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LT Williams

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D Yan; Marion Wiesmann; M Rohan; Vivien Chan; AB Jefferson; L Guo; D Sakamoto; R H Caothien; J H Fuller; C Reinhard; P D Garcia; F M Randazzo; Jaime A Escobedo; Wendy J Fantl; LT Williams
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors.
T P Quinn; Scott J Soifer; K Ramer; LT Williams; Mary C Nakamura
A receptor for vascular endothelial growth factor that stimulates endothelial apoptosis.
TQ Sun; Bingwei Lu; John J Feng; C Reinhard; Yuh Nung Jan; Wendy J Fantl; LT Williams
PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.

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2001: D Yan; Marion Wiesmann; M Rohan; Vivien Chan; AB Jefferson; L Guo; D Sakamoto; R H Caothien; J H Fuller; C Reinhard; P D Garcia; F M Randazzo; Jaime A Escobedo; Wendy J Fantl; LT Williams
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):14973-8.
2001: T P Quinn; Scott J Soifer; K Ramer; LT Williams; Mary C Nakamura
A receptor for vascular endothelial growth factor that stimulates endothelial apoptosis.
Cancer research 2001;61(24):8629-37.
2001: TQ Sun; Bingwei Lu; John J Feng; C Reinhard; Yuh Nung Jan; Wendy J Fantl; LT Williams
PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.
Nature cell biology 2001;3(7):628-36.
2001: D Yan; John B Wallingford; TQ Sun; A M Nelson; C Sakanaka; C Reinhard; Richard M Harland; Wendy J Fantl; LT Williams
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3802-7.
2001: Daniel Cox; Bingwei Lu; TQ Sun; LT Williams; Yuh Nung Jan
Drosophila par-1 is required for oocyte differentiation and microtubule organization.
Current biology : CB 2001;11(2):75-87.
2000: M Haertel-Wiesmann; Y Liang; Wendy J Fantl; LT Williams
Regulation of cyclooxygenase-2 and periostin by Wnt-3 in mouse mammary epithelial cells.
The Journal of biological chemistry 2000;275(41):32046-51.
2000: C Sakanaka; TQ Sun; LT Williams
New steps in the Wnt/beta-catenin signal transduction pathway.
Recent progress in hormone research 2000;55():225-36.
1999: C Tribouley; M Wallroth; Vivien Chan; Xavier Paliard; E Fang; G Lamson; David Pot; Jaime A Escobedo; LT Williams
Characterization of a new member of the TNF family expressed on antigen presenting cells.
Biological chemistry 1999;380(12):1443-7.
1999: C Sakanaka; P Leong; L Xu; S D Harrison; LT Williams
Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12548-52.
1999: V W Chan; S Kothakota; M C Rohan; L Panganiban-Lustan; J P Gardner; M S Wachowicz; J A Winter; LT Williams
Secondary lymphoid-tissue chemokine (SLC) is chemotactic for mature dendritic cells.
Blood 1999;93(11):3610-6.
1999: C Sakanaka; LT Williams
Functional domains of axin. Importance of the C terminus as an oligomerization domain.
The Journal of biological chemistry 1999;274(20):14090-3.
1999: MD Gunn; S Kyuwa; Carmen Tam-Amersdorfer; T Kakiuchi; A Matsuzawa; LT Williams; H Nakano
Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization.
The Journal of experimental medicine 1999;189(3):451-60.
1998: A Klippel; M A Escobedo; M S Wachowicz; G Apell; T W Brown; M A Giedlin; WM Kavanaugh; LT Williams
Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation.
Molecular and cellular biology 1998;18(10):5699-711.
1998: AB Jefferson; A Klippel; LT Williams
Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain.
Oncogene 1998;16(18):2303-10.
1998: A Roulston; C Reinhard; P Amiri; LT Williams
Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha.
The Journal of biological chemistry 1998;273(17):10232-9.
1998: R Halenbeck; H MacDonald; A Roulston; T T Chen; L Conroy; LT Williams
CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45.
Current biology : CB 1998;8(9):537-40.
1998: C Sakanaka; J B Weiss; LT Williams
Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3020-3.
1998: MD Gunn; Vu N Ngo; K Mark Ansel; Eric H Ekland; Jason G Cyster; LT Williams
A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1.
Nature 1998;391(6669):799-803.
1998: MD Gunn; K Tangemann; Carmen Tam-Amersdorfer; Jason G Cyster; Steven D Rosen; LT Williams
A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):258-63.
1998: W Yu; Wendy J Fantl; G Harrowe; LT Williams
Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.
Current biology : CB 1998;8(1):56-64.
1997: JE Murphy; Sharleen Zhou; K Giese; LT Williams; Jaime A Escobedo; VJ Dwarki
Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13921-6.
1997: N Lee; H MacDonald; C Reinhard; R Halenbeck; A Roulston; T Shi; LT Williams
Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13642-7.
1997: S Kothakota; T Azuma; C Reinhard; A Klippel; J Tang; K Chu; T J McGarry; M W Kirschner; K Koths; D J Kwiatkowski; LT Williams
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis.
Science (New York, N.Y.) 1997;278(5336):294-8.
1997: M Deuter-Reinhard; G Apell; David Pot; A Klippel; LT Williams; WM Kavanaugh
SIP/SHIP inhibits Xenopus oocyte maturation induced by insulin and phosphatidylinositol 3-kinase.
Molecular and cellular biology 1997;17(5):2559-65.
1997: C Reinhard; B Shamoon; V Shyamala; LT Williams
Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.
The EMBO journal 1997;16(5):1080-92.
1997: AB Jefferson; V Auethavekiat; David Pot; LT Williams; Philip W Majerus
Signaling inositol polyphosphate-5-phosphatase. Characterization of activity and effect of GRB2 association.
The Journal of biological chemistry 1997;272(9):5983-8.
1997: E Shinbrot; X Liao; LT Williams
Isolation and characterization of the platelet-derived growth factor beta receptor promoter.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;208(2):211-9.
1997: MD Gunn; N A Nelken; X Liao; LT Williams
Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):376-83.
1997: A Klippel; WM Kavanaugh; David Pot; LT Williams
A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.
Molecular and cellular biology 1997;17(1):338-44.
1996: A Klippel; C Reinhard; WM Kavanaugh; G Apell; M A Escobedo; LT Williams
Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways.
Molecular and cellular biology 1996;16(8):4117-27.
1996: WM Kavanaugh; David Pot; S M Chin; M Deuter-Reinhard; A B Jefferson; F A Norris; F R Masiarz; L S Cousens; Philip W Majerus; LT Williams
Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2.
Current biology : CB 1996;6(4):438-45.
1996: X Liao; J A Escobedo; LT Williams
Viability of transgenic mice expressing a platelet derived growth factor (PDGF) antagonist in plasma.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 1996;44(4):139-43.
1996: G J Pronk; K Ramer; P Amiri; LT Williams
Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.
Science (New York, N.Y.) 1996;271(5250):808-10.
1996: A Kikuchi; LT Williams
Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase.
The Journal of biological chemistry 1996;271(1):588-94.
1995: K Chu; X Niu; LT Williams
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11894-8.
1995: Angus M MacNicol; A J Muslin; E L Howard; A Kikuchi; Melanie C MacNicol; LT Williams
Regulation of Raf-1-dependent signaling during early Xenopus development.
Molecular and cellular biology 1995;15(12):6686-93.
1995: K Morishita; D E Johnson; LT Williams
A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression.
The Journal of biological chemistry 1995;270(46):27948-53.
1995: WM Kavanaugh; Christoph W Turck; LT Williams
PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine.
Science (New York, N.Y.) 1995;268(5214):1177-9.
1995: Q Hu; A Klippel; A J Muslin; W J Fantl; LT Williams
Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase.
Science (New York, N.Y.) 1995;268(5207):100-2.
1995: Q Hu; D Milfay; LT Williams
Binding of NCK to SOS and activation of ras-dependent gene expression.
Molecular and cellular biology 1995;15(3):1169-74.
1994: WM Kavanaugh; LT Williams
An alternative to SH2 domains for binding tyrosine-phosphorylated proteins.
Science (New York, N.Y.) 1994;266(5192):1862-5.
1994: Y H Ma; H P Reusch; E Wilson; J A Escobedo; W J Fantl; LT Williams; Harlan E Ives
Activation of Na+/H+ exchange by platelet-derived growth factor involves phosphatidylinositol 3'-kinase and phospholipase C gamma.
The Journal of biological chemistry 1994;269(48):30734-9.
1994: S Werner; H Smola; X Liao; M T Longaker; T Krieg; P H Hofschneider; LT Williams
The function of KGF in morphogenesis of epithelium and reepithelialization of wounds.
Science (New York, N.Y.) 1994;266(5186):819-22.
1994: A Kikuchi; S D Demo; Z H Ye; Y W Chen; LT Williams
ralGDS family members interact with the effector loop of ras p21.
Molecular and cellular biology 1994;14(11):7483-91.
1994: W J Fantl; A J Muslin; A Kikuchi; J A Martin; Angus M MacNicol; R W Gross; LT Williams
Activation of Raf-1 by 14-3-3 proteins.
Nature 1994;371(6498):612-4.
1994: WM Kavanaugh; Christoph W Turck; A Klippel; LT Williams
Tyrosine 508 of the 85-kilodalton subunit of phosphatidylinositol 3-kinase is phosphorylated by the platelet-derived growth factor receptor.
Biochemistry 1994;33(36):11046-50.
1994: A Kikuchi; LT Williams
The post-translational modification of ras p21 is important for Raf-1 activation.
The Journal of biological chemistry 1994;269(31):20054-9.
1994: A J Muslin; Kevin G Peters; LT Williams
Direct activation of phospholipase C-gamma by fibroblast growth factor receptor is not required for mesoderm induction in Xenopus animal caps.
Molecular and cellular biology 1994;14(5):3006-12.
1994: A Klippel; J A Escobedo; M Hirano; LT Williams
The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity.
Molecular and cellular biology 1994;14(4):2675-85.
1994: E Shinbrot; Kevin G Peters; LT Williams
Expression of the platelet-derived growth factor beta receptor during organogenesis and tissue differentiation in the mouse embryo.
Developmental dynamics : an official publication of the American Association of Anatomists 1994;199(3):169-75.
1994: S D Demo; A Kikuchi; Kevin G Peters; Angus M MacNicol; A J Muslin; LT Williams
Signaling molecules that mediate the actions of FGF.
Princess Takamatsu symposia 1994;24():243-9.
1994: R I Clyman; Kevin G Peters; Yao Qi Chen; J Escobedo; LT Williams; Harlan E Ives; E Wilson
Phospholipase C gamma activation, phosphotidylinositol hydrolysis, and calcium mobilization are not required for FGF receptor-mediated chemotaxis.
Cell adhesion and communication 1994;1(4):333-42.
1993: A J Muslin; A Klippel; LT Williams
Phosphatidylinositol 3-kinase activity is important for progesterone-induced Xenopus oocyte maturation.
Molecular and cellular biology 1993;13(11):6661-6.
1993: H Ueno; J A Escobedo; LT Williams
Dominant-negative mutations of platelet-derived growth factor (PDGF) receptors. Inhibition of receptor function by ligand-dependent formation of heterodimers between PDGF alpha- and beta-receptors.
The Journal of biological chemistry 1993;268(30):22814-9.
1993: Kevin G Peters; C De Vries; LT Williams
Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8915-9.
1993: A Klippel; J A Escobedo; Q Hu; LT Williams
A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo.
Molecular and cellular biology 1993;13(9):5560-6.
1993: T P Quinn; Kevin G Peters; C De Vries; N Ferrara; LT Williams
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7533-7.
1993: A J Muslin; Angus M MacNicol; LT Williams
Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos.
Molecular and cellular biology 1993;13(7):4197-202.
1993: S Werner; W Weinberg; X Liao; Kevin G Peters; M Blessing; S H Yuspa; R L Weiner; LT Williams
Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.
The EMBO journal 1993;12(7):2635-43.
1993: T Satoh; W J Fantl; J A Escobedo; LT Williams; Y Kaziro
Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.
Molecular and cellular biology 1993;13(6):3706-13.
1993: Angus M MacNicol; A J Muslin; LT Williams
Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF.
Cell 1993;73(3):571-83.
1993: D E Johnson; LT Williams
Structural and functional diversity in the FGF receptor multigene family.
Advances in cancer research 1993;60():1-41.
1993: W J Fantl; D E Johnson; LT Williams
Signalling by receptor tyrosine kinases.
Annual review of biochemistry 1993;62():453-81.
1992: K R Dell; LT Williams
A novel form of fibroblast growth factor receptor 2. Alternative splicing of the third immunoglobulin-like domain confers ligand binding specificity.
The Journal of biological chemistry 1992;267(29):21225-9.
1992: M J Pazin; LT Williams
Triggering signaling cascades by receptor tyrosine kinases.
Trends in biochemical sciences 1992;17(10):374-8.
1992: Kevin G Peters; J Marie; E Wilson; Harlan E Ives; J Escobedo; M Del Rosario; D Mirda; LT Williams
Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis.
Nature 1992;358(6388):678-81.
1992: D S Duan; S Werner; LT Williams
A naturally occurring secreted form of fibroblast growth factor (FGF) receptor 1 binds basic FGF in preference over acidic FGF.
The Journal of biological chemistry 1992;267(23):16076-80.
1992: S Werner; Kevin G Peters; Michael T Longaker; F Fuller-Pace; MJ Banda; LT Williams
Large induction of keratinocyte growth factor expression in the dermis during wound healing.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):6896-900.
1992: WM Kavanaugh; A Klippel; J A Escobedo; LT Williams
Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells.
Molecular and cellular biology 1992;12(8):3415-24.
1992: W J Fantl; J A Escobedo; George Martin; Christoph W Turck; M del Rosario; F McCormick; LT Williams
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways.
Cell 1992;69(3):413-23.
1992: A Klippel; J A Escobedo; W J Fantl; LT Williams
The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor.
Molecular and cellular biology 1992;12(4):1451-9.
1992: C de Vries; J A Escobedo; H Ueno; K Houck; Napoleone Ferrara; LT Williams
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor.
Science (New York, N.Y.) 1992;255(5047):989-91.
1992: Kevin G Peters; J A Escobedo; W J Fantl; LT Williams
Interactions of PDGF and FGF receptors with cytoplasmic signaling molecules.
Cold Spring Harbor symposia on quantitative biology 1992;57():63-6.
1992: Kevin G Peters; S Werner; G Chen; LT Williams
Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse.
Development (Cambridge, England) 1992;114(1):233-43.
1992: S Werner; D S Duan; C de Vries; Kevin G Peters; D E Johnson; LT Williams
Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities.
Molecular and cellular biology 1992;12(1):82-8.
1992: D P Mirda; D Navarro; P Paz; P L Lee; L Pereira; LT Williams
The fibroblast growth factor receptor is not required for herpes simplex virus type 1 infection.
Journal of virology 1992;66(1):448-57.
1991: D E Johnson; J Lu; H Chen; S Werner; LT Williams
The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain.
Molecular and cellular biology 1991;11(9):4627-34.
1991: A J Muslin; LT Williams
Well-defined growth factors promote cardiac development in axolotl mesodermal explants.
Development (Cambridge, England) 1991;112(4):1095-101.
1991: H Ueno; H Colbert; J A Escobedo; LT Williams
Inhibition of PDGF beta receptor signal transduction by coexpression of a truncated receptor.
Science (New York, N.Y.) 1991;252(5007):844-8.
1991: J A Escobedo; S Navankasattusas; WM Kavanaugh; D Milfay; V A Fried; LT Williams
cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor.
Cell 1991;65(1):75-82.
1991: J A Escobedo; D R Kaplan; WM Kavanaugh; Christoph W Turck; LT Williams
A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine.
Molecular and cellular biology 1991;11(2):1125-32.
1991: D S Duan; M J Pazin; L J Fretto; LT Williams
A functional soluble extracellular region of the platelet-derived growth factor (PDGF) beta-receptor antagonizes PDGF-stimulated responses.
The Journal of biological chemistry 1991;266(1):413-8.
1991: Christoph W Turck; J Herrmann; J A Escobedo; LT Williams
Identification of phosphotyrosine residues during protein sequence analysis.
Peptide research 1991;4(1):36-9.
1991: LT Williams; J A Escobedo; W J Fantl; Christoph W Turck; A Klippel
Interactions of growth factor receptors with cytoplasmic signaling molecules.
Cold Spring Harbor symposia on quantitative biology 1991;56():243-50.
1990: D E Johnson; P L Lee; J Lu; LT Williams
Diverse forms of a receptor for acidic and basic fibroblast growth factors.
Molecular and cellular biology 1990;10(9):4728-36.
1990: D K Morrison; D R Kaplan; S G Rhee; LT Williams
Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex.
Molecular and cellular biology 1990;10(5):2359-66.
1990: D R Kaplan; D K Morrison; G Wong; F McCormick; LT Williams
PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex.
Cell 1990;61(1):125-33.
1990: G R Harsh; M T Keating; J A Escobedo; LT Williams
Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines.
Journal of neuro-oncology 1990;8(1):1-12.
1989: T H Vu; Gail R Martin; P Lee; D Mark; A Wang; LT Williams
Developmentally regulated use of alternative promoters creates a novel platelet-derived growth factor receptor transcript in mouse teratocarcinoma and embryonic stem cells.
Molecular and cellular biology 1989;9(10):4563-7.
1989: W J Fantl; J A Escobedo; LT Williams
Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis.
Molecular and cellular biology 1989;9(10):4473-8.
1989: D K Morrison; D R Kaplan; J A Escobedo; U R Rapp; Thomas M Roberts; LT Williams
Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor.
Cell 1989;58(4):649-57.
1989: P L Lee; D E Johnson; L S Cousens; V A Fried; LT Williams
Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor.
Science (New York, N.Y.) 1989;245(4913):57-60.
1989: M T Keating; C C Harryman; LT Williams
Platelet-derived growth factor receptor inducibility is acquired immediately after translation and does not require glycosylation.
The Journal of biological chemistry 1989;264(16):9129-32.
1989: G R Harsh; Mark L Rosenblum; LT Williams
Oncogene-related growth factors and growth factor receptors in human malignant glioma-derived cell lines.
Journal of neuro-oncology 1989;7(1):47-56.
1989: LT Williams
Signal transduction by the platelet-derived growth factor receptor.
Science (New York, N.Y.) 1989;243(4898):1564-70.
1989: Shaun R Coughlin; J A Escobedo; LT Williams
Role of phosphatidylinositol kinase in PDGF receptor signal transduction.
Science (New York, N.Y.) 1989;243(4895):1191-4.
1989: G R Harsh; WM Kavanaugh; N F Starksen; LT Williams
Cyclic AMP blocks expression of the c-sis gene in tumor cells.
Oncogene research 1989;4(1):65-73.
1988: J A Escobedo; P J Barr; LT Williams
Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor.
Molecular and cellular biology 1988;8(12):5126-31.
1988: P L Orchansky; J A Escobedo; LT Williams
Phosphatidylinositol linkage of a truncated form of the platelet-derived growth factor receptor.
The Journal of biological chemistry 1988;263(29):15159-65.
1988: M T Keating; J A Escobedo; LT Williams
Ligand activation causes a phosphorylation-dependent change in platelet-derived growth factor receptor conformation.
The Journal of biological chemistry 1988;263(26):12805-8.
1988: J A Escobedo; LT Williams
A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.
Nature 1988;335(6185):85-7.
1988: WM Kavanaugh; LT Williams; Harlan E Ives; Shaun R Coughlin
Serotonin-induced deoxyribonucleic acid synthesis in vascular smooth muscle cells involves a novel, pertussis toxin-sensitive pathway.
Molecular endocrinology (Baltimore, Md.) 1988;2(7):599-605.
1988: Robert N Taylor; LT Williams
Developmental expression of platelet-derived growth factor and its receptor in the human placenta.
Molecular endocrinology (Baltimore, Md.) 1988;2(7):627-32.
1988: WM Kavanaugh; G R Harsh; N F Starksen; C M Rocco; LT Williams
Transcriptional regulation of the A and B chain genes of platelet-derived growth factor in microvascular endothelial cells.
The Journal of biological chemistry 1988;263(17):8470-2.
1988: J A Escobedo; S Navankasatussas; L S Cousens; Shaun R Coughlin; G I Bell; LT Williams
A common PDGF receptor is activated by homodimeric A and B forms of PDGF.
Science (New York, N.Y.) 1988;240(4858):1532-4.
1988: J A Escobedo; M T Keating; Harlan E Ives; LT Williams
Platelet-derived growth factor receptors expressed by cDNA transfection couple to a diverse group of cellular responses associated with cell proliferation.
The Journal of biological chemistry 1988;263(3):1482-7.
1988: Shaun R Coughlin; P J Barr; L S Cousens; L J Fretto; LT Williams
Acidic and basic fibroblast growth factors stimulate tyrosine kinase activity in vivo.
The Journal of biological chemistry 1988;263(2):988-93.
1988: LT Williams; J A Escobedo; M T Keating; Shaun R Coughlin
Signal transduction by the platelet-derived growth factor receptor.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():455-65.
1988: Shaun R Coughlin; J A Escobedo; LT Williams
Molecular mechanisms of platelet-derived growth factor action.
Progress in clinical and biological research 1988;266():39-45.
1988: M T Keating; J A Escobedo; W J Fantl; LT Williams
Ligand activation causes a phosphorylation-dependent change in platelet-derived growth factor receptor conformation.
Transactions of the Association of American Physicians 1988;101():24-32.
1987: N F Starksen; G R Harsh; V C Gibbs; LT Williams
Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells.
The Journal of biological chemistry 1987;262(30):14381-4.
1987: LT Williams; J A Escobedo; M T Keating; Shaun R Coughlin
The stimulation of paracrine and autocrine mitogenic pathways by the platelet-derived growth factor receptor.
Journal of cellular physiology. Supplement 1987;Suppl 5():27-30.