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Mary Williams

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Anatomy

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Publications

TOP 3
Peter M Elias; Mary L Williams
Re-appraisal of current theories for the development and loss of epidermal pigmentation in hominins and modern humans.
Peter M Elias; Mary L Williams
Comment on 'does a history of eczema predict a future Basal cell carcinoma?'.
Peter M Elias; Mary L Williams; Kenneth R Feingold
Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.

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All Publications

2013: Peter M Elias; Mary L Williams
Re-appraisal of current theories for the development and loss of epidermal pigmentation in hominins and modern humans.
Journal of human evolution 2013;64(6):687-92.
2013: Peter M Elias; Mary L Williams
Comment on 'does a history of eczema predict a future Basal cell carcinoma?'.
The Journal of investigative dermatology 2013;133(6):1676-7.
2012: Peter M Elias; Mary L Williams; Kenneth R Feingold
Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.
Clinics in dermatology 2012;30(3):311-22.
2011: Peter M Elias; Amy Paller; Marina Rodriguez-Martin; Debra Crumrine; Mary L Williams
Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders.
Dermato-endocrinology 2011;3(2):100-6.
2008: Peter M Elias; Yutaka Hatano; Mary L Williams
Basis for the barrier abnormality in atopic dermatitis: outside-inside-outside pathogenic mechanisms.
The Journal of allergy and clinical immunology 2008;121(6):1337-43.
2008: Peter M Elias; Mary L Williams; Walter M Holleran; Yan J Jiang; Matthias Schmuth
Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism.
Journal of lipid research 2008;49(4):697-714.
2007: Matthias Schmuth; Robert Gruber; Peter M Elias; Mary L Williams
Ichthyosis update: towards a function-driven model of pathogenesis of the disorders of cornification and the role of corneocyte proteins in these disorders.
Advances in dermatology 2007;23():231-56.
2006: Marianne Demerjian; debra crumrine; Leonard M Milstone; Mary L Williams; Peter M Elias
Barrier dysfunction and pathogenesis of neutral lipid storage disease with ichthyosis (Chanarin-Dorfman syndrome).
The Journal of investigative dermatology 2006;126(9):2032-8.
2006: Jean-Pierre Hachem; Fredrik Wagberg; Matthias Schmuth; Debra Crumrine; Willy Lissens; Arumugam Jayakumar; Evi Houben; Theodora M Mauro; Göran Leonardsson; Maria Brattsand; Torbjörn Egelrud; Diane Roseeuw; Gary L Clayman; Kenneth R Feingold; Mary L Williams; Peter M Elias
Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome.
The Journal of investigative dermatology 2006;126(7):1609-21.
2004: David G Moskowitz; Ashley J Fowler; Melvin B Heyman; Sharon P Cohen; Debra Crumrine; Peter M Elias; Mary L Williams
Pathophysiologic basis for growth failure in children with ichthyosis: an evaluation of cutaneous ultrastructure, epidermal permeability barrier function, and energy expenditure.
The Journal of pediatrics 2004;145(1):82-92.
2004: Peter M Elias; Debra Crumrine; Ulrich Rassner; Jean-Pierre Hachem; Gopinathan K Menon; Wenyan Man; Monica Hoi Wun Choy; Laura Leypoldt; Kenneth R Feingold; Mary L Williams
Basis for abnormal desquamation and permeability barrier dysfunction in RXLI.
The Journal of investigative dermatology 2004;122(2):314-9.
2004: Ashley J Fowler; David G Moskowitz; Anthony Wong; Sharon P Cohen; Mary L Williams; Melvin B Heyman
Nutritional status and gastrointestinal structure and function in children with ichthyosis and growth failure.
Journal of pediatric gastroenterology and nutrition 2004;38(2):164-9.
2003: Jeffrey L Sugarman; Joachim W Fluhr; Ashley J Fowler; Thomas Bruckner; Thomas L Diepgen; Mary L Williams
The objective severity assessment of atopic dermatitis score: an objective measure using permeability barrier function and stratum corneum hydration with computer-assisted estimates for extent of disease.
Archives of dermatology 2003;139(11):1417-22.
2003: Mary L Williams; Peter M Elias
Enlightened therapy of the disorders of cornification.
Clinics in dermatology 2003;21(4):269-73.
2002: Sarah L Chamlin; Jack Kao; Ilona J Frieden; MARY SHEU; Ashley J Fowler; Joachim W Fluhr; Mary L Williams; Peter M Elias
Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity.
Journal of the American Academy of Dermatology 2002;47(2):198-208.
2002: Sarah L Chamlin; Shawn E Cowper; B Jack Longley; Mary L Williams
Generalized bullae in an infant.
Archives of dermatology 2002;138(6):831-6.
2002: Amy E Gilliam; Mary L Williams
Fatal septicemia in an infant with keratitis, ichthyosis, and deafness (KID) syndrome.
Pediatric dermatology 2002;19(3):232-6.
2002: László G Kömüves; Matthias Schmuth; Ashley J Fowler; Peter M Elias; Karen Hanley; Mao-Qiang Man; Arthur H Moser; Jean-Marc Lobaccaro; Mary L Williams; David J Mangelsdorf; Kenneth R Feingold
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis.
The Journal of investigative dermatology 2002;118(1):25-34.
2001: Matthias Schmuth; G Yosipovitch; Mary L Williams; F Weber; Helmut Hintner; Susana Ortiz-Urda; Klemens Rappersberger; Debra Crumrine; Kenneth R Feingold; Peter M Elias
Pathogenesis of the permeability barrier abnormality in epidermolytic hyperkeratosis.
The Journal of investigative dermatology 2001;117(4):837-47.
2001: Sarah L Chamlin; Mary L Williams
Pigmented lesions in adolescents.
Adolescent medicine (Philadelphia, Pa.) 2001;12(2):v, 195-212.
2001: Robert D Foster; Mary L Williams; A James Barkovich; William Y Hoffman; Stephen J Mathes; Ilona J Frieden
Giant congenital melanocytic nevi: the significance of neurocutaneous melanosis in neurologically asymptomatic children.
Plastic and reconstructive surgery 2001;107(4):933-41.
2001: Karen Hanley; L Wood; Dean C Ng; SS He; Peggy Lau; A Moser; Peter M Elias; Daniel David Bikle; Mary L Williams; Kenneth R Feingold
Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D.
Journal of lipid research 2001;42(3):390-8.
2000: László G Kömüves; Karen Hanley; Mao-Qiang Man; Peter M Elias; Mary L Williams; Kenneth R Feingold
Keratinocyte differentiation in hyperproliferative epidermis: topical application of PPARalpha activators restores tissue homeostasis.
The Journal of investigative dermatology 2000;115(3):361-7.
2000: László G Kömüves; Karen Hanley; Anne-Marie Lefebvre; Mao-Qiang Man; Dean C Ng; Daniel David Bikle; Mary L Williams; Peter M Elias; Johan Auwerx; Kenneth R Feingold
Stimulation of PPARalpha promotes epidermal keratinocyte differentiation in vivo.
The Journal of investigative dermatology 2000;115(3):353-60.
2000: Karen Hanley; László G Kömüves; Dean C Ng; Kristina Schoonjans; SS He; Peggy Lau; Daniel David Bikle; Mary L Williams; Peter M Elias; Johan Auwerx; Kenneth R Feingold
Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha.
The Journal of biological chemistry 2000;275(15):11484-91.
2000: Karen Hanley; Dean C Ng; SS He; Peggy Lau; K Min; Peter M Elias; Daniel David Bikle; David J Mangelsdorf; Mary L Williams; Kenneth R Feingold
Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription.
The Journal of investigative dermatology 2000;114(3):545-53.
1999: Karen Hanley; László G Kömüves; N M Bass; SS He; Y Jiang; Debra Crumrine; R Appel; M Friedman; J Bettencourt; K Min; Peter M Elias; Mary L Williams; Kenneth R Feingold
Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators.
The Journal of investigative dermatology 1999;113(5):788-95.
1999: Y C Giam; Mary L Williams; Philip E LeBoit; S J Orlow; Lawrence F Eichenfield; Ilona J Frieden
Neonatal erosions and ulcerations in giant congenital melanocytic nevi.
Pediatric dermatology 1999;16(5):354-8.
1999: László G Kömüves; Karen Hanley; Y Jiang; C Katagiri; Peter M Elias; Mary L Williams; Kenneth R Feingold
Induction of selected lipid metabolic enzymes and differentiation-linked structural proteins by air exposure in fetal rat skin explants.
The Journal of investigative dermatology 1999;112(3):303-9.
1998: Elizabeth Zettersten; Mao-Qiang Man; J Sato; Mitsuhiro Denda; A Farrell; Ruby Ghadially; Mary L Williams; Kenneth R Feingold; Peter M Elias
Recessive x-linked ichthyosis: role of cholesterol-sulfate accumulation in the barrier abnormality.
The Journal of investigative dermatology 1998;111(5):784-90.
1998: Karen Hanley; Kenneth R Feingold; László G Kömüves; Peter M Elias; L J Muglia; J A Majzoub; Mary L Williams
Glucocorticoid deficiency delays stratum corneum maturation in the fetal mouse.
The Journal of investigative dermatology 1998;111(3):440-4.
1998: László G Kömüves; Karen Hanley; Y Jiang; Peter M Elias; Mary L Williams; Kenneth R Feingold
Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development.
The Journal of investigative dermatology 1998;111(3):429-33.
1998: Sarah L Chamlin; Mary L Williams
Moles and melanoma.
Current opinion in pediatrics 1998;10(4):398-404.
1998: Peter M Elias; P Nau; Karen Hanley; C Cullander; Debra Crumrine; Graham Bench; E Sideras-Haddad; Theodora M Mauro; Mary L Williams; Kenneth R Feingold
Formation of the epidermal calcium gradient coincides with key milestones of barrier ontogenesis in the rodent.
The Journal of investigative dermatology 1998;110(4):399-404.
1998: Karen Hanley; Y Jiang; SS He; M Friedman; Peter M Elias; Daniel David Bikle; Mary L Williams; Kenneth R Feingold
Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARalpha.
The Journal of investigative dermatology 1998;110(4):368-75.
1997: Karen Hanley; U P Devaskar; S J Hicks; Y Jiang; Debra Crumrine; Peter M Elias; Mary L Williams; Kenneth R Feingold
Hypothyroidism delays fetal stratum corneum development in mice.
Pediatric research 1997;42(5):610-4.
1997: Karen Hanley; Yebin Jiang; Debra Crumrine; N M Bass; R Appel; Peter M Elias; Mary L Williams; Kenneth R Feingold
Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier.
The Journal of clinical investigation 1997;100(3):705-12.
1997: Karen Hanley; Y Jiang; C Katagiri; Kenneth R Feingold; Mary L Williams
Epidermal steroid sulfatase and cholesterol sulfotransferase are regulated during late gestation in the fetal rat.
The Journal of investigative dermatology 1997;108(6):871-5.
1997: Karen Hanley; Y Jiang; Walter M Holleran; Peter M Elias; Mary L Williams; Kenneth R Feingold
Glucosylceramide metabolism is regulated during normal and hormonally stimulated epidermal barrier development in the rat.
Journal of lipid research 1997;38(3):576-84.
1997: Karen Hanley; Y Jiang; Peter M Elias; Kenneth R Feingold; Mary L Williams
Acceleration of barrier ontogenesis in vitro through air exposure.
Pediatric research 1997;41(2):293-9.
1996: Karen Hanley; U Rassner; Y Jiang; D Vansomphone; Debra Crumrine; L Komüves; Peter M Elias; Kenneth R Feingold; Mary L Williams
Hormonal basis for the gender difference in epidermal barrier formation in the fetal rat. Acceleration by estrogen and delay by testosterone.
The Journal of clinical investigation 1996;97(11):2576-84.
1996: Mary L Williams; Timothy H McCalmont
KID versus KED: What's in a name.
Pediatric dermatology 1996;13(2):154-7.
1996: Karen Hanley; U Rassner; Peter M Elias; Mary L Williams; Kenneth R Feingold
Epidermal barrier ontogenesis: maturation in serum-free media and acceleration by glucocorticoids and thyroid hormone but not selected growth factors.
The Journal of investigative dermatology 1996;106(3):404-11.
1995: S T Hwang; Mary L Williams; Timothy H McCalmont; Ilona J Frieden
Sweet's syndrome leading to acquired cutis laxa (Marshall's syndrome) in an infant with alpha 1-antitrypsin deficiency.
Archives of dermatology 1995;131(10):1175-7.
1995: C M Hurt; Karen Hanley; Mary L Williams; Kenneth R Feingold
Cutaneous lipid synthesis during late fetal development in the rat.
Archives of dermatological research 1995;287(8):754-60.
1994: E Chen; James E Cleaver; C A Weber; Seymour Packman; A James Barkovich; Thomas K Koch; Mary L Williams; Mahin Golabi; Vera H Price
Trichothiodystrophy: clinical spectrum, central nervous system imaging, and biochemical characterization of two siblings.
The Journal of investigative dermatology 1994;103(5 Suppl):154S-158S.
1994: Ilona J Frieden; Mary L Williams; A J Barkovich
Giant congenital melanocytic nevi: brain magnetic resonance findings in neurologically asymptomatic children.
Journal of the American Academy of Dermatology 1994;31(3 Pt 1):423-9.
1994: SE Koch; Thomas K Koch; Mary L Williams
A dermatitis secondary to amino-acid deficiency in treated maple syrup urine disease.
Archives of pediatrics & adolescent medicine 1994;148(9):993-4.
1994: Mary L Williams; R Pennella
Melanoma, melanocytic nevi, and other melanoma risk factors in children.
The Journal of pediatrics 1994;124(6):833-45.
1994: A James Barkovich; Ilona J Frieden; Mary L Williams
MR of neurocutaneous melanosis.
AJNR. American journal of neuroradiology 1994;15(5):859-67.
1994: S Emami; Karen Hanley; N B Esterly; N Daniallinia; Mary L Williams
X-linked dominant ichthyosis with peroxisomal deficiency. An ultrastructural and ultracytochemical study of the Conradi-Hünermann syndrome and its murine homologue, the bare patches mouse.
Archives of dermatology 1994;130(3):325-36.
1993: Michelle Aszterbaum; Kenneth R Feingold; G K Menon; Mary L Williams
Glucocorticoids accelerate fetal maturation of the epidermal permeability barrier in the rat.
The Journal of clinical investigation 1993;91(6):2703-8.
1993: Mary L Williams; Michelle Aszterbaum; G K Menon; A H Moser; Kenneth R Feingold; Steven Hoath
Preservation of permeability barrier ontogenesis in the intrauterine growth-retarded fetal rat.
Pediatric research 1993;33(4 Pt 1):418-24.
1993: SE Koch; Seymour Packman; Thomas K Koch; Mary L Williams
Dermatitis in treated maple syrup urine disease.
Journal of the American Academy of Dermatology 1993;28(2 Pt 2):289-92.
1992: Mary L Williams
Ichthyosis: mechanisms of disease.
Pediatric dermatology 1992;9(4):365-8.
1992: Ruby Ghadially; Mary L Williams; S Y Hou; Peter M Elias
Membrane structural abnormalities in the stratum corneum of the autosomal recessive ichthyoses.
The Journal of investigative dermatology 1992;99(6):755-63.
1992: M Límová; Barbara M Egbert; Mary L Williams
A nodule on the side of the neck in a child. Branchial cleft cyst.
Archives of dermatology 1992;128(10):1397, 1400.
1992: S Emami; W B Rizzo; Karen Hanley; J M Taylor; M E Goldyne; Mary L Williams
Peroxisomal abnormality in fibroblasts from involved skin of CHILD syndrome. Case study and review of peroxisomal disorders in relation to skin disease.
Archives of dermatology 1992;128(9):1213-22.
1992: Mary L Williams; J S Vogel; Ruby Ghadially; Barbara E Brown; Peter M Elias
Exogenous origin of n-alkanes in pathologic scale.
Archives of dermatology 1992;128(8):1065-71.
1992: Mary L Williams
Epidermal lipids and scaling diseases of the skin.
Seminars in dermatology 1992;11(2):169-75.
1992: G K Menon; Ruby Ghadially; Mary L Williams; Peter M Elias
Lamellar bodies as delivery systems of hydrolytic enzymes: implications for normal and abnormal desquamation.
The British journal of dermatology 1992;126(4):337-45.
1992: Michelle Aszterbaum; G K Menon; Kenneth R Feingold; Mary L Williams
Ontogeny of the epidermal barrier to water loss in the rat: correlation of function with stratum corneum structure and lipid content.
Pediatric research 1992;31(4 Pt 1):308-17.
1992: Mary L Williams; G K Menon; K P Hanley
HMG-CoA reductase inhibitors perturb fatty acid metabolism and induce peroxisomes in keratinocytes.
Journal of lipid research 1992;33(2):193-208.
1991: Mary L Williams; Rosalind A Coleman; D Placezk; C Grunfeld
Neutral lipid storage disease: a possible functional defect in phospholipid- linked triacylglycerol metabolism.
Biochimica et biophysica acta 1991;1096(2):162-9.
1991: M E Goldyne; K L Blacker; Mary L Williams
Keratinocytes can regulate prostaglandin synthesis by fibroblasts: potential role for interleukin 1.
Advances in experimental medicine and biology 1991;314():317-27.
1991: Mary L Williams
Lipids in normal and pathological desquamation.
Advances in lipid research 1991;24():211-62.
1990: Walter M Holleran; Mary L Williams; W N Gao; Peter M Elias
Serine-palmitoyl transferase activity in cultured human keratinocytes.
Journal of lipid research 1990;31(9):1655-61.
1990: Peter M Elias; Mary L Williams; S J Rehfeld
N-alkanes in the skin. Function or fancy?
Archives of dermatology 1990;126(7):868-70.
1989: Mary L Williams; R W Sagebiel
Sunburns, melanoma, and the pediatrician.
Pediatrics 1989;84(2):381-2.
1989: M E Goldyne; Mary L Williams
CHILD syndrome. Phenotypic dichotomy in eicosanoid metabolism and proliferative rates among cultured dermal fibroblasts.
The Journal of clinical investigation 1989;84(1):357-60.
1989: N Y Schürer; D J Monger; M Hincenbergs; Mary L Williams
Fatty acid metabolism in human keratinocytes cultivated at an air-medium interface.
The Journal of investigative dermatology 1989;92(2):196-202.
1988: S J Rehfeld; W Z Plachy; Mary L Williams; Peter M Elias
Calorimetric and electron spin resonance examination of lipid phase transitions in human stratum corneum: molecular basis for normal cohesion and abnormal desquamation in recessive X-linked ichthyosis.
The Journal of investigative dermatology 1988;91(5):499-505.
1988: Mary L Williams; M Hincenbergs; K A Holbrook
Skin lipid content during early fetal development.
The Journal of investigative dermatology 1988;91(3):263-8.
1988: Mary L Williams; B E Brown; D J Monger; S Grayson; Peter M Elias
Lipid content and metabolism of human keratinocyte cultures grown at the air-medium interface.
Journal of cellular physiology 1988;136(1):103-10.
1988: Mary L Williams; S L Rutherford; M Ponec; M Hincenbergs; D R Placzek; Peter M Elias
Density-dependent variations in the lipid content and metabolism of cultured human keratinocytes.
The Journal of investigative dermatology 1988;91(1):86-91.
1988: D J Monger; Mary L Williams; Kenneth R Feingold; B E Brown; Peter M Elias
Localization of sites of lipid biosynthesis in mammalian epidermis.
Journal of lipid research 1988;29(5):603-12.
1988: Philip E LeBoit; E A Abel; Michael L Cleary; R T Hoppe; Mary L Williams; G S Wood; Tristam PARSLOW
Clonal rearrangement of the T cell receptor beta gene in the circulating lymphocytes of erythrodermic follicular mucinosis.
Blood 1988;71(5):1329-33.
1988: Mary L Williams; D J Monger; S L Rutherford; M Hincenbergs; S J Rehfeld; C Grunfeld
Neutral lipid storage disease with ichthyosis: lipid content and metabolism of fibroblasts.
Journal of inherited metabolic disease 1988;11(2):131-43.
1987: K L Blacker; Mary L Williams; M Goldyne
Mitomycin C-treated 3T3 fibroblasts used as feeder layers for human keratinocyte culture retain the capacity to generate eicosanoids.
The Journal of investigative dermatology 1987;89(6):536-9.
1987: Mary L Williams; Kenneth R Feingold; G Grubauer; Peter M Elias
Ichthyosis induced by cholesterol-lowering drugs. Implications for epidermal cholesterol homeostasis.
Archives of dermatology 1987;123(11):1535-8.
1987: SE Koch; Herschel S Zackheim; Mary L Williams; V Fletcher; Philip E LeBoit
Mycosis fungoides beginning in childhood and adolescence.
Journal of the American Academy of Dermatology 1987;17(4):563-70.
1987: Mary L Williams; A M Mommaas-Kienhuis; S L Rutherford; S Grayson; Bert-Jan Vermeer; Peter M Elias
Free sterol metabolism and low density lipoprotein receptor expression as differentiation markers of cultured human keratinocytes.
Journal of cellular physiology 1987;132(3):428-40.
1984: Peter M Elias; Mary L Williams; M E Maloney; J A Bonifas; B E Brown; S Grayson; Ervin H Epstein
Stratum corneum lipids in disorders of cornification. Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis.
The Journal of clinical investigation 1984;74(4):1414-21.