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Wanda Williams

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Lak Shin Jeong; Hyuk Woo Lee; Hea Ok Kim; Dilip K Tosh; Shantanu Pal; Won Jun Choi; Zhan-Guo Gao; Amit R Patel; Wanda Williams; Kenneth Alan Jacobson; Hee-Doo Kim
Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists.
Rae Reiko Matsumoto; Deborah L Gilmore; Buddy Pouw; Wayne D Bowen; Wanda Williams; Amina Kausar; Andrew Coop
Novel analogs of the sigma receptor ligand BD1008 attenuate cocaine-induced toxicity in mice.
Jianjing Cao; Santosh S Kulkarni; Stephen M Husbands; Wayne D Bowen; Wanda Williams; Theresa A Kopajtic; Jonathan L Katz; Clifford George; Amy Hauck Newman
Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.

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2008: Lak Shin Jeong; Hyuk Woo Lee; Hea Ok Kim; Dilip K Tosh; Shantanu Pal; Won Jun Choi; Zhan-Guo Gao; Amit R Patel; Wanda Williams; Kenneth Alan Jacobson; Hee-Doo Kim
Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists.
Bioorganic & medicinal chemistry letters 2008;18(5):1612-6.
2004: Rae Reiko Matsumoto; Deborah L Gilmore; Buddy Pouw; Wayne D Bowen; Wanda Williams; Amina Kausar; Andrew Coop
Novel analogs of the sigma receptor ligand BD1008 attenuate cocaine-induced toxicity in mice.
European journal of pharmacology 2004;492(1):21-6.
2003: Jianjing Cao; Santosh S Kulkarni; Stephen M Husbands; Wayne D Bowen; Wanda Williams; Theresa A Kopajtic; Jonathan L Katz; Clifford George; Amy Hauck Newman
Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
Journal of medicinal chemistry 2003;46(13):2589-98.
2003: Abby Foster; Huifang Wu; Weibin Chen; Wanda Williams; Wayne D Bowen; Rae Reiko Matsumoto; Andrew Coop
1,4-dibenzylpiperazines possess anticocaine activity.
Bioorganic & medicinal chemistry letters 2003;13(4):749-51.
2002: Dean Y Maeda; Wanda Williams; Wes E Kim; Linn N Thatcher; Wayne D Bowen; Andrew Coop
N-arylalkylpiperidines as high-affinity sigma-1 and sigma-2 receptor ligands: phenylpropylamines as potential leads for selective sigma-2 agents.
Bioorganic & medicinal chemistry letters 2002;12(3):497-500.
2001: Rae Reiko Matsumoto; Kari A McCracken; Buddy Pouw; J Miller; Wayne D Bowen; Wanda Williams; BR De Costa
N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in mice.
European journal of pharmacology 2001;411(3):261-73.
2000: Dean Y Maeda; Wanda Williams; Wayne D Bowen; Andrew Coop
A sigma-1 receptor selective analogue of BD1008. A potential substitute for (+)-opioids in sigma receptor binding assays.
Bioorganic & medicinal chemistry letters 2000;10(1):17-8.
1999: Frank carroll; X Bai; A Dehghani; Wayne Mascarella; Wanda Williams; W D Bowen
Asymmetric synthesis of 9-alkyl-2-benzyl-6,7-benzomorphans: characterization as novel sigma receptor ligands.
Journal of medicinal chemistry 1999;42(22):4621-9.
1998: Ying Zhang; Wanda Williams; C Torrence-Campbell; Wayne D Bowen; Kenner C Rice
Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands.
Journal of medicinal chemistry 1998;41(25):4950-7.
1996: Ying Zhang; Wanda Williams; Wayne D Bowen; Kenner C Rice
Synthesis and evaluation of aryl-substituted N-(arylethyl)-N-methyl-2-(1-pyrrolidinyl)ethylamines and corresponding arylacetamides for sigma receptor affinity.
Journal of medicinal chemistry 1996;39(18):3564-8.
1995: R Danso-Danquah; X Bai; X Zhang; Wayne Mascarella; Wanda Williams; B Sine; Wayne D Bowen; Frank carroll
Synthesis and sigma binding properties of 1'- and 3'-halo- and 1',3'-dihalo-N-normetazocine analogues.
Journal of medicinal chemistry 1995;38(15):2986-9.
1995: R Danso-Danquah; X Bai; X Zhang; Wayne Mascarella; Wanda Williams; B Sine; Wayne D Bowen; Frank carroll
Synthesis and sigma binding properties of 2'-substituted 5,9 alpha-dimethyl-6,7-benzomorphans.
Journal of medicinal chemistry 1995;38(15):2978-85.
1995: Wayne D Bowen; BJ Vilner; Wanda Williams; C M Bertha; Martin E Kuehne; Arthur E Jacobson
Ibogaine and its congeners are sigma 2 receptor-selective ligands with moderate affinity.
European journal of pharmacology 1995;279(1):R1-3.
1995: Wayne Mascarella; X Bai; Wanda Williams; B Sine; Wayne D Bowen; Frank carroll
(+)-cis-N-(para-, meta-, and ortho-substituted benzyl)-N-normetazocines: synthesis and binding affinity at the [3H]-(+)-pentazocine-labeled (sigma 1) site and quantitative structure-affinity relationship studies.
Journal of medicinal chemistry 1995;38(3):565-9.
1994: S B Hellewell; A Bruce; G Feinstein; J Orringer; Wanda Williams; Wayne D Bowen
Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.
European journal of pharmacology 1994;268(1):9-18.
1994: B R de Costa; X S He; C Dominguez; J Cutts; Wanda Williams; Wayne D Bowen
A new approach to the design of sigma-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes.
Journal of medicinal chemistry 1994;37(2):314-21.
1993: B R de Costa; X S He; J T Linders; C Dominguez; Z Q Gu; Wanda Williams; Wayne D Bowen
Synthesis and evaluation of conformationally restricted N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamines at sigma receptors. 2. Piperazines, bicyclic amines, bridged bicyclic amines, and miscellaneous compounds.
Journal of medicinal chemistry 1993;36(16):2311-20.
1993: X S He; Wayne D Bowen; K S Lee; Wanda Williams; Daniel R Weinberger; B R de Costa
Synthesis and binding characteristics of potential SPECT imaging agents for sigma-1 and sigma-2 binding sites.
Journal of medicinal chemistry 1993;36(5):566-71.
1993: J Michael Walker; Wayne D Bowen; S L Patrick; Wanda Williams; Wayne Mascarella; X Bai; Frank carroll
A comparison of (-)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of sigma 2 receptors in motor function.
European journal of pharmacology 1993;231(1):61-8.
1992: B R de Costa; C Dominguez; X S He; Wanda Williams; L Radesca; W Bowen
Synthesis and biological evaluation of conformationally restricted 2-(1-pyrrolidinyl)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methylethylenediam ines as sigma receptor ligands. 1. Pyrrolidine, piperidine, homopiperidine, and tetrahydroisoquinoline classes.
Journal of medicinal chemistry 1992;35(23):4334-43.
1990: Wanda Williams; Kenner C Rice; Richard J. Weber
Nonpeptide opioids: in vivo effects on the immune system.
NIDA research monograph 1990;105():404-7.