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Ian Wilson
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35
Stura, EA
28
Burton, Dennis
27
Teyton, Luc
22
Stanfield, Robyn
17
Dwek, Raymond
16
Benkovic, Stephen
15
Rudd, Pauline
15
Lerner, Richard
15
Zajonc, Dirk
14
Garcia, Christopher
14
Heine, Andreas
13
Boger, Dale
13
Peterson, PA
13
Wong, Chi-Huey
11
Zwick, Michael
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All Publications
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2009: Debler Erik W; Müller Roger; Hilvert Donald; Wilson Ian A
An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(44):18539-44.
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2009: Schiefner André; Fujio Masakazu; Wu Douglass; Wong Chi-Huey; Wilson Ian A
Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
Journal of molecular biology 2009;394(1):71-82.
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2009: Pejchal Robert; Gach Johannes S; Brunel Florence M; Cardoso Rosa M; Stanfield Robyn L; Dawson Philip E; Burton Dennis R; Zwick Michael B; Wilson Ian A
A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies.
Journal of virology 2009;83(17):8451-62.
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2009: An Yu; Chen Christine Y; Moyer Bryan; Rotkiewicz Piotr; Elsliger Marc-André; Godzik Adam; Wilson Ian A; Balch William E
Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering.
Journal of molecular biology 2009;391(1):26-41.
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2009: Ekiert Damian C; Bhabha Gira; Elsliger Marc-André; Friesen Robert H E; Jongeneelen Mandy; Throsby Mark; Goudsmit Jaap; Wilson Ian A
Antibody recognition of a highly conserved influenza virus epitope.
Science (New York, N.Y.) 2009;324(5924):246-51.
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2009: Johnson Steven M; Connelly Stephen; Wilson Ian A; Kelly Jeffery W
Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
Journal of medicinal chemistry 2009;52(4):1115-25.
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2009: Wang Wei; Fridman Alla; Blackledge William; Connelly Stephen; Wilson Ian A; Pilz Renate B; Boss Gerry R
The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis.
The Journal of biological chemistry 2009;284(6):3521-8.
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2009: Schiefner André; Wilson Ian A
Presentation of lipid antigens by CD1 glycoproteins.
Current pharmaceutical design 2009;15(28):3311-7.
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2009: Jimenez-Dalmaroni Maximiliano J; Xiao Nengming; Corper Adam L; Verdino Petra; Ainge Gary D; Larsen Dave S; Painter Gavin F; Rudd Pauline M; Dwek Raymond A; Hoebe Kasper; Beutler Bruce; Wilson Ian A
Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
PloS one 2009;4(10):e7411.
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2008: Shore D A; Issafras H; Landais E; Teyton L; Wilson I A
The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I.
Journal of molecular biology 2008;384(5):1190-202.
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2008: Zajonc Dirk M; Striegl Harald; Dascher Christopher C; Wilson Ian A
The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(46):17925-30.
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2008: Xu Xiaojin; Zhu Xueyong; Dwek Raymond A; Stevens James; Wilson Ian A
Structural characterization of the 1918 influenza virus H1N1 neuraminidase.
Journal of virology 2008;82(21):10493-501.
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2008: Johnson Steven M; Connelly Stephen; Wilson Ian A; Kelly Jeffery W
Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
Journal of medicinal chemistry 2008;51(20):6348-58.
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2008: Han Byung Woo; Herrin Brantley R; Cooper Max D; Wilson Ian A
Antigen recognition by variable lymphocyte receptors.
Science (New York, N.Y.) 2008;321(5897):1834-7.
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2008: Stevens James; Blixt Ola; Chen Li-Mei; Donis Ruben O; Paulson James C; Wilson Ian A
Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity.
Journal of molecular biology 2008;381(5):1382-94.
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2008: Verdino Petra; Aldag Caroline; Hilvert Donald; Wilson Ian A
Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11725-30.
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2008: Zhu Xueyong; Xu Xiaojin; Wilson Ian A
Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects.
Acta crystallographica. Section D, Biological crystallography 2008;D64(Pt 8):843-50.
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2008: Dhillon Amandeep K; Stanfield Robyn L; Gorny Miroslaw K; Williams Constance; Zolla-Pazner Susan; Wilson Ian A
Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set.
Acta crystallographica. Section D, Biological crystallography 2008;D64(Pt 7):792-802.
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2008: Astronomo Rena D; Lee Hing-Ken; Scanlan Christopher N; Pantophlet Ralph; Huang Cheng-Yuan; Wilson Ian A; Blixt Ola; Dwek Raymond A; Wong Chi-Huey; Burton Dennis R
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
Journal of virology 2008;82(13):6359-68.
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2008: Relloso Miguel; Cheng Tan-Yun; Im Jin S; Parisini Emilio; Roura-Mir Carme; DeBono Charles; Zajonc Dirk M; Murga Leonel F; Ondrechen Mary Jo; Wilson Ian A; Porcelli Steven A; Moody D Branch
pH-dependent interdomain tethers of CD1b regulate its antigen capture.
Immunity 2008;28(6):774-86.
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2008: Debler Erik W; Müller Roger; Hilvert Donald; Wilson Ian A
Conformational isomerism can limit antibody catalysis.
The Journal of biological chemistry 2008;283(24):16554-60.
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2008: Menendez Alfredo; Calarese Daniel A; Stanfield Robyn L; Chow Keith C; Scanlan Chris N; Kunert Renate; Katinger Herman; Burton Dennis R; Wilson Ian A; Scott Jamie K
A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1380-92.
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2008: Zajonc Dirk M; Savage Paul B; Bendelac Albert; Wilson Ian A; Teyton Luc
Crystal structures of mouse CD1d-iGb3 complex and its cognate Valpha14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids.
Journal of molecular biology 2008;377(4):1104-16.
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2008: Debler Erik W; Kaufmann Gunnar F; Meijler Michael M; Heine Andreas; Mee Jenny M; Pljevaljcic Goran; Di Bilio Angel J; Schultz Peter G; Millar David P; Janda Kim D; Wilson Ian A; Gray Harry B; Lerner Richard A
Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science (New York, N.Y.) 2008;319(5867):1232-5.
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2008: Mathews Irimpan I; McMullan Daniel; Miller Mitchell D; Canaves Jaume M; Elsliger Marc-André; Floyd Ross; Grzechnik Slawomir K; Jaroszewski Lukasz; Klock Heath E; Koesema Eric; Kovarik John S; Kreusch Andreas; Kuhn Peter; McPhillips Timothy M; Morse Andrew T; Quijano Kevin; Rife Christopher L; Schwarzenbacher Robert; Spraggon Glen; Stevens Raymond C; van den Bedem Henry; Weekes Dana; Wolf Guenter; Hodgson Keith O; Wooley John; Deacon Ashley M; Godzik Adam; Lesley Scott A; Wilson Ian A
Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution.
Proteins 2008;70(2):603-8.
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2008: Johnson Steven M; Connelly Stephen; Wilson Ian A; Kelly Jeffery W
Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
Journal of medicinal chemistry 2008;51(2):260-70.
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2008: Bell Christian H; Pantophlet Ralph; Schiefner André; Cavacini Lisa A; Stanfield Robyn L; Burton Dennis R; Wilson Ian A
Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
Journal of molecular biology 2008;375(4):969-78.
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2007: Stoll Raphael; Lee Brian M; Debler Erik W; Laity John H; Wilson Ian A; Dyson H Jane; Wright Peter E
Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA.
Journal of molecular biology 2007;372(5):1227-45.
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2007: Burton Dennis R; Wilson Ian A
Immunology. Square-dancing antibodies.
Science (New York, N.Y.) 2007;317(5844):1507-8.
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2007: Huang Sha; Romanchuk Gail; Pattridge Katherine; Lesley Scott A; Wilson Ian A; Matthews Rowena G; Ludwig Martha
Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.
Protein science : a publication of the Protein Society 2007;16(8):1588-95.
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2007: Saphire Erica Ollmann; Montero Marinieve; Menendez Alfredo; van Houten Nienke E; Irving Melita B; Pantophlet Ralph; Zwick Michael B; Parren Paul W H I; Burton Dennis R; Scott Jamie K; Wilson Ian A
Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.
Journal of molecular biology 2007;369(3):696-709.
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2007: Debler Erik W; Kaufmann Gunnar F; Kirchdoerfer Robert N; Mee Jenny M; Janda Kim D; Wilson Ian A
Crystal structures of a quorum-quenching antibody.
Journal of molecular biology 2007;368(5):1392-402.
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2007: Xu Lan; Chong Youhoon; Hwang Inkyu; D'Onofrio Anthony; Amore Kristen; Beardsley G Peter; Li Chenglong; Olson Arthur J; Boger Dale L; Wilson Ian A
Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.
The Journal of biological chemistry 2007;282(17):13033-46.
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2007: Nelson Josh D; Brunel Florence M; Jensen Richard; Crooks Emma T; Cardoso Rosa M F; Wang Meng; Hessell Ann; Wilson Ian A; Binley James M; Dawson Philip E; Burton Dennis R; Zwick Michael B
An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10.
Journal of virology 2007;81(8):4033-43.
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2007: Law Mansun; Cardoso Rosa M F; Wilson Ian A; Burton Dennis R
Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy.
Journal of virology 2007;81(8):4272-85.
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2007: Weekes Dana; Miller Mitchell D; Krishna S Sri; McMullan Daniel; McPhillips Timothy M; Acosta Claire; Canaves Jaume M; Elsliger Marc-André; Floyd Ross; Grzechnik Slawomir K; Jaroszewski Lukasz; Klock Heath E; Koesema Eric; Kovarik John S; Kreusch Andreas; Morse Andrew T; Quijano Kevin; Spraggon Glen; van den Bedem Henry; Wolf Guenter; Hodgson Keith O; Wooley John; Deacon Ashley M; Godzik Adam; Lesley Scott A; Wilson Ian A
Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution.
Proteins 2007;67(1):247-52.
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2007: Stanfield Robyn L; Dooley Helen; Verdino Petra; Flajnik Martin F; Wilson Ian A
Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit binding.
Journal of molecular biology 2007;367(2):358-72.
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2007: Cardoso Rosa M F; Brunel Florence M; Ferguson Sharon; Zwick Michael; Burton Dennis R; Dawson Philip E; Wilson Ian A
Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
Journal of molecular biology 2007;365(5):1533-44.
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2007: Müller Roger; Debler Erik W; Steinmann Michael; Seebeck Florian P; Wilson Ian A; Hilvert Donald
Bifunctional catalysis of proton transfer at an antibody active site.
Journal of the American Chemical Society 2007;129(3):460-1.
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2007: Zajonc D M; Wilson I A
Architecture of CD1 proteins.
Current topics in microbiology and immunology 2007;314():27-50.
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2006: Cooper Ziva D; Narasimhan Diwahar; Sunahara Roger K; Mierzejewski Pawel; Jutkiewicz Emily M; Larsen Nicholas A; Wilson Ian A; Landry Donald W; Woods James H
Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase.
Molecular pharmacology 2006;70(6):1885-91.
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2006: Tian Feng; Debler Erik W; Millar David P; Deniz Ashok A; Wilson Ian A; Schultz Peter G
The effects of antibodies on stilbene excited-state energetics.
Angewandte Chemie (International ed. in English) 2006;45(46):7763-5.
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2006: Stevens James; Blixt Ola; Paulson James C; Wilson Ian A
Glycan microarray technologies: tools to survey host specificity of influenza viruses.
Nature reviews. Microbiology 2006;4(11):857-64.
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2006: Zajonc Dirk M; Ainge Gary D; Painter Gavin F; Severn Wayne B; Wilson Ian A
Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4577-83.
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2006: Schwarzenbacher Robert; McMullan Daniel; Krishna S Sri; Xu Qingping; Miller Mitchell D; Canaves Jaume M; Elsliger Marc-André; Floyd Ross; Grzechnik Slawomir K; Jaroszewski Lukasz; Klock Heath E; Koesema Eric; Kovarik John S; Kreusch Andreas; Kuhn Peter; McPhillips Timothy M; Morse Andrew T; Quijano Kevin; Spraggon Glen; Stevens Raymond C; van den Bedem Henry; Wolf Guenter; Hodgson Keith O; Wooley John; Deacon Ashley M; Godzik Adam; Lesley Scott A; Wilson Ian A
Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold.
Proteins 2006;65(1):243-8.
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2006: Kinjo Yuki; Tupin Emmanuel; Wu Douglass; Fujio Masakazu; Garcia-Navarro Raquel; Benhnia Mohammed Rafii-El-Idrissi; Zajonc Dirk M; Ben-Menachem Gil; Ainge Gary D; Painter Gavin F; Khurana Archana; Hoebe Kasper; Behar Samuel M; Beutler Bruce; Wilson Ian A; Tsuji Moriya; Sellati Timothy J; Wong Chi-Huey; Kronenberg Mitchell
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.
Nature immunology 2006;7(9):978-86.
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2006: Jiang Zhengfan; Georgel Philippe; Li Chenglong; Choe Jungwoo; Crozat Karine; Rutschmann Sophie; Du Xin; Bigby Tim; Mudd Suzanne; Sovath Sosathya; Wilson Ian A; Olson Arthur; Beutler Bruce
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(29):10961-6.
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2006: Cheng Tan-Yun; Relloso Miguel; Van Rhijn Ildiko; Young David C; Besra Gurdyal S; Briken Volker; Zajonc Dirk M; Wilson Ian A; Porcelli Steven; Moody D Branch
Role of lipid trimming and CD1 groove size in cellular antigen presentation.
The EMBO journal 2006;25(13):2989-99.
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2006: Stanfield Robyn L; Gorny Miroslaw K; Zolla-Pazner Susan; Wilson Ian A
Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
Journal of virology 2006;80(12):6093-105.
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2006: DeMartino Jessica K; Hwang Inkyu; Xu Lan; Wilson Ian A; Boger Dale L
Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase.
Journal of medicinal chemistry 2006;49(10):2998-3002.
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2006: Johnson Margaret A; Peti Wolfgang; Herrmann Torsten; Wilson Ian A; Wüthrich Kurt
Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence.
Protein science : a publication of the Protein Society 2006;15(5):1030-41.
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2006: Stevens James; Blixt Ola; Tumpey Terrence M; Taubenberger Jeffery K; Paulson James C; Wilson Ian A
Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus.
Science (New York, N.Y.) 2006;312(5772):404-10.
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2006: Shore D A; Teyton L; Dwek R A; Rudd P M; Wilson I A
Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.
Journal of molecular biology 2006;358(2):347-54.
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2006: Stanfield Robyn L; Zemla Adam; Wilson Ian A; Rupp Bernhard
Antibody elbow angles are influenced by their light chain class.
Journal of molecular biology 2006;357(5):1566-74.
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2006: Wu Douglass; Zajonc Dirk M; Fujio Masakazu; Sullivan Barbara A; Kinjo Yuki; Kronenberg Mitchell; Wilson Ian A; Wong Chi-Huey
Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(11):3972-7.
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2006: Zhu Xueyong; Wentworth Paul; Kyle Robert A; Lerner Richard A; Wilson Ian A
Cofactor-containing antibodies: crystal structure of the original yellow antibody.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3581-5.
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2006: Stauber Deborah J; Debler Erik W; Horton Patricia A; Smith Kendall A; Wilson Ian A
Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2788-93.
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2006: Zhu Xueyong; Dickerson Tobin J; Rogers Claude J; Kaufmann Gunnar F; Mee Jenny M; McKenzie Kathleen M; Janda Kim D; Wilson Ian A
Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure (London, England : 1993) 2006;14(2):205-16.
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2006: Brunel Florence M; Zwick Michael B; Cardoso Rosa M F; Nelson Josh D; Wilson Ian A; Burton Dennis R; Dawson Philip E
Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody.
Journal of virology 2006;80(4):1680-7.
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2006: Stevens James; Blixt Ola; Glaser Laurel; Taubenberger Jeffery K; Palese Peter; Paulson James C; Wilson Ian A
Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities.
Journal of molecular biology 2006;355(5):1143-55.
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2005: Zajonc Dirk M; Maricic Igor; Wu Douglass; Halder Ramesh; Roy Keshab; Wong Chi-Huey; Kumar Vipin; Wilson Ian A
Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity.
The Journal of experimental medicine 2005;202(11):1517-26.
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2005: Peti Wolfgang; Page Rebecca; Moy Kin; O'Neil-Johnson Mark; Wilson Ian A; Stevens Raymond C; Wüthrich Kurt
Towards miniaturization of a structural genomics pipeline using micro-expression and microcoil NMR.
Journal of structural and functional genomics 2005;6(4):259-67.
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2005: Almeida Marcius S; Herrmann Torsten; Peti Wolfgang; Wilson Ian A; Wüthrich Kurt
NMR structure of the conserved hypothetical protein TM0487 from Thermotoga maritima: implications for 216 homologous DUF59 proteins.
Protein science : a publication of the Protein Society 2005;14(11):2880-6.
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2005: Burton Dennis R; Stanfield Robyn L; Wilson Ian A
Antibody vs. HIV in a clash of evolutionary titans.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):14943-8.
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2005: Luz John G; Yu Minmin; Su Ying; Wu Zining; Zhou Zhou; Sun Ren; Wilson Ian A
Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
Journal of molecular biology 2005;352(5):1019-28.
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2005: Calarese Daniel A; Lee Hing-Ken; Huang Cheng-Yuan; Best Michael D; Astronomo Rena D; Stanfield Robyn L; Katinger Hermann; Burton Dennis R; Wong Chi-Huey; Wilson Ian A
Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13372-7.
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2005: Glaser Laurel; Stevens James; Zamarin Dmitriy; Wilson Ian A; García-Sastre Adolfo; Tumpey Terrence M; Basler Christopher F; Taubenberger Jeffery K; Palese Peter
A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity.
Journal of virology 2005;79(17):11533-6.
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2005: Zajonc Dirk M; Cantu Carlos; Mattner Jochen; Zhou Dapeng; Savage Paul B; Bendelac Albert; Wilson Ian A; Teyton Luc
Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor.
Nature immunology 2005;6(8):810-8.
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2005: Giabbai Barbara; Sidobre Stèphane; Crispin M D Max; Sanchez-Ruìz Yovan; Bachi Angela; Kronenberg Mitchell; Wilson Ian A; Degano Massimo
Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):977-84.
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2005: Choe Jungwoo; Kelker Matthew S; Wilson Ian A
Crystal structure of human toll-like receptor 3 (TLR3) ectodomain.
Science (New York, N.Y.) 2005;309(5734):581-5.
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2005: Van Rhijn Ildiko; Zajonc Dirk M; Wilson Ian A; Moody D Branch
T-cell activation by lipopeptide antigens.
Current opinion in immunology 2005;17(3):222-9.
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2005: Moody D Branch; Zajonc Dirk M; Wilson Ian A
Anatomy of CD1-lipid antigen complexes.
Nature reviews. Immunology 2005;5(5):387-99.
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2005: Cheng Heng; Hwang Inkyu; Chong Youhoon; Tavassoli Ali; Webb Michael E; Zhang Yan; Wilson Ian A; Benkovic Stephen J; Boger Dale L
Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway.
Bioorganic & medicinal chemistry 2005;13(10):3593-9.
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2005: Chong Youhoon; Hwang Inkyu; Tavassoli Ali; Zhang Yan; Wilson Ian A; Benkovic Stephen J; Boger Dale L
Synthesis and biological evaluation of alpha- and gamma-carboxamide derivatives of 10-CF3CO-DDACTHF.
Bioorganic & medicinal chemistry 2005;13(10):3587-92.
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2005: Cheng Heng; Chong Youhoon; Hwang Inkyu; Tavassoli Ali; Zhang Yan; Wilson Ian A; Benkovic Stephen J; Boger Dale L
Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.
Bioorganic & medicinal chemistry 2005;13(10):3577-85.
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2005: Zhang Yan; Wang Lei; Schultz Peter G; Wilson Ian A
Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine.
Protein science : a publication of the Protein Society 2005;14(5):1340-9.
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2005: Wiseman R Luke; Johnson Steven M; Kelker Matthew S; Foss Ted; Wilson Ian A; Kelly Jeffery W
Kinetic stabilization of an oligomeric protein by a single ligand binding event.
Journal of the American Chemical Society 2005;127(15):5540-51.
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2005: Debler Erik W; Ito Shuichiro; Seebeck Florian P; Heine Andreas; Hilvert Donald; Wilson Ian A
Structural origins of efficient proton abstraction from carbon by a catalytic antibody.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):4984-9.
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2005: Foss Ted R; Kelker Matthew S; Wiseman R Luke; Wilson Ian A; Kelly Jeffery W
Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis.
Journal of molecular biology 2005;347(4):841-54.
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2005: Zajonc Dirk M; Crispin M D Max; Bowden Thomas A; Young David C; Cheng Tan-Yun; Hu Jingdan; Costello Catherine E; Rudd Pauline M; Dwek Raymond A; Miller Marvin J; Brenner Michael B; Moody D Branch; Wilson Ian A
Molecular mechanism of lipopeptide presentation by CD1a.
Immunity 2005;22(2):209-19.
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2005: Cardoso Rosa M F; Zwick Michael B; Stanfield Robyn L; Kunert Renate; Binley James M; Katinger Hermann; Burton Dennis R; Wilson Ian A
Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41.
Immunity 2005;22(2):163-73.
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2005: Page Rebecca; Peti Wolfgang; Wilson Ian A; Stevens Raymond C; Wüthrich Kurt
NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):1901-5.
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2005: Hava David L; Brigl Manfred; van den Elzen Peter; Zajonc Dirk M; Wilson Ian A; Brenner Michael B
CD1 assembly and the formation of CD1-antigen complexes.
Current opinion in immunology 2005;17(1):88-94.
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2005: Stanfield Robyn L; Wilson Ian A
Structural studies of human HIV-1 V3 antibodies.
Human antibodies 2005;14(3-4):73-80.
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2005: Shore David A; Wilson Ian A; Dwek Raymond A; Rudd Pauline M
Glycosylation and the function of the T cell co-receptor CD8.
Advances in experimental medicine and biology 2005;564():71-84.
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2005: Lesley Scott A; Wilson Ian A
Protein production and crystallization at the joint center for structural genomics.
Journal of structural and functional genomics 2005;6(2-3):71-9.
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2004: Li Chenglong; Xu Lan; Wolan Dennis W; Wilson Ian A; Olson Arthur J
Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.
Journal of medicinal chemistry 2004;47(27):6681-90.
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2004: Blixt Ola; Head Steve; Mondala Tony; Scanlan Christopher; Huflejt Margaret E; Alvarez Richard; Bryan Marian C; Fazio Fabio; Calarese Daniel; Stevens James; Razi Nahid; Stevens David J; Skehel John J; van Die Irma; Burton Dennis R; Wilson Ian A; Cummings Richard; Bovin Nicolai; Wong Chi-Huey; Paulson James C
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17033-8.
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2004: Kelker Matthew S; Debler Erik W; Wilson Ian A
Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A.
Journal of molecular biology 2004;344(5):1175-81.
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2004: Spraggon Glen; Pantazatos Dennis; Klock Heath E; Wilson Ian A; Woods Virgil L; Lesley Scott A
On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171.
Protein science : a publication of the Protein Society 2004;13(12):3187-99.
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2004: Canaves Jaume M; Page Rebecca; Wilson Ian A; Stevens Raymond C
Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics.
Journal of molecular biology 2004;344(4):977-91.
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2004: Zhu Xueyong; Tanaka Fujie; Hu Yunfeng; Heine Andreas; Fuller Roberta; Zhong Guofu; Olson Arthur J; Lerner Richard A; Barbas Carlos F; Wilson Ian A
The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis.
Journal of molecular biology 2004;343(5):1269-80.
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2004: Xu Lan; Li Chenglong; Olson Arthur J; Wilson Ian A
Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening.
The Journal of biological chemistry 2004;279(48):50555-65.
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2004: Pantophlet R; Wilson I A; Burton D R
Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12.
Protein engineering, design & selection : PEDS 2004;17(10):749-58.
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2004: Wang Xiaodong; Matteson Jeanne; An Yu; Moyer Bryan; Yoo Jin-San; Bannykh Sergei; Wilson Ian A; Riordan John R; Balch William E
COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code.
The Journal of cell biology 2004;167(1):65-74.
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2004: Heine Andreas; Luz John G; Wong Chi-Huey; Wilson Ian A
Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution.
Journal of molecular biology 2004;343(4):1019-34.
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2004: Kelker Matthew S; Foss Theodore R; Peti Wolfgang; Teyton Luc; Kelly Jeffrey W; Wüthrich Kurt; Wilson Ian A
Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A.
Journal of molecular biology 2004;342(4):1237-48.
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2004: Stanfield Robyn L; Dooley Helen; Flajnik Martin F; Wilson Ian A
Crystal structure of a shark single-domain antibody V region in complex with lysozyme.
Science (New York, N.Y.) 2004;305(5691):1770-3.
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2004: Bryan Marian C; Fazio Fabio; Lee Hing-Ken; Huang Cheng-Yuan; Chang Aileen; Best Michael D; Calarese Daniel A; Blixt Ola; Paulson James C; Burton Dennis; Wilson Ian A; Wong Chi-Huey
Covalent display of oligosaccharide arrays in microtiter plates.
Journal of the American Chemical Society 2004;126(28):8640-1.
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2004: Reiser Jean-Baptiste; Teyton Luc; Wilson Ian A
Crystal structure of the Drosophila peptidoglycan recognition protein (PGRP)-SA at 1.56 A resolution.
Journal of molecular biology 2004;340(4):909-17.
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2004: Larsen N A; de Prada P; Deng S-X; Mittal A; Braskett M; Zhu X; Wilson I A; Landry D W
Crystallographic and biochemical analysis of cocaine-degrading antibody 15A10.
Biochemistry 2004;43(25):8067-76.
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2004: Crispin M D Max; Ritchie Gayle E; Critchley Alison J; Morgan B Paul; Wilson Ian A; Dwek Raymond A; Sim Robert B; Rudd Pauline M
Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure.
FEBS letters 2004;566(1-3):270-4.
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2004: Rudolph Markus G; Wingren Christer; Crowley Michael P; Chien Yueh Hsiu; Wilson Ian A
Combined pseudo-merohedral twinning, non-crystallographic symmetry and pseudo-translation in a monoclinic crystal form of the gammadelta T-cell ligand T10.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 4):656-64.
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2004: Cheong Cheom-Gil; Wolan Dennis W; Greasley Samantha E; Horton Patricia A; Beardsley G Peter; Wilson Ian A
Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.
The Journal of biological chemistry 2004;279(17):18034-45.
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2004: Zwick Michael B; Komori H Kiyomi; Stanfield Robyn L; Church Sarah; Wang Meng; Parren Paul W H I; Kunert Renate; Katinger Hermann; Wilson Ian A; Burton Dennis R
The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5.
Journal of virology 2004;78(6):3155-61.
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2004: Burton Dennis R; Desrosiers Ronald C; Doms Robert W; Koff Wayne C; Kwong Peter D; Moore John P; Nabel Gary J; Sodroski Joseph; Wilson Ian A; Wyatt Richard T
HIV vaccine design and the neutralizing antibody problem.
Nature immunology 2004;5(3):233-6.
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2004: Rudolph Markus G; Shen Lucy Q; Lamontagne Stephen A; Luz John G; Delaney Joseph R; Ge Qing; Cho Bryan K; Palliser Deborah; McKinley Carol A; Chen Jianzhu; Wilson Ian A; Eisen Herman N
A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2994-3002.
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2004: Stevens James; Corper Adam L; Basler Christopher F; Taubenberger Jeffery K; Palese Peter; Wilson Ian A
Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus.
Science (New York, N.Y.) 2004;303(5665):1866-70.
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2004: Zhu Xueyong; Wentworth Paul; Wentworth Anita D; Eschenmoser Albert; Lerner Richard A; Wilson Ian A
Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2247-52.
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2004: Lee Hing-Ken; Scanlan Christopher N; Huang Cheng-Yuan; Chang Aileen Y; Calarese Daniel A; Dwek Raymond A; Rudd Pauline M; Burton Dennis R; Wilson Ian A; Wong Chi-Huey
Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
Angewandte Chemie (International ed. in English) 2004;43(8):1000-3.
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2004: Stanfield Robyn L; Gorny Miroslaw K; Williams Constance; Zolla-Pazner Susan; Wilson Ian A
Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D.
Structure (London, England : 1993) 2004;12(2):193-204.
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2004: Wolan Dennis W; Cheong Cheom-Gil; Greasley Samantha E; Wilson Ian A
Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.
Biochemistry 2004;43(5):1171-83.
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2004: Moody D Branch; Young David C; Cheng Tan-Yun; Rosat Jean-Pierre; Roura-Mir Carme; O'Connor Peter B; Zajonc Dirk M; Walz Andrew; Miller Marvin J; Levery Steven B; Wilson Ian A; Costello Catherine E; Brenner Michael B
T cell activation by lipopeptide antigens.
Science (New York, N.Y.) 2004;303(5657):527-31.
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2004: Pantazatos Dennis; Kim Jack S; Klock Heath E; Stevens Raymond C; Wilson Ian A; Lesley Scott A; Woods Virgil L
Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(3):751-6.
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2003: Stanfield Robyn L; Ghiara Jayant B; Ollmann Saphire Erica; Profy Albert T; Wilson Ian A
Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop.
Virology 2003;315(1):159-73.
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2003: Desharnais Joel; Hwang Inkyu; Zhang Yan; Tavassoli Ali; Baboval Justin; Benkovic Stephen J; Wilson Ian A; Boger Dale L
Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.
Bioorganic & medicinal chemistry 2003;11(20):4511-21.
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2003: Marsilje Thomas H; Hedrick Michael P; Desharnais Joel; Capps Kevin; Tavassoli Ali; Zhang Yan; Wilson Ian A; Benkovic Stephen J; Boger Dale L
10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.
Bioorganic & medicinal chemistry 2003;11(20):4503-9.
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2003: Marsilje Thomas H; Hedrick Michael P; Desharnais Joel; Tavassoli Ali; Zhang Yan; Wilson Ian A; Benkovic Stephen J; Boger Dale L
Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.
Bioorganic & medicinal chemistry 2003;11(20):4487-501.
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2003: Wolan Dennis W; Greasley Samantha E; Wall Mark J; Benkovic Stephen J; Wilson Ian A
Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.
Biochemistry 2003;42(37):10904-14.
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2003: Rader Christoph; Turner James M; Heine Andreas; Shabat Doron; Sinha Subhash C; Wilson Ian A; Lerner Richard A; Barbas Carlos F
A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy.
Journal of molecular biology 2003;332(4):889-99.
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2003: Zajonc Dirk M; Elsliger Marc A; Teyton Luc; Wilson Ian A
Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A.
Nature immunology 2003;4(8):808-15.
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2003: Calarese Daniel A; Scanlan Christopher N; Zwick Michael B; Deechongkit Songpon; Mimura Yusuke; Kunert Renate; Zhu Ping; Wormald Mark R; Stanfield Robyn L; Roux Kenneth H; Kelly Jeffery W; Rudd Pauline M; Dwek Raymond A; Katinger Hermann; Burton Dennis R; Wilson Ian A
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science (New York, N.Y.) 2003;300(5628):2065-71.
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2003: Redwan El-Rashdy M; Larsen Nicholas A; Zhou Bin; Wirsching Peter; Janda Kim D; Wilson Ian A
Expression and characterization of a humanized cocaine-binding antibody.
Biotechnology and bioengineering 2003;82(5):612-8.
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2003: Zhang Yan; Desharnais Joel; Marsilje Thomas H; Li Chenglong; Hedrick Michael P; Gooljarsingh Lata T; Tavassoli Ali; Benkovic Stephen J; Olson Arthur J; Boger Dale L; Wilson Ian A
Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid.
Biochemistry 2003;42(20):6043-56.
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2003: Zhu Xueyong; Heine Andreas; Monnat Frédéric; Houk K N; Janda Kim D; Wilson Ian A
Structural basis for antibody catalysis of a cationic cyclization reaction.
Journal of molecular biology 2003;329(1):69-83.
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2003: Pantophlet Ralph; Wilson Ian A; Burton Dennis R
Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design.
Journal of virology 2003;77(10):5889-901.
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2003: Zwick Michael B; Parren Paul W H I; Saphire Erica O; Church Sarah; Wang Meng; Scott Jamie K; Dawson Philip E; Wilson Ian A; Burton Dennis R
Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120.
Journal of virology 2003;77(10):5863-76.
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2003: Royle Louise; Roos Anja; Harvey David J; Wormald Mark R; van Gijlswijk-Janssen Daniëlle; Redwan El-Rashdy M; Wilson Ian A; Daha Mohamed R; Dwek Raymond A; Rudd Pauline M
Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems.
The Journal of biological chemistry 2003;278(22):20140-53.
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2003: Luz John Gately; Hassig Christian A; Pickle Catherine; Godzik Adam; Meyer Barbara J; Wilson Ian A
XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators.
Genes & development 2003;17(8):977-90.
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2003: An Yu; Shao Ying; Alory Christelle; Matteson Jeanne; Sakisaka Toshiaki; Chen Wei; Gibbs Richard A; Wilson Ian A; Balch William E
Geranylgeranyl switching regulates GDI-Rab GTPase recycling.
Structure (London, England : 1993) 2003;11(3):347-57.
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2003: Zhu Yuerong; Rudensky Alexander Y; Corper Adam L; Teyton Luc; Wilson Ian A
Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif.
Journal of molecular biology 2003;326(4):1157-74.
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2003: Wentworth Paul; Wentworth Anita D; Zhu Xueyong; Wilson Ian A; Janda Kim D; Eschenmoser Albert; Lerner Richard A
Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1490-3.
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2003: Rudolph Markus G; Kelker Matthew S; Schneider Thomas R; Yeates Todd O; Oseroff Vanessa; Heidary David K; Jennings Patricia A; Wilson Ian A
Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 2):290-8.
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2003: Pantophlet Ralph; Ollmann Saphire Erica; Poignard Pascal; Parren Paul W H I; Wilson Ian A; Burton Dennis R
Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.
Journal of virology 2003;77(1):642-58.
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2003: DeSantis Grace; Liu Junjie; Clark David P; Heine Andreas; Wilson Ian A; Wong Chi-Huey
Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase.
Bioorganic & medicinal chemistry 2003;11(1):43-52.
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2003: Zhu Xueyong; Larsen Nicholas A; Basran Amrik; Bruce Neil C; Wilson Ian A
Observation of an arsenic adduct in an acetyl esterase crystal structure.
The Journal of biological chemistry 2003;278(3):2008-14.
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2003: Scanlan Christopher N; Pantophlet Ralph; Wormald Mark R; Saphire Erica Ollmann; Calarese Daniel; Stanfield Robyn; Wilson Ian A; Katinger Hermann; Dwek Raymond A; Burton Dennis R; Rudd Pauline M
The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.
Advances in experimental medicine and biology 2003;535():205-18.
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2003: Saphire Erica Ollmann; Stanfield Robyn L; Crispin M D Max; Morris Garrett; Zwick Michael B; Pantophlet Ralph A; Parren Paul W H I; Rudd Pauline M; Dwek Raymond A; Burton Dennis R; Wilson Ian A
Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
Advances in experimental medicine and biology 2003;535():55-66.
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2002: Wolan Dennis W; Greasley Samantha E; Beardsley G Peter; Wilson Ian A
Structural insights into the avian AICAR transformylase mechanism.
Biochemistry 2002;41(52):15505-13.
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2002: Rudolph Markus G; Stevens James; Speir Jeffrey A; Trowsdale John; Butcher Geoffrey W; Joly Etienne; Wilson Ian A
Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.
Journal of molecular biology 2002;324(5):975-90.
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2002: Larsen Nicholas A; Heine Andreas; de Prada Paloma; Redwan El-Rashdy; Yeates Todd O; Landry Donald W; Wilson Ian A
Structure determination of a cocaine hydrolytic antibody from a pseudomerohedrally twinned crystal.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):2055-9.
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2002: Zhang Yan; Desharnais Joel; Greasley Samantha E; Beardsley G Peter; Boger Dale L; Wilson Ian A
Crystal structures of human GAR Tfase at low and high pH and with substrate beta-GAR.
Biochemistry 2002;41(48):14206-15.
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2002: Turner James M; Larsen Nicholas A; Basran Amrik; Barbas Carlos F; Bruce Neil C; Wilson Ian A; Lerner Richard A
Biochemical characterization and structural analysis of a highly proficient cocaine esterase.
Biochemistry 2002;41(41):12297-307.
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2002: Lesley Scott A; Kuhn Peter; Godzik Adam; Deacon Ashley M; Mathews Irimpan; Kreusch Andreas; Spraggon Glen; Klock Heath E; McMullan Daniel; Shin Tanya; Vincent Juli; Robb Alyssa; Brinen Linda S; Miller Mitchell D; McPhillips Timothy M; Miller Mark A; Scheibe Daniel; Canaves Jaume M; Guda Chittibabu; Jaroszewski Lukasz; Selby Thomas L; Elsliger Marc-Andre; Wooley John; Taylor Susan S; Hodgson Keith O; Wilson Ian A; Schultz Peter G; Stevens Raymond C
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11664-9.
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2002: Marsilje Thomas H; Labroli Marc A; Hedrick Michael P; Jin Qing; Desharnais Joel; Baker Stephen J; Gooljarsingh Lata T; Ramcharan Joseph; Tavassoli Ali; Zhang Yan; Wilson Ian A; Beardsley G Peter; Benkovic Stephen J; Boger Dale L
10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.
Bioorganic & medicinal chemistry 2002;10(8):2739-49.
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2002: Scanlan Christopher N; Pantophlet Ralph; Wormald Mark R; Ollmann Saphire Erica; Stanfield Robyn; Wilson Ian A; Katinger Hermann; Dwek Raymond A; Rudd Pauline M; Burton Dennis R
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.
Journal of virology 2002;76(14):7306-21.
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2002: Apostolopoulos Vasso; Yu Minmin; Corper Adam L; Li Wenjun; McKenzie Ian F C; Teyton Luc; Wilson Ian A; Plebanski Magdalena
Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.
Journal of molecular biology 2002;318(5):1307-16.
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2002: Apostolopoulos Vasso; Yu Minmin; Corper Adam L; Teyton Luc; Pietersz Geoffrey A; McKenzie Ian F C; Wilson Ian A; Plebanski Magdalena
Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.
Journal of molecular biology 2002;318(5):1293-305.
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2002: Saphire Erica Ollmann; Stanfield Robyn L; Crispin M D Max; Parren Paul W H I; Rudd Pauline M; Dwek Raymond A; Burton Dennis R; Wilson Ian A
Contrasting IgG structures reveal extreme asymmetry and flexibility.
Journal of molecular biology 2002;319(1):9-18.
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2002: Luz John G; Huang Mingdong; Garcia K Christopher; Rudolph Markus G; Apostolopoulos Vasso; Teyton Luc; Wilson Ian A
Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions.
The Journal of experimental medicine 2002;195(9):1175-86.
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2002: Grant Ethan P; Beckman Evan M; Behar Samuel M; Degano Massimo; Frederique Daphney; Besra Gurdyal S; Wilson Ian A; Porcelli Steven A; Furlong Stephen T; Brenner Michael B
Fine specificity of TCR complementarity-determining region residues and lipid antigen hydrophilic moieties in the recognition of a CD1-lipid complex.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3933-40.
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2002: Huang Mingdong; Weissman Jacques T; Wang Chenqian; Balch William E; Wilson Ian A
Protein engineering for crystallization of the GTPase Sar1 that regulates ER vesicle budding.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 4):700-3.
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2002: Wilson Ian A
Don C. Wiley.
Nature structural biology 2002;9(3):164-6.
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2002: Rudolph Markus G; Wilson Ian A
The specificity of TCR/pMHC interaction.
Current opinion in immunology 2002;14(1):52-65.
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2002: Hotta Kinya; Wilson Ian A; Hilvert Donald
Probing ligand recognition in the decarboxylase antibody 21D8: implications for the catalytic mechanism.
Biochemistry 2002;41(3):772-9.
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2002: Larsen Nicholas A; Turner James M; Stevens James; Rosser Susan J; Basran Amrik; Lerner Richard A; Bruce Neil C; Wilson Ian A
Crystal structure of a bacterial cocaine esterase.
Nature structural biology 2002;9(1):17-21.
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2002: Rudolph Markus G; Luz John G; Wilson Ian A
Structural and thermodynamic correlates of T cell signaling.
Annual review of biophysics and biomolecular structure 2002;31():121-49.
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2001: Huang M; Weissman J T; Beraud-Dufour S; Luan P; Wang C; Chen W; Aridor M; Wilson I A; Balch W E
Crystal structure of Sar1-GDP at 1.7 A resolution and the role of the NH2 terminus in ER export.
The Journal of cell biology 2001;155(6):937-48.
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2001: Larsen N A; Heine A; Crane L; Cravatt B F; Lerner R A; Wilson I A
Structural basis for a disfavored elimination reaction in catalytic antibody 1D4.
Journal of molecular biology 2001;314(1):93-102.
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2001: Rudolph M G; Huang M; Teyton L; Wilson I A
Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.
Journal of molecular biology 2001;314(1):1-8.
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2001: Greasley S E; Marsilje T H; Cai H; Baker S; Benkovic S J; Boger D L; Wilson I A
Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase.
Biochemistry 2001;40(45):13538-47.
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2001: Heine A; DeSantis G; Luz J G; Mitchell M; Wong C H; Wilson I A
Observation of covalent intermediates in an enzyme mechanism at atomic resolution.
Science (New York, N.Y.) 2001;294(5541):369-74.
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2001: Stevens R C; Yokoyama S; Wilson I A
Global efforts in structural genomics.
Science (New York, N.Y.) 2001;294(5540):89-92.
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2001: Wentworth P; Jones L H; Wentworth A D; Zhu X; Larsen N A; Wilson I A; Xu X; Goddard W A; Janda K D; Eschenmoser A; Lerner R A
Antibody catalysis of the oxidation of water.
Science (New York, N.Y.) 2001;293(5536):1806-11.
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2001: Saphire E O; Parren P W; Pantophlet R; Zwick M B; Morris G M; Rudd P M; Dwek R A; Stanfield R L; Burton D R; Wilson I A
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.
Science (New York, N.Y.) 2001;293(5532):1155-9.
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2001: Larsen N A; Zhou B; Heine A; Wirsching P; Janda K D; Wilson I A
Crystal structure of a cocaine-binding antibody.
Journal of molecular biology 2001;311(1):9-15.
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2001: Wilson I A; Stanfield R L
Unraveling the mysteries of gammadelta T cell recognition.
Nature immunology 2001;2(7):579-81.
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2001: Greasley S E; Horton P; Ramcharan J; Beardsley G P; Benkovic S J; Wilson I A
Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
Nature structural biology 2001;8(5):402-6.
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2001: Rudolph M G; Speir J A; Brunmark A; Mattsson N; Jackson M R; Peterson P A; Teyton L; Wilson I A
The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity 2001;14(3):231-42.
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2001: Rudd P M; Elliott T; Cresswell P; Wilson I A; Dwek R A
Glycosylation and the immune system.
Science (New York, N.Y.) 2001;291(5512):2370-6.
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2001: Wolan D W; Teyton L; Rudolph M G; Villmow B; Bauer S; Busch D H; Wilson I A
Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A.
Nature immunology 2001;2(3):248-54.
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2001: Beutler E; West C; Speir J A; Wilson I A; Worley M
The hHFE gene of browsing and grazing rhinoceroses: a possible site of adaptation to a low-iron diet.
Blood cells, molecules & diseases 2001;27(1):342-50.
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2001: Speir J A; Stevens J; Joly E; Butcher G W; Wilson I A
Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa.
Immunity 2001;14(1):81-92.
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2001: Saphire E O; Parren P W; Barbas C F; Burton D R; Wilson I A
Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 1):168-71.
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2000: Hotta K; Lange H; Tantillo D J; Houk K N; Hilvert D; Wilson I A
Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.
Journal of molecular biology 2000;302(5):1213-25.
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2000: Stratmann T; Apostolopoulos V; Mallet-Designe V; Corper A L; Scott C A; Wilson I A; Kang A S; Teyton L
The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3214-25.
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2000: Reyes V M; Greasley S E; Stura E A; Beardsley G P; Wilson I A
Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 8):1051-4.
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2000: Corper A L; Stratmann T; Apostolopoulos V; Scott C A; Garcia K C; Kang A S; Wilson I A; Teyton L
A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes.
Science (New York, N.Y.) 2000;288(5465):505-11.
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2000: Karlstrom A; Zhong G; Rader C; Larsen N A; Heine A; Fuller R; List B; Tanaka F; Wilson I A; Barbas C F; Lerner R A
Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):3878-83.
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2000: Luan P; Heine A; Zeng K; Moyer B; Greasely S E; Kuhn P; Balch W E; Wilson I A
A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling.
Traffic (Copenhagen, Denmark) 2000;1(3):270-81.
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2000: Degano M; Garcia K C; Apostolopoulos V; Rudolph M G; Teyton L; Wilson I A
A functional hot spot for antigen recognition in a superagonist TCR/MHC complex.
Immunity 2000;12(3):251-61.
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2000: Wingren C; Crowley M P; Degano M; Chien Y; Wilson I A
Crystal structure of a gammadelta T cell receptor ligand T22: a truncated MHC-like fold.
Science (New York, N.Y.) 2000;287(5451):310-4.
-
1999: Moody D B; Besra G S; Wilson I A; Porcelli S A
The molecular basis of CD1-mediated presentation of lipid antigens.
Immunological reviews 1999;172():285-96.
-
1999: Wilson I A
Perspectives: protein structure. Class-conscious TCR?
Science (New York, N.Y.) 1999;286(5446):1867-8.
-
1999: Wilson I A; Jolliffe L K
The structure, organization, activation and plasticity of the erythropoietin receptor.
Current opinion in structural biology 1999;9(6):696-704.
-
1999: Greasley S E; Yamashita M M; Cai H; Benkovic S J; Boger D L; Wilson I A
New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.
Biochemistry 1999;38(51):16783-93.
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1999: Xu J; Deng Q; Chen J; Houk K N; Bartek J; Hilvert D; Wilson I A
Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.
Science (New York, N.Y.) 1999;286(5448):2345-8.
-
1999: Rudd P M; Wormald M R; Stanfield R L; Huang M; Mattsson N; Speir J A; DiGennaro J A; Fetrow J S; Dwek R A; Wilson I A
Roles for glycosylation of cell surface receptors involved in cellular immune recognition.
Journal of molecular biology 1999;293(2):351-66.
-
1999: Gruber K; Zhou B; Houk K N; Lerner R A; Shevlin C G; Wilson I A
Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry 1999;38(22):7062-74.
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1999: Middleton S A; Barbone F P; Johnson D L; Thurmond R L; You Y; McMahon F J; Jin R; Livnah O; Tullai J; Farrell F X; Goldsmith M A; Wilson I A; Jolliffe L K
Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide.
The Journal of biological chemistry 1999;274(20):14163-9.
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1999: Livnah O; Stura E A; Middleton S A; Johnson D L; Jolliffe L K; Wilson I A
Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation.
Science (New York, N.Y.) 1999;283(5404):987-90.
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1999: Speir J A; Abdel-Motal U M; Jondal M; Wilson I A
Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL.
Immunity 1999;10(1):51-61.
-
1999: Grant E P; Degano M; Rosat J P; Stenger S; Modlin R L; Wilson I A; Porcelli S A; Brenner M B
Molecular recognition of lipid antigens by T cell receptors.
The Journal of experimental medicine 1999;189(1):195-205.
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1999: Garcia K C; Degano M; Speir J A; Wilson I A
Emerging principles for T cell receptor recognition of antigen in cellular immunity.
Reviews in immunogenetics 1999;1(1):75-90.
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1999: Garcia K C; Teyton L; Wilson I A
Structural basis of T cell recognition.
Annual review of immunology 1999;17():369-97.
-
1998: Livnah O; Johnson D L; Stura E A; Farrell F X; Barbone F P; You Y; Liu K D; Goldsmith M A; He W; Krause C D; Pestka S; Jolliffe L K; Wilson I A
An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
Nature structural biology 1998;5(11):993-1004.
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1998: Su Y; Yamashita M M; Greasley S E; Mullen C A; Shim J H; Jennings P A; Benkovic S J; Wilson I A
A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A.
Journal of molecular biology 1998;281(3):485-99.
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1998: Speir J A; Garcia K C; Brunmark A; Degano M; Peterson P A; Teyton L; Wilson I A
Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes.
Immunity 1998;8(5):553-62.
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1998: Manning T C; Schlueter C J; Brodnicki T C; Parke E A; Speir J A; Garcia K C; Teyton L; Wilson I A; Kranz D M
Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition.
Immunity 1998;8(4):413-25.
-
1998: Scott C A; Peterson P A; Teyton L; Wilson I A
Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues.
Immunity 1998;8(3):319-29.
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1998: Johnson D L; Farrell F X; Barbone F P; McMahon F J; Tullai J; Hoey K; Livnah O; Wrighton N C; Middleton S A; Loughney D A; Stura E A; Dower W J; Mulcahy L S; Wilson I A; Jolliffe L K
Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1.
Biochemistry 1998;37(11):3699-710.
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1998: Heine A; Stura E A; Yli-Kauhaluoma J T; Gao C; Deng Q; Beno B R; Houk K N; Janda K D; Wilson I A
An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution.
Science (New York, N.Y.) 1998;279(5358):1934-40.
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1998: Wilson I A; Bjorkman P J
Unusual MHC-like molecules: CD1, Fc receptor, the hemochromatosis gene product, and viral homologs.
Current opinion in immunology 1998;10(1):67-73.
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1998: Scott C A; Garcia K C; Stura E A; Peterson P A; Wilson I A; Teyton L
Engineering protein for X-ray crystallography: the murine Major Histocompatibility Complex class II molecule I-Ad.
Protein science : a publication of the Protein Society 1998;7(2):413-8.
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1998: Huang M; Syed R; Stura E A; Stone M J; Stefanko R S; Ruf W; Edgington T S; Wilson I A
The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex.
Journal of molecular biology 1998;275(5):873-94.
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1998: Garcia K C; Degano M; Pease L R; Huang M; Peterson P A; Teyton L; Wilson I A
Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.
Science (New York, N.Y.) 1998;279(5354):1166-72.
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1997: Wilson I A; Garcia K C
T-cell receptor structure and TCR complexes.
Current opinion in structural biology 1997;7(6):839-48.
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1997: Barbas C F; Heine A; Zhong G; Hoffmann T; Gramatikova S; Björnestedt R; List B; Anderson J; Stura E A; Wilson I A; Lerner R A
Immune versus natural selection: antibody aldolases with enzymic rates but broader scope.
Science (New York, N.Y.) 1997;278(5346):2085-92.
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1997: Garcia K C; Tallquist M D; Pease L R; Brunmark A; Scott C A; Degano M; Stura E A; Peterson P A; Wilson I A; Teyton L
Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13838-43.
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1997: Zeng Z; Castaño A R; Segelke B W; Stura E A; Peterson P A; Wilson I A
Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove.
Science (New York, N.Y.) 1997;277(5324):339-45.
-
1997: He M; Gani M; Livnah O; Stura E A; Beale D; Coley J; Wilson I A; Taussig M J
Sequence, specificity and crystallization of an oestrone-3-glucuronide antibody (3910).
Immunology 1997;90(4):632-9.
-
1997: Ghiara J B; Ferguson D C; Satterthwait A C; Dyson H J; Wilson I A
Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.
Journal of molecular biology 1997;266(1):31-9.
-
1996: Wu S K; Zeng K; Wilson I A; Balch W E
Structural insights into the function of the Rab GDI superfamily.
Trends in biochemical sciences 1996;21(12):472-6.
-
1996: Garcia K C; Scott C A; Brunmark A; Carbone F R; Peterson P A; Wilson I A; Teyton L
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes.
Nature 1996;384(6609):577-81.
-
1996: Garcia K C; Degano M; Stanfield R L; Brunmark A; Jackson M R; Peterson P A; Teyton L; Wilson I A
An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
Science (New York, N.Y.) 1996;274(5285):209-19.
-
1996: Livnah O; Stura E A; Johnson D L; Middleton S A; Mulcahy L S; Wrighton N C; Dower W J; Jolliffe L K; Wilson I A
Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.
Science (New York, N.Y.) 1996;273(5274):464-71.
-
1996: Scott C A; Garcia K C; Carbone F R; Wilson I A; Teyton L
Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules.
The Journal of experimental medicine 1996;183(5):2087-95.
-
1996: Wilson I A
Another twist to MHC-peptide recognition.
Science (New York, N.Y.) 1996;272(5264):973-4.
-
1996: Schalk I; Zeng K; Wu S K; Stura E A; Matteson J; Huang M; Tandon A; Wilson I A; Balch W E
Structure and mutational analysis of Rab GDP-dissociation inhibitor.
Nature 1996;381(6577):42-8.
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1995: Lewicki H; Tishon A; Borrow P; Evans C F; Gairin J E; Hahn K M; Jewell D A; Wilson I A; Oldstone M B
CTL escape viral variants. I. Generation and molecular characterization.
Virology 1995;210(1):29-40.
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1995: Klein C; Chen P; Arevalo J H; Stura E A; Marolewski A; Warren M S; Benkovic S J; Wilson I A
Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.
Journal of molecular biology 1995;249(1):153-75.
-
1995: Stura E A; Ghosh S; Garcia-Junceda E; Chen L; Wong C H; Wilson I A
Crystallization and preliminary crystallographic data for class I deoxyribose-5-phosphate aldolase from Escherichia coli: an application of reverse screening.
Proteins 1995;22(1):67-72.
-
1995: Fremont D H; Stura E A; Matsumura M; Peterson P A; Wilson I A
Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2479-83.
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1995: Stanfield R L; Wilson I A
Protein-peptide interactions.
Current opinion in structural biology 1995;5(1):103-13.
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1994: Schalk I J; Stura E A; Matteson J; Wilson I A; Balch W E
Crystallization and preliminary crystallographic data for Rab guanine nucleotide dissociation inhibitor (RabGDI) from bovine brain.
Journal of molecular biology 1994;244(4):469-73.
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1994: Wilson I A; Stanfield R L
Antibody-antigen interactions: new structures and new conformational changes.
Current opinion in structural biology 1994;4(6):857-67.
-
1994: Arevalo J H; Hassig C A; Stura E A; Sims M J; Taussig M J; Wilson I A
Structural analysis of antibody specificity. Detailed comparison of five Fab'-steroid complexes.
Journal of molecular biology 1994;241(5):663-90.
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1994: Churchill M E; Stura E A; Pinilla C; Appel J R; Houghten R A; Kono D H; Balderas R S; Fieser G G; Schulze-Gahmen U; Wilson I A
Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.
Journal of molecular biology 1994;241(4):534-56.
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1994: Stura E A; Satterthwait A C; Calvo J C; Kaslow D C; Wilson I A
Reverse screening.
Acta crystallographica. Section D, Biological crystallography 1994;50(Pt 4):448-55.
-
1994: Stanfield R L; Wilson I A
Antigen-induced conformational changes in antibodies: a problem for structural prediction and design.
Trends in biotechnology 1994;12(7):275-9.
-
1994: Wilson I A
Covalently linked ligand stabilizes expression of heterodimeric receptor.
Structure (London, England : 1993) 1994;2(6):561-2.
-
1994: Wilson I A; Stanfield R L; Jewell D A; Ghiara J B; Fremont D H; Stura E A
Immune recognition of viral antigens.
Infectious agents and disease 1994;3(2-3):155-62.
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1994: Ghiara J B; Stura E A; Stanfield R L; Profy A T; Wilson I A
Crystal structure of the principal neutralization site of HIV-1.
Science (New York, N.Y.) 1994;264(5155):82-5.
-
1994: Haynes M R; Stura E A; Hilvert D; Wilson I A
Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart.
Science (New York, N.Y.) 1994;263(5147):646-52.
-
1994: Haynes M R; Stura E A; Hilvert D; Wilson I A
Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition state analog.
Proteins 1994;18(2):198-200.
-
1994: Gani M; Coley J; Piron J; Humphreys A S; Arevalo J; Wilson I A; Taussig M J
Monoclonal antibodies against progesterone: effect of steroid-carrier coupling position on antibody specificity.
The Journal of steroid biochemistry and molecular biology 1994;48(2-3):277-82.
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1994: Wilson I A; Ghiara J B; Stanfield R L
Structure of anti-peptide antibody complexes.
Research in immunology 1994;145(1):73-8.
-
1993: Schulze-Gahmen U; Rini J M; Wilson I A
Detailed analysis of the free and bound conformations of an antibody. X-ray structures of Fab 17/9 and three different Fab-peptide complexes.
Journal of molecular biology 1993;234(4):1098-118.
-
1993: Arevalo J H; Taussig M J; Wilson I A
Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature 1993;365(6449):859-63.
-
1993: Stanfield R L; Takimoto-Kamimura M; Rini J M; Profy A T; Wilson I A
Major antigen-induced domain rearrangements in an antibody.
Structure (London, England : 1993) 1993;1(2):83-93.
-
1993: Rini J M; Stanfield R L; Stura E A; Salinas P A; Profy A T; Wilson I A
Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6325-9.
-
1993: Arevalo J H; Stura E A; Taussig M J; Wilson I A
Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex.
Journal of molecular biology 1993;231(1):103-18.
-
1993: Wilson I A; Fremont D H
Structural analysis of MHC class I molecules with bound peptide antigens.
Seminars in immunology 1993;5(2):75-80.
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1992: Stura E A; Matsumura M; Fremont D H; Saito Y; Peterson P A; Wilson I A
Crystallization of murine major histocompatibility complex class I H-2Kb with single peptides.
Journal of molecular biology 1992;228(3):975-82.
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1992: Stura E A; Stanfield R L; Fieser G G; Silver S; Roguska M; Hincapie L M; Simmerman H K; Profy A T; Wilson I A
Crystallization, sequence, and preliminary crystallographic data for an antipeptide Fab 50.1 and peptide complexes with the principal neutralizing determinant of HIV-1 gp120.
Proteins 1992;14(4):499-508.
-
1992: Chen P; Schulze-Gahmen U; Stura E A; Inglese J; Johnson D L; Marolewski A; Benkovic S J; Wilson I A
Crystal structure of glycinamide ribonucleotide transformylase from Escherichia coli at 3.0 A resolution. A target enzyme for chemotherapy.
Journal of molecular biology 1992;227(1):283-92.
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1992: Matsumura M; Fremont D H; Peterson P A; Wilson I A
Emerging principles for the recognition of peptide antigens by MHC class I molecules.
Science (New York, N.Y.) 1992;257(5072):927-34.
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1992: Fremont D H; Matsumura M; Stura E A; Peterson P A; Wilson I A
Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.
Science (New York, N.Y.) 1992;257(5072):919-27.
-
1992: Rini J M; Schulze-Gahmen U; Wilson I A
Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science (New York, N.Y.) 1992;255(5047):959-65.
-
1992: Stura E A; Chen P; Wilmot C M; Arevalo J H; Wilson I A
Crystallization studies of glycosylated and unglycosylated human recombinant interleukin-2.
Proteins 1992;12(1):24-30.
-
1991: Wilson I A; Stanfield R L; Rini J M; Arevalo J H; Schulze-Gahmen U; Fremont D H; Stura E A
Structural aspects of antibodies and antibody-antigen complexes.
Ciba Foundation symposium 1991;159():13-28; discussion 28-39.
-
1991: Wilson I A; Rini J M; Fremont D H; Fieser G G; Stura E A
X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition.
Methods in enzymology 1991;203():153-76.
-
1990: Stanfield R L; Fieser T M; Lerner R A; Wilson I A
Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.
Science (New York, N.Y.) 1990;248(4956):712-9.
-
1990: Wilson I A; Cox N J
Structural basis of immune recognition of influenza virus hemagglutinin.
Annual review of immunology 1990;8():737-71.
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1989: Stura E A; Stanfield R L; Fieser T M; Balderas R S; Smith L R; Lerner R A; Wilson I A
Preliminary crystallographic data and primary sequence for anti-peptide Fab' B13I2 and its complex with the C-helix peptide from myohemerythrin.
The Journal of biological chemistry 1989;264(26):15721-5.
-
1989: Lambert G; Stura E A; Wilson I A
Crystallization and preliminary X-ray diffraction studies of a complex between interleukin-2 and a soluble form of the p55 component of the high affinity interleukin-2 receptor.
The Journal of biological chemistry 1989;264(21):12730-6.
-
1989: Stura E A; Johnson D L; Inglese J; Smith J M; Benkovic S J; Wilson I A
Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase.
The Journal of biological chemistry 1989;264(16):9703-6.
-
1988: Schulze-Gahmen U; Rini J M; Arevalo J; Stura E A; Kenten J H; Wilson I A
Preliminary crystallographic data, primary sequence, and binding data for an anti-peptide Fab and its complex with a synthetic peptide from influenza virus hemagglutinin.
The Journal of biological chemistry 1988;263(32):17100-5.
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1987: Stura E A; Arevalo J H; Feinstein A; Heap R B; Taussig M J; Wilson I A
Analysis of an anti-progesterone antibody: variable crystal morphology of the Fab' and steroid-Fab' complexes.
Immunology 1987;62(4):511-21.
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