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Alex Wilson

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TOP 3
Jo C Martindale; Alex W Wilson; Alison J Reeve; Iain P Chessell; P M Headley
Chronic secondary hypersensitivity of dorsal horn neurones following inflammation of the knee joint.
Nicola J Barton; Iain T Strickland; Susan M Bond; Harry M Brash; Simon T Bate; Alex W Wilson; Iain P Chessell; Alison J Reeve; Daniel S McQueen
Pressure application measurement (PAM): a novel behavioural technique for measuring hypersensitivity in a rat model of joint pain.
Gerard M P Giblin; Celestine T O'Shaughnessy; Alan Naylor; William L Mitchell; Andrew J Eatherton; Brian P Slingsby; D Anthony Rawlings; Paul Goldsmith; Andrew J Brown; Claudine Haslam; Nicholas M Clayton; Alex W Wilson; Iain P Chessell; Andrew R Wittington; Richard Green
Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.

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All Publications

2007: Jo C Martindale; Alex W Wilson; Alison J Reeve; Iain P Chessell; P M Headley
Chronic secondary hypersensitivity of dorsal horn neurones following inflammation of the knee joint.
Pain 2007;133(1-3):79-86.
2007: Nicola J Barton; Iain T Strickland; Susan M Bond; Harry M Brash; Simon T Bate; Alex W Wilson; Iain P Chessell; Alison J Reeve; Daniel S McQueen
Pressure application measurement (PAM): a novel behavioural technique for measuring hypersensitivity in a rat model of joint pain.
Journal of neuroscience methods 2007;163(1):67-75.
2007: Gerard M P Giblin; Celestine T O'Shaughnessy; Alan Naylor; William L Mitchell; Andrew J Eatherton; Brian P Slingsby; D Anthony Rawlings; Paul Goldsmith; Andrew J Brown; Claudine Haslam; Nicholas M Clayton; Alex W Wilson; Iain P Chessell; Andrew R Wittington; Richard Green
Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.
Journal of medicinal chemistry 2007;50(11):2597-600.
2007: Penny C Staton; Alex W Wilson; Chas Bountra; Iain P Chessell; Nicola C Day
Changes in dorsal root ganglion CGRP expression in a chronic inflammatory model of the rat knee joint: differential modulation by rofecoxib and paracetamol.
European journal of pain (London, England) 2007;11(3):283-9.
2007: Gerard M P Giblin; Rino A Bit; Susan H Brown; Helene Chaignot; Anita Chowdhury; Iain P Chessell; Nicholas M Clayton; Tanya Coleman; Adrian Hall; Beverley Hammond; David N Hurst; Anton D Michel; Alan Naylor; Riccardo Novelli; Tiziana Scoccitti; David J Spalding; Sac P Tang; Alex W Wilson; Rich Wilson
The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.
Bioorganic & medicinal chemistry letters 2007;17(2):385-9.
2006: Nicola J Barton; Daniel S McQueen; D Thomson; Stephan D Gauldie; Alex W Wilson; D M Salter; Iain P Chessell
Attenuation of experimental arthritis in TRPV1R knockout mice.
Experimental and molecular pathology 2006;81(2):166-70.
2006: Alex W Wilson; Stephen J Medhurst; Claire I Dixon; Nick C Bontoft; Lisa A Winyard; Kim T Brackenborough; Jorge De Alba; Christopher J Clarke; Martin Gunthorpe; Gareth Hicks; Chas Bountra; Daniel S McQueen; Iain P Chessell
An animal model of chronic inflammatory pain: pharmacological and temporal differentiation from acute models.
European journal of pain (London, England) 2006;10(6):537-49.
2006: Pascal F Durrenberger; Paul Facer; Maria A Casula; Yiangos Yiangou; Roy A Gray; Iain P Chessell; Nicola C Day; Sue D Collins; Sharon Bingham; Alex W Wilson; David Elliot; Rolfe Birch; Praveen Anand
Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study.
BMC neurology 2006;6():1.
2005: Steven J R Elmes; Lisa A Winyard; Stephen J Medhurst; Nicholas M Clayton; Alex W Wilson; David A Kendall; Victoria Chapman
Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat.
Pain 2005;118(3):327-35.