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Nigel Williams

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Kate Langley; Joanna Martin; Michael O'Donovan; Michael J Owen; Evangelia Stergiakouli; Sharifah Shameem Agha; Charlotte Davies; Peter Holmans; Nigel Williams; Anita Thapar
Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants.
Masashi Ikeda; Nigel Williams; Hywel J Williams; Rhodri Smith; Stephen Monks; Michael J Owen; Kieran C Murphy; Michael C O'Donovan
Failure to confirm association between PIK4CA and psychosis in 22q11.2 deletion syndrome.
Stanley Zammit; Gillian Spurlock; Hywel Williams; Nadine Norton; Nigel Williams; Michael C O'Donovan; Michael J Owen
Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use.

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All Publications

2011: Kate Langley; Joanna Martin; Michael O'Donovan; Michael J Owen; Evangelia Stergiakouli; Sharifah Shameem Agha; Charlotte Davies; Peter Holmans; Nigel Williams; Anita Thapar
Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants.
The British journal of psychiatry : the journal of mental science 2011;199(5):398-403.
2010: Masashi Ikeda; Nigel Williams; Hywel J Williams; Rhodri Smith; Stephen Monks; Michael J Owen; Kieran C Murphy; Michael C O'Donovan
Failure to confirm association between PIK4CA and psychosis in 22q11.2 deletion syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(4):980-2.
2007: Stanley Zammit; Gillian Spurlock; Hywel Williams; Nadine Norton; Nigel Williams; Michael C O'Donovan; Michael J Owen
Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use.
The British journal of psychiatry : the journal of mental science 2007;191():402-7.
2006: Beate Glaser; Valentina Moskvina; George Kirov; Kieran C Murphy; Hywel Williams; Nigel Williams; Michael J Owen; Michael C O'Donovan
Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility.
Schizophrenia research 2006;87(1-3):21-7.
2006: Lyudmila Georgieva; Valentina Moskvina; Tim Peirce; Nadine Norton; Nicholas J Bray; Lesley Jones; Peter Holmans; Stuart Macgregor; Stanley Zammit; Jennifer Wilkinson; Hywel Williams; Ivan Nikolov; Nigel Williams; Dobril Ivanov; Kenneth L Davis; Vahram Haroutunian; Joseph Buxbaum; Nick Craddock; George Kirov; Michael J Owen; Michael C O'Donovan
Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12469-74.
2005: Marian Hamshere; Philip Bennett; Nigel Williams; Ricardo Segurado; Alastair G Cardno; Nadine Norton; David Lambert; Hywel Williams; George Kirov; Aiden Corvin; Peter Holmans; Lisa Jones; Ian Jones; Michael Gill; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13.
Archives of general psychiatry 2005;62(10):1081-8.
2005: Elaine K Green; Rachel Raybould; Stuart Macgregor; Katherine Gordon-Smith; Jessica Heron; Sally Hyde; Detelina Grozeva; Marian Hamshere; Nigel Williams; Michael J Owen; Michael C O'Donovan; Lisa Jones; Ian Jones; George Kirov; Nick Craddock
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder.
Archives of general psychiatry 2005;62(6):642-8.
2005: Peter Holmans; Marian Hamshere; Paul Hollingworth; Frances Rice; Nigel Tunstall; Sue Jones; Pamela Moore; Fabienne Wavrant DeVrieze; Amanda Myers; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Michael O'Donovan; Lesley Jones; John Hardy; Alison Goate; Simon Lovestone; Michael J Owen; Julie Williams
Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;135B(1):24-32.
2005: Rachel Raybould; Elaine K Green; Stuart Macgregor; Katherine Gordon-Smith; Jessica Heron; Sally Hyde; Sian Caesar; Ivan Nikolov; Nigel Williams; Lisa Jones; Michael C O'Donovan; Michael J Owen; Ian Jones; George Kirov; Nick Craddock
Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).
Biological psychiatry 2005;57(7):696-701.
2005: Valentina Moskvina; Nadine Norton; Nigel Williams; Peter Holmans; Michael J Owen; Michael O'Donovan
Streamlined analysis of pooled genotype data in SNP-based association studies.
Genetic epidemiology 2005;28(3):273-82.
2004: Derek W Morris; D Ivanov; L Robinson; Nigel Williams; J Stevenson; Michael J Owen; Julie Williams; Michael C O'Donovan
Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;129B(1):97-103.
2004: Darko Turic; Kate Langley; Sophie Mills; M Stephens; Deborah Lawson; C Govan; Nigel Williams; Marianne B M van den Bree; Nick Craddock; Lindsey Kent; Michael J Owen; Michael O'Donovan; Anita Thapar
Follow-up of genetic linkage findings on chromosome 16p13: evidence of association of N-methyl-D aspartate glutamate receptor 2A gene polymorphism with ADHD.
Molecular psychiatry 2004;9(2):169-73.
2003: George Kirov; Lyudmila Georgieva; Nigel Williams; Ivan Nikolov; Nadine Norton; Draga Toncheva; Michael O'Donovan; Michael J Owen
Variation in the protocadherin gamma A gene cluster.
Genomics 2003;82(4):433-40.
2003: Hywel J Williams; Nigel Williams; Gillian Spurlock; Nadine Norton; Dobril Ivanov; Robin G McCreadie; Anna Preece; Val Sharkey; Sue Jones; Stanley Zammit; Ivan Nikolov; I Kehaiov; Anita Thapar; Kieran C Murphy; George Kirov; Michael J Owen; Michael C O'Donovan
Association between PRODH and schizophrenia is not confirmed.
Molecular psychiatry 2003;8(7):644-5.
2003: Hywel J Williams; Nigel Williams; Gillian Spurlock; Nadine Norton; Stanley Zammit; George Kirov; Michael J Owen; Michael C O'Donovan
Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;120B(1):42-6.
2003: Darko Turic; L Robinson; M Duke; Derek W Morris; V Webb; Marian Hamshere; Charis Milham; Elizabeth Hopkin; K Pound; S Fernando; A Grierson; M Easton; Nigel Williams; Marianne B M van den Bree; R Chowdhury; J Gruen; J Stevenson; Michael Krawczak; Michael J Owen; Michael C O'Donovan; Julie Williams
Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22.
Molecular psychiatry 2003;8(2):176-85.
2002: Amanda Myers; Fabienne Wavrant De-Vrieze; Peter Holmans; Marian Hamshere; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Heather Knowles; John C Morris; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Frances Rice; Peter Giles; Nigel Tunstall; Lesley Jones; Simon Lovestone; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Full genome screen for Alzheimer disease: stage II analysis.
American journal of medical genetics 2002;114(2):235-44.
2002: R J Anney; Mark I Rees; E Bryan; Gillian Spurlock; Nigel Williams; Nadine Norton; Hywel Williams; Alastair G Cardno; Stanley Zammit; Sue Jones; G Jones; Bastiaan Hoogendoorn; Kaye Smith; Marian Hamshere; S Coleman; Carol Guy; Michael C O'Donovan; Michael J Owen; Paul R Buckland
Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 2002;7(5):493-502.
2002: Philip Bennett; Ricardo Segurado; Ian Jones; S Bort; Fiona McCandless; David Lambert; Jessica Heron; C Comerford; Fiona Middle; Aiden Corvin; G Pelios; George Kirov; B Larsen; T Mulcahy; Nigel Williams; R O'Connell; E O'Mahony; A Payne; Michael J Owen; Peter Holmans; Nick Craddock; Michael Gill
The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report.
Molecular psychiatry 2002;7(2):189-200.
2000: Bastiaan Hoogendoorn; Nadine Norton; George Kirov; Nigel Williams; Marian Hamshere; Gillian Spurlock; J Austin; M K Stephens; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.
Human genetics 2000;107(5):488-93.
2000: J Austin; Paul R Buckland; Alastair G Cardno; Nigel Williams; Gillian Spurlock; Bastiaan Hoogendoorn; Stanley Zammit; G Jones; R Sanders; Lesley Jones; G McCarthy; Sue Jones; Nicholas J Bray; Peter McGuffin; Michael J Owen; Michael C O'Donovan
The high affinity neurotensin receptor gene (NTSR1): comparative sequencing and association studies in schizophrenia.
Molecular psychiatry 2000;5(5):552-7.
2000: Derek W Morris; L Robinson; Darko Turic; M Duke; V Webb; Charis Milham; Elizabeth Hopkin; K Pound; S Fernando; M Easton; Marian Hamshere; Nigel Williams; Peter McGuffin; J Stevenson; Michael Krawczak; Michael J Owen; Michael C O'Donovan; Julie Williams
Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q.
Human molecular genetics 2000;9(5):843-8.
2000: J Austin; Bastiaan Hoogendoorn; Paul R Buckland; Ian Jones; Fiona McCandless; Nigel Williams; Fiona Middle; Michael J Owen; Nick Craddock; Michael C O'Donovan
Association analysis of the proneurotensin gene and bipolar disorder.
Psychiatric genetics 2000;10(1):51-4.
2000: J Austin; Bastiaan Hoogendoorn; Paul R Buckland; G Speight; Alastair G Cardno; Timothy Bowen; Nigel Williams; Gillian Spurlock; R Sanders; Lesley Jones; K Murphy; G McCarthy; Peter McGuffin; Michael J Owen; Michael C O'Donovan
Comparative sequencing of the proneurotensin gene and association studies in schizophrenia.
Molecular psychiatry 2000;5(2):208-12.
2000: George Kirov; Nigel Williams; P Sham; Nick Craddock; Michael J Owen
Pooled genotyping of microsatellite markers in parent-offspring trios.
Genome research 2000;10(1):105-15.
1999: Carol A Guy; Timothy Bowen; Nigel Williams; Ian Richard Jones; Fiona McCandless; Peter McGuffin; Michael J Owen; Nick Craddock; Michael C O'Donovan
No association between a polymorphic CAG repeat in the human potassium channel gene hKCa3 and bipolar disorder.
American journal of medical genetics 1999;88(1):57-60.
1999: Pat Kehoe; Fabienne Wavrant De-Vrieze; Richard Crook; W S Wu; Peter Holmans; Iain Fenton; Gillian Spurlock; Nadine Norton; Hywel Williams; Nigel Williams; Simon Lovestone; Jordi Perez-Tur; Michael Hutton; Marie-Christine Chartier-Harlin; Shantia Shears; K Roehl; Jeremy Booth; W Van Voorst; Dzanan Ramic; Julie Williams; Alison Goate; John Hardy; Michael J Owen
A full genome scan for late onset Alzheimer's disease.
Human molecular genetics 1999;8(2):237-45.
1999: Bastiaan Hoogendoorn; Michael J Owen; PJ Oefner; Nigel Williams; J Austin; Michael C O'Donovan
Genotyping single nucleotide polymorphisms by primer extension and high performance liquid chromatography.
Human genetics 1999;104(1):89-93.
1998: W S Wu; Peter Holmans; F Wavrant-DeVrièze; Shantia Shears; Pat Kehoe; Richard Crook; Jeremy Booth; Nigel Williams; Jordi Pérez-Tur; K Roehl; Iain Fenton; Marie-Christine Chartier-Harlin; Simon Lovestone; Julie Williams; Michael Hutton; John Hardy; Michael J Owen; Alison Goate
Genetic studies on chromosome 12 in late-onset Alzheimer disease.
JAMA : the journal of the American Medical Association 1998;280(7):619-22.
1998: Philip Asherson; R Mant; Nigel Williams; Alastair G Cardno; Lesley Jones; K Murphy; DA Collier; S Nanko; Nick Craddock; S Morris; Walter Muir; B Blackwood; Peter McGuffin; Michael J Owen
A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder.
Molecular psychiatry 1998;3(4):310-20.
1996: Nick Craddock; J Daniels; Peter Holmans; Nigel Williams; Michael J Owen
Increasing the efficiency of genomic searches for linkage in complex disorders by DNA pooling of affected sib-pairs.
Molecular psychiatry 1996;1(1):59-64.