouse J; Mugarza J; Minors D; Hayden K
Therapy of circadian rhythm disorders in chronic fatigue syndrome: no symptomatic improvement with melatonin or phototherapy.
European journal of clinical investigation 2002;32(11):831-7.
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2002: Smith Sharon L; Harrold Joanne A; Williams Gareth
Diet-induced obesity increases mu opioid receptor binding in specific regions of the rat brain.
Brain research 2002;953(1-2):215-22.
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2002: Harrold Joanne A; Elliott Joanne C; King Peter J; Widdowson Peter S; Williams Gareth
Down-regulation of cannabinoid-1 (CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: a role for endogenous cannabinoids in driving appetite for palatable food?
Brain research 2002;952(2):232-8.
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2002: Bing Chen; Gomez-Ambrosi Javier; Zabalegui Natalia; Williams Gareth; Trayhurn Paul
Resistin and RELM-alpha gene expression in white adipose tissue of lactating mice.
Biochemical and biophysical research communications 2002;296(2):458-62.
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2002: Pinkney Jonathan; Williams Gareth
Ghrelin gets hungry.
Lancet 2002;359(9315):1360-1.
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2002: Cai Xue J; Liu Xiao H; Evans Martyn; Clapham John C; Wilson Shelagh; Arch Jonathan R S; Morris Richard; Williams Gareth
Orexins and feeding: special occasions or everyday occurrence?
Regulatory peptides 2002;104(1-3):1-9.
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2002: Pinkney J; Wilding J; Williams G; MacFarlane I
Hypothalamic obesity in humans: what do we know and what can be done?
Obesity reviews : an official journal of the International Association for the Study of Obesity 2002;3(1):27-34.
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2002: Bing C; Russell S T; Beckett E E; Collins P; Taylor S; Barraclough R; Tisdale M J; Williams G
Expression of uncoupling proteins-1, -2 and -3 mRNA is induced by an adenocarcinoma-derived lipid-mobilizing factor.
British journal of cancer 2002;86(4):612-8.
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2001: Naderali E K; Williams G
Effects of short-term feeding of a highly palatable diet on vascular reactivity in rats.
European journal of clinical investigation 2001;31(12):1024-8.
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2001: Bing C; Taylor S; Tisdale M J; Williams G
Cachexia in MAC16 adenocarcinoma: suppression of hunger despite normal regulation of leptin, insulin and hypothalamic neuropeptide Y.
Journal of neurochemistry 2001;79(5):1004-12.
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2001: Williams G; Bing C; Cai X J; Harrold J A; King P J; Liu X H
The hypothalamus and the control of energy homeostasis: different circuits, different purposes.
Physiology & behavior 2001;74(4-5):683-701.
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2001: Liu X H; Morris R; Spiller D; White M; Williams G
Orexin a preferentially excites glucose-sensitive neurons in the lateral hypothalamus of the rat in vitro.
Diabetes 2001;50(11):2431-7.
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2001: Naderali E K; Brown M J; Pickavance L C; Wilding J P; Doyle P J; Williams G
Dietary obesity in the rat induces endothelial dysfunction without causing insulin resistance: a possible role for triacylglycerols.
Clinical science (London, England : 1979) 2001;101(5):499-506.
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2001: Naderali E K; Pickavance L C; Wilding J P; Williams G
Diet-induced endothelial dysfunction in the rat is independent of the degree of increase in total body weight.
Clinical science (London, England : 1979) 2001;100(6):635-41.
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2001: Naderali E K; Pickavance L C; Wilding J P; Doyle P J; Williams G
Troglitazone corrects metabolic changes but not vascular dysfunction in dietary-obese rats.
European journal of pharmacology 2001;416(1-2):133-9.
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2001: Naderali E K; Smith S L; Doyle P J; Williams G
Vasorelaxant effects of oestradiols on guinea pigs: a role for gender differences.
European journal of clinical investigation 2001;31(3):215-20.
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2001: Cai X J; Denis R; Vernon R G; Clapham J C; Wilson S; Arch J R; Williams G
Food restriction selectively increases hypothalamic orexin-B levels in lactating rats.
Regulatory peptides 2001;97(2-3):163-8.
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2001: Collins P; Williams G
Drug treatment of obesity: from past failures to future successes?
British journal of clinical pharmacology 2001;51(1):13-25.
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2001: Cai X J; Evans M L; Lister C A; Leslie R A; Arch J R; Wilson S; Williams G
Hypoglycemia activates orexin neurons and selectively increases hypothalamic orexin-B levels: responses inhibited by feeding and possibly mediated by the nucleus of the solitary tract.
Diabetes 2001;50(1):105-12.
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2001: Naderali E K; Smith S L; Doyle P J; Williams G
The mechanism of resveratrol-induced vasorelaxation differs in the mesenteric resistance arteries of lean and obese rats.
Clinical science (London, England : 1979) 2001;100(1):55-60.
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2000: Williams G; Harrold J A; Cutler D J
The hypothalamus and the regulation of energy homeostasis: lifting the lid on a black box.
The Proceedings of the Nutrition Society 2000;59(3):385-96.
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2000: Harrold J A; Widdowson P S; Clapham J C; Williams G
Individual severity of dietary obesity in unselected Wistar rats: relationship with hyperphagia.
American journal of physiology. Endocrinology and metabolism 2000;279(2):E340-7.
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2000: King P J; Williams G; Doods H; Widdowson P S
Effect of a selective neuropeptide Y Y(2) receptor antagonist, BIIE0246 on neuropeptide Y release.
European journal of pharmacology 2000;396(1):R1-3.
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2000: Bing C; Brown M; King P; Collins P; Tisdale M J; Williams G
Increased gene expression of brown fat uncoupling protein (UCP)1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia.
Cancer research 2000;60(9):2405-10.
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2000: Naderali E K; Doyle P J; Williams G
Resveratrol induces vasorelaxation of mesenteric and uterine arteries from female guinea-pigs.
Clinical science (London, England : 1979) 2000;98(5):537-43.
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2000: Cai X J; Lister C A; Buckingham R E; Pickavance L; Wilding J; Arch J R; Wilson S; Williams G
Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and zucker diabetic fatty rats and effects of rosiglitazone.
Brain research. Molecular brain research 2000;77(1):131-7.
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2000: Harrold J A; Williams G; Widdowson P S
Early leptin response to a palatable diet predicts dietary obesity in rats: key role of melanocortin-4 receptors in the ventromedial hypothalamic nucleus.
Journal of neurochemistry 2000;74(3):1224-8.
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2000: King P J; Widdowson P S; Doods H; Williams G
Effect of cytokines on hypothalamic neuropeptide Y release in vitro.
Peptides 2000;21(1):143-6.
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2000: King P J; Widdowson P S; Doods H; Williams G
Regulation of neuropeptide Y release from hypothalamic slices by melanocortin-4 agonists and leptin.
Peptides 2000;21(1):45-8.
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1999: Cutler D J; Morris R; Sheridhar V; Wattam T A; Holmes S; Patel S; Arch J R; Wilson S; Buckingham R E; Evans M L; Leslie R A; Williams G
Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord.
Peptides 1999;20(12):1455-70.
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1999: Naderali E K; Walker A B; Doyle P; Williams G
Comparable vasorelaxant effects of 17alpha- and 17beta-oestradiol on rat mesenteric resistance arteries: an action independent of the oestrogen receptor.
Clinical science (London, England : 1979) 1999;97(6):649-55.
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1999: Park S; Harrold J A; Widdowson P S; Williams G
Increased binding at 5-HT(1A), 5-HT(1B), and 5-HT(2A) receptors and 5-HT transporters in diet-induced obese rats.
Brain research 1999;847(1):90-7.
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1999: Cai X J; Widdowson P S; Harrold J; Wilson S; Buckingham R E; Arch J R; Tadayyon M; Clapham J C; Wilding J; Williams G
Hypothalamic orexin expression: modulation by blood glucose and feeding.
Diabetes 1999;48(11):2132-7.
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1999: King P J; Widdowson P S; Doods H N; Williams G
Regulation of neuropeptide Y release by neuropeptide Y receptor ligands and calcium channel antagonists in hypothalamic slices.
Journal of neurochemistry 1999;73(2):641-6.
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1999: Walker A B; Chattington P D; Buckingham R E; Williams G
The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats.
Diabetes 1999;48(7):1448-53.
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1999: Williams G
Obesity and type 2 diabetes: a conflict of interests?
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23 Suppl 7():S2-4.
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1999: Dryden S; Brown M; King P; Williams G
Decreased plasma leptin levels in lean and obese Zucker rats after treatment with the serotonin reuptake inhibitor fluoxetine.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1999;31(6):363-6.
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1999: Bing C; King P; Pickavance L; Brown M; Ziegler D; Kaan E; Williams G
The effect of moxonidine on feeding and body fat in obese Zucker rats: role of hypothalamic NPY neurones.
British journal of pharmacology 1999;127(1):35-42.
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1999: Harrold J A; Williams G; Widdowson P S
Changes in hypothalamic agouti-related protein (AGRP), but not alpha-MSH or pro-opiomelanocortin concentrations in dietary-obese and food-restricted rats.
Biochemical and biophysical research communications 1999;258(3):574-7.
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1999: Dryden S; King P; Pickavance L; Doyle P; Williams G
Divergent effects of intracerebroventricular and peripheral leptin administration on feeding and hypothalamic neuropeptide Y in lean and obese (fa/fa) Zucker rats.
Clinical science (London, England : 1979) 1999;96(3):307-12.
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1999: Harrold J A; Widdowson P S; Williams G
Altered energy balance causes selective changes in melanocortin-4(MC4-R), but not melanocortin-3 (MC3-R), receptors in specific hypothalamic regions: further evidence that activation of MC4-R is a physiological inhibitor of feeding.
Diabetes 1999;48(2):267-71.
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1999: Pickavance L C; Widdowson P S; Vernon R G; Williams G
Neuropeptide Y receptor alterations in the hypothalamus of lactating rats.
Peptides 1999;20(9):1055-60.
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1999: Widdowson P S; Henderson L; Pickavance L; Buckingham R; Tadayyon M; Arch J R; Williams G
Hypothalamic NPY status during positive energy balance and the effects of the NPY antagonist, BW 1229U91, on the consumption of highly palatable energy-rich diet.
Peptides 1999;20(3):367-72.
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1998: Upton R; Widdowson P S; Ishii S; Tanaka H; Williams G
Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats treated with the thiazolidinedione, MCC-555.
British journal of pharmacology 1998;125(8):1708-14.
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1998: Pickavance L; Widdowson P S; King P; Ishii S; Tanaka H; Williams G
The development of overt diabetes in young Zucker Diabetic Fatty (ZDF) rats and the effects of chronic MCC-555 treatment.
British journal of pharmacology 1998;125(4):767-70.
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1998: Pickavance L; Tadayyon M; Williams G; Vernon R G
Lactation suppresses diurnal rhythm of serum leptin.
Biochemical and biophysical research communications 1998;248(1):196-9.
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1998: Savage M W; Mohamed-Ali V; Williams G
Suppression of post-glucose hyperinsulinaemia does not affect blood pressure in either normotensive or hypertensive subjects.
Clinical science (London, England : 1979) 1998;94(6):609-14.
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1998: Widdowson P S; Upton R; Pickavance L; Buckingham R; Tadayyon M; Arch J; Williams G
Acute hyperleptinemia does not modify insulin sensitivity in vivo in the rat.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1998;30(5):259-62.
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1998: Walker A B; Naderali E K; Chattington P D; Buckingham R E; Williams G
Differential vasoactive effects of the insulin sensitizers rosiglitazone (BRL 49653) and troglitazone on human small arteries in vitro.
Diabetes 1998;47(5):810-4.
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1998: Dryden S; Pickavance L; Tidd D; Williams G
The lack of specificity of neuropeptide Y (NPY) antisense oligodeoxynucleotides administered intracerebroventricularly in inhibiting food intake and NPY gene expression in the rat hypothalamus.
The Journal of endocrinology 1998;157(1):169-75.
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1998: Bing C; Frankish H M; Pickavance L; Wang Q; Hopkins D F; Stock M J; Williams G
Hyperphagia in cold-exposed rats is accompanied by decreased plasma leptin but unchanged hypothalamic NPY.
The American journal of physiology 1998;274(1 Pt 2):R62-8.
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1998: Dryden S; Pickavance L; Henderson L; Williams G
Hyperphagia induced by hypoglycemia in rats is independent of leptin and hypothalamic neuropeptide Y (NPY).
Peptides 1998;19(9):1549-55.
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1998: Bing C; Hopkins D; Wang Q; Frankish H; Buckingham R; Williams G
Direct stimulation of BAT thermogenesis does not affect hypothalamic neuropeptide Y.
Peptides 1998;19(1):167-70.
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1997: Dryden S; Burns S J; Frankish H M; Williams G
Increased hypothalamic neuropeptide Y concentration or hyperphagia in streptozotocin-diabetic rats are not mediated by glucocorticoids.
European journal of pharmacology 1997;340(2-3):221-5.
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1997: Widdowson P S; Buckingham R; Williams G
Distribution of [Leu31,Pro34]NPY-sensitive, BIBP3226-insensitive [125I]PYY(3-36) binding sites in rat brain: possible relationship to Y5 NPY receptors.
Brain research 1997;778(1):242-50.
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1997: Hopkins D F; Williams G
Insulin receptors are widely distributed in human brain and bind human and porcine insulin with equal affinity.
Diabetic medicine : a journal of the British Diabetic Association 1997;14(12):1044-50.
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1997: Wang Q; Dryden S; Frankish H M; Bing C; Pickavance L; Hopkins D; Buckingham R; Williams G
Increased feeding in fatty Zucker rats by the thiazolidinedione BRL 49653 (rosiglitazone) and the possible involvement of leptin and hypothalamic neuropeptide Y.
British journal of pharmacology 1997;122(7):1405-10.
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1997: Widdowson P S; Upton R; Henderson L; Buckingham R; Wilson S; Williams G
Reciprocal regional changes in brain NPY receptor density during dietary restriction and dietary-induced obesity in the rat.
Brain research 1997;774(1-2):1-10.
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1997: Widdowson P S; Upton R; Buckingham R; Arch J; Williams G
Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity.
Diabetes 1997;46(11):1782-5.
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1997: Walker A B; Dores J; Buckingham R E; Savage M W; Williams G
Impaired insulin-induced attenuation of noradrenaline-mediated vasoconstriction in insulin-resistant obese Zucker rats.
Clinical science (London, England : 1979) 1997;93(3):235-41.
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1997: Bing C; Pickavance L; Wang Q; Frankish H; Trayhurn P; Williams G
Role of hypothalamic neuropeptide Y neurons in the defective thermogenic response to acute cold exposure in fatty Zucker rats.
Neuroscience 1997;80(1):277-84.
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1997: Wang Q; Bing C; Al-Barazanji K; Mossakowaska D E; Wang X M; McBay D L; Neville W A; Taddayon M; Pickavance L; Dryden S; Thomas M E; McHale M T; Gloyer I S; Wilson S; Buckingham R; Arch J R; Trayhurn P; Williams G
Interactions between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat.
Diabetes 1997;46(3):335-41.
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1997: Walker A B; Savage M W; Dores J; Williams G
Insulin-induced attenuation of noradrenaline-mediated vasoconstriction in resistance arteries from Wistar rats is nitric oxide dependent.
Clinical science (London, England : 1979) 1997;92(2):147-52.
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1996: Williams G; Pirmohamed J; Minors D; Waterhouse J; Buchan I; Arendt J; Edwards R H
Dissociation of body-temperature and melatonin secretion circadian rhythms in patients with chronic fatigue syndrome.
Clinical physiology (Oxford, England) 1996;16(4):327-37.
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1996: Dryden S; Frankish H M; Wang Q; Williams G
Increased feeding and neuropeptide Y (NPY) but not NPY mRNA levels in the hypothalamus of the rat following central administration of the serotonin synthesis inhibitor p-chlorophenylalanine.
Brain research 1996;724(2):232-7.
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1996: Dryden S; Frankish H M; Wang Q; Pickavance L; Williams G
The serotonergic agent fluoxetine reduces neuropeptide Y levels and neuropeptide Y secretion in the hypothalamus of lean and obese rats.
Neuroscience 1996;72(2):557-66.
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1996: Pickavance L; Dryden S; Hopkins D; Bing C; Frankish H; Wang Q; Vernon R G; Williams G
Relationships between hypothalamic neuropeptide Y and food intake in the lactating rat.
Biochemical Society transactions 1996;24(2):236S.
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1996: Bing C; Wang W; Pickavance L; Williams G
The central regulation of energy homeostasis: roles of neuropeptide Y and other brain peptides.
Biochemical Society transactions 1996;24(2):559-65.
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1996: Leese G; Chattington P; Fraser W; Vora J; Edwards R; Williams G
Short-term night-shift working mimics the pituitary-adrenocortical dysfunction in chronic fatigue syndrome.
The Journal of clinical endocrinology and metabolism 1996;81(5):1867-70.
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1996: Bing C; Frankish H; Wang Q; Hopkins D; Keith J; Trayhurn P; Williams G
Dissociation of hypothalamic NPY from BAT uncoupling protein mRNA in rats exposed to 24 h thermoneutrality.
The American journal of physiology 1996;270(1 Pt 2):R111-7.
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1996: Dryden S; Wang Q; Frankish H M; Williams G
Differential effects of the 5-HT 1B/2C receptor agonist mCPP and the 5-HT1A agonist flesinoxan on hypothalamic neuropeptide Y in the rat: evidence that NPY may mediate serotonin's effects on food intake.
Peptides 1996;17(6):943-9.
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1996: Tomaszuk A; Simpson C; Williams G
Neuropeptide Y, the hypothalamus and the regulation of energy homeostasis.
Hormone research 1996;46(2):53-8.
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1996: Pickavance L; Dryden S; Hopkins D; Bing C; Frankish H; Wang Q; Vernon R G; Williams G
Relationships between hypothalamic neuropeptide Y and food intake in the lactating rat.
Peptides 1996;17(4):577-82.
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1995: Savage M W; Bodmer C W; Walker A B; Buchan I E; Masson E A; Williams G
Vascular reactivity to noradrenaline and neuropeptide Y in the streptozotocin-induced diabetic rat.
European journal of clinical investigation 1995;25(12):974-9.
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1995: Dryden S; Wang Q; Frankish H M; Pickavance L; Williams G
The serotonin (5-HT) antagonist methysergide increases neuropeptide Y (NPY) synthesis and secretion in the hypothalamus of the rat.
Brain research 1995;699(1):12-8.
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1995: McCarthy H D; Dryden S; Williams G
Interleukin-1 beta-induced anorexia and pyrexia in rat: relationship to hypothalamic neuropeptide Y.
The American journal of physiology 1995;269(5 Pt 1):E852-7.
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1995: Frankish H M; Dryden S; Wang Q; Bing C; MacFarlane I A; Williams G
Nicotine administration reduces neuropeptide Y and neuropeptide Y mRNA concentrations in the rat hypothalamus: NPY may mediate nicotine's effects on energy balance.
Brain research 1995;694(1-2):139-46.
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1995: Dryden S; Pickavance L; Frankish H M; Williams G
Increased neuropeptide Y secretion in the hypothalamic paraventricular nucleus of obese (fa/fa) Zucker rats.
Brain research 1995;690(2):185-8.
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1995: Bodmer C W; Schaper N C; Janssen M; De Leeuw P W; Williams G
Selective enhancement of alpha 2-adrenoceptor-mediated vasoconstriction in insulin-dependent diabetic patients with microalbuminuria.
Clinical science (London, England : 1979) 1995;88(4):421-6.
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1995: Cusin I; Dryden S; Wang Q; Rohner-Jeanrenaud F; Jeanrenaud B; Williams G
Effect of sustained physiological hyperinsulinaemia on hypothalamic neuropeptide Y and NPY mRNA levels in the rat.
Journal of neuroendocrinology 1995;7(3):193-7.
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1995: Benbow S J; Pryce D W; Noblett K; MacFarlane I A; Friedmann P S; Williams G
Flow motion in peripheral diabetic neuropathy.
Clinical science (London, England : 1979) 1995;88(2):191-6.
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1995: Frankish H M; Dryden S; Hopkins D; Wang Q; Williams G
Neuropeptide Y, the hypothalamus, and diabetes: insights into the central control of metabolism.
Peptides 1995;16(4):757-71.
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1994: McCarthy H D; Crowder R E; Dryden S; Williams G
Megestrol acetate stimulates food and water intake in the rat: effects on regional hypothalamic neuropeptide Y concentrations.
European journal of pharmacology 1994;265(1-2):99-102.
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1994: Bodmer C W; Masson E A; Savage M W; Benbow S; Patrick A W; Williams G
Asymptomatic peripheral nerve dysfunction and vascular reactivity in IDDM patients with and without microalbuminuria.
Diabetologia 1994;37(10):1056-61.
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1994: Benbow S J; Chan A W; Bowsher D R; Williams G; Macfarlane I A
The prediction of diabetic neuropathic plantar foot ulceration by liquid-crystal contact thermography.
Diabetes care 1994;17(8):835-9.
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1994: Bodmer C W; Valentine D T; Masson E A; Savage M W; Lake D; Williams G
Smoking attenuates the vasoconstrictor response to noradrenaline in type I diabetic patients and normal subjects: possible relevance to diabetic nephropathy.
European journal of clinical investigation 1994;24(5):331-6.
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1994: Dryden S; Frankish H; Wang Q; Williams G
Neuropeptide Y and energy balance: one way ahead for the treatment of obesity?
European journal of clinical investigation 1994;24(5):293-308.
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1994: Arora R; Dryden S; McKibbin P E; Williams G
Acute dexfenfluramine administration normalizes glucose tolerance in rats with insulin-deficient diabetes.
European journal of clinical investigation 1994;24(3):182-7.
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1994: Williams G
IDDM: long honeymoon, sweet ending.
Lancet 1994;343(8899):684-5.
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1994: Malabu U H; Dryden S; McCarthy H D; Kilpatrick A; Williams G
Effects of chronic vanadate administration in the STZ-induced diabetic rat. The antihyperglycemic action of vanadate is attributable entirely to its suppression of feeding.
Diabetes 1994;43(1):9-15.
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1994: Benbow S J; Chan A W; Bowsher D; MacFarlane I A; Williams G
A prospective study of painful symptoms, small-fibre function and peripheral vascular disease in chronic painful diabetic neuropathy.
Diabetic medicine : a journal of the British Diabetic Association 1994;11(1):17-21.
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1994: Malabu U H; Kilpatrick A; Ware M; Vernon R G; Williams G
Increased neuropeptide Y concentrations in specific hypothalamic regions of lactating rats: possible relationship to hyperphagia and adaptive changes in energy balance.
Peptides 1994;15(1):83-7.
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1994: Williams G
Management of non-insulin-dependent diabetes mellitus.
Lancet 1994;343(8889):95-100.
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1993: Savage M W; Fraser W D; Bodmer C W; Ginty A F; Gallagher J A; Robinson J; Williams G
Hypercalcaemia due to parathyroid hormone-related protein: long-term circulating levels may not reflect tumour activity.
Clinical endocrinology 1993;39(6):695-8; discussion 699.
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1993: Frankish H M; McCarthy H D; Dryden S; Kilpatrick A; Williams G
Neuropeptide Y receptor numbers are reduced in the hypothalamus of streptozotocin-diabetic and food-deprived rats: further evidence of increased activity of hypothalamic NPY-containing pathways.
Peptides 1993;14(5):941-8.
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1993: Tieszen K L; Patrick A W; Smith E; Williams G; Dornan T L
Accurate and precise blood glucose measurement in the hypoglycaemic range.
Diabetic medicine : a journal of the British Diabetic Association 1993;10(6):560-3.
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1993: Hopkins D F; Cotton S J; Williams G
Effective treatment of insulin-induced edema using ephedrine.
Diabetes care 1993;16(7):1026-8.
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1993: Dryden S; McCarthy H D; Malabu U H; Ware M; Williams G
Increased neuropeptide Y concentrations in specific hypothalamic nuclei of the rat following treatment with methysergide: evidence that NPY may mediate serotonin's effects on food intake.
Peptides 1993;14(4):791-6.
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1993: McCarthy H D; Kilpatrick A P; Trayhurn P; Williams G
Widespread increases in regional hypothalamic neuropeptide Y levels in acute cold-exposed rats.
Neuroscience 1993;54(1):127-32.
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1993: McCarthy H D; McKibbin P E; Perkins A V; Linton E A; Williams G
Alterations in hypothalamic NPY and CRF in anorexic tumor-bearing rats.
The American journal of physiology 1993;264(4 Pt 1):E638-43.
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1993: Lewis D E; Shellard L; Koeslag D G; Boer D E; McCarthy H D; McKibbin P E; Russell J C; Williams G
Intense exercise and food restriction cause similar hypothalamic neuropeptide Y increases in rats.
The American journal of physiology 1993;264(2 Pt 1):E279-84.
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1993: Malabu U H; Cotton S J; Kruszynska Y T; Williams G
Acute hyperinsulinemia increases neuropeptide Y concentrations in the hypothalamic arcuate nucleus of fasted rats.
Life sciences 1993;52(17):1407-16.
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1992: Malabu U H; McCarthy H D; McKibbin P E; Williams G
Peripheral insulin administration attenuates the increase in neuropeptide Y concentrations in the hypothalamic arcuate nucleus of fasted rats.
Peptides 1992;13(6):1097-102.
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1992: McKibbin P E; McCarthy H D; Shaw P; Williams G
Insulin deficiency is a specific stimulus to hypothalamic neuropeptide Y: a comparison of the effects of insulin replacement and food restriction in streptozocin-diabetic rats.
Peptides 1992;13(4):721-7.
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1992: Simmons K L; Williams G
Attempts to accelerate glucagon absorption: effects of adding a vasodilator and of injection using a 'sprinkler' needle.
European journal of clinical investigation 1992;22(6):434-7.
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1992: Williams G; Shellard L; Lewis D E; McKibbin P E; McCarthy H D; Koeslag D G; Russell J C
Hypothalamic neuropeptide Y disturbances in the obese (cp/cp) JCR:LA corpulent rat.
Peptides 1992;13(3):537-40.
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1992: Bodmer C W; Patrick A W; How T V; Williams G
Exaggerated sensitivity to NE-induced vasoconstriction in IDDM patients with microalbuminuria. Possible etiology and diagnostic implications.
Diabetes 1992;41(2):209-14.
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1992: McKibbin P E; Cotton S J; McCarthy H D; Williams G
The effect of dexamethasone on neuropeptide Y concentrations in specific hypothalamic regions.
Life sciences 1992;51(16):1301-7.
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1991: Williams G; McKibbin P E; McCarthy H D
Hypothalamic regulatory peptides and the regulation of food intake and energy balance: signals or noise?
The Proceedings of the Nutrition Society 1991;50(3):527-44.
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1991: McKibbin P E; Cotton S J; McMillan S; Holloway B; Mayers R; McCarthy H D; Williams G
Altered neuropeptide Y concentrations in specific hypothalamic regions of obese (fa/fa) Zucker rats. Possible relationship to obesity and neuroendocrine disturbances.
Diabetes 1991;40(11):1423-9.
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1991: Patrick A W; Bodmer C W; Tieszen K L; White M C; Williams G
Human insulin and awareness of acute hypoglycaemic symptoms in insulin-dependent diabetes.
Lancet 1991;338(8766):528-32.
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1991: Corrin S E; McCarthy H D; McKibbin P E; Williams G
Unchanged hypothalamic neuropeptide Y concentrations in hyperphagic, hypoglycemic rats: evidence for specific metabolic regulation of hypothalamic NPY.
Peptides 1991;12(3):425-30.
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1991: Rogers P; McKibbin P E; Williams G
Acute fenfluramine administration reduces neuropeptide Y concentrations in specific hypothalamic regions of the rat: possible implications for the anorectic effect of fenfluramine.
Peptides 1991;12(2):251-5.
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1991: McKibbin P E; Rogers P; Williams G
Increased neuropeptide Y concentrations in the lateral hypothalamic area of the rat after the onset of darkness: possible relevance to the circadian periodicity of feeding behavior.
Life sciences 1991;48(26):2527-33.
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1991: McCarthy H D; McKibbin P E; Holloway B; Mayers R; Williams G
Hypothalamic neuropeptide Y receptor characteristics and NPY-induced feeding responses in lean and obese Zucker rats.
Life sciences 1991;49(20):1491-7.
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1989: Williams G; Bloom S R
Regulatory peptides, the hypothalamus and diabetes.
Diabetic medicine : a journal of the British Diabetic Association 1989;6(6):472-85.
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