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Robert Williams

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TOP 3
Alan B Watts; Keith P Johnston; Yi-Bo Wang; Robert O Williams
Respirable low-density microparticles formed in situ from aerosolized brittle matrices.
Kevin P O'Donnell; Robert O Williams
Pulmonary dispersion formulations: the impact of dispersed powder properties on pressurized metered dose inhaler stability.
K P O'Donnell; P Schmerler; Z Cai; Robert O Williams
Atmospheric freeze drying for the reduction of powder electrostatics of amorphous, low density, high surface area pharmaceutical powders.

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All Publications

2013: Alan B Watts; Keith P Johnston; Yi-Bo Wang; Robert O Williams
Respirable low-density microparticles formed in situ from aerosolized brittle matrices.
Pharmaceutical research 2013;30(3):813-25.
2013: Kevin P O'Donnell; Robert O Williams
Pulmonary dispersion formulations: the impact of dispersed powder properties on pressurized metered dose inhaler stability.
Drug development and industrial pharmacy 2013;39(3):413-24.
2013: K P O'Donnell; P Schmerler; Z Cai; Robert O Williams
Atmospheric freeze drying for the reduction of powder electrostatics of amorphous, low density, high surface area pharmaceutical powders.
Drug development and industrial pharmacy 2013;39(2):205-17.
2013: Hélène L Dugas; Jay Peters; Robert O Williams
Nebulization of mycophenolate mofetil inhalation suspension in rats: comparison with oral and pulmonary administration of Cellcept®.
International journal of pharmaceutics 2013;441(1-2):19-29.
2012: Meimei Zhang; Chuanbin Wu; Haohao Zhang; Yixuan Dong; Bo Lang; Houli Li; Kevin O'Donnell; Zhouhua Wang; Robert O Williams
Formulation and delivery of improved amorphous fenofibrate solid dispersions prepared by thin film freezing.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;82(3):534-44.
2012: Stephanie Bosselmann; Keat T Chow; Masao Nagao; Robert O Williams
Influence of formulation and processing variables on properties of itraconazole nanoparticles made by advanced evaporative precipitation into aqueous solution.
AAPS PharmSciTech 2012;13(3):949-60.
2012: Nicole A Beinborn; Ju Du; Hugh D C Smyth; Nathan Wiederhold; Robert O Williams
Dry powder insufflation of crystalline and amorphous voriconazole formulations produced by thin film freezing to mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012;81(3):600-8.
2012: Nicole A Beinborn; Hélène L Lirola; Robert O Williams
Effect of process variables on morphology and aerodynamic properties of voriconazole formulations produced by thin film freezing.
International journal of pharmaceutics 2012;429(1-2):46-57.
2012: Maria A Miller; Robert O Williams; James DiNunzio; Baltej S Ludher; Michal E Matteucci; Keith P Johnston
Flocculated amorphous itraconazole nanoparticles for enhanced in vitro supersaturation and in vivo bioavailability.
Drug development and industrial pharmacy 2012;38(5):557-70.
2011: Javier O Morales; Jay Peters; Robert O Williams
Surfactants: their critical role in enhancing drug delivery to the lungs.
Therapeutic delivery 2011;2(5):623-41.
2011: Stephanie Bosselmann; Donald E Owens; Rachel L Kennedy; Matthew J Herpin; Robert O Williams
Plasma deposited stability enhancement coating for amorphous ketoprofen.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011;78(1):67-74.
2011: Thiago C Carvalho; Jay Peters; Robert O Williams
Influence of particle size on regional lung deposition--what evidence is there?
International journal of pharmaceutics 2011;406(1-2):1-10.
2011: Alan B Watts; Jay Peters; Robert L Talbert; Kevin P O'Donnell; Jacqueline J Coalson; Robert O Williams
Preclinical evaluation of tacrolimus colloidal dispersion for inhalation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011;77(2):207-15.
2010: Jasmine M Tam; Josh D Engstrom; Domingo Ferrer; Robert O Williams; Keith P Johnston
Templated open flocs of anisotropic particles for pulmonary delivery with pressurized metered dose inhalers.
Journal of pharmaceutical sciences 2010;99(7):3150-65.
2010: James C DiNunzio; Chris Brough; Dave A Miller; Robert O Williams; James W McGinity
Applications of KinetiSol dispersing for the production of plasticizer free amorphous solid dispersions.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;40(3):179-87.
2010: Justin R Hughey; James C DiNunzio; Ryan C Bennett; Chris Brough; Dave A Miller; Hua Ma; Robert O Williams; James W McGinity
Dissolution enhancement of a drug exhibiting thermal and acidic decomposition characteristics by fusion processing: a comparative study of hot melt extrusion and KinetiSol dispersing.
AAPS PharmSciTech 2010;11(2):760-74.
2010: Wei Yang; Keith P Johnston; Robert O Williams
Comparison of bioavailability of amorphous versus crystalline itraconazole nanoparticles via pulmonary administration in rats.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010;75(1):33-41.
2010: Wei Yang; Keat Theng Chow; Bo Lang; Nathan Wiederhold; Keith P Johnston; Robert O Williams
In vitro characterization and pharmacokinetics in mice following pulmonary delivery of itraconazole as cyclodextrin solubilized solution.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;39(5):336-47.
2010: James C DiNunzio; Chris Brough; Dave A Miller; Robert O Williams; James W McGinity
Fusion processing of itraconazole solid dispersions by kinetisol dispersing: a comparative study to hot melt extrusion.
Journal of pharmaceutical sciences 2010;99(3):1239-53.
2010: James C Dinunzio; Chris Brough; Justin R Hughey; Dave A Miller; Robert O Williams; James W McGinity
Fusion production of solid dispersions containing a heat-sensitive active ingredient by hot melt extrusion and Kinetisol dispersing.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010;74(2):340-51.
2010: Alan B Watts; Adam M Cline; Adham R Saad; Scott B Johnson; Jay Peters; Robert O Williams
Characterization and pharmacokinetic analysis of tacrolimus dispersion for nebulization in a lung transplanted rodent model.
International journal of pharmaceutics 2010;384(1-2):46-52.
2009: Justin A Tolman; Nicole A Nelson; Stephanie Bosselmann; Jay Peters; Jacqueline J Coalson; Nathan Wiederhold; Robert O Williams
Dose tolerability of chronically inhaled voriconazole solution in rodents.
International journal of pharmaceutics 2009;379(1):25-31.
2009: Justin A Tolman; Nicole A Nelson; Yoen Ju Son; Stephanie Bosselmann; Nathan Wiederhold; Jay Peters; Jason T McConville; Robert O Williams
Characterization and pharmacokinetic analysis of aerosolized aqueous voriconazole solution.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;72(1):199-205.
2009: Xiaoxia Chen; Michal E Matteucci; Connie Y Lo; Keith P Johnston; Robert O Williams
Flocculation of polymer stabilized nanocrystal suspensions to produce redispersible powders.
Drug development and industrial pharmacy 2009;35(3):283-96.
2009: Alan B Watts; Robert O Williams; Jay Peters
Recent developments in drug delivery to prolong allograft survival in lung transplant patients.
Drug development and industrial pharmacy 2009;35(3):259-71.
2008: Michal E Matteucci; Maria A Miller; Robert O Williams; Keith P Johnston
Highly supersaturated solutions of amorphous drugs approaching predictions from configurational thermodynamic properties.
The journal of physical chemistry. B 2008;112(51):16675-81.
2008: James C DiNunzio; Dave A Miller; Wei Yang; James W McGinity; Robert O Williams
Amorphous compositions using concentration enhancing polymers for improved bioavailability of itraconazole.
Molecular pharmaceutics 2008;5(6):968-80.
2008: Wei Yang; Nathan Wiederhold; Robert O Williams
Drug delivery strategies for improved azole antifungal action.
Expert opinion on drug delivery 2008;5(11):1199-216.
2008: James C DiNunzio; Robert O Williams
CNS disorders--current treatment options and the prospects for advanced therapies.
Drug development and industrial pharmacy 2008;34(11):1141-67.
2008: Jasmine M Tam; Jason T McConville; Robert O Williams; Keith P Johnston
Amorphous cyclosporin nanodispersions for enhanced pulmonary deposition and dissolution.
Journal of pharmaceutical sciences 2008;97(11):4915-33.
2008: Alan B Watts; Jason T McConville; Robert O Williams
Current therapies and technological advances in aqueous aerosol drug delivery.
Drug development and industrial pharmacy 2008;34(9):913-22.
2008: Wei Yang; Jasmine Tam; Dave A Miller; Jiping Zhou; Jason T McConville; Keith P Johnston; Robert O Williams
High bioavailability from nebulized itraconazole nanoparticle dispersions with biocompatible stabilizers.
International journal of pharmaceutics 2008;361(1-2):177-88.
2008: Dave A Miller; James C DiNunzio; Wei Yang; James W McGinity; Robert O Williams
Enhanced in vivo absorption of itraconazole via stabilization of supersaturation following acidic-to-neutral pH transition.
Drug development and industrial pharmacy 2008;34(8):890-902.
2008: Prapasri Sinswat; Kirk A Overhoff; Jason T McConville; Keith P Johnston; Robert O Williams
Nebulization of nanoparticulate amorphous or crystalline tacrolimus--single-dose pharmacokinetics study in mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(3):1057-66.
2008: Dave A Miller; James C DiNunzio; Wei Yang; James W McGinity; Robert O Williams
Targeted intestinal delivery of supersaturated itraconazole for improved oral absorption.
Pharmaceutical research 2008;25(6):1450-9.
2008: Josh D Engstrom; Edwina S Lai; Baltej S Ludher; Bo Chen; Thomas E Milner; Robert O Williams; G Barrie Kitto; Keith P Johnston
Formation of stable submicron protein particles by thin film freezing.
Pharmaceutical research 2008;25(6):1334-46.
2008: Wei Yang; Jay Peters; Robert O Williams
Inhaled nanoparticles--a current review.
International journal of pharmaceutics 2008;356(1-2):239-47.
2008: Dave A Miller; James C Dinunzio; Robert O Williams
Advanced formulation design: improving drug therapies for the management of severe and chronic pain.
Drug development and industrial pharmacy 2008;34(2):117-33.
2008: Kirk A Overhoff; Jason T McConville; Wei Yang; Keith P Johnston; Jay Peters; Robert O Williams
Effect of stabilizer on the maximum degree and extent of supersaturation and oral absorption of tacrolimus made by ultra-rapid freezing.
Pharmaceutical research 2008;25(1):167-75.
2007: Michal E Matteucci; Blair K Brettmann; True L Rogers; Edmund J Elder; Robert O Williams; Keith P Johnston
Design of potent amorphous drug nanoparticles for rapid generation of highly supersaturated media.
Molecular pharmaceutics 2007;4(5):782-93.
2007: Carlos A Alvarez; Nathan Wiederhold; Jason T McConville; Jay Peters; Laura K Najvar; John Graybill; Jacqueline J Coalson; Robert L Talbert; David S Burgess; Rosie Bocanegra; Keith P Johnston; Robert O Williams
Aerosolized nanostructured itraconazole as prophylaxis against invasive pulmonary aspergillosis.
The Journal of infection 2007;55(1):68-74.
2007: Jason M Vaughn; Nathan Wiederhold; Jason T McConville; Jacqueline J Coalson; Robert L Talbert; David S Burgess; Keith P Johnston; Robert O Williams; Jay Peters
Murine airway histology and intracellular uptake of inhaled amorphous itraconazole.
International journal of pharmaceutics 2007;338(1-2):219-24.
2007: Kirk A Overhoff; Alejandro Moreno; Dave A Miller; Keith P Johnston; Robert O Williams
Solid dispersions of itraconazole and enteric polymers made by ultra-rapid freezing.
International journal of pharmaceutics 2007;336(1):122-32.
2007: Matthew Todd Crisp; Christopher J Tucker; True L Rogers; Robert O Williams; Keith P Johnston
Turbidimetric measurement and prediction of dissolution rates of poorly soluble drug nanocrystals.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(3):351-9.
2007: Dave A Miller; Mirko Gamba; Dorothea Sauer; Troy Purvis; Noel T Clemens; Robert O Williams
Evaluation of the USP dissolution test method A for enteric-coated articles by planar laser-induced fluorescence.
International journal of pharmaceutics 2007;330(1-2):61-72.
2007: Dave A Miller; Jason T McConville; Wei Yang; Robert O Williams; James W McGinity
Hot-melt extrusion for enhanced delivery of drug particles.
Journal of pharmaceutical sciences 2007;96(2):361-76.
2007: Josh D Engstrom; Dale T Simpson; Carrie Cloonan; Edwina S Lai; Robert O Williams; G Barrie Kitto; Keith P Johnston
Stable high surface area lactate dehydrogenase particles produced by spray freezing into liquid nitrogen.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;65(2):163-74.
2007: Josh D Engstrom; Dale T Simpson; Edwina S Lai; Robert O Williams; Keith P Johnston
Morphology of protein particles produced by spray freezing of concentrated solutions.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;65(2):149-62.
2007: Troy Purvis; Michal E Mattucci; Matthew Todd Crisp; Keith P Johnston; Robert O Williams
Rapidly dissolving repaglinide powders produced by the ultra-rapid freezing process.
AAPS PharmSciTech 2007;8(3):E58.
2007: Kirk A Overhoff; Josh D Engstrom; Bo Chen; Brian D Scherzer; Thomas E Milner; Keith P Johnston; Robert O Williams
Novel ultra-rapid freezing particle engineering process for enhancement of dissolution rates of poorly water-soluble drugs.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;65(1):57-67.
2006: Troy Purvis; Jason M Vaughn; True L Rogers; Xiaoxia Chen; Kirk A Overhoff; Prapasri Sinswat; Jiahui Hu; Jason T McConville; Keith P Johnston; Robert O Williams
Cryogenic liquids, nanoparticles, and microencapsulation.
International journal of pharmaceutics 2006;324(1):43-50.
2006: Michal E Matteucci; Margaret A Hotze; Keith P Johnston; Robert O Williams
Drug nanoparticles by antisolvent precipitation: mixing energy versus surfactant stabilization.
Langmuir : the ACS journal of surfaces and colloids 2006;22(21):8951-9.
2006: Jason M Vaughn; Jason T McConville; Matthew Todd Crisp; Keith P Johnston; Robert O Williams
Supersaturation produces high bioavailability of amorphous danazol particles formed by evaporative precipitation into aqueous solution and spray freezing into liquid technologies.
Drug development and industrial pharmacy 2006;32(5):559-67.
2006: Jason M Vaughn; Jason T McConville; David Burgess; Jay Peters; Keith P Johnston; Robert L Talbert; Robert O Williams
Single dose and multiple dose studies of itraconazole nanoparticles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2006;63(2):95-102.
2006: Jason T McConville; Kirk A Overhoff; Prapasri Sinswat; Jason M Vaughn; Bradi L Frei; David S Burgess; Robert L Talbert; Jay Peters; Keith P Johnston; Robert O Williams
Targeted high lung concentrations of itraconazole using nebulized dispersions in a murine model.
Pharmaceutical research 2006;23(5):901-11.
2006: Barbara J Hoeben; David S Burgess; Jason T McConville; Laura K Najvar; Robert L Talbert; Jay Peters; Nathan Wiederhold; Bradi L Frei; John Graybill; Rosie Bocanegra; Kirk A Overhoff; Prapasri Sinswat; Keith P Johnston; Robert O Williams
In vivo efficacy of aerosolized nanostructured itraconazole formulations for prevention of invasive pulmonary aspergillosis.
Antimicrobial agents and chemotherapy 2006;50(4):1552-4.
2006: Zhongshui Yu; Keith P Johnston; Robert O Williams
Spray freezing into liquid versus spray-freeze drying: influence of atomization on protein aggregation and biological activity.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;27(1):9-18.
2005: Prapasri Sinswat; Xiaoxia Gao; Miguel J Yacaman; Robert O Williams; Keith P Johnston
Stabilizer choice for rapid dissolving high potency itraconazole particles formed by evaporative precipitation into aqueous solution.
International journal of pharmaceutics 2005;302(1-2):113-24.
2005: Jason M Vaughn; Xiaoxia Gao; Miguel J Yacaman; Keith P Johnston; Robert O Williams
Comparison of powder produced by evaporative precipitation into aqueous solution (EPAS) and spray freezing into liquid (SFL) technologies using novel Z-contrast STEM and complimentary techniques.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;60(1):81-9.
2005: W Thomas Leach; Dale T Simpson; Tibisay N Val; Zhongshui Yu; Kwon T Lim; Eun J Park; Robert O Williams; Keith P Johnston
Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film.
AAPS PharmSciTech 2005;6(4):E605-17.
2005: W Thomas Leach; Dale T Simpson; Tibisay N Val; Efemona C Anuta; Zhongshui Yu; Robert O Williams; Keith P Johnston
Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release.
Journal of pharmaceutical sciences 2005;94(1):56-69.
2005: Jason T McConville; Robert O Williams; Thiago C Carvalho; Aimee N Iberg; Keith P Johnston; Robert L Talbert; David Burgess; Jay Peters
Design and evaluation of a restraint-free small animal inhalation dosing chamber.
Drug development and industrial pharmacy 2005;31(1):35-42.
2004: Zhongshui Yu; Ana S Garcia; Keith P Johnston; Robert O Williams
Spray freezing into liquid nitrogen for highly stable protein nanostructured microparticles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(3):529-37.
2004: Xiaoxia Chen; Jason M Vaughn; Miguel J Yacaman; Robert O Williams; Keith P Johnston
Rapid dissolution of high-potency danazol particles produced by evaporative precipitation into aqueous solution.
Journal of pharmaceutical sciences 2004;93(7):1867-78.
2004: Jiahui Hu; Keith P Johnston; Robert O Williams
Rapid dissolving high potency danazol powders produced by spray freezing into liquid process.
International journal of pharmaceutics 2004;271(1-2):145-54.
2003: Vorapann Mahaguna; Robert L Talbert; Jay Peters; Sandra Adams; Thomas D Reynolds; Yui-Wing Lam; Robert O Williams
Influence of hydroxypropyl methylcellulose polymer on in vitro and in vivo performance of controlled release tablets containing alprazolam.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2003;56(3):461-8.
2003: Jiahui Hu; Keith P Johnston; Robert O Williams
Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;20(3):295-303.
2003: True L Rogers; Andrew C Nelsen; Marazban Sarkari; Timothy J Young; Keith P Johnston; Robert O Williams
Enhanced aqueous dissolution of a poorly water soluble drug by novel particle engineering technology: spray-freezing into liquid with atmospheric freeze-drying.
Pharmaceutical research 2003;20(3):485-93.
2003: True L Rogers; Kirk A Overhoff; Parag Shah; Patricia Santiago; Miguel J Yacaman; Keith P Johnston; Robert O Williams
Micronized powders of a poorly water soluble drug produced by a spray-freezing into liquid-emulsion process.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2003;55(2):161-72.
2003: Melisa K Barron; Timothy J Young; Keith P Johnston; Robert O Williams
Investigation of processing parameters of spray freezing into liquid to prepare polyethylene glycol polymeric particles for drug delivery.
AAPS PharmSciTech 2003;4(2):E12.
2003: True L Rogers; Keith P Johnston; Robert O Williams
Physical stability of micronized powders produced by spray-freezing into liquid (SFL) to enhance the dissolution of an insoluble drug.
Pharmaceutical development and technology 2003;8(2):187-97.
2002: True L Rogers; Andrew C Nelsen; Jiahui Hu; Judith N Brown; Marazban Sarkari; Timothy J Young; Keith P Johnston; Robert O Williams
A novel particle engineering technology to enhance dissolution of poorly water soluble drugs: spray-freezing into liquid.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;54(3):271-80.
2002: Jiping Liu; Robert O Williams
Properties of heat-humidity cured cellulose acetate phthalate free films.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;17(1-2):31-41.
2002: Jiahui Hu; True L Rogers; Judith Brown; Tim Young; Keith P Johnston; Robert O Williams
Improvement of dissolution rates of poorly water soluble APIs using novel spray freezing into liquid technology.
Pharmaceutical research 2002;19(9):1278-84.
2002: Zhongshui Yu; True L Rogers; Jiahui Hu; Keith P Johnston; Robert O Williams
Preparation and characterization of microparticles containing peptide produced by a novel process: spray freezing into liquid.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;54(2):221-8.
2002: Marazban Sarkari; Judith Brown; Xiaoxia Chen; Steve Swinnea; Robert O Williams; Keith P Johnston
Enhanced drug dissolution using evaporative precipitation into aqueous solution.
International journal of pharmaceutics 2002;243(1-2):17-31.
2002: True L Rogers; Jiahui Hu; Zhongshui Yu; Keith P Johnston; Robert O Williams
A novel particle engineering technology: spray-freezing into liquid.
International journal of pharmaceutics 2002;242(1-2):93-100.
2002: Xiaoxia Chen; Timothy J Young; Marazban Sarkari; Robert O Williams; Keith P Johnston
Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution.
International journal of pharmaceutics 2002;242(1-2):3-14.
2002: Robert O Williams; Thomas D Reynolds; Tim D Cabelka; Matthew A Sykora; Vorapann Mahaguna
Investigation of excipient type and level on drug release from controlled release tablets containing HPMC.
Pharmaceutical development and technology 2002;7(2):181-93.
2001: True L Rogers; Keith P Johnston; Robert O Williams
Solution-based particle formation of pharmaceutical powders by supercritical or compressed fluid CO2 and cryogenic spray-freezing technologies.
Drug development and industrial pharmacy 2001;27(10):1003-15.
2001: Robert O Williams; Jiping Liu
The influence of plasticizer on heat-humidity curing of cellulose acetate phthalate coated beads.
Pharmaceutical development and technology 2001;6(4):607-19.
2001: Robert O Williams; A M Patel; MK Barron; True L Rogers
Investigation of some commercially available spacer devices for the delivery of glucocorticoid steroids from a pMDI.
Drug development and industrial pharmacy 2001;27(5):401-12.
2001: Robert O Williams; M A Sykora; Vorapann Mahaguna
Method to recover a lipophilic drug from hydroxypropyl methylcellulose matrix tablets.
AAPS PharmSciTech 2001;2(2):E8.
2001: Robert O Williams; C Hu
Influence of water on the solubility of two steroid drugs in hydrofluoroalkane (HFA) propellants.
Drug development and industrial pharmacy 2001;27(1):71-9.
2000: Robert O Williams; Jiping Liu
Influence of processing and curing conditions on beads coated with an aqueous dispersion of cellulose acetate phthalate.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;49(3):243-52.
2000: Vorapann Mahaguna; Robert O Williams; Thomas C Hardin
Trends in antifungal research.
EXS 2000;89():55-68.
2000: Robert O Williams; C Hu
Moisture uptake and its influence on pressurized metered-dose inhalers.
Pharmaceutical development and technology 2000;5(2):153-62.
1999: Robert O Williams; True L Rogers; Jiping Liu
Study of solubility of steroids in hydrofluoroalkane propellants.
Drug development and industrial pharmacy 1999;25(12):1227-34.
1999: Robert O Williams; Michael A Repka; MK Barron
Application of co-grinding to formulate a model pMDI suspension.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1999;48(2):131-40.
1999: Robert O Williams; Judith Brown; Jiping Liu
Influence of micronization method on the performance of a suspension triamcinolone acetonide pressurized metered-dose inhaler formulation.
Pharmaceutical development and technology 1999;4(2):167-79.
1999: Robert O Williams; Jiping Liu
Influence of formulation technique for hydroxypropyl-beta-cyclodextrin on the stability of aspirin in HFA 134a.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1999;47(2):145-52.
1999: Robert O Williams; Jiping Liu
Formulation of a protein with propellant HFA 134a for aerosol delivery.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;7(2):137-44.
1998: Robert O Williams; Vorapann Mahaguna; M Sriwongjanya
Characterization of an inclusion complex of cholesterol and hydroxypropyl-beta-cyclodextrin.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1998;46(3):355-60.
1998: Robert O Williams; MK Barron
Influence of temperature on the emitted dose of an oral metered dose inhaler.
Drug development and industrial pharmacy 1998;24(11):1043-8.
1998: Robert O Williams; Michael A Repka; Jiping Liu
Influence of propellant composition on drug delivery from a pressurized metered-dose inhaler.
Drug development and industrial pharmacy 1998;24(8):763-70.
1998: Robert O Williams; Vorapann Mahaguna
Preformulation studies on Freund's incomplete adjuvant emulsion.
Drug development and industrial pharmacy 1998;24(2):157-62.
1997: Robert O Williams; Vorapann Mahaguna; M Sriwongjanya
Determination of diazolidinyl urea in a topical cream by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1997;696(2):303-6.
1997: Robert O Williams; Jiping Liu; John J Koleng
Influence of metering chamber volume and water level on the emitted dose of a suspension-based pMDI containing propellant 134a.
Pharmaceutical research 1997;14(4):438-43.
1997: Robert O Williams; M Sriwongjanya; Jiping Liu
An in vitro method to investigate food effects on drug release from film-coated beads.
Pharmaceutical development and technology 1997;2(1):1-9.