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Paul Williams

Research Profile

Living Beings

Anatomy

Disorders

Physiology

Bone Resorption

Chemicals & Drugs

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Neoplasm Transplantation

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Publications

TOP 3
Md M Rahman; Paul J Williams; Ganesh V Halade; Gabriel Fernandes
t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity.
Ganesh V Halade; Paul J Williams; Merry Lindsey; Gabriel Fernandes
Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging mice.
Ganesh V Halade; Amina El Jamali; Paul J Williams; Roberto J Fajardo; Gabriel Fernandes
Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice.

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All Publications

2011: Md M Rahman; Paul J Williams; Ganesh V Halade; Gabriel Fernandes
t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity.
Journal of cellular physiology 2011;226(9):2406-14.
2011: Ganesh V Halade; Paul J Williams; Merry Lindsey; Gabriel Fernandes
Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging mice.
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;63(4):300-7.
2011: Ganesh V Halade; Amina El Jamali; Paul J Williams; Roberto J Fajardo; Gabriel Fernandes
Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice.
Experimental gerontology 2011;46(1):43-52.
2010: Ganesh V Halade; Md M Rahman; Paul J Williams; Gabriel Fernandes
High fat diet-induced animal model of age-associated obesity and osteoporosis.
The Journal of nutritional biochemistry 2010;21(12):1162-9.
2007: Babatunde Oyajobi; Steve Muñoz; Rami Kakonen; Paul J Williams; Anjana Gupta; Christi L Wideman; Beryl Story; Barry Grubbs; Allison Armstrong; William C Dougall; I Ross Garrett; Gregory R Mundy
Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging.
Molecular cancer therapeutics 2007;6(6):1701-8.
2004: Yoshihisa Mori; Nobuaki Shimizu; Mark Dallas; Maryla Niewolna; Beryl Story; Paul J Williams; Gregory R Mundy; Toshiyuki Yoneda
Anti-alpha4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis.
Blood 2004;104(7):2149-54.
2004: Toru Hiraga; Paul J Williams; Akimi Ueda; Daisuke Tamura; Toshiyuki Yoneda
Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(13):4559-67.
2003: Toru Hiraga; Akimi Ueda; Daisuke Tamura; Kenji Hata; Fumiyo Ikeda; Paul J Williams; Toshiyuki Yoneda
Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer.
International journal of cancer. Journal international du cancer 2003;106(6):973-9.
2003: Akira Myoui; Riko Nishimura; Paul J Williams; Toru Hiraga; Daisuke Tamura; Toshimi Michigami; Gregory R Mundy; Toshiyuki Yoneda
C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis.
Cancer research 2003;63(16):5028-33.
2003: Babatunde Oyajobi; Giovanni Franchin; Paul J Williams; Donna Pulkrabek; Anjana Gupta; Steve Munoz; Barry Grubbs; Ming Zhao; Di Chen; Barbara Sherry; Gregory R Mundy
Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease.
Blood 2003;102(1):311-9.
2002: Toshimi Michigami; Toru Hiraga; Paul J Williams; Maryla Niewolna; Riko Nishimura; Gregory R Mundy; Toshiyuki Yoneda
The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs.
Breast cancer research and treatment 2002;75(3):249-58.
2002: Bing Yi; Paul J Williams; Maryla Niewolna; Yakun Wang; Toshiyuki Yoneda
Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer.
Cancer research 2002;62(3):917-23.
2001: Toshiyuki Yoneda; Paul J Williams; Toru Hiraga; Maryla Niewolna; Riko Nishimura
A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(8):1486-95.
2001: Toru Hiraga; Paul J Williams; Gregory R Mundy; Toshiyuki Yoneda
The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases.
Cancer research 2001;61(11):4418-24.
2001: Babatunde Oyajobi; D M Anderson; K Traianedes; Paul J Williams; Toshiyuki Yoneda; Gregory R Mundy
Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia of malignancy.
Cancer research 2001;61(6):2572-8.
2000: Toshimi Michigami; N Shimizu; Paul J Williams; Maryla Niewolna; Sarah L Dallas; Gregory R Mundy; Toshiyuki Yoneda
Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity.
Blood 2000;96(5):1953-60.
2000: Toshiyuki Yoneda; Toshimi Michigami; Bing Yi; Paul J Williams; Maryla Niewolna; Toru Hiraga
Actions of bisphosphonate on bone metastasis in animal models of breast carcinoma.
Cancer 2000;88(12 Suppl):2979-88.
1999: Toshiyuki Yoneda; Toshimi Michigami; Bing Yi; Paul J Williams; Maryla Niewolna; Toru Hiraga
Use of bisphosphonates for the treatment of bone metastasis in experimental animal models.
Cancer treatment reviews 1999;25(5):293-9.
1998: Toshimi Michigami; M Nomizu; Y Yamada; C Dunstan; Paul J Williams; G R Munday; Toshiyuki Yoneda
Growth and dissemination of a newly-established murine B-cell lymphoma cell line is inhibited by multimeric YIGSR peptide.
Clinical & experimental metastasis 1998;16(7):645-54.
1997: Toshiyuki Yoneda; Akira Sasaki; C Dunstan; Paul J Williams; F Bauss; Y A De Clerck; Gregory R Mundy
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
The Journal of clinical investigation 1997;99(10):2509-17.
1996: G Mbalaviele; C R Dunstan; Akira Sasaki; Paul J Williams; Gregory R Mundy; Toshiyuki Yoneda
E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model.
Cancer research 1996;56(17):4063-70.
1996: K Moriyama; Paul J Williams; M Niewolna; Mark Dallas; Y Uehara; Gregory R Mundy; Toshiyuki Yoneda
Herbimycin A, a tyrosine kinase inhibitor, impairs hypercalcemia associated with a human squamous cancer producing interleukin-6 in nude mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(7):905-11.
1993: Toshiyuki Yoneda; C Lowe; C H Lee; G Gutierrez; M Niewolna; Paul J Williams; Elzbieta Izbicka; Y Uehara; Gregory R Mundy
Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo.
The Journal of clinical investigation 1993;91(6):2791-5.
1992: M Nakai; Gregory R Mundy; Paul J Williams; B Boyce; Toshiyuki Yoneda
A synthetic antagonist to laminin inhibits the formation of osteolytic metastases by human melanoma cells in nude mice.
Cancer research 1992;52(19):5395-9.